Cited by 126Gut microbiota and healthNuts composition and effectsNutritional Studies and Diet

Almond Consumption and Processing Affects the Composition of the Gastrointestinal Microbiota of Healthy Adult Men and Women: A Randomized Controlled Trial

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Holscher, Hannah, Taylor, Andrew, Swanson, Kelly, Novotny, Janet, Baer, David·2018·Nutrients

Abstract

Background: Almond processing has been shown to differentially impact metabolizable energy; however, the effect of food form on the gastrointestinal microbiota is under-investigated. Objective: We aimed to assess the interrelationship of almond consumption and processing on the gastrointestinal microbiota. Design: A controlled-feeding, randomized, five-period, crossover study with washouts between diet periods was conducted in healthy adults (n = 18). Treatments included: (1) zero servings/day of almonds (control); (2) 1.5 servings (42 g)/day of whole almonds; (3) 1.5 servings/day of whole, roasted almonds; (4) 1.5 servings/day of roasted, chopped almonds; and (5) 1.5 servings/day of almond butter. Fecal samples were collected at the end of each three-week diet period. Results: Almond consumption increased the relative abundances of Lachnospira, Roseburia, and Dialister (p ≤ 0.05). Comparisons between control and the four almond treatments revealed that chopped almonds increased Lachnospira, Roseburia, and Oscillospira compared to control (p < 0.05), while whole almonds increased Dialister compared to control (p = 0.007). There were no differences between almond butter and control. Conclusions: These results reveal that almond consumption induced changes in the microbial community composition of the human gastrointestinal microbiota. Furthermore, the degree of almond processing (e.g., roasting, chopping, and grinding into butter) differentially impacted the relative abundances of bacterial genera.

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  • A significant impact on the gut microbiota has previously been displayed through the consumption of cruciferous vegetables, walnuts, and almonds (consumption and processing) amongst others.

    “A significant impact on the gut microbiota has previously been displayed through the consumption of cruciferous vegetables, walnuts, and almonds (consumption and processing) amongst others [113,114,115].”

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Authors
Holscher, H., Taylor, A., Swanson, K., Novotny, J., & Baer, D.
Affiliations
  • University of Illinois Urbana-Champaign (US)
  • Beltsville Human Nutrition Research Center (US)
Corresponding author
Holscher, Hannah
Venue
Nutrients
Publisher
MDPI AG
Published
2018-01-26
Volume
10
Issue
2
Pages
126
ISSN
2072-6643 (ISSN-L)
OpenAlex
W2788531829
Cited by
126
References
42
Citations by year
2026: 7 · 2025: 16 · 2024: 15 · 2023: 15 · 2022: 18 · 2021: 17 · 2020: 19 · 2019: 12 · 2018: 7
FWCI
4.89
Type
journal article
Language
en
Open access
Locations
  • Nutrients (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • U.S. Department of Agriculture
  • Almond Board of California
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Nursing › Nutrition and Dietetics › Nuts composition and effects
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords
almond consumption, almond processing, gut microbiota, gut microbiota composition, Lachnospira, Roseburia, Dialister, Oscillospira, food form, healthy adults
MeSH terms
Clostridiales, Eubacteriales, Prunus dulcis, Gastrointestinal Microbiome, Aged, Condiments, Cooking, Feces, Female, Follow-Up Studies, Food Handling, Humans, Male, Middle Aged, Nuts, Cross-Over Studies, Veillonellaceae, Functional Food, Molecular Typing, Dysbiosis

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