Cited by 128Algal biology and biofuel productionFluid Dynamics and MixingMicrobial Metabolic Engineering and Bioproduction

Photobioreactor cultivation strategies for microalgae and cyanobacteria

Johnson, Tylor J., Katuwal, Sarmila, Anderson, Gary A., Gu, Liping, Zhou, Ruanbao, Gibbons, William R.·2018·Biotechnology Progress

Abstract

The current burden on fossil-derived chemicals and fuels combined with the rapidly increasing global population has led to a crucial need to develop renewable and sustainable sources of chemicals and biofuels. Photoautotrophic microorganisms, including cyanobacteria and microalgae, have garnered a great deal of attention for their capability to produce these chemicals from carbon dioxide, mineralized water, and solar energy. While there have been substantial amounts of research directed at scaling-up production from these microorganisms, several factors have proven difficult to overcome, including high costs associated with cultivation, photobioreactor construction, and artificial lighting. Decreasing these costs will substantially increase the economic feasibility of these production processes. Thus, the purpose of this review is to describe various photobioreactor designs, and then provide an overview on lighting systems, mixing, gas transfer, and the hydrodynamics of bubbles. These factors must be considered when the goal of a production process is economic feasibility. Targets for improving microalgae and cyanobacteria cultivation media, including water reduction strategies will also be described. As fossil fuel reserves continue to be depleted and the world population continues to increase, it is imperative that renewable chemical and biofuel production processes be developed toward becoming economically feasible. Thus, it is essential that future research is directed toward improving these processes. © 2018 American Institute of Chemical Engineers Biotechnol. Prog., 34:811-827, 2018.

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Crossref · 10.1002/btpr.2628

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201 of 201 references verified0 citation errors · 0 not checkable

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  • Mixing is important for the convective transport of dissolved gases and nutrients in order to prevent limitations in the culture broth.

    “Mixing is not only important for the homogeneous distribution of the cells but also for the convective transport of dissolved gases and nutrients in order to prevent limitations in the culture broth [107].”

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Authors
Johnson, T. J., Katuwal, S., Anderson, G. A., Gu, L., Zhou, R., & Gibbons, W. R.
Affiliations
South Dakota State University (US)
Corresponding author
  • Johnson, Tylor J.
  • Zhou, Ruanbao
Venue
Biotechnology Progress
Publisher
Wiley
Published
2018-03-23
Volume
34
Issue
4
Pages
811-827
ISSN
  • 1520-6033 (ISSN-L)
  • 8756-7938
OpenAlex
W2791882155
Cited by
128
References
201
Citations by year
2026: 20 · 2025: 16 · 2024: 15 · 2023: 17 · 2022: 12 · 2021: 23 · 2020: 14 · 2019: 8 · 2018: 3
FWCI
0.64
Type
journal article
Language
en
Open access
closed
Locations
  • Biotechnology Progress (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • South Dakota Agricultural Experiment Station (SD00H398‐11)
  • National Aeronautics and Space Administration (NNX11AM03A)
  • NSF
  • USDA (11665597)
Topics
  • Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
  • Physical Sciences › Engineering › Biomedical Engineering › Fluid Dynamics and Mixing
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
Keywords
photobioreactor design, microalgae cultivation, cyanobacteria cultivation, biofuels, renewable chemicals, lighting systems, mixing, gas transfer, bubble hydrodynamics, cultivation media, water reduction, economic feasibility, scale-up
MeSH terms
Cyanobacteria, Sunlight, Microalgae, Photobioreactors

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