Cited by 559Advanced Sensor and Energy Harvesting MaterialsNon-Invasive Vital Sign MonitoringNeuroscience and Neural Engineering

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Wearable and Implantable Devices for Cardiovascular Healthcare: from Monitoring to Therapy Based on Flexible and Stretchable Electronics

Hong, Yongseok Joseph, Jeong, Hyoyoung, Cho, Kyoung Won, Lu, Nanshu, Kim, Dae‐Hyeong·2019·Advanced Functional Materials

DOI 10.1002/adfm.201808247

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Abstract

Cardiovascular disease is the leading cause of death and has dramatically increased in recent years. Continuous cardiac monitoring is particularly important for early diagnosis and prevention, and flexible and stretchable electronic devices have emerged as effective tools for this purpose. Their thin, soft, and deformable features allow intimate and long‐term integration with biotissues, which enables continuous, high‐fidelity, and sometimes large‐area cardiac monitoring on the skin and/or heart surface. In addition to monitoring, intimate contact is also crucial for high‐precision therapies. Combined with tissue engineering, soft bioelectronics have also demonstrated the capability to repair damaged cardiac tissues. This review highlights the recent advances in wearable and implantable devices based on flexible and stretchable electronics for cardiovascular monitoring and therapy. First, wearable/implantable soft bioelectronics for cardiovascular monitoring (e.g., the electrocardiogram, blood pressure, and oxygen saturation level) are reviewed. Then, advances in cardiovascular therapy based on soft bioelectronics (e.g., mesh pacing, ablation, robotic sleeves, and electronic stents) are discussed. Finally, device‐assisted tissue engineering therapy (e.g., functional electronic scaffolds and in vitro cardiac platforms) is discussed.

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Authors: Hong, Y. J., Jeong, H., Cho, K. W., Lu, N., & Kim, D.
Affiliations: Seoul National University (KR)
The University of Texas at Austin (US)
Corresponding author: Lu, Nanshu
Kim, Dae‐Hyeong
ORCID: Hong, Yongseok Joseph
Jeong, Hyoyoung
Cho, Kyoung Won
Lu, Nanshu
Kim, Dae‐Hyeong
Venue: Advanced Functional Materials
Publisher: Wiley
Published: 2019-02-27
Volume: 29
Issue: 19
ISSN: 1616-301X (ISSN-L)
1616-3028
DOI: 10.1002/adfm.201808247
OpenAlex: W2918664767
Cited by: 559
References: 298
Citations by year: 2026: 35 · 2025: 89 · 2024: 91 · 2023: 95 · 2022: 73 · 2021: 88 · 2020: 66 · 2019: 22
FWCI: 21.92
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#am (am, 365 d)
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Advanced Functional Materials (publishedVersion)
Seoul National University Open Repository (Seoul National University) (submittedVersion)
Funders: Office of Naval Research (N00014‐16‐1‐2044)
National Research Foundation of Korea
Topics: Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
Keywords: wearable devices, biomedical implants, flexible electronics, stretchable electronics, soft bioelectronics, cardiovascular monitoring, cardiac pacing, cardiac ablation, tissue engineering, in vitro cardiac models, electrocardiogram, blood pressure monitoring, oxygen saturation monitoring, cardiac repair

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Wearable and Implantable Devices for Cardiovascular Healthcare: from Monitoring to Therapy Based on Flexible and Stretchable Electronics

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