Recommendations for evaluation and treatment of common gastrointestinal problems in children with ASDs
Abstract
Children with autism spectrum disorders (ASDs) can benefit from adaptation of general pediatric guidelines for the diagnostic evaluation of abdominal pain, chronic constipation, and gastroesophageal reflux disease. These guidelines help health care providers determine when gastrointestinal symptoms are self-limited and when evaluation beyond a thorough medical history and physical examination should be considered. Children with ASDs who have gastrointestinal disorders may present with behavioral manifestations. Diagnostic and treatment recommendations for the general pediatric population are useful to consider until the development of evidence-based guidelines specifically for patients with ASDs.
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Individuals with ASD often suffer from gastrointestinal symptoms.
“Individuals with ASD often suffer from gastrointestinal (GI) symptoms [30,124].”
From Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions (2019) · cites this paper as [124]
Cites
Pediatric Gastroesophageal Reflux Clinical Practice Guidelines
Rosen, R., Vandenplas, Y., Singendonk, M. M. J., Cabana, M. D., DiLorenzo, C., Gottrand, F., Gupta, S. K., Langendam, M. W., Staiano, A., Thapar, N., et al. (2018) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000001889 · Cited by 1,559 · see citing works
Buie, T., Campbell, D. B., Fuchs, G. J., Furuta, G. T., Levy, J., VandeWater, J., Whitaker, A. H., Atkins, D., Bauman, M. L., Beaudet, A. L., et al. (2010) · Pediatrics · doi:10.1542/peds.2009-1878c · Cited by 872 · see citing works
Self-citationGuidelines for Evaluation and Treatment of Gastroesophageal Reflux in Infants and Children
Rudolph, C. D., Mazur, L. J., Liptak, G. S., Baker, R. D., Boyle, J. T., Colletti, R. B., Gerson, W. T., & Werlin, S. L. (2001) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-200100002-00001 · Cited by 618 · see citing works
The in-depth evaluation of suspected mitochondrial disease
Haas, R., Parikh, S., Falk, M. J., Saneto, R. P., Wolf, N. I., Darín, N., Wong, L.-J. C., Cohen, B. H., & Naviaux, R. K. (2008) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2007.11.018 · Cited by 363 · see citing works
Lorenzo, C. D., Colletti, R. B., Lehmann, H. P., Boyle, J. T., Gerson, W. T., Hyams, J. S., Squires, R. H., Walker, L. S., & Kanda, P. T. (2005) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/01.mpg.0000154661.39488.ac · Cited by 328 · see citing works
Evaluation and Treatment of Constipation in Infants and Children
Biggs, W. S., & Dery, W. H. (2006) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/01.mpg.0000233159.97667.c3 · Cited by 313 · see citing works
VALICENTI-McDERMOTT, M., McVICAR, K., RAPIN, I., WERSHIL, B. K., COHEN, H., & SHINNAR, S. (2006) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200604002-00011 · Cited by 302 · see citing works
Self-citationSteiner, T. S., Lima, A. Â. M., Nataro, J. P., & Guerrant, R. L. (1998) · The Journal of Infectious Diseases · doi:10.1086/513809 · Cited by 288 · see citing works
Mitochondrial Disease: A Practical Approach for Primary Care Physicians
Haas, R., Parikh, S., Falk, M. J., Saneto, R. P., Wolf, N. I., Darín, N., & Cohen, B. H. (2007) · PEDIATRICS · doi:10.1542/peds.2007-0391 · Cited by 272 · see citing works
Mitochondrial dysfunction in autism spectrum disorders: a population-based study
Oliveira, G., Diogo, L. M., Grazina, M. M., Garcia, P., Ataíde, A., Marques, C., Miguel, T., Borges, L., Vicente, A., & Oliveira, C. R. (2005) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162205000332 · Cited by 267 · see citing works
Mitochondrial Disease in Autism Spectrum Disorder Patients: A Cohort Analysis
Weissman, J. R., Kelley, R. I., Bauman, M. L., Cohen, B. H., Murray, K. F., Mitchell, R. L., Kern, R. L., & Natowicz, M. R. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003815 · Cited by 264 · see citing works
Autism and gastrointestinal symptoms
Horvath, K., & Perman, J. A. (2002) · Current Gastroenterology Reports · doi:10.1007/s11894-002-0071-6 · Cited by 260 · see citing works
Black, C., Kaye, J. A., & Jick, H. (2002) · BMJ · doi:10.1136/bmj.325.7361.419 · Cited by 240 · see citing works
Chronic abdominal pain in children
Berger, M. Y., Gieteling, M. J., & Benninga, M. A. (2007) · BMJ · doi:10.1136/bmj.39189.465718.be · Cited by 186 · see citing works
Making the best use of a department of clinical radiology--guidelines for doctors.
Needham, G. (1996) · PubMed · Cited by 178 · see citing works
Randomised trial of laxatives in treatment of childhood encopresis
Nolan, T. M., Coffey, C., Debelle, G. D., & Oberklaid, F. (1991) · The Lancet · doi:10.1016/0140-6736(91)91097-e · Cited by 151 · see citing works
Diagnostic Value of Abdominal Radiography in Constipated Children
Reuchlin-Vroklage, L. M., Bierma‐Zeinstra, S., Benninga, M. A., & Berger, M. Y. (2005) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.159.7.671 · Cited by 120 · see citing works
Chronic Abdominal Pain in Children
(2005) · PEDIATRICS · doi:10.1542/peds.2004-2497 · Cited by 106 · see citing works
Chronic constipation in children
Rubin, G. P., & Dale, A. (2006) · BMJ · doi:10.1136/bmj.39007.760174.47 · Cited by 57 · see citing works
Chitkara, D. K., Nurko, S., Shoffner, J. M., Buie, T. M., & Flores, A. (2003) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07385.x · Cited by 45 · see citing works
Self-citationMaking the Best Use of a Department of Clinical Radiology: Guidelines for Doctors
Bell, D. A. (2020) · Radiopaedia.org · doi:10.53347/rid-75466 · Cited by 30 · see citing works
Chronic Enteropathy: Clinical Aspects
Gibbons, T. E., & Fuchs, G. J. (2007) · KARGER eBooks · doi:10.1159/000098529 · Cited by 17 · see citing works
Self-citationEssential Pediatric Gastroenterology, Hepatology, and Nutrition
Guandalini, S. (2004) · Cited by 16 · see citing works
Nutrition Support for Infants and Children at Risk
Cooke, R. J., Vandenplas, Y., & Wahn, U. (2007) · doi:10.1159/isbn.978-3-318-01410-5 · Cited by 6 · see citing works
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Sorted by citations
Identification, Evaluation, and Management of Children With Autism Spectrum Disorder
Hyman, S. L., Levy, S. E., Myers, S. M., COUNCIL ON CHILDREN WITH DISABILITIES, S. O. D. A. B. P., Kuo, D. Z., Apkon, S., Davidson, L. F., Ellerbeck, K. A., Foster, J. E. A., Noritz, G. H., et al. (2020) · Pediatrics · doi:10.1542/peds.2019-3447 · Cited by 1,548 · see citing works
Current Understanding of Dysbiosis in Disease in Human and Animal Models
DeGruttola, A. K., Low, D., Mizoguchi, A., & Mizoguchi, E. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000750 · Cited by 1,122 · see citing works
Adams, J. B., Johansen, L. J., Powell, L. D., Quig, D., & Rubin, R. A. (2011) · BMC Gastroenterology · doi:10.1186/1471-230x-11-22 · Cited by 1,076 · see citing works
Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis
Rossignol, D. A., & Frye, R. E. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.136 · Cited by 913 · see citing works
De Angelis, M., Piccolo, M., Vannini, L., Siragusa, S., De Giacomo, A., Serrazzanetti, D. I., Cristofori, F., Guerzoni, M. E., Gobbetti, M., & Francavilla, R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076993 · Cited by 887 · see citing works
Gastrointestinal Problems in Children with Autism, Developmental Delays or Typical Development
Chaidez, V., Hansen, R. L., & Hertz-Picciotto, I. (2014) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-013-1973-x · Cited by 528 · see citing works
The Gut Microbiota and Autism Spectrum Disorders
Li, Q., Han, Y., Dy, A. B. C., & Hagerman, R. J. (2017) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2017.00120 · Cited by 462 · see citing works
Medical Comorbidities in Autism: Challenges to Diagnosis and Treatment
Bauman, M. L. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.06.001 · Cited by 372 · see citing works
Microbiota regulate social behaviour via stress response neurons in the brain
Wu, W., Adame, M. D., Liou, C.-W., Barlow, J. T., Lai, T.-T., Sharon, G., Schretter, C. E., Needham, B. D., Wang, M., Tang, W., et al. (2021) · Nature · doi:10.1038/s41586-021-03669-y · Cited by 344 · see citing works
The Impact of Microbiota on Brain and Behavior: Mechanisms & Therapeutic Potential
Borre, Y. E., Moloney, R. D., Clarke, G., Dinan, T. G., & Cryan, J. F. (2014) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4939-0897-4_17 · Cited by 329 · see citing works
Cross talk: the microbiota and neurodevelopmental disorders
Kelly, J. R., Minuto, C., Cryan, J. F., Clarke, G., & Dinan, T. G. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00490 · Cited by 271 · see citing works
Comorbidity in autism spectrum disorder: a literature review
Mannion, A., & Leader, G. (2013) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2013.09.006 · Cited by 271 · see citing works
Gastrointestinal Conditions in Children With Autism Spectrum Disorder: Developing a Research Agenda
Coury, D. L., Ashwood, P., Fasano, A., Fuchs, G., Geraghty, M., Kaul, A., Mawe, G., Patterson, P., & Jones, N. E. (2012) · Pediatrics · doi:10.1542/peds.2012-0900n · Cited by 264 · see citing works
Self-citationAdams, J., Audhya, T., Geis, E., Gehn, E., Fimbres, V., Pollard, E., Mitchell, J., Ingram, J., Hellmers, R., Laake, D., et al. (2018) · Nutrients · doi:10.3390/nu10030369 · Cited by 267 · see citing works
Autism: the micro-movement perspective
Torres, E. B., Brincker, M., Isenhower, R. W., Yanovich, P., Stigler, K. A., Nürnberger, J. I., Metaxas, D., & José, J. V. (2013) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2013.00032 · Cited by 256 · see citing works
Lai, M.-C., Anagnostou, E., Wiznitzer, M., Allison, C., & Baron-Cohen, S. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(20)30034-x · Cited by 250 · see citing works
The microbiome in respiratory medicine: current challenges and future perspectives
Faner, R., Sibila, O., Agustí, A., Bernasconi, E., Chalmers, J. D., Huffnagle, G. B., Manichanh, C., Molyneaux, P. L., Paredes, R., Pérez Brocal, V., et al. (2017) · European Respiratory Journal · doi:10.1183/13993003.02086-2016 · Cited by 247 · see citing works
Frye, R. E., & Rossignol, D. A. (2011) · Pediatric Research · doi:10.1203/pdr.0b013e318212f16b · Cited by 217 · see citing works
Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions
Ristori, M. V., Quagliariello, A., Reddel, S., Ianiro, G., Vicari, S., Gasbarrini, A., & Putignani, L. (2019) · Nutrients · doi:10.3390/nu11112812 · Cited by 214 · see citing works
Gastrointestinal issues in autism spectrum disorder
Hsiao, E. Y. (2014) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000029 · Cited by 209 · see citing works
Valenti, D., Lidia de, B. A. R. I., Filippis, B. D., Henrion‐Caude, A., & Vacca, R. A. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.01.012 · Cited by 189 · see citing works
Wasilewska, J., & Klukowski, M. (2015) · Pediatric Health Medicine and Therapeutics · doi:10.2147/phmt.s85717 · Cited by 184 · see citing works
Tye, C., Runicles, A. K., Whitehouse, A. J. O., & Alvares, G. A. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00751 · Cited by 177 · see citing works
Modeling Autistic Features in Animals
Patterson, P. H. (2011) · Pediatric Research · doi:10.1203/pdr.0b013e318212b80f · Cited by 169 · see citing works
Antipurinergic Therapy Corrects the Autism-Like Features in the Poly(IC) Mouse Model
Naviaux, R. K., Zolkipli‐Cunningham, Z., Wang, L., Nakayama, T., Naviaux, J. C., Le, T., Schuchbauer, M. A., Rogač, M., Tang, Q., Dugan, L. L., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057380 · Cited by 171 · see citing works
Krajmalnik‐Brown, R., Lozupone, C., Kang, D., & Adams, J. B. (2015) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v26.26914 · Cited by 167 · see citing works
Clinical differences in children with autism spectrum disorder with and without food selectivity
Postorino, V., Sanges, V., Giovagnoli, G., Fatta, L. M., De Peppo, L., Armando, M., Vicari, S., & Mazzone, L. (2015) · Appetite · doi:10.1016/j.appet.2015.05.016 · Cited by 151 · see citing works
Plaza‐Díaz, J., Gómez-Fernández, A., Chueca, N., de la Torre‐Aguilar, M. J., Gil, Á., Pérez-Navero, J. L., Flores‐Rojas, K., Martín-Borreguero, P., Solis‐Urra, P., Ruiz‐Ojeda, F. J., et al. (2019) · Nutrients · doi:10.3390/nu11020337 · Cited by 124 · see citing works
Mazefsky, C. A., Schreiber, D. R., Olino, T. M., & Minshew, N. J. (2013) · Autism · doi:10.1177/1362361313485164 · Cited by 122 · see citing works
Autism and mitochondrial disease
Haas, R. (2010) · Developmental Disabilities Research Reviews · doi:10.1002/ddrr.112 · Cited by 113 · see citing works
Effect of suboptimal breast-feeding on occurrence of autism: A case–control study
Al-Farsi, Y. M., Al‐Sharbati, M. M., Waly, M. I., Al-Farsi, O. A., Al‐Shafaee, M., Al‐Khaduri, M., Trivedi, M. S., & Deth, R. C. (2012) · Nutrition · doi:10.1016/j.nut.2012.01.007 · Cited by 109 · see citing works
Wang, X., Yang, J., Zhang, H., Yu, J., & Yao, Z. (2019) · Autism Research · doi:10.1002/aur.2079 · Cited by 107 · see citing works
Racial and Ethnic Differences in Subspecialty Service Use by Children With Autism
Broder‐Fingert, S., Shui, A. M., Pulcini, C. D., Kurowski, D., & Perrin, J. M. (2013) · PEDIATRICS · doi:10.1542/peds.2012-3886 · Cited by 107 · see citing works
Eating and feeding problems and gastrointestinal dysfunction in Autism Spectrum Disorders
Vissoker, R. E., Latzer, Y., & Gal, E. (2015) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2014.12.010 · Cited by 105 · see citing works
Gastrointestinal dysfunction in children with autism spectrum disorders
Kang, V., Wagner, G. C., & Ming, X. (2014) · Autism Research · doi:10.1002/aur.1386 · Cited by 101 · see citing works
Gastrointestinal involvement of autism spectrum disorder: focus on gut microbiota
Settanni, C. R., Bibbò, S., Ianiro, G., Rinninella, E., Cintoni, M., Mele, M. C., Cammarota, G., & Gasbarrini, A. (2021) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2021.1869938 · Cited by 98 · see citing works
Frye, R. E., & Rossignol, D. A. (2016) · Clinical Medicine Insights Pediatrics · doi:10.4137/cmped.s38337 · Cited by 96 · see citing works
Dargenio, V. N., Dargenio, C., Castellaneta, S., De Giacomo, A., Laguardia, M., Schettini, F., Francavilla, R., & Cristofori, F. (2023) · Nutrients · doi:10.3390/nu15071620 · Cited by 98 · see citing works
Sichel, J. P. (2013) · Journal of Probiotics & Health · doi:10.4172/2329-8901.1000102 · Cited by 89 · see citing works
Management of constipation in children and adolescents with autism spectrum disorders
Furuta, G. T., Williams, K., Kooros, K., Kaul, A., Panzer, R., Coury, D. L., & Fuchs, G. (2012) · PEDIATRICS · doi:10.1542/peds.2012-0900h · Cited by 88 · see citing works
Self-citationIn pursuit of neurophenotypes: The consequences of having autism and a big brain
Amaral, D. G., Li, D., Libero, L. E., Solomon, M., de Water, J. V., Mastergeorge, A. M., Naigles, L., Rogers, S. J., & Nordahl, C. W. (2017) · Autism Research · doi:10.1002/aur.1755 · Cited by 88 · see citing works
Hosie, S., Ellis, M., Swaminathan, M., Ramalhosa, F., Seger, G. O., Balasuriya, G. K., Gillberg, C., Råstam, M., Churilov, L. P., McKeown, S. J., et al. (2019) · Autism Research · doi:10.1002/aur.2127 · Cited by 84 · see citing works
Rose, S., Bennuri, S. C., Murray, K. F., Buie, T., Winter, H., & Frye, R. E. (2017) · PLOS ONE · doi:10.1371/journal.pone.0186377 · Cited by 82 · see citing works
Self-citationBehavioral Phenotype of ASD Preschoolers with Gastrointestinal Symptoms or Food Selectivity
Prosperi, M., Santocchi, E., Balboni, G., Narzisi, A., Bozza, M., Fulceri, F., Apicella, F., Igliozzi, R., Cosenza, A., Tancredi, R., et al. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3271-5 · Cited by 82 · see citing works
Good or bad: gut bacteria in human health and diseases
Wang, H., Wei, C.-X., Lu, M., & Zhu, L. (2018) · Biotechnology & Biotechnological Equipment · doi:10.1080/13102818.2018.1481350 · Cited by 84 · see citing works
Autism spectrum disorders and allergy: observation from a pediatric allergy/immunology clinic
Jyonouchi, H. (2010) · Expert Review of Clinical Immunology · doi:10.1586/eci.10.18 · Cited by 80 · see citing works
Bruce-Keller, A. J., Fernandez-Kim, S.-O., Townsend, R. L., Kruger, C., Carmouche, R., Newman, S., Salbaum, J. M., & Berthoud, H.-R. (2017) · PLoS ONE · doi:10.1371/journal.pone.0175577 · Cited by 76 · see citing works
The Brain-Gut-Microbiome Axis: What Role Does it Play in Autism Spectrum Disorder?
Luna, R. A., Savidge, T., & Williams, K. C. (2016) · Current Developmental Disorders Reports · doi:10.1007/s40474-016-0077-7 · Cited by 73 · see citing works
Mezzelani, A., Landini, M., Facchiano, F., Raggi, M. E., Villa, L. M., Molteni, M., Santis, B. D., Brera, C., Caroli, A. M., Milanesi, L., et al. (2014) · Nutritional Neuroscience · doi:10.1179/1476830513y.0000000108 · Cited by 71 · see citing works
AL-Ayadhi, L. Y., Zayed, N., Bhat, R. S., Moubayed, N., Al-Muammar, M. N., & El-Ansary, A. (2021) · Gut Pathogens · doi:10.1186/s13099-021-00448-y · Cited by 70 · see citing works
Turck, D. (2013) · World review of nutrition and dietetics · doi:10.1159/000351485 · Cited by 70 · see citing works
The Gut Microbiota and Oxidative Stress in Autism Spectrum Disorders (ASD)
Hu, T., Dong, Y., He, C., Zhao, M., & He, Q. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/8396708 · Cited by 71 · see citing works
Is Cow's Milk Harmful to a Child's Health?
Agostoni, C. V., & Turck, D. (2011) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e318235b23e · Cited by 65 · see citing works
Age of Onset of Functional Constipation
Malowitz, S. M., Green, M., Karpinski, A. C., Rosenberg, A. J., & Hyman, P. E. (2015) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000001011 · Cited by 63 · see citing works
Navaneetharaja, N., Griffiths, V., Wileman, T., & Carding, S. R. (2016) · Journal of Clinical Medicine · doi:10.3390/jcm5060055 · Cited by 60 · see citing works
Zheng, Y., Bek, M. K., Prince, N., Marzal, L. N. P., Garssen, J., Perez‐Pardo, P., & Kraneveld, A. D. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.738220 · Cited by 58 · see citing works
Mostafa, G. A., & AL-Ayadhi, L. Y. (2015) · Behavioral and Brain Functions · doi:10.1186/s12993-014-0048-2 · Cited by 54 · see citing works
Nutrition and Bone Density in Boys with Autism Spectrum Disorder
Neumeyer, A. M., Sokoloff, N. C., McDonnell, E., Macklin, E. A., McDougle, C. J., Holmes, T. M., Hubbard, J. L., & Misra, M. (2018) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2017.11.006 · Cited by 53 · see citing works
Studying Autism in Rodent Models: Reconciling Endophenotypes with Comorbidities
Argyropoulos, A., Gilby, K. L., & Hill‐Yardin, E. L. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00417 · Cited by 51 · see citing works
The microbiome and childhood diseases: Focus on brain‐gut axis
O’Mahony, S. M., Stilling, R. M., Dinan, T. G., & Cryan, J. F. (2015) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.21118 · Cited by 50 · see citing works
Gastrointestinal problems in 15q duplication syndrome
Shaaya, E. A., Pollack, S. F., Boronat, S., Davis-Cooper, S., Zella, G. C., & Thibert, R. L. (2015) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2014.12.012 · Cited by 48 · see citing works
Caregiver burden among caregivers of children with autism spectrum disorder
van Niekerk, K., Stancheva, V. P., & Smith, C. (2023) · South African Journal of Psychiatry · doi:10.4102/sajpsychiatry.v29i0.2079 · Cited by 48 · see citing works
Sexuality and Sexual Health in Children and Adolescents With Autism
Chan, J., & John, R. M. (2012) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2012.01.020 · Cited by 47 · see citing works
Evidence-Based Treatments for Autism Spectrum Disorder
Politte, L. C., Howe, Y. J., Nowinski, L. A., Palumbo, M., & McDougle, C. J. (2015) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-015-0031-z · Cited by 48 · see citing works
Hodgson, N., Waly, M. I., Al-Farsi, Y. M., Al‐Sharbati, M. M., Al-Farsi, O. A., Ali, A., Ouhtit, A., Zang, T., Zhou, Z. S., & Deth, R. C. (2014) · Experimental Biology and Medicine · doi:10.1177/1535370214527900 · Cited by 47 · see citing works
Gut Permeability in Autism Spectrum Disorders
Dalton, N. R., Chandler, S., Turner, C., Charman, T., Pickles, A. R., Loucas, T., Simonoff, E. A., Sullivan, P. B., & Baird, G. (2013) · Autism Research · doi:10.1002/aur.1350 · Cited by 48 · see citing works
Gastrointestinal Symptoms in Autism Spectrum Disorder: A Literature Review
Mannion, A., & Leader, G. (2014) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-013-0007-0 · Cited by 45 · see citing works
Allan, N. P., Yamamoto, B. Y., Kunihiro, B. P., Nunokawa, C. K. L., Rubas, N. C., Wells, R. K., Umeda, L., Phankitnirundorn, K., Torres, A., Peres, R., et al. (2024) · Nutrients · doi:10.3390/nu16101401 · Cited by 44 · see citing works
Evolution in the Understanding of Autism Spectrum Disorder: Historical Perspective
Mintz, M. (2016) · The Indian Journal of Pediatrics · doi:10.1007/s12098-016-2080-8 · Cited by 44 · see citing works
Angell, A. M., Deavenport‐Saman, A., Yin, L., Zou, B., Bai, C., Varma, D. S., & Solomon, O. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04841-5 · Cited by 44 · see citing works
Edelson, S. M. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12071127 · Cited by 42 · see citing works
Dalwai, S. H., Ahmed, S., Udani, V. P., Mundkur, N., Kamath, S. S., & Nair, M. K. C. (2017) · Indian Pediatrics · doi:10.1007/s13312-017-1112-4 · Cited by 42 · see citing works
Care of the patient with an autism spectrum disorder by the general physician
Venkat, A., Jauch, E. C., Russell, W. S., Crist, C. R., & Farrell, R. (2012) · Postgraduate Medical Journal · doi:10.1136/postgradmedj-2011-130727 · Cited by 43 · see citing works
Carpita, B., Marazziti, D., Palego, L., Giannaccini, G., Betti, L., & Dell’Osso, L. (2019) · Current Medicinal Chemistry · doi:10.2174/0929867326666190328151539 · Cited by 40 · see citing works
Goyal, D. K., & Miyan, J. A. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00029 · Cited by 38 · see citing works
Olteanu, G., Pană, M.-A., Busnatu, Ș., Lupuliasa, D., Neacșu, S. M., Mititelu, M., Musuc, A. M., Ioniță-Mîndrican, C.-B., & Boroghină, S. C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25105561 · Cited by 34 · see citing works
Moving From Research to Practice in the Primary Care of Children With Autism Spectrum Disorders
Carbone, P. S. (2013) · Academic Pediatrics · doi:10.1016/j.acap.2013.04.003 · Cited by 33 · see citing works
Gorrindo, P., Lane, C. J., Lee, E. B., McLaughlin, B., & Levitt, P. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068444 · Cited by 32 · see citing works
Investigating Potential Biomarkers in Autism Spectrum Disorder
Bridgemohan, C. F., Cochran, D., Howe, Y. J., Pawlowski, K. G., Zimmerman, A. W., Anderson, G. M., Choueiri, R., Sices, L., Miller, K. J., Ultmann, M. H., et al. (2019) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2019.00031 · Cited by 32 · see citing works
Thulasi, V., Steer, R. A., Monteiro, I. M., & Ming, X. (2018) · Autism · doi:10.1177/1362361318757564 · Cited by 31 · see citing works
Barnhill, K. M., Devlin, M., Moreno, H. T., Potts, A., Richardson, W., Schutte, C., & Hewitson, L. C. (2018) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-018-3704-9 · Cited by 31 · see citing works
Nutritional Interventions and Therapies in Autism
Geraghty, M. E., Bates-Wall, J., Ratliff-Schaub, K. L., & Lane, A. E. (2010) · ICAN Infant Child & Adolescent Nutrition · doi:10.1177/1941406410366848 · Cited by 30 · see citing works
Fu, S.-C., Lee, C., & Wang, H. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18020667 · Cited by 29 · see citing works
Gal, E., Gal-Mishael, R., Vissoker, R. E., Hedley, D., Bury, S. M., & Stolar, O. E. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-021-04978-x · Cited by 30 · see citing works
Torres, E. B., Isenhower, R. W., Yanovich, P., Rehrig, G., Stigler, K. A., Nürnberger, J. I., & José, J. V. (2013) · Journal of Neurophysiology · doi:10.1152/jn.00059.2013 · Cited by 28 · see citing works
Gut Microbiota and Fecal Metabolome Perturbation in Children with Autism Spectrum Disorder
Mohamadkhani, A. (2018) · Middle East Journal of Digestive Diseases · doi:10.15171/mejdd.2018.112 · Cited by 27 · see citing works
Leader, G., & Mannion, A. (2015) · Autism and child psychopathology series · doi:10.1007/978-3-319-19183-6_11 · Cited by 25 · see citing works
Challenges in the Diagnosis and Management of Pain in Individuals with Autism Spectrum Disorder
Liu, J., Chen, L. L., Shen, S., Mao, J., Lopes, M. S. O. C., Liu, S., & Kong, X. (2020) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-020-00199-7 · Cited by 25 · see citing works
Bradley, E. A., Caldwell, P., & Underwood, L. (2013) · Autism and child psychopathology series · doi:10.1007/978-1-4614-8250-5_16 · Cited by 24 · see citing works
Mack, D. L., Guan, X., Wagoner, A. L., Walker, S. J., & Childers, M. K. (2014) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0000000000000141 · Cited by 23 · see citing works
Waly, M. I., Hornig, M., Trivedi, M. S., Hodgson, N., Kini, R., Ohta, A., & Deth, R. C. (2012) · Autism Research and Treatment · doi:10.1155/2012/190930 · Cited by 23 · see citing works
The Autism Treatment Network: Bringing Best Practices to All Children With Autism
Coury, D. L., Murray, D. S., Fedele, A., Hess, T., Kelly, A. M., & Kuhlthau, K. A. (2020) · PEDIATRICS · doi:10.1542/2019-1895d · Cited by 22 · see citing works
Retuerto, M., Al-Shakhshir, H., Herrada, J., McCormick, T. S., & Ghannoum, M. A. (2024) · Nutrients · doi:10.3390/nu16173004 · Cited by 24 · see citing works
Brown, A. C., & Mehl‐Madrona, L. (2011) · Expert Review of Gastroenterology & Hepatology · doi:10.1586/egh.11.46 · Cited by 21 · see citing works
Gastrointestinal disease in children with autism spectrum disorders: Etiology or consequence?
Krigsman, A., & Walker, S. J. (2021) · World Journal of Psychiatry · doi:10.5498/wjp.v11.i9.605 · Cited by 22 · see citing works
House, S. A., Goodman, D. C., Weinstein, S. J., Chang, C., Wasserman, J. R., & Morden, N. E. (2015) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2015.10.027 · Cited by 21 · see citing works
Autism and Our Intestinal Microbiota
Reddy, B. L., & Saier, M. H. (2015) · Microbial Physiology · doi:10.1159/000375303 · Cited by 21 · see citing works
Etiology of Autism the Complexity of Risk Factors in Autism Spectrum Disorder
Fett‐Conte, A. C., Bossolani-Martins, A. L., & Rosan, D. B. A. (2015) · InTech eBooks · doi:10.5772/59109 · Cited by 21 · see citing works
Bone Mineral Density in Boys Diagnosed with Autism Spectrum Disorder: A Case-Control Study
Barnhill, K. M., Ramirez, L., Gutierrez, A., Richardson, W., Marti, C. N., Potts, A., Shearer, R., Schutte, C., & Hewitson, L. C. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3277-z · Cited by 18 · see citing works
New Assessments and Treatments in ASD
Choueiri, R., & Zimmerman, A. W. (2017) · Current Treatment Options in Neurology · doi:10.1007/s11940-017-0443-8 · Cited by 17 · see citing works
- Authors
- Buie, T., Fuchs, G. J., Furuta, G. T., Kooros, K., Levy, J., Lewis, J. D., Wershil, B. K., & Winter, H.
- Affiliations
- Harvard University (US)
- Arkansas Children's Hospital (US)
- University of Southern California (US)
- University of Rochester Medicine (US)
- NYU Langone Health (US)
- Children's Center for Digestive Health Care, LLC, Atlanta, Georgia; and
- Northwestern University (US)
- Corresponding author
- Buie, Timothy
- Winter, Harland
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2010-01-01
- Volume
- 125
- Issue
- Supplement_1
- Pages
- S19-S29
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2020860195
- Cited by
- 228
- References
- 24
- Citations by year
- 2026: 7 · 2025: 2 · 2024: 15 · 2023: 10 · 2022: 7 · 2021: 17 · 2020: 18 · 2019: 17 · 2018: 18 · 2017: 14 · 2016: 14 · 2015: 19 · 2014: 17 · 2013: 21 · 2012: 14
- FWCI
- 11.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- PEDIATRICS (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Keywords
- autism spectrum disorder, gastrointestinal symptoms, abdominal pain, chronic constipation, gastroesophageal reflux disease, diagnostic assessment, treatment guidelines, behavioral manifestations
- MeSH terms
- Algorithms, Child, Child Development Disorders, Pervasive, Chronic Disease, Constipation, Diagnosis, Differential, Diarrhea, Gastroesophageal Reflux, Humans, Physical Examination, Abdominal Pain, Mitochondrial Diseases
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