Most cited biochemistry, genetics and molecular biology papers
- Verified
Web-based survival analysis tool tailored for medical research (KMplot): Development and implementation
Lánczky, A., & Győrffy, B. (2021) · Journal of Medical Internet Research
Bioinformatics and Genomic NetworksGene expression and cancer classification
Cited by 1,694
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scGPT: Towards Building a Foundation Model for Single-Cell Multi-omics Using Generative AI
Cui, H., Wang, C., Maan, H., Pang, K., Luo, F., & Wang, B. (2023) · Nature Methods
Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks
Cited by 1,694
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Species-level functional profiling of metagenomes and metatranscriptomes
Franzosa, E. A., McIver, L. J., Rahnavard, G., Thompson, L. R., Schirmer, M., Weingart, G., Lipson, K. S., Knight, R., Caporaso, J. G., Segata, N., et al. (2018) · Nature Methods
Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology
Cited by 1,693
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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
Keith, B., Johnson, R. S., & Simon, M. C. (2012) · Nature Reviews Cancer
Cancer, Hypoxia, and MetabolismKruppel-like factors research
Cited by 1,693
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NF-κB, the first quarter-century: remarkable progress and outstanding questions
Hayden, M. S., & Ghosh, S. (2012) · Genes & Development
NF-κB Signaling PathwaysSignaling Pathways in Disease
Cited by 1,693
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VEGF-Trap: A VEGF blocker with potent antitumor effects
Holash, J., Davis, S., Papadopoulos, N., Croll, S. D., Ho, L., Russell, M., Boland, P., Leidich, R., Hylton, D., Burova, E., et al. (2002) · Proceedings of the National Academy of Sciences
Angiogenesis and VEGF in CancerMonoclonal and Polyclonal Antibodies Research
Cited by 1,691
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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
Han, J., Back, S. H., Hur, J., Lin, Y.-H., Gildersleeve, R., Shan, J., Yuan, C. L., Krokowski, D., Wang, S., Hatzoglou, M., et al. (2013) · Nature Cell Biology
Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research
Cited by 1,691
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Pseudomonas aeruginosa Displays Multiple Phenotypes during Development as a Biofilm
Sauer, K., Camper, A. K., Ehrlich, G. D., Costerton, J. W., & Davies, D. G. (2002) · Journal of Bacteriology
Bacterial biofilms and quorum sensingBacterial Genetics and Biotechnology
Cited by 1,691
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Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
Joe, A. W. B., Yi, L., Natarajan, A., Le Grand, F., So, L., Wang, J., Rudnicki, M. A., & Rossi, F. M. V. (2010) · Nature Cell Biology
Muscle Physiology and DisordersMesenchymal stem cell research
Cited by 1,690
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Radical causes of cancer
Hussain, S. P., Hofseth, L. J., & Harris, C. C. (2003) · Nature Reviews Cancer
Redox biology and oxidative stressCancer and biochemical research
Cited by 1,690
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The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment
Zhang, X., Zhang, D., Jia, H., Feng, Q., Wang, D., Liang, D., Wu, X., Li, J., Tang, L., Li, Y., et al. (2015) · Nature Medicine
Gut microbiota and healthRheumatoid Arthritis Research and Therapies
Cited by 1,690
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Openings Between Defective Endothelial Cells Explain Tumor Vessel Leakiness
Hashizume, H., Baluk, P., Morikawa, S., McLean, J. W., Thurston, G., Roberge, S., Jain, R. K., & McDonald, D. M. (2000) · The American Journal of Pathology
Angiogenesis and VEGF in CancerBarrier Structure and Function Studies
Cited by 1,689
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The microbiome and cancer
Schwabe, R. F., & Jobin, C. (2013) · Nature Reviews Cancer
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,689
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The Controversial Role of Human Gut Lachnospiraceae
Vacca, M., Celano, G., Calabrese, F. M., Portincasa, P., Gobbetti, M., & De Angelis, M. (2020) · Microorganisms
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 1,688
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A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
Clark, J. D., Lin, L.-L., Kriz, R. W., Ramesha, C. S., Sultzman, L. A., Lin, A. Y., Milona, N., & Knopf, J. L. (1991) · Cell
Protein Kinase Regulation and GTPase SignalingLipid metabolism and biosynthesis
Cited by 1,688
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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
Brooks-Wilson, A., Marcil, M., Clee, S. M., Zhang, L.-H., Roomp, K., van Dam, M., Yu, L., Brewer, C., Collins, J. A., Molhuizen, H. O. F., et al. (1999) · Nature Genetics
Cholesterol and Lipid MetabolismLipid metabolism and disorders
Cited by 1,687
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Emergent Properties of Networks of Biological Signaling Pathways
Bhalla, U. S., & Iyengar, R. (1999) · Science
Gene Regulatory Network AnalysisBioinformatics and Genomic Networks
Cited by 1,686
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ScanProsite: detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteins
de Castro, E., Sigrist, C. J. A., Gattiker, A., Bulliard, V., Langendijk-Genevaux, P. S., Gasteiger, E., Bairoch, A., & Hulo, N. (2006) · Nucleic Acids Research
Genomics and Phylogenetic StudiesMachine Learning in Bioinformatics
Cited by 1,686
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Gut microbiota dysbiosis contributes to the development of hypertension
Li, J., Zhao, F., Wang, Y., Chen, J., Tao, J., Tian, G., Wu, S., Liu, W., Cui, Q., Geng, B., et al. (2017) · Microbiome
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,685
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Analysis of apoptosis by propidium iodide staining and flow cytometry
Riccardi, C., & Nicoletti, I. (2006) · Nature Protocols
Cell death mechanisms and regulationCell Image Analysis Techniques
Cited by 1,685
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Genotype-environment interaction and correlation in the analysis of human behavior.
Plomin, R., DeFries, J. C., & Loehlin, J. C. (1977) · Psychological Bulletin
Genetic Associations and EpidemiologyCognitive Abilities and Testing
Cited by 1,685
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A CRISPR/Cas9 toolkit for multiplex genome editing in plants
Xing, H.-L., Dong, L., Wang, Z.-P., Zhang, H.-Y., Han, C.-Y., Liu, B., Wang, X.-C., & Chen, Q.-J. (2014) · BMC Plant Biology
CRISPR and Genetic EngineeringPlant Genetic and Mutation Studies
Cited by 1,684
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Quantitative reactivity profiling predicts functional cysteines in proteomes
Weerapana, E., Wang, C., Simon, G. M., Richter, F., Khare, S., Dillon, M. B. D., Bachovchin, D. A., Mowen, K., Baker, D., & Cravatt, B. F. (2010) · Nature
Redox biology and oxidative stressAdvanced Proteomics Techniques and Applications
Cited by 1,684
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Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).
Griffith, O. W., & Meister, A. (1979) · Journal of Biological Chemistry
Sulfur Compounds in BiologyGlutathione Transferases and Polymorphisms
Cited by 1,683
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