Wearable and implantable devices for drug delivery: Applications and challenges
Abstract
Poor adherence to drug dosing schedule is responsible for ∼50% of hospitalization cases. Most patients fail to adhere to a strict dosing schedule due to invasive drug administration, off-target toxicities, or medical conditions like dementia. The emerging concept of wearable devices (WDs), implantable devices (IDs) and combined wearable and implantable devices (WIDs) for drug delivery has created new opportunities for treating patients with chronic diseases needing repeated and long-term medical attention like diabetes, ocular disorders, cancer, wound healing, cardiovascular diseases, and contraception. WDs, worn on the body surface have created appealing non-invasive, self-administrable drug delivery platforms which receive huge patient compliance. Microneedle-skin patches, wound healing patches, drug-eluting contact lenses, mouth guards, intra-vaginal rings, pharmaceutical jewelry, and drug-loaded self-care textiles are popular WDs explored in drug delivery. In contrast, IDs are surgically placed inside body tissue allowing higher payload and enhanced localized effect for an extended duration. Hormone micropumps, hydrogel/nanofibrous depot, coronary stents, intravitreal devices, and intrauterine devices are some representative examples of IDs. In this review, we have described the past 10 years of research progress on drug-delivering WDs and IDs in the context of treating diseases that demand repeated and long-term medication, especially those affecting soft tissues. We highlighted several technical challenges that need to be addressed before considering the translation of such technologies to clinics.
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Wearable delivery devices have been used to deliver a range of therapeutic agents, including polypeptides, polysaccharides, small molecules, and growth factors, continuously and responsively.
“These devices have been used to deliver a range of therapeutic agents, including polypeptides, polysaccharides, small molecules, and growth factors, continuously and responsively (Kar et al. 2022; Yang, Yuan et al. 2022a; Yang, Yuan et al. 2022b).”
From Artificial intelligence enhanced sensors - enabling technologies to next-generation healthcare and biomedical platform (2023) · cites this paper as Kar et al. 2022
Cites
Osterberg, L., & Blaschke, T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050100 · Cited by 7,974 · see citing works
Wearable biosensors for healthcare monitoring
Kim, J., Campbell, A. S., de Ávila, B. E.-F., & Wang, J. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0045-y · Cited by 3,373 · see citing works
On the mechanisms of biocompatibility
Williams, D. F. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.023 · Cited by 2,772 · see citing works
Lee, H., Choi, T. K., Lee, Y. B., Cho, H. R., Ghaffari, R., Wang, L., Choi, H. J., Chung, T. D., Lu, N., Hyeon, T., et al. (2016) · Nature Nanotechnology · doi:10.1038/nnano.2016.38 · Cited by 1,802 · see citing works
Multifunctional wearable devices for diagnosis and therapy of movement disorders
Son, D., Lee, J., Qiao, S., Ghaffari, R., Kim, J., Lee, J. E., Song, C., Kim, S. J., Lee, D. J., Jun, S. W., et al. (2014) · Nature Nanotechnology · doi:10.1038/nnano.2014.38 · Cited by 1,462 · see citing works
Franz, S., Rammelt, S., Scharnweber, D., & Simon, J. C. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.05.078 · Cited by 1,391 · see citing works
Microneedles: A smart approach and increasing potential for transdermal drug delivery system
Waghule, T., Singhvi, G., Dubey, S. K., Pandey, M. M., Gupta, G., Singh, M., & Dua, K. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.10.078 · Cited by 1,277 · see citing works
Lee, H., Song, C., Hong, Y. S., Kim, M., Cho, H. R., Kang, T., Shin, K., Choi, S. H., Hyeon, T., & Kim, D.-H. (2017) · Science Advances · doi:10.1126/sciadv.1601314 · Cited by 1,118 · see citing works
Advanced materials and processing for drug delivery: The past and the future
Zhang, Y., Chan, H. F., & Leong, K. W. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.10.003 · Cited by 1,008 · see citing works
Smart wearable systems: Current status and future challenges
Chan, M., Estève, D., Fourniols, J.-Y., Escriba, C., & Campo, E. (2012) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2012.09.003 · Cited by 953 · see citing works
Nobuyoshi, M., Kimura, T., Nosaka, H., Mioka, S., Ueno, K., 横井, 博., Hamasaki, N., Horiuchi, H., & Ohishi, H. (1988) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(88)80046-9 · Cited by 875 · see citing works
Advances in Biomaterials for Drug Delivery
Fenton, O. S., Olafson, K. N., Pillai, P. S., Mitchell, M. J., & Langer, R. (2018) · Advanced Materials · doi:10.1002/adma.201705328 · Cited by 869 · see citing works
Yu, J., Zhang, Y., Ye, Y., DiSanto, R., Sun, W., Ranson, D., Ligler, F. S., Buse, J. B., & Gu, Z. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1505405112 · Cited by 852 · see citing works
Biocompatibility of engineered nanoparticles for drug delivery
Naahidi, S., Jafari, M., Edalat, F., Raymond, K. P., Khademhosseini, A., & Chen, P. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.12.013 · Cited by 814 · see citing works
Mathematical modeling of bioerodible, polymeric drug delivery systems
Siepmann, J. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00116-8 · Cited by 774 · see citing works
Drug-Eluting Coronary-Artery Stents
Stefanini, G. G., & Holmes, D. R. (2013) · New England Journal of Medicine · doi:10.1056/nejmra1210816 · Cited by 737 · see citing works
Advances in healthcare wearable devices
Iqbal, S. M. A., Mahgoub, I., Du, E., Leavitt, M. A., & Asghar, W. (2021) · npj Flexible Electronics · doi:10.1038/s41528-021-00107-x · Cited by 714 · see citing works
Multifunctional materials for implantable and wearable photonic healthcare devices
Lee, G., Moon, H., Kim, H., Lee, G. H., Kwon, W., Yoo, S., Myung, D. J., Yun, S. H., Bao, Z., & Hahn, S. K. (2020) · Nature Reviews Materials · doi:10.1038/s41578-019-0167-3 · Cited by 673 · see citing works
Evolution of Wearable Devices with Real-Time Disease Monitoring for Personalized Healthcare
Guk, K., Han, G., Lim, J., Jeong, K., Kang, T., Lim, E.-K., & Jung, J. (2019) · Nanomaterials · doi:10.3390/nano9060813 · Cited by 624 · see citing works
Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs
Yu, J., Wang, J., Zhang, Y., Chen, G., Mao, W., Ye, Y., Kahkoska, A. R., Buse, J. B., Langer, R., & Gu, Z. (2020) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0508-y · Cited by 604 · see citing works
Hong, Y. J., Jeong, H., Cho, K. W., Lu, N., & Kim, D. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201808247 · Cited by 559 · see citing works
Drug-Eluting or Bare-Metal Stents for Coronary Artery Disease
Bønaa, K. H., Mannsverk, J., Wiseth, R., Aaberge, L., Myreng, Y., Nygard, O. K., Nilsen, D. W. T., Kløw, N., Uchto, M., Trovik, T. S., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1607991 · Cited by 553 · see citing works
Transdermal Delivery of Drugs with Microneedles—Potential and Challenges
Ita, K. B. (2015) · Pharmaceutics · doi:10.3390/pharmaceutics7030090 · Cited by 527 · see citing works
Three-Year Follow-up after Implantation of Metallic Coronary-Artery Stents
Kimura, T., Yokoi, H., Nakagawa, Y., Tamura, T., Kaburagi, S., Sawada, Y., Sato, Y., 横井, 博., Hamasaki, N., Nosaka, H., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199602293340903 · Cited by 505 · see citing works
Rapidly separable microneedle patch for the sustained release of a contraceptive
Li, W., Terry, R. N., Tang, J., Feng, M. R., Schwendeman, S. P., & Prausnitz, M. R. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0337-4 · Cited by 496 · see citing works
Wireless smart contact lens for diabetic diagnosis and therapy
Keum, D. H., Kim, S.-K., Koo, J., Lee, G.-H., Jeon, C., Mok, J. W., Mun, B. H., Lee, K. J., Kamrani, E., Joo, C.-K., et al. (2020) · Science Advances · doi:10.1126/sciadv.aba3252 · Cited by 483 · see citing works
Smart Bandage for Monitoring and Treatment of Chronic Wounds
Mostafalu, P., Tamayol, A., Rahimi, R., Ochoa, M., Khalilpour, A., Kiaee, G., Yazdi, I. K., Bagherifard, S., Dokmeci, M. R., Ziaie, B., et al. (2018) · Small · doi:10.1002/smll.201703509 · Cited by 482 · see citing works
Percutaneous Transluminal Coronary Angioplasty
Landau, C., Lange, R. A., & Hillis, L. D. (1994) · New England Journal of Medicine · doi:10.1056/nejm199404073301407 · Cited by 449 · see citing works
Antibacterial and angiogenic chitosan microneedle array patch for promoting wound healing
Chi, J., Zhang, X., Chen, C., Shao, C., Zhao, Y., & Wang, Y. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.02.004 · Cited by 443 · see citing works
Rouphael, N. G., Paine, M., Mosley, R., Henry, S., McAllister, D. V., Kalluri, H., Pewin, W., Frew, P. M., Yu, T., Thornburg, N. J., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)30575-5 · Cited by 442 · see citing works
Stimulus-responsive polymeric nanogels as smart drug delivery systems
Hajebi, S., Rabiee, N., Bagherzadeh, M., Ahmadi, S., Rabiee, M., Roghani‐Mamaqani, H., Tahriri, M., Tayebi, L., & Hamblin, M. R. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.05.018 · Cited by 428 · see citing works
Advances and limitations of drug delivery systems formulated as eye drops
Jumelle, C., Gholizadeh, S., Annabi, N., & Dana, R. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.01.057 · Cited by 413 · see citing works
Genipin-crosslinked catechol-chitosan mucoadhesive hydrogels for buccal drug delivery
Xu, J., Strandman, S., Zhu, X. X., Barralet, J. E., & Cerruti, M. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.10.024 · Cited by 410 · see citing works
Stewart, S. A., Domínguez‐Robles, J., Donnelly, R. F., & Larrañeta, E. (2018) · Polymers · doi:10.3390/polym10121379 · Cited by 391 · see citing works
Reviews of wearable healthcare systems: Materials, devices and system integration
Lou, Z., Wang, L., Jiang, K., Wei, Z., & Shen, G. (2019) · Materials Science and Engineering R Reports · doi:10.1016/j.mser.2019.100523 · Cited by 389 · see citing works
An Advanced Multifunctional Hydrogel‐Based Dressing for Wound Monitoring and Drug Delivery
Mirani, B., Pagan, E., Currie, B., Siddiqui, M. A., Hosseinzadeh, R., Mostafalu, P., Zhang, Y. S., Ghahary, A., & Akbari, M. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700718 · Cited by 388 · see citing works
A melanin-mediated cancer immunotherapy patch
Ye, Y., Wang, C., Zhang, X., Hu, Q., Zhang, Y., Liu, Q., Wen, D., Milligan, J. J., Bellotti, A., Huang, L., et al. (2017) · Science Immunology · doi:10.1126/sciimmunol.aan5692 · Cited by 382 · see citing works
Recent advances of microneedles for biomedical applications: drug delivery and beyond
Yang, J. G., Liu, X., Fu, Y., & Song, Y. (2019) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2019.03.007 · Cited by 381 · see citing works
Mao, C., Xiang, Y., Liu, X., Cui, Z., Yang, X., Li, Z., Zhu, S., Zheng, Y., Yeung, K., & Wu, S. (2018) · ACS Nano · doi:10.1021/acsnano.7b08500 · Cited by 379 · see citing works
Thapa, R. K., Diep, D. B., & Tønnesen, H. H. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.12.025 · Cited by 378 · see citing works
Mechanisms of controlled drug release from drug-eluting stents
Acharya, G. S., & Park, K. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.01.016 · Cited by 363 · see citing works
Than, A., Liu, C., Chang, H., Duong, P. K., Cheung, C. M. G., Xu, C., Wang, X., & Chen, P. (2018) · Nature Communications · doi:10.1038/s41467-018-06981-w · Cited by 347 · see citing works
Coronary stents: historical development, current status and future directions
Iqbal, J., Gunn, J. P., & Serruys, P. W. J. C. (2013) · British Medical Bulletin · doi:10.1093/bmb/ldt009 · Cited by 319 · see citing works
Topical and Transdermal Drug Delivery: From Simple Potions to Smart Technologies
Benson, H. A., Grice, J. E., Mohammed, Y., Namjoshi, S., & Roberts, M. S. (2019) · Current Drug Delivery · doi:10.2174/1567201816666190201143457 · Cited by 306 · see citing works
Bioinspired Adhesive Architectures: From Skin Patch to Integrated Bioelectronics
Baik, S., Lee, H. J., Kim, D. W., Kim, J. W., Lee, Y., & Pang, C. (2019) · Advanced Materials · doi:10.1002/adma.201803309 · Cited by 305 · see citing works
Wearable and Implantable Sensors for Biomedical Applications
Koydemir, H. C., & Özcan, A. (2018) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-061417-125956 · Cited by 296 · see citing works
Su, K., Tan, L., Liu, X., Cui, Z., Zheng, Y., Li, B., Han, Y., Li, Z., Zhu, S., Liang, Y., et al. (2020) · ACS Nano · doi:10.1021/acsnano.9b08686 · Cited by 296 · see citing works
Stimuli-responsive transdermal microneedle patches
Makvandi, P., Jamaledin, R., Chen, G., Baghbantaraghdari, Z., Zare, E. N., Natale, C. D., Onesto, V., Vecchione, R., Lee, J., Tay, F. R., et al. (2021) · Materials Today · doi:10.1016/j.mattod.2021.03.012 · Cited by 285 · see citing works
History of oral contraceptive drugs and their use worldwide
Christin‐Maître, S. (2012) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2012.11.004 · Cited by 271 · see citing works
A review on therapeutic contact lenses for ocular drug delivery
Maulvi, F. A., Soni, T. G., & Shah, D. O. (2016) · Drug Delivery · doi:10.3109/10717544.2016.1138342 · Cited by 271 · see citing works
Why consider vaginal drug administration?
Alexander, N. J., Baker, E., Kaptein, M., Karck, U., Miller, L., & Zampaglione, E. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.01.025 · Cited by 269 · see citing works
Qiao, Y., Liu, X., Li, B., Han, Y., Zheng, Y., Yeung, K., Li, C., Cui, Z., Liang, Y., Li, Z., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18268-0 · Cited by 266 · see citing works
Roumen, F. J. M. E., Apter, D. L., Mulders, T. M. T., & Dieben, T. O. M. (2001) · Human Reproduction · doi:10.1093/humrep/16.3.469 · Cited by 262 · see citing works
A 3D-printed local drug delivery patch for pancreatic cancer growth suppression
Yi, H., Choi, Y., Kang, K. S., Hong, J. M., Pati, R. G., Park, M. N., Shim, I. K., Lee, C. M., Kim, S. C., & Cho, D. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.06.015 · Cited by 261 · see citing works
Graphitic carbon nitride-based materials for photocatalytic antibacterial application
Kong, X., Liu, X., Zheng, Y., Chu, P. K.-H., Zhang, Y., & Wu, S. (2021) · Materials Science and Engineering R Reports · doi:10.1016/j.mser.2021.100610 · Cited by 260 · see citing works
A Textile Dressing for Temporal and Dosage Controlled Drug Delivery
Mostafalu, P., Kiaee, G., Giatsidis, G., Khalilpour, A., Nabavinia, M., Dokmeci, M. R., Sonkusale, S., Orgill, D. P., Tamayol, A., & Khademhosseini, A. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201702399 · Cited by 256 · see citing works
Stretch-Triggered Drug Delivery from Wearable Elastomer Films Containing Therapeutic Depots
Di, J., Yao, S., Ye, Y., Cui, Z., Yu, J., Ghosh, T. K., Zhu, Y., & Gu, Z. (2015) · ACS Nano · doi:10.1021/acsnano.5b03975 · Cited by 253 · see citing works
Long-acting reversible contraception by effervescent microneedle patch
Li, W., Tang, J. T., Terry, R. N., Li, S., Brunie, A., Callahan, R. L., Noel, R. K., Rodríguez, C. A., Schwendeman, S. P., & Prausnitz, M. R. (2019) · Science Advances · doi:10.1126/sciadv.aaw8145 · Cited by 251 · see citing works
Stimulus-responsive sequential release systems for drug and gene delivery
Ahmadi, S., Rabiee, N., Bagherzadeh, M., Elmi, F., Fatahi, Y., Farjadian, F., Baheiraei, N., Nasseri, B., Rabiee, M., Dastjerd, N. T., et al. (2020) · Nano Today · doi:10.1016/j.nantod.2020.100914 · Cited by 250 · see citing works
Olsen, T., Jørgensen, O. D., Nielsen, J. C., Thøgersen, A. M., Philbert, B. T., & Johansen, J. B. (2019) · European Heart Journal · doi:10.1093/eurheartj/ehz316 · Cited by 238 · see citing works
The recent progress on metal-organic frameworks for phototherapy.
Zheng, Q.-Y., Liu, X.-M., Zheng, Y.-F., Yeung, K., Cui, Z., Liang, Y.-Q., Li, Z.-Y., Zhu, S.-L., Wang, X.-B., & Wu, S. (2021) · Chemical Society Reviews · doi:10.1039/d1cs00056j · Cited by 234 · see citing works
Interventions for pain with intrauterine device insertion
Lopez, L. M., Bernholc, A. S., Zeng, Y., Allen, R. H., Bartz, D., O'Brien, P. A., & Hubacher, D. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007373.pub3 · Cited by 232 · see citing works
Wearable and Implantable Electronics: Moving toward Precision Therapy
Song, Y., Min, J., & Gao, W. F. (2019) · ACS Nano · doi:10.1021/acsnano.9b08323 · Cited by 232 · see citing works
Liu, Z., Nie, J., Miao, B., Li, J., Cui, Y., Wang, S., Zhang, X., Zhao, G., Deng, Y., Wu, Y., et al. (2019) · Advanced Materials · doi:10.1002/adma.201807795 · Cited by 231 · see citing works
Han, D., Li, Y., Liu, X., Li, B., Han, Y. N., Zheng, Y., Yeung, K., Li, C., Cui, Z., Liang, Y., et al. (2020) · Chemical Engineering Journal · doi:10.1016/j.cej.2020.125194 · Cited by 225 · see citing works
Gutruf, P., Yin, R. T., Lee, K. B., Ausra, J., Brennan, J. A., Qiao, Y., Xie, Z., Peralta, R., Talarico, O., Murillo, A., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13637-w · Cited by 223 · see citing works
3D printing of vaginal rings with personalized shapes for controlled release of progesterone
Fu, J., Yu, X., & Jin, Y. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.01.036 · Cited by 222 · see citing works
Evolution of Insulin Delivery Devices: From Syringes, Pens, and Pumps to DIY Artificial Pancreas
Kesavadev, J., Saboo, B., Krishna, M. B., & Krishnan, G. (2020) · Diabetes Therapy · doi:10.1007/s13300-020-00831-z · Cited by 221 · see citing works
Joo, H., Lee, Y., Kim, J., Yoo, J.-S., Yoo, S., Kim, S., Arya, A. K., Kim, S. J., Choi, S. H., Lu, N., et al. (2021) · Science Advances · doi:10.1126/sciadv.abd4639 · Cited by 214 · see citing works
Dai, X., Guo, Q., Zhao, Y., Zhang, P., Zhang, T., Zhang, X., & Li, C. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b09267 · Cited by 213 · see citing works
Principles of Gender-Specific Medicine
(2010) · Elsevier eBooks · doi:10.1016/c2009-0-03574-0 · Cited by 212 · see citing works
Pons-Faudoa, F. P., Ballerini, A., Sakamoto, J. H., & Grattoni, A. (2019) · Biomedical Microdevices · doi:10.1007/s10544-019-0389-6 · Cited by 211 · see citing works
Antianginal effects of nitroglycerin patches
Reichek, N., Priest, C., Zimrin, D. A., Chandler, T., & Sutton, M. S. J. (1984) · The American Journal of Cardiology · doi:10.1016/0002-9149(84)90295-9 · Cited by 208 · see citing works
3D printing of a wearable personalized oral delivery device: A first-in-human study
Liang, K., Carmone, S., Brambilla, D., & Leroux, J. (2018) · Science Advances · doi:10.1126/sciadv.aat2544 · Cited by 208 · see citing works
Skin in the diagnostics game: Wearable biosensor nano- and microsystems for medical diagnostics
Dervisevic, M., Alba, M., Prieto‐Simón, B., & Voelcker, N. H. (2019) · Nano Today · doi:10.1016/j.nantod.2019.100828 · Cited by 205 · see citing works
Recent Advances in Wearable Transdermal Delivery Systems
Amjadi, M., Sheykhansari, S., Nelson, B. J., & Sitti, M. (2018) · Advanced Materials · doi:10.1002/adma.201704530 · Cited by 201 · see citing works
Review of Stimuli-Responsive Polymers in Drug Delivery and Textile Application
CHATTERJEE, S., & Chi-leung HUI, P. (2019) · Molecules · doi:10.3390/molecules24142547 · Cited by 201 · see citing works
In vivo performance of a drug-eluting contact lens to treat glaucoma for a month
Ciolino, J. B., Stefanescu, C. F., Ross, A. E., Salvador‐Culla, B., Cortez, P., Ford, E. M., Wymbs, K. A., Sprague, S. L., Mascoop, D. R., Rudina, S. S., et al. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.09.032 · Cited by 198 · see citing works
Tip-loaded fast-dissolving microneedle patches for photodynamic therapy of subcutaneous tumor
Zhao, X., Li, X., Zhang, P., Du, J., & Wang, Y. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.07.038 · Cited by 191 · see citing works
A Wirelessly Controlled Smart Bandage with 3D‐Printed Miniaturized Needle Arrays
Derakhshandeh, H., Aghabaglou, F., McCarthy, A., Mostafavi, A., Wiseman, C., Bonick, Z., Ghanavati, I., Harris, S., Kreikemeier‐Bower, C., Moosavi Basri, S. M., et al. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201905544 · Cited by 188 · see citing works
Choi, M. K., Park, I., Kim, D. C., Joh, E., Park, O. K., Kim, J., Kim, M., Choi, C., Yang, J., Cho, K. W., et al. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201502956 · Cited by 186 · see citing works
Wearable and Implantable Soft Bioelectronics: Device Designs and Material Strategies
Sunwoo, S., Ha, K., Lee, S., Lu, N., & Kim, D. (2021) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-101420-024336 · Cited by 186 · see citing works
Feldman, B., Brazg, R., Schwartz, S. L., & Weinstein, R. L. (2003) · Diabetes Technology & Therapeutics · doi:10.1089/152091503322526978 · Cited by 184 · see citing works
Zhu, Y., Matsumura, Y., Velayutham, M., Foley, L. M., Hitchens, T. K., & Wagner, W. R. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.05.044 · Cited by 182 · see citing works
Risk Factors for Infections Involving Cardiac Implanted Electronic Devices
Birnie, D. H., Wang, J., Alings, M., Philippon, F., Parkash, R., Manlucu, J., Angaran, P., Rinne, C., Coutu, B., Low, R. A., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.09.060 · Cited by 174 · see citing works
Gresham, G. K., Hendifar, A. E., Spiegel, B. M. R., Neeman, E., Tuli, R., Rimel, B. J., Figlin, R. A., Meinert, C. L., Piantadosi, S., & Shinde, A. M. (2018) · npj Digital Medicine · doi:10.1038/s41746-018-0032-6 · Cited by 172 · see citing works
A self-adherent, bullet-shaped microneedle patch for controlled transdermal delivery of insulin
Seong, K., Seo, M., Hwang, D. Y., O’Cearbhaill, E. D., Sreenan, S., Karp, J. M., & Yang, S. Y. (2017) · Journal of Controlled Release · doi:10.1016/j.jconrel.2017.03.041 · Cited by 171 · see citing works
Fu, J., Li, Y., Zhang, Y., Liang, Y., Zheng, Y., Li, Z., Zhu, S., Li, C., Cui, Z., & Wu, S. (2021) · Advanced Materials · doi:10.1002/adma.202102926 · Cited by 169 · see citing works
Luo, Y. Y., Liu, X., Tan, L., Li, Z., Yeung, K., Zheng, Y., Cui, Z., Liang, Y., Zhu, S., Li, C., et al. (2020) · Chemical Engineering Journal · doi:10.1016/j.cej.2020.126730 · Cited by 167 · see citing works
Bhatnagar, S., Bankar, N. G., Kulkarni, M. V., & Venuganti, V. V. K. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.12.022 · Cited by 165 · see citing works
Intradermal delivery of STAT3 siRNA to treat melanoma via dissolving microneedles
Pan, J., Ruan, W., Qin, M., Long, Y., Wan, T. Y., Yu, K., Zhai, Y., Wu, C., & Xu, Y. (2018) · Scientific Reports · doi:10.1038/s41598-018-19463-2 · Cited by 157 · see citing works
Masumoto, H., Matsuo, T., Yamamizu, K., Uosaki, H., Narazaki, G., Katayama, S., Marui, A., Shimizu, T., Ikeda, T., Okano, T., et al. (2012) · Stem Cells · doi:10.1002/stem.1089 · Cited by 154 · see citing works
Vascular endothelial growth factor: Biology and therapeutic applications
Ho, Q. T., & Kuo, C. J. (2007) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2007.04.010 · Cited by 153 · see citing works
The Newest Generation of Drug-eluting Stents and Beyond
Lee, D., & Hernández, J. M. D. L. T. (2018) · European Cardiology Review · doi:10.15420/ecr.2018:8:2 · Cited by 152 · see citing works
Dermal Patch with Integrated Flexible Heater for on Demand Drug Delivery
Bagherifard, S., Tamayol, A., Mostafalu, P., Akbari, M., Comotto, M., Annabi, N., Ghaderi, M., Sonkusale, S., Dokmeci, M. R., & Khademhosseini, A. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201500357 · Cited by 151 · see citing works
Guan, W., Tan, L., Liu, X., Cui, Z., Zheng, Y., Yeung, K., Zheng, D., Liang, Y., Li, Z., Zhu, S., et al. (2020) · Advanced Materials · doi:10.1002/adma.202006047 · Cited by 147 · see citing works
Chen, M., Ling, M.-H., & Kusuma, S. J. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.06.021 · Cited by 145 · see citing works
Economidou, S. N., Uddin, M. J., Marques, M. J. M., Douroumis, D., Sow, W. T., Li, H., Reid, A., Windmill, J. F. C., & Podoleanu, A. G. (2020) · Additive manufacturing · doi:10.1016/j.addma.2020.101815 · Cited by 145 · see citing works
Du, S., Zhou, N., Xie, G., Chen, Y., Suo, H., Xu, J., Tao, J., Zhang, L., & Zhu, J. (2021) · Nano Energy · doi:10.1016/j.nanoen.2021.106004 · Cited by 145 · see citing works
Chitosan oral patches inspired by mussel adhesion
Ryu, J. H., Choi, J. S., Park, E., Eom, M. R., Jo, S., Lee, M. S., Kwon, S. K., & Lee, H. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.11.006 · Cited by 144 · see citing works
Non-transdermal microneedles for advanced drug delivery
Lee, K., Goudie, M. J., Tebon, P. J., Sun, W., Luo, Z., Lee, J., Zhang, S., Fetah, K., Kim, H., Xue, Y., et al. (2019) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2019.11.010 · Cited by 142 · see citing works
Enzymatic Fuel Cells: Towards Self-Powered Implantable and Wearable Diagnostics
Gonzalez-Solino, C., & Lorenzo, M. D. (2018) · Biosensors · doi:10.3390/bios8010011 · Cited by 140 · see citing works
Yao, Y., Ding, J., Wang, Z., Zhang, H., Xie, J., Wang, Y., Hong, L., Mao, Z., Gao, J., & Gao, C. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119726 · Cited by 137 · see citing works
Mussel-inspired hydrogel tissue adhesives for wound closure
Rahimnejad, M., & Zhong, W. (2017) · RSC Adv. · doi:10.1039/c7ra06743g · Cited by 135 · see citing works
Phase‐Transition Microneedle Patches for Efficient and Accurate Transdermal Delivery of Insulin
Yang, S., Wu, F., Liu, J., Fan, G., Welsh, W. J., Zhu, H., & Jin, T. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201500554 · Cited by 132 · see citing works
Han, D., Li, Y., Liu, X., Yeung, K., Zheng, Y., Cui, Z., Liang, Y., Li, Z., Zhu, S., Wang, X., et al. (2020) · Journal of Material Science and Technology · doi:10.1016/j.jmst.2020.05.055 · Cited by 131 · see citing works
Long-Term Safety and Efficacy With Paclitaxel-Eluting Stents
Ellis, S. G., Stone, G. W., Cox, D. A., Hermiller, J. B., O’Shaughnessy, C. D., Mann, T., Turco, M. A., Caputo, R. P., Bergin, P. J., Bowman, T. S., et al. (2009) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2009.10.003 · Cited by 129 · see citing works
Vong, L. B., Bui, T. Q., Tomita, T., Sakamoto, H., Hiramatsu, Y., & Nagasaki, Y. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.03.023 · Cited by 129 · see citing works
5-Aminolevulinic acid coated microneedles for photodynamic therapy of skin tumors
Jain, A., Lee, C. H., & Gill, H. S. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.08.015 · Cited by 128 · see citing works
Ayyala, R. S., Zurakowski, D., Monshizadeh, R., Hong, C.-H., Richards, D., Layden, W. E., Hutchinson, B. T., & Bellows, A. R. (2002) · Ophthalmic surgery, lasers & imaging retina · doi:10.3928/1542-8877-20020301-04 · Cited by 125 · see citing works
Topical sustained drug delivery to the retina with a drug-eluting contact lens
Ross, A. E., Bengani, L. C., Tulsan, R., Maidana, D. E., Salvador‐Culla, B., Kobashi, H., Kolovou, P. E., Zhai, H., Taghizadeh, K., Kuang, L., et al. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119285 · Cited by 125 · see citing works
Colley, H. E., Said, Z., Santocildes‐Romero, M. E., Baker, S. R., D’Apice, K., Hansen, J., Madsen, L. S., Thornhill, M. H., Hatton, P. V., & Murdoch, C. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.06.009 · Cited by 124 · see citing works
Biomaterial‐Based Implantable Devices for Cancer Therapy
Chew, S. A., & Danti, S. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201600766 · Cited by 121 · see citing works
Wang, H., Pastorin, G., & Lee, C. (2016) · Advanced Science · doi:10.1002/advs.201500441 · Cited by 118 · see citing works
Iontophoresis-Driven Porous Microneedle Array Patch for Active Transdermal Drug Delivery
Li, Y., Yang, J., Zheng, Y., Ye, R., Liu, B., Huang, Y. X., Zhou, W., & Jiang, L. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.12.023 · Cited by 117 · see citing works
Six-Month Intraocular Pressure Reduction with a Topical Bimatoprost Ocular Insert
Brandt, J. D., Sall, K. N., Dubiner, H. B., Benza, R., Alster, Y., Walker, G. A., Semba, C. P., Budenz, D. L., Day, D. G., Flowers, B. E., et al. (2016) · Ophthalmology · doi:10.1016/j.ophtha.2016.04.026 · Cited by 116 · see citing works
Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway
Tang, J., Wang, J., Kong, X., Yang, J., Guo, L., Zheng, F. Y., Zhang, L., Huang, Y.-Z., & Wan, Y. (2009) · Experimental Cell Research · doi:10.1016/j.yexcr.2009.09.026 · Cited by 115 · see citing works
Injectable chitosan hydrogel embedding modified halloysite nanotubes for bone tissue engineering
Kazemi-Aghdam, F., Jahed, V., Dehghan-Niri, M., Ganji, F., & Vasheghani‐Farahani, E. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.118311 · Cited by 112 · see citing works
Napavichayanun, S., Yamdech, R., & Aramwit, P. (2016) · Archives of Dermatological Research · doi:10.1007/s00403-016-1621-3 · Cited by 110 · see citing works
Corneal delivery of besifloxacin using rapidly dissolving polymeric microneedles
Bhatnagar, S., Saju, A., Cheerla, K. D., Gade, S. K., Garg, P., & Venuganti, V. V. K. (2017) · Drug Delivery and Translational Research · doi:10.1007/s13346-017-0470-8 · Cited by 107 · see citing works
Biodegradable polymeric injectable implants for long‐term delivery of contraceptive drugs
Manoukian, O. S., Arul, M. R., Sardashti, N., Stedman, T., James, R., Rudraiah, S., & Kumbar, S. G. (2017) · Journal of Applied Polymer Science · doi:10.1002/app.46068 · Cited by 105 · see citing works
Glycaemic control in pancreatectomized dogs with a wearable artificial endocrine pancreas
Shichiri, M., Kawamori, R., Goriya, Y., Yamasaki, Y., Nomura, M., Hakui, N., & Abe, H. (1983) · Diabetologia · doi:10.1007/bf00250158 · Cited by 104 · see citing works
Role of Oxidative Stress in Cardiac Remodelling after Myocardial Infarction
Grieve, D., Byrne, J., Cave, A. C., & Shah, A. M. (2004) · Heart Lung and Circulation · doi:10.1016/j.hlc.2004.02.008 · Cited by 104 · see citing works
Yao, G., Quan, G., Lin, S., Peng, T., Wang, Q., Ran, H., Chen, H., Zhang, Q. Y., Wang, L., Pan, X., et al. (2017) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2017.10.035 · Cited by 103 · see citing works
E-jet 3D printed drug delivery implants to inhibit growth and metastasis of orthotopic breast cancer
Yang, Y., Qiao, X., Huang, R., Chen, H., Shi, X., Wang, J., Tan, W., & Tan, Z. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119618 · Cited by 103 · see citing works
Drug-eluting Stents: Potential Applications for Peripheral Arterial Occlusive Disease
Duda, S. H., Poerner, T. C., Wiesinger, B., Rundback, J. H., Tepe, G., Wiskirchen, J., & Haase, K. K. (2003) · Journal of Vascular and Interventional Radiology · doi:10.1097/01.rvi.0000058423.01661.57 · Cited by 102 · see citing works
Korkmaz, E., Friedrich, E. E., Ramadan, M. H., Erdös, G., Mathers, A. R., Özdoğanlar, O. B., Washburn, N. R., & Falo, L. D. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.05.036 · Cited by 100 · see citing works
Recent advances in intraocular sustained-release drug delivery devices
Cao, Y., Samy, K. E., Bernards, D. A., & Desai, T. A. (2019) · Drug Discovery Today · doi:10.1016/j.drudis.2019.05.031 · Cited by 99 · see citing works
Manikkath, J., & Subramony, J. A. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.113997 · Cited by 98 · see citing works
Silk Fibroin Microneedle Patches for the Sustained Release of Levonorgestrel
Yavuz, B., Chambre, L., Harrington, K., Kluge, J. A., Valenti, L., & Kaplan, D. L. (2020) · ACS Applied Bio Materials · doi:10.1021/acsabm.0c00671 · Cited by 95 · see citing works
Chung, H. J., Kim, J., Kim, H.-J., Kyung, H., Katila, P., Lee, J.-H., Yang, T., Yang, Y., & Lee, S. J. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.02.013 · Cited by 93 · see citing works
Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer
Shapira‐Furman, T., Serra, R., Gorelick, N. L., Doglioli, M., Tagliaferri, V., Cecia, A. F., Peters, M., Kumar, A., Rottenberg, Y., Langer, R., et al. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.12.048 · Cited by 93 · see citing works
Immunomodulatory nanosystems for treating inflammatory diseases
Ahamad, N., Kar, A., Mehta, S., Dewani, M., Ravichandran, V., Bhardwaj, P., Sharma, S., & Banerjee, R. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.120875 · Cited by 88 · see citing works
Self-citationDesai, A. R., Maulvi, F. A., Pandya, M. M., Ranch, K. M., Vyas, B., Shah, S. A., & Shah, D. O. (2018) · Biomaterials Science · doi:10.1039/c8bm00212f · Cited by 87 · see citing works
Contact lenses with dual drug delivery for the treatment of bacterial conjunctivitis
Maulvi, F. A., Singhania, S. S., Desai, A. R., Shukla, M. R., Tannk, A. S., Ranch, K. M., Vyas, B., & Shah, D. O. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.06.059 · Cited by 87 · see citing works
Tunable injectable alginate-based hydrogel for cell therapy in Type 1 Diabetes Mellitus
Espona‐Noguera, A., Ciriza, J., Cañibano-Hernández, A., Fernández, L. J., Ochoa, I., del Burgo, L. S., & Pedraz, J. L. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.09.103 · Cited by 82 · see citing works
He, M., Yang, G., Zhang, S., Zhao, X., & Gao, Y. (2017) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2017.11.013 · Cited by 82 · see citing works
Mun, J., Mok, J. W., Jeong, S., Cho, S., Joo, C.-K., & Hahn, S. K. (2019) · RSC Advances · doi:10.1039/c9ra02858g · Cited by 82 · see citing works
PVA/SA/TiO2-CUR patch for enhanced wound healing application: In vitro and in vivo analysis
Niranjan, R. S., Kaushik, M., Selvi, R. T., Prakash, J., Venkataprasanna, K. S., Prema, D., Balashanmugam, P., & Venkatasubbu, G. D. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.07.125 · Cited by 81 · see citing works
Bioinspired multilayer membranes as potential adhesive patches for skin wound healing
Sousa, M. P., Neto, A. I., Correia, T. R., Miguel, S. P., Matsusaki, M., Correia, I. J., & Mano, J. F. (2018) · Biomaterials Science · doi:10.1039/c8bm00319j · Cited by 78 · see citing works
Orbital implants: State-of-the-art review with emphasis on biomaterials and recent advances
Baino, F., & Potestio, I. (2016) · Materials Science and Engineering C · doi:10.1016/j.msec.2016.08.003 · Cited by 77 · see citing works
Proctor, C. M., Uguz, I., Slézia, A., Curto, V. F., Inal, S., Williamson, A., & Malliaras, G. G. (2018) · Advanced Biosystems · doi:10.1002/adbi.201800270 · Cited by 77 · see citing works
Joshi, A., Xu, Z., Ikegami, Y., Yoshida, K., Sakai, Y., Joshi, A., Kaur, T., Nakao, Y., Yamashita, Y., Baba, H., et al. (2020) · Chemical Engineering Journal · doi:10.1016/j.cej.2020.126518 · Cited by 77 · see citing works
Gong, M., Yue, L., Kong, J., Lin, X., Zhang, L., Wang, J., & Wang, D. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c00864 · Cited by 77 · see citing works
Chua, C. Y. X., Jain, P., Ballerini, A., Bruno, G., Hood, R. L., Gupte, M., Gao, S., Trani, N. D., Šušnjar, A., Shelton, K. A., et al. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.08.010 · Cited by 76 · see citing works
Chen, B. Z., Ashfaq, M., Zhu, D., Zhang, X. P., & Guo, X. D. (2018) · Macromolecular Rapid Communications · doi:10.1002/marc.201800075 · Cited by 74 · see citing works
Zhou, C., Robert, M.-C., Kapoulea, V., Lei, F., Stagner, A. M., Jakobiec, F. A., Dohlman, C. H., & Paschalis, E. I. (2017) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.16-20339 · Cited by 72 · see citing works
Li, D., Lv, P., Fan, L., Huang, Y., Yang, F., Mei, X., & Wu, D. (2017) · Biomaterials Science · doi:10.1039/c7bm00693d · Cited by 72 · see citing works
Ruan, W., Zhai, Y., Yu, K., Wu, C., & Xu, Y. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.10.043 · Cited by 72 · see citing works
Interventions for pain with intrauterine device insertion
Allen, R. H., Bartz, D., Grimes, D. A., Hubacher, D., & O'Brien, P. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007373.pub2 · Cited by 72 · see citing works
Preparation of functionalized cotton fabrics by means of melatonin loaded β-cyclodextrin nanosponges
Mihailiasa, M., Caldera, F., Li, J., Peila, R., Ferri, A., & Trotta, F. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.01.024 · Cited by 71 · see citing works
Chaudhari, P., Ghate, V., & Lewis, S. A. (2021) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2021.02.007 · Cited by 71 · see citing works
Evaluation of commercial soft contact lenses for ocular drug delivery: A review
Fan, X., Torres-Luna, C., Azadi, M., Domszy, R. C., Hu, N., Yang, A., & David, A. E. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.08.025 · Cited by 70 · see citing works
Won, J. Y., Kim, J., Gao, G., Kim, J., Jang, J., Park, Y.-H., & Cho, D. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2020.09.015 · Cited by 70 · see citing works
Coughlin, S. S., Caplan, L. S., & Stone, R. B. (2020) · Journal of Cancer Survivorship · doi:10.1007/s11764-020-00855-1 · Cited by 69 · see citing works
Paredes, A. J., Ramöller, I. K., McKenna, P. E., Abbate, M. T. A., Volpe‐Zanutto, F., Vora, L. K., Kilbourne‐Brook, M., Jarrahian, C., Moffatt, K., Zhang, C., et al. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.04.002 · Cited by 69 · see citing works
Intelligent automated drug administration and therapy: future of healthcare
Sharma, R., Singh, D., Gaur, P., & Joshi, D. (2021) · Drug Delivery and Translational Research · doi:10.1007/s13346-020-00876-4 · Cited by 68 · see citing works
Han, D., Ma, M., Han, Y., Cui, Z., Liang, Y., Liu, X., Li, Z., Zhu, S., & Wu, S. (2019) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.9b06045 · Cited by 67 · see citing works
Anirudhan, T. S., Nair, S. S., & Nair, A. S. (2016) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2016.06.101 · Cited by 65 · see citing works
de Ávila, É. D., Castro, A. G. B., Tagit, O., Krom, B. P., Löwik, D. W. P. M., van Well, A. A., Bannenberg, L. J., Vergani, C. E., & van den Beucken, J. J. J. P. (2019) · Applied Surface Science · doi:10.1016/j.apsusc.2019.05.154 · Cited by 65 · see citing works
Effect of Race and Ethnicity on Outcomes With Drug-Eluting and Bare Metal Stents
Kumar, R., Douglas, P. S., Peterson, E. D., Anstrom, K. J., Dai, D., Brennan, J. M., Hui, P., Booth, M. E., Messenger, J. C., & Shaw, R. E. (2013) · Circulation · doi:10.1161/circulationaha.113.001437 · Cited by 64 · see citing works
Soto, F., Jeerapan, I., Silva‐López, C., Lopez‐Ramirez, M. A., Chai, I., Lu, X., Lv, J., Kurniawan, J. F., Martin, I., Chakravarthy, K. V., et al. (2018) · Small · doi:10.1002/smll.201803266 · Cited by 64 · see citing works
Sivasankaran, S., & Jonnalagadda, S. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.12.044 · Cited by 64 · see citing works
Steroid-Eluting Contact Lenses for Corneal and Intraocular InflammationPreprint
Bengani, L. C., Kobashi, H., Ross, A. E., Zhai, H., Salvador‐Culla, B., Tulsan, R., Kolovou, P. E., Mittal, S. K., Chauhan, S. K., Kohane, D. S., et al. (2020) · SSRN Electronic Journal · doi:10.1016/j.actbio.2020.08.013 · Cited by 63 · see citing works
Kazek‐Kęsik, A., Nosol, A., Płonka, J., Śmiga‐Matuszowicz, M., Gołda‐Cępa, M., Krok−Borkowicz, M., Brzychczy‐Włoch, M., Pamuła, E., & Simka, W. (2018) · Materials Science and Engineering C · doi:10.1016/j.msec.2018.10.049 · Cited by 62 · see citing works
A nanoliter resolution implantable micropump for murine inner ear drug delivery
Forouzandeh, F., Zhu, X., Alfadhel, A., Ding, B., Walton, J. P., Cormier, D., Frisina, R. D., & Borkholder, D. A. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.01.032 · Cited by 61 · see citing works
Wei, L., Wu, S., Shi, W., Aldrich, A. L., Kielian, T., Carlson, M. A., Sun, R., Qin, X., & Duan, B. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b10379 · Cited by 61 · see citing works
Vimal, S. K., Ahamad, N., & Katti, D. S. (2016) · Materials Science and Engineering C · doi:10.1016/j.msec.2016.03.008 · Cited by 60 · see citing works
Self-citationXu, L., Wang, S., Xu, C., Han, D., Ren, X., Zhang, X., & Cheng, S. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b11263 · Cited by 60 · see citing works
Skin penetration and antioxidant effect of cosmeto-textiles with gallic acid
Alonso, C., Martı́, M., Barba, C., Arias, M. J. L., Rubio Toledano, L., & Coderch, L. (2016) · UPCommons institutional repository (Universitat Politècnica de Catalunya) · doi:10.1016/j.jphotobiol.2016.01.014 · Cited by 59 · see citing works
O'Neill, H. S., O’Sullivan, J., Porteous, N., Ruiz‐Hernández, E., Kelly, H. M., O’Brien, F. J., & Duffy, G. P. (2016) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.2392 · Cited by 59 · see citing works
Stable antibacterial polysaccharide-based hydrogels as tissue adhesives for wound healing
Tang, X., Gu, X., Wang, Y., Chen, X., Ling, J., & Yang, Y. (2020) · RSC Advances · doi:10.1039/d0ra02017f · Cited by 59 · see citing works
Remotely controlled nanofluidic implantable platform for tunable drug delivery
Trani, N. D., Silvestri, A., Bruno, G., Geninatti, T., Chua, C. Y. X., Gilbert, A. L., Rizzo, G. S., Filgueira, C. S., Demarchi, D., & Grattoni, A. (2019) · Lab on a Chip · doi:10.1039/c9lc00394k · Cited by 58 · see citing works
Intravitreal implantable magnetic micropump for on-demand VEGFR-targeted drug delivery
Wang, C., Seo, S., Kim, J. S., Lee, S., Jeon, J.-K., Kim, J.-W., Kim, K., Kim, J.-K., & Park, J. (2018) · Journal of Controlled Release · doi:10.1016/j.jconrel.2018.05.030 · Cited by 56 · see citing works
Liu, Z., Li, Y., Li, W., Lian, W., Kemell, M., Hietala, S., Figueiredo, P., Li, L., Mäkilä, E. M., Ma, M., et al. (2018) · Materials Horizons · doi:10.1039/c8mh01145a · Cited by 56 · see citing works
Zhu, Q., Cheng, H., Huo, Y., & Mao, S. (2018) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2018.04.004 · Cited by 55 · see citing works
Direct site-specific treatment of skin cancer using doxorubicin-loaded nanofibrous membranes
Guo, M., Zhou, G., Liu, Z., Liu, J., Tang, J., Xiao, Y., Xu, W., Liu, Y., & Chen, C. (2017) · 中国科学通报:英文版 · doi:10.1016/j.scib.2017.11.018 · Cited by 54 · see citing works
Adherence to Medication: A Review of Existing Research
Horne, R. (2020) · CRC Press eBooks · doi:10.1201/9781003072348-15 · Cited by 53 · see citing works
Multifunctional High‐Power Sources for Smart Contact Lenses
Takamatsu, T., Yin, S., Shujie, F., Liu, X., & Miyake, T. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201906225 · Cited by 52 · see citing works
Are Drug-Eluting Stents Cost-Effective?
Ryan, J. W., & Cohen, D. J. (2006) · Circulation · doi:10.1161/circulationaha.105.546010 · Cited by 51 · see citing works
New developments in intrauterine device use: focus on the US
Nelson, A. L., & Massoudi, N. (2016) · Open Access Journal of Contraception · doi:10.2147/oajc.s85755 · Cited by 51 · see citing works
Zemljič, L. F., Peršin, Z., Šauperl, O., Rudolf, A., & Kostić, M. (2017) · Textile Research Journal · doi:10.1177/0040517517725117 · Cited by 50 · see citing works
Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES
McBride, J. W., Boyd, P., Dias, N., Cameron, D., Offord, R. E., Hartley, O., Kett, V. L., & Malcolm, K. R. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.02.003 · Cited by 48 · see citing works
Electrothermal patches driving the transdermal delivery of insulin
Pagneux, Q., Ye, R., Li, C., Barras, A., Hennuyer, N., Staels, B., Caina, D., Osses, J. A., Abderrahmani, A., Plaisance, V., et al. (2019) · Nanoscale Horizons · doi:10.1039/c9nh00576e · Cited by 48 · see citing works
Long-term drug delivery using implantable electrospun woven polymeric nanotextiles
Padmakumar, S., Paul‐Prasanth, B., Pavithran, K., Vijaykumar, D. K., Rajanbabu, A., Sivanarayanan, T. B., Kadakia, E., Amiji, M. M., Nair, S. V., & Menon, D. (2018) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2018.10.002 · Cited by 47 · see citing works
Stimulus-Responsive Contact Lens for IOP Measurement or Temperature-Triggered Drug Release
Lee, S., Shin, K., Kim, J.-W., Kang, J., & Kim, J.-K. (2020) · Translational Vision Science & Technology · doi:10.1167/tvst.9.4.1 · Cited by 47 · see citing works
On-Demand Drug Release from Gold Nanoturf for a Thermo- and Chemotherapeutic Esophageal Stent
Lee, S., Hwang, G., Kim, T. H., Kwon, S. J., Kim, J. U., Koh, K., Park, B., Hong, H., Yu, K. J., Chae, H., et al. (2018) · ACS Nano · doi:10.1021/acsnano.8b01921 · Cited by 44 · see citing works
Inner layer-embedded contact lenses for ion-triggered controlled drug delivery
Zhu, Q., Wei, Y., Li, C., & Mao, S. (2018) · Materials Science and Engineering C · doi:10.1016/j.msec.2018.07.065 · Cited by 44 · see citing works
A novel treatment strategy for preterm birth: Intra-vaginal progesterone-loaded fibrous patches
Çam, M. E., Hazar‐Yavuz, A. N., Cesur, S., Özkan, O., Alenezi, H., Şaşmazel, H. T., Eroğlu, M. S., Brako, F., Ahmed, J., Kabasakal, L., et al. (2020) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2020.119782 · Cited by 44 · see citing works
Henry, R. R., Rosenstock, J., Logan, D. K., Alessi, T. R., Luskey, K. L., & Baron, M. A. (2013) · Diabetes Care · doi:10.2337/dc12-2410 · Cited by 43 · see citing works
Mechanical testing methods for drug-releasing vaginal rings
McCoy, C. F., Millar, B., Murphy, D. J., Blanda, W., Hansraj, B., Devlin, B., Malcolm, K. R., & Boyd, P. (2019) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2019.01.026 · Cited by 43 · see citing works
A concise review on drug-loaded electrospun nanofibres as promising wound dressings
Aavani, F., Khorshidi, S., & Karkhaneh, A. (2019) · Journal of Medical Engineering & Technology · doi:10.1080/03091902.2019.1606950 · Cited by 43 · see citing works
DUROS® Technology Delivers Peptides and Proteins at Consistent Rate Continuously for 3 to 12 Months
Rohloff, C. M., Alessi, T. R., Yang, B., Dahms, J., Carr, J. P., & Lautenbach, S. D. (2008) · Journal of Diabetes Science and Technology · doi:10.1177/193229680800200316 · Cited by 42 · see citing works
Frequency-controlled wireless shape memory polymer microactuator for drug delivery application
Zainal, M. A., Ahmad, A. R., & Ali, M. S. M. (2017) · Biomedical Microdevices · doi:10.1007/s10544-017-0148-5 · Cited by 42 · see citing works
Pastori, D., Miyazawa, K., Li, Y., Shahid, F., Hado, H., & Lip, G. Y. H. (2018) · Clinical Research in Cardiology · doi:10.1007/s00392-018-1244-0 · Cited by 42 · see citing works
Silva, D., de Sousa, H. C., Gil, M. H., Santos, L. F., Moutinho, G., Salema‐Oom, M., Alvarez‐Lorenzo, C., Serro, A. P., & Saramago, B. (2020) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2020.119506 · Cited by 42 · see citing works
Kim, S., Dangol, M., Kang, G., Lahiji, S. F., Yang, H., Jang, M., Ma, Y., Li, C., Lee, S. G., Kim, C. H., et al. (2017) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.7b00111 · Cited by 41 · see citing works
Mori, H., Cheng, Q., Lutter, C., Smith, S., Guo, L., Kutyna, M. D., Torii, S., Harari, E., Acampado, E., Joner, M., et al. (2017) · JACC: Cardiovascular Interventions · doi:10.1016/j.jcin.2017.06.059 · Cited by 41 · see citing works
Titanium Implants and Local Drug Delivery Systems Become Mutual Promoters in Orthopedic Clinics
Ma, X., Gao, Y. L., Zhao, D., Zhang, W., Zhao, W., Wu, M. Y., Cui, Y., Li, Q., Zhang, Z., & Ma, C. (2021) · Nanomaterials · doi:10.3390/nano12010047 · Cited by 41 · see citing works
Stem Cells Improve Left Ventricular Function in Acute Myocardial Infarction
Singh, S., Arora, R. R., Handa, K., Khraisat, A. S., Nagajothi, N., Molnár, J., & Khosla, S. (2009) · Clinical Cardiology · doi:10.1002/clc.20470 · Cited by 40 · see citing works
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Wang, C., He, T., Zhou, H., Zhang, Z., & Lee, C. (2023) · Bioelectronic Medicine · doi:10.1186/s42234-023-00118-1 · Cited by 295 · see citing works
Flexible and Stretchable Light-Emitting Diodes and Photodetectors for Human-Centric Optoelectronics
Chang, S., Koo, J. H., Yoo, J., Kim, M. S., Choi, M. K., Kim, D., & Song, Y. M. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00548 · Cited by 209 · see citing works
Xiang, Y., Lu, J., Mao, C., Zhu, Y., Wang, C., Wu, J., Liu, X., Wu, S., Kwan, K. Y.-H., Cheung, K., et al. (2023) · Science Advances · doi:10.1126/sciadv.adf0854 · Cited by 192 · see citing works
Digital health: trends, opportunities and challenges in medical devices, pharma and bio-technology
Kasoju, N., Remya, N. S., Sasi, R., Sreedharan, S., Soman, B., Kesavadas, C., Muraleedharan, C. V., Varma, P. R. H., & Behari, S. (2023) · CSI Transactions on ICT · doi:10.1007/s40012-023-00380-3 · Cited by 180 · see citing works
Kumarasamy, R. V., Natarajan, P. M., Umapathy, V. R., Roy, J. R., Mironescu, M., & Palanisamy, C. P. (2024) · Frontiers in Nanotechnology · doi:10.3389/fnano.2024.1479993 · Cited by 150 · see citing works
Smart Dual‐Sensor Wound Dressing for Monitoring Cutaneous Wounds
Mirani, B., Hadisi, Z., Pagan, E., Dabiri, S. M. H., van Rijt, A., Almutairi, L., Noshadi, I., Armstrong, D. G., & Akbari, M. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202203233 · Cited by 132 · see citing works
Material and structural considerations for high-performance electrodes for wearable skin devices
Lim, K., Seo, H., Chung, W. G., Song, H., Oh, M., Ryu, S. Y., Kim, Y., & Park, J. (2024) · Communications Materials · doi:10.1038/s43246-024-00490-8 · Cited by 127 · see citing works
Review of Flexible Wearable Sensor Devices for Biomedical Application
Nan, X., Wang, X., Kang, T., Zhang, J., Dong, L., Dong, J., Xia, P., & Wei, D. (2022) · Micromachines · doi:10.3390/mi13091395 · Cited by 109 · see citing works
Liu, X., Guo, C., Yang, W., Wang, W., Diao, N., Cao, M., Cao, Y., Wang, X., Wang, X., Pei, H., et al. (2024) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2024.122574 · Cited by 105 · see citing works
Stasevych, M., & Zvarych, V. I. (2023) · Big Data and Cognitive Computing · doi:10.3390/bdcc7030147 · Cited by 110 · see citing works
Advancements in Wearable and Implantable BioMEMS Devices: Transforming Healthcare Through Technology
Abhinav, V., Basu, P., Verma, S. S., Verma, J., Das, A., Kumari, S., Yadav, P. R., & Kumar, V. (2025) · Micromachines · doi:10.3390/mi16050522 · Cited by 102 · see citing works
Materials and device design for advanced phototherapy systems
Lee, J. S., Kim, J., Ye, Y., & Kim, T. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114339 · Cited by 82 · see citing works
Materials design and integration strategies for soft bioelectronics in digital healthcare
Kim, H. J., Koo, J. H., Lee, S., Hyeon, T., & Kim, D. (2025) · Nature Reviews Materials · doi:10.1038/s41578-025-00819-w · Cited by 87 · see citing works
Dual drug-loaded hydrogels with pH-responsive and antibacterial activity for skin wound dressing
Du, M., Jin, J., Zhou, F., Chen, J., & Jiang, W. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.113063 · Cited by 78 · see citing works
Soft Bioelectronics for Therapeutics
Zhang, Z., Zhu, Z., Zhou, P., Zou, Y., Yang, J., Haick, H., & Wang, Y. (2023) · ACS Nano · doi:10.1021/acsnano.3c02513 · Cited by 79 · see citing works
Remote‐Controlled Sensing and Drug Delivery via 3D‐Printed Hollow Microneedles
Razzaghi, M., Ninan, J. A., Azimzadeh, M., Askari, E., Najafabadi, A. H., Khademhosseini, A., & Akbari, M. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202400881 · Cited by 78 · see citing works
Electroactive Polymers for On‐Demand Drug Release
Alkahtani, M. E., Elbadawi, M., Chapman, C. A. R., Green, R. A., Gaisford, S., Orlu, M., & Basit, A. W. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301759 · Cited by 76 · see citing works
He, T., Wen, F., Yang, Y., Le, X., Liu, W., & Lee, C. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.2c04527 · Cited by 74 · see citing works
Therapeutic applications of contact lens-based drug delivery systems in ophthalmic diseases
Zhao, L., Song, J., Du, Y., Ren, C., Guo, B., & Bi, H. (2023) · Drug Delivery · doi:10.1080/10717544.2023.2219419 · Cited by 75 · see citing works
Biomedical Metal–Organic framework materials on antimicrobial therapy: Perspectives and challenges
Hu, W., Ouyang, Q., Jiang, C., Huang, S., Nezamzadeh‐Ejhieh, A., Guo, D., Liu, J., & Peng, Y. (2024) · Materials Today Chemistry · doi:10.1016/j.mtchem.2024.102300 · Cited by 70 · see citing works
Recent advances of smart materials for ocular drug delivery
Wang, X., Luan, F., Yue, H., Song, C., Wang, S., Feng, J., Zhang, X., Yang, W. H., Li, Y., Wei, W., et al. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.115006 · Cited by 69 · see citing works
Artificial intelligence in smart drug delivery systems: a step toward personalized medicine
Panchpuri, M., Painuli, R., & Kumar, C. (2025) · RSC Pharmaceutics · doi:10.1039/d5pm00089k · Cited by 65 · see citing works
Hydrogel-Coated SERS Microneedles for Drug Monitoring in Dermal Interstitial Fluid
Yan, L., Wang, Y., Mei, R., Lv, B., Zhao, X., Bi, L., Xu, H. Z., & Chen, L. (2024) · ACS Sensors · doi:10.1021/acssensors.4c00276 · Cited by 58 · see citing works
Microfluidic technologies for wearable and implantable biomedical devices
Wang, Z., Shah, A., Lee, H., & Lee, C. H. (2025) · Lab on a Chip · doi:10.1039/d5lc00499c · Cited by 61 · see citing works
Naeem, A., Yu, C., Zhu, W., Chen, X., Wu, X., Chen, L., Zang, Z., & Guan, Y. (2022) · Molecules · doi:10.3390/molecules27238397 · Cited by 56 · see citing works
Yadav, A. A., Hunge, Y. M., Majumder, S., Islam, M. M., & Sakurai, T. (2025) · Energy & Fuels · doi:10.1021/acs.energyfuels.5c01661 · Cited by 54 · see citing works
Recent advances in the material design for intelligent wearable devices
Wu, Y., Li, Y., Tao, Y., Sun, L., & Yu, C. (2023) · Materials Chemistry Frontiers · doi:10.1039/d3qm00076a · Cited by 53 · see citing works
Degradable and Recyclable Hydrogels for Sustainable Bioelectronics
Jia, L., Li, Y., Ren, A., Xiang, T., & Zhou, S. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c05663 · Cited by 51 · see citing works
Drug Delivery Systems for Personal Healthcare by Smart Wearable Patch System
Khadka, B., Lee, B., & Kim, K.-T. (2023) · Biomolecules · doi:10.3390/biom13060929 · Cited by 48 · see citing works
Zhi, Y., Che, J., Zhu, H., Liu, R., & Zhao, Y. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202304353 · Cited by 45 · see citing works
Sun, Y., Liu, M., Sun, W., Tang, X., Zhou, Y., Zhang, J., & Yang, B. J. (2024) · Advanced Materials · doi:10.1002/adma.202405002 · Cited by 46 · see citing works
A battery-free nanofluidic intracellular delivery patch for internal organs
Yin, D., Wang, P., Hao, Y., Yue, W. W., Jiang, X., Yao, K., Wang, Y., Hang, X., Xiao, A., Zhou, J., et al. (2025) · Nature · doi:10.1038/s41586-025-08943-x · Cited by 46 · see citing works
Esmailzadeh, F., Taheri‐Ledari, R., Salehi, M. M., Zarei-Shokat, S., Ganjali, F., Mohammadi, A., Zare, I., Kashtiaray, A., Jalali, F., & Maleki, A. R. (2024) · Physical Chemistry Chemical Physics · doi:10.1039/d3cp04131j · Cited by 43 · see citing works
Raheem, A., Mandal, K., Biswas, S., Ahari, A. F., Najafabadi, A. H., Farhadi, N., Zehtabi, F., Gangrade, A., Mecwan, M. M., Maity, S., et al. (2025) · Applied Physics Reviews · doi:10.1063/5.0238817 · Cited by 41 · see citing works
Recent Advances in Hydrogels for the Diagnosis and Treatment of Dry Eye Disease
Li, Q., Cao, Y., & Wang, P. (2022) · Gels · doi:10.3390/gels8120816 · Cited by 39 · see citing works
Rise of implantable drugs: A chronicle of breakthroughs in drug delivery systems
Huanbutta, K., Puri, V., Sharma, A., Singh, I., Sriamornsak, P., & Sangnim, T. (2024) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2024.102193 · Cited by 38 · see citing works
Biomimetic zwitterionic copolymerized chitosan as an articular lubricant
Deng, J., Wei, R., Qiu, H., Wu, X., Yang, Y., Huang, Z., Miao, J., Liu, A., Chai, H., Cen, X. B., et al. (2024) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2024.121821 · Cited by 33 · see citing works
Self‐Powered Electrically Controlled Drug Release Systems Based on Nanogenerator
Luo, W., Luo, R., Liu, J., Li, Z., & Wang, Y. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202311938 · Cited by 30 · see citing works
Recent Advances in Bioelectronics for Localized Drug Delivery
Jiang, X.-R., Wu, H., Xiao, A., Huang, Y., Yu, X.-G., & Chang, L.-Q. (2023) · Small Methods · doi:10.1002/smtd.202301068 · Cited by 30 · see citing works
Ultrasound Mediated Polymerization for Cell Delivery, Drug Delivery, and 3D Printing
Debbi, L., Machour, M., Dahis, D., Shoyhet, H., Shuhmaher, M., Potter, R., Tabory, Y., Goldfracht, I., Dennis, I., Blechman, T., et al. (2024) · Small Methods · doi:10.1002/smtd.202301197 · Cited by 28 · see citing works
Souri, M., Elahi, S., & Soltani, M. (2024) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2024.2323211 · Cited by 28 · see citing works
Lee, S., Park, J., Park, J., & Lee, J. Y. (2023) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.06.042 · Cited by 25 · see citing works
A reversible implantable memristor for health monitoring applications
Cao, Z., Xiang, L., Sun, B. T., Gao, K., Yu, J., Zhou, G., Duan, X., Yan, W., Lin, F., Li, Z., et al. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101096 · Cited by 24 · see citing works
Khan, A. A., & Kim, J. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116461 · Cited by 24 · see citing works
Kashkooli, F. M., Bhandari, A., Gu, B., Kolios, M. C., Kohandel, M., & Zhan, W. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.114138 · Cited by 25 · see citing works
Biochips on the Move: Emerging Trends in Wearable and Implantable Lab-on-Chip Health Monitors
Kazanskiy, N. L., Khorin, P. A., & Khonina, S. N. (2025) · Electronics · doi:10.3390/electronics14163224 · Cited by 24 · see citing works
An Implantable Magnetic Vascular Scaffold for Circulating Tumor Cell Removal In Vivo
Yin, Z., Shi, R., Xia, X., Li, L., Yang, Y., Li, S., Xu, J., Xu, Y., Cai, X., Wang, S., et al. (2022) · Advanced Materials · doi:10.1002/adma.202207870 · Cited by 25 · see citing works
Chen, Z., Guo, Z., Hu, T., Huang, B., Zheng, Q., Du, X., Huang, L., & Hu, W. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.129961 · Cited by 24 · see citing works
Recent advances in harnessing biological macromolecules for wound management: A review
Yuan, J., Wang, S., Yang, J., Schneider, K. H., Xie, M., Chen, Y., Zheng, Z., Wang, X., Zhao, Z., Yu, J., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130989 · Cited by 24 · see citing works
Antibubbles Enable Tunable Payload Release with Low‐Intensity Ultrasound
Moreno-Gómez, N., Athanassiadis, A. G., Poortinga, A. T., & Fischer, P. (2023) · Advanced Materials · doi:10.1002/adma.202305296 · Cited by 23 · see citing works
Cancer Immunotherapy Using Bioengineered Micro/Nano Structured Hydrogels
Askari, E., Barough, M. S., Rahmanian, M., Mojtabavi, N., Sarrami‐Forooshani, R., Seyfoori, A., & Akbari, M. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301174 · Cited by 22 · see citing works
Current status and challenges of shape memory scaffolds in biomedical applications
Wu, H., Yang, S., Li, J., Ma, T., Yang, K., Liao, T., Feng, W., Zhou, B., Yong, X., Zhou, K., et al. (2024) · MedComm – Biomaterials and Applications · doi:10.1002/mba2.95 · Cited by 22 · see citing works
Wirelessly controlled drug delivery systems for translational medicine
Wei, X., Wang, Y., Hu, H., Sheng, T., Yao, Y., Chen, C., Xu, G., Li, K., Su, Y., Nan, K., et al. (2025) · Nature Reviews Electrical Engineering · doi:10.1038/s44287-025-00151-z · Cited by 21 · see citing works
Ionic Diode‐Based Drug Delivery System
Yoo, H., Kang, S., Kim, J., Cho, W., Ha, H., Oh, S., Jeong, S., Lee, S., Lee, H., Park, C. S., et al. (2024) · Advanced Materials · doi:10.1002/adma.202412377 · Cited by 20 · see citing works
Chakraborty, R., Afrose, N., & Kuotsu, K. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104467 · Cited by 20 · see citing works
Insights into the innovative approaches in fiber technology for drug delivery and pharmaceuticals
Wal, P., Wal, A., Saxena, B., Mishra, S., Elossaily, G. M., Arora, R., Singh, C., Sachdeva, M., Anwer, M. K., Gulati, M., et al. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104877 · Cited by 20 · see citing works
Deng, Y., Li, Y., Chu, Z., Dai, C., & Ge, J. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02145-1 · Cited by 20 · see citing works
Injectable miniaturized shape-memory electronic device for continuous glucose monitoring
Jiang, K., Wang, H., Long, Y., Han, Y., Zhang, H., & Weng, Q. (2023) · Device · doi:10.1016/j.device.2023.100117 · Cited by 19 · see citing works
Wang, Y., Zhang, Z., Shi, Y., Yu, X., Zhang, X., Ma, X., Su, J., Ding, R., & Lin, Y. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122810 · Cited by 19 · see citing works
Nascimento, L., Richardson, G., Melo, P., & Barroca, N. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.161514 · Cited by 19 · see citing works
Meng, S., Zhang, Y., Wu, N., Peng, C., Huang, Z., Lin, Z., Cheng, Q., Liu, Z., & Kong, T. (2022) · Nano Research · doi:10.1007/s12274-022-5040-9 · Cited by 19 · see citing works
Biofunctional coatings and drug-coated stents for restenosis therapy
Wen, Y., Li, Y., Yang, R. X., Chen, Y., Shen, Y., Liu, Y., Liu, X., Zhang, B., & Li, H. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101259 · Cited by 18 · see citing works
A Wireless Implantable Closed-Loop Electrochemical Drug Delivery System
Wang, M. L., Yeon, P., Mofidfar, M., Chamberlayne, C. F., Xu, H., Annes, J. P., Zare, R. N., & Arbabian, A. (2024) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2024.3507022 · Cited by 18 · see citing works
Zhang, Y., Qi, J., Han, F., Chen, P., Li, B., Zhao, L., Bai, Z., Zhang, R., & Tao, Y. (2022) · ACS Applied Polymer Materials · doi:10.1021/acsapm.2c01506 · Cited by 18 · see citing works
Yang, F., Stahnke, R., Lawal, K., Mahnen, C. J., Duffy, P., Xu, S., & Dürig, T. (2024) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2024.124556 · Cited by 18 · see citing works
Wang, Z., Zhu, W., Li, J., Shao, Y., Li, X., Shi, H., Zhao, J., Zhou, Z., Wang, Y., & Yan, X. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c09300 · Cited by 17 · see citing works
Marengo, L. L., & Barberato-Filho, S. (2023) · Sensors · doi:10.3390/s23073597 · Cited by 16 · see citing works
Drug-eluting contact lenses: Progress, challenges, and prospects
Gao, D., Yan, C., Wang, Y., Yang, H., Liu, M., Wang, Y., Li, C., Li, C., Cheng, G., & Zhang, L. (2024) · Biointerphases · doi:10.1116/6.0003612 · Cited by 15 · see citing works
A system for bioelectronic delivery of treatment directed toward wound healing
Baniya, P., Tebyani, M., Asefifeyzabadi, N., Nguyen, T., Hernandez, C., Zhu, K., Li, H.-P., Selberg, J. A., Hsieh, H.-C., Pansodtee, P., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-41572-w · Cited by 12 · see citing works
Scholpp, S., Hoffmann, L. A., Schätzlein, E., Gries, T., Emonts, C., & Blaeser, A. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.101617 · Cited by 14 · see citing works
Wang, J., Song, N., Yin, L., Cui, Z., Wang, Y., Zhou, C., Li, J., & Qin, J. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.141826 · Cited by 13 · see citing works
External stimuli-responsive drug delivery to the posterior segment of the eye
Xu, S., Zhang, Y., Li, J., Zhang, X., & Wang, W. (2025) · Drug Delivery · doi:10.1080/10717544.2025.2476140 · Cited by 13 · see citing works
Study and Application of PZT in the Field of Wearable Devices
Xiang, W., Yin, Z., & Xue, Y. (2025) · Advanced Materials Technologies · doi:10.1002/admt.202401692 · Cited by 13 · see citing works
Responsive Microneedles for Diagnostic and Therapeutic Applications of Ocular Diseases
Mi, B., Mu, J., Ding, X., Guo, S., & Hua, X. (2025) · Small Methods · doi:10.1002/smtd.202402048 · Cited by 12 · see citing works
Yang, W., Chen, Y., Cheng, X.-L., Liu, S., Zhu, H., & Hu, Y. (2025) · Biosensors · doi:10.3390/bios15060350 · Cited by 12 · see citing works
Ear‐Area Soft Electronics for Advanced Healthcare Monitoring
Yu, Y., Zhang, H., Pan, X., Yuan, M., Sun, Y., Han, P., Fang, Q., Li, B., Xu, F., & Fang, Y. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202505046 · Cited by 10 · see citing works
Development of a wireless bioelectronic actuator for wound healing in a porcine model
Baniya, P., Tebyani, M., Hee, W. S., Li, H., Asefifeyzabadi, N., Schorger, K., Yang, H., Gallegos, A., Zhu, K., Lu, F., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-26161-3 · Cited by 10 · see citing works
Radiolabeled Risperidone microSPECT/CT Imaging for Intranasal Implant Studies Development
Simón, J. A., Utomo, E., Pareja, F., Collantes, M., Quincoces, G., Otero, A., Ecay, M., Domínguez‐Robles, J., Larrañeta, E., & Peñuelas, I. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15030843 · Cited by 10 · see citing works
Alam, S., Mohammad, O. K. J., Alfurhood, B. S., Saxena, K. K., Anand, M. V., Mahaveerakannan, R., & Savitha, V. (2023) · Multimedia Tools and Applications · doi:10.1007/s11042-023-15373-2 · Cited by 10 · see citing works
RetractedMagnetic Backscatter for In-body Communication and Localization
Tao, B., Sie, E. M. S. L., Shenoy, J., & Vasisht, D. (2023) · ACM/IEEE International Conference on Mobile Computing and Networking · doi:10.1145/3570361.3613301 · Cited by 13 · see citing works
Smart Polymer Systems: A Futuristic Approach to Enhance Therapeutic Efficacy
Seth, A. K., Parmar, G. R., Aundhia, C. J., Shah, N. V., & Gohil, D. (2024) · Current Organic Chemistry · doi:10.2174/0113852728305580240429100851 · Cited by 9 · see citing works
Li, M., Li, L., Zhang, X., Yuan, Q., Bao, B., & Tang, Y. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c20278 · Cited by 9 · see citing works
Kenchegowda, M., Angolkar, M., Hani, U., Fatease, A. M. A., Fatima, F., Talath, S., Dera, A. A., Paramshetti, S., Gangadharappa, H. V., Osmani, R. A. M., et al. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04117-8 · Cited by 9 · see citing works
Nanoparticle and Gene Therapy Strategies for Site‐Specific Pain Management: A Review
Nagaraj, K. (2025) · Advanced Therapeutics · doi:10.1002/adtp.202500356 · Cited by 10 · see citing works
Malka, R. E., Gonzales, G., Detar, W., Marinelli, L. M., Lee, C. M., Isaac, A., Miar, S., Cook, S., Guda, T., & Dion, G. R. (2023) · Laryngoscope Investigative Otolaryngology · doi:10.1002/lio2.1093 · Cited by 9 · see citing works
Recent advances in versatile cellulose-based 3D-printed drug delivery systems: A review
Wang, K., Wu, Y., Remón, J., & Ding, W. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.144433 · Cited by 8 · see citing works
Lorente, M. Á., González‐Gaitano, G., Valero, M., & González‐Benito, J. (2023) · ACS Applied Polymer Materials · doi:10.1021/acsapm.3c01109 · Cited by 8 · see citing works
Lee, S., Min, K., Jung, J., Yi, J., Tae, G., & Lee, J. Y. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.152861 · Cited by 7 · see citing works
Microwave Revolution: Transforming Biomedical Synthesis for Tissue Engineering Advancements
Sridhar, S. K., Bhavani, P. D., Noothi, S., Gajula, L. R., Prakash Goudanavar, S. O. P., Gowthami, B., & Naveen, N. R. (2024) · Current Microwave Chemistry · doi:10.2174/0122133356321729240715094501 · Cited by 7 · see citing works
Liquid metal-based biomaterials and flexible devices for injectable and implantable healthcare
Luo, Y., Yu, Y., Chen, Y., Li, R., Zhang, Y., & Chen, S. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.09.038 · Cited by 7 · see citing works
Biocompatible batteries: Powering the future of wearable and implantable medical devices
Khalid, H., Majeed, M. K., Mansoor, M. A., Aiman, V., Saleem, A., & Iqbal, R. (2026) · Journal of Energy Storage · doi:10.1016/j.est.2026.121429 · Cited by 7 · see citing works
Nanomechanical probing of bacterial adhesion to biodegradable Zn alloys
Yang, K., Wang, L., Zhang, D., Yan, Y. J., Ji, X., Cao, M., Shi, Z., & Wang, L. (2022) · Biomaterials Advances · doi:10.1016/j.bioadv.2022.213243 · Cited by 7 · see citing works
The application of biosensors in precision medicine
Brazaca, L. C., & Sempionatto, J. R. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15380-8.00006-0 · Cited by 7 · see citing works
Ebrahimnia, M., Alavi, S., Vaezi, H., Iradmousa, M. K., & Haeri, A. (2023) · EXCLI journal · doi:10.17179/excli2023-6747 · Cited by 7 · see citing works
Yang, J., Sun, B., Dai, J., Li, X., Zhao, Y., Zhang, L., Bai, J., Xue, F., & Chu, C. (2024) · Progress in Organic Coatings · doi:10.1016/j.porgcoat.2024.108577 · Cited by 7 · see citing works
Negative Pressure Smart Patch to Sense and Heal the Wound
Liu, X., Zhao, P., Wu, X., Zhao, Y., Zhou, F., Luo, Y., Jia, X., Zhong, W., Xing, M. M. Q., & Lyu, G. (2024) · Advanced Science · doi:10.1002/advs.202408077 · Cited by 7 · see citing works
Citrate-Assisted Regulation of Protein Stability and Secretability from Synthetic Amyloids
López‐Laguna, H., Favaro, M. T. D. P., Chellou-Bakkali, S., Voltà‐Durán, E., Parladé, E., Sánchez, J. M., Corchero, J. L., Unzueta, U., Villaverde, A., & Vázquez, E. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c20784 · Cited by 6 · see citing works
Treatment Considerations to Overcome the Barriers Associated with Skin Cancer Targeting
Kumari, P., Alam, A., Dhoundiyal, S., Kaur, A., & Yadav, S. (2023) · Current Cancer Therapy Reviews · doi:10.2174/0115733947253349231027043858 · Cited by 6 · see citing works
Cui, Z., Fang, H., Wei, X., He, S., & Shao, W. (2024) · ACS Applied Nano Materials · doi:10.1021/acsanm.4c05042 · Cited by 6 · see citing works
Reviews on Flexible Force Sensors Based on Fiber Assemblies with Mass Production Efficiency
Wu, L., Jin, Y., Xia, Z., Han, J., Han, W., Dong, K., Tang, Y., & Jiang, Q. (2024) · Advanced Materials Technologies · doi:10.1002/admt.202302162 · Cited by 6 · see citing works
- Authors
- Kar, A., Ahamad, N., Dewani, M., Awasthi, L., Patil, R., & Banerjee, R.
- Affiliations
- Indian Institute of Technology Bombay (IN)
- Corresponding author
- Ahamad, Nadim
- Banerjee, Rinti
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2022-04
- Volume
- 283
- Pages
- 121435
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W4214555582
- Cited by
- 179
- References
- 274
- Citations by year
- 2026: 36 · 2025: 53 · 2024: 42 · 2023: 39 · 2022: 9
- FWCI
- 3.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Biomaterials (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Education, India
- Department of Biotechnology, Ministry of Science and Technology, India
- Indian Institute of Technology Bombay (20001208)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Keywords
- implantable drug delivery, medication adherence, drug-eluting contact lenses, coronary stents, intrauterine devices, chronic disease treatment, non-invasive drug delivery
- MeSH terms
- Wearable Electronic Devices, Diabetes Mellitus, Pharmaceutical Preparations, Female, Humans, Drug Delivery Systems, Prostheses and Implants
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