Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

MetaHIT consortium, Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., et al. (2015) · Nature

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 2,116

Modeling of loops in protein structures

Fiser, A., Do, R. K. G., & Šali, A. (2000) · Protein Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 2,116

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

Yue, Z., Jin, S., Yang, C., Levine, A. J., & Heintz, N. (2003) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyCancer-related Molecular Pathways

Cited by 2,116

Regulation of hypoxia-inducible factor 1α is mediated by an O 2 -dependent degradation domain via the ubiquitin-proteasome pathway

Huang, L. E., Gu, J., Schau, M., & Bunn, H. F. (1998) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 2,113

The population genetic consequences of habitat fragmentation for plants

Young, A., Boyle, T., & Brown, T. (1996) · Trends in Ecology & Evolution

Genetic diversity and population structureEcology and Vegetation Dynamics Studies

Cited by 2,113

Reducing the Effects of PCR Amplification and Sequencing Artifacts on 16S rRNA-Based Studies

Schloss, P. D., Gevers, D., & Westcott, S. L. (2011) · PLoS ONE

Genomics and Phylogenetic StudiesMicrobial Community Ecology and Physiology

Cited by 2,112

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

Oda, E., Ohki, R., Murasawa, H., Nemoto, J., Shibue, T., Yamashita, T., Tokino, T., Taniguchi, T., & Tanaka, †. N. (2000) · Science

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 2,112

Assessing the accuracy of prediction algorithms for classification: an overview

Baldi, P., Brunak, S., Chauvin, Y., Andersen, C. A. F., & Nielsen, H. (2000) · Bioinformatics

Machine Learning in BioinformaticsMachine Learning and Data Classification

Cited by 2,111

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

Singh, R., Letai, A., & Sarosiek, K. (2019) · Nature Reviews Molecular Cell Biology

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 2,111

Phenotypic Plasticity and the Origins of Diversity

West-Eberhard, M. J. (1989) · Annual Review of Ecology and Systematics

Evolution and Genetic DynamicsAnimal Behavior and Reproduction

Cited by 2,110

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Holzenberger, M., Dupont, J., Ducos, B., Leneuve, P., Géloën, A., Even, P. C., Cervera, P., & Le Bouc, Y. (2003) · Nature

Genetics, Aging, and Longevity in Model OrganismsGrowth Hormone and Insulin-like Growth Factors

Cited by 2,109

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase

Selak, M. A., Armour, S. M., MacKenzie, E. D., Boulahbel, H., Watson, D. G., Mansfield, K. D., Pan, Y., Simon, M. C., Thompson, C. B., & Gottlieb, E. (2005) · Cancer Cell

Cancer, Hypoxia, and MetabolismEar and Head Tumors

Cited by 2,108

Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis

Chipuk, J. E., Kuwana, T., Bouchier-Hayes, L., Droin, N. M., Newmeyer, D. D., Schuler, M., & Green, D. R. (2004) · Science

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 2,108

Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

Blasco, M. A., Lee, H.-W., Hande, M. P., Samper, E., Lansdorp, P. M., DePinho, R. A., & Greider, C. W. (1997) · Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 2,108

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., Nowak, N. J., Joyner, A., Leblanc, G., Hatten, M. E., et al. (2003) · Nature

Developmental Biology and Gene RegulationNeurogenesis and neuroplasticity mechanisms

Cited by 2,108

MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells

Ebert, M. S., Neilson, J. R., & Sharp, P. A. (2007) · Nature Methods

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 2,108

Autophagy and Aging

Rubinsztein, D. C., Mariño, G., & Kroemer, G. (2011) · Cell

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 2,107

Macrophage-specific PPARγ controls alternative activation and improves insulin resistance

Odegaard, J. I., Ricardo-Gonzalez, R. R., Goforth, M. H., Morel, C. R., Subramanian, V., Mukundan, L., Eagle, A. R., Vats, D., Brombacher, F., Ferrante, A. W., et al. (2007) · Nature

Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 2,107

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

Petersen, K. F., Befroy, D., Dufour, S., Dziura, J., Ariyan, C., Rothman, D. L., DiPietro, L., Cline, G. W., & Shulman, G. I. (2003) · Science

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 2,107

InterPro: the integrative protein signature database

Hunter, S., Apweiler, R., Attwood, T. K., Bairoch, A., Bateman, A., Binns, D., Bork, P., Das, U., Daugherty, L., Duquenne, L., et al. (2009) · Nucleic Acids Research

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 2,107

Detecting recent positive selection in the human genome from haplotype structure

Sabeti, P. C., Reich, D. E., Higgins, J. M., Levine, H. Z. P., Richter, D. J., Schaffner, S. F., Gabriel, S. B., Platko, J. V., Patterson, N. J., McDonald, G. J., et al. (2002) · Nature

Forensic and Genetic ResearchGenetic Associations and Epidemiology

Cited by 2,106

BODIPY dyes in photodynamic therapy

Kamkaew, A., Lim, S. H., Lee, H. B., Kiew, L. V., Chung, L. Y., & Burgess, K. (2013) · Chem. Soc. Rev.

Photodynamic Therapy Research StudiesLuminescence and Fluorescent Materials

Cited by 2,104

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

Scherz‐Shouval, R., Shvets, E., Fass, E., Shorer, H., Gil, L., & Elazar, Z. (2007) · The EMBO Journal

Autophagy in Disease and TherapyRedox biology and oxidative stress

Cited by 2,101

Mesenchymal stem cell-mediated immunosuppression occurs via concerted action of chemokines and nitric oxide

Ren, G., Zhang, L., Zhao, X., Xu, G., Zhang, Y., Roberts, A. I., Zhao, R. C., & Shi, Y. (2008) · Cell Stem Cell

Mesenchymal stem cell researchHematopoietic Stem Cell Transplantation

Cited by 2,101