Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Genetic screens in human cells using the CRISPR-Cas9 system

Wang, T., Wei, J. J., Sabatini, D. M., & Lander, E. S. (2014) · Science

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 2,856

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

Alberti, S., Gladfelter, A., & Mittag, T. (2019) · Cell

RNA Research and SplicingProtein Structure and Dynamics

Cited by 2,856

Blooms like it hot

Paerl, H. W., & Huisman, J. (2008) · Science

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 2,854

Predicting splicing from primary sequence with deep learning

Jaganathan, K., Kyriazopoulou Panagiotopoulou, S., McRae, J. F., Darbandi, S. F., Knowles, D., Li, Y. I., Kosmicki, J. A., Arbelaez, J., Cui, W., Schwartz, G. B., et al. (2019) · Cell

RNA Research and SplicingGenomics and Rare Diseases

Cited by 2,853

An Expanded View of Complex Traits: From Polygenic to Omnigenic

Boyle, E. A., Li, Y. I., & Pritchard, J. K. (2017) · Cell

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 2,851

A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

Bowie, J. U., Lüthy, R., & Eisenberg, D. (1991) · Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 2,851

A General Empirical Model of Protein Evolution Derived from Multiple Protein Families Using a Maximum-Likelihood Approach

Whelan, S., & Goldman, N. (2001) · Molecular Biology and Evolution

Genomics and Phylogenetic StudiesRNA and protein synthesis mechanisms

Cited by 2,849

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Coll, R. C., Robertson, A. A. B., Chae, J. J., Higgins, S. C., Muñoz-Planillo, R., Inserra, M. C., Vetter, I., Dungan, L. S., Monks, B. G., Stutz, A., et al. (2015) · Nature Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,849

Ancient Admixture in Human History

Patterson, N., Moorjani, P., Luo, Y., Mallick, S., Rohland, N., Zhan, Y., Genschoreck, T., Webster, T., & Reich, D. (2012) · Genetics

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 2,848

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Rea, S., Eisenhaber, F., O'Carroll, D., Strahl, B. D., Sun, Z.-W., Schmid, M., Opravil, S., Mechtler, K., Ponting, C. P., Allis, C. D., et al. (2000) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,845

MAPK signal pathways in the regulation of cell proliferation in mammalian cells

ZHANG, W., & LIU, H. T. (2002) · Cell Research

Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways

Cited by 2,845

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

Saxena, R., Voight, B. F., Lyssenko, V., Burtt, N. P., de Bakker, P. I. W., Chen, H., Roix, J. J., Kathiresan, S., Hirschhorn, J. N., Daly, M. J., et al. (2007) · Science

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,843

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

The Tabula Muris Consortium, coordination, O., coordination, L., processing, O. C. A., sequencing, L. P. A., analysis, C. D., annotation, C. T., Writing group, Supplemental text writing group, & Principal investigators (2018) · Nature

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 2,842

Clonal heterogeneity and tumor evolution: past, present, and the future

McGranahan, N., & Swanton, C. (2017) · Cell

Cancer Genomics and DiagnosticsCancer Cells and Metastasis

Cited by 2,840

Non-Photochemical Quenching. A Response to Excess Light Energy

Müller, P., Li, X.-P., & Niyogi, K. K. (2001) · Plant Physiology

Photosynthetic Processes and MechanismsLight effects on plants

Cited by 2,840

Apoptosis in cancer: from pathogenesis to treatment

Wong, R. S. (2011) · Journal of Experimental & Clinical Cancer Research

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 2,836

A reference panel of 64,976 haplotypes for genotype imputation

the Haplotype Reference Consortium (2016) · Nature Genetics

Genetic Associations and EpidemiologyForensic and Genetic Research

Cited by 2,836

Cell-cycle checkpoints and cancer

Kastan, M. B., & Bartek, J. (2004) · Nature

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 2,836

Defining the role of mTOR in cancer

Guertin, D. A., & Sabatini, D. M. (2007) · Cancer Cell

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,833

The Genomic Landscapes of Human Breast and Colorectal Cancers

Wood, L. D., Parsons, D. W., Jones, S., Lin, J., Sjöblom, T., Leary, R. J., Shen, D., Boca, S. M., Barber, T., Ptak, J., et al. (2007) · Science

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 2,833

Routes and mechanisms of extracellular vesicle uptake

Mulcahy, L. A., Pink, R. C., & Carter, D. R. F. (2014) · Journal of Extracellular Vesicles

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 2,832

Biological Functions of Autophagy Genes: A Disease Perspective

Levine, B., & Kroemer, G. (2019) · Cell

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,832

Bile salt biotransformations by human intestinal bacteria

Ridlon, J. M., Kang, D.-J., & Hylemon, P. B. (2006) · Journal of Lipid Research

Gut microbiota and healthSteroid Chemistry and Biochemistry

Cited by 2,829

AUGUSTUS: ab initio prediction of alternative transcripts

Stanke, M., Keller, O., Gunduz, I., Hayes, A., Waack, S., & Morgenstern, B. (2006) · Nucleic Acids Research

Genomics and Phylogenetic StudiesRNA Research and Splicing

Cited by 2,829