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Effect of Mindfulness-Based Stress Reduction vs Cognitive Behavioral Therapy or Usual Care on Back Pain and Functional Limitations in Adults With Chronic Low Back Pain: A Randomized Clinical Trial
Open accessAbstract
IMPORTANCE: Mindfulness-based stress reduction (MBSR) has not been rigorously evaluated for young and middle-aged adults with chronic low back pain. OBJECTIVE: To evaluate the effectiveness for chronic low back pain of MBSR vs cognitive behavioral therapy (CBT) or usual care. DESIGN, SETTING, AND PARTICIPANTS: Randomized, interviewer-blind, clinical trial in an integrated health care system in Washington State of 342 adults aged 20 to 70 years with chronic low back pain enrolled between September 2012 and April 2014 and randomly assigned to receive MBSR (n = 116), CBT (n = 113), or usual care (n = 113). INTERVENTIONS: CBT (training to change pain-related thoughts and behaviors) and MBSR (training in mindfulness meditation and yoga) were delivered in 8 weekly 2-hour groups. Usual care included whatever care participants received. MAIN OUTCOMES AND MEASURES: Coprimary outcomes were the percentages of participants with clinically meaningful (≥30%) improvement from baseline in functional limitations (modified Roland Disability Questionnaire [RDQ]; range, 0-23) and in self-reported back pain bothersomeness (scale, 0-10) at 26 weeks. Outcomes were also assessed at 4, 8, and 52 weeks. RESULTS: There were 342 randomized participants, the mean (SD) [range] age was 49.3 (12.3) [20-70] years, 224 (65.7%) were women, mean duration of back pain was 7.3 years (range, 3 months-50 years), 123 (53.7%) attended 6 or more of the 8 sessions, 294 (86.0%) completed the study at 26 weeks, and 290 (84.8%) completed the study at 52 weeks. In intent-to-treat analyses at 26 weeks, the percentage of participants with clinically meaningful improvement on the RDQ was higher for those who received MBSR (60.5%) and CBT (57.7%) than for usual care (44.1%) (overall P = .04; relative risk [RR] for MBSR vs usual care, 1.37 [95% CI, 1.06-1.77]; RR for MBSR vs CBT, 0.95 [95% CI, 0.77-1.18]; and RR for CBT vs usual care, 1.31 [95% CI, 1.01-1.69]). The percentage of participants with clinically meaningful improvement in pain bothersomeness at 26 weeks was 43.6% in the MBSR group and 44.9% in the CBT group, vs 26.6% in the usual care group (overall P = .01; RR for MBSR vs usual care, 1.64 [95% CI, 1.15-2.34]; RR for MBSR vs CBT, 1.03 [95% CI, 0.78-1.36]; and RR for CBT vs usual care, 1.69 [95% CI, 1.18-2.41]). Findings for MBSR persisted with little change at 52 weeks for both primary outcomes. CONCLUSIONS AND RELEVANCE: Among adults with chronic low back pain, treatment with MBSR or CBT, compared with usual care, resulted in greater improvement in back pain and functional limitations at 26 weeks, with no significant differences in outcomes between MBSR and CBT. These findings suggest that MBSR may be an effective treatment option for patients with chronic low back pain. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT01467843.
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“However, these effects do not seem to be maintained in the long term [32,42].”
From Prevention of non-specific back pain through exercise and education: A systematic review and meta-analysis (2024) · cites this paper as [32]
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“The disability variable also showed a strong effect in the meta-analysis [28,29,30,31,32,33,36,37,39,40,41,43].”
From Prevention of non-specific back pain through exercise and education: A systematic review and meta-analysis (2024) · cites this paper as [32]
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“One article had a high drop-out rate (61% adherence) (Cherkin et al., 2016)”
From What works in mindfulness interventions for medically unexplained symptoms? A systematic review (2020) · cites this paper as Cherkin et al., 2016
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
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“Mindfulness-based interventions (MBIs) such as mindfulness-based stress reduction (MBSR) 1 and mindfulness-based cognitive therapy (MBCT) 2 are efficacious for improving patient-reported outcomes such as pain interference, pain intensity, and psychological distress for people living with chronic pain.3–5”
From Are Formal and Informal Home Mindfulness Practice Quantities Associated With Outcomes? Results From a Pilot Study of a Four-Week Mindfulness Intervention for Chronic Pain Management. (2024) · cites this paper as [3]
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“Attendance averaged ∼75%, or three out of four sessions, which is within the range of 5.5 to 7.6 sessions attended (out of eight) found in previous studies of MBIs for chronic pain [19, 47–49].”
From Feasibility and Acceptability of an Abbreviated, Four-Week Mindfulness Program for Chronic Pain Management. (2020) · cites this paper as [19]
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“In the Mind-body Approaches to Pain (MAP) randomized controlled trial (RCT), we found both CBT and mindfulness-based stress reduction (MBSR) to have benefits for pain and function among individuals with chronic low back pain (CLBP).13”
The cited source says what the claim attributes to it.
In the citing paper
“Both mindfulness-based stress reduction (MBSR) and cognitive-behavioral therapy (CBT) are effective for chronic low back pain (CLBP)”
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In the citing paper
“and retreat attendance rate (26% of participants randomized to MBSR),13”
From Moderators and Nonspecific Predictors of Treatment Benefits in a Randomized Trial of Mindfulness-Based Stress Reduction vs Cognitive-Behavioral Therapy vs Usual Care for Chronic Low Back Pain (2023) · cites this paper as [13]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
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“These results suggest that the finding in the MAP RCT of CBT having greater benefit than MBSR for depression post-treatment13 may have been due largely to treatment differences among those who were more depressed.”
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In the citing paper
“session attendance rates (56.6% and 50.9% of randomized participants attended at least 6 sessions of CBT and MBSR, respectively)”
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In the citing paper
“research demonstrating that MM can lead to reductions in pain intensity,[16] pain interference,[15, 29] and pain-related affect,[30, 31]”
From The chronic pain skills study: Protocol for a randomized controlled trial comparing hypnosis, mindfulness meditation and pain education in Veterans (2020) · cites this paper as [15]
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“Two self-management approaches, hypnosis (HYP)[12–14] and mindfulness meditation(MM)[15–17], show promise across a range of chronic pain conditions and have been identified as priorities for further study and dissemination.[18]”
From The chronic pain skills study: Protocol for a randomized controlled trial comparing hypnosis, mindfulness meditation and pain education in Veterans (2020) · cites this paper as [15]
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In the citing paper
“Relevant trials have suggested that MBSR may be an effective treatment option for patients with chronic low back pain [14–16].”
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In the citing paper
“The combination of exercise therapy and health education has a strong effect on the pain variable compared to exercise therapy alone or health education alone [31,32,33,34,35,36,37,38,39,40,43].”
From Prevention of non-specific back pain through exercise and education: A systematic review and meta-analysis (2024) · cites this paper as [32]
Experimental — accuracy not yet measuredIn the citing paper
“By contrast, in a seminal study, Cherkin et al.19 found that both MBSR and CBT significantly improved ratings of functional limitations, pain-related distress, and pain intensity in chronic lower back pain patients when compared with standard of care.”
From The neural mechanisms of mindfulness-based pain relief: a functional magnetic resonance imaging-based review and primer (2019) · cites this paper as [19]
In the citing paper
“In the same study, findings persisted for MBSR and CBT at 8-, 26-, and 52-week follow-up, demonstrating the durability of mindfulness on certain pain-related outcomes over time.”
From The neural mechanisms of mindfulness-based pain relief: a functional magnetic resonance imaging-based review and primer (2019) · cites this paper as [19]
In the citing paper
“There is reliable and growing evidence demonstrating that long-term mindfulness practice can lead to significant increases in pain threshold values and lower pain sensitivity even when participants are not explicitly practicing mindfulness.13,19,43,46,82,83”
From The neural mechanisms of mindfulness-based pain relief: a functional magnetic resonance imaging-based review and primer (2019) · cites this paper as [19]
In the citing paper
“The MBSR and CBT programs were found to be significantly more effective at reducing pain intensity and reports of pain being bothersome when compared to usual care after 8, 26, and 52 weeks.71”
From Mindfulness meditation-based pain relief: a mechanistic account (2016) · cites this paper as [71]
In the citing paper
“While there were no significant differences between the CBT and MBSR programs in pain-related outcomes”
From Mindfulness meditation-based pain relief: a mechanistic account (2016) · cites this paper as [71]
In the citing paper
“In recent years, MBI has been successfully implemented to improve psychological health and coping skills 8 in a range of clinical populations, including chronic disease 9 , pain disorders 10 and cancer 11 .”
From Effects of mindfulness-based intervention on glycemic control and psychological outcomes in people with diabetes: a systematic review and meta-analysis (2021) · cites this paper as [10]
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Kligler, B., Bair, M. J., Banerjea, R., DeBar, L., Ezeji-Okoye, S., Lisi, A., Murphy, J. L., Sandbrink, F., & Cherkin, D. C. (2018) · Journal of General Internal Medicine · doi:10.1007/s11606-018-4323-z · Cited by 95
Self-citationManaging Chronic Pain in Primary Care: It Really Does Take a Village
Seal, K. H., Becker, W. C., Tighe, J., Li, Y., & Rife, T. (2017) · Journal of General Internal Medicine · doi:10.1007/s11606-017-4047-5 · Cited by 96
Upchurch, D. M., & Johnson, P. J. (2018) · Journal of Women s Health · doi:10.1089/jwh.2018.7178 · Cited by 93
Day, M. A., Ward, L. C., Ehde, D. M., Thorn, B. E., Burns, J., Barnier, A., Mattingley, J. B., & Jensen, M. P. (2019) · Pain Medicine · doi:10.1093/pm/pny273 · Cited by 91
Wardhan, R., & Chelly, J. E. (2017) · F1000Research · doi:10.12688/f1000research.12286.1 · Cited by 91
Brotto, L. A., Bergeron, S., Zdaniuk, B., Driscoll, M., Grabovac, A., Sadownik, L. A., Smith, K. B., & Basson, R. (2019) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2019.04.002 · Cited by 87
“Mindfulness led to significantly greater reductions in pain catastrophizing and stress-related affect compared with CBT in patients with rheumatoid arthritis,(23) but similar improvements in disability symptoms and pain bothersomeness in patients with chronic low back pain.(24) Given that women with PVD have premorbid…”
ResultYoga for Military Veterans with Chronic Low Back Pain: A Randomized Clinical Trial
Groessl, E. J., Liu, L., Chang, D. G., Wetherell, J. L., Bormann, J. E., Atkinson, J. H., Baxi, S. C., & Schmalzl, L. (2017) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2017.05.019 · Cited by 97
“In the current study, both groups showed reductions in RMDQ scores at the 6-week and 12-week time points, which is not unexpected with comparison groups receiving placebo or usual care in cLBP trials.(35,47) However, the initial improvement in RMDQ scores among DT participants was not reflected in the painintensity sc…”
MethodResultHerman, P. M., Anderson, M. L., Sherman, K. J., Balderson, B. H. K., Turner, J. A., & Cherkin, D. C. (2017) · Spine · doi:10.1097/brs.0000000000002344 · Cited by 92
“Details on the design of the trial, including its interventions and outcomes were previously published.(6,10) The trial compared the effectiveness of two mind-body interventions (MBSR and CBT) to UC in individuals with chronic (>3 months) nonspecific low back pain.”
Self-citationPrimary Care of Patients With Chronic Pain
Schneiderhan, J. R., Clauw, D. J., & Schwenk, T. L. (2017) · JAMA · doi:10.1001/jama.2017.5787 · Cited by 87
Mindfulness Meditation for Fibromyalgia: Mechanistic and Clinical Considerations
Adler-Neal, A. L., & Zeidan, F. Z. (2017) · Current Rheumatology Reports · doi:10.1007/s11926-017-0686-0 · Cited by 101
Gascón, E. M. P., Narambuena, L., Leal‐Costa, C., & Román, C. J. V.-D. H. (2020) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2020.08.001 · Cited by 85
Chronic Pain and Sleep Disorders in Primary Care
Jank, R., Gallee, A., Boeckle, M., Fiegl, S., & Pieh, C. (2017) · Pain Research and Treatment · doi:10.1155/2017/9081802 · Cited by 83
Cherkin, D. C., Anderson, M. L., Sherman, K. J., Balderson, B. H. K., Cook, A. J., Hansen, K. E., & Turner, J. A. (2017) · JAMA · doi:10.1001/jama.2016.17814 · Cited by 79
Self-citationAn update on non-pharmacological interventions for pain relief
Wang, Y., Aaron, R. V., Attal, N., & Colloca, L. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.101940 · Cited by 109
Complementary and Integrated Health Approaches: What Do Veterans Use and Want
Taylor, S. L., Hoggatt, K. J., & Kligler, B. (2019) · Journal of General Internal Medicine · doi:10.1007/s11606-019-04862-6 · Cited by 77
Ali, A., Weiss, T. R., Dutton, A., McKee, D., Jones, K. D., Kashikar-Zuck, S., Silverman, W. K., & Shapiro, E. D. (2017) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2016.12.053 · Cited by 75
Jensen, M. P., Mendoza, M. E., Ehde, D. M., Patterson, D. R., Molton, I. R., Dillworth, T. M., Gertz, K. J., Chan, J., Hakimian, S., Battalio, S. L., et al. (2020) · Pain · doi:10.1097/j.pain.0000000000001943 · Cited by 75
“However, researchers tend to most often evaluate the efficacy of 6 to 10 psychological pain treatments sessions, with 8 sessions being the most common.(5,16,36,42,80,82,87,92) Here, we chose to evaluate the efficacy of 4 sessions of treatment.”
BackgroundResultLeading the Way to Solutions to the Opioid Epidemic: AOA Critical Issues
Seymour, R. B., Ring, D., Higgins, T., & Hsu, J. R. (2017) · Journal of Bone and Joint Surgery · doi:10.2106/jbjs.17.00066 · Cited by 74
Garland, E. L., Bryan, C. J., Finan, P. H., Thomas, E. A., Priddy, S. E., Riquino, M. R., & Howard, M. O. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.07.033 · Cited by 71
“To date, mindfulness approaches for chronic pain have been shown to be efficacious but not superior to traditional CBT in well-controlled trials (Cherkin et al., 2016) and meta-analyses (Veehof et al., 2011).”
BackgroundA Pilot Mobile-Based Mindfulness Intervention for Cancer Patients and Their Informal Caregivers
Kubo, A., Altschuler, A., Kurtovich, E., Hendlish, S., Laurent, C. A., Kolevska, T., Li, Y., & Avins, A. (2018) · Mindfulness · doi:10.1007/s12671-018-0931-2 · Cited by 73
Henriksson, J., Wasara, E., & Rönnlund, M. (2016) · Psychological Reports · doi:10.1177/0033294116675086 · Cited by 73
“Support of the effectiveness of a MBI for pain was provided in a subsequent study by Cherkin et al. (2016).”
BackgroundNeurophysiological Mechanisms Supporting Mindfulness Meditation–Based Pain Relief: an Updated Review
Jinich-Diamant, A., Garland, E., Baumgartner, J., Gonzalez, N., Riegner, G., Birenbaum, J., Case, L., & Zeidan, F. (2020) · Current Pain and Headache Reports · doi:10.1007/s11916-020-00890-8 · Cited by 69
Petrucci, G., Papalia, G. F., Russo, F., Vadalà, G., Piredda, M., Marinis, M. G. D., Papalia, R., & Denaro, V. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19010060 · Cited by 72
“Study Intervention (s) Control Follow-Up Outcomes (Tool) Conclusion Cherkin et al., 2016 Mindfulness: body scan, yoga, meditation, for 8 weeks.”
BackgroundMethodInfluentialPain Catastrophizing: How Far Have We Come
Simić, K., Savic, B., & Knežević, N. N. (2024) · Neurology International · doi:10.3390/neurolint16030036 · Cited by 78
Baer, R., Gu, J., Cavanagh, K., & Strauss, C. (2019) · Psychological Assessment · doi:10.1037/pas0000744 · Cited by 66
The Role of Heart Rate Variability in Mindfulness-Based Pain Relief
Adler-Neal, A. L., Waugh, C. E., Garland, E. L., Shaltout, H. A., Diz, D. I., & Zeidan, F. Z. (2019) · Journal of Pain · doi:10.1016/j.jpain.2019.07.003 · Cited by 73
“Mindfulness and CBT produce similar pain relieving effects and both techniques likely employ executive control processes to reduce pain, although CBT is premised on changing thoughts about pain, whereas mindfulness is based on accepting thoughts about pain.(19,43,53,57) Importantly, there were no significant differenc…”
BackgroundYoshida, K., Takeda, K., Kasai, T., Makinae, S., Murakami, Y., Hasegawa, A., & Sakai, S. (2020) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsaa020 · Cited by 71
“, 2014), low-back pain (Cherkin et al., 2016) and residual symptoms in depression (Rubia, 2009; Chiesa and Serretti, 2011).”
BackgroundHarrison, R., Zeidan, F., Kitsaras, G., Ozcelik, D., & Salomons, T. V. (2019) · The Journal of Pain · doi:10.1016/j.jpain.2018.10.011 · Cited by 67
Goldberg, S. B., Riordan, K. M., Sun, S., Kearney, D. J., & Simpson, T. L. (2020) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2020.110232 · Cited by 69
The Global Spine Care Initiative: model of care and implementation
Johnson, C. D., Haldeman, S., Chou, R., Nordin, M. C., Green, B. N., Côté, P., Hurwitz, E. L., Kopansky-Giles, D. R., Acaroglu, E. R., Cedraschi, C., et al. (2018) · European Spine Journal · doi:10.1007/s00586-018-5720-z · Cited by 70
Intervenciones psicológicas basadas en mindfulness y sus beneficios: estado actual de la cuestión
Hervás, G., Cebolla, A., & Soler, J. (2016) · Clínica y Salud · doi:10.1016/j.clysa.2016.09.002 · Cited by 67
Mindfulness, mindful consumption, and life satisfaction
Gupta, S., & Verma, H. V. (2019) · Journal of Applied Research in Higher Education · doi:10.1108/jarhe-11-2018-0235 · Cited by 72
Sverre, K. T., Nissen, E. R., Farver-Vestergaard, I., Johannsen, M., & Zachariae, R. H. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2022.102234 · Cited by 79
Myofascial pain – A major player in musculoskeletal pain
Lam, C. M., Francio, V. T., Gustafson, K., Carroll, M. K., York, A., & Chadwick, A. L. (2024) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2024.101944 · Cited by 75
Darnall, B. D., & Colloca, L. (2018) · International review of neurobiology · doi:10.1016/bs.irn.2018.07.022 · Cited by 70
Evaluation Challenges for the Application of Extended Reality Devices in Medicine
Beams, R., Brown, E., Cheng, W., Joyner, J. S., Kim, A. S., Kontson, K. L., Amiras, D., Baeuerle, T., Greenleaf, W., Grossmann, R. J., et al. (2022) · Journal of Imaging Informatics in Medicine · doi:10.1007/s10278-022-00622-x · Cited by 62
“In addition, novel clinical applications provide engaging environments and training for pain management [5, 6] and psychotherapy [7], and the gamification of physical therapy can be employed to increase patient compliance [8].”
BackgroundNathan, H. J., Poulin, P., Wozny, D., Taljaard, M., Smyth, C., Gilron, I., Sorisky, A., Lochnan, H., & Shergill, Y. (2017) · Clinical Diabetes · doi:10.2337/cd17-0077 · Cited by 61
“(33), however, showed no such differences between CBT and MBSR for chronic back pain.”
BackgroundBiobehavioral Mechanisms of Mindfulness as a Treatment for Chronic Stress: An RDoC Perspective
Garland, E. L., Hanley, A. W., Baker, A. K., & Howard, M. O. (2017) · Chronic Stress · doi:10.1177/2470547017711912 · Cited by 65
“Indeed, laboratory-based studies have shown that MBIs can reduce pain sensitivity(107,108) and pain intensity(109,110) during standardized, experimental acute pain inductions, whereas clinical trials indicate that MBIs can reduce chronic pain severity.(67,111) With regard to nonpainful aversive stimuli, participation…”
BackgroundBurns, J. W., Jensen, M. P., Thorn, B., Lillis, T. A., Carmody, J., Newman, A. K., & Keefe, F. (2022) · Pain · doi:10.1097/j.pain.0000000000002357 · Cited by 58
Behavioral therapy approaches for the management of low back pain: an up-to-date systematic review
Vitoula, K., Venneri, A., Varrassi, G., Paladini, A., Sykioti, P., Adewusi, J., & Zis, P. (2018) · Pain and Therapy · doi:10.1007/s40122-018-0099-4 · Cited by 60
“Supplementary therapy with MBSR rather than usual care alone can result in greater improvement in back pain and functional limitations [15, 23].”
BackgroundMusic as an Adjunct to Opioid-Based Analgesia
Chai, P. R., Carreiro, S., Ranney, M. L., Karanam, K., Ahtisaari, M., Edwards, R. R., Schreiber, K. L., Ben-Ghaly, L., Erickson, T. B., & Boyer, E. W. (2017) · Journal of Medical Toxicology · doi:10.1007/s13181-017-0621-9 · Cited by 66
“, catastrophizing, depression) while increasing pain acceptance through cognitive behavioral therapy (CBT) or mindfulness (MT) [5, 6].”
BackgroundBecker, W. C., DeBar, L. L., Heapy, A. A., Higgins, D., Krein, S. L., Lisi, A., Makris, U. E., & Allen, K. D. (2018) · Journal of General Internal Medicine · doi:10.1007/s11606-018-4345-6 · Cited by 59
Ni, Y., Ma, L., & Li, J. (2021) · Journal of Diabetes Investigation · doi:10.1111/jdi.13439 · Cited by 59
Ziadni, M. S., Gonzalez-Castro, L., Anderson, S., Krishnamurthy, P., & Darnall, B. D. (2021) · Journal of Medical Internet Research · doi:10.2196/29672 · Cited by 59
“In contrast, behavioral medicine approaches are low risk and have been shown to have low-to-moderate efficacy for a range of chronic pain conditions [5,7,10-12], with cognitive behavioral therapy (CBT)–pain as the established evidence-based treatment for chronic pain [8,9].”
Burrowes, S. A. B., Goloubeva, O. G., Stafford, K. A., McArdle, P. F., Goyal, M., Peterlin, B. L., Haythornthwaite, J. A., & Seminowicz, D. A. (2021) · Pain · doi:10.1097/j.pain.0000000000002372 · Cited by 69
Necessary components of psychological treatment in pain management programs: A Delphi study
Sharpe, L., Jones, E. B., Ashton-James, C. E., Nicholas, M. K., & Refshauge, K. M. (2020) · European Journal of Pain · doi:10.1002/ejp.1561 · Cited by 63
“Differences on secondary outcomes vary with some favouring CBT (Cherkin et al., 2016, 2017; Zautra et al., 2008) and others favouring ACT (Wetherell et al., 2011) or mindfulness (Dowd et al., 2015).”
ResultInfluentialA Retrospective Systematic Review of Diversity Variables in Mindfulness Research, 2000–2016
Eichel, K., Gawande, R., Acabchuk, R. L., Palitsky, R., Chau, S., Pham, A., Cheaito, A., Yam, D., Lipsky, J., Dumais, T., et al. (2021) · Mindfulness · doi:10.1007/s12671-021-01715-4 · Cited by 60
Castellano‐Tejedor, C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19148536 · Cited by 58
Positive affect and chronic pain: a preregistered systematic review and meta-analysis
Ong, A. D., Thoemmes, F. J., Ratner, K., Ghezzi‐Kopel, K., & Reid, M. C. (2020) · Pain · doi:10.1097/j.pain.0000000000001828 · Cited by 60
Recent advances in understanding neuropathic pain: glia, sex differences, and epigenetics
Machelska, H., & Celik, M. Ö. (2016) · F1000Research · doi:10.12688/f1000research.9621.1 · Cited by 54
Newman, A. K., Dyke, B. P. V., Torres, C. A., Baxter, J. W., Eyer, J. C., Kapoor, S., & Thorn, B. E. (2017) · Pain · doi:10.1097/j.pain.0000000000000964 · Cited by 55
“…moderate to moderately severe levels of depression for the average participant.43 In comparison to a lessdisadvantaged population, Cherkin et al. (2016) report average PHQ-8 scores that represent mild depressive symptoms (mean5 5.6, SD 5 4.1),8,44 Grattan et al.27 report a…”
BackgroundInfluentialWestenberg, R. F., Zale, E. L., Heinhuis, T. J., Özkan, S., Nazzal, A., Lee, S.-G., Chen, N. C., & Vranceanu, A.-M. (2018) · Clinical Orthopaedics & Related Research · doi:10.1007/s11999.0000000000000086 · Cited by 52
“6% rate that has been observed in multisession interventions [14, 25] of classic length.”
BackgroundResultInfluentialCurrent Challenges in the Management of Chronic Pelvic Pain in Women: From Bench to Bedside
Siqueira-Campos, V. M., de Deus, M. S. C., Poli‐Neto, O. B., Silva, J. C. R. E., de Deus, J. M., & Conde, D. M. (2022) · International Journal of Women s Health · doi:10.2147/ijwh.s224891 · Cited by 63
Metadata
- Authors
- Cherkin, D. C., Sherman, K. J., Balderson, B. H., Cook, A. J., Anderson, M. L., Hawkes, R. J., Hansen, K. E., & Turner, J. A.
- Affiliations
- Kaiser Permanente Washington Health Research Institute (US)
- University of Washington (US)
- Corresponding author
- Cherkin, Daniel C.
- ORCID
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 2016-03-22
- Volume
- 315
- Issue
- 12
- Pages
- 1240
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- PMC
- PMC4914381
- OpenAlex
- W2304035054
- Cited by
- 729
- References
- 42
- Citations by year
- 2026: 53 · 2025: 71 · 2024: 82 · 2023: 66 · 2022: 72 · 2021: 80 · 2020: 81 · 2019: 65 · 2018: 54 · 2017: 72 · 2016: 31
- FWCI
- 59.82
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health
- National Center for Complementary and Integrative Health (R01AT006226)
- Topics
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
- Keywords
- mindfulness-based stress reduction, cognitive behavioral therapy, chronic low back pain, functional limitations, pain-related disability, mindfulness meditation, yoga, usual care, young and middle-aged adults, treatment effectiveness comparison, integrated health system, pain catastrophizing, pain acceptance, pain-related hopelessness, pain-related helplessness
- MeSH terms
- Adult, Female, Humans, Male, Middle Aged, Stress, Physiological, Stress, Psychological, Washington, Yoga, Cognitive Behavioral Therapy, Treatment Outcome, Low Back Pain, Sample Size, Young Adult, Intention to Treat Analysis, Mindfulness
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