Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Nuclear Receptors, RXR, and the Big Bang

Evans, R. M., & Mangelsdorf, D. J. (2014) · Cell

Nuclear Receptors and SignalingRetinoids in leukemia and cellular processes

Cited by 1,200

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

Wardyn, J. D., Ponsford, A. H., & Sanderson, C. M. (2015) · Biochemical Society Transactions

Genomics, phytochemicals, and oxidative stressNF-κB Signaling Pathways

Cited by 1,200

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

Lamming, D. W., Ye, L., Katajisto, P., Goncalves, M. D., Saitoh, M., Stevens, D. M., Davis, J. G., Salmon, A. B., Richardson, A., Ahima, R. S., et al. (2012) · Science

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 1,199

Lysosome-targeting chimaeras for degradation of extracellular proteins

Banik, S. M., Pedram, K., Wisnovsky, S., Ahn, G., Riley, N. M., & Bertozzi, C. R. (2020) · Nature

Protein Degradation and InhibitorsRNA Interference and Gene Delivery

Cited by 1,199

A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

Singh, N. A., Charlier, C., Stauffer, D., DuPont, B. R., Leach, R. J., Melis, R., Ronen, G. M., Bjerre, I., Quattlebaum, T., Murphy, J. V., et al. (1998) · Nature Genetics

Ion channel regulation and functionEpilepsy research and treatment

Cited by 1,199

A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action

Makarova, K. S., Grishin, N. V., Shabalina, S. A., Wolf, Y. I., & Koonin, E. V. (2006) · Biology Direct

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 1,199

Gene Body Methylation Can Alter Gene Expression and Is a Therapeutic Target in Cancer

Yang, X., Han, H., De Carvalho, D. D., Lay, F. D., Jones, P. A., & Liang, G. (2014) · Cancer Cell

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,199

A constant rate of spontaneous mutation in DNA-based microbes.

Drake, J. W. (1991) · Proceedings of the National Academy of Sciences

Evolution and Genetic DynamicsRNA and protein synthesis mechanisms

Cited by 1,199

Crystal Structure of a Ternary FGF-FGFR-Heparin Complex Reveals a Dual Role for Heparin in FGFR Binding and Dimerization

Schlessinger, J., Plotnikov, A. N., Ibrahimi, O. A., Eliseenkova, A. V., Yeh, B. K., Yayon, A., Linhardt, R. J., & Mohammadi, M. (2000) · Molecular Cell

Fibroblast Growth Factor ResearchEnzyme Structure and Function

Cited by 1,199

Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway

Garcia-Higuera, I., Taniguchi, T., Ganesan, S., Meyn, M. S., Timmers, C., Hejna, J., Grompe, M., & D'Andrea, A. D. (2001) · Molecular Cell

DNA Repair MechanismsBlood disorders and treatments

Cited by 1,198

Use of Unlinked Genetic Markers to Detect Population Stratification in Association Studies

Pritchard, J. K., & Rosenberg, N. A. (1999) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 1,198

RNA-Seq gene expression estimation with read mapping uncertainty

Li, B., Ruotti, V., Stewart, R. M., Thomson, J. A., & Dewey, C. N. (2010) · Bioinformatics

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 1,198

A reference map of the human binary protein interactome

Luck, K., Kim, D.-K., Lambourne, L., Spirohn, K., Begg, B. E., Bian, W., Brignall, R., Cafarelli, T., Campos-Laborie, F. J., Charloteaux, B., et al. (2020) · Nature

Bioinformatics and Genomic NetworksAdvanced Proteomics Techniques and Applications

Cited by 1,197

Discovering regulatory and signalling circuits in molecular interaction networks

Ideker, T., Ozier, O., Schwikowski, B., & Siegel, A. F. (2002) · Bioinformatics

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 1,197

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

Südhof, T. C. (2013) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 1,197

Nicotinic Acetylcholine Receptors and Nicotinic Cholinergic Mechanisms of the Central Nervous System

Dani, J. A., & Bertrand, D. (2007) · Annual Review of Pharmacology and Toxicology

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 1,197

Are Rare Variants Responsible for Susceptibility to Complex Diseases?

Pritchard, J. K. (2001) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyEvolution and Genetic Dynamics

Cited by 1,197

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Zhong, Z., Umemura, A., Sanchez-Lopez, E., Liang, S., Shalapour, S., Wong, J., He, F., Boassa, D., Perkins, G., Ali, S. R., et al. (2016) · Cell

Inflammasome and immune disordersNF-κB Signaling Pathways

Cited by 1,197

The vacuolar (H+)-ATPases — nature's most versatile proton pumps

Nishi, T., & Forgac, M. (2002) · Nature Reviews Molecular Cell Biology

ATP Synthase and ATPases ResearchIon Transport and Channel Regulation

Cited by 1,197

Cas9 as a versatile tool for engineering biology

Mali, P., Esvelt, K. M., & Church, G. M. (2013) · Nature Methods

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,197

Development of a self-inactivating lentivirus vector

Miyoshi, H., Blömer, U., Takahashi, M., Gage, F. H., & Verma, I. M. (1998) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 1,196

Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence

Glück, S., Guey, B., Gulen, M. F., Wolter, K., Kang, T.-W., Schmacke, N. A., Bridgeman, A., Rehwinkel, J., Zender, L., & Ablasser, A. (2017) · Nature Cell Biology

Telomeres, Telomerase, and Senescenceinterferon and immune responses

Cited by 1,196

Fusion and fission: interlinked processes critical for mitochondrial health

Chan, D. C. (2012) · Annual Review of Genetics

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 1,196

High-throughput discovery of novel developmental phenotypes

The International Mouse Phenotyping Consortium, Dickinson, M. E., Flenniken, A. M., Ji, X., Teboul, L., Wong, M. D., White, J. K., Meehan, T. F., Weninger, W. J., Westerberg, H., et al. (2016) · Nature

Genomics and Rare DiseasesZebrafish Biomedical Research Applications

Cited by 1,196