Most cited biochemistry, genetics and molecular biology papers
- Verified
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
Niu, G., Wright, K. L., Huang, M., Song, L., Haura, E., Turkson, J., Zhang, S., Wang, T., Sinibaldi, D., Coppola, D., et al. (2002) · Oncogene
Angiogenesis and VEGF in CancerCytokine Signaling Pathways and Interactions
Cited by 1,207
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A revised airway epithelial hierarchy includes CFTR-expressing ionocytes
Montoro, D. T., Haber, A. L., Biton, M., Vinarsky, V., Lin, B., Birket, S. E., Yuan, F., Chen, S., Leung, H. M., Villoria, J., et al. (2018) · Nature
Single-cell and spatial transcriptomicsCystic Fibrosis Research Advances
Cited by 1,206
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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
Kiyono, T., Foster, S. A., Koop, J. I., McDougall, J. K., Galloway, D. A., & Klingelhutz, A. J. (1998) · Nature
Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways
Cited by 1,206
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Histone Deacetylase Inhibitors as Anticancer Drugs
Eckschlager, T., Plch, J., Stiborova, M., & Hrabeta, J. (2017) · International Journal of Molecular Sciences
Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation
Cited by 1,206
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Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion
Vasioukhin, V., Bauer, C., Yin, M., & Fuchs, E. (2000) · Cell
Cellular Mechanics and InteractionsCell Adhesion Molecules Research
Cited by 1,205
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Harnessing protein folding neural networks for peptide–protein docking
Tsaban, T., Varga, J. K., Avraham, O., Ben-Aharon, Z., Khramushin, A., & Schueler-Furman, O. (2022) · Nature Communications
Protein Structure and DynamicsComputational Drug Discovery Methods
Cited by 1,205
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The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal
Zhao, B., Tumaneng, K., & Guan, K.-L. (2011) · Nature Cell Biology
Hippo pathway signaling and YAP/TAZMicrotubule and mitosis dynamics
Cited by 1,205
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Mutations in myostatin ( GDF8 ) in Double-Muscled Belgian Blue and Piedmontese Cattle
Kambadur, R., Sharma, M., Smith, T. P. L., & Bass, J. J. (1997) · Genome Research
Genetic and phenotypic traits in livestockMuscle Physiology and Disorders
Cited by 1,204
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Dynamics of the human gut microbiome in inflammatory bowel disease
Halfvarson, J., Brislawn, C. J., Lamendella, R., Vázquez-Baeza, Y., Walters, W. A., Bramer, L. M., D'Amato, M., Bonfiglio, F., McDonald, D., Gonzalez, A., et al. (2017) · Nature Microbiology
Gut microbiota and healthInflammatory Bowel Disease
Cited by 1,204
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The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases
Caspi, R., Altman, T., Billington, R., Dreher, K., Foerster, H., Fulcher, C. A., Holland, T. A., Keseler, I. M., Kothari, A., Kubo, A., et al. (2014) · Nucleic Acids Research
Bioinformatics and Genomic NetworksMicrobial Metabolic Engineering and Bioproduction
Cited by 1,204
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The effects of alternate optimal solutions in constraint-based genome-scale metabolic models
Mahadevan, R., & Schilling, C. H. (2003) · Metabolic Engineering
Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis
Cited by 1,203
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Molecular inflammation: Underpinnings of aging and age-related diseases
Chung, H. Y., Cesari, M., Anton, S., Marzetti, E., Giovannini, S., Seo, A. Y., Carter, C., Yu, B. P., & Leeuwenburgh, C. (2009) · Ageing Research Reviews
Genetics, Aging, and Longevity in Model OrganismsExercise and Physiological Responses
Cited by 1,203
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A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
Yao, Z., van Velthoven, C. T. J., Kunst, M., Zhang, M., McMillen, D., Lee, C., Jung, W., Goldy, J., Abdelhak, A., Aitken, M., et al. (2023) · Nature
Single-cell and spatial transcriptomicsCell Image Analysis Techniques
Cited by 1,203
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Gut microbiota and aging
O’Toole, P. W., & Jeffery, I. B. (2015) · Science
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,202
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DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
Peterson, T. R., Laplante, M., Thoreen, C. C., Sancak, Y., Kang, S. A., Kuehl, W. M., Gray, N. S., & Sabatini, D. M. (2009) · Cell
PI3K/AKT/mTOR signaling in cancerMultiple Myeloma Research and Treatments
Cited by 1,202
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Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters
Mosser, J., Douar, A.-M., Sarde, C.-O., Kioschis, P., Feil, R., Moser, H., Poustka, A.-M., Mandel, J.-L., & Aubourg, P. (1993) · Nature
Metabolism and Genetic DisordersHereditary Neurological Disorders
Cited by 1,202
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Identity of Osteoclastogenesis Inhibitory Factor (OCIF) and Osteoprotegerin (OPG): A Mechanism by which OPG/OCIF Inhibits Osteoclastogenesis in Vitro1
Yasuda, H., Shima, N., Nakagawa, N., Mochizuki, S.-I., Yano, K., Fujise, N., Sato, Y., Goto, M., Yamaguchi, K., Kuriyama, M., et al. (1998) · Endocrinology
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 1,201
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Structural Variation in the Human Genome and its Role in Disease
Stankiewicz, P., & Lupski, J. R. (2010) · Annual Review of Medicine
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 1,201
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Receptor downregulation and multivesicular-body sorting
Katzmann, D. J., Odorizzi, G., & Emr, S. D. (2002) · Nature Reviews Molecular Cell Biology
Cellular transport and secretionUbiquitin and proteasome pathways
Cited by 1,201
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Interaction network containing conserved and essential protein complexes in Escherichia coli
Butland, G., Peregrín-Alvarez, J. M., Li, J., Yang, W., Yang, X., Canadien, V., Starostine, A., Richards, D., Beattie, B., Krogan, N., et al. (2005) · Nature
Bacterial Genetics and BiotechnologyAdvanced Proteomics Techniques and Applications
Cited by 1,201
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Exploring treatment options in cancer: tumor treatment strategies
Liu, B., Zhou, H., Tan, L., Siu, K. T. H., & Guan, X.-Y. (2024) · Signal Transduction and Targeted Therapy
Cancer Mechanisms and TherapyCancer Immunotherapy and Biomarkers
Cited by 1,201
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Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure
Oka, T., Hikoso, S., Yamaguchi, O., Taneike, M., Takeda, T., Tamai, T., Oyabu, J., Murakawa, T., Nakayama, H., Nishida, K., et al. (2012) · Nature
Autophagy in Disease and TherapyCardiac Fibrosis and Remodeling
Cited by 1,201
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Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
Cassidy-Stone, A., Chipuk, J. E., Ingerman, E., Song, C., Yoo, C., Kuwana, T., Kurth, M. J., Shaw, J. T., Hinshaw, J. E., Green, D. R., et al. (2008) · Developmental Cell
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 1,200
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The microbiome, cancer, and cancer therapy
Helmink, B. A., Khan, M. A. W., Hermann, A., Gopalakrishnan, V., & Wargo, J. A. (2019) · Nature Medicine
Gut microbiota and healthCancer Immunotherapy and Biomarkers
Cited by 1,200
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