Melatonin: A Mitochondrial Targeting Molecule Involving Mitochondrial Protection and Dynamics

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

Uttara, B., Singh, A., Zamboni, P., & Mahajan, R. (2009) · Current Neuropharmacology · doi:10.2174/157015909787602823 · Cited by 3,378 · see citing works

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

REITER, R. J. (1991) · Endocrine Reviews · doi:10.1210/edrv-12-2-151 · Cited by 2,192 · see citing works

Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells

Smirnova, E., Griparić, L., Shurland, D., & van der Bliek, A. M. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.8.2245 · Cited by 1,938 · see citing works

On the origin of mitosing cells

Sagan, L. (1967) · Journal of Theoretical Biology · doi:10.1016/0022-5193(67)90079-3 · Cited by 1,870 · see citing works

Melatonin as an antioxidant: under promises but over delivers

Reiter, R. J., Mayo, J. C., Tan, D. X., Sainz, R. M., Alatorre-Jiménez, M. A., & Qin, L. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12360 · Cited by 1,741 · see citing works

Melatonin : a potent, endogenous hydroxyl radical scavenger

Tan, D. (1993) · Endocrine Journal · Cited by 1,659 · see citing works

One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?

Tan, D., Manchester, L. C., Terron, M. P., Flores, L. J., & Reiter, R. J. (2007) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2006.00407.x · Cited by 1,601 · see citing works

The Haber–Weiss reaction and mechanisms of toxicity

Kehrer, J. P. (2000) · Toxicology · doi:10.1016/s0300-483x(00)00231-6 · Cited by 1,418 · see citing works

Mitochondrial dynamics and apoptosis

Suen, D.-F., Norris, K. L., & Youle, R. J. (2008) · Genes & Development · doi:10.1101/gad.1658508 · Cited by 1,270 · see citing works

Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells

Kelso, G. F., Porteous, C. M., Coulter, C. V., Hughes, G., Porteous, W. K., Ledgerwood, E. C., Smith, R. A. J., & Murphy, M. P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009093200 · Cited by 1,091 · see citing works

Extrapineal melatonin: sources, regulation, and potential functions

Acuña-Castroviejo, D., Escames, G., Venegas, C., Díaz-Casado, M. E., Lima‐Cabello, E., López, L. C., Rosales‐Corral, S., Tan, D., & Reiter, R. J. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1579-2 · Cited by 1,086 · see citing works

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

Manchester, L. C., Coto‐Montes, A. M., Boga, J. A., Andersen, L. P. H., Zhou, Z., Galano, A., Vriend, J. P., Tan, D. X., & Reiter, R. J. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12267 · Cited by 954 · see citing works

Functions of melatonin in plants: a review

Arnao, M. B., & Hernández‐Ruíz, J. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12253 · Cited by 893 · see citing works

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

Galano, A., Tan, D. X., & Reiter, R. J. (2012) · Journal of Pineal Research · doi:10.1111/jpi.12010 · Cited by 829 · see citing works

Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism

Tan, D.-X., Manchester, L., Esteban-Zubero, E., Zhou, Z., & Reiter, R. (2015) · Molecules · doi:10.3390/molecules201018886 · Cited by 719 · see citing works

Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes

Cai, L., Sutter, B. M., Li, B., & Tu, B. P. (2011) · Molecular Cell · doi:10.1016/j.molcel.2011.05.004 · Cited by 701 · see citing works

Antioxidative Protection by Melatonin: Multiplicity of Mechanisms from Radical Detoxification to Radical Avoidance

Hardeland, R. (2005) · Endocrine · doi:10.1385/endo:27:2:119 · Cited by 670 · see citing works

Melatonin enhances plant growth and abiotic stress tolerance in soybean plants

Wei, W., Li, Q., Chu, Y.-N., Reiter, R. J., Yu, X.-M., Zhu, D.-H., Zhang, W., Ma, B., Lin, Q. F., Zhang, J.-S., et al. (2014) · Journal of Experimental Botany · doi:10.1093/jxb/eru392 · Cited by 660 · see citing works

Melatonin: Exceeding Expectations

Reiter, R. J., Tan, D. X., & Galano, A. (2014) · Physiology · doi:10.1152/physiol.00011.2014 · Cited by 610 · see citing works

Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes

Tan, D. X., Manchester, L. C., Liu, X., Rosales‐Corral, S., Acuña-Castroviejo, D., & Reiter, R. J. (2012) · Journal of Pineal Research · doi:10.1111/jpi.12026 · Cited by 584 · see citing works

Extrapineal melatonin: analysis of its subcellular distribution and daily fluctuations

Venegas, C., García, J. A. G., Escames, G., Ortiz, F., López, A., Doerrier, C., García‐Corzo, L., López, L. C., Reiter, R. J., & Acuña-Castroviejo, D. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00931.x · Cited by 580 · see citing works

Significance of Melatonin in Antioxidative Defense System: Reactions and Products

Tan, D., Manchester, L. C., Reiter, R. J., Qi, W., Karbownik‐Lewińska, M., & Calvo, J. R. (2000) · Neurosignals · doi:10.1159/000014635 · Cited by 566 · see citing works

Animal and human studies with the mitochondria‐targeted antioxidant MitoQ

Smith, R. A. J., & Murphy, M. P. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05627.x · Cited by 553 · see citing works

Melatonin mediates the regulation of ABA metabolism, free-radical scavenging, and stomatal behaviour in two Malus species under drought stress

Li, C., Tan, D., Liang, D., Chang, C., Jia, D., & Ma, F. (2014) · Journal of Experimental Botany · doi:10.1093/jxb/eru476 · Cited by 544 · see citing works

Mitochondrial biogenesis and dynamics in the developing and diseased heart

Dorn, G. W., Vega, R. B., & Kelly, D. P. (2015) · Genes & Development · doi:10.1101/gad.269894.115 · Cited by 470 · see citing works

Mitochondria‐targeted antioxidants

Oyewole, A. O., & Birch‐Machin, M. A. (2015) · The FASEB Journal · doi:10.1096/fj.15-275404 · Cited by 467 · see citing works

Selective targeting of an antioxidant to mitochondria

Smith, R. A. J., Porteous, C. M., Coulter, C. V., & Murphy, M. P. (1999) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1999.00543.x · Cited by 466 · see citing works

Hydroxyl Radical and Its Scavengers in Health and Disease

Lipiński, B. (2011) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2011/809696 · Cited by 457 · see citing works

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling

Hardeland, R., Madrid, J. A., Tan, D. X., & Reiter, R. J. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00934.x · Cited by 449 · see citing works

The significance of the metabolism of the neurohormone melatonin: Antioxidative protection and formation of bioactive substances

Hardeland, R., Reiter, R. J., Pöeggeler, B., & Tan, D. X. (1993) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80016-8 · Cited by 424 · see citing works

Melatonin, mitochondria, and cellular bioenergetics

Acuña-Castroviejo, D., Martı́n, M., Macías, M. J., Escames, G., León, J., Khaldy, H., & Reiter, R. J. (2001) · Journal of Pineal Research · doi:10.1034/j.1600-079x.2001.300201.x · Cited by 401 · see citing works

Non‐vertebrate melatonin

Hardeland, R., & Pöeggeler, B. (2003) · Journal of Pineal Research · doi:10.1034/j.1600-079x.2003.00040.x · Cited by 400 · see citing works

Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

Elrod, J. W., Wong, R., Mishra, S., Vagnozzi, R. J., Sakthievel, B., Goonasekera, S. A., Karch, J., Gabel, S., Farber, J., Force, T., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci43171 · Cited by 384 · see citing works

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

Paradies, G., Petrosillo, G., Paradies, V., Reiter, R. J., & Ruggiero, F. M. (2010) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2010.00759.x · Cited by 378 · see citing works

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

Jin, H., Kanthasamy, A., Ghosh, A., Anantharam, V., Kalyanaraman, B., & Kanthasamy, A. G. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.09.007 · Cited by 362 · see citing works

Melatonin but not vitamins C and E maintains glutathione homeostasis in t‐butyl hydroperoxide‐induced mitochondrial oxidative stress

Martı́n, M., Macías, M. J., Escames, G., León, J., & Acuña-Castroviejo, D. (2000) · The FASEB Journal · doi:10.1096/fj.99-0865fje · Cited by 347 · see citing works

Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity

Tan, D. ‐., Manchester, L. C., Fuentes‐Broto, L., Paredes, S. D., & Reiter, R. J. (2010) · Obesity Reviews · doi:10.1111/j.1467-789x.2010.00756.x · Cited by 343 · see citing works

Calcium Homeostasis and Organelle Function in the Pathogenesis of Obesity and Diabetes

Arruda, A. P., & Hotamışlıgil, G. S. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.06.010 · Cited by 338 · see citing works

A Genome Phylogeny for Mitochondria Among  -Proteobacteria and a Predominantly Eubacterial Ancestry of Yeast Nuclear Genes

Esser, C. (2004) · Molecular Biology and Evolution · doi:10.1093/molbev/msh160 · Cited by 324 · see citing works

Antioxidants that protect mitochondria reduce interleukin-6 and oxidative stress, improve mitochondrial function, and reduce biochemical markers of organ dysfunction in a rat model of acute sepsis

Lowes, D. A., Webster, N. R., Murphy, M. P., & Galley, H. F. (2013) · British Journal of Anaesthesia · doi:10.1093/bja/aes577 · Cited by 314 · see citing works

Melatonin‐induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo

Martı́n, M., Macías, M., Escames, G., Reiter, R. J., Agapito, M. T., Ortíz, G. G., & Acuña-Castroviejo, D. (2000) · Journal of Pineal Research · doi:10.1034/j.1600-079x.2000.280407.x · Cited by 295 · see citing works

On the significance of an alternate pathway of melatonin synthesis via 5‐methoxytryptamine: comparisons across species

Tan, D. X., Hardeland, R., Back, K., Manchester, L. C., Alatorre-Jiménez, M. A., & Reiter, R. J. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12336 · Cited by 282 · see citing works

Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production

López, A., García, J. A., Escames, G., Venegas, C., Ortiz, F., López, L. C., & Acuña-Castroviejo, D. (2008) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2008.00647.x · Cited by 277 · see citing works

Melatonin enhances thermotolerance by promoting cellular protein protection in tomato plants

Xu, W., Cai, S., Zhang, Y., Wang, Y., Ahammed, G. J., Xia, X., Shi, K., Zhou, Y., Yu, J., Reiter, R. J., et al. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12359 · Cited by 273 · see citing works

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

Weinert, B. T., Iešmantavičius, V., Moustafa, T., Scholz, C. W., Wagner, S., Magnes, C., Zechner, R., & Choudhary, C. (2014) · Molecular Systems Biology · doi:10.1002/msb.134766 · Cited by 272 · see citing works

Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress‐induced apoptosis of rat brain astrocytes

Jou, M., Peng, T., Reiter, R. J., Jou, S., WU, H., & Wen, S. (2004) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2004.00140.x · Cited by 265 · see citing works

Role of hydrogen peroxide and oxidative stress in healing responses

Rojkind, M., Domı́nguez-Rosales, J. A., Nieto, N., & Greenwel, P. (2002) · Cellular and Molecular Life Sciences · doi:10.1007/pl00012511 · Cited by 264 · see citing works

Melatonin as a signal molecule triggering defense responses against pathogen attack in Arabidopsis and tobacco

Lee, H. Y., Byeon, Y., & Back, K. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12165 · Cited by 264 · see citing works

Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins

Neufeld-Cohen, A., Robles, M. S., Aviram, R., Manella, G., Adamovich, Y., Ladeuix, B., Nir, D., Rousso-Noori, L., Kuperman, Y., Golik, M., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1519650113 · Cited by 262 · see citing works

Melatonin increases the activity of the oxidative phosphorylation enzymes and the production of ATP in rat brain and liver mitochondria

Martı́n, M., Macías, M. J., León, J., Escames, G., Khaldy, H., & Acuña-Castroviejo, D. (2002) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(01)00138-8 · Cited by 261 · see citing works

Melatonin protects against common deletion of mitochondrial DNA‐augmented mitochondrial oxidative stress and apoptosis

Jou, M., Peng, T.-I., Yu, P., Jou, S., Reiter, R. J., Chen, J., WU, H., Chen, C., & Hsu, L. (2007) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2007.00490.x · Cited by 258 · see citing works

Melatonin in Plants – Diversity of Levels and Multiplicity of Functions

Hardeland, R. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00198 · Cited by 256 · see citing works

Mitochondrial dynamics during cell cycling

Horbay, R., & Bilyy, R. O. (2016) · APOPTOSIS · doi:10.1007/s10495-016-1295-5 · Cited by 246 · see citing works

Melatonin-mitochondria Interplay in Health and Disease

Acuña-Castroviejo, D., López, L. C., Escames, G., López, A., García, J. A., & Reiter, R. J. (2011) · Current Topics in Medicinal Chemistry · doi:10.2174/156802611794863517 · Cited by 245 · see citing works

Arabidopsis serotonin N ‐acetyltransferase knockout mutant plants exhibit decreased melatonin and salicylic acid levels resulting in susceptibility to an avirulent pathogen

Lee, H. Y., Byeon, Y., Tan, D. X., Reiter, R. J., & Back, K. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12214 · Cited by 243 · see citing works

Is multiple sclerosis a mitochondrial disease?

Mao, P., & Reddy, P. H. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2009.07.002 · Cited by 242 · see citing works

Melatonin prevents cell death and mitochondrial dysfunction via a SIRT 1‐dependent mechanism during ischemic‐stroke in mice

Yang, Y., Jiang, S., Dong, Y., Fan, C., Zhao, L., Yang, X., Li, J., Di, S., Yue, L., Liang, G., et al. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12193 · Cited by 239 · see citing works

Mitochondria in White, Brown, and Beige Adipocytes

Čedíková, M., Kripnerová, M., Dvořáková, J., Pitule, P., Grundmanova, M., Babuška, V., Müllerová, D., & Kuncová, J. (2016) · Stem Cells International · doi:10.1155/2016/6067349 · Cited by 237 · see citing works

JAK 2/ STAT 3 activation by melatonin attenuates the mitochondrial oxidative damage induced by myocardial ischemia/reperfusion injury

Yang, Y., Duan, W., Jin, Z., Yi, W., Yan, J., Zhang, S., Wang, N., Liang, Z., Li, Y., Chen, W., et al. (2013) · Journal of Pineal Research · doi:10.1111/jpi.12070 · Cited by 232 · see citing works

Melatonin enhances mitophagy and mitochondrial biogenesis in rats with carbon tetrachloride‐induced liver fibrosis

Kang, J., Hong, J., & Lee, S. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12319 · Cited by 231 · see citing works

Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism

Ding, K., Wang, H., Xu, J., Li, T., Zhang, L., Ding, Y., Zhu, L., He, J., & Zhou, M. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.04.031 · Cited by 228 · see citing works

Mitochondria Synthesize Melatonin to Ameliorate Its Function and Improve Mice Oocyte’s Quality under in Vitro Conditions

He, C., Wang, J., Zhang, Z., Yang, M., Li, Y., Tian, X., Ma, T., Tao, J., Zhu, K., Song, Y., et al. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17060939 · Cited by 226 · see citing works

The interaction of melatonin and its precursors with aluminium, cadmium, copper, iron, lead, and zinc: An adsorptive voltammetric study

Limson, J. L., Nyokong, T., & Daya, S. (1998) · Journal of Pineal Research · doi:10.1111/j.1600-079x.1998.tb00361.x · Cited by 224 · see citing works

An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice

Mansouri, A., Gaou, I., de Kerguenec, C., Amsellem, S., Haouzi, D., Berson, A., Moreau, A., Feldmann, G., Lettéron, P., Pessayre, D., et al. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70566-4 · Cited by 208 · see citing works

Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis

Galano, A., Medina, M. E., Tan, D. X., & Reiter, R. J. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12196 · Cited by 200 · see citing works

On the direct scavenging activity of melatonin towards hydroxyl and a series of peroxyl radicals

Galano, A. (2011) · Physical Chemistry Chemical Physics · doi:10.1039/c0cp02801k · Cited by 196 · see citing works

Melatonin counteracts lipopolysaccharide‐induced expression and activity of mitochondrial nitric oxide synthase in rats

Escames, G., León, J., Macías, M. J., Khaldy, H., & Acuña-Castroviejo, D. (2003) · The FASEB Journal · doi:10.1096/fj.02-0692fje · Cited by 191 · see citing works

Melatonin induces browning of inguinal white adipose tissue in Zucker diabetic fatty rats

Jiménez‐Aranda, A., Fernández‐Vázquez, G., Campos, D., Tassi, M., Velasco‐Perez, L., Tan, D. X., Reiter, R. J., & Agil, A. (2013) · Journal of Pineal Research · doi:10.1111/jpi.12089 · Cited by 189 · see citing works

Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: relation to their biological functions.

Tan, D.-X., Zheng, X., Kong, J., Manchester, L., Hardeland, R., Kim, S., Xu, X., & Reiter, R. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms150915858 · Cited by 188 · see citing works

The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity

Wang, X., Sirianni, A. C., Pei, Z., Cormier, K., Smith, K., Jiang, J., Zhou, S., Wang, H., Zhao, R., Yano, H., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.3059-11.2011 · Cited by 186 · see citing works

Melatonin treatment restores mitochondrial function in Alzheimer’s mice: a mitochondrial protective role of melatonin membrane receptor signaling

Dragicevic, N., Copes, N., O’Neal-Moffitt, G., Jin, J., Buzzeo, R. W., Mamcarz, M., Tan, J., Cao, C., Olcese, J., Arendash, G. W., et al. (2011) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2011.00864.x · Cited by 185 · see citing works

Melatonin‐enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage

Chen, J., Wang, L., Wu, C., Hu, Q., Gu, C., Yan, F., Li, J., Yan, W. X., & Chen, G. (2013) · Journal of Pineal Research · doi:10.1111/jpi.12086 · Cited by 183 · see citing works

Cardiolipin and mitochondrial carriers

Klingenberg, M. (2009) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2009.06.007 · Cited by 181 · see citing works

Melatonin modulates TLR4‐mediated inflammatory genes through MyD88‐ and TRIF‐dependent signaling pathways in lipopolysaccharide‐stimulated RAW264.7 cells

Xia, M., Liang, Y., Wang, H., Chen, X., Huang, Y., Zhang, Z., Chen, Y., Zhang, C., Zhao, M., Xu, D., et al. (2012) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2012.01002.x · Cited by 175 · see citing works

Cellular localization and kinetics of the rice melatonin biosynthetic enzymes SNAT and ASMT

Byeon, Y., Lee, H. Y., Lee, K., Park, S.-K., & Back, K. (2013) · Journal of Pineal Research · doi:10.1111/jpi.12103 · Cited by 175 · see citing works

Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease

Quintanilla, R. A., & Johnson, G. V. W. (2009) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2009.07.010 · Cited by 173 · see citing works

Beneficial effects of melatonin on bovine oocytes maturation: a mechanistic approach

Tian, X., Wang, F., He, C., Zhang, L., Tan, D. X., Reiter, R. J., Xu, J., Ji, P., & Liu, G. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12163 · Cited by 172 · see citing works

Melatonin attenuates traumatic brain injury‐induced inflammation: a possible role for mitophagy

Lin, C., Chao, H., Li, Z., Xu, X., Liu, Y., Hou, L.-J., Liu, N., & Ji, J. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12337 · Cited by 169 · see citing works

Melatonin inhibits apoptosis and improves the developmental potential of vitrified bovine oocytes

Zhao, X., Hao, H., Du, W., Zhao, S., Wang, H., Wang, N., Wang, D., Liu, Y., Qin, T., & Zhu, H. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12290 · Cited by 167 · see citing works

Melatonin, Mitochondrial Homeostasis and Mitochondrial-Related Diseases

Acuña-Castroviejo, D., Escames, G., Carazo, Á., León, J., Khaldy, H., & Reiter, R. J. (2002) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026023394344 · Cited by 166 · see citing works

Melatonin immunoreactivity in the photosynthetic prokaryote Rhodospirillum rubrum: implications for an ancient antioxidant system.

Manchester, L. C., Pöeggeler, B., Alvares, F. L., Ogden, G. B., & Reiter, R. J. (1995) · PubMed · Cited by 165 · see citing works

Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces

Reiter, R. J., Tan, D. X., Kim, S. J., & Cruz, M. H. C. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0719-7 · Cited by 163 · see citing works

Melatonin in plants and other phototrophs: advances and gaps concerning the diversity of functions

Hardeland, R. (2014) · Journal of Experimental Botany · doi:10.1093/jxb/eru386 · Cited by 160 · see citing works

Melatonin reduces lipid peroxidation and membrane viscosity

Reiter, R. J., Tan, D., & Galano, A. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00377 · Cited by 154 · see citing works

Attenuation of cardiac mitochondrial dysfunction by melatonin in septic mice

Escames, G., López, L. C., Ortiz, F., López, A., García, J. A. G., Ros, E., & Acuña-Castroviejo, D. (2007) · FEBS Journal · doi:10.1111/j.1742-4658.2007.05755.x · Cited by 148 · see citing works

Protective effects of melatonin and mitochondria-targeted antioxidants against oxidative stress: A review

Ramis, M., Esteban, S., Miralles, A., Tan, D.-X., & Reiter, R. (2015) · Current Medicinal Chemistry · doi:10.2174/0929867322666150619104143 · Cited by 146 · see citing works

Role of melatonin in the regulation of autophagy and mitophagy: A review

Coto‐Montes, A. M., Boga, J. A., Rosales‐Corral, S., Fuentes‐Broto, L., Tan, D., & Reiter, R. J. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2012.04.009 · Cited by 144 · see citing works

Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer

Hevia, D., González‐Menéndez, P., Quirós-González, I., Miar, A., Rodríguez‐García, A., Tan, D. X., Reiter, R. J., Mayo, J. C., & Sainz, R. M. (2015) · Journal of Pineal Research · doi:10.1111/jpi.12210 · Cited by 144 · see citing works

Melatonin prevents abnormal mitochondrial dynamics resulting from the neurotoxicity of cadmium by blocking calcium‐dependent translocation of Drp1 to the mitochondria

Xu, S., Pi, H., Zhang, L., Zhang, N.-X., Li, Y., Zhang, H., Tang, J., Li, H., Feng, M., Deng, P., et al. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12310 · Cited by 139 · see citing works

Melatonin resynchronizes dysregulated circadian rhythm circuitry in human prostate cancer cells

Jung-Hynes, B. D., Huang, W., Reiter, R. J., & Ahmad, N. (2010) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2010.00767.x · Cited by 137 · see citing works

Long‐term melatonin administration protects brain mitochondria from aging

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Melatonin‐induced increase in sensitivity of human hepatocellular carcinoma cells to sorafenib is associated with reactive oxygen species production and mitophagy

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Circadian Rhythms of Melatonin, Cortisol, and Clock Gene Expression During Simulated Night Shift Work

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Melatonin protects against rotenone‐induced oxidative stress in a hemiparkinsonian rat model

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Melatonin controlled apoptosis and protected the testes and sperm quality against bisphenol A-induced oxidative toxicity

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Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation

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Alterations in mitochondrial respiratory functions, redox metabolism and apoptosis by oxidant 4-hydroxynonenal and antioxidants curcumin and melatonin in PC12 cells

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Mitochondrial oxidative metabolism and uncoupling proteins in the failing heart

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How did life survive Earth's great oxygenation?

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A Circadian Clock Entrained by Melatonin Is Ticking in the Rat Fetal Adrenal

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Melatonin in Arabidopsis thaliana acts as plant growth regulator at low concentrations and preserves seed viability at high concentrations

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Glia-Pinealocyte Network: The Paracrine Modulation of Melatonin Synthesis by Tumor Necrosis Factor (TNF)

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The melatonin metabolite N1‐acetyl‐5‐methoxykynuramine is a potent singlet oxygen scavenger

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Melatonin production in an aerobic photosynthetic bacterium: An evolutionarily early association with darkness

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Melatonin and its brain metabolite N1‐acetyl‐5‐methoxykynuramine prevent mitochondrial nitric oxide synthase induction in parkinsonian mice

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Melatonin modulated autophagy and Nrf2 signaling pathways in mice with colitis‐associated colon carcinogenesis

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A Novel Metabolic Pathway of Melatonin: Oxidation by Cytochromec

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Melatonin reduces apoptosis and necrosis induced by ischemia/reperfusion injury of the pancreas

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Predominance of 2‐hydroxymelatonin over melatonin in plants

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Melatonin protects against Nickel-induced neurotoxicity in vitro by reducing oxidative stress and maintaining mitochondrial function

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Scavenging effect of melatonin on hydroxyl radicals generated by alloxan

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Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice

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The rat oocyte synthesises melatonin

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2‐Hydroxymelatonin promotes the resistance of rice plant to multiple simultaneous abiotic stresses (combined cold and drought)

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Melatonin enhances the occurrence of autophagy induced by oxidative stress in Arabidopsis seedlings

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Cyclic-3-hydroxymelatonin (C3HOM), A Potent Antioxidant, Scavenges Free Radicals and Suppresses Oxidative Reactions

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Protective effect of melatonin‐supported adipose‐derived mesenchymal stem cells against small bowel ischemia‐reperfusion injury in rat

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Molecular cloning and functional analysis of serotonin N‐acetyltransferase from the cyanobacterium Synechocystis sp. PCC 6803

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The plastid ancestor originated among one of the major cyanobacterial lineages

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Horizontal transfer of mitochondria between mammalian cells: beyond co-culture approaches

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Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats

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Cell-to-cell movement of mitochondria in plants

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Cultured rat cortical astrocytes synthesize melatonin: absence of a diurnal rhythm

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Melatonin Signal Transduction Pathways Require E-Box-Mediated Transcription of Per1 and Per2 to Reset the SCN Clock at Dusk

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Protective effect of melatonin against the 1‐methyl‐4‐phenylpyridinium‐induced inhibition of Complex I of the mitochondrial respiratory chain

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Melatonin prevents adverse myocardial infarction remodeling via Notch1/Mfn2 pathway

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N -Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin

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Detection and quantification of melatonin in a dinoflagellate, Gonyaulax polyedra: Solutions to the problem of methoxyindole destruction in non‐vertebrate material

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Protective role of melatonin in mitochondrial dysfunction and related disorders

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The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of i NOS and preservation of n NOS

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Melatonin: A Potential Anti-Oxidant Therapeutic Agent for Mitochondrial Dysfunctions and Related Disorders

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Melatonin and Ischemic Stroke: Mechanistic Roles and Action

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CSF generation by pineal gland results in a robust melatonin circadian rhythm in the third ventricle as an unique light/dark signal

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Melatonin prevents cytosolic calcium overload, mitochondrial damage and cell death due to toxically high doses of dexamethasone-induced oxidative stress in human neuroblastoma SH-SY5Y cells

Suwanjang, W., Abramov, A. Y., Charngkaew, K., Govitrapong, P., & Chetsawang, B. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.05.003 · Cited by 77 · see citing works

Melatonin prevents the dynamin‐related protein 1‐dependent mitochondrial fission and oxidative insult in the cortical neurons after 1‐methyl‐4‐phenylpyridinium treatment

Chuang, J., Pan, I., Hsieh, C., Huang, C., Chen, P., & Shin, J.-W. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12343 · Cited by 76 · see citing works

Cyclic 3-Hydroxymelatonin: A Melatonin Metabolite Generated as a Result of Hydroxyl Radical Scavenging

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How to Achieve High-Quality Oocytes? The Key Role of Myo-Inositol and Melatonin

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Melatonin promotes adipogenesis and mitochondrial biogenesis in 3T3‐L1 preadipocytes

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Antioxidative protection in a high‐melatonin organism: The dinoflagellate Gonyaulax polyedra is rescued from lethal oxidative stress by strongly elevated, but physiologically possible concentrations of melatonin

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Cyclic 3-hydroxymelatonin, a key metabolite enhancing the peroxyl radical scavenging activity of melatonin

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Melatonin protects hepatocytes against bile acid-induced mitochondrial oxidative stress via the AMPK-SIRT3-SOD2 pathway

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Melatonin induces the expression of Nrf2-regulated antioxidant enzymes via PKC and Ca2+ influx activation in mouse pancreatic acinar cells

Santofimia‐Castaño, P., Ruy, D. C., Garcia-Sanchez, L., Jiménez-Blasco, D., Fernández‐Bermejo, M., Bolaños, J. P., Salido, G. M., & González, A. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.06.033 · Cited by 70 · see citing works

Melatonin restores the mitochondrial production of ATP in septic mice.

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Molecular Basis for Defining the Pineal Gland and Pinealocytes as Targets for Tumor Necrosis Factor

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Nix: A receptor protein for mitophagy in mammals

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Characterization of the Saccharomyces cerevisiae Homolog of the Melatonin Rhythm Enzyme Arylalkylamine N-Acetyltransferase (EC 2.3.1.87)

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Regulation by mitochondrial superoxide and NADPH oxidase of cellular formation of nitrated cyclic GMP: potential implications for ROS signalling

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Melatonin and structurally similar compounds have differing effects on inflammation and mitochondrial function in endothelial cells under conditions mimicking sepsis

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Daily differential expression of melatonin‐related genes and clock genes in rat cumulus–oocyte complex: changes after pinealectomy

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Liposomal melatonin rescues methamphetamine‐elicited mitochondrial burdens, pro‐apoptosis, and dopaminergic degeneration through the inhibition PKCδ gene

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Melatonin improves mitochondrial function in inguinal white adipose tissue of Zücker diabetic fatty rats

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Mitochondrial and Metabolic Dysfunction in Renal Convoluted Tubules of Obese Mice: Protective Role of Melatonin

Stacchiotti, A., Favero, G., Giugno, L., Lavazza, A., Reiter, R. J., Rodella, L. F., & Rezzani, R. (2014) · PLoS ONE · doi:10.1371/journal.pone.0111141 · Cited by 63 · see citing works

Melatonin improved rat cardiac mitochondria and survival rate in septic heart injury

Zhang, H., Liu, D., Wang, X., Chen, X., Long, Y., Chai, W., Zhou, X. Q., Xi, R., Zhang, Q., Wang, H., et al. (2012) · Journal of Pineal Research · doi:10.1111/jpi.12033 · Cited by 62 · see citing works

Melatonin treatment improves primary progressive multiple sclerosis: a case report

González, A. L., Álvarez‐Sánchez, N., Lardone, P. J., Cruz‐Chamorro, I., Martínez‐López, A., Guerrero, J. M., Reiter, R. J., & Carrillo‐Vico, A. (2014) · Journal of Pineal Research · doi:10.1111/jpi.12203 · Cited by 62 · see citing works

Mitochondrial Transfer from Astrocytes to Neurons following Ischemic Insult: Guilt by Association?

Berridge, M. V., Schneider, R. T., & McConnell, M. J. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.08.023 · Cited by 61 · see citing works

Decline in cytochrome c oxidase activity in rat-brain mitochondria with aging. Role of peroxidized cardiolipin and beneficial effect of melatonin

Petrosillo, G., Benedictis, V. D., Ruggiero, F. M., & Paradies, G. (2013) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-013-9505-0 · Cited by 60 · see citing works

Chloroplast-encoded serotonin N-acetyltransferase in the red alga Pyropia yezoensis: gene transition to the nucleus from chloroplasts

Byeon, Y., Lee, H. Y., Choi, D., & Back, K. (2014) · Journal of Experimental Botany · doi:10.1093/jxb/eru357 · Cited by 59 · see citing works

Melatonin reduces endoplasmic reticulum stress and autophagy in liver of leptin‐deficient mice

de Luxán‐Delgado, B., Potes, Y., Rubio‐González, A., Caballero, B., Solano, J. J., Fernández, M. F., Bermúdez, M., Guimarães, M. R. M., Vega‐Naredo, I., Boga, J. A., et al. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12333 · Cited by 59 · see citing works

Melatonin attenuates methamphetamine‐induced disturbances in mitochondrial dynamics and degeneration in neuroblastoma SH ‐ SY 5 Y cells

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Melatonin protects against chronic intermittent hypoxia-induced cardiac hypertrophy by modulating autophagy through the 5′ adenosine monophosphate-activated protein kinase pathway

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Exogenous melatonin enhances bile flow and ATP levels after cold storage and reperfusion in rat liver: implications for liver transplantation

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Mechanism of neuroprotection of melatonin against beta-amyloid neurotoxicity

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The effect of melatonin on antioxidant enzymes in human diabetic skin fibroblasts.

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Reactive Oxygen Species in the Cerebral Circulation: Are They All Bad?

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Effect and possible mechanisms of melatonin treatment on the quality and developmental potential of aged bovine oocytes

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Melatonin attenuates the mitochondrial translocation of mitochondrial fission proteins and Bax, cytosolic calcium overload and cell death in methamphetamine-induced toxicity in neuroblastoma SH-SY5Y cells

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Cardiac disease due to random mitochondrial DNA mutations is prevented by cyclosporin A

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Quantitation of ultrastructural changes in the mouse pineal in response to continuous illumination

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Melatonin protects lung mitochondria from aging

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Melatonin enhances thein vitromaturation and developmental potential of bovine oocytes denuded of the cumulus oophorus

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Dynamic comparisons of high-resolution expression profiles highlighting mitochondria-related genes between in vivo and in vitro fertilized early mouse embryos

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Melatonin modulates permeability transition pore and 5-hydroxydecanoate induced KATP channel inhibition in isolated brain mitochondria

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Ultrastructure of the pineal gland in the adult rat.

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Melatonin reduces early changes in intramitochondrial cardiolipin during apoptosis in U937 cell line

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Mitochondria, calcium, and tumor suppressor Fus1: At the crossroad of cancer, inflammation, and autoimmunity

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Exercise-induced oxidative stress and melatonin supplementation: current evidence

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Evidence for the Benefits of Melatonin in Cardiovascular Disease

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Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3

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Melatonin: the placental antioxidant and anti-inflammatory

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Gut Dysbiosis Dysregulates Central and Systemic Homeostasis via Suboptimal Mitochondrial Function: Assessment, Treatment and Classification Implications

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The Interplay Between Adipose Tissue and Vasculature: Role of Oxidative Stress in Obesity

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Mitochondrial Dysfunction: A Key Player in Brain Aging and Diseases

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Role of Mitochondria in Retinal Pigment Epithelial Aging and Degeneration

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Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy

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Melatonin Supplementation Lowers Oxidative Stress and Regulates Adipokines in Obese Patients on a Calorie‐Restricted Diet

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Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high‐fat diet

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Melatonin improves the effect of cryopreservation on human oocytes by suppressing oxidative stress and maintaining the permeability of the oolemma

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Melatonin and cancer: From the promotion of genomic stability to use in cancer treatment

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Nutrients to Improve Mitochondrial Function to Reduce Brain Energy Deficit and Oxidative Stress in Migraine

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Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS-Induced Cardiomyopathy

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SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatonin

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Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment

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Structural and physico-chemical evaluation of melatonin and its solution-state excited properties, with emphasis on its binding with novel coronavirus proteins

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Boosting immune system against cancer by melatonin: A mechanistic viewpoint

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Melatonin Improves the Quality of Inferior Bovine Oocytes and Promoted Their Subsequent IVF Embryo Development: Mechanisms and Results

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The Endoplasmic Reticulum Stress Response in Neuroprogressive Diseases: Emerging Pathophysiological Role and Translational Implications

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The role and therapeutic potential of melatonin in age‐related ocular diseases

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Melatonin Supplementation Decreases Hypertrophic Obesity and Inflammation Induced by High-Fat Diet in Mice

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The potential role of melatonin in retarding intervertebral disc ageing and degeneration: A systematic review

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Mechanisms Underlying Tumor Suppressive Properties of Melatonin

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Tryptophan Metabolism: A Versatile Area Providing Multiple Targets for Pharmacological Intervention

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The Vital Role of Melatonin and Its Metabolites in the Neuroprotection and Retardation of Brain Aging

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Melatonin protects against behavioral deficits, dopamine loss and oxidative stress in homocysteine model of Parkinson's disease

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Effects of inflammation and oxidative stress on postoperative delirium in cardiac surgery

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Melatonin increases human cervical cancer HeLa cells apoptosis induced by cisplatin via inhibition of JNK/Parkin/mitophagy axis

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Ameliorating mitochondrial dysfunction restores carbon ion-induced cognitive deficits via co-activation of NRF2 and PINK1 signaling pathway

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Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases

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Melatonin: A mitochondrial resident with a diverse skill set

Reiter, R. J., Sharma, R., Rosales‐Corral, S., Zuccari, D. A. P. D. C., & Chuffa, L. G. D. A. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120612 · Cited by 68 · see citing works

Cadmium induced bioaccumulation, histopathology, gene regulation in fish and its amelioration – A review

Das, S., Kar, I., & Patra, A. K. (2023) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2023.127202 · Cited by 69 · see citing works

Melatonin, mitochondria, and the metabolic syndrome

Cardinali, D. P., & Vigo, D. E. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2611-0 · Cited by 70 · see citing works

Protective effects of melatonin on male fertility preservation and reproductive system

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Melatonin enhances SIRT1 to ameliorate mitochondrial membrane damage by activating PDK1/Akt in granulosa cells of PCOS

Zheng, B., Meng, J., Zhu, Y., Ding, M., Zhang, Y., & Zhou, J. (2021) · Journal of Ovarian Research · doi:10.1186/s13048-021-00912-y · Cited by 64 · see citing works

Mitochondrial bioenergetics decay in aging: beneficial effect of melatonin

Paradies, G., Paradies, V., Ruggiero, F. M., & Petrosillo, G. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2619-5 · Cited by 64 · see citing works

Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective

Sevilla, A., Chéret, J., Slominski, R. M., Slominski, A. T., & Paus, R. (2022) · Journal of Pineal Research · doi:10.1111/jpi.12790 · Cited by 63 · see citing works

Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development

Silva, B. R., & Silva, J. R. V. (2022) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2022.107186 · Cited by 61 · see citing works

Design and validation of the first cell‐impermeant melatonin receptor agonist

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Targeting Host Defense System and Rescuing Compromised Mitochondria to Increase Tolerance against Pathogens by Melatonin May Impact Outcome of Deadly Virus Infection Pertinent to COVID-19

Tan, D. X., & Hardeland, R. (2020) · Molecules · doi:10.3390/molecules25194410 · Cited by 60 · see citing works

Melatonin and Cancer: A Polyhedral Network Where the Source Matters

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Alpha-synuclein, epigenetics, mitochondria, metabolism, calcium traffic, & circadian dysfunction in Parkinson’s disease. An integrated strategy for management

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Mini-encyclopedia of mitochondria-relevant nutraceuticals protecting health in primary and secondary care—clinically relevant 3PM innovation

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Clinical Trials for Use of Melatonin to Fight against COVID-19 Are Urgently Needed

Kleszczyński, K., Slominski, A. T., Steinbrink, K., & Reiter, R. J. (2020) · Nutrients · doi:10.3390/nu12092561 · Cited by 58 · see citing works

Melatonin rescues cerebral ischemic events through upregulated tunneling nanotube-mediated mitochondrial transfer and downregulated mitochondrial oxidative stress in rat brain

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Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N6-Methyladenosine Modification

Lv, Y., Li, T., Yang, M., Su, L., Zhu, Z., Zhao, S., Zeng, W., & Zheng, Y. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.684398 · Cited by 58 · see citing works

Melatonin, mitochondria, and the cancer cell

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Diabetes mellitus and melatonin: Where are we?

Patel, R., PARMAR, N. R., Palit, S. P., RATHWA, N. N., Ramachandran, A. V., & Begum, R. (2022) · Biochimie · doi:10.1016/j.biochi.2022.01.001 · Cited by 58 · see citing works

Aging-Related Ovarian Failure and Infertility: Melatonin to the Rescue

Reiter, R., Sharma, R., Romero, A., Manucha, W., Tan, D., Zuccari, D. A. P. D. C., & Chuffa, L. G. D. A. (2023) · Antioxidants · doi:10.3390/antiox12030695 · Cited by 64 · see citing works

Melatonin inhibits the apoptosis of rooster Leydig cells by suppressing oxidative stress via AKT-Nrf2 pathway activation

Dong, Y., Zhao, J., Zhu, Q., Liu, H., Wang, J., & Lu, W. (2020) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2020.06.024 · Cited by 56 · see citing works

Mitochondria Need Their Sleep: Redox, Bioenergetics, and Temperature Regulation of Circadian Rhythms and the Role of Cysteine-Mediated Redox Signaling, Uncoupling Proteins, and Substrate Cycles

Richardson, R. B., & Mailloux, R. J. (2023) · Antioxidants · doi:10.3390/antiox12030674 · Cited by 56 · see citing works

Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic‐ischaemic brain injury

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Function, Mechanism, and Application of Plant Melatonin: An Update with a Focus on the Cereal Crop, Barley (Hordeum vulgare L.)

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Direct comparison of Arabidopsis gene expression reveals different responses to melatonin versus auxin

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Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm

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Neuroprotective Effects of Melatonin during Demyelination and Remyelination Stages in a Mouse Model of Multiple Sclerosis

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The role of melatonin in targeting cell signaling pathways in neurodegeneration

Shukla, M., Chinchalongporn, V., Govitrapong, P., & Reiter, R. J. (2019) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14005 · Cited by 51 · see citing works

Neuro-Inflammation Modulation and Post-Traumatic Brain Injury Lesions: From Bench to Bed-Side

Jacquens, A., Needham, E., Zanier, E. R., Degos, V., Gressèns, P., & Menon, D. K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911193 · Cited by 51 · see citing works

Melatonin: A mitochondrial resident with a diverse skill set

Reiter, R. J., Sharma, R., Rosales‐Corral, S., Zuccari, D. A. P. D. C., & Chuffa, L. G. D. A. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120612 · Cited by 68 · see citing works

Mitochondria: the birth place, battle ground and the site of melatonin metabolism in cells

Tan, D.-X., & Reiter, R. J. (2019) · Melatonin Research · doi:10.32794/mr11250011 · Cited by 172 · see citing works

Melatonin Targets Mitochondrial Redox Homeostasis: Optimizing the Intracellular Microenvironment

Reiter, R. J., Sharma, R., Loh, D., Chuffa, L. G. D. A., Bai, Y., Zuccari, D. A. P. D. C., Galano, A., & Manucha, W. A. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27104496 · Cited by 2 · see citing works

Melatonin role in the mitochondrial function

Acuña-Castroviejo, D. (2006) · Frontiers in bioscience · doi:10.2741/2116 · Cited by 155 · see citing works

The potential influence of melatonin on mitochondrial quality control: a review

Lei, X., Xu, Z., Huang, L., Huang, Y., Tu, S., Xu, L., & Liu, D. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1332567 · Cited by 36 · see citing works