Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers

Peng, L., Li, Z.-R., Green, R. S., Holzmanr, I. R., & Lin, J. (2009) · The Journal of Nutrition

Gut microbiota and healthBarrier Structure and Function Studies

Cited by 2,130

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

Heery, D. M., Kalkhoven, E., Hoare, S., & Parker, M. G. (1997) · Nature

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 2,128

Identification of Mammalian microRNA Host Genes and Transcription Units

Rodriguez, A., Griffiths-Jones, S., Ashurst, J. L., & Bradley, A. (2004) · Genome Research

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 2,128

A guide to machine learning for biologists

Greener, J. G., Kandathil, S. M., Moffat, L., & Jones, D. T. (2022) · Nature Reviews Molecular Cell Biology

Machine Learning in BioinformaticsGene expression and cancer classification

Cited by 2,127

The mechanism of action of cyclosporin A and FK506

Schreiber, S. L., & Crabtree, G. R. (1992) · Immunology Today

Signaling Pathways in DiseaseT-cell and B-cell Immunology

Cited by 2,127

MTOR: a pharmacologic target for autophagy regulation

Kim, Y. C., & Guan, K.-L. (2015) · Journal of Clinical Investigation

PI3K/AKT/mTOR signaling in cancerAutophagy in Disease and Therapy

Cited by 2,126

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

MAQC Consortium, Shi, L., Shi, L., Reid, L. H., Jones, W. D., Shippy, R., Warrington, J. A., Baker, S. C., Collins, P. J., de Longueville, F., et al. (2006) · Nature Biotechnology

Gene expression and cancer classificationMolecular Biology Techniques and Applications

Cited by 2,126

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., & Karin, M. (1997) · Nature

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 2,125

FGF-21 as a novel metabolic regulator

Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., et al. (2005) · Journal of Clinical Investigation

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 2,125

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J.-I., & Chen, Z. J. (2001) · Nature

NF-κB Signaling PathwaysUbiquitin and proteasome pathways

Cited by 2,125

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

Komatsu, M., Waguri, S., Koike, M., Sou, Y.-S., Ueno, T., Hara, T., Mizushima, N., Iwata, J.-I., Ezaki, J., Murata, S., et al. (2007) · Cell

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 2,124

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Gao, P., Tchernyshyov, I., Chang, T.-C., Lee, Y.-S., Kita, K., Ochi, T., Zeller, K. I., De Marzo, A. M., Van Eyk, J. E., Mendell, J. T., et al. (2009) · Nature

Cancer, Hypoxia, and MetabolismMicroRNA in disease regulation

Cited by 2,124

The mystery of membrane organization: composition, regulation and roles of lipid rafts

Sezgin, E., Levental, I., Mayor, S., & Eggeling, C. (2017) · Nature Reviews Molecular Cell Biology

Lipid Membrane Structure and BehaviorCaveolin-1 and cellular processes

Cited by 2,124

Cellular Fatty Acid Metabolism and Cancer

Currie, E., Schulze, A., Zechner, R., Walther, T. C., & Farese, R. V. (2013) · Cell Metabolism

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

Cited by 2,123

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

Mauthe, M., Orhon, I., Rocchi, C., Zhou, X., Luhr, M., Hijlkema, K.-J., Coppes, R. P., Engedal, N., Mari, M., & Reggiori, F. (2018) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 2,122

Role of Mitochondria in Ferroptosis

Gao, M., Yi, J., Zhu, J., Minikes, A. M., Monian, P., Thompson, C. B., & Jiang, X. (2019) · Molecular Cell

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 2,120

Multiple Pathways of Recombination Induced by Double-Strand Breaks in Saccharomyces cerevisiae

Pâques, F., & Haber, J. E. (1999) · Microbiology and Molecular Biology Reviews

DNA Repair MechanismsFungal and yeast genetics research

Cited by 2,120

Exosomes: biogenesis, biologic function and clinical potential

Zhang, Y., Liu, Y., Liu, H., & Tang, W. H. (2019) · Cell & Bioscience

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 2,119

From Krebs to clinic: glutamine metabolism to cancer therapy

Altman, B. J., Stine, Z. E., & Dang, C. V. (2016) · Nature Reviews Cancer

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 2,119

Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

Rissin, D. M., Kan, C. W., Campbell, T. G., Howes, S. C., Fournier, D. R., Song, L., Piech, T., Patel, P. P., Chang, L., Rivnak, A. J., et al. (2010) · Nature Biotechnology

Advanced Biosensing Techniques and ApplicationsAdvanced Fluorescence Microscopy Techniques

Cited by 2,119

Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)

Cheng, D. T., Mitchell, T. N., Zehir, A., Shah, R. H., Benayed, R., Syed, A., Chandramohan, R., Liu, Z. Y., Won, H. H., Scott, S. N., et al. (2015) · The Journal of Molecular Diagnostics

Cancer Genomics and DiagnosticsGenomics and Rare Diseases

Cited by 2,119

Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: an in situ hybridization study

Simerly, R. B., Swanson, L. W., Chang, C., & Muramatsu, M. (1990) · Journal of Comparative Neurology

Estrogen and related hormone effectsHypothalamic control of reproductive hormones

Cited by 2,118

Human gut microbes impact host serum metabolome and insulin sensitivity

Pedersen, H. K., Gudmundsdottir, V., Nielsen, H. B., Hyotylainen, T., Nielsen, T., Jensen, B. A. H., Forslund, K., Hildebrand, F., Prifti, E., Falony, G., et al. (2016) · Nature

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 2,116

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

Forman, B. M., Chen, J., & Evans, R. M. (1997) · Proceedings of the National Academy of Sciences

Peroxisome Proliferator-Activated ReceptorsFatty Acid Research and Health

Cited by 2,116