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Effects of Induced Metabolic Alkalosis on Prolonged Intermittent-Sprint Performance
Abstract
Purpose Previous studies have shown that induced metabolic alkalosis, via sodium bicarbonate (NaHCO3) ingestion, can improve short-term, repeated-sprint ability. The purpose of this study was to assess the effects of NaHCO3 ingestion on a prolonged, intermittent-sprint test (IST). Methods Seven female team-sport athletes (mean +/- SD: age = 19 +/- 1 yr, VO2peak = 45.3 +/- 3.1 mL x kg(-1) x min(-1)) volunteered for the study, which had received ethics clearance. The athletes ingested two doses of either 0.2 g x kg(-1) of NaHCO3 or 0.138 g x kg(-1) of NaCl (placebo), in a double-blind, random, counterbalanced order, 90 and 20 min before performing the IST on a cycle ergometer (two 36-min "halves" of repeated approximately 2-min blocks: all-out 4-s sprint, 100 s of active recovery at 35% VO2peak, and 20 s of rest). Capillary blood samples were drawn from the ear lobe before ingestion, and before, during, and after each half of the IST. VO2 was also recorded at regular intervals throughout the IST. Results Resting plasma bicarbonate concentration ([HCO3-]) averaged 22.6 +/- 0.9 mmol x L(-1), and at 90 min post-ingestion was 21.4 +/- 1.5 and 28.9 +/- 2.8 mmol x L-1 for the placebo and NaHCO3 conditions, respectively (P Conclusions The results of this study suggest that NaHCO3 ingestion can improve intermittent-sprint performance and may be a useful supplement for team-sport athletes.
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“Each experiment was separated by at least 7 days (1 week was considered a sufficient washout period to eliminate any ergogenic effect of sodium bicarbonate (Bishop and Claudius, 2005)).”
From Acute enteric-coated sodium bicarbonate has negligible effect on anaerobic performance but affects metabolomics and attenuates the gastrointestinal response (2022) · cites this paper as Bishop and Claudius, 2005
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McKay, A. K. A., Peeling, P., Binnie, M. J., Goods, P. S. R., Sim, M., Cross, R. L., & Siegler, J. C. (2020) · International Journal of Sports Physiology and Performance · doi:10.1123/ijspp.2019-0345 · Cited by 12
Lassen, T., Lindström, L., Lønbro, S., & Madsen, K. (2021) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2020-0352 · Cited by 10
Zhou, N., Fan, Y., Wang, X., Wang, J., & Wu, H. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.996381 · Cited by 8
“Each experiment was separated by at least 7 days (1 week was considered a sufficient washout period to eliminate any ergogenic effect of sodium bicarbonate (Bishop and Claudius, 2005)).”
MethodPouzash, R., Azarbayjani, M. A., Jebreeil, P. J., Azali, K., & Fatolahi, H. (2012) · Baltic Journal of Health and Physical Activity · doi:10.2478/v10131-012-0009-9 · Cited by 8
Cholewa, J. M., Grannis, D., Jaffe, D. A., Guimarães‐Ferreira, L., Matthews, T. D., & Paolone, V. J. (2015) · Journal of Trainology · doi:10.17338/trainology.4.1_19 · Cited by 7
Ruscello, B., Pantanella, L., Iemme, P., Filetti, C., Porta, M., D'Ottavio, S., Marcelli, L., Apollaro, G., Morganti, G., Grossi, A., et al. (2022) · The Journal of Sports Medicine and Physical Fitness · doi:10.23736/s0022-4707.22.13822-3 · Cited by 6
Heredia‐Jimenez, J., Ríos, I. J. C., Casas, J. Á. R., & Ríos, L. J. C. (2009) · Apunts Sports Medicine · doi:10.1016/s1886-6581(09)70127-6 · Cited by 6
Hyperventilation-Aided Recovery for Extra Repetitions on Bench Press and Leg Press
Sakamoto, A., Naıto, H., & Chow, C. M. (2020) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003506 · Cited by 6
Acute effect of sodium bicarbonate supplementation on the performance during CrossFit® training
Toledo, L. P., Vieira, J. G., & Dias, M. R. (2020) · Motriz Revista de Educação Física · doi:10.1590/s1980-6574202000040075 · Cited by 6
Metadata
- Authors
- BISHOP, D., & CLAUDIUS, B.
- Affiliations
- The University of Western Australia (AU)
- ORCID
- BISHOP, DAVID
- Venue
- Medicine & Science in Sports & Exercise
- Published
- 2005-05
- Volume
- 37
- Issue
- 5
- Pages
- 759-767
- ISSN
- 0195-9131 (ISSN-L)
- OpenAlex
- W2093437177
- Cited by
- 155
- References
- 26
- Citations by year
- 2026: 5 · 2025: 4 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 11 · 2020: 13 · 2019: 5 · 2018: 12 · 2017: 5 · 2016: 4 · 2015: 12 · 2014: 5 · 2013: 13 · 2012: 12
- FWCI
- 4.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Medicine & Science in Sports & Exercise (publishedVersion)
- PubMed (publishedVersion)
- Victoria University Research Repository (Victoria University) (submittedVersion)
- UWA Profiles and Research Repository (UWA) (submittedVersion)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Keywords
- metabolic alkalosis, sodium bicarbonate ingestion, repeated sprint ability, plasma bicarbonate, team sport athletes, endurance performance, active recovery
- MeSH terms
- Adult, Alkalosis, Bicarbonates, Double-Blind Method, Drug Administration Schedule, Female, Heart Rate, Humans, Hydrogen-Ion Concentration, Oxygen Consumption, Pulmonary Gas Exchange, Running, Ergometry, Sodium Bicarbonate, Lactic Acid
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