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Cited by 552Psychotherapy Techniques and ApplicationsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPersonality Disorders and Psychopathology

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Efficacy of Interpersonal Psychotherapy for Depressed Adolescents

Mufson, L.·1999·Archives of General Psychiatry
DOI 10.1001/archpsyc.56.6.573
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Abstract

BACKGROUND: Psychotherapy is widely used for depressed adolescents, but evidence supporting its efficacy is sparse. METHODS: In a controlled, 12-week, clinical trial of Interpersonal Psychotherapy for Depressed Adolescents (IPT-A), 48 clinic-referred adolescents (aged 12-18 years) who met the criteria for DSM-III-R major depressive disorder were randomly assigned to either weekly IPT-A or clinical monitoring. Patients were seen biweekly by a "blind" independent evaluator to assess their symptoms, social functioning, and social problem-solving skills. Thirty-two of the 48 patients completed the protocol (21 IPT-A-assigned patients and 11 patients in the control group). RESULTS: Patients who received IPT-A reported a notably greater decrease in depressive symptoms and greater improvement in overall social functioning, functioning with friends, and specific problem-solving skills. In the intent-to-treat sample, 18 (75%) of 24 patients who received IPT-A compared with 11 patients (46%) in the control condition met recovery criterion (Hamilton Rating Scale for Depression score < or =6) at week 12. CONCLUSIONS: These preliminary findings support the feasibility, acceptability, and efficacy of 12 weeks of IPT-A in acutely depressed adolescents in reducing depressive symptoms and improving social functioning and interpersonal problem-solving skills. Because it is a small sample consisting largely of Latino, low socioeconomic status adolescents, further studies must be conducted with other adolescent populations to confirm the generalizability of the findings.

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Metadata

Authors
Mufson, L.
Affiliations
New York State Psychiatric Institute (US)
Corresponding author
Mufson, L.
ORCID
Mufson, L.
Venue
Archives of General Psychiatry
Publisher
American Medical Association (AMA)
Published
1999-06-01
Volume
56
Issue
6
Pages
573-579
ISSN
0003-990X (ISSN-L)
DOI
10.1001/archpsyc.56.6.573
OpenAlex
W2158366999
Cited by
552
References
38
Citations by year
2026: 5 · 2025: 3 · 2024: 12 · 2023: 11 · 2022: 13 · 2021: 21 · 2020: 15 · 2019: 12 · 2018: 14 · 2017: 17 · 2016: 18 · 2015: 27 · 2014: 25 · 2013: 18 · 2012: 28
FWCI
23.13
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of General Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (1r01mh043873-01, 5r29mh048715-05)
  • National Institute of Mental Health (MH43873-09, MH48715)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords
interpersonal psychotherapy, adolescent depression, major depressive disorder, social functioning, interpersonal problem-solving skills, depressive symptom reduction, treatment efficacy, Latino adolescents
MeSH terms
Adolescent, Age Factors, Child, Depressive Disorder, Female, Humans, Interpersonal Relations, Male, Patient Dropouts, Problem Solving, Psychiatric Status Rating Scales, Psychotherapy, Research Design, Social Adjustment, Social Class, Treatment Outcome, Patient Selection

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