Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Strong association of de novo copy number mutations with autism

Sebat, J., Lakshmi, B., Malhotra, D., Troge, J., Lese-Martin, C., Walsh, T., Yamrom, B., Yoon, S., Krasnitz, A., Kendall, J., et al. (2007) · Science

Genomic variations and chromosomal abnormalitiesAutism Spectrum Disorder Research

Cited by 2,795

A survey of telomerase activity in human cancer

Shay, J. W., & Bacchetti, S. (1997) · European Journal of Cancer

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 2,794

A survey of best practices for RNA-seq data analysis

Conesa, A., Madrigal, P., Tarazona, S., Gomez-Cabrero, D., Cervera, A., McPherson, A., Szcześniak, M. W., Gaffney, D. J., Elo, L. L., Zhang, X., et al. (2016) · Genome Biology

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 2,794

Signalling pathways of the TNF superfamily: a double-edged sword

Aggarwal, B. B. (2003) · Nature Reviews Immunology

NF-κB Signaling PathwaysCytokine Signaling Pathways and Interactions

Cited by 2,793

High-throughput droplet digital PCR system for absolute quantitation of DNA copy number

Hindson, B. J., Ness, K. D., Masquelier, D. A., Belgrader, P., Heredia, N. J., Makarewicz, A. J., Bright, I. J., Lucero, M. Y., Hiddessen, A. L., Legler, T. C., et al. (2011) · Analytical Chemistry

Molecular Biology Techniques and ApplicationsInnovative Microfluidic and Catalytic Techniques Innovation

Cited by 2,792

The gut flora as a forgotten organ

O'Hara, A. M., & Shanahan, F. (2006) · The EMBO Reports

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 2,791

An approximately unbiased test of phylogenetic tree selection

Shimodaira, H. (2002) · Systematic Biology

Genomics and Phylogenetic StudiesGenetic diversity and population structure

Cited by 2,791

Phosphoinositides in cell regulation and membrane dynamics

Di Paolo, G., & De Camilli, P. (2006) · Nature

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 2,790

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

Roberts, P. J., & Der, C. J. (2007) · Oncogene

Melanoma and MAPK PathwaysProtein Kinase Regulation and GTPase Signaling

Cited by 2,788

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S., et al. (1995) · Science

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 2,785

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

van Zundert, G. C. P., Rodrigues, J. P. G. L. M., Trellet, M., Schmitz, C., Kastritis, P. L., Karaca, E., Melquiond, A. S. J., van Dijk, M., de Vries, S. J., & Bonvin, A. M. J. J. (2016) · Journal of Molecular Biology

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 2,785

Processing of primary microRNAs by the Microprocessor complex

Denli, A. M., Tops, B. B. J., Plasterk, R. H. A., Ketting, R. F., & Hannon, G. J. (2004) · Nature

MicroRNA in disease regulationPlant Molecular Biology Research

Cited by 2,784

A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

Hutvágner, G., McLachlan, J., Pasquinelli, A. E., Bálint, E., Tuschl, T., & Zamore, P. D. (2001) · Science

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 2,781

Potential, impedance, and rectification in membranes

Goldman, D. E. (1943) · Journal of General Physiology

Ion channel regulation and functionIon Transport and Channel Regulation

Cited by 2,777

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Lazarou, M., Sliter, D. A., Kane, L. A., Sarraf, S. A., Wang, C., Burman, J. L., Sideris, D. P., Fogel, A. I., & Youle, R. J. (2015) · Nature

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 2,774

Role of reactive oxygen species (ROS) in apoptosis induction

Simon, H.-U., Haj-Yehia, A., & Levi-Schaffer, F. (2000) · Apoptosis

Cell death mechanisms and regulationRedox biology and oxidative stress

Cited by 2,774

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Sancak, Y., Peterson, T. R., Shaul, Y. D., Lindquist, R. A., Thoreen, C. C., Bar-Peled, L., & Sabatini, D. M. (2008) · Science

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,773

MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer

Meng, F., Henson, R., Wehbe–Janek, H., Ghoshal, K., Jacob, S. T., & Patel, T. (2007) · Gastroenterology

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 2,773

Mechanism and medical implications of mammalian autophagy

Dikic, I., & Elazar, Z. (2018) · Nature Reviews Molecular Cell Biology

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 2,771

Pore-forming activity and structural autoinhibition of the gasdermin family

Ding, J., Wang, K., Liu, W., She, Y., Sun, Q., Shi, J., Sun, H., Wang, D.-C., & Shao, F. (2016) · Nature

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 2,771

Basic and Therapeutic Aspects of Angiogenesis

Potente, M., Gerhardt, H., & Carmeliet, P. (2011) · Cell

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 2,771

RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays

Marioni, J. C., Mason, C. E., Mane, S. M., Stephens, M., & Gilad, Y. (2008) · Genome Research

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 2,771

Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

Gasiunas, G., Barrangou, R., Horvath, P., & Siksnys, V. (2012) · Proceedings of the National Academy of Sciences

CRISPR and Genetic EngineeringBacterial Genetics and Biotechnology

Cited by 2,769

The complex language of chromatin regulation during transcription

Berger, S. L. (2007) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,768