Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Metabolomics: beyond biomarkers and towards mechanisms

Johnson, C. H., Ivanisevic, J., & Siuzdak, G. (2016) · Nature Reviews Molecular Cell Biology

Metabolomics and Mass Spectrometry StudiesBioinformatics and Genomic Networks

Cited by 2,829

An Introduction to Systems Biology: Design Principles of Biological Circuits

Alon, U. (2006) · Chapman & Hall/CRC eBooks

Gene Regulatory Network AnalysisMicrobial Metabolic Engineering and Bioproduction

Cited by 2,825

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

Konermann, S., Brigham, M. D., Trevino, A. E., Joung, J., Abudayyeh, O. O., Barcena, C., Hsu, P. D., Habib, N., Gootenberg, J. S., Nishimasu, H., et al. (2015) · Nature

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 2,825

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

Martin, S. J., Reutelingsperger, C. P., McGahon, A. J., Rader, J. A., van Schie, R. C., LaFace, D. M., & Green, D. R. (1995) · The Journal of experimental medicine

Cell death mechanisms and regulationPhagocytosis and Immune Regulation

Cited by 2,824

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Christofk, H. R., Vander Heiden, M. G., Harris, M. H., Ramanathan, A., Gerszten, R. E., Wei, R., Fleming, M. D., Schreiber, S. L., & Cantley, L. C. (2008) · Nature

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 2,820

Cellular senescence: from physiology to pathology

Muñoz-Espín, D., & Serrano, M. (2014) · Nature Reviews Molecular Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 2,818

Variance component model to account for sample structure in genome-wide association studies

Kang, H. M., Sul, J. H., Service, S. K., Zaitlen, N. A., Kong, S.-Y., Freimer, N. B., Sabatti, C., & Eskin, E. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,817

Mitochondrial TCA cycle metabolites control physiology and disease

Martínez-Reyes, I., & Chandel, N. S. (2020) · Nature Communications

Mitochondrial Function and PathologyCancer, Hypoxia, and Metabolism

Cited by 2,813

Database resources of the national center for biotechnology information

Sayers, E. W., Bolton, E. E., Brister, J. R., Canese, K., Chan, J., Comeau, D. C., Connor, R., Funk, K., Kelly, C., Kim, S., et al. (2022) · Nucleic Acids Research

Genomics and Phylogenetic StudiesGenetics, Bioinformatics, and Biomedical Research

Cited by 2,812

Arginine metabolism: nitric oxide and beyond

WU, G., & MORRIS, S. M. (1998) · Biochemical Journal

Amino Acid Enzymes and MetabolismPolyamine Metabolism and Applications

Cited by 2,811

Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations

Flaherty, K. T., Infante, J. R., Daud, A., Gonzalez, R., Kefford, R. F., Sosman, J., Hamid, O., Schuchter, L., Cebon, J., Ibrahim, N., et al. (2012) · New England Journal of Medicine

Melanoma and MAPK PathwaysColorectal Cancer Treatments and Studies

Cited by 2,810

The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies

Juan, C. A., Pérez de la Lastra, J. M., Plou, F. J., & Pérez-Lebeña, E. (2021) · International Journal of Molecular Sciences

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 2,810

Liquid biopsies come of age: Towards implementation of circulating tumour DNA

Wan, J. C. M., Massie, C., Garcia-Corbacho, J., Mouliere, F., Brenton, J. D., Caldas, C., Pacey, S., Baird, R., & Rosenfeld, N. (2017) · Nature Reviews Cancer

Cancer Genomics and DiagnosticsPrenatal Screening and Diagnostics

Cited by 2,809

The molecular hallmarks of epigenetic control

Allis, C. D., & Jenuwein, T. (2016) · Nature Reviews Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,809

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

Ro, D.-K., Paradise, E. M., Ouellet, M., Fisher, K. J., Newman, K. L., Ndungu, J. M., Ho, K. A., Eachus, R. A., Ham, T. S., Kirby, J., et al. (2006) · Nature

Plant biochemistry and biosynthesisMicrobial Metabolic Engineering and Bioproduction

Cited by 2,805

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

Desai, M. S., Seekatz, A. M., Koropatkin, N. M., Kamada, N., Hickey, C. A., Wolter, M., Pudlo, N. A., Kitamoto, S., Terrapon, N., Muller, A., et al. (2016) · Cell

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 2,805

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Land, H., Parada, L. F., & Weinberg, R. A. (1983) · Nature

Protein Kinase Regulation and GTPase SignalingCancer-related Molecular Pathways

Cited by 2,804

TGF-β-induced epithelial to mesenchymal transition

Xu, J., Lamouille, S., & Derynck, R. (2009) · Cell Research

TGF-β signaling in diseasesCancer Cells and Metastasis

Cited by 2,804

Flow-mediated endothelial mechanotransduction

Davies, P. F. (1995) · Physiological Reviews

Cellular Mechanics and InteractionsElasticity and Material Modeling

Cited by 2,802

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

Hotamisligil, G. S. (2010) · Cell

Endoplasmic Reticulum Stress and DiseaseAdipokines, Inflammation, and Metabolic Diseases

Cited by 2,802

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

Kahn, B. B., Alquier, T., Carling, D., & Hardie, D. G. (2005) · Cell Metabolism

Metabolism, Diabetes, and CancerAdipokines, Inflammation, and Metabolic Diseases

Cited by 2,799

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Bergers, G., Brekken, R., McMahon, G., Vu, T. H., Itoh, T., Tamaki, K., Tanzawa, K., Thorpe, P., Itohara, S., Werb, Z., et al. (2000) · Nature Cell Biology

Angiogenesis and VEGF in CancerProtease and Inhibitor Mechanisms

Cited by 2,797

Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy

Ryan, C. J., Smith, M. R., de Bono, J. S., Molina, A., Logothetis, C. J., de Souza, P., Fizazi, K., Mainwaring, P., Piulats, J. M., Ng, S., et al. (2013) · New England Journal of Medicine

Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment

Cited by 2,796

Argonaute2 is the catalytic engine of mammalian RNAi

Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., Song, J.-J., Hammond, S. M., Joshua-Tor, L., & Hannon, G. J. (2004) · Science

RNA Interference and Gene DeliveryRNA Research and Splicing

Cited by 2,796