Most cited biochemistry, genetics and molecular biology papers
- Verified
Resolving Individuals Contributing Trace Amounts of DNA to Highly Complex Mixtures Using High-Density SNP Genotyping Microarrays
Homer, N., Szelinger, S., Redman, M., Duggan, D., Tembe, W., Muehling, J., Pearson, J. V., Stephan, D. A., Nelson, S. F., & Craig, D. W. (2008) · PLoS Genetics
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 1,221
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Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.
Edwards, D. R., Murphy, G., Reynolds, J. J., Whitham, S. E., Docherty, A. J., Angel, P., & Heath, J. K. (1987) · The EMBO Journal
TGF-β signaling in diseasesProtease and Inhibitor Mechanisms
Cited by 1,221
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The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism
Murphy, J. M., Czabotar, P. E., Hildebrand, J. M., Lucet, I. S., Zhang, J.-G., Alvarez-Diaz, S., Lewis, R., Lalaoui, N., Metcalf, D., Webb, A. I., et al. (2013) · Immunity
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 1,220
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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
Hickson, I., Zhao, Y., Richardson, C. J., Green, S. J., Martin, N. M. B., Orr, A. I., Reaper, P. M., Jackson, S. P., Curtin, N. J., & Smith, G. C. M. (2004) · Cancer Research
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 1,220
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Oncogene-induced senescence as an initial barrier in lymphoma development
Braig, M., Lee, S., Loddenkemper, C., Rudolph, C., Peters, A. H. F. M., Schlegelberger, B., Stein, H., Dörken, B., Jenuwein, T., & Schmitt, C. A. (2005) · Nature
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 1,220
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The Sulfur-Containing Amino Acids: An Overview
Brosnan, J. T., & Brosnan, M. E. (2006) · The Journal of Nutrition
Sulfur Compounds in BiologyFolate and B Vitamins Research
Cited by 1,220
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The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
Hemann, M. T., Strong, M. A., Hao, L.-Y., & Greider, C. W. (2001) · Cell
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,219
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PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene–disease associations
Denny, J. C., Ritchie, M. D., Basford, M. A., Pulley, J. M., Bastarache, L., Brown-Gentry, K., Wang, D., Masys, D. R., Roden, D. M., & Crawford, D. C. (2010) · Bioinformatics
Genetic Associations and EpidemiologyHealth, Environment, Cognitive Aging
Cited by 1,219
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Mitogen-Activated Protein Kinases and Reactive Oxygen Species: How Can ROS Activate MAPK Pathways?
Son, Y., Cheong, Y.-K., Kim, N.-H., Chung, H.-T., Kang, D. G., & Pae, H.-O. (2011) · Journal of Signal Transduction
Redox biology and oxidative stressProtein Tyrosine Phosphatases
Cited by 1,219
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Control of telomere length by the human telomeric protein TRF1
van Steensel, B., & de Lange, T. (1997) · Nature
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,219
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Chromosomal stability and the DNA double-stranded break connection
van Gent, D. C., Hoeijmakers, J. H. J., & Kanaar, R. (2001) · Nature Reviews Genetics
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 1,219
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Persistent oxidative stress in cancer
Toyokuni, S., Okamoto, K., Yodoi, J., & Hiai, H. (1995) · FEBS Letters
Redox biology and oxidative stressCancer and biochemical research
Cited by 1,219
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Obesity-associated variants within FTO form long-range functional connections with IRX3
Smemo, S., Tena, J. J., Kim, K.-H., Gamazon, E. R., Sakabe, N. J., Gómez-Marín, C., Aneas, I., Credidio, F. L., Sobreira, D. R., Wasserman, N. F., et al. (2014) · Nature
Genomics and Chromatin DynamicsGenetic Associations and Epidemiology
Cited by 1,219
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DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins
Woo, J. W., Kim, J., Kwon, S. I., Corvalán, C., Cho, S. W., Kim, H., Kim, S.-G., Kim, S.-T., Choe, S., & Kim, J.-S. (2015) · Nature Biotechnology
CRISPR and Genetic EngineeringTransgenic Plants and Applications
Cited by 1,219
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Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth
Zanconato, F., Forcato, M., Battilana, G., Azzolin, L., Quaranta, E., Bodega, B., Rosato, A., Bicciato, S., Cordenonsi, M., & Piccolo, S. (2015) · Nature Cell Biology
Hippo pathway signaling and YAP/TAZGenomics and Chromatin Dynamics
Cited by 1,219
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Quantitative microbiome profiling links gut community variation to microbial load
Vandeputte, D., Kathagen, G., D’hoe, K., Vieira-Silva, S., Valles-Colomer, M., Sabino, J., Wang, J., Tito, R. Y., De Commer, L., Darzi, Y., et al. (2017) · Nature
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 1,218
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Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration
Schmued, L. C., & Hopkins, K. J. (2000) · Brain Research
Advanced Fluorescence Microscopy TechniquesNeuroscience and Neuropharmacology Research
Cited by 1,218
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DNA transposons and the evolution of eukaryotic genomes.
Feschotte, C., & Pritham, E. J. (2007) · Annual Review of Genetics
Chromosomal and Genetic VariationsGenome Rearrangement Algorithms
Cited by 1,218
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IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis
Varfolomeev, E., Blankenship, J. W., Wayson, S. M., Fedorova, A. V., Kayagaki, N., Garg, P., Zobel, K., Dynek, J. N., Elliott, L. O., Wallweber, H. J. A., et al. (2007) · Cell
Cell death mechanisms and regulationNF-κB Signaling Pathways
Cited by 1,218
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The sites and topology of mitochondrial superoxide production
Brand, M. D. (2010) · Experimental Gerontology
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 1,217
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Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases
Taguchi, A., Blood, D. C., del Toro, G., Canet, A., Lee, D. C., Qu, W., Tanji, N., Lu, Y., Lalla, E., Fu, C., et al. (2000) · Nature
Advanced Glycation End Products researchGalectins and Cancer Biology
Cited by 1,217
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Hedgehog: functions and mechanisms
Varjosalo, M., & Taipale, J. (2008) · Genes & Development
Hedgehog Signaling Pathway StudiesHippo pathway signaling and YAP/TAZ
Cited by 1,217
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Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
Petrif, F., Giles, R. H., Dauwerse, H. G., Saris, J. J., Hennekam, R. C. M., Masuno, M., Tommerup, N., van Ommen, G.-J. B., Goodman, R. H., Peters, D. J. M., et al. (1995) · Nature
Congenital limb and hand anomaliesGenomics and Rare Diseases
Cited by 1,217
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Vertebrate MicroRNA Genes
Lim, L. P., Glasner, M. E., Yekta, S., Burge, C. B., & Bartel, D. P. (2003) · Science
MicroRNA in disease regulationGenomics and Phylogenetic Studies
Cited by 1,217
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