The Chronic Inflammatory Hypothesis for the Morbidity Associated with Morbid Obesity: Implications and Effects of Weight Loss

Acute-Phase Proteins and Other Systemic Responses to Inflammation

Gabay, C., & Kushner, I. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902113400607 · Cited by 6,734

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women

Ridker, P. M., Hennekens, C. H., Buring, J. E., & Rifai, N. (2000) · New England Journal of Medicine · doi:10.1056/nejm200003233421202 · Cited by 5,850

Elevated C-reactive protein levels in overweight and obese adults

Visser, M. (1999) · JAMA · doi:10.1001/jama.282.22.2131 · Cited by 2,494

C-Reactive Protein in Healthy Subjects: Associations With Obesity, Insulin Resistance, and Endothelial Dysfunction: A Potential Role for Cytokines Originating From Adipose Tissue?

Yudkin, J. S., Stehouwer, C. D. A., Emeis, J. J., & Coppack, S. W. (1999) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.19.4.972 · Cited by 2,465

The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina

Liuzzo, G., Biasucci, L. M., Gallimore, J. R., Grillo, R. L., Rebuzzi, A. G., Pepys, M. B., & Maseri, A. (1994) · New England Journal of Medicine · doi:10.1056/nejm199408183310701 · Cited by 2,354

Protection from obesity-induced insulin resistance in mice lacking TNF-α function

Uysal, K. T., Wiesbrock, S. M., Marino, M. W., & Hotamisligil, G. S. (1997) · Nature · doi:10.1038/39335 · Cited by 2,234

C-Reactive Protein, a Sensitive Marker of Inflammation, Predicts Future Risk of Coronary Heart Disease in Initially Healthy Middle-Aged Men

Köenig, W., Sund, M., Fröhlich, M., Fischer, H.-G., Löwel, H., Döring, A., Hutchinson, W. L., & Pepys, M. B. (1999) · Circulation · doi:10.1161/01.cir.99.2.237 · Cited by 1,952

Annual Deaths Attributable to Obesity in the United States

Allison, D. B. (1999) · JAMA · doi:10.1001/jama.282.16.1530 · Cited by 1,863

Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?

Yudkin, J. S., Kumari, M., Humphries, S. E., & Mohamed-Ali, V. (2000) · Atherosclerosis · doi:10.1016/s0021-9150(99)00463-3 · Cited by 1,775

Prospective Study of C-Reactive Protein and the Risk of Future Cardiovascular Events Among Apparently Healthy Women

Ridker, P. M., Buring, J. E., Shih, J., Matias, M., & Hennekens, C. H. (1998) · Circulation · doi:10.1161/01.cir.98.8.731 · Cited by 1,642

Adipose tissue, adipokines, and inflammation

Fantuzzi, G. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.02.023 · Cited by 2,606

Adipose Tissue, Inflammation, and Cardiovascular Disease

Berg, A. H., & Scherer, P. E. (2005) · Circulation Research · doi:10.1161/01.res.0000163635.62927.34 · Cited by 2,113

Recent advances in the relationship between obesity, inflammation, and insulin resistance.

Bastard, J., Maachi, M., Lagathu, C., Kim, M. J., Caron, M., Vidal, H., Capeau, J., & Fève, B. (2006) · PubMed · Cited by 2,090

Reduction of Macrophage Infiltration and Chemoattractant Gene Expression Changes in White Adipose Tissue of Morbidly Obese Subjects After Surgery-Induced Weight Loss

Cancello, R., Henegar, C., Viguerie, N., Taleb, S., Poitou, C., Rouault, C., Coupaye, M., Pelloux, V., Hugol, D., Bouillot, J.-L., et al. (2005) · Diabetes · doi:10.2337/diabetes.54.8.2277 · Cited by 1,164

Higher Inflammatory Marker Levels in Older Persons: Associations With 5-Year Change in Muscle Mass and Muscle Strength

Schaap, L. A., Pluijm, S. M. F., Deeg, D. J. H., Harris, T. B., Kritchevsky, S. B., Newman, A. B., Colbert, L. H., Pahor, M., Rubin, S. M., Tylavsky, F. A., et al. (2009) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glp097 · Cited by 683

Release of Interleukins and Other Inflammatory Cytokines by Human Adipose Tissue Is Enhanced in Obesity and Primarily due to the Nonfat Cells

Fain, J. N. (2006) · Vitamins and hormones · doi:10.1016/s0083-6729(06)74018-3 · Cited by 702

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

Henegar, C., Tordjman, J., Achard, V., Lacasa, D., Cremer, I., Guerre-Millo, M., Poitou, C., Basdevant, A., Stich, V., Viguerie, N., et al. (2008) · Genome Biology · doi:10.1186/gb-2008-9-1-r14 · Cited by 471

Obesity and Surgical Wound Healing: A Current Review

Pierpont, Y. N., Dinh, T. P., Salas, R., Johnson, E. L., Wright, T. G., Robson, M. C., & Payne, W. G. (2014) · ISRN Obesity · doi:10.1155/2014/638936 · Cited by 480

Association between Class III Obesity (BMI of 40–59 kg/m2) and Mortality: A Pooled Analysis of 20 Prospective Studies

Kitahara, C. M., Flint, A. J., de González, A. B., Bernstein, L., Brotzman, M. J., MacInnis, R. J., Moore, S. C., Robien, K., Rosenberg, P. S., Singh, P. N., et al. (2014) · PLoS Medicine · doi:10.1371/journal.pmed.1001673 · Cited by 428

Chemerin: at the crossroads of inflammation and obesity

Ernst, M. C., & Sinal, C. J. (2010) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2010.08.001 · Cited by 431

Exercise-Induced Changes in Visceral Adipose Tissue Mass Are Regulated by IL-6 Signaling: A Randomized Controlled Trial

Wedell-Neergaard, A.-S., Lang Lehrskov, L., Christensen, R. H., Legaard, G. E., Dorph, E., Larsen, M. K., Launbo, N., Fagerlind, S. R., Seide, S. K., Nymand, S., et al. (2019) · Cell Metabolism · doi:10.1016/j.cmet.2018.12.007 · Cited by 403

Relation of body mass index to cancer risk in 362,552 Swedish men

Samanic, C. M., Chow, W.-H., Gridley, G., Järvholm, B., & Fraumeni, J. F. (2006) · Cancer Causes & Control · doi:10.1007/s10552-006-0023-9 · Cited by 385

Obesity and inflammation: the effects of weight loss

Forsythe, L. K., Wallace, J. M. W., & Livingstone, M. B. E. (2008) · Nutrition Research Reviews · doi:10.1017/s0954422408138732 · Cited by 381

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

Cheng, L., Wang, J., Dai, H., Duan, Y., An, Y., Shi, L., Lv, Y., Li, H., Wang, C., Ma, Q., et al. (2021) · Adipocyte · doi:10.1080/21623945.2020.1870060 · Cited by 404

Contribution of Adipose Tissue Inflammation to the Development of Type 2 Diabetes Mellitus

Burhans, M. S., Hagman, D. K., Kuzma, J. N., Schmidt, K. A., & Kratz, M. (2018) · Comprehensive physiology · doi:10.1002/cphy.c170040 · Cited by 461

Macrophage-Secreted Factors Impair Human Adipogenesis: Involvement of Proinflammatory State in Preadipocytes

Lacasa, D., Taleb, S., Keophiphath, M., Miranville, A., & Clement, K. (2007) · Endocrinology · doi:10.1210/en.2006-0687 · Cited by 334

Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats

Boitard, C., Cavaroc, A., Sauvant, J., Aubert, A., Castanon, N., Layé, S., & Ferreira, G. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.03.005 · Cited by 324

The burden of obesity on infectious disease

Karlsson, E. A., & Beck, M. A. (2010) · Experimental Biology and Medicine · doi:10.1258/ebm.2010.010227 · Cited by 296

Inflammatory lipid mediators in adipocyte function and obesity

Iyer, A., Fairlie, D. P., Prins, J. B., Hammock, B. D., & Brown, L. (2010) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2009.264 · Cited by 290

Obesity and Inflammation: Change in Adiponectin, C-Reactive Protein, Tumour Necrosis Factor-Alpha and Interleukin-6 After Bariatric Surgery

Illán-Gómez, F., Gonzálvez-Ortega, M., Orea-Soler, I., Alcaraz-Tafalla, M. S., Aragón-Alonso, A., Pascual-Díaz, M., Pérez-Paredes, M., & Lozano-Almela, M. L. (2012) · Obesity Surgery · doi:10.1007/s11695-012-0643-y · Cited by 265

Neutrophil Activation in Morbid Obesity, Chronic Activation of Acute Inflammation

Nijhuis, J., Rensen, S. S., Slaats, Y., van Dielen, F. M. H., Buurman, W. A., & Greve, J. W. M. (2009) · Obesity · doi:10.1038/oby.2009.113 · Cited by 272

The Obesity Pandemic: Where Have We Been and Where Are We Going?

Roth, J., Qiang, X., Marbán, S. L., Redelt, H., & Lowell, B. (2004) · Obesity Research · doi:10.1038/oby.2004.273 · Cited by 267

Role of macrophage tissue infiltration in metabolic diseases

Bouloumié, A., Curat, C. A., Sengenès, C., Lolmède, K., Miranville, A., & Busse, R. (2005) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/01.mco.0000172571.41149.52 · Cited by 268

The correlation between adiposity and adiponectin, tumor necrosis factor α, interleukin-6 and high sensitivity C-reactive protein levels. Is adipocyte size associated with inflammation in adults?

Bahçeci, M., Gökalp, D., Bahçeci, S., Tuzcu, A. K., Atmaca, S., & Arikan, S. (2007) · Journal of Endocrinological Investigation · doi:10.1007/bf03347427 · Cited by 266

Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes

Gonzales, A. M., & Orlando, R. A. (2008) · Nutrition & Metabolism · doi:10.1186/1743-7075-5-17 · Cited by 260

The adipocyte as an active participant in energy balance and metabolism

Badman, M. K., & Flier, J. S. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.03.058 · Cited by 256

Impact of Body Weight and Extreme Obesity on the Presentation, Treatment, and In-Hospital Outcomes of 50,149 Patients With ST-Segment Elevation Myocardial Infarction

Das, S. R., Alexander, K. P., Chen, A. Y., Powell‐Wiley, T. M., Diercks, D. B., Peterson, E. D., Roe, M. T., & de Lemos, J. A. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.09.030 · Cited by 249

Signaling Specificity of Interleukin-6 Action on Glucose and Lipid Metabolism in Skeletal Muscle

Al-Khalili, L., Bouzakri, K., Glund, S., Lönnqvist, F., Koistinen, H. A., & Krook, A. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0490 · Cited by 250

Serum Levels of Interleukin‐6 and C‐Reactive Protein Correlate With Body Mass Index Across the Broad Range of Obesity

Khaodhiar, L., Ling, P., Blackburn, G. L., & Bistrian, B. R. (2004) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607104028006410 · Cited by 243

One-Anastomosis Gastric Bypass by Laparoscopy: Results of the First 209 Patients

Carbajo, M., García-Caballero, M., Toledano, M., Osorio, D., García-Lanza, C., & Carmona, J. A. L. (2005) · Obesity Surgery · doi:10.1381/0960892053576677 · Cited by 233

CCL5 Promotes Macrophage Recruitment and Survival in Human Adipose Tissue

Kéophiphath, M., Rouault, C., Divoux, A., Clément, K., & Lacasa, D. (2009) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.109.197442 · Cited by 244

The hematologic consequences of obesity

Purdy, J. C., & Shatzel, J. J. (2021) · European Journal Of Haematology · doi:10.1111/ejh.13560 · Cited by 227

The role of interleukin‐6 in insulin resistance, body fat distribution and energy balance

Hoene, M., & Weigert, C. (2007) · Obesity Reviews · doi:10.1111/j.1467-789x.2007.00410.x · Cited by 226

Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance

Poher, A.-L., Altirriba, J., Veyrat‐Durebex, C., & Rohner‐Jeanrenaud, F. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00004 · Cited by 219

Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions

Beilharz, J. E., Maniam, J., & Morris, M. J. (2015) · Nutrients · doi:10.3390/nu7085307 · Cited by 214

Proinflammatory Cytokines in Obesity: Impact of Type 2 Diabetes Mellitus and Gastric Bypass

Catalán, V., Gómez‐Ambrosi, J., Ramírez, B., Rotellar, F., Pastor, C., Silva, C., Rodríguez, A., Gil, M. J., Cienfuegos, J. A., & Frühbeck, G. (2007) · Obesity Surgery · doi:10.1007/s11695-008-9424-z · Cited by 212

Maternal obesity and markers of inflammation in pregnancy

Madan, J. C., Davis, J. M., Craig, W. Y., Collins, M. F., Allan, W. C., Quinn, R., & Dammann, O. (2009) · Cytokine · doi:10.1016/j.cyto.2009.05.004 · Cited by 205

Curcumin and obesity: evidence and mechanisms

Alappat, L., & Awad, A. B. (2010) · Nutrition Reviews · doi:10.1111/j.1753-4887.2010.00341.x · Cited by 198

Obesity, metabolic syndrome and sleep apnoea: all pro‐inflammatory states

Alam, I., Lewis, K. E., Stephens, J. W., & BAXTER, J. N. (2006) · Obesity Reviews · doi:10.1111/j.1467-789x.2006.00269.x · Cited by 192

Effect of caloric restriction on gut permeability, inflammation markers, and fecal microbiota in obese women

Ott, B., Skurk, T., Hastreiter, L., Lagkouvardos, I., Fischer, S., Büttner, J., Kellerer, T., Clavel, T., Rychlik, M., Haller, D., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-12109-9 · Cited by 170

Disruption of the Chemokine-Like Receptor-1 (CMKLR1) Gene Is Associated with Reduced Adiposity and Glucose Intolerance

Ernst, M. C., Haidl, I. D., Zuniga, L. A., Dranse, H. J., Rourke, J. L., Zabel, B. A., Butcher, E. C., & Sinal, C. J. (2011) · Endocrinology · doi:10.1210/en.2011-1490 · Cited by 171

Challenging homeostasis to define biomarkers for nutrition related health

van Ommen, B., Keijer, J., Heil, S. G., & Kaput, J. (2009) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200800390 · Cited by 167

Defective Leptin/Leptin Receptor Signaling Improves Regulatory T Cell Immune Response and Protects Mice From Atherosclerosis

Taleb, S., Herbin, O., Ait‐Oufella, H., Verreth, W., Gourdy, P., Barateau, V., Merval, R., Esposito, B., Clément, K., Holvoet, P., et al. (2007) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.107.149567 · Cited by 157

Mechanisms linking obesity and cancer

Louie, S. M., Roberts, L. S., & Nomura, D. K. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2013.02.008 · Cited by 152

Effect of body mass index on the outcome of infections: a systematic review

Falagas, M. E., Athanasoulia, A. P., Peppas, G., & Karageorgopoulos, D. E. (2009) · Obesity Reviews · doi:10.1111/j.1467-789x.2008.00546.x · Cited by 140

Inflammatory Stress and Idiosyncratic Hepatotoxicity: Hints from Animal Models

Deng, X., Luyendyk, J. P., Ganey, P. E., & Roth, R. A. (2009) · Pharmacological Reviews · doi:10.1124/pr.109.001727 · Cited by 139

Calcium and 1,25‐Dihydroxyvitamin D3 Regulation of Adipokine Expression

Sun, X., & Zemel, M. B. (2007) · Obesity · doi:10.1038/oby.2007.540 · Cited by 137

Mechanistic simulations of inflammation: Current state and future prospects

Yoram Vodovotz, B., Constantine, G. M., Rubin, J. E., CSETE, M. E., Voit, E. O., & An, G. C. (2008) · Mathematical Biosciences · doi:10.1016/j.mbs.2008.07.013 · Cited by 135

Obesity-related cognitive impairment: The role of endothelial dysfunction

Buie, J. N. J., Watson, L. S., Smith, C. J., & Sims‐Robinson, C. (2019) · Neurobiology of Disease · doi:10.1016/j.nbd.2019.104580 · Cited by 138

Green tea polyphenols decrease weight gain, ameliorate alteration of gut microbiota, and mitigate intestinal inflammation in canines with high-fat-diet-induced obesity

Li, Y., Rahman, S. U., Huang, Y., Zhang, Y., Ming, P., Zhu, L., Chu, X., Li, J., Feng, S., Wang, X., et al. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.108324 · Cited by 131

Serial changes in inflammatory biomarkers after Roux-en-Y gastric bypass surgery

Miller, G. D., Nicklas, B. J., & Fernandez, A. (2011) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2011.03.006 · Cited by 131

Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects

Solini, A., Santini, E., & Ferrannini, E. (2006) · International Journal of Obesity · doi:10.1038/sj.ijo.0803265 · Cited by 130

Green Tea Polyphenols Reduce Body Weight in Rats by Modulating Obesity-Related Genes

Lu, C., Zhu, W., Shen, C., & Gao, W. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038332 · Cited by 126

Anemia After Bariatric Surgery: More Than Just Iron Deficiency

von Drygalski, A., & Andris, D. A. (2009) · Nutrition in Clinical Practice · doi:10.1177/0884533609332174 · Cited by 123

Increased Serum Amyloid A Concentrations in Morbid Obesity Decrease after Gastric Bypass

Gómez-Ambrosi, J., Salvador, J., Rotellar, F., Silva, C., Catalán, V., Rodríguez, A., Jesús Gil, M., & Frühbeck, G. (2006) · Obesity Surgery · doi:10.1381/096089206776116525 · Cited by 119

Association of IL10 and Other immune response‐ and obesity‐related genes with prostate cancer in CLUE II

Wang, M., Helzlsouer, K. J., Smith, M. W., Hoffman–Bolton, J., Clipp, S. L., Grinberg, V. B., Marzo, A. M. D., Isaacs, W. B., Drake, C. G., Shugart, Y. Y., et al. (2009) · The Prostate · doi:10.1002/pros.20933 · Cited by 120

Roles of Chemokine Ligand-2 (CXCL2) and Neutrophils in Influencing Endothelial Cell Function and Inflammation of Human Adipose Tissue

Rouault, C., Pellegrinelli, V., Schilch, R., Cotillard, A., Poitou, C., Tordjman, J., Sell, H., Clément, K., & Lacasa, D. (2013) · Endocrinology · doi:10.1210/en.2012-1415 · Cited by 119

The effect of bariatric surgery on adipocytokines, renal parameters and other cardiovascular risk factors in severe and very severe obesity: 1-year follow-up

Serra, A., Granada, M. L., Romero, R., Bayés, B., Cantón, A., Bonet, J., Rull, M., Alastrue, A., & Formiguera, X. (2006) · Clinical Nutrition · doi:10.1016/j.clnu.2005.11.014 · Cited by 119

Cardiorespiratory fitness and the metabolic syndrome: Roles of inflammation and abdominal obesity

Wedell‐Neergaard, A., Krogh‐Madsen, R., Petersen, G. L., Hansen, Å. M., Pedersen, B. K., Lund, R., & Brüünsgaard, H. (2018) · PLoS ONE · doi:10.1371/journal.pone.0194991 · Cited by 122

Quercetin attenuates inflammation in human macrophages and adipocytes exposed to macrophage-conditioned media

Overman, A., Chuang, C.-C., & McIntosh, M. (2011) · International Journal of Obesity · doi:10.1038/ijo.2010.272 · Cited by 112

Effects of mode and intensity on the acute exercise-induced IL-6 and CRP responses in a sedentary, overweight population

Mendham, A. E., Donges, C. E., Liberts, E. A., & Duffield, R. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1724-z · Cited by 117

Genetic and Environmental Interactions in Obesity and Type 2 Diabetes

Romao, I., & Roth, J. (2008) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2008.01.022 · Cited by 114

Adipose tissue, inflammation and cardiovascular disease

Ikeoka, D., Mader, J. K., & Pieber, T. R. (2010) · Revista da Associação Médica Brasileira · doi:10.1590/s0104-42302010000100026 · Cited by 110

Adipose Tissue Inflammation and Adiponectin Resistance in Patients With Advanced Heart Failure

Khan, R. S., Kato, T., Chokshi, A. D., Chew, M., Yu, S., Wu, C. C. N., Singh, P., Cheema, F. H., Takayama, H., Harris, C. R., et al. (2012) · Circulation Heart Failure · doi:10.1161/circheartfailure.111.964031 · Cited by 109

A Comprehensive Approach to Evaluate Nutritional Status in Crohn's Patients in the Era of Biologic Therapy: A Case-Control Study

Guerreiro, C. S., Cravo, M. L., Costa, A. R., Miranda, A., Tavares, L., Moura-Santos, P., Marques-Vidal, P. M., & Leitão, C. N. (2007) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2007.01439.x · Cited by 105

Serum Amyloid A: A Marker of Adiposity‐induced Low‐grade Inflammation but Not of Metabolic Status

Poitou, C., Coussieu, C., Rouault, C., Coupaye, M., Cancello, R., Bedel, J., Gouillon, M., Bouillot, J., Oppert, J., Basdevant, A., et al. (2006) · Obesity · doi:10.1038/oby.2006.40 · Cited by 105

Clinical trial: a nutritional supplement Viusid, in combination with diet and exercise, in patients with nonalcoholic fatty liver disease

VILAR GOMEZ, E., RODRIGUEZ DE MIRANDA, A., GRA ORAMAS, B., ARUS SOLER, E., LLANIO NAVARRO, R., CALZADILLA BERTOT, L., YASELLS GARCIA, A., & DEL ROSARIO ABREU VAZQUEZ, M. (2009) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2009.04122.x · Cited by 105

Obesity and malnutrition similarly alter the renin–angiotensin system and inflammation in mice and human adipose

Pinheiro, T. D. A., Barcala-Jorge, A. S., Andrade, J. M. O., Pinheiro, T. D. A., Ferreira, E. C. N., Crespo, T. S., Batista-Jorge, G. C., Vieira, C. A., Lelis, D. D. F., Paraíso, A. F., et al. (2017) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2017.06.008 · Cited by 103

A Western Diet Increases Serotonin Availability in Rat Small Intestine

Bertrand, R. L., Senadheera, S. N., Markus, I., Liu, L., Howitt, L., Chen, H., Murphy, T. V., Sandow, S. L., & Bertrand, P. P. (2010) · Endocrinology · doi:10.1210/en.2010-0377 · Cited by 100

Mechanism of ER Stress and Inflammation for Hepatic Insulin Resistance in Obesity

Kim, O., Jun, W., & Lee, J. (2015) · Annals of Nutrition and Metabolism · doi:10.1159/000440905 · Cited by 103

Does Inflammation Determine Whether Obesity Is Metabolically Healthy or Unhealthy? The Aging Perspective

Alam, I., Ng, T. P., & Larbi, A. (2012) · Mediators of Inflammation · doi:10.1155/2012/456456 · Cited by 102

Gastric Cancer after Roux-en-Y Gastric Bypass

Escalona, A., Guzmán, S., Ibañez, L. A., Meneses, L., Alvaro Huete, G., & Solar, A. A. (2005) · Obesity Surgery · doi:10.1381/0960892053576668 · Cited by 98

Reducing the risk of infection after total joint arthroplasty: preoperative optimization

Antonelli, B. J., & Chen, A. F. (2019) · Arthroplasty · doi:10.1186/s42836-019-0003-7 · Cited by 98

Calcitriol and calcium regulate cytokine production and adipocyte–macrophage cross-talk

Sun, X., & Zemel, M. B. (2007) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2007.05.013 · Cited by 95

Systemic inflammatory profiles and their relationships with demographic, behavioural and clinical features in acute low back pain

Klyne, D. M., Barbe, M. F., & Hodges, P. W. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.10.003 · Cited by 99

Serum leptin and adiponectin levels correlate with exercise-induced bronchoconstriction in children with asthma

Baek, H., Kim, Y.-D., Shin, J.-H., Kim, J.-H., Oh, J., & Lee, H.-B. (2011) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2011.03.013 · Cited by 93

Relationship between Single Nucleotide Polymorphisms in Leptin, IL6 and Adiponectin Genes and their Circulating Product in Morbidly Obese Subjects before and after Gastric Banding Surgery

Poitou, C., Lacorte, J., Coupaye, M., Bertrais, S., Bedel, J., Lafon, N., Bouillot, J., Galan, P., Borson‐Chazot, F., Basdevant, A., et al. (2005) · Obesity Surgery · doi:10.1381/0960892052993431 · Cited by 92

Correlation between estrogens and serum adipocytokines in premenopausal and postmenopausal women

Hong, S., Yoo, S. W., Cho, G. J., Kim, T., Hur, J. Y., Park, Y. K., Lee, K. W., & Kim, S. H. (2007) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e31802cddca · Cited by 91

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Baldelli, S., Aiello, G., Martino, E. M. D., Campaci, D., Muthanna, F. M. S., & Lombardo, M. (2024) · Nutrients · doi:10.3390/nu16152436 · Cited by 88

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Natal, C., Fortuño, M. A., Restituto, P., Bazán, A., Colina, I., Dı́ez, J., & Varo, N. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00506.2007 · Cited by 75

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