The DOI matches its Crossref record; 111 of the 131 references it cites were found in a registry or an index.
The Navigation Guide—Evidence-Based Medicine Meets Environmental Health: Systematic Review of Human Evidence for PFOA Effects on Fetal Growth
Open accessAbstract
Background: The Navigation Guide methodology was developed to meet the need for a robust method of systematic and transparent research synthesis in environmental health science. We conducted a case study systematic review to support proof of concept of the method. Objective: We applied the Navigation Guide systematic review methodology to determine whether developmental exposure to perfluorooctanoic acid (PFOA) affects fetal growth in humans. Methods: We applied the first 3 steps of the Navigation Guide methodology to human epidemiological data: 1) specify the study question, 2) select the evidence, and 3) rate the quality and strength of the evidence. We developed a protocol, conducted a comprehensive search of the literature, and identified relevant studies using prespecified criteria. We evaluated each study for risk of bias and conducted meta-analyses on a subset of studies. We rated quality and strength of the entire body of human evidence. Results: We identified 18 human studies that met our inclusion criteria, and 9 of these were combined through meta-analysis. Through meta-analysis, we estimated that a 1-ng/mL increase in serum or plasma PFOA was associated with a –18.9 g (95% CI: –29.8, –7.9) difference in birth weight. We concluded that the risk of bias across studies was low, and we assigned a “moderate” quality rating to the overall body of human evidence. Conclusion: On the basis of this first application of the Navigation Guide systematic review methodology, we concluded that there is “sufficient” human evidence that developmental exposure to PFOA reduces fetal growth. Citation: Johnson PI, Sutton P, Atchley DS, Koustas E, Lam J, Sen S, Robinson KA, Axelrad DA, Woodruff TJ. 2014. The Navigation Guide—evidence-based medicine meets environmental health: systematic review of human evidence for PFOA effects on fetal growth. Environ Health Perspect 122:1028–1039; http://dx.doi.org/10.1289/ehp.1307893
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“such methods have only recently been developed and utilized in environmental health sciences [23–30].”
From A Systematic Review and Meta-Analysis of Multiple Airborne Pollutants and Autism Spectrum Disorder (2016) · cites this paper as [30]
In the citing paper
“This observation is consistent with our previous systematic reviews, [24, 27, 28, 30]”
From A Systematic Review and Meta-Analysis of Multiple Airborne Pollutants and Autism Spectrum Disorder (2016) · cites this paper as [30]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139
Meta-analysis in clinical trials
DerSimonian, R., & Laird, N. (1986) · Controlled Clinical Trials · doi:10.1016/0197-2456(86)90046-2 · Cited by 39,552 · cited 2×
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1031 across studies (DerSimonian and Laird 1986).”
BackgroundCochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048 · cited 5×
“Such methods already exist to evaluate clinical evidence (GRADE Working Group 2012; Higgins and Green 2011) and include steps such as developing an a priori protocol, a comprehensive search, and rating the quality of the evidence.”
BackgroundMethodInfluentialvon Elm, E., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., Vandenbroucke, J. P., & Initiative, F. T. S. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040296 · Cited by 23,020 · cited 2×
“Future reviews could be strengthened if more investigators followed standardized reporting criteria such as the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines (von Elm et al. 2008), enabling improved quality assessment.”
Conducting Meta-Analyses in R with the metafor Package
Viechtbauer, W. (2010) · Journal of Statistical Software · doi:10.18637/jss.v036.i03 · Cited by 20,464
Elm, E. V., Altman, D. G., Egger, M., Pocock, S. J., Gøtzsche, P. C., & Vandenbroucke, J. P. (2007) · BMJ · doi:10.1136/bmj.39335.541782.ad · Cited by 10,766 · cited 2×
“Future reviews could be strengthened if more investigators followed standardized reporting criteria such as the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines (von Elm et al. 2008), enabling improved quality assessment.”
BackgroundMethodGRADE guidelines: 3. Rating the quality of evidence
Balshem, H., Helfand, M., Schünemann, H. J., Oxman, A. D., Kunz, R., Brozek, J., Vist, G. E., Falck-Ytter, Y., Meerpohl, J., & Norris, S. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.07.015 · Cited by 8,285 · cited 4×
“In assessing quality and strength according to factors and considera tions that had not been pre specified, we conducted further analysis and abided by GRADE’s principle to be conservative in changing the rating of the body of evidence up or down (Balshem et al. 2011).”
MethodInfluentialSterne, J. A. C., Sutton, A. J., Ioannidis, J. P. A., Terrin, N., Jones, D. R., Lau, J., Carpenter, J., Rucker, G., Harbord, R. M., Schmid, C. H., et al. (2011) · BMJ · doi:10.1136/bmj.d4002 · Cited by 7,709
GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)
Guyatt, G. H., Oxman, A. D., Vist, G., Kunz, R., Brozek, J., Alonso-Coello, P., Montori, V., Akl, E. A., Djulbegovic, B., & Falck-Ytter, Y. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.07.017 · Cited by 2,798 · cited 3×
“Evaluation factors Summary of criteria Downgrading factors Risk of bias Study limitations include a substantial risk of bias across the body of evidence.”
BackgroundMethodPerfluoroalkyl Acids: A Review of Monitoring and Toxicological Findings
Lau, C., Anitole, K., Hodes, C., Lai, D., Pfahles-Hutchens, A., & Seed, J. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm128 · Cited by 2,620 · cited 2×
“…the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 2007; Lindstrom et al. 2011; Olsen et al. 2009; Post et al. 2012; Steenland et al. 2010; White et al. 2011).”
BackgroundSources, fate and transport of perfluorocarboxylates
Prevedouros, K., Cousins, I. T., Buck, R. C., & Korzeniowski, S. H. (2006) · Environmental Science & Technology · doi:10.1021/es0512475 · Cited by 2,594 · cited 2×
“PFOA has been used for > 50 years in the manufacture of fluoro polymers used in industrial applications and consumer products to impart certain charac teristics, such as fire and stain resistance [Prevedouros et al. 2006; U.S. Environmental Protection Agency (EPA) 2012].”
BackgroundMethodOlsen, G. W., Burris, J. M., Ehresman, D. J., Froehlich, J. W., Seacat, A. M., Butenhoff, J. L., & Zobel, L. R. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10009 · Cited by 2,049
Polyfluorinated Compounds: Past, Present, and Future
Lindstrom, A. B., Strynar, M. J., & Libelo, E. L. (2011) · Environmental Science & Technology · doi:10.1021/es2011622 · Cited by 1,628 · cited 2×
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 20…”
BackgroundAzzalini, A., & Capitanio, A. (2003) · Journal of the Royal Statistical Society Series B (Statistical Methodology) · doi:10.1111/1467-9868.00391 · Cited by 1,572 · cited 2×
“We assumed that the data follow a skew tdistribution (Azzalini and Capitanio 2003), allowing us to fit a continuous distribution to the grouped data and producing a better fit to the data than assuming a normal distribution.”
MethodThe Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies.
Gláucia, F., Marcos, R. D. S., Tatiani, O. F., & Ana, R. (2013) · doi:10.1371/journal.pntd.0002195.t004 · Cited by 1,564
Sanderson, S., Tatt, I. D., & Higgins, J. P. (2007) · International Journal of Epidemiology · doi:10.1093/ije/dym018 · Cited by 1,531 · cited 2×
“Although there is existing guidance for assessing risk of bias of human obser vational studies (Viswanathan et al. 2012; Wells 2014), there is no universally accepted tool (Sanderson et al. 2007).”
BackgroundMethodCan Animal Models of Disease Reliably Inform Human Studies?
van der Worp, H. B., Howells, D. W., Sena, E. S., Porritt, M. J., Rewell, S., O'Collins, V., & Macleod, M. R. (2010) · PLoS Medicine · doi:10.1371/journal.pmed.1000245 · Cited by 1,354
GRADE guidelines: 9. Rating up the quality of evidence
Guyatt, G. H., Oxman, A. D., Sultan, S., Glasziou, P., Akl, E. A., Alonso-Coello, P., Atkins, D., Kunz, R., Brozek, J., Montori, V., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.06.004 · Cited by 1,336 · cited 2×
“…study charac teristics, exposure assessment, outcome measurements, and information used to assess risk of bias using a structured form in DistillerSR; we created this form by combining aspects of existing criteria and checklists (Guyatt et al. 2011b; Higgins and Deeks 2011; von Elm et al. 2008).”
MethodA call for transparent reporting to optimize the predictive value of preclinical research
Landis, S. C., Amara, S. G., Asadullah, K., Austin, C. P., Blumenstein, R., Bradley, E. W., Crystal, R. G., Darnell, R. B., Ferrante, R. J., Fillit, H., et al. (2012) · Nature · doi:10.1038/nature11556 · Cited by 1,196
Perfluorooctanesulfonate and related fluorochemicals in human blood from several countries
Kannan, K., Corsolini, S., Falandysz, J., Fillmann, G., Kumar, K. S., Loganathan, B. G., Mohd, M. A., Olivero, J., Wouwe, N. V., Yang, J. H., et al. (2004) · Environmental Science & Technology · doi:10.1021/es0493446 · Cited by 1,056
Environmental chemicals in pregnant women in the United States: NHANES 2003–2004
Woodruff, T. J., Zota, A. R., & Schwartz, J. M. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1002727 · Cited by 930 · cited 2×
“Rating the strength of the evidence across the human studies summarizes the human evidence; this summary will allow for the integration of human and non human streams of evidence, ultimately leading to a concise statement about a chemical’s toxicity (Woodruff et al. 2011a).”
BackgroundSelf-citationThe Developmental Toxicity of Perfluoroalkyl Acids and Their Derivatives
Lau, C., Butenhoff, J. L., & Rogers, J. M. (2004) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2003.11.031 · Cited by 867 · cited 2×
“…the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 2007; Lindstrom et al. 2011; Olsen et al. 2009; Post et al. 2012; Steenland et al. 2010; White et al. 2011).”
BackgroundTrends in Exposure to Polyfluoroalkyl Chemicals in the U.S. Population: 1999−2008
Kato, K., Wong, L.-Y., Jia, L. T., Kuklenyik, Z., & Calafat, A. M. (2011) · Environmental Science & Technology · doi:10.1021/es1043613 · Cited by 777 · cited 2×
“We selected PFOA for evaluation based on pervasive human exposure and the evidence of asso ciations with fetal growth (Agency for Toxic Substances and Disease Registry 2009; Apelberg et al. 2007; Fei et al. 2007, 2008; Kato et al. 2011; U.S. EPA 2012).”
MethodThe toxicology of perfluorooctanoate
Kennedy, G. L., Butenhoff, J. L., Olsen, G. W., O'Connor, J. C., Seacat, A. M., Perkins, R. G., Biegel, L. B., Murphy, S. R., & Farrar, D. G. (2004) · Critical Reviews in Toxicology · doi:10.1080/10408440490464705 · Cited by 742 · cited 2×
“association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004; Lau et al. 2007; Lindstrom et al. 2011; Olsen et al. 2009; Post et al. 2012; Steenland et al. 2010; White et al. 2011).”
BackgroundPooling of Animal Experimental Data Reveals Influence of Study Design and Publication Bias
Macleod, M. R., O’Collins, T., Howells, D. W., & Donnan, G. A. (2004) · Stroke · doi:10.1161/01.str.0000125719.25853.20 · Cited by 734
Epidemiologic Evidence on the Health Effects of Perfluorooctanoic Acid (PFOA)
Steenland, K., Fletcher, T., & Savitz, D. A. (2010) · Environmental Health Perspectives · doi:10.1289/ehp.0901827 · Cited by 660 · cited 2×
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 20…”
BackgroundPost, G. B., Cohn, P. D., & Cooper, K. R. (2012) · Environmental Research · doi:10.1016/j.envres.2012.03.007 · Cited by 639 · cited 2×
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 20…”
BackgroundPerfluorinated Chemicals and Fetal Growth: A Study within the Danish National Birth Cohort
Fei, C., McLaughlin, J. K., Tarone, R. E., & Olsen, J. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10506 · Cited by 636 · cited 14×
“2011); and between first and second trimester maternal plasma (Fei et al. 2007).”
BackgroundMethodInfluentialApelberg, B. J., Witter, F. R., Herbstman, J. B., Calafat, A. M., Halden, R. U., Needham, L. L., & Goldman, L. R. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10334 · Cited by 630 · cited 8×
“Study PFOA increase PFOA range (ng/mL) Covariates Apelberg et al. 2007 ln ng/mL 0.3–7.1 ga Apelberg et al. 2007 ln ng/mL 0.3–7.1 ga, ma, bmi, race, par, smk, sex, ht, wtg, dia, hyp Apelberg et al. 2007 25th to 75th percentile 1.2–2.1 ga Apelberg et al. 2007 25th to 75th percentile 1.2–2.1 ga, ma, bmi, race, par, smk,…”
BackgroundMethodInfluentialIndustry sponsorship and research outcome
Lundh, A., Sismondo, S., Lexchin, J., Busuioc, O. A., & Bero, L. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.mr000033.pub2 · Cited by 605 · cited 2×
“We also included the funding source and declared conflicts of interest as a potential source of bias based on empirical data from studies conducted on phar macological treatments that reported evidence of bias associated with funding source (Krauth et al. 2013; Lundh et al. 2012).”
MethodEffects of Perfluorooctanoic Acid Exposure during Pregnancy in the Mouse
Lau, C. S., Thibodeaux, J. R., Hanson, R. G., Narotsky, M. G., Rogers, J. M., Lindstrom, A. B., & Strynar, M. J. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj105 · Cited by 554
Chapter 5: Defining the review question and developing criteria for including studies
O'Connor, D. A., Green, S., & Higgins, J. (2008) · doi:10.1002/9780470712184.ch5 · Cited by 539
Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis.
van der Worp, H. B., Sena, E., Donnan, G., Howells, D., & Macleod, M. (2007) · Brain : a journal of neurology · doi:10.1093/brain/awm083 · Cited by 520
How to obtain the P value from a confidence interval
Altman, D., & Bland, J. (2011) · British medical journal · doi:10.1136/bmj.d2304 · Cited by 481 · cited 1×
“Because Hamm et al. (2010) provided only an unadjusted estimate and pvalue on a natural log (ln) transformed scale, we made a log transforma tion for this study to obtain the untransformed estimate, and the standard error was calculated from the pvalue (Altman and Bland 2011; Higgins et al. 2008).”
MethodCalafat, A., Kuklenyik, Z., Reidy, J., Caudill, S., Tully, J. S., & Needham, L. (2007) · Environmental Science and Technology · doi:10.1021/es062686m · Cited by 468
Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions
Viswanathan, M., Patnode, C. D., Berkman, N. D., Bass, E. B., Chang, S., Hartling, L., Murad, M. H., Treadwell, J. R., & Kane, R. L. (2017) · doi:10.23970/ahrqepcmethguide2 · Cited by 454
How to obtain the confidence interval from a P value
Altman, D., & Bland, J. (2011) · British medical journal · doi:10.1136/bmj.d2090 · Cited by 450 · cited 1×
“Because Hamm et al. (2010) provided only an unadjusted estimate and pvalue on a natural log (ln) transformed scale, we made a log transforma tion for this study to obtain the untransformed estimate, and the standard error was calculated from the pvalue (Altman and Bland 2011; Higgins et al. 2008).”
MethodMeta-analysis of skewed data: Combining results reported on log-transformed or raw scales
Higgins, J., White, I., & Anzures-Cabrera, J. (2008) · Statistics in Medicine · doi:10.1002/sim.3427 · Cited by 441 · cited 2×
“Evaluation factors Summary of criteria Downgrading factors Risk of bias Study limitations include a substantial risk of bias across the body of evidence.”
BackgroundMethodEnvironmental and Toxicity Effects of Perfluoroalkylated Substances
Hekster, F. M., Laane, R. W. P. M., & de Voogt, P. (2003) · Reviews of Environmental Contamination and Toxicology · doi:10.1007/0-387-21731-2_4 · Cited by 429 · cited 2×
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 20…”
BackgroundEmerging endocrine disrupters: perfluoroalkylated substances
Jensen, A. A., & Leffers, H. C. B. (2008) · International Journal of Andrology · doi:10.1111/j.1365-2605.2008.00870.x · Cited by 428 · cited 1×
“…have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 2007; Lindstrom et al. 2011; Olsen et al. 2009; Post et…”
Woodruff, T. J., & Sutton, P. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307175 · Cited by 427 · cited 4×
“More informa tion about the review team is available in the companion commentary by Woodruff and Sutton (2014).”
BackgroundMethodInfluentialSelf-citationTOXICITY AND TOXICOKINETICS OF PERFLUOROOCTANOIC ACID IN HUMANS AND ANIMALS
KUDO, N., & KAWASHIMA, Y. (2003) · The Journal of Toxicological Sciences · doi:10.2131/jts.28.49 · Cited by 392 · cited 2×
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 20…”
BackgroundScanlon, K., Yip, R., Schieve, L., & Cogswell, M. (2000) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(00)00982-0 · Cited by 367
Halldorsson, T. I., Rytter, D., Haug, L. S., Bech, B. H., Danielsen, I., Becher, G., Henriksen, T. B., & Olsen, S. F. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104034 · Cited by 353 · cited 2×
“Maternal age and gestational age may be correlated with PFOA exposure and fetal growth (Fei et al. 2007; Halldorsson et al. 2012; Ode et al. 2013).”
BackgroundKoustas, E., Lam, J., Sutton, P., Johnson, P. I., Atchley, D. S., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307177 · Cited by 349 · cited 3×
“The results of applying the Navigation Guide method ology to the non human evidence are presented in another review (Koustas et al. 2014), and the results of applying the Navigation Guide methodology to integrate the human and non human evidence streams are presented in a third review (Lam et al.…”
MethodInfluentialSelf-citationPre- and Postnatal Exposure to Perfluorinated Compounds (PFCs)
Fromme, H., Mosch, C., Morovitz, M., Alba‐Alejandre, I., Boehmer, S., Kiranoglu, M., Faber, F. L., Hannibal, I., Genzel‐Boroviczény, O., Koletzko, B. V., et al. (2010) · Environmental Science & Technology · doi:10.1021/es101184f · Cited by 339 · cited 11×
“Only one study that we included in the metaanalysis for birth weight was assigned a high risk of bias for confounding (Fromme et al. 2010).”
BackgroundMethodResultInfluentialHooijmans, C., Tillema, A., Leenaars, M., & Ritskes-Hoitinga, M. (2010) · Laboratory Animals. Journal of the Laboratory Animal Science Association · doi:10.1258/la.2010.009117 · Cited by 333
Relation between maternal haemoglobin concentration and birth weight in different ethnic groups
Steer, P., Alam, M., Wadsworth, J., & Welch, A. (1995) · British medical journal · doi:10.1136/bmj.310.6978.489 · Cited by 333
Good Laboratory Practice: Preventing Introduction of Bias at the Bench
Macleod, M. R., Fisher, M., O'Collins, V., Sena, E. S., Dirnagl, U., Bath, P. M. W., Buchan, A., van der Worp, H. B., Traystman, R., Minematsu, K., et al. (2009) · Stroke · doi:10.1161/strokeaha.108.525386 · Cited by 331
Macleod, M. R., van der Worp, H. B., Sena, E. S., Howells, D. W., Dirnagl, U., & Donnan, G. A. (2008) · Stroke · doi:10.1161/strokeaha.108.515957 · Cited by 319
Serum levels of perfluoroalkyl compounds in human maternal and umbilical cord blood samples
Monroy, R., Morrison, K. M., Teo, K. K., Atkinson, S. A., Kubwabo, C., Stewart, B., & Foster, W. G. (2008) · Environmental Research · doi:10.1016/j.envres.2008.06.001 · Cited by 312 · cited 3×
“Despite these differences, there was evidence of high corre lation of PFOA concentrations between these matrices within the same populations: between cord and maternal serum at birth (Fromme et al. 2010; Kim SK et al. 2011; Monroy et al. 2008); between cord and second or third trimester maternal serum or plasma (Fei…”
BackgroundHooijmans, C. R., Leenaars, M., & Ritskes-Hoitinga, M. J. (2010) · Alternatives to Laboratory Animals · doi:10.1177/026119291003800208 · Cited by 311
Correlations between Prenatal Exposure to Perfluorinated Chemicals and Reduced Fetal Growth
Washino, N., Saijo, Y., Sasaki, S., Kato, S., Ban, S., Konishi, K., Ito, R., Nakata, A., Iwasaki, Y., Saito, K., et al. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.11681 · Cited by 300 · cited 7×
“…et al. 2012 Monroy et al. 2008 Nolan et al. 2009 Savitz et al. 2012a Savitz et al. 2012b (study 1) Savitz et al. 2012b (study 2) Stein et al. 2009 Washino et al. 2009 Whitworth et al. 2012 Re cru itm en t s tra teg y Bli nd ing Co nfo un din g Ex po su re as se ss me nt Inc om ple te ou tco me…”
BackgroundResultInfluentialEndocrine disrupting properties of perfluorooctanoic acid
White, S. S., Fenton, S. E., & Hines, E. P. (2011) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2011.03.011 · Cited by 298 · cited 2×
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 20…”
BackgroundOlsen, G. W., Butenhoff, J. L., & Zobel, L. R. (2009) · Reproductive Toxicology · doi:10.1016/j.reprotox.2009.02.001 · Cited by 293 · cited 2×
“Environmental Health Perspectives • volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 20…”
BackgroundHines, E. P., White, S. S., Stanko, J. P., Gibbs-Flournoy, E. A., Lau, C., & Fenton, S. E. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.02.021 · Cited by 282
DeWitt, J. C., Shnyra, A. A., Badr, M. Z., Loveless, S. E., Hoban, D., Frame, S. R., Cunard, R. A., Anderson, S. E., Meade, B. J., Peden‐Adams, M. M., et al. (2008) · Critical Reviews in Toxicology · doi:10.1080/10408440802209804 · Cited by 274 · cited 1×
“…volume 122 | number 10 | October 2014 1029 there have been inconsistent conclusions about the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 2007; Lindstrom…”
BackgroundAbbott, B. D., Wolf, C. J., Schmid, J., Das, K. P., ZEHR, R. D. J., Helfant, L., Nakayama, S. F., Lindstrom, A. B., Strynar, M. J., & Lau, C. S. (2007) · Toxicological Sciences · doi:10.1093/toxsci/kfm110 · Cited by 271
McPartland, J., Glass, M., & Pertwee, R. (2007) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0707399 · Cited by 266
Midasch, O., Drexler, H., Hart, N., Beckmann, M. W., & Angerer, J. (2007) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-006-0165-9 · Cited by 265
The GRADE approach and Bradford Hill's criteria for causation
Schünemann, H., Hill, S., Guyatt, G., Akl, E. A., & Ahmed, F. (2011) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2010.119933 · Cited by 262
Animal Research: Reporting In Vivo Experiments: The ARRIVE Guidelines
Kilkenny, C., Browne, W., Cuthill, I. C., Emerson, M., & Altman, D. G. (2010) · The Journal of Gene Medicine · doi:10.1002/jgm.1473 · Cited by 256
Emergency medicine animal research: does use of randomization and blinding affect the results?
Bebarta, V., Luyten, D., & Heard, K. (2003) · Academic Emergency Medicine · doi:10.1111/j.1553-2712.2003.tb00056.x · Cited by 244
Kim, S., Choi, K., Ji, K., Seo, J., Kho, Y., Park, J., Kim, S., Park, S., Hwang, I., Jeon, J.-M., et al. (2011) · Environmental Science and Technology · doi:10.1021/es202408a.s001 · Cited by 243 · cited 1×
“The existence of unmeasured confounders will always be possible with observational studies, but we decided to not let this under mine our ability to make a statement about the available data.”
BackgroundWhite, S., Calafat, A., Kuklenyik, Z., Villanueva, L. R., Zehr, R. D., Helfant, L., Strynar, M., Lindstrom, A., Thibodeaux, J. R., Wood, C., et al. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl177 · Cited by 229
Maisonet, M., Terrell, M. L., Mcgeehin, M., Christensen, K., Holmes, A. K., Calafat, A., & Marcus, M. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1003096 · Cited by 228 · cited 10×
“One exception was Maisonet et al. (2012) (see Supplemental Material, Table S13), for which we designated a higher risk of bias for fetal growth measures other than birth weight because of a large amount of missing data for outcomes other than birth weight in that study.”
BackgroundMethodInfluentialDeterminants of Fetal Exposure to Polyfluoroalkyl Compounds in Baltimore, Maryland
Apelberg, B. J., Goldman, L. R., Calafat, A. M., Herbstman, J. B., Kuklenyik, Z., Heidler, J., Needham, L. L., Halden, R. U., & Witter, F. R. (2007) · Environmental Science & Technology · doi:10.1021/es0700911 · Cited by 226 · cited 8×
“Study PFOA increase PFOA range (ng/mL) Covariates Apelberg et al. 2007 ln ng/mL 0.3–7.1 ga Apelberg et al. 2007 ln ng/mL 0.3–7.1 ga, ma, bmi, race, par, smk, sex, ht, wtg, dia, hyp Apelberg et al. 2007 25th to 75th percentile 1.2–2.1 ga Apelberg et al. 2007 25th to 75th percentile 1.2–2.1 ga, ma, bmi, race, par, smk,…”
BackgroundMethodInfluentialLam, J., Koustas, E., Sutton, P., Johnson, P. I., Atchley, D. S., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J. (2014) · Environmental Health Perspectives · doi:10.1289/ehp.1307923 · Cited by 214 · cited 3×
“…of applying the Navigation Guide method ology to the non human evidence are presented in another review (Koustas et al. 2014), and the results of applying the Navigation Guide methodology to integrate the human and non human evidence streams are presented in a third review (Lam et al. 2014).”
BackgroundMethodInfluentialSelf-citationWolf, C. J., Fenton, S., Schmid, J., Calafat, A., Kuklenyik, Z., Bryant, X. A., Thibodeaux, J. R., Das, K., White, S., Lau, C., et al. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfl159 · Cited by 199
Perfluorinated Compounds in Umbilical Cord Blood and Adverse Birth Outcomes
Chen, M.-H., Ha, E., Wen, T.-W., Su, Y.-D., Lien, G., Chen, C.-Y., Chen, P.-C., & Hsieh, W. S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0042474 · Cited by 191 · cited 11×
“These later publica tions (Chen et al. 2012; Maisonet et al. 2012; Whitworth et al. 2012) were included in our metaanalysis, showing consistent results and an overall reduction in birth weight associated with PFOA exposure.”
BackgroundMethodResultInfluentialThe reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat
Butenhoff, J. L., Kennedy, G. L., Frame, S. R., O’Connor, J. C., & York, R. G. (2004) · Toxicology · doi:10.1016/j.tox.2003.11.005 · Cited by 188
Hagenaars, A., Vergauwen, L., Coen, W. D., & Knapen, D. (2010) · Chemosphere · doi:10.1016/j.chemosphere.2010.10.076 · Cited by 188
Sawaya, G. F., Guirguis‐Blake, J., LeFevre, M. L., Harris, R., Petitti, D. B., & for the U.S. Preventive Services Task Force (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-12-200712180-00007 · Cited by 187 · cited 4×
“We used criteria and considerations used by IARC (2006), the U.S. Preventive Services Task Force (Sawaya et al. 2007), and the U.S. EPA (1991, 1996) for the type of evidence considered for each of these strength of evidence categories.”
BackgroundMethodInfluentialBoberg, J., Metzdorff, S., Wortziger, R., Axelstad, M., Brokken, L., Vinggaard, A., Dalgaard, M., & Nellemann, C. (2008) · Toxicology · doi:10.1016/j.tox.2008.05.020 · Cited by 185
Improving the translational hit of experimental treatments in multiple sclerosis
Vesterinen, H. M., Sena, E. S., ffrench-Constant, C., Williams, A., Chandran, S., & Macleod, M. R. (2010) · Multiple Sclerosis Journal · doi:10.1177/1352458510379612 · Cited by 182
Perfluorooctanoic Acid Exposure and Pregnancy Outcome in a Highly Exposed Community
Savitz, D. A., Stein, C. R., Bartell, S. M., Elston, B., Gong, J. F., Shin, H., & Wellenius, G. A. (2012) · Epidemiology · doi:10.1097/ede.0b013e31824cb93b · Cited by 177 · cited 13×
“…ga, bmi, par, smk Nolan et al. 2009 Low to mid exposure NA ga, ga2, ga3, ma, race, sex, SES Nolan et al. 2009 Low to high exposure NA ga, ga2, ga3, ma, race, sex, SES Savitz et al. 2012b, study II 25th to 75th IQR (ln PFOA) 1.92 ga, ma, par, edu, smk, exposyr, state Savitz et al. 2012b, study II…”
BackgroundMethodResultInfluentialFetal growth indicators and perfluorinated chemicals: a study in the Danish National Birth Cohort.
Fei, C.-Y., Mclaughlin, J., Tarone, R., & Olsen, J. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn095 · Cited by 168 · cited 3×
“The Fei et al. study (2007) was the only study that was included in the meta-analysis and was assigned “high” risk of bias for “conflict of interest.”
BackgroundMethodKim, S., Lee, K. T., Kang, C. S., Tao, L., Kannan, K., Kim, K., Kim, C.-K., Lee, J. S., Park, P. S., Yoo, Y. W., et al. (2010) · Environmental Pollution · doi:10.1016/j.envpol.2010.09.008 · Cited by 161
Krauth, D., Woodruff, T. J., & Bero, L. A. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1206389 · Cited by 154 · cited 2×
“We also included the funding source and declared conflicts of interest as a potential source of bias based on empirical data from studies conducted on phar macological treatments that reported evidence of bias associated with funding source (Krauth et al. 2013; Lundh et al. 2012).”
MethodSelf-citationPrenatal Exposure to PFOS or PFOA Alters Motor Function in Mice in a Sex-Related Manner
Onishchenko, N., Fischer, C., Ibrahim, W. N. W., Negri, S., Spulber, S., Cottica, D., & Ceccatelli, S. (2011) · Neurotoxicity research · doi:10.1007/s12640-010-9200-4 · Cited by 152
Maternal exposure to perfluorinated acids and fetal growth
Hamm, M. P., Cherry, N. M., Chan, E., Martin, J. W., & Burstyn, I. (2010) · Journal of Exposure Science & Environmental Epidemiology · doi:10.1038/jes.2009.57 · Cited by 151 · cited 9×
“…None Hamm et al. 2010 ln ng/mL < LOD–18 ga, ma, race, grav, mwt, matht, smk, sex Hamm et al. 2010 ng/mL < LOD–18 ga, ma, race, grav, mwt, matht, smk, sex Hamm et al. 2010 1st to 2nd tertile (ng/mL) < LOD– < 1.1 to 1.1–2.1 ga, ma, race, grav, mwt, matht, smk, sex Hamm et al. 2010 1st to 3rd…”
BackgroundMethodResultInfluentialReporting of conflicts of interest in meta-analyses of trials of pharmacological treatments
Roseman, M. (2011) · JAMA · doi:10.1001/jama.2011.257 · Cited by 145
Developmental Origins of Health and Disease: List of contributors
Gluckman, P., & Hanson, M. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511544699 · Cited by 142
White, S., Stanko, J., Kato, K., Calafat, A., Hines, E., & Fenton, S. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1002741 · Cited by 138 · cited 1×
“…the evidence of an association between PFOA and fetal growth (DeWitt et al. 2009; Hekster et al. 2003; Jensen and Leffers 2008; Kennedy et al. 2004; Kudo and Kawashima 2003; Lau et al. 2004, 2007; Lindstrom et al. 2011; Olsen et al. 2009; Post et al. 2012; Steenland et al. 2010; White et al. 2011).”
BackgroundWoodruff, T. J., Sutton, P., & The Navigation Guide Work Group (2011) · Health Affairs · doi:10.1377/hlthaff.2010.1219 · Cited by 134
Self-citationThe effect of prenatal perfluorinated chemicals exposures on pediatric atopy
Wang, I., Hsieh, W., Chen, C., Fletcher, T., Lien, G., Chiang, H., Chiang, C., Wu, T.-N., & Chen, P. (2011) · Environmental Research · doi:10.1016/j.envres.2011.04.006 · Cited by 128 · cited 2×
“In addition, by contacting authors of one of the included studies (Wang et al. 2011), we were alerted to an additional study on the same cohort under review at the time (Chen et al. 2012) and were able to include that study in the metaanalysis.”
BackgroundSavitz, D. A., Stein, C. R., Elston, B., Wellenius, G. A., Bartell, S. M., Shin, H., Vieira, V. M., & Fletcher, T. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104752 · Cited by 121 · cited 12×
“…ga, bmi, par, smk Nolan et al. 2009 Low to mid exposure NA ga, ga2, ga3, ma, race, sex, SES Nolan et al. 2009 Low to high exposure NA ga, ga2, ga3, ma, race, sex, SES Savitz et al. 2012b, study II 25th to 75th IQR (ln PFOA) 1.92 ga, ma, par, edu, smk, exposyr, state Savitz et al. 2012b, study II…”
BackgroundMethodResultInfluentialPerfluorinated compounds in relation to birth weight in the Norwegian Mother and Child Cohort Study.
Whitworth, K. W., Haug, L., Baird, D., Becher, G., Hoppin, J., Skjærven, R., Thomsen, C., Eggesbø, M., Travlos, G., Wilson, R., et al. (2012) · American Journal of Epidemiology · doi:10.1093/aje/kwr459 · Cited by 112 · cited 12×
“…2009 ng/mL ND–5.3 ma, ga Whitworth et al. 2012 ng/mL median (IQR) = 2.2(1.6–3.0) ga, ma, bmi, par Whitworth et al. 2012 1st to 2nd quartile < 1.65 to 1.65–2.24 ga, ma, bmi, par Whitworth et al. 2012 1st to 3rd quartile < 1.65 to 2.25–3.03 ga, ma, bmi, par Whitworth et al. 2012 1st to 4th…”
BackgroundResultInfluentialPerfluorooctanoate: Placental and lactational transport pharmacokinetics in rats.
Hinderliter, P., Mylchreest, E., Gannon, S. A., Butenhoff, J., & Kennedy, G. (2005) · Toxicology · doi:10.1016/j.tox.2005.03.010 · Cited by 101
Nolan, L. A., Nolan, J. M., Shofer, F., Rodway, N., & Emmett, E. (2008) · Reproductive Toxicology · doi:10.1016/j.reprotox.2008.11.001 · Cited by 96 · cited 1×
“Maternal age and gestational age may be correlated with PFOA exposure and fetal growth (Fei et al. 2007; Halldorsson et al. 2012; Ode et al. 2013).”
BackgroundDeterminants of maternal and fetal exposure and temporal trends of perfluorinated compounds
Ode, A., Rylander, L., Lindh, C. H., Källén, K., Jönsson, B., Gustafsson, P., Olofsson, P., Ivarsson, S. A., & Rignell‐Hydbom, A. (2013) · Environmental Science and Pollution Research · doi:10.1007/s11356-013-1573-5 · Cited by 90 · cited 1×
“Maternal age and gestational age may be correlated with PFOA exposure and fetal growth (Fei et al. 2007; Halldorsson et al. 2012; Ode et al. 2013).”
BackgroundWhite, S., Kato, K., Jia, L. T., Basden, B. J., Calafat, A., Hines, E., Stanko, J., Wolf, C. J., Abbott, B., & Fenton, S. (2008) · Reproductive Toxicology · doi:10.1016/j.reprotox.2008.11.054 · Cited by 88
Fenton, S., Reiner, J. L., Nakayama, S., Delinsky, A. D., Stanko, J., Hines, E., White, S., Lindstrom, A., Strynar, M., & Petropoulou, S.-S. E. (2009) · Reproductive Toxicology · doi:10.1016/j.reprotox.2009.02.012 · Cited by 80
Umbilical cord blood levels of perfluoroalkyl acids and polybrominated flame retardants
Arbuckle, T. E., Kubwabo, C., WALKER, M. C., Davis, K. A., Lalonde, K., Kosarac, I., Wen, S. W., & Arnold, D. L. (2012) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2012.03.004 · Cited by 78
Perfluorooctanoic acid induces developmental cardiotoxicity in chicken embryos and hatchlings
Jiang, Q., Lust, R. M., Strynar, M. J., Dagnino, S., & DeWitt, J. C. (2012) · Toxicology · doi:10.1016/j.tox.2012.01.005 · Cited by 69
DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE
Gilbert-Barness, E. F. (2007) · Fetal and Pediatric Pathology · doi:10.1080/15513810701394736 · Cited by 68
Effects of perfluorooctanoic acid (PFOA) exposure to pregnant mice on reproduction.
Yahia, D., el-Nasser, M. A., Abedel-Latif, M., Tsukuba, C., Yoshida, M., Sato, I., & Tsuda, S. (2010) · Journal of Toxicological Sciences · doi:10.2131/jts.35.527 · Cited by 67
Beronius, A., Molander, L., Rudén, C., & Hanberg, A. (2014) · Journal of Applied Toxicology · doi:10.1002/jat.2991 · Cited by 64
Forest Plot Viewer: a new graphing tool.
Boyles, A., Harris, S. F., Rooney, A. A., & Thayer, K. (2011) · Epidemiology · doi:10.1097/ede.0b013e318225ba48 · Cited by 60
Spachmo, B., & Arukwe, A. (2011) · Aquatic Toxicology · doi:10.1016/j.aquatox.2011.07.018 · Cited by 59
Preclinical studies of human disease: Time to take methodological quality seriously
van der Worp, H. B., & Macleod, M. R. (2011) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2011.04.008 · Cited by 58
Guest Editorial: Biomarkers of Perfluorinated Chemicals and Birth Weight
Savitz, D. (2007) · Environmental Health Perspectives · doi:10.1289/ehp.10923 · Cited by 50
Neurobehavioral Teratogenicity of Perfluorinated Alkyls in an Avian Model
Pinkas, A., Slotkin, T. A., Brick-Turin, Y., Van der Zee, E. A., & Yanai, J. (2010) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2009.11.004 · Cited by 48
Staples, R. E., Burgess, B. A., & Kerns, W. (1984) · Fundamental and Applied Toxicology · doi:10.1016/0272-0590(84)90200-8 · Cited by 44
O'Brien, J., Crump, D., Mundy, L. J., Chu, S.-G., McLaren, K., Vongphachan, V., Letcher, R., & Kennedy, S. (2009) · Toxicology Letters · doi:10.1016/j.toxlet.2009.07.004 · Cited by 43
Bellinger, D. (2012) · Neurotoxicology · doi:10.1016/j.neuro.2012.04.003 · Cited by 36
York, R. G., Kennedy, G. L., Olsen, G. W., & Butenhoff, J. L. (2010) · Toxicology · doi:10.1016/j.tox.2010.03.005 · Cited by 27
Evidence-based translational medicine.
Howells, D., & Macleod, M. (2013) · Stroke · doi:10.1161/strokeaha.113.000469 · Cited by 26
Vesterinen, H. V., Egan, K. J., Deister, A., Schlattmann, P., Macleod, M., & Dirnagl, U. (2011) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2010.232 · Cited by 19
Disturbance of perfluorooctanoic acid on development and behavior in Drosophila larvae
Wang, J.-S., Li, Y., Liu, Y., Zhang, H., & Dai, J. (2010) · Environmental Toxicology and Chemistry · doi:10.1002/etc.237 · Cited by 19
Are developmentally exposed C57BL/6 mice insensitive to suppression of TDAR by PFOA?
Hu, Q., Strynar, M., & DeWitt, J. (2010) · Journal of Immunotoxicology · doi:10.3109/1547691x.2010.520045 · Cited by 13
Flagged first, then by citations
20 of the 131 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Higgins JPT, Deeks JJ. 2011. Chapter 7: Selecting studies and collecting data. In: Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0 (Higgins JPT, Green S, eds).Available: http://handbook.cochrane.org/chapter_7/7_selecting_studies_and_collecting_data.htm [accessed 29 August 2014].
- Stein, 2009, Serum levels of perfluorooctanoic acid and perfluorooctane sulfonate and pregnancy outcome., Am J Epidemiol, 170, 837, 10.1093/aje/kwp212 · DOI
Cited by
Sorted by citations
SYRCLE’s risk of bias tool for animal studies
Hooijmans, C. R., Rovers, M. M., de Vries, R. B., Leenaars, M., Ritskes-Hoitinga, M., & Langendam, M. W. (2014) · BMC Medical Research Methodology · doi:10.1186/1471-2288-14-43 · Cited by 4,415
Fenton, S. E., Ducatman, A., Boobis, A., DeWitt, J. C., Lau, C., Ng, C., Smith, J. S., & Roberts, S. M. (2020) · Environmental Toxicology and Chemistry · doi:10.1002/etc.4890 · Cited by 2,445
“The authors noted similarities in experimental studies (Johnson et al. 2014; Koustas et al. 2014) and concluded that there was “sufficient” human and corroborative toxicology evidence of a detrimental effect of PFOA on birth weight (Johnson et al. 2014; Koustas et al. 2014; Lam et al. 2014).”
BackgroundResultEDC-2: the endocrine society's second scientific statement on endocrine-disrupting chemicals
Gore, A. C., Chappell, V. A., Fenton, S. E., Flaws, J. A., Nadal, A., Prins, G. S., Toppari, J., & Zoeller, R. T. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1010 · Cited by 2,407
Morgan, R. L., Whaley, P., Thayer, K. A., & Schünemann, H. J. (2018) · Environment International · doi:10.1016/j.envint.2018.07.015 · Cited by 1,424
Risk to human health related to the presence of perfluoroalkyl substances in food
Panel), E. P. O. C. I. T. F. C. (. C., Schrenk, D., Bignami, M., Bodin, L., Chipman, J. K., del Mazo, J., Grasl‐Kraupp, B., Hogstrand, C., Hoogenboom, L. (., Leblanc, J., et al. (2020) · EFSA Journal · doi:10.2903/j.efsa.2020.6223 · Cited by 989
Metadata
- Authors
- Johnson, P. I., Sutton, P., Atchley, D. S., Koustas, E., Lam, J., Sen, S., Robinson, K. A., Axelrad, D. A., & Woodruff, T. J.
- Affiliations
- University of California, San Francisco (US)
- Environmental Protection Agency (US)
- Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA
- Johns Hopkins University (US)
- Corresponding author
- Johnson, Paula I.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-06-25
- Volume
- 122
- Issue
- 10
- Pages
- 1028-1039
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- PMC
- PMC4181929
- OpenAlex
- W4243002209
- Cited by
- 449
- References
- 131
- Citations by year
- 2026: 29 · 2025: 31 · 2024: 36 · 2023: 43 · 2022: 32 · 2021: 50 · 2020: 68 · 2019: 34 · 2018: 31 · 2017: 42 · 2016: 25 · 2015: 20 · 2014: 8
- FWCI
- 2.88
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- public-domain
- creativecommons.org/licenses/by/4.0/ (vor, 1283 d)
- Locations
- Environmental Health Perspectives (publishedVersion, public-domain)
- PubMed Central (publishedVersion, public-domain)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- U.S. Department of Energy
- U.S. Environmental Protection Agency (RD-83543301)
- New York Community Trust
- Heinz Endowments
- Johnson Family Foundation
- Rose Foundation for Communities and the Environment
- Kaiser Permanente
- Office of Research and Development
- Oak Ridge Institute for Science and Education
- University of California, San Francisco
- National Center For Environmental Assessment
- National Institute of Environmental Health Sciences (ES018135, P01ES022841, ES022841, P20ES018135)
- Topics
- Physical Sciences › Environmental Science › Environmental Chemistry › Per- and polyfluoroalkyl substances research
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Health, Environment, Cognitive Aging
- Keywords
- perfluorooctanoic acid, fetal growth, birth weight, early life exposure, environmental health, risk of bias, perfluorinated compounds
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
