Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

The integrated stress response

Pakos‐Zebrucka, K., Koryga, I., Mnich, K., Ljujic, M., Samali, A., & Gorman, A. M. (2016) · The EMBO Reports

Endoplasmic Reticulum Stress and DiseaseRNA and protein synthesis mechanisms

Cited by 2,659

Definition and Impact of Pathologic Complete Response on Prognosis After Neoadjuvant Chemotherapy in Various Intrinsic Breast Cancer Subtypes

von Minckwitz, G., Untch, M., Blohmer, J.-U., Costa, S. D., Eidtmann, H., Fasching, P. A., Gerber, B., Eiermann, W., Hilfrich, J., Huober, J., et al. (2012) · Journal of Clinical Oncology

Breast Cancer Treatment StudiesBreast Lesions and Carcinomas

Cited by 2,659

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

Dostert, C., Pétrilli, V., Van Bruggen, R., Steele, C., Mossman, B. T., & Tschopp, J. (2008) · Science

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,658

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

Vandanmagsar, B., Youm, Y.-H., Ravussin, A., Galgani, J. E., Stadler, K., Mynatt, R. L., Ravussin, E., Stephens, J. M., & Dixit, V. D. (2011) · Nature Medicine

Inflammasome and immune disordersAdipokines, Inflammation, and Metabolic Diseases

Cited by 2,655

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

Nguyen, T., Nioi, P., & Pickett, C. B. (2009) · Journal of Biological Chemistry

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 2,655

Oxidative Stress in Cancer

Hayes, J. D., Dinkova-Kostova, A. T., & Tew, K. D. (2020) · Cancer Cell

Redox biology and oxidative stressCancer, Hypoxia, and Metabolism

Cited by 2,654

Angiogenesis as a therapeutic target

Ferrara, N., & Kerbel, R. S. (2005) · Nature

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 2,653

A framework for human microbiome research

The Human Microbiome Project Consortium (2012) · Nature

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 2,650

Funnels, pathways, and the energy landscape of protein folding: A synthesis

Bryngelson, J. D., Onuchic, J. N., Socci, N. D., & Wolynes, P. G. (1995) · Proteins: Structure, Function, and Bioinformatics

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 2,648

Functional siRNAs and miRNAs exhibit strand bias

Khvorova, A., Reynolds, A., & Jayasena, S. D. (2003) · Cell

RNA Interference and Gene DeliveryRNA and protein synthesis mechanisms

Cited by 2,645

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

Dietzl, G., Chen, D., Schnorrer, F., Su, K.-C., Barinova, Y., Fellner, M., Gasser, B., Kinsey, K., Oppel, S., Scheiblauer, S., et al. (2007) · Nature

RNA Interference and Gene DeliveryNeurobiology and Insect Physiology Research

Cited by 2,644

Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks

Khan, J., Wei, J. S., Ringnér, M., Saal, L. H., Ladanyi, M., Westermann, F., Berthold, F., Schwab, M., Antonescu, C. R., Peterson, C., et al. (2001) · Nature Medicine

Gene expression and cancer classificationBreast Cancer Treatment Studies

Cited by 2,644

MetaWRAP—a flexible pipeline for genome-resolved metagenomic data analysis

Uritskiy, G. V., DiRuggiero, J., & Taylor, J. (2018) · Microbiome

Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology

Cited by 2,642

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

Kamerkar, S., LeBleu, V. S., Sugimoto, H., Yang, S., Ruivo, C. F., Melo, S. A., Lee, J. J., & Kalluri, R. (2017) · Nature

Extracellular vesicles in diseaseRNA Interference and Gene Delivery

Cited by 2,639

Mapping short DNA sequencing reads and calling variants using mapping quality scores

Li, H., Ruan, J., & Durbin, R. (2008) · Genome Research

Genomics and Phylogenetic StudiesAlgorithms and Data Compression

Cited by 2,638

Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

Gibson, D. G., Glass, J. I., Lartigue, C., Noskov, V. N., Chuang, R.-Y., Algire, M. A., Benders, G. A., Montague, M. G., Ma, L., Moodie, M. M., et al. (2010) · Science

Microbial Metabolic Engineering and BioproductionRNA and protein synthesis mechanisms

Cited by 2,638

Epigenetics in cancer

Sharma, S., Kelly, T. K., & Jones, P. A. (2010) · Carcinogenesis

Epigenetics and DNA MethylationCancer-related molecular mechanisms research

Cited by 2,637

Glutathione: overview of its protective roles, measurement, and biosynthesis

Forman, H. J., Zhang, H., & Rinna, A. (2009) · Molecular Aspects of Medicine

Sulfur Compounds in BiologyRedox biology and oxidative stress

Cited by 2,636

NCBI Taxonomy: a comprehensive update on curation, resources and tools

Schoch, C. L., Ciufo, S., Domrachev, M., Hotton, C. L., Kannan, S., Khovanskaya, R., Leipe, D., Mcveigh, R., O’Neill, K., Robbertse, B., et al. (2020) · Database

Genomics and Phylogenetic StudiesBiomedical Text Mining and Ontologies

Cited by 2,635

Biological roles of glycans

Varki, A. (2017) · Glycobiology

Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and Synthesis

Cited by 2,635

SNAREs — engines for membrane fusion

Jahn, R., & Scheller, R. H. (2006) · Nature Reviews Molecular Cell Biology

Cellular transport and secretionLipid Membrane Structure and Behavior

Cited by 2,635

Physiological Roles of Mitochondrial Reactive Oxygen Species

Sena, L. A., & Chandel, N. S. (2012) · Molecular Cell

Redox biology and oxidative stressMitochondrial Function and Pathology

Cited by 2,632

Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade

Chiti, F., & Dobson, C. M. (2017) · Annual Review of Biochemistry

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 2,629

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Hornung, V., Ablasser, A., Charrel-Dennis, M., Bauernfeind, F., Horvath, G., Caffrey, D. R., Latz, E., & Fitzgerald, K. A. (2009) · Nature

Inflammasome and immune disordersinterferon and immune responses

Cited by 2,627