Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment
Abstract
OBJECTIVE: To identify biological evidence for Alzheimer disease (AD) in individuals with subjective memory impairment (SMI) and unimpaired cognitive performance and to investigate the longitudinal cognitive course in these subjects. METHOD: [¹⁸F]fluoro-2-deoxyglucose PET (FDG-PET) and structural MRI were acquired in 31 subjects with SMI and 56 controls. Cognitive follow-up testing was performed (average follow-up time: 35 months). Differences in baseline brain imaging data and in memory decline were assessed between both groups. Associations of memory decline with brain imaging data were tested. RESULTS: The SMI group showed hypometabolism in the right precuneus and hypermetabolism in the right medial temporal lobe. Gray matter volume was reduced in the right hippocampus in the SMI group. At follow-up, subjects with SMI showed a poorer performance than controls on measures of episodic memory. Longitudinal memory decline in the SMI group was associated with reduced glucose metabolism in the right precuneus at baseline. CONCLUSION: The cross-sectional difference in 2 independent neuroimaging modalities indicates early AD pathology in SMI. The poorer memory performance at follow-up and the association of reduced longitudinal memory performance with hypometabolism in the precuneus at baseline support the concept of SMI as the earliest manifestation of AD.
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Longitudinal reduction in cognitive performance is associated with brain hypometabolism in the precuneus at baseline, but not with gray matter atrophy.
“In longitudinal studies using FDG-PET and MRI modalities, the longitudinal reduction in cognitive performance was associated with brain hypometabolism in the precuneus at baseline, but not with gray matter atrophy [59].”
From Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease (2020) · cites this paper as [59]
Regional reductions in brain glucose utilization occur with aging and to a greater extent in MCI and AD.
“Regional reductions in brain glucose utilization occur with aging and to a greater extent in MCI and AD [185-193].”
From The Alzheimer’s disease mitochondrial cascade hypothesis: progress and perspectives (2014) · cites this paper as [193]
Cites
An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032 · see citing works
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., Klunk, W. E., Koroshetz, W. J., Manly, J. J., Mayeux, R., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.005 · Cited by 18,657 · see citing works
Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., Gamst, A., Holtzman, D. M., Jagust, W. J., Petersen, R. C., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.008 · Cited by 10,152 · see citing works
A fast diffeomorphic image registration algorithm
Ashburner, J. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.07.007 · Cited by 8,122 · see citing works
Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, C. R., Kaye, J., Montine, T. J., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.003 · Cited by 7,155 · see citing works
Maldjian, J., Laurienti, P., Kraft, R., & Burdette, J. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00169-1 · Cited by 5,453 · see citing works
Winblad, B., Palmer, K., Kivipelto, M., Jelic, V., Fratiglioni, L., Wahlund, L. ‐., Nordberg, A., Bäckman, L., Albert, M., Almkvist, O., et al. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01380.x · Cited by 4,946 · see citing works
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
Jack, C. R., Knopman, D. S., Jagust, W. J., Shaw, L. M., Aisen, P. S., Weiner, M. W., Petersen, R. C., & Trojanowski, J. Q. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70299-6 · Cited by 4,806 · see citing works
A Voxel-Based Morphometric Study of Ageing in 465 Normal Adult Human Brains
Good, C. D., Johnsrude, I. S., Ashburner, J., Henson, R. N. A., Friston, K. J., & Frackowiak, R. S. J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0786 · Cited by 4,561 · see citing works
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS–ADRDA criteria
Dubois, B., Feldman, H. H., Jacova, C., DeKosky, S. T., Barberger-Gateau, P., Cummings, J., Delacourte, A., Galasko, D., Gauthier, S., Jicha, G., et al. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70178-3 · Cited by 4,411 · see citing works
Moms, J. C., Heyman, A., Mohs, R. C., Hughes, J. P., van Belle, G., Fillenbaum, G., Mellits, E. D., & Clark, C. (1989) · Neurology · doi:10.1212/wnl.39.9.1159 · Cited by 4,130 · see citing works
Gauthier, S. G., Reisberg, ., Zaudig, M., Petersen, R. C., Ritchie, K. A., Broich, K., Belleville, S., Brodaty, H., Bennett, D. A., Chertkow, H. M., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68542-5 · Cited by 3,920 · see citing works
Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.
Hixson, J., & Vernier, D. (1990) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)43176-1 · Cited by 2,933 · see citing works
Revising the definition of Alzheimer's disease: a new lexicon
Dubois, B., Feldman, H. H., Jacova, C., Cummings, J. L., DeKosky, S. T., Barberger-Gateau, P., Delacourte, A., Frisoni, G., Fox, N. C., Galasko, D., et al. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(10)70223-4 · Cited by 1,869 · see citing works
The Mini-Cog: a cognitive ?vital signs? measure for dementia screening in multi-lingual elderly
Soo Borson, B., Scanlan, J. M., Brush, M. B., VITALIANO, P. P., & Dokmak, A. (2000) · International Journal of Geriatric Psychiatry · doi:10.1002/1099-1166(200011)15:11 · Cited by 1,792 · see citing works
Patterns of Brain Activation in People at Risk for Alzheimer's Disease
Bookheimer, S. Y., Strojwas, M. H., Cohen, M. S., Saunders, A. M., Pericak-Vance, M. A., Mazziotta, J. C., & Small, G. W. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008173430701 · Cited by 1,328 · see citing works
CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment
Mattsson, N. (2009) · JAMA · doi:10.1001/jama.2009.1064 · Cited by 1,176 · see citing works
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
Rowe, C. C., Ellis, K. A., Rimajova, M., Bourgeat, P., Pike, K. E., Jones, G., Fripp, J., Tochon-Danguy, H., Morandeau, L., O'Keefe, G., et al. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2010.04.007 · Cited by 986 · see citing works
Prodromal Alzheimer's disease: successive emergence of the clinical symptoms
Amieva, H., Le Goff, M., Millet, X., Orgogozo, J. M., Pérès, K., Barberger‐Gateau, P., Jacqmin‐Gadda, H., & Dartigues, J. F. (2008) · Annals of Neurology · doi:10.1002/ana.21509 · Cited by 737 · see citing works
Jessen, F. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.30 · Cited by 681 · see citing works
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Reid, L. M., & MacLullich, A. M. J. (2006) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000096295 · Cited by 633 · see citing works
Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives
Hampel, H. J., Frank, R., Broich, K., Teipel, S. J., Katz, R. G., Hardy, J., Herholz, K., Bokde, A. L. W., Jessen, F., Hoessler, Y. C., et al. (2010) · Nature Reviews Drug Discovery · doi:10.1038/nrd3115 · Cited by 630 · see citing works
Self-citationVisser, P. J., Verhey, F., Knol, D. L., Scheltens, P., Wahlund, L.-O., Freund-Levi, Y., Tsolaki, M., Minthon, L., Wallin, Å. K., Hampel, H., et al. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70139-5 · Cited by 614 · see citing works
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Saykin, A. J., Wishart, H. A., Rabin, L. A., Santulli, R. B., Flashman, L. A., West, J. D., McHugh, T., & Mamourian, A. C. (2006) · Neurology · doi:10.1212/01.wnl.0000234032.77541.a2 · Cited by 584 · see citing works
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Psychotic-like experiences in the general population: characterizing a high-risk group for psychosis
Kelleher, I., & Cannon, M. D. (2010) · Psychological Medicine · doi:10.1017/s0033291710001005 · Cited by 567 · see citing works
A total score for the CERAD neuropsychological battery
Chandler, M. J., Lacritz, L. H., Hynan, L. S., Barnard, H. D., Allen, G., Deschner, M., Weiner, M. F., & Cullum, C. M. (2005) · Neurology · doi:10.1212/01.wnl.0000167607.63000.38 · Cited by 387 · see citing works
Volume reduction of the entorhinal cortex in subjective memory impairment
Jessen, F., Feyen, L., Freymann, K., Tepest, R., Maier, W., Heun, R., Schild, H. H., & Scheef, L. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.10.010 · Cited by 276 · see citing works
Self-citationMosconi, L., De Santi, S., Brys, M., Tsui, W. H., Pirraglia, E., Glodzik-Sobanska, L., Rich, K. E., Switalski, R., Mehta, P. D., Pratico, D., et al. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.05.030 · Cited by 238 · see citing works
The value of informant versus individual’s complaints of memory impairment in early dementia
Carr, D. B., Gray, S. G., Baty, J., & Morris, J. C. (2000) · Neurology · doi:10.1212/wnl.55.11.1724 · Cited by 191 · see citing works
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Striepens, N., Scheef, L., Wind, A., Popp, J., Spottke, A. E., Cooper‐Mahkorn, D., Suliman, H., Wagner, M., Schild, H. H., & Jessen, F. (2010) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000264630 · Cited by 182 · see citing works
Self-citationLarger temporal volume in elderly with high versus low beta-amyloid deposition
Chételat, G., Villemagne, V. L., Pike, K. E., Baron, J.-C., Bourgeat, P., Jones, G., Faux, N. G., Ellis, K. A., Salvado, O., Szoeke, C., et al. (2010) · Brain · doi:10.1093/brain/awq187 · Cited by 159 · see citing works
Patterns of subjective memory impairment in the elderly: association with memory performance
Jessen, F., Wiese, B., Cvetanovska, G., Fuchs, Â., Kaduszkiewicz, H., Kölsch, H., Luck, T., Mösch, E., Pentzek, M., Riedel-Heller, S. G., et al. (2007) · Psychological Medicine · doi:10.1017/s0033291707001122 · Cited by 157 · see citing works
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Endpoints for trials in Alzheimer's disease: a European task force consensus
Vellas, B. J., Andrieu, S., Sampaio, C., Coley, N., & Wilcock, G. K. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70087-5 · Cited by 146 · see citing works
Enhanced brain activity may precede the diagnosis of Alzheimer's disease by 30 years
Mondadori, C. R. A., Buchmann, A., Mustovic, H., Schmidt, C. F., Boesiger, P., Nitsch, R. M., Höck, C., Streffer, J. R., & Henke, K. (2006) · Brain · doi:10.1093/brain/awl266 · Cited by 118 · see citing works
Striepens, N., Scheef, L., Wind, A., Meiberth, D. U., Popp, J., Spottke, A. E., Kölsch, H., Wagner, M., & Jessen, F. (2011) · Psychological Medicine · doi:10.1017/s0033291711000067 · Cited by 63 · see citing works
Self-citationNorms for an abbreviated Raven's Coloured Progressive Matrices in an older sample
Smits, C. H. M., Smit, J. H., van den Heuvel, N., & Jonker, C. (1997) · Journal of Clinical Psychology · doi:10.1002/(sici)1097-4679(199711)53:7 · Cited by 42 · see citing works
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Jessen, F., Amariglio, R. E., van Boxtel, M., Breteler, M., Ceccaldi, M., Chételat, G., Dubois, B., Dufouil, C., Ellis, K. A., van der Flier, W. M., et al. (2014) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.01.001 · Cited by 3,014 · see citing works
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Swerdlow, R. H., Burns, J. M., & Khan, S. M. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.09.010 · Cited by 786 · see citing works
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Jahn, H. (2013) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2013.15.4/hjahn · Cited by 653 · see citing works
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Jessen, F., Wolfsgruber, S., Wiese, B., Bickel, H., Mösch, E., Kaduszkiewicz, H., Pentzek, M., Riedel‐Heller, S. G., Luck, T., Fuchs, A., et al. (2014) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2012.09.017 · Cited by 511 · see citing works
Self-citationNeuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease
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Self-citationPerrotin, A., La Joie, R., de La Sayette, V., Barré, L., Mézenge, F., Mutlu, J., Guilloteau, D., Egret, S., Eustache, F., & Chételat, G. (2017) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2016.08.011 · Cited by 179 · see citing works
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Shu, N., Wang, X., Bi, Q., Zhao, T., & Han, Y. (2018) · Radiology · doi:10.1148/radiol.2017162696 · Cited by 135 · see citing works
Snitz, B. E., Weissfeld, L. A., Cohen, A. D., Lopez, O. L., Nebes, R. D., Aizenstein, H. J., McDade, E., Price, J. C., Mathis, C. A., & Klunk, W. E. (2015) · The American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2015.01.008 · Cited by 140 · see citing works
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Schultz, S. A., Oh, J. M., Koscik, R. L., Dowling, N. M., Gallagher, C. L., Carlsson, C. M., Bendlin, B. B., LaRue, A., Hermann, B. P., Rowley, H. A., et al. (2015) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring · doi:10.1016/j.dadm.2014.11.010 · Cited by 117 · see citing works
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Fernández-Blázquez, M. A., Ávila-Villanueva, M., Maestú, F., & Medina, M. (2016) · Journal of Alzheimer's Disease · doi:10.3233/jad-150956 · Cited by 98 · see citing works
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Self-citationAmyloid PET and cognitive decline in cognitively normal individuals: the SCIENCe project
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Stenfors, C. U. D., Marklund, P., Magnusson Hanson, L. L., Theorell, T., & Nilsson, L.-G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083351 · Cited by 58 · see citing works
Lista, S., Molinuevo, J. L., Cavedo, E., Rami, L., Amouyel, P., Teipel, S. J., Garaci, F., Toschi, N., Habert, M.-O., Blennow, K., et al. (2015) · Journal of Alzheimer's Disease · doi:10.3233/jad-150202 · Cited by 53 · see citing works
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Fan, L., Lai, Y., Chen, T., Hsu, Y., Chen, P., Huang, K., Cheng, T., Tseng, W. I., Hua, M., Chen, Y., et al. (2018) · Human Brain Mapping · doi:10.1002/hbm.24022 · Cited by 40 · see citing works
Verfaillie, S. C. J., Slot, R. E., Tijms, B. M., Bouwman, F., Benedictus, M. R., Overbeek, J. M., Koene, T., Vrenken, H., Scheltens, P., Barkhof, F., et al. (2018) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2017.09.009 · Cited by 40 · see citing works
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Song, I.-U., Choi, E. K., Oh, J. K., Chung, Y.-A., & Chung, S.-W. (2016) · Acta Radiologica · doi:10.1177/0284185114566088 · Cited by 17 · see citing works
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- Authors
- Scheef, L., Spottke, A., Daerr, M., Joe, A., Striepens, N., Kölsch, H., Popp, J., Daamen, M., Gorris, D., Heneka, M. T., Boecker, H., Biersack, H. J., Maier, W., Schild, H. H., Wagner, M., & Jessen, F.
- Affiliations
- University of Bonn (DE)
- ORCID
- Venue
- Neurology
- Published
- 2012-09-25
- Volume
- 79
- Issue
- 13
- Pages
- 1332-1339
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2127591453
- Cited by
- 277
- References
- 38
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 18 · 2023: 10 · 2022: 20 · 2021: 33 · 2020: 31 · 2019: 28 · 2018: 22 · 2017: 21 · 2016: 18 · 2015: 22 · 2014: 20 · 2013: 19 · 2012: 3
- FWCI
- 14.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- IRIS (submittedVersion)
- Open Repository and Bibliography (University of Luxembourg) (submittedVersion)
- DZNE Pub (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
- Keywords
- subjective memory impairment, Alzheimer's disease, memory decline, glucose metabolism, episodic memory
- MeSH terms
- Aged, Brain, Female, Follow-Up Studies, Glucose, Humans, Magnetic Resonance Imaging, Male, Memory Disorders, Neuropsychological Tests, Fluorodeoxyglucose F18, Positron-Emission Tomography, Memory, Episodic
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