Versatile fluorescent probes for imaging the superoxide anion in living cells and in vivo

Oxidants, oxidative stress and the biology of ageing

Finkel, T., & Holbrook, N. J. (2000) · Nature · doi:10.1038/35041687 · Cited by 9,413 · see citing works

How mitochondria produce reactive oxygen species

Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207 · see citing works

Reactive Oxygen Species in Inflammation and Tissue Injury

Mittal, M., Siddiqui, M. R., Tran, K., Reddy, S. P., & Malik, A. B. (2014) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.5149 · Cited by 4,897 · see citing works

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

Ray, P. D., Huang, B.-W., & Tsuji, Y. (2012) · Cellular Signalling · doi:10.1016/j.cellsig.2012.01.008 · Cited by 4,373 · see citing works

ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis

D'Autréaux, B., & Toledano, M. B. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2256 · Cited by 3,642 · see citing works

Reactive oxygen species, cellular redox systems, and apoptosis

Circu, M. L., & Aw, T. Y. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.12.022 · Cited by 3,340 · see citing works

Reactive oxygen species in cell signaling

Thannickal, V. J., & Fanburg, B. L. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.279.6.l1005 · Cited by 2,936 · see citing works

Reconciling the chemistry and biology of reactive oxygen species

Winterbourn, C. C. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.85 · Cited by 2,504 · see citing works

Cellular defenses against damage from reactive oxygen species

Yu, B. (1994) · Physiological Reviews · doi:10.1152/physrev.1994.74.1.139 · Cited by 2,378 · see citing works

Signal transduction by reactive oxygen species

Finkel, T. (2011) · Journal of Cell Biology · doi:10.1083/jcb.201102095 · Cited by 2,322 · see citing works

Superoxide Ion: Generation and Chemical Implications

Hayyan, M., Hashim, M. A., & AlNashef, I. M. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00407 · Cited by 2,191 · see citing works

Cellular mechanisms and physiological consequences of redox-dependent signalling

Holmström, K. M., & Finkel, T. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3801 · Cited by 2,093 · see citing works

Fluorescence probes used for detection of reactive oxygen species

Gomes, A., Fernandes, E., & Lima, J. L. F. C. (2005) · Journal of Biochemical and Biophysical Methods · doi:10.1016/j.jbbm.2005.10.003 · Cited by 1,844 · see citing works

Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging

Yuan, L., Lin, W., Zheng, K., He, L., & Huang, W. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35313j · Cited by 1,827 · see citing works

Beyond oxidative stress: an immunologist's guide to reactive oxygen species

Nathan, C., & Cunningham-Bussel, A. (2013) · Nature Reviews Immunology · doi:10.1038/nri3423 · Cited by 1,619 · see citing works

Fluorescent and colorimetric probes for detection of thiols

Chen, X., Zhou, Y., Peng, X., & Yoon, J. (2010) · Chemical Society Reviews · doi:10.1039/b925092a · Cited by 1,580 · see citing works

Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?

Giorgio, M., Trinei, M., Migliaccio, E., & Pelicci, P. G. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2240 · Cited by 1,441 · see citing works

Reactive oxygen species: role in the development of cancer and various chronic conditions.

Waris, G., & Ahsan, H. (2006) · Journal of Carcinogenesis · doi:10.1186/1477-3163-5-14 · Cited by 1,410 · see citing works

Reactive oxygen species in cancer cells: Live by the sword, die by the sword

Schumacker, P. T. (2006) · Cancer Cell · doi:10.1016/j.ccr.2006.08.015 · Cited by 1,242 · see citing works

Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species

Chen, X., Wang, F., Hyun, J. Y., Wei, T., Qiang, J., Ren, X., Shin, I., & Yoon, J. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00192k · Cited by 1,169 · see citing works

Superoxide production by the mitochondrial respiratory chain

Turrens, J. F. (1997) · Bioscience Reports · doi:10.1023/a:1027374931887 · Cited by 903 · see citing works

Reactive oxygen species and cancer paradox: To promote or to suppress?

Galadari, S., Rahman, A. U., Pallichankandy, S., & Thayyullathil, F. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.01.004 · Cited by 895 · see citing works

Mitochondrial reactive oxygen species and cancer

Sullivan, L. B., & Chandel, N. S. (2014) · Cancer & Metabolism · doi:10.1186/2049-3002-2-17 · Cited by 799 · see citing works

Selective fluorescent imaging of superoxide <i>in vivo</i> using ethidium-based probes

Robinson, K. M., Janes, M. S., Pehar, M., Monette, J. S., Ross, M. F., Hagen, T. M., Murphy, M. P., & Beckman, J. S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601945103 · Cited by 777 · see citing works

Reactive oxygen species and the free radical theory of aging

Liochev, S. I. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.02.011 · Cited by 768 · see citing works

Extending life span by increasing oxidative stress

Ristow, M., & Schmeisser, S. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.05.010 · Cited by 718 · see citing works

Superoxide flashes in single mitochondria

Wang, W., Fang, H., Groom, L., Cheng, A., Zhang, W., Liu, J., Wang, X., Li, K., Han, P., Zheng, M., et al. (2008) · Cell · doi:10.1016/j.cell.2008.06.017 · Cited by 715 · see citing works

Exploiting the Reversible Covalent Bonding of Boronic Acids: Recognition, Sensing, and Assembly

Bull, S. D., Davidson, M. G., van den Elsen, J. M. H., Fossey, J., Jenkins, A. T. A., Jiang, Y., Kubo, Y., Marken, F., Sakurai, K., Zhao, J., et al. (2012) · Accounts of Chemical Research · doi:10.1021/ar300130w · Cited by 672 · see citing works

Combinatorial Strategies in Fluorescent Probe Development

Vendrell, M., Zhai, D., Er, J. C., & Chang, Y. (2012) · Chemical Reviews · doi:10.1021/cr200355j · Cited by 671 · see citing works

Chemiluminescence as diagnostic tool. A review

Dodeigne, C. (2000) · Talanta · doi:10.1016/s0039-9140(99)00294-5 · Cited by 563 · see citing works

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation

Brennan, A. M., Suh, S. W., Won, S. J., Narasimhan, P., Kauppinen, T. M., Lee, H., Edling, Y., Chan, P. H., & Swanson, R. A. (2009) · Nature Neuroscience · doi:10.1038/nn.2334 · Cited by 538 · see citing works

Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS)

Ristow, M., & Schmeisser, K. (2014) · Dose-Response · doi:10.2203/dose-response.13-035.ristow · Cited by 534 · see citing works

Molecular Pathways: Reactive Oxygen Species Homeostasis in Cancer Cells and Implications for Cancer Therapy

Nogueira, V., & Hay, N. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-1424 · Cited by 516 · see citing works

Superoxide production in experimental brain injury

Kontos, H. A., & Wei, E. P. (1986) · Journal of neurosurgery · doi:10.3171/jns.1986.64.5.0803 · Cited by 421 · see citing works

The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells

Winterbourn, C. C. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2013.05.004 · Cited by 420 · see citing works

Detection of superoxide generated by endothelial cells.

Rosen, G. M., & Freeman, B. Α. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.23.7269 · Cited by 402 · see citing works

Dihydrorhodamine 123: a fluorescent probe for superoxide generation?

HENDERSON, L. M., & Chappell, J. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb18328.x · Cited by 368 · see citing works

Reactive Oxygen Species in Cancer: A Dance with the Devil

Schumacker, P. T. (2015) · Cancer Cell · doi:10.1016/j.ccell.2015.01.007 · Cited by 368 · see citing works

Hydrocyanines: A class of fluorescent sensors that can image reactive oxygen species in cell culture, tissue, and in vivo

Kundu, K., Knight, S. F., Willett, N., Lee, S., Taylor, W. R., & Murthy, N. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200804851 · Cited by 339 · see citing works

Superoxide dismutase is dispensable for normal animal lifespan

Raamsdonk, J. M. V., & Hekimi, S. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1116158109 · Cited by 334 · see citing works

Mitochondrial reactive oxygen species production and elimination

Nickel, A. G., Kohlhaas, M., & Maack, C. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.03.011 · Cited by 318 · see citing works

Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo

Hu, J. J., Wong, N.-K., Ye, S., Chen, X., Lu, M.-Y., Zhao, A. Q., Guo, Y., Chun‐Hang, A., Leung, A. Y. H., Shen, J., et al. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b01881 · Cited by 280 · see citing works

When a theory of aging ages badly

Lapointe, J., & Hekimi, S. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0138-8 · Cited by 261 · see citing works

Dynamic and Reversible Fluorescence Imaging of Superoxide Anion Fluctuations in Live Cells and in Vivo

Zhang, W., Li, P., Yang, F., Hu, X., Sun, C., Zhang, W., Chen, D., & Tang, B. (2013) · Journal of the American Chemical Society · doi:10.1021/ja408524j · Cited by 232 · see citing works

Carbon-Dot-Based Ratiometric Fluorescent Probe for Imaging and Biosensing of Superoxide Anion in Live Cells

Gao, X., Ding, C., Zhu, A., & Tian, Y. (2014) · Analytical Chemistry · doi:10.1021/ac501499y · Cited by 227 · see citing works

A design of fluorescent probes for superoxide based on a nonredox mechanism

Maeda, H., Yamamoto, K., Nomura, Y., Kohno, I., Hafsi, L., Ueda, N., Yoshida, S., Fukuda, M., Fukuyasu, Y., Yamauchi, Y., et al. (2005) · Journal of the American Chemical Society · doi:10.1021/ja047018k · Cited by 196 · see citing works

Near-Infrared Fluorescence Probe for in Situ Detection of Superoxide Anion and Hydrogen Polysulfides in Mitochondrial Oxidative Stress

Huang, Y. L., Yu, F., Wang, J., & Chen, L. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b00458 · Cited by 188 · see citing works

A New Polymer Nanoprobe Based on Chemiluminescence Resonance Energy Transfer for Ultrasensitive Imaging of Intrinsic Superoxide Anion in Mice

Li, P., Liu, L., Xiao, H., Zhang, W., Wang, L., & Tang, B. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.5b11784 · Cited by 177 · see citing works

A dual response near-infrared fluorescent probe for hydrogen polysulfides and superoxide anion detection in cells and in vivo

Yu, F., Gao, M., Li, M., & Chen, L. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.06.007 · Cited by 167 · see citing works

Global Cerebral Ischemia in the Rat: Online Monitoring of Oxygen Free Radical Production Using Chemiluminescence in vivo

Dirnagl, U., Lindauer, U., Them, A., Schreiber, S., Pfister, H., Koedel, U., Reszka, R., Freyer, D., & Villringer, A. (1995) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1995.118 · Cited by 159 · see citing works

Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans

Shen, E.-Z., Song, C.-Q., Lin, Y., Zhang, W.-H., Su, P.-F., Liu, W.-Y., Zhang, P., Xu, J., Lin, N., Zhan, C., et al. (2014) · Nature · doi:10.1038/nature13012 · Cited by 139 · see citing works

Mitochondria-Targeted Reaction-Based Two-Photon Fluorescent Probe for Imaging of Superoxide Anion in Live Cells and in Vivo

Li, P., Zhang, W., Li, K., Liu, X., Xiao, H., Zhang, W., & Tang, B. (2013) · Analytical Chemistry · doi:10.1021/ac402409m · Cited by 121 · see citing works

A two-channel responsive fluorescent probe with AIE characteristics and its application for selective imaging of superoxide anions in living cells

Gao, X., Feng, G., Manghnani, P. N., Hu, F., Jiang, N., Liu, J., Liu, B., Sun, J. Z., & Tang, B. Z. (2017) · Chemical Communications · doi:10.1039/c6cc09307h · Cited by 121 · see citing works

A new endoplasmic reticulum-targeted two-photon fluorescent probe for imaging of superoxide anion in diabetic mice

Xiao, H., Liu, X., Wu, C., Wu, Y., Li, P., Guo, X., & Tang, B. (2017) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.12.068 · Cited by 117 · see citing works

A phosphinate-based near-infrared fluorescence probe for imaging the superoxide radical anion in vitro and in vivo

Zhang, J., Li, C., Zhang, R., Zhang, F., Liu, W., Liu, X., Lee, S. M., & Zhang, H. (2016) · Chemical Communications · doi:10.1039/c5cc09976e · Cited by 108 · see citing works

Selective and Sensitive Superoxide Detection with a New Diselenide-Based Molecular Probe in Living Breast Cancer Cells

Manjare, S. T., Kim, S., Heo, W. D., & Churchill, D. G. (2013) · Organic Letters · doi:10.1021/ol4033013 · Cited by 108 · see citing works

Design of a phosphinate-based fluorescent probe for superoxide detection in mouse peritoneal macrophages

Xu, K., Liu, X., Tang, B., Yang, G., Yang, Y., & An, L. (2007) · Chemistry – A European Journal · doi:10.1002/chem.200600497 · Cited by 105 · see citing works

Simultaneous Fluorescence and Chemiluminescence Turned on by Aggregation-Induced Emission for Real-Time Monitoring of Endogenous Superoxide Anion in Live Cells

Niu, J., Fan, J., Wang, X., Xiao, Y., Xie, X., Jiao, X., Sun, C., & Tang, B. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b01425 · Cited by 99 · see citing works

Development of a PET radiotracer for non-invasive imaging of the reactive oxygen species, superoxide, in vivo

Chu, W., Chepetan, A. M., Zhou, D., Shoghi, K. I., Xu, J., Dugan, L. L., Gropler, R. J., Mintun, M. A., & Mach, R. H. (2014) · Organic & Biomolecular Chemistry · doi:10.1039/c3ob42379d · Cited by 93 · see citing works

Two-photon fluorescence imaging reveals a Golgi apparatus superoxide anion-mediated hepatic ischaemia-reperfusion signalling pathway

Zhang, W., Zhang, J., Li, P., Liu, J., Su, D., & Tang, B. (2018) · Chemical Science · doi:10.1039/c8sc03917h · Cited by 91 · see citing works

Design of a practical fluorescent probe for superoxide based on protection–deprotection chemistry of fluoresceins with benzenesulfonyl protecting groups

Maeda, H., Yamamoto, K., Kohno, I., Hafsi, L., Itoh, N., Nakagawa, S., Kanagawa, N., Suzuki, K., & Uno, T. (2007) · Chemistry – A European Journal · doi:10.1002/chem.200600522 · Cited by 85 · see citing works

Mitochondria-Accessing Ratiometric Fluorescent Probe for Imaging Endogenous Superoxide Anion in Live Cells and Daphnia magna

Zhang, Z., Fan, J., Zhao, Y., Kang, Y., Du, J., & Peng, X. (2018) · ACS Sensors · doi:10.1021/acssensors.8b00082 · Cited by 83 · see citing works

A two-photon fluorescent probe for exogenous and endogenous superoxide anion imaging in vitro and in vivo

Li, R., Mao, Z., Rong, L., Wu, N. F., Lei, Q., Zhu, J., Zhuang, L., Zhang, X., & Liu, Z. (2016) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2016.08.008 · Cited by 82 · see citing works

FITC Doped Rattle-Type Silica Colloidal Particle-Based Ratiometric Fluorescent Sensor for Biosensing and Imaging of Superoxide Anion

Zhou, Y., Ding, J., Liang, T., Abdel-Halim, E. S., Jiang, L., & Zhu, J. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b01031 · Cited by 80 · see citing works

Simultaneous Fluorescence Visualization of Endoplasmic Reticulum Superoxide Anion and Polarity in Myocardial Cells and Tissue

Xiao, H., Wu, C., Li, P., & Tang, B. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.7b05440 · Cited by 79 · see citing works

Selective detection of superoxide anion radicals generated from macrophages by using a novel fluorescent probe

Gao, J. J., Xu, K. H., Tang, B., Yin, L. L., Yang, G. W., & An, L. G. (2007) · The FEBS Journal · doi:10.1111/j.1742-4658.2007.05720.x · Cited by 76 · see citing works

Mitochondria-Targeted Ratiometric Fluorescent Nanosensor for Simultaneous Biosensing and Imaging of O2•- and pH in Live Cells.

Huang, H., Dong, F., & Tian, Y. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b03470 · Cited by 73 · see citing works

A phosphinate-based red fluorescent probe for imaging the superoxide radical anion generated by RAW264. 7 macrophages

Xu, K., Liu, X., & Tang, B. (2007) · ChemBioChem · doi:10.1002/cbic.200600392 · Cited by 71 · see citing works

Te-containing carbon dots for fluorescence imaging of superoxide anion in mice during acute strenuous exercise or emotional changes

Zhang, W., Wang, R., Liu, W., Wang, X., Li, P., Zhang, W., Wang, H., & Tang, B. (2017) · Chemical Science · doi:10.1039/c7sc03878j · Cited by 71 · see citing works

Electrochemical Sensors for Direct Reagentless Measurement of Superoxide Production by Human Neutrophils

McNeil, C. J., Greenough, K. R., Weeks, P. A., Self, C. H., & Cooper, J. M. (1992) · Free Radical Research Communications · doi:10.3109/10715769209083144 · Cited by 63 · see citing works

A mitochondrion targeting fluorescent probe for imaging of intracellular superoxide radicals

Si, F., Liu, Y., Yan, K., & Zhong, W. (2015) · Chemical Communications · doi:10.1039/c5cc01075f · Cited by 61 · see citing works

Illuminating Superoxide Anion and pH Enhancements in Apoptosis of Breast Cancer Cells Induced by Mitochondrial Hyperfusion Using a New Two-Photon Fluorescence Probe

Zhang, W., Wang, X., Li, P., Xiao, H., Zhang, W., Wang, H., & Tang, B. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b01290 · Cited by 57 · see citing works

Simultaneous Determination of Superoxide and Hydrogen Peroxide in Macrophage RAW 264.7 Cell Extracts by Microchip Electrophoresis with Laser-Induced Fluorescence Detection

Li, H., Li, Q., Wang, X., Xu, K., Chen, Z., Gong, X., Liu, X., Tong, L., & Tang, B. (2009) · Analytical Chemistry · doi:10.1021/ac801777c · Cited by 55 · see citing works

Highly Fluorescent and Specific Molecular Probing of (Homo)Cysteine or Superoxide: Biothiol Detection Confirmed in Living Neuronal Cells

Murale, D. P., Kim, H., Choi, W. S., & Churchill, D. G. (2013) · Organic Letters · doi:10.1021/ol401480w · Cited by 54 · see citing works

A two-photon fluorescent probe for endogenous superoxide anion radical detection and imaging in living cells and tissues

Lu, D., Zhou, L., Wang, R., Zhang, X., He, L., Zhang, J., Hu, X., & Tan, W. (2017) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2017.04.041 · Cited by 54 · see citing works

A BODIPY-luminol chemiluminescent resonance energy-transfer (CRET) cassette for imaging of cellular superoxide

Bag, S., Tseng, J., & Rochford, J. (2014) · Organic & Biomolecular Chemistry · doi:10.1039/c4ob02413c · Cited by 51 · see citing works

A turn-on near-infrared fluorescence probe with aggregation-induced emission based on dibenzo[ a , c ]phenazine for detection of superoxide anions and its application in cell imaging

Yang, J., Liu, X., Wang, H., Tan, H., Xie, X., Zhang, X., Liu, C., Qu, X., & Hua, J. (2018) · The Analyst · doi:10.1039/c7an01860f · Cited by 51 · see citing works

Consecutive Gated Injection-Based Microchip Electrophoresis for Simultaneous Quantitation of Superoxide Anion and Nitric Oxide in Single PC-12 Cells

Li, L., Li, Q., Chen, P., Li, Z., Chen, Z., & Tang, B. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b03664 · Cited by 46 · see citing works

A highly selective and sensitive nanoprobe for detection and imaging of the superoxide anion radical in living cells

Li, N., Wang, H., Xue, M., Chang, C., Chen, Z., Zhuo, L., & Tang, B. (2012) · Chemical Communications · doi:10.1039/c2cc16376d · Cited by 44 · see citing works

A red emitting two-photon fluorescent probe for dynamic imaging of redox balance meditated by a superoxide anion and GSH in living cells and tissues

Liu, H., Zhu, X., Zhang, J., Zhang, X., & Tan, W. (2016) · The Analyst · doi:10.1039/c6an01178k · Cited by 38 · see citing works

Elucidating the relationship between superoxide anion levels and lifespan using an enhanced two-photon fluorescence imaging probe

Zhang, W., Wang, X., Li, P., Huang, F., Wang, H., Zhang, W., & Tang, B. (2015) · Chemical Communications · doi:10.1039/c5cc01670c · Cited by 37 · see citing works

ESR‐measurement of oxygen radicals in vivo after renal ischaemia in the rabbit. Effects of pre‐treatment with superoxide dismutase and heparin

NILSSON, U. A., Haraldsson, G., BRATELL, S., Sørensen, V., Åkerlund, S., Pettersson, S., Scherstén, T., & Jonsson, O. (1993) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1993.tb09498.x · Cited by 37 · see citing works

Simultaneous Determination of Reactive Oxygen and Nitrogen Species in Mitochondrial Compartments of Apoptotic HepG2 Cells and PC12 Cells Based On Microchip Electrophoresis–Laser-Induced Fluorescence

Chen, Z., Li, Q., Sun, Q., Chen, H., Wang, X., Li, N., Yin, M., Xie, Y., Li, H., & Tang, B. (2012) · Analytical Chemistry · doi:10.1021/ac300255n · Cited by 37 · see citing works

Hydrocyanines: A Class of Fluorescent Sensors That Can Image Reactive Oxygen Species in Cell Culture, Tissue, and In Vivo

Kundu, K., Knight, S. F., Willett, N. J., Lee, S., Taylor, W. R., & Murthy, N. (2008) · Angewandte Chemie · doi:10.1002/ange.200804851 · Cited by 37 · see citing works

Study and application of flow injection spectrofluorimetry with a fluorescent probe of 2-(2-pyridil)-benzothiazoline for superoxide anion radicals

Tang, B., Zhang, L., & Zhang, L. (2004) · Analytical Biochemistry · doi:10.1016/j.ab.2003.11.023 · Cited by 36 · see citing works

Simultaneous Detection of Mitochondrial Hydrogen Selenide and Superoxide Anion in HepG2 Cells under Hypoxic Conditions

Cheng, R., Kong, F., Tong, L., Liu, X., Xu, K., & Tang, B. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.8b01345 · Cited by 22 · see citing works

Rapid determination of superoxide free radical in hepatocellular carcinoma cells by MCE with LIF

Liu, X., Li, Q., Gong, X., Li, H., Chen, Z., Tong, L., & Tang, B. (2009) · Electrophoresis · doi:10.1002/elps.200800421 · Cited by 11 · see citing works

Facile sonochemical synthesis of water-soluble gold nanodots as fluorescent probes for superoxide radical anion detection and cell imaging

Li, Z., & Li, X. (2017) · Analytical Methods · doi:10.1039/c6ay03294j · Cited by 11 · see citing works

Double-ratiometric fluorescence imaging of H 2 Se and O 2 ˙ − under hypoxia for exploring Na 2 SeO 3 -induced HepG2 cells' apoptosis

Gao, X., Guo, W., Ge, L., Kong, F., Xu, K., & Tang, B. (2018) · RSC Advances · doi:10.1039/c8ra08142e · Cited by 10 · see citing works

Reaction-Based Fluorescent Probes for the Detection and Imaging of Reactive Oxygen, Nitrogen, and Sulfur Species

Wu, L., Sedgwick, A. C., Sun, X., Bull, S. D., He, X., & James, T. D. (2019) · Accounts of Chemical Research · doi:10.1021/acs.accounts.9b00302 · Cited by 669 · see citing works

Activity‐Based NIR Enzyme Fluorescent Probes for the Diagnosis of Tumors and Image‐Guided Surgery

Li, H., Kim, D., Yao, Q., Ge, H., Chung, J., Fan, J., Wang, J., Peng, X., & Yoon, J. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202009796 · Cited by 366 · see citing works

Superoxide Anion Chemistry—Its Role at the Core of the Innate Immunity

Andrés, C. M. C., Pérez de la Lastra, J. M., Andrés Juan, C., Plou, F. J., & Pérez-Lebeña, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24031841 · Cited by 342 · see citing works

Simultaneous Two-Color Visualization of Lipid Droplets and Endoplasmic Reticulum and Their Interplay by Single Fluorescent Probes in Lambda Mode

Guo, L., Tian, M., Zhang, Z., Lu, Q., Liu, Z., Niu, G., & Yu, X. (2021) · Journal of the American Chemical Society · doi:10.1021/jacs.0c12323 · Cited by 270 · see citing works

Small Molecular Fluorescent Probes for Imaging of Viscosity in Living Biosystems

Xiao, H., Li, P., & Tang, B. (2020) · Chemistry - A European Journal · doi:10.1002/chem.202004888 · Cited by 172 · see citing works

Dynamic-Reversible Photoacoustic Probe for Continuous Ratiometric Sensing and Imaging of Redox Status in Vivo

Zheng, J., Zeng, Q., Zhang, R., Xing, D., & Zhang, T. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.9b10353 · Cited by 122 · see citing works

Highly Bright AIE Nanoparticles by Regulating the Substituent of Rhodanine for Precise Early Detection of Atherosclerosis and Drug Screening

Wang, K., Gao, H., Zhang, Y., Yan, H., Si, J., Mi, X., Xia, S., Feng, X., Liu, D., Kong, D., et al. (2021) · Advanced Materials · doi:10.1002/adma.202106994 · Cited by 110 · see citing works

High-Selectivity Fluorescent Reporter toward Peroxynitrite in a Coexisting Nonalcoholic Fatty Liver and Drug-Induced Liver Diseases Model

Cheng, D., Gong, X., Wu, Q., Yuan, J., Lv, Y., Yuan, L., & Zhang, X. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c02277 · Cited by 79 · see citing works

Spatio‐Temporally Reporting Dose‐Dependent Chemotherapy via Uniting Dual‐Modal MRI/NIR Imaging

Ma, Y., Yan, C., Guo, Z., Tan, G., Niu, D., Li, Y., & Zhu, W. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202009380 · Cited by 79 · see citing works

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Li, H., Kim, D., Yao, Q., Ge, H., Chung, J., Fan, J., Wang, J., Peng, X., & Yoon, J. (2020) · Angewandte Chemie · doi:10.1002/ange.202009796 · Cited by 72 · see citing works

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Zhao, C., Chen, J., Zhong, R., Chen, D. S., Shi, J., & Song, J. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201915833 · Cited by 70 · see citing works

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Zhou, Y., Kuang, X., Yang, X., Li, J., Wei, X., Jang, W. J., Zhang, S., Yan, M., & Yoon, J. (2024) · Chemical Science · doi:10.1039/d4sc06722c · Cited by 64 · see citing works

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Zhou, L., Wang, Z., Wang, L., Zhang, X., & Xiao, Y. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.3c12181 · Cited by 41 · see citing works

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Roy, M., Niu, J., Irshad, A., Kareem, H. A., Hassan, M. U., Xu, N., Sui, X., Guo, Z., Amo, A., & Wang, Q. (2021) · Plant Stress · doi:10.1016/j.stress.2021.100044 · Cited by 39 · see citing works

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Zhang, X., Zhang, L., Cheng, X., Liu, S., Fang, S., Zhang, L., Wang, X., & Chen, L. (2022) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2022.131982 · Cited by 27 · see citing works

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Su, D., Wang, X., Zhang, W., Li, P., & Tang, B. (2021) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2021.116484 · Cited by 25 · see citing works

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Flammulina velutipes-derived carbon dots for fluorescence detection and imaging of hydroxyl radical

Hou, Y., Lin, J., Chen, Y., Jianbin, H., Su, Z., Zheng, Q., Zhao, X., Lv, X., Tang, X., & Zhou, C. (2022) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2022.122304 · Cited by 10 · see citing works

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Ding, Q., Liu, J., Zhang, X., Li, J., Wong, K. M., Sharma, A. K., Zhang, P., Fan, Q., Yin, C., Zhou, H., et al. (2025) · Chemical Science · doi:10.1039/d5sc01433f · Cited by 11 · see citing works

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Zhao, C., Chen, J., Zhong, R., Chen, D. S., Shi, J., & Song, J. (2020) · Angewandte Chemie · doi:10.1002/ange.201915833 · Cited by 9 · see citing works

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Zhang, Y., Guo, C., Du, H., Wang, X., Liu, L., & Li, C. M. (2022) · Electrochimica Acta · doi:10.1016/j.electacta.2022.141147 · Cited by 8 · see citing works

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Biomimetic liposomes as a pH/ROS cascade-responsive nanoagent with high selectivity for breast carcinoma in photothermal therapy

Wang, W., Zhang, Y., Zhang, Y., Wong, N.-K., Ma, J., Li, J., Jin, L., Wang, L., & Guan, B. (2023) · Materials & Design · doi:10.1016/j.matdes.2023.112304 · Cited by 6 · see citing works

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Mitochondria-targetable colorimetric and far-red fluorescent sensor for rapid detection of SO2 derivatives in food samples and living cells

Gong, W., Zhang, C., Zhang, X., & Shen, Y. (2022) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2022.121386 · Cited by 5 · see citing works

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Larsen, M. A., Valley, M., Karassina, N., Wang, H., Zhou, W., & Vidugirienė, J. (2024) · ACS Chemical Biology · doi:10.1021/acschembio.4c00551 · Cited by 4 · see citing works

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Li, Z., Yang, Y., Yin, P., Yang, Z., Zhang, B., Zhang, S., Han, B., Lv, J., Dong, F., & Ma, H. (2022) · ChemistrySelect · doi:10.1002/slct.202104525 · Cited by 3 · see citing works

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Zhu, L., Yan, T., Alimu, G., Zhang, L., Ma, R., Alifu, N., Zhang, X., & Wang, D. (2022) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2022.3332 · Cited by 2 · see citing works

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Wang, K., Jiao, Y., Ma, Q., Shu, W., Xiao, H., Zhang, T., & Liu, Y. (2022) · ChemistrySelect · doi:10.1002/slct.202202756 · Cited by 2 · see citing works

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Li, D., Tang, F., Wen, K., Yang, Z., Xiao, H., & Zhou, Z. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3955747

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Lu, D., Zhou, L., Wang, R., Zhang, X., He, L., Zhang, J., Hu, X., & Tan, W. (2017) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2017.04.041 · Cited by 54 · see citing works

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Zhang, N., He, Y., Tang, Q. H., Wang, Y., Zheng, Q., & Hu, P. P. (2018) · Talanta · doi:10.1016/j.talanta.2018.09.109 · Cited by 25 · see citing works

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