Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

Sun, L., Wang, H., Wang, Z., He, S., Chen, S., Liao, D., Wang, L., Yan, J., Liu, W., Lei, X., et al. (2012) · Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 2,698

Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development

O'Toole, G. A., & Kolter, R. (1998) · Molecular Microbiology

Bacterial biofilms and quorum sensingBiochemical and Structural Characterization

Cited by 2,697

The Pfam protein families database

Finn, R. D., Mistry, J., Tate, J., Coggill, P., Heger, A., Pollington, J. E., Gavin, O. L., Gunasekaran, P., Ceric, G., Forslund, K., et al. (2010) · Nucleic Acids Research

Genomics and Phylogenetic StudiesMachine Learning in Bioinformatics

Cited by 2,694

Approximate likelihood-ratio test for branches: A fast, accurate, and powerful alternative

Anisimova, M., & Gascuel, O. (2006) · Systematic Biology

Genomics and Phylogenetic StudiesRNA and protein synthesis mechanisms

Cited by 2,693

Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Zou, L., & Elledge, S. J. (2003) · Science

DNA Repair MechanismsFungal and yeast genetics research

Cited by 2,693

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

Costa-Silva, B., Aiello, N. M., Ocean, A. J., Singh, S., Zhang, H., Thakur, B. K., Becker, A., Hoshino, A., Mark, M. T., Molina, H., et al. (2015) · Nature Cell Biology

Extracellular vesicles in diseasePancreatic and Hepatic Oncology Research

Cited by 2,692

A microRNA component of the p53 tumour suppressor network

He, L., He, X., Lim, L. P., de Stanchina, E., Xuan, Z., Liang, Y., Xue, W., Zender, L., Magnus, J., Ridzon, D., et al. (2007) · Nature

MicroRNA in disease regulationCancer-related Molecular Pathways

Cited by 2,692

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Bartkova, J., Hořejší, Z., Koed, K., Krämer, A., Tort, F., Zieger, K., Guldberg, P., Sehested, M., Nesland, J. M., Lukas, C., et al. (2005) · Nature

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 2,688

In vivo genome editing using Staphylococcus aureus Cas9

Ran, F. A., Cong, L., Yan, W. X., Scott, D. A., Gootenberg, J. S., Kriz, A. J., Zetsche, B., Shalem, O., Wu, X., Makarova, K. S., et al. (2015) · Nature

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 2,687

Principles of protein-protein interactions

Jones, S., & Thornton, J. M. (1996) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 2,684

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

Li, W., Xu, H., Xiao, T., Cong, L., Love, M. I., Zhang, F., Irizarry, R. A., Liu, J. S., Brown, M., & Liu, X. S. (2014) · Genome Biology

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 2,684

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N., & Altman, S. (1983) · Cell

RNA and protein synthesis mechanismsRNA modifications and cancer

Cited by 2,684

Exosomes

Pegtel, D. M., & Gould, S. J. (2019) · Annual Review of Biochemistry

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 2,682

NF-κB, inflammation, immunity and cancer: coming of age

Taniguchi, K., & Karin, M. (2018) · Nature Reviews Immunology

NF-κB Signaling PathwaysSignaling Pathways in Disease

Cited by 2,679

RING Domain E3 Ubiquitin Ligases

Deshaies, R. J., & Joazeiro, C. A. P. (2009) · Annual Review of Biochemistry

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 2,679

The accessible chromatin landscape of the human genome

Thurman, R. E., Rynes, E., Humbert, R., Vierstra, J., Maurano, M. T., Haugen, E., Sheffield, N. C., Stergachis, A. B., Wang, H., Vernot, B., et al. (2012) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 2,679

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

Wikoff, W. R., Anfora, A. T., Liu, J., Schultz, P. G., Lesley, S. A., Peters, E. C., & Siuzdak, G. (2009) · Proceedings of the National Academy of Sciences

Gut microbiota and healthMetabolomics and Mass Spectrometry Studies

Cited by 2,677

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects

Kleinstiver, B. P., Pattanayak, V., Prew, M. S., Tsai, S. Q., Nguyen, N. T., Zheng, Z., & Joung, J. K. (2016) · Nature

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 2,673

Mechanisms, regulation and functions of the unfolded protein response

Hetz, C., Zhang, K., & Kaufman, R. J. (2020) · Nature Reviews Molecular Cell Biology

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 2,666

The Spliceosome: Design Principles of a Dynamic RNP Machine

Wahl, M. C., Will, C. L., & Lührmann, R. (2009) · Cell

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 2,665

Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Sarbassov, D. D., Ali, S. M., Kim, D.-H., Guertin, D. A., Latek, R. R., Erdjument-Bromage, H., Tempst, P., & Sabatini, D. M. (2004) · Current Biology

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 2,665

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA

Warren, L., Manos, P. D., Ahfeldt, T., Loh, Y.-H., Li, H., Lau, F., Ebina, W., Mandal, P. K., Smith, Z. D., Meissner, A., et al. (2010) · Cell Stem Cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 2,662

Tumor Hypoxia: Definitions and Current Clinical, Biologic, and Molecular Aspects

Hockel, M., & Vaupel, P. (2001) · JNCI Journal of the National Cancer Institute

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 2,662

The mechanisms of action of PPARs

Berger, J., & Moller, D. E. (2002) · Annual Review of Medicine

Peroxisome Proliferator-Activated ReceptorsCholesterol and Lipid Metabolism

Cited by 2,659