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Flavonoids as Prospective Neuroprotectants and Their Therapeutic Propensity in Aging Associated Neurological Disorders

Ayaz, Muhammad, Sadiq, Abdul, Junaid, Muhammad, Ullah, Farhat, Ovais, Muhammad, Ullah, Ikram, Ahmed, Jawad, Shahid, Muhammad·2019·Frontiers in Aging Neuroscience
DOI 10.3389/fnagi.2019.00155PMC PMC6606780
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  • Fine-tuning of MEK/ERK pathway activation by natural bioactive compounds, such as flavonoids, appears to promote physiological responses of gene transcription/translation and cell growth/survival and, in turn, advance human health as neuroprotectants and cognitive enhancers.

    “Although sustained hyperactivation of MEK/ERK signaling is a prerequisite for malignant transformation or progression, the fine-tuning of this pathway activation by natural bioactive compounds, such as flavonoids, appears to promote physiological responses of gene transcription/translation and cell growth/survival and, in turn, advance human health as neuroprotectants and cognitive enhancers.48–51”

    From TERT activation targets DNA methylation and multiple aging hallmarks (2024) · cites this paper as [51]

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Cited by

Sorted by citations

Metadata

Authors
Ayaz, M., Sadiq, A., Junaid, M., Ullah, F., Ovais, M., Ullah, I., Ahmed, J., & Shahid, M.
Venue
Frontiers in Aging Neuroscience
Publisher
Frontiers Media SA
Published
2019-06-26
Volume
11
ISSN
1663-4365
DOI
10.3389/fnagi.2019.00155
PMC
PMC6606780
Cited by
320
References
10
Licence
creativecommons.org/licenses/by/4.0/ (vor)

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