Most cited biochemistry, genetics and molecular biology papers
- Verified
Genetic and pharmacological disruption of the TEAD–YAP complex suppresses the oncogenic activity of YAP
Liu-Chittenden, Y., Huang, B., Shim, J. S., Chen, Q., Lee, S.-J., Anders, R. A., Liu, J. O., & Pan, D. (2012) · Genes & Development
Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research
Cited by 1,452
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Prader-Willi syndrome
Cassidy, S. B., Schwartz, S., Miller, J. L., & Driscoll, D. J. (2012) · Genetics in Medicine
Genetic Syndromes and ImprintingGenomic variations and chromosomal abnormalities
Cited by 1,452
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Mechanisms of specificity in protein phosphorylation
Ubersax, J. A., & Ferrell Jr, J. E. (2007) · Nature Reviews Molecular Cell Biology
Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases
Cited by 1,451
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Insights into Molecular Classifications of Triple-Negative Breast Cancer: Improving Patient Selection for Treatment
Garrido-Castro, A. C., Lin, N. U., & Polyak, K. (2019) · Cancer Discovery
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 1,451
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S100A8/A9 in Inflammation
Wang, S., Song, R., Wang, Z., Jing, Z., Wang, S., & Ma, J. (2018) · Frontiers in Immunology
S100 Proteins and AnnexinsBiomarkers in Disease Mechanisms
Cited by 1,450
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Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis
Thaiss, C. A., Zeevi, D., Levy, M., Zilberman-Schapira, G., Suez, J., Tengeler, A. C., Abramson, L., Katz, M. N., Korem, T., Zmora, N., et al. (2014) · Cell
Gut microbiota and healthCircadian rhythm and melatonin
Cited by 1,449
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Asymmetric self-renewal and commitment of satellite stem cells in muscle
Kuang, S., Kuroda, K., Le Grand, F., & Rudnicki, M. A. (2007) · Cell
Muscle Physiology and DisordersDevelopmental Biology and Gene Regulation
Cited by 1,449
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Widespread parallel evolution in sticklebacks by repeated fixation of Ectodysplasin alleles.
Colosimo, P. F., Hosemann, K. E., Balabhadra, S., Villarreal, G., Dickson, M., Grimwood, J., Schmutz, J., Myers, R. M., Schluter, D., & Kingsley, D. M. (2005) · Science
Evolution and Genetic DynamicsDevelopmental Biology and Gene Regulation
Cited by 1,448
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CellChat for systematic analysis of cell–cell communication from single-cell transcriptomics
Jin, S., Plikus, M. V., & Nie, Q. (2025) · Nature Protocols
Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks
Cited by 1,448
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Molecular physiology of reverse cholesterol transport.
Fielding, C. J., & Fielding, P. E. (1995) · Journal of Lipid Research
Cholesterol and Lipid MetabolismDrug Transport and Resistance Mechanisms
Cited by 1,448
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Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions
Klengel, T., Mehta, D., Anacker, C., Rex-Haffner, M., Pruessner, J. C., Pariante, C. M., Pace, T. W. W., Mercer, K. B., Mayberg, H. S., Bradley, B., et al. (2013) · Nature Neuroscience
Epigenetics and DNA MethylationStress Responses and Cortisol
Cited by 1,447
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Chemically defined conditions for human iPSC derivation and culture
Chen, G., Gulbranson, D. R., Hou, Z., Bolin, J. M., Ruotti, V., Probasco, M. D., Smuga-Otto, K., Howden, S. E., Diol, N. R., Propson, N. E., et al. (2011) · Nature Methods
Pluripotent Stem Cells ResearchMesenchymal stem cell research
Cited by 1,447
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TGFβ2 knockout mice have multiple developmental defects that are non-overlapping with other TGFβ knockout phenotypes
Sanford, L. P., Ormsby, I., Groot, A. C. G.-D., Sariola, H., Friedman, R., Boivin, G. P., Cardell, E. L., & Doetschman, T. (1997) · Development
Developmental Biology and Gene RegulationTGF-β signaling in diseases
Cited by 1,447
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Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
Dolma, S., Lessnick, S. L., Hahn, W. C., & Stockwell, B. R. (2003) · Cancer Cell
Cancer therapeutics and mechanismsCancer-related Molecular Pathways
Cited by 1,446
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De Novo Gene Disruptions in Children on the Autistic Spectrum
Iossifov, I., Ronemus, M., Levy, D., Wang, Z., Hakker, I., Rosenbaum, J., Yamrom, B., Lee, Y.-H., Narzisi, G., Leotta, A., et al. (2012) · Neuron
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 1,446
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Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy
Delettre, C., Lenaers, G., Griffoin, J.-M., Gigarel, N., Lorenzo, C., Belenguer, P., Pelloquin, L., Grosgeorge, J., Turc-Carel, C., Perret, E., et al. (2000) · Nature Genetics
Mitochondrial Function and PathologyHereditary Neurological Disorders
Cited by 1,446
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The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter
Dynan, W. S., & Tjian, R. (1983) · Cell
Genomics and Chromatin DynamicsPolyomavirus and related diseases
Cited by 1,445
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Mesenchymal Stem Cell Homing: The Devil Is in the Details
Karp, J. M., & Leng Teo, G. S. (2009) · Cell Stem Cell
Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation
Cited by 1,445
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Metformin improves healthspan and lifespan in mice
Martin-Montalvo, A., Mercken, E. M., Mitchell, S. J., Palacios, H. H., Mote, P. L., Scheibye-Knudsen, M., Gomes, A. P., Ward, T. M., Minor, R. K., Blouin, M.-J., et al. (2013) · Nature Communications
Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer
Cited by 1,445
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An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles
Clemson, C. M., Hutchinson, J. N., Sara, S. A., Ensminger, A. W., Fox, A. H., Chess, A., & Lawrence, J. B. (2009) · Molecular Cell
RNA Research and SplicingCancer-related molecular mechanisms research
Cited by 1,445
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Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
Pétrilli, V, Papin, S., Dostert, C., Mayor, A., Martinon, F., & Tschopp, J. (2007) · Cell Death & Differentiation
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 1,445
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Stem Cell Function, Self-Renewal, and Behavioral Heterogeneity of Cells from the Adult Muscle Satellite Cell Niche
Collins, C. A., Olsen, I., Zammit, P. S., Heslop, L., Petrie, A., Partridge, T. A., & Morgan, J. E. (2005) · Cell
Muscle Physiology and DisordersCongenital heart defects research
Cited by 1,445
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Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.
Whitesell, L., Mimnaugh, E. G., De Costa, B., Myers, C. E., & Neckers, L. M. (1994) · Proceedings of the National Academy of Sciences
Heat shock proteins researchProtein Kinase Regulation and GTPase Signaling
Cited by 1,444
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ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis
Ishikawa, K., Takenaga, K., Akimoto, M., Koshikawa, N., Yamaguchi, A., Imanishi, H., Nakada, K., Honma, Y., & Hayashi, J.-I. (2008) · Science
Mitochondrial Function and PathologyCancer, Hypoxia, and Metabolism
Cited by 1,444
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