Real-time mobile monitoring of the dynamic associations among motor activity, energy, mood, and sleep in adults with bipolar disorder
Open accessAbstract
Importance: Biologic systems involved in the regulation of motor activity are intricately linked with other homeostatic systems such as sleep, feeding behavior, energy, and mood. Mobile monitoring technology (eg, actigraphy and ecological momentary assessment devices) allows the assessment of these multiple systems in real time. However, most clinical studies of mental disorders that use mobile devices have not focused on the dynamic associations between these systems. Objectives: To examine the directional associations among motor activity, energy, mood, and sleep using mobile monitoring in a community-identified sample, and to evaluate whether these within-day associations differ between people with a history of bipolar or other mood disorders and controls without mood disorders. Design, Setting, and Participants: This study used a nested case-control design of 242 adults, a subsample of a community-based sample of adults. Probands were recruited by mail from the greater Washington, DC, metropolitan area from January 2005 to June 2013. Enrichment of the sample for mood disorders was provided by volunteers or referrals from the National Institutes of Health Clinical Center or by participants in the National Institute of Mental Health Mood and Anxiety Disorders Program. The inclusion criteria were the ability to speak English, availability to participate, and consent to contact at least 2 living first-degree relatives. Data analysis was performed from June 2013 through July 2018. Main Outcomes and Measures: Motor activity and sleep duration data were obtained from minute-to-minute activity counts from an actigraphy device worn on the nondominant wrist for 2 weeks. Mood and energy levels were assessed by subjective analogue ratings on the ecological momentary assessment (using a personal digital assistant) by participants 4 times per day for 2 weeks. Results: Of the total 242 participants, 92 (38.1%) were men and 150 (61.9%) were women, with a mean (SD) age of 48 (16.9) years. Among the participants, 54 (22.3%) had bipolar disorder (25 with bipolar I; 29 with bipolar II), 91 (37.6%) had major depressive disorder, and 97 (40.1%) were controls with no history of mood disorders. A unidirectional association was found between motor activity and subjective mood level (β = -0.018, P = .04). Bidirectional associations were observed between motor activity (β = 0.176; P = .03) and subjective energy level (β = 0.027; P = .03) as well as between motor activity (β = -0.027; P = .04) and sleep duration (β = -0.154; P = .04). Greater cross-domain reactivity was observed in bipolar disorder across all outcomes, including motor activity, sleep, mood, and energy. Conclusions and Relevance: These findings suggest that interventions focused on motor activity and energy may have greater efficacy than current approaches that target depressed mood; both active and passive tracking of multiple regulatory systems are important in designing therapeutic targets.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis
Gao, W., Emaminejad, S., Nyein, H. Y. Y., Challa, S., Chen, K., Peck, A., Fahad, H. M., Ota, H., Shiraki, H., Kiriya, D., et al. (2016) · Nature · doi:10.1038/nature16521 · Cited by 5,087 · see citing works
Be smart, exercise your heart: Exercise effects on brain and cognition
Hillman, C. H., Erickson, K. I., & Kramer, A. F. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2298 · Cited by 3,563 · see citing works
Transcriptional architecture of the mammalian circadian clock
Takahashi, J. S. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2016.150 · Cited by 2,639 · see citing works
Light Suppresses Melatonin Secretion in Humans
Lewy, A. J., Wehr, T. A., Goodwin, F. K., Newsome, D. A., & Markey, S. P. (1980) · Science · doi:10.1126/science.7434030 · Cited by 1,913 · see citing works
Association of Leisure-Time Physical Activity With Risk of 26 Types of Cancer in 1.44 Million Adults
Moore, S. C., Lee, I.-M., Weiderpass, E., Campbell, P. T., Sampson, J. N., Kitahara, C. M., Keadle, S. K., Arem, H., Berrington de Gonzalez, A., Hartge, P., et al. (2016) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2016.1548 · Cited by 1,487 · see citing works
Kyu, H. H., Bachman, V. F., Alexander, L. T., Mumford, J. E., Afshin, A., Estep, K., Veerman, J. L., Delwiche, K., Iannarone, M. L., Moyer, M. L., et al. (2016) · BMJ · doi:10.1136/bmj.i3857 · Cited by 1,272 · see citing works
Doherty, A., Jackson, D., Hammerla, N., Plötz, T., Olivier, P., Granat, M. H., White, T., van Hees, V. T., Trenell, M. I., Owen, C. G., et al. (2017) · PLOS ONE · doi:10.1371/journal.pone.0169649 · Cited by 1,250 · see citing works
Circadian physiology of metabolism
Panda, S. (2016) · Science · doi:10.1126/science.aah4967 · Cited by 1,092 · see citing works
Light as a central modulator of circadian rhythms, sleep and affect
LeGates, T. A., Fernandez, D. C., & Hattar, S. (2014) · Nature Reviews Neuroscience · doi:10.1038/nrn3743 · Cited by 1,001 · see citing works
Large-scale physical activity data reveal worldwide activity inequality
Althoff, T., Sosič, R., Hicks, J. L., King, A. C., Delp, S. L., & Leskovec, J. (2017) · Nature · doi:10.1038/nature23018 · Cited by 1,000 · see citing works
Vancampfort, D., Firth, J., Schuch, F. B., Rosenbaum, S., Mugisha, J., Hallgren, M., Probst, M., Ward, P. B., Gaughran, F., De Hert, M., et al. (2017) · World Psychiatry · doi:10.1002/wps.20458 · Cited by 957 · see citing works
Mechanisms linking circadian clocks, sleep, and neurodegeneration
Musiek, E. S., & Holtzman, D. M. (2016) · Science · doi:10.1126/science.aah4968 · Cited by 878 · see citing works
Digital Phenotyping: Technology for a New Science of Behavior
Insel, T. R. (2017) · JAMA · doi:10.1001/jama.2017.11295 · Cited by 833 · see citing works
MYERS, J. N., McAuley, P. A., Lavie, C. J., Després, J., Arena, R. A., & Kokkinos, P. F. (2014) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2014.09.011 · Cited by 679 · see citing works
Amount of time spent in sedentary behaviors and cause-specific mortality in US adults
Matthews, C. E., George, S. M., Moore, S. C., Bowles, H. R., Blair, A., Park, Y., Troiano, R. P., Hollenbeck, A., & Schatzkin, A. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.019620 · Cited by 655 · see citing works
The neurobiology, investigation, and treatment of chronic insomnia
Riemann, D. W., Nissen, C., Palagini, L., Otte, A., Perlis, M. L., & Spiegelhalder, K. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00021-6 · Cited by 639 · see citing works
The SBSM Guide to Actigraphy Monitoring: Clinical and Research Applications
Ancoli‐Israel, S., Martin, J. L., BLACKWELL, T. L., Buenaver, L. F., Liu, L., Meltzer, L. J., Sadeh, A., Spira, A. P., & Taylor, D. J. (2015) · Behavioral Sleep Medicine · doi:10.1080/15402002.2015.1046356 · Cited by 561 · see citing works
Ecological momentary assessment of mood disorders and mood dysregulation
Ebner-Priemer, U. W., & Trull, T. J. (2009) · Psychological Assessment · doi:10.1037/a0017075 · Cited by 530 · see citing works
Wu, T., Gao, X., Chen, M., & Van Dam, R. M. (2009) · Obesity Reviews · doi:10.1111/j.1467-789x.2008.00547.x · Cited by 515 · see citing works
O’Donoghue, G., Perchoux, C., Mensah, K., Lakerveld, J., van der Ploeg, H. P., Bernaards, C. M., CHASTIN, S. F. M., Simon, C., O’Gorman, D. J., & Nazare, J. (2016) · BMC Public Health · doi:10.1186/s12889-016-2841-3 · Cited by 492 · see citing works
Coppari, R., Ichinose, M., Lee, C. E., Pullen, A. E., Kenny, C. D., McGovern, R. A., Tang, V., Liu, S. M., Ludwig, T., Chua, S. C., et al. (2005) · Cell Metabolism · doi:10.1016/j.cmet.2004.12.004 · Cited by 457 · see citing works
Physiological adaptations to weight loss and factors favouring weight regain
Greenway, F. L. (2015) · International Journal of Obesity · doi:10.1038/ijo.2015.59 · Cited by 431 · see citing works
Actigraphic assessment of circadian activity and sleep patterns in bipolar disorder
Jones, S. H., Hare, D. J., & Evershed, K. (2005) · Bipolar Disorders · doi:10.1111/j.1399-5618.2005.00187.x · Cited by 323 · see citing works
Sleep and Cardio-Metabolic Disease
Cappuccio, F. P., & Miller, M. A. (2017) · Current Cardiology Reports · doi:10.1007/s11886-017-0916-0 · Cited by 323 · see citing works
Novel melatonin-based therapies: potential advances in the treatment of major depression
Hickie, I. B., & Rogers, N. L. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60095-0 · Cited by 322 · see citing works
Self-citationFacilitated physical activity as a treatment for depressed adults: randomised controlled trial
Chalder, M., Wiles, N., Campbell, J., Hollinghurst, S., Haase, A., Taylor, A. H., Fox, K., Costelloe, C., Searle, A., Baxter, H., et al. (2012) · British medical journal · doi:10.1136/bmj.e2758 · Cited by 264 · see citing works
Activity monitoring in patients with depression: A systematic review
Burton, C., McKinstry, B., Szentagotai Tătar, A., Serrano-Blanco, A., Pagliari, C., & Wolters, M. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2012.07.001 · Cited by 249 · see citing works
A Randomized, Double-Blind, Placebo-Controlled Study of Light Therapy for Antepartum Depression
Wirz-Justice, A., Bader, A., Frisch, U., Stieglitz, R.-D., Alder, J., Bitzer, J., Hösli, I., Jazbec, S., Benedetti, F., Terman, M., et al. (2011) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.10m06188blu · Cited by 241 · see citing works
Light-Intensity Physical Activity and Cardiometabolic Biomarkers in US Adolescents
Carson, V., Ridgers, N. D., Howard, B., WINKLER, E. A. H., Healy, G. N., Owen, N. G., Dunstan, D. W., & Salmon, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071417 · Cited by 221 · see citing works
Feasibility and Validity of Computerized Ecological Momentary Assessment in Schizophrenia
Granholm, E. L., Loh, C., & Swendsen, J. D. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm113 · Cited by 190 · see citing works
Self-citationActivation in Bipolar Disorders
Scott, J. L., Murray, G., Henry, C., Morken, G., Scott, E. M., Angst, J., Merikangas, K. R., & Hickie, I. B. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.3459 · Cited by 187 · see citing works
Self-citationSedentary behavior as a mediator of type 2 diabetes
Hamilton, M. T., Hamilton, D. G., & Zderic, T. W. (2014) · Medicine and Sport Science · doi:10.1159/000357332 · Cited by 185 · see citing works
Sit, D. K., McGowan, J., Wiltrout, C., Diler, R. S., Dills, J. (., Luther, J., Yang, A., Ciolino, J. D., Seltman, H., Wisniewski, S. R., et al. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.16101200 · Cited by 182 · see citing works
Cellini, N., Buman, M. P., McDevitt, E. A., Ricker, A. A., & Mednick, S. C. (2013) · Chronobiology International · doi:10.3109/07420528.2013.782312 · Cited by 181 · see citing works
Arble, D. M., Bass, J., Behn, C. D., Butler, M. P., Challet, E., Czeisler, C., Depner, C. M., Elmquist, J., Franken, P., Grandner, M. A., et al. (2015) · Sleep · doi:10.5665/sleep.5226 · Cited by 173 · see citing works
Circadian Clock and Stress Interactions in the Molecular Biology of Psychiatric Disorders
Landgraf, D., McCarthy, M. J., & Welsh, D. K. (2014) · Current Psychiatry Reports · doi:10.1007/s11920-014-0483-7 · Cited by 170 · see citing works
Hawkins, M., Storti, K. L., Richardson, C. R., King, W. C., Strath, S. J., Holleman, R. G., & Kriska, A. M. (2009) · International Journal of Behavioral Nutrition and Physical Activity · doi:10.1186/1479-5868-6-31 · Cited by 169 · see citing works
Merikangas, K. R., Cui, L., Heaton, L., Nakamura, E., Roca, C., Ding, J., Qin, H., Guo, W., Yao-Shugart, Y., Zarate, C., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.116 · Cited by 166 · see citing works
Self-citationRe-evaluating the effect of age on physical activity over the lifespan
Varma, V. R., Dey, D., Leroux, A., Di, J., Urbanek, J. K., Xiao, L., & Zipunnikov, V. (2017) · Preventive Medicine · doi:10.1016/j.ypmed.2017.05.030 · Cited by 163 · see citing works
Self-citationNorepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish
Singh, C., Oikonomou, G., & Prober, D. A. (2015) · eLife · doi:10.7554/elife.07000 · Cited by 133 · see citing works
Actigraphic features of bipolar disorder: A systematic review and meta-analysis
De Crescenzo, F., Economou, A., Sharpley, A. L., Gormez, A., & Quested, D. J. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.05.003 · Cited by 128 · see citing works
The central circadian timing system
Saper, C. B. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.04.004 · Cited by 123 · see citing works
Johnson, E. I., Grondin, O., Barrault, M., Faytout, M., Helbig, S., Husky, M., Granholm, E. L., Loh, C., Nadeau, L., Wittchen, H., et al. (2009) · International Journal of Methods in Psychiatric Research · doi:10.1002/mpr.276 · Cited by 122 · see citing works
Self-citationGeiger, S. S., Fagundes, C. T., & Siegel, R. M. (2015) · Immunology · doi:10.1111/imm.12525 · Cited by 122 · see citing works
Janney, C. A., Fagiolini, A. M., Swartz, H. A., Jakicic, J. M., Holleman, R. G., & Richardson, C. R. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.09.009 · Cited by 117 · see citing works
Hypothalamic clocks and rhythms in feeding behaviour
Bechtold, D. A., & Loudon, A. S. I. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2012.12.007 · Cited by 114 · see citing works
Bright morning light advances the human circadian system without affecting NREM sleep homeostasis
Dijk, D., Beersma, D. G. M., Daan, S., & Lewy, A. J. (1989) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1989.256.1.r106 · Cited by 113 · see citing works
Actigraphic Assessment of Motor Activity in Acutely Admitted Inpatients with Bipolar Disorder
Krane‐Gartiser, K., Henriksen, T. E. G., Morken, G., Vaaler, A., & Fasmer, O. B. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089574 · Cited by 112 · see citing works
Sleep and metabolism: shared circuits, new connections
Adamantidis, A., & de Lecea, L. (2008) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2008.08.007 · Cited by 111 · see citing works
Genetic Ablation of Hypocretin Neurons Alters Behavioral State Transitions in Zebrafish
Elbaz, I., Yelin‐Bekerman, L., Nicenboim, J., Vatine, G. D., & Appelbaum, L. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1284-12.2012 · Cited by 111 · see citing works
Faedda, G. L., Ohashi, K., Hernandez, M., McGreenery, C. E., Grant, M. C., Baroni, A., Polcari, A., & Teicher, M. H. (2016) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12520 · Cited by 111 · see citing works
Mood reactivity and affective dynamics in mood and anxiety disorders.
Lamers, F., Swendsen, J. D., Cui, L., Husky, M. M., Johns, J., Zipunnikov, V., & Merikangas, K. R. (2018) · Journal of Abnormal Psychology · doi:10.1037/abn0000378 · Cited by 109 · see citing works
Self-citationAj, L., Rl, S., & Singer, C. M. (1985) · PubMed · Cited by 104 · see citing works
Brown, J. A., Woodworth, H. L., & Leinninger, G. M. (2015) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2015.00009 · Cited by 100 · see citing works
Goldstein, T. R., Fersch-Podrat, R. K., Axelson, D., Gilbert, A. M., Hlastala, S. A., Birmaher, B. B., & Frank, E. (2013) · Psychotherapy · doi:10.1037/a0034396 · Cited by 95 · see citing works
Pagani, L., Clair, P. A. S., Teshiba, T. M., Service, S. K., Fears, S. C., Araya, C., Araya, X., Bejarano, J., Ramirez, M., Castrillón, G., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1513525113 · Cited by 88 · see citing works
Exacerbated craving in the presence of stress and drug cues in drug-dependent patients
Preston, K. L., Kowalczyk, W. J., Phillips, K. A., Jobes, M. L., Vahabzadeh, M., Lin, J.-L., Mezghanni, M., & Epstein, D. H. (2018) · Neuropsychopharmacology · doi:10.1038/npp.2017.275 · Cited by 84 · see citing works
Circadian clocks: Not your grandfather’s clock
Turek, F. W. (2016) · Science · doi:10.1126/science.aal2613 · Cited by 82 · see citing works
A brief review of exercise, bipolar disorder, and mechanistic pathways
Thomson, D., Turner, A., Lauder, S., Gigler, M. E., Berk, L., Singh, A., Pasco, J. A., Berk, M., & Sylvia, L. G. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.00147 · Cited by 79 · see citing works
Baron, K. G., Reid, K. J., Kim, T., Horn, L. V., Attarian, H. P., Wolfe, L. F., Siddique, J., Santostasi, G., & Zee, P. C. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.194 · Cited by 79 · see citing works
Treating DSM-IV Depression With Atypical Features
Stewart, J. W., & Thase, M. E. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.0407e10 · Cited by 69 · see citing works
Chronotype predicts positive affect rhythms measured by ecological momentary assessment
Miller, M. A., Rothenberger, S. D., Hasler, B. P., Donofry, S. D., Wong, P. M., Manuck, S. B., Kamarck, T. W., & Roecklein, K. A. (2015) · Chronobiology International · doi:10.3109/07420528.2014.983602 · Cited by 67 · see citing works
Ekelund, U., Kolle, E., Steene‐Johannessen, J., Dalene, K. E., Nilsen, A. K. O., Anderssen, S. A., & Hansen, B. H. (2017) · International Journal of Obesity · doi:10.1038/ijo.2017.186 · Cited by 66 · see citing works
Swendsen, J. D. (1997) · Cognitive Therapy and Research · doi:10.1023/a:1021872410824 · Cited by 63 · see citing works
Self-citationComputerized ambulatory monitoring in mood disorders: Feasibility, compliance, and reactivity
Husky, M. M., Gindre, C., Mazure, C. M., Brebant, C., Nolen-Hoeksema, S., Sanacora, G., & Swendsen, J. (2010) · Psychiatry Research · doi:10.1016/j.psychres.2010.04.045 · Cited by 62 · see citing works
Self-citationComparability of Measured Acceleration from Accelerometry-Based Activity Monitors
Rowlands, A. V., Fraysse, F., Catt, M., Stiles, V. H., Stanley, R. M., Eston, R. G., & Olds, T. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000394 · Cited by 61 · see citing works
Methodology and Reporting of Mobile Health and Smartphone Application Studies for Schizophrenia
Torous, J. B., Firth, J., Mueller, N. E., Onnela, J.-P. “., & Baker, J. T. (2017) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000133 · Cited by 59 · see citing works
Kim, J., Nakamura, T., Kikuchi, H., Sasaki, T., & Yamamoto, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0074979 · Cited by 58 · see citing works
Carr, O., Saunders, K. E. A., Tsanas, A., Bilderbeck, A. C., Palmius, N., Geddes, J. R., Foster, R., Goodwin, G. M., & De Vos, M. (2018) · Scientific Reports · doi:10.1038/s41598-018-19888-9 · Cited by 57 · see citing works
Shou, H., Cui, L., Hickie, I., Lameira, D., Lamers, F., Zhang, J., Crainiceanu, C., Zipunnikov, V, & Merikangas, K. R. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.136 · Cited by 53 · see citing works
Self-citationInfluence of light exposure during early life on the age of onset of bipolar disorder
Bauer, M., Glenn, T., Alda, M., Andreassen, O. A., Angelopoulos, E. K., Ardau, R., Baethge, C., Bauer, R., Baune, B. T., Bellivier, F., et al. (2015) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2015.03.013 · Cited by 50 · see citing works
Vancampfort, D., Stubbs, B., Herring, M. P., Hallgren, M. Å., & Koyanagi, A. (2017) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2017.09.006 · Cited by 50 · see citing works
Swendsen, J. D. (1998) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.74.5.1398 · Cited by 47 · see citing works
Self-citationKräuchi, K., Wirz‐Justice, A., & Graw, P. (1993) · Psychiatry Research · doi:10.1016/0165-1781(93)90013-7 · Cited by 44 · see citing works
Urbanek, J. K., Spira, A. P., Di, J., Leroux, A., Crainiceanu, C., & Zipunnikov, V. (2017) · Chronobiology International · doi:10.1080/07420528.2017.1411359 · Cited by 43 · see citing works
Self-citationYerrakalva, D., Cooper, A., Westgate, K. L., Khaw, K., Wareham, N. J., Brage, S., Griffin, S. J., & Wijndaele, K. (2017) · International Journal of Epidemiology · doi:10.1093/ije/dyx123 · Cited by 30 · see citing works
Light Therapy for Depression: Present Status, Problems, and Perspectives
Wirz‐Justice, A. (2010) · Psychopathology · doi:10.1159/000285145 · Cited by 29 · see citing works
Assessing sleep quality using self‐report and actigraphy in PTSD
Slightam, C. A., Petrowski, K., Jamison, A. L., Keller, M., Bertram, F., Kim, S. Y., & Roth, W. T. (2017) · Journal of Sleep Research · doi:10.1111/jsr.12632 · Cited by 27 · see citing works
Johns, J., Di, J., Merikangas, K. R., Cui, L., Swendsen, J. D., & Zipunnikov, V. (2019) · Psychological Assessment · doi:10.1037/pas0000661 · Cited by 22 · see citing works
Self-citationSleep Assessment in Large Cohort Studies with High-Resolution Accelerometers
Zinkhan, M., & Kantelhardt, J. W. (2016) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2016.08.006 · Cited by 21 · see citing works
Frank, E., Benabou, M., Bentzley, B. S., Bianchi, M. T., Goldstein, T. R., Konopka, G., Maywood, E. S., Pritchett, D., Sheaves, B., & Thomas, J. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12600 · Cited by 20 · see citing works
Johnson, S. L., Gershon, A., & Starov, V. (2015) · Psychiatry Research · doi:10.1016/j.psychres.2015.06.016 · Cited by 13 · see citing works
Measuring Physical Activity and Sedentary Behavior in Youth with Type 2 Diabetes
Rockette‐Wagner, B., Storti, K. L., Edelstein, S. L., Delahanty, L. M., Galvin, B., Jackson, A., & Kriska, A. M. (2016) · Childhood Obesity · doi:10.1089/chi.2015.0151 · Cited by 12 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Mobile Apps for Mental Health Issues: Meta-Review of Meta-Analyses
Lecomte, T., Potvin, S., Corbière, M., Guay, S., Samson, C., Cloutier, B., Francoeur, A., Pennou, A., & Khazaal, Y. (2020) · JMIR mHealth and uHealth · doi:10.2196/17458 · Cited by 336 · see citing works
Circadian rhythms and disorders of the timing of sleep
Meyer, N., Harvey, A. G., Lockley, S. W., & Dijk, D.-J. (2022) · The Lancet · doi:10.1016/s0140-6736(22)00877-7 · Cited by 346 · see citing works
Transdiagnostic clinical staging in youth mental health: a first international consensus statement
Shah, J. L., Scott, J., McGorry, P. D., Cross, S. P. M., Keshavan, M. S., Nelson, B., Wood, S. J., Marwaha, S., Yung, A. R., Scott, E. M., et al. (2020) · World Psychiatry · doi:10.1002/wps.20745 · Cited by 291 · see citing works
Self-citationHickie, I. B., Scott, E. M., Cross, S. P., Iorfino, F., Davenport, T. A., Guastella, A. J., Naismith, S. L., Carpenter, J. S., Rohleder, C., Crouse, J. J., et al. (2019) · Medical Journal of Australia · doi:10.5694/mja2.50383 · Cited by 208 · see citing works
Self-citationIorfino, F., Scott, E. M., Carpenter, J. S., Cross, S. P., Hermens, D. F., Killedar, M., Nichles, A., Zmicerevska, N., White, D., Guastella, A. J., et al. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.2360 · Cited by 188 · see citing works
Self-citationMcIntyre, R. S., Alda, M., Baldessarini, R. J., Bauer, M., Berk, M., Correll, C. U., Fagiolini, A., Fountoulakis, K., Frye, M. A., Grunze, H., et al. (2022) · World Psychiatry · doi:10.1002/wps.20997 · Cited by 171 · see citing works
Personalized machine learning of depressed mood using wearables
Shah, R. V., Grennan, G., Zafar-Khan, M., Alim, F., Dey, S., Ramanathan, D., & Mishra, J. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01445-0 · Cited by 123 · see citing works
Kim, H., Lee, S., Lee, S., Hong, S., Kang, H., & Kim, N. (2019) · JMIR mHealth and uHealth · doi:10.2196/14149 · Cited by 131 · see citing works
Circadian depression: A mood disorder phenotype
Carpenter, J. S., Crouse, J. J., Scott, E. M., Naismith, S. L., Wilson, C., Scott, J., Merikangas, K. R., & Hickie, I. B. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.045 · Cited by 114 · see citing works
Self-citationZheng, Y., Wang, W., Zhong, Y., Wu, F., Zhu, Z., Tham, Y.-C., Lamoureux, E., Xiao, L., Zhu, E., Liu, H., et al. (2021) · Journal of Medical Internet Research · doi:10.2196/24316 · Cited by 73 · see citing works
Domschke, K., Seuling, P. D., Schiele, M. A., Bandelow, B., Batelaan, N. M., Bokma, W. A., Branchi, I., Broich, K., Burkauskas, J., Davies, S. J. C., et al. (2024) · World Psychiatry · doi:10.1002/wps.21177 · Cited by 46 · see citing works
Sun, H., Gao, X., Que, X., Liu, L., Ma, J., He, S., Gao, Q., & Wang, T. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.11.034 · Cited by 33 · see citing works
Personalized Machine Learning-Based Prediction of Wellbeing and Empathy in Healthcare Professionals
Nan, J., Herbert, M. S., Purpura, S., Henneken, A. N., Ramanathan, D., & Mishra, J. (2024) · Sensors · doi:10.3390/s24082640 · Cited by 22 · see citing works
Towards Personalised Mood Prediction and Explanation for Depression from Biophysical Data
Chatterjee, S., Mishra, J., Sundram, F., & Roop, P. (2023) · Sensors · doi:10.3390/s24010164 · Cited by 15 · see citing works
Motor actions across psychiatric disorders: a research domain criteria (RDoC) perspective
Osborne, K. J., Walther, S., & Mittal, V. A. (2024) · Clinical Psychology Review · doi:10.1016/j.cpr.2024.102511 · Cited by 9 · see citing works
Similarity-based multimodal regression
Chen, A. A., Weinstein, S. M., Adebimpe, A., Gur, R. C., Gur, R. E., Merikangas, K. R., Satterthwaite, T. D., Shinohara, R. T., & Shou, H. (2024) · Biostatistics · doi:10.1093/biostatistics/kxad033 · Cited by 6 · see citing works
Self-citationNan, J., Purpura, S., Jaiswal, S., Afshar, H., Maric, V., Manchanda, J. K., Taylor, C. T., Ramanathan, D., & Mishra, J. (2026) · NPP—Digital Psychiatry and Neuroscience · doi:10.1038/s44277-026-00062-3 · Cited by 1 · see citing works
“The app sent regular noti fi cations daily to all participants following the methodology of recent research on longitudinal mood monitoring [17, 18, 44].”
- Authors
- Merikangas, K. R., Swendsen, J., Hickie, I. B., Cui, L., Shou, H., Merikangas, A. K., Zhang, J., Lamers, F., Crainiceanu, C., Volkow, N. D., & Zipunnikov, V.
- Affiliations
- National Institute of Mental Health (US)
- Université de Bordeaux (FR)
- The University of Sydney (AU)
- University of Pennsylvania (US)
- Children's Hospital of Philadelphia (US)
- Chinese University of Hong Kong (HK)
- Amsterdam Public Health (NL)
- Johns Hopkins University (US)
- National Institute on Drug Abuse (US)
- Corresponding author
- Merikangas, Kathleen Ries
- ORCID
- Venue
- JAMA Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2019-02-01
- Volume
- 76
- Issue
- 2
- Pages
- 190
- ISSN
- 2168-622X (ISSN-L)
- PMC
- PMC6439734
- OpenAlex
- W2903886448
- Cited by
- 231
- References
- 83
- Citations by year
- 2026: 23 · 2025: 34 · 2024: 27 · 2023: 21 · 2022: 39 · 2021: 25 · 2020: 32 · 2019: 30
- FWCI
- 17.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- JAMA Psychiatry (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (submittedVersion, other-oa)
- HAL (submittedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute (R01HL123407, R01HL130483)
- National Institute of Mental Health
- National Institute of Neurological Disorders and Stroke (R01NS060910)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- bipolar disorder, motor activity, sleep duration, energy levels, mood, actigraphy, ecological momentary assessment, mobile monitoring, bidirectional relationship, major depressive disorder, homeostatic systems, mood disorders, sleep homeostasis, feeding behavior, energy homeostasis, real-time monitoring, community sample, first-degree relatives
- MeSH terms
- Ecological Momentary Assessment, Adult, Affect, Bipolar Disorder, Female, Humans, Male, Middle Aged, Motor Activity, Sleep, Case-Control Studies, Monitoring, Ambulatory, Computers, Handheld, Actigraphy, Self Report
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
