In Vivo Self-Powered Wireless Cardiac Monitoring via Implantable Triboelectric Nanogenerator
Abstract
Harvesting biomechanical energy in vivo is an important route in obtaining sustainable electric energy for powering implantable medical devices. Here, we demonstrate an innovative implantable triboelectric nanogenerator (iTENG) for in vivo biomechanical energy harvesting. Driven by the heartbeat of adult swine, the output voltage and the corresponding current were improved by factors of 3.5 and 25, respectively, compared with the reported in vivo output performance of biomechanical energy conversion devices. In addition, the in vivo evaluation of the iTENG was demonstrated for over 72 h of implantation, during which the iTENG generated electricity continuously in the active animal. Due to its excellent in vivo performance, a self-powered wireless transmission system was fabricated for real-time wireless cardiac monitoring. Given its outstanding in vivo output and stability, iTENG can be applied not only to power implantable medical devices but also possibly to fabricate a self-powered, wireless healthcare monitoring system.
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An encapsulated arc-shaped implantable TENG is reported for in vivo harvesting biomechanical energy from heartbeats.
“An encapsulated arc-shaped implantable TENG (iTENG) is reported for in vivo harvesting biomechanical energy from heartbeats [Fig.2(l)].76”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [76]
Long-term stability of the iTENG is investigated by continuous output generation for over 72 h in an active animal model.
“Long-term stability of the iTENG is also investigated by continuous output generation for over 72 h in an active animal model.”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [76]
Self-powered wireless transmission of electrical signals associated with the heartbeat is successfully achieved for real-time heartbeat monitoring.
“Because of the superior in vivo performance, self-powered wireless transmission of electrical signals associated with the heartbeat is successfully achieved for realtime heartbeat monitoring.”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [76]
Driven by porcine heartbeats, the iTENG generates an open circuit voltage of 14 V and a short circuit current of 5 μA.
“Driven by porcine heartbeats, the iTENG can generate an open circuit voltage of 14 V and a short circuit current of 5 µA.”
From From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks (2019) · cites this paper as [76]
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- Authors
- Zheng, Q., Zhang, H., Shi, B., Xue, X., Liu, Z., Jin, Y., Ma, Y., Zou, Y., Wang, X., An, Z., Tang, W., Zhang, W., Yang, F., Liu, Y., Lang, X., Xu, Z., Li, Z., & Wang, Z. L.
- Affiliations
- Chinese Academy of Sciences (CN)
- Second Military Medical University (CN)
- Beihang University (CN)
- Georgia Institute of Technology (US)
- Corresponding author
- Xu, Zhiyun
- Li, Zhou
- Wang, Zhong Lin
- ORCID
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2016-06-06
- Volume
- 10
- Issue
- 7
- Pages
- 6510-6518
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W2409773124
- Cited by
- 449
- References
- 37
- Citations by year
- 2026: 19 · 2025: 47 · 2024: 51 · 2023: 44 · 2022: 63 · 2021: 68 · 2020: 48 · 2019: 44 · 2018: 42 · 2017: 19 · 2016: 4
- FWCI
- 17.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- ACS Nano (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (31571006)
- Thousands Talents Program for Pioneer Researcher and his Innovation Team
- Beijing Talents Fund (2015000021223ZK21)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Mechanical Engineering › Innovative Energy Harvesting Technologies
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Keywords
- biomechanical energy harvesting, biomedical implants, pigs, wireless power transfer
- MeSH terms
- Animals, Electricity, Electrocardiography, Heart, Monitoring, Physiologic, Electric Power Supplies, Swine, Nanotechnology
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