Spirulina prevents memory dysfunction, reduces oxidative stress damage and augments antioxidant activity in senescence-accelerated mice
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Spirulina has proven to be effective in treating certain cancers, hyperlipidemia, immunodeficiency, and inflammatory processes. In this study, we aimed to investigate the effects of Spirulina on memory dysfunction, oxidative stress damage and antioxidant enzyme activity. Three-month-old male senescence-accelerated prone-8 (SAMP8) mice were randomly assigned to either a control group or to one of two experimental groups (one receiving daily dietary supplementation with 50 mg/kg BW and one with 200 mg/kg BW of Spirulina platensis water extract). Senescence-accelerated-resistant (SAMR1) mice were used as the external control. Results showed that the Spirulina-treated groups had better passive and avoidance scores than the control group. The amyloid β-protein (Aβ) deposition was significantly reduced at the hippocampus and whole brain in both Spirulina groups. The levels of lipid peroxidation were significantly reduced at the hippocampus, striatum, and cortex in both Spirulina groups, while catalase activity was significantly higher only in the 200 mg/kg BW Spirulina group than in the control group. Glutathione peroxidase activity was significantly higher only in the cortex of the 200 mg/kg group than in that of the SAMP8 control group. However, superoxide dismutase activity in all parts of the brain did not significantly differ among all groups. In conclusion, Spirulina platensis may prevent the loss of memory possibly by lessening Aβ protein accumulation, reducing oxidative damage and mainly augmenting the catalase activity.
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Some authors have reported that Arthrospira platensis supports the resistance to the oxidative aspect of microglial cell activity and fights against memory loss.
“Some authors have reported that Arthrospira platensis supports the resistance to the oxidative aspect of microglial cell activity and fights against memory loss [92,93].”
From Application of Arthrospira platensis for Medicinal Purposes and the Food Industry: A Review of the Literature (2023) · cites this paper as [93]
The Discussion (page not provided) reports that Spirulina platensis extract slowed memory loss and reduced oxidative damage in senescence-accelerated mice. The paper does not connect those effects to the oxidative aspect of microglial cell activity; its reference to microglial activation concerns a different study. (LLM, conf=0.86)
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Cites
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
Ohkawa, H., Ohishi, N., & Yagi, K. (1979) · Analytical Biochemistry · doi:10.1016/0003-2697(79)90738-3 · Cited by 29,460 · see citing works
(1975) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/58.5.1085 · Cited by 20,078 · see citing works
Marklund, S. L., & MARKLUND, G. (1974) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1974.tb03714.x · Cited by 10,382 · see citing works
Aebi, H. E. (1974) · Elsevier eBooks · doi:10.1016/b978-0-12-091302-2.50032-3 · Cited by 2,075 · see citing works
Dalgleish, T. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1432 · Cited by 1,849 · see citing works
Ibuprofen Suppresses Plaque Pathology and Inflammation in a Mouse Model for Alzheimer's Disease
Lim, G. P., Yang, F., Chu, T., Chen, P., Beech, W. K., Teter, B., Tran, T., Ubeda, O. J., Ashe, K. H., Frautschy, S. A., et al. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-15-05709.2000 · Cited by 876 · see citing works
A new murine model of accelerated senescence
Takeda, T., HOSOKAWA, M., TAKESHITA, S., Irino, M., Higuchi, K., Matsushita, T., Tomita, Y., Yasuhira, K., Hamamoto, H., & Shimizu, K. (1981) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(81)90084-1 · Cited by 871 · see citing works
C-Phycocyanin: A potent peroxyl radical scavenger in Vivo and in Vitro
Bhat, V. B., & Madyastha, K. M. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3270 · Cited by 477 · see citing works
Butterfield, D. A., & Poon, H. F. (2005) · Experimental Gerontology · doi:10.1016/j.exger.2005.05.007 · Cited by 328 · see citing works
Takeda, T. (2009) · Neurochemical Research · doi:10.1007/s11064-009-9922-y · Cited by 233 · see citing works
Massaad, C. A., Washington, T. M., Pautler, R. G., & Klann, E. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902714106 · Cited by 223 · see citing works
Dietary supplementation with blueberries, spinach, or spirulina reduces ischemic brain damage
Wang, Y., Chang, C.-F., Chou, J., Chen, H.-L., Deng, X., Harvey, B. K., Cadet, J. L., & Bickford, P. C. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2004.12.014 · Cited by 223 · see citing works
A colour atlas of the anatomy of small laboratory animals
Popesko, P., Rajtová, V., & Horák, J. (1992) · Medical Entomology and Zoology · Cited by 204 · see citing works
Tha, K. K., Okuma, Y., Miyazaki, H., Murayama, T., Uehara, T., Hatakeyama, R., Hayashi, Y., & Nomura, Y. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02883-3 · Cited by 163 · see citing works
Viña, J. (2004) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2004.02.013 · Cited by 142 · see citing works
Flood, J. F., & Morley, J. E. (1993) · Neurobiology of Aging · doi:10.1016/0197-4580(93)90091-o · Cited by 125 · see citing works
Mesolimbic interaction of emotional valence and reward improves memory formation.
Wittmann, B., Schiltz, K., Boehler, C., & Düzel, E. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2007.11.020 · Cited by 124 · see citing works
Mitochondrial Dysfunction in the Senescence Accelerated Mouse (SAM)
Nakahara, H., Kanno, T., Inai, Y., Utsumi, K., Hiramatsu, M., Mori, A., & Packer, L. (1998) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(97)00164-0 · Cited by 120 · see citing works
Strömberg, I., Gemma, C., Vila, J., & Bickford, P. C. (2005) · Experimental Neurology · doi:10.1016/j.expneurol.2005.08.013 · Cited by 110 · see citing works
Khan, M., Varadharaj, S., Ganesan, L. P., Shobha, J. C., Naidu, M. U. R., Parinandi, N. L., Tridandapani, S., Kutala, V. K., & Kuppusamy, P. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01072.2005 · Cited by 105 · see citing works
Liu, J., & Mori, A. (1993) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(93)90032-m · Cited by 104 · see citing works
[Update on the pharmacology of Spirulina (Arthrospira), an unconventional food].
Chamorro, G., Salazar, M., Araújo, K. G. D. L., Santos, C. P. D., Ceballos, G. M., & Castillo, L. F. (2002) · PubMed · Cited by 86 · see citing works
Cultivation of Spirulina platensis Using Pig Wastewater in a Semi-Continuous Process
Chaiklahan, R. (2010) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.0907.07026 · Cited by 80 · see citing works
Drinking Hydrogen Water Ameliorated Cognitive Impairment in Senescence-Accelerated Mice
Gu, Y., Huang, C., Inoue, T., Yamashita, T., Ishida, T., Kang, K.-M., & Nakao, A. (2010) · Journal of Clinical Biochemistry and Nutrition · doi:10.3164/jcbn.10-19 · Cited by 69 · see citing works
Chamorro, G., Pérez-Albiter, M., Serrano-García, N., Mares-Sámano, J. J., & Rojas, P. (2006) · Nutritional Neuroscience · doi:10.1080/10284150600929748 · Cited by 50 · see citing works
Studies on the qualitative characterization of erythrocyte glutathione peroxidase
De, P. (1967) · Journal of Laboratory and Clinical Medicine · Cited by 45 · see citing works
Thaakur, S. R., & Jyothi, B. (2007) · Journal of Neural Transmission · doi:10.1007/s00702-007-0744-2 · Cited by 44 · see citing works
Ferreira, T. L., Shammah‐Lagnado, S. J., Bueno, O. F. A., Moreira, K. D. M., Fornari, R. V., & Oliveira, M. G. M. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.02.013 · Cited by 43 · see citing works
Roy, K. R., Arunasree, K. M., Dhoot, A., Rachamallu, A., Reddy, G. V., Vali, S., & Reddanna, P. (2007) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2007.01.006 · Cited by 29 · see citing works
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The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: An overview
Wu, Q., Liu, L., Miron, A., Klímová, B., Wan, D., & Kuča, K. (2016) · Archives of Toxicology · doi:10.1007/s00204-016-1744-5 · Cited by 655 · see citing works
NUTRITIONAL AND TOXICOLOGICAL ASPECTS OF SPIRULINA (ARTHROSPIRA).
Gutiérrez-Salmeán, G., Castillo, L., & Chamorro, G. (2015) · PubMed · doi:10.3305/nh.2015.32.1.9001 · Cited by 212 · see citing works
‘Nutritional and healthical aspects of spirulina (Arthrospira) for poultry, animals and human.
Farag, M. R., Alagawany, M., Abd El-Hac, M. E., & Dhama, K. (2015) · International Journal of Pharmacology · doi:10.3923/ijp.2016.36.51 · Cited by 117 · see citing works
Ku, C. S., Yang, Y. J., Park, Y., & Lee, J. (2013) · Journal of Medicinal Food · doi:10.1089/jmf.2012.2468 · Cited by 113 · see citing works
Anti-Oxidation Properties and Therapeutic Potentials of Spirulina
Han, P., Li, J., Zhong, H., Xie, J., Zhang, P., Lu, Q., Li, J., Xu, P., Chen, P., Leng, L., et al. (2021) · Algal Research · doi:10.1016/j.algal.2021.102240 · Cited by 109 · see citing works
Chen, J.-C., Liu, K. S., Yang, T.-J., Hwang, J.-H., Chan, Y., & Lee, I. (2012) · Nutritional Neuroscience · doi:10.1179/1476830512y.0000000020 · Cited by 109 · see citing works
Self-citationGentscheva, G., Nikolova, K., Panayotova, V., Peycheva, K., Makedonski, L., Slavov, P., Radusheva, P., Petrova, P., & Yotkovska, I. (2023) · Life · doi:10.3390/life13030845 · Cited by 106 · see citing works
Quercetin improves cognitive disorder in aging mice by inhibiting NLRP3 inflammasome activation
Li, H., Chen, F.-J., Yang, W., Qiao, H., & Zhang, S. (2020) · Food & Function · doi:10.1039/d0fo01900c · Cited by 109 · see citing works
Czerwonka, A., Kaławaj, K., Sławińska-Brych, A., Lemieszek, M. K., Bartnik, M., Wojtanowski, K. K., Zdzisińska, B., & Rzeski, W. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.06.116 · Cited by 101 · see citing works
Wide range applications of spirulina: from earth to space missions
Fais, G., Manca, A., Bolognesi, F., Borselli, M., Concas, A., Busutti, M., Broggi, G., Sanna, P., Castillo-Aleman, Y. M., Rivero-Jiménez, R. A., et al. (2022) · Marine Drugs · doi:10.3390/md20050299 · Cited by 98 · see citing works
Spirulina Microalgae and Brain Health: A Scoping Review of Experimental and Clinical Evidence
Sorrenti, V., Castagna, D. A., Fortinguerra, S., Buriani, A., Scapagnini, G., & Willcox, D. C. (2021) · Marine Drugs · doi:10.3390/md19060293 · Cited by 94 · see citing works
Wan, X., Li, T.-T., Zhong, R.-T., Chen, H., Xia, X., Gao, L., Gao, X., Liu, B., Zhang, H., & Zhao, C. (2019) · Food and Chemical Toxicology · doi:10.1016/j.fct.2019.04.017 · Cited by 89 · see citing works
Understanding Epigenetics in the Neurodegeneration of Alzheimer’s Disease: SAMP8 Mouse Model
Griñán‐Ferré, C., Corpas, R., Puigoriol‐Illamola, D., Palomera‐Ávalos, V., Sanfeliu, C., & Pallàs, M. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170664 · Cited by 83 · see citing works
Gogna, S., Kaur, J., Sharma, K., Prasad, R., Singh, J., Bhadariya, V., Kumar, P., & Jarial, S. (2023) · Journal of the American Nutrition Association · doi:10.1080/27697061.2022.2103852 · Cited by 83 · see citing works
Hwang, J.-H., Chen, J.-C., & Chan, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0058215 · Cited by 80 · see citing works
Self-citationMitra, S., Siddiqui, W. A., & Khandelwal, S. (2015) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2015.06.016 · Cited by 67 · see citing works
Obstructive sleep apnea and risk of Parkinson's disease: a population‐based cohort study
Chen, J., Tsai, T., Li, C., & Hwang, J.-H. (2015) · Journal of Sleep Research · doi:10.1111/jsr.12289 · Cited by 58 · see citing works
Self-citationCyanotherapeutics: An emerging field for future drug discovery
Tiwari, A. K., & Tiwari, B. S. (2020) · Applied Phycology · doi:10.1080/26388081.2020.1744480 · Cited by 49 · see citing works
Beneficial Effects of Citrus-Derived Polymethoxylated Flavones for Central Nervous System Disorders
Matsuzaki, K., & Ohizumi, Y. (2021) · Nutrients · doi:10.3390/nu13010145 · Cited by 49 · see citing works
Early onset of behavioral alterations in senescence-accelerated mouse prone 8 (SAMP8)
Yanai, S., & Endo, S. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.04.026 · Cited by 47 · see citing works
Sinha, S., Patro, N., & Patro, I. K. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00966 · Cited by 49 · see citing works
Kumar, A., Christian, P. K., Panchal, K., Guruprasad, B. R., & Tiwari, A. K. (2017) · Journal of Dietary Supplements · doi:10.1080/19390211.2016.1275917 · Cited by 44 · see citing works
Sinha, S., Patro, N., & Patro, I. K. (2020) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.08.181 · Cited by 39 · see citing works
Microalgae as a potential therapeutic drug candidate for neurodegenerative diseases
Parameswari, R. P., & Thangavelu, L. P. (2022) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2022.09.009 · Cited by 38 · see citing works
Tamtaji, O. R., Heidari‐Soureshjani, R., Asemi, Z., & Kouchaki, E. (2023) · Phytotherapy Research · doi:10.1002/ptr.7791 · Cited by 35 · see citing works
Park, H.-J., & Lee, H.-S. (2016) · Nutrition Research and Practice · doi:10.4162/nrp.2016.10.4.418 · Cited by 34 · see citing works
Dimopoulou, M., Kolonas, A., Stagos, D., & Gortzi, O. (2025) · Biomass · doi:10.3390/biomass5010011 · Cited by 34 · see citing works
El‐Atrsh, A., Tousson, E., Elnahas, E. E., Massoud, A. A., & Al-Zubaidi, M. (2019) · HAL · Cited by 34 · see citing works
Daily Feeding of Fructooligosaccharide or Glucomannan Delays Onset of Senescence in SAMP8 Mice
NAKAMURA, S., Kondo, N., Yamaguchi, Y., Hashiguchi, M., Tanabe, K., Ushiroda, C., Kawahashi-Tokuhisa, M., Yui, K., Miyakoda, M., & Oku, T. (2014) · Gastroenterology Research and Practice · doi:10.1155/2014/303184 · Cited by 32 · see citing works
Spirulina (Arthrospira platensis): Antiallergic Agent or Hidden Allergen? A Literature Review
Gromek, W., Kołdej, N., Kurowski, M. M., & Majsiak, E. (2024) · Foods · doi:10.3390/foods13071052 · Cited by 32 · see citing works
Combination of Spirulina with glycyrrhizin prevents cognitive dysfunction in aged obese rats
Subramanian, S., & Madhavadas, S. (2015) · Indian Journal of Pharmacology · doi:10.4103/0253-7613.150327 · Cited by 26 · see citing works
Chan, Y., Lee, I., Wang, M.-F., Yeh, W.-C., & Liang, B.-C. (2018) · Journal of Functional Foods · doi:10.1016/j.jff.2018.09.023 · Cited by 26 · see citing works
Self-citationCastañeda, A., Ferraz, R., Vieira, M., Cardoso, I., Vasconcelos, V. M., & Martins, R. F. (2021) · Marine Drugs · doi:10.3390/md19060343 · Cited by 24 · see citing works
Argüelles, N., Álvarez‐González, I., Madrigal‐Bujaidar, E., & Chamorro, G. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/604535 · Cited by 24 · see citing works
Prabhu, S., Kalaimathi, K., Jayasree, S., Ayyanar, M., Kadaikunnan, S., Thiruvengadam, M., Amalraj, S., Ceasar, S. A., Alharbi, N. S. H. A., Sanjeevi, S. B., et al. (2024) · Journal of Computational Biophysics and Chemistry · doi:10.1142/s2737416524500133 · Cited by 23 · see citing works
Ghanbari, A., Vafaei, A. A., Nasab, F. S. N., Attarmoghaddam, M., Bandegi, A. R., & Moradikor, N. (2019) · South African Journal of Botany · doi:10.1016/j.sajb.2019.08.045 · Cited by 20 · see citing works
Zhou, T., Liu, Y., Wang, Q., Dou, Q., Li, X., Pan, Y., Meng, L., & Xue, T. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104706 · Cited by 20 · see citing works
Okuyama, S., Kotani, Y., Yamamoto, K., Sawamoto, A., Sugawara, K., Sudo, M., Ohkubo, Y., Tamanaha, A., Nakajima, M., & Furukawa, Y. (2018) · Bioscience Biotechnology and Biochemistry · doi:10.1080/09168451.2018.1433993 · Cited by 20 · see citing works
Thangsiri, S., Inthachat, W., Temviriyanukul, P., Sahasakul, Y., Trisonthi, P., Pan-utai, W., Siriwan, D., & Suttisansanee, U. (2024) · Scientific Reports · doi:10.1038/s41598-024-74492-4 · Cited by 17 · see citing works
Hwang, J.-H., Chang, N.-C., Chen, J.-C., & Chan, Y. (2015) · Audiology and Neurotology · doi:10.1159/000381934 · Cited by 15 · see citing works
Self-citationChan, Y., & Hwang, J.-H. (2017) · PLoS ONE · doi:10.1371/journal.pone.0178916 · Cited by 13 · see citing works
Self-citationAssociation of periodic limb movements during sleep and Parkinson disease
Hwang, S.-R., Hwang, S.-W., Chen, J.-C., & Hwang, J.-H. (2019) · Medicine · doi:10.1097/md.0000000000018444 · Cited by 12 · see citing works
Self-citationAbdelghany, A. K., Fouad, A. G., Abdel‐Wahab, A., Abdel‐Razik, A. H., El‐Samannoudy, S. I., Ibrahim, M. A., Hassan, W. H., & El‐Ela, F. I. A. (2023) · Drug Delivery and Translational Research · doi:10.1007/s13346-023-01301-2 · Cited by 12 · see citing works
RetractedChan, Y., Wu, C.-S., Wu, T.-C., Lin, Y.-H., & Chang, S.-J. (2019) · Nutrients · doi:10.3390/nu11071631 · Cited by 12 · see citing works
Self-citationBrito, A. D. F., Silva, A. S., de Souza, A. A., Ferreira, P. B., de Souza, I. L. L., Araujo, L. C. D. C., Félix, G. D. S., Sampaio, R. D. S., Silva, M. D. C. C., Tavares, R. L., et al. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/7838149 · Cited by 12 · see citing works
EFFECT OF SPIRULINA PLATENSIS ON REPRODUCTIVE PERFORMANCE OF RABBIT BUCKS
Fouda, S. F., & Ismail, R. F. S. A. (2017) · Egyptian Journal of Nutrition and Feeds · doi:10.21608/ejnf.2017.75118 · Cited by 12 · see citing works
Mazzola, D., Fornari, F., Viganó, G. S., Oro, T., Costa, J. A. V., & Bertolin, T. E. (2015) · Brazilian Archives of Biology and Technology · doi:10.1590/s1516-89132015060216 · Cited by 11 · see citing works
Chu, W.-L., Quynh, L. V., & Radhakrishnan, A. K. (2013) · Journal of Dietary Supplements · doi:10.3109/19390211.2013.822452 · Cited by 11 · see citing works
El-Ratel, I. T. (2020) · Egyptian Poultry Science · doi:10.21608/epsj.2020.81017 · Cited by 10 · see citing works
Luo, Y.-C., & Jing, P. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218207 · Cited by 9 · see citing works
Hwang, J.-H., & Chan, Y. (2016) · BMC Neurology · doi:10.1186/s12883-016-0682-4 · Cited by 8 · see citing works
Self-citationNg, C. L., Tan, G. C., Yow, Y., Gupta, M. K., & Kwong, P. J. (2021) · Asian Pacific Journal of Tropical Medicine · doi:10.4103/1995-7645.304299 · Cited by 5 · see citing works
Bo, X. (2025) · The EPMA Journal · doi:10.1007/s13167-025-00405-8 · Cited by 4 · see citing works
Elgendy, A., Elgendy, E., & Saaddoun, M. (2024) · Egyptian Dental Journal /Egyptian Dental Journal · doi:10.21608/edj.2023.249368.2785 · Cited by 4 · see citing works
Spirulina: An Emerging Treatment Modality for the Management of Oral Submucous Fibrosis
Desai, K. M., Hallikerimath, S. R., & Kale, A. D. (2017) · International Journal of Oral Care & Research · doi:10.5005/jp-journals-10051-0125 · Cited by 4 · see citing works
Neuroprotective potential of marine algal antioxidants
Nyiew, K.-Y., Ngu, E.-L., Wong, K.-H., Goh, B. H., & Yow, Y. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95086-2.00030-8 · Cited by 3 · see citing works
Transgenerational beneficial effect of Arthrospira (Spirulina) platensis on the rabbit ovaries
Abadjieva, D. V., Юозапович, Ш. А., Shimkiene, A., Rashev, P. I., & Kistanova, E. K. (2018) · Journal of Applied Phycology · doi:10.1007/s10811-018-1400-y · Cited by 3 · see citing works
The Cytokines-Directed Roles of Spirulina for Radioprotection of Lacrimal Gland
Atılgan, H. İ., Akbulut, A., Yazıhan, N., Yumuşak, N., Şıngar, E., Koca, G., & Korkmaz, M. (2022) · Ocular Immunology and Inflammation · doi:10.1080/09273948.2022.2026409 · Cited by 3 · see citing works
Donen, A., Lifschytz, T., Wolf, G., Ben-Ari, H., Lotan, A., Lerer, L. B., & Lerer, B. (2021) · The Natural Products Journal · doi:10.2174/2210315512666211224102922 · Cited by 3 · see citing works
Abdelhafez, H., Eid, F. A., Zahkouk, S. A., & El-Wahsh, A. M. S. E.-D. A. (2019) · The Egyptian Journal of Hospital Medicine · doi:10.21608/ejhm.2019.55488 · Cited by 3 · see citing works
Andrade, G., Labarca, T. F., Llanca, V., Morales, P., Sabando, K., & Ortuño, D. (2023) · Research Square · doi:10.21203/rs.3.rs-2539298/v1 · Cited by 3 · see citing works
Nutritional Support System (NSS) as a New Therapeutic Strategy for Cerebral Palsy
Leal-Martínez, F., Ramirez, G. J., & Ibarra, A. (2023) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527322666230330124124 · Cited by 2 · see citing works
Boukari, O., Khemissi, W., Ghodbane, S., Lahbib, A., Tebourbi, O., Rhouma, K. B., Sakly, M., & Hallègue, D. (2023) · Archivio Italiano di Urologia e Andrologia · doi:10.4081/aiua.2023.11593 · Cited by 2 · see citing works
Oxy+ (arthrospira) and its medicinal importance: an appraisal
Alam, M. A., Quamri, M. A., Bhat, M. D. A., Aafreen, S., & Sofi, G. (2020) · Drug Metabolism and Personalized Therapy · doi:10.1515/dmpt-2020-0152 · Cited by 2 · see citing works
Oxy+ (arthrospira) and its medicinal importance: an appraisal
Alam, M. A., Quamri, M. A., Bhat, M. D. A., Aafreen, S., & Sofi, G. (2020) · Drug Metabolism and Personalized Therapy · doi:10.1515/dmdi-2020-0152 · Cited by 3 · see citing works
Chan, Y., Lin, M.-H., & Hwang, J.-H. (2020) · Research Square · doi:10.21203/rs.3.rs-61504/v1
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Babicz, M., & Kropiwiec-Domańska, K. (2022) · doi:10.24326/mon.2022.8
Purba, H. H. S., Paramita, R., Prijanti, A. R., & Iswanti, F. C. (2023) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/1271/1/012081
Srivastava, A. N., Siddiqi, Z., Siddiqui, S., & Ahmad, R. (2026) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/0118715206383642251105064036
AChE inhibitors from marine resources
Kim, C. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-45844-6.00018-4
Taheri, A. T., Motamedzadeh, A., Zahedi, E., Farasat, A., Dadgostar, E., Aschner, M., Khanifar, H., Rahmati‐Dehkordi, F., & Tamtaji, O. R. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-12532-0 · Cited by 1 · see citing works
- Authors
- HWANG, J.-H., LEE, I.-T., JENG, K.-C., WANG, M.-F., HOU, R. C.-W., WU, S.-M., & CHAN, Y.-C.
- Affiliations
- Tzu Chi University (TW)
- Taichung Veterans General Hospital (TW)
- National Chung Hsing University (TW)
- Providence University (TW)
- Yuanpei University (TW)
- Venue
- Journal of Nutritional Science and Vitaminology
- Published
- 2011
- Volume
- 57
- Issue
- 2
- Pages
- 186-191
- ISSN
- 0301-4800 (ISSN-L)
- 1881-7742
- OpenAlex
- W2139144658
- Cited by
- 71
- References
- 29
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 4 · 2023: 8 · 2022: 5 · 2021: 7 · 2020: 7 · 2019: 8 · 2018: 6 · 2017: 4 · 2016: 4 · 2015: 7 · 2014: 1 · 2013: 4 · 2012: 1
- FWCI
- 0.79
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Journal of Nutritional Science and Vitaminology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Council
- Taichung Veterans General Hospital
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Antioxidants, Aging, Portulaca oleracea
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
- Keywords
- Spirulina platensis, memory impairment, oxidative stress, antioxidant enzymes, amyloid-beta, SAMP8 mice, senescence-accelerated mice, lipid peroxidation, catalase, glutathione peroxidase, superoxide dismutase, dietary supplementation, neuroprotection
- MeSH terms
- Aging, Animals, Antioxidants, Brain, Male, Phytotherapy, Memory, Memory Disorders, Mice, Inbred Strains, Random Allocation, Lipid Peroxidation, Amyloid beta-Peptides, Oxidative Stress, Dietary Supplements, Plant Preparations, Mice, Spirulina
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