Frontal lobe and posterior parietal contributions to the cortico-cerebellar system

Ramnani, Narender

doi:10.1007/s12311-011-0272-3

Cited by 156Motor Control and AdaptationVestibular and auditory disordersNeural and Behavioral Psychology Studies

Frontal lobe and posterior parietal contributions to the cortico-cerebellar system

Ramnani, Narender·2012·The Cerebellum

DOI 10.1007/s12311-011-0272-3

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Abstract

Our growing understanding of how cerebral cortical areas communicate with the cerebellum in primates has enriched our understanding of the data that cerebellar circuits can access, and the neocortical areas that cerebellar activity can influence. The cerebellum is part of some large-scale networks involving several parts of the neocortex including association areas in the frontal lobe and the posterior parietal cortex that are known for their contributions to higher cognitive function. Understanding their connections with the cerebellum informs the debates around the role of the cerebellum in higher cognitive functions because they provide mechanisms through which association areas and the cerebellum can influence each others' operations. In recent years, evidence from connectional anatomy and human neuroimaging have comprehensively overturned the view that the cerebellum contributes only to motor control. The aim of this review is to examine our changing perspectives on the nature of cortico-cerebellar anatomy and the ways in which it continues to shape our views on its contributions to function. The review considers the anatomical connectivity of the cerebellar cortex with frontal lobe areas and the posterior parietal cortex. It will first focus on the anatomical organisation of these circuits in non-human primates before discussing new findings about this system in the human brain. It has been suggested that in non-human primates "although there is a modest input from medial prefrontal cortex, there is very little or none from the more lateral prefrontal areas" [33]. This review discusses anatomical investigations that challenge this claim. It also attempts to dispel the misconception that prefrontal projections to the cerebellum are from areas concerned only with the kinematic control of eye movements. Finally, I argue that our revised understanding of anatomy compels us to reconsider conventional views of how these systems operate in the human brain.

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Both the basal ganglia and the cerebellum receive direct input from the motor cortex and are involved in the preparation, learning, and sensorimotor coordination of movements.
“because both brain structures receive direct input from the motor cortex and are involved in the preparation, learning, and sensorimotor coordination of movements.”
From Neandertal Introgression Sheds Light on Modern Human Endocranial Globularity (2019) · cites this paper as [38]

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Authors: Ramnani, N.
Affiliations: University of London (GB)
Corresponding author: Ramnani, Narender
ORCID: Ramnani, Narender
Venue: The Cerebellum
Publisher: Springer Science and Business Media LLC
Published: 2011-06-14
Volume: 11
Issue: 2
Pages: 366-383
ISSN: 1473-4222 (ISSN-L)
1473-4230
DOI: 10.1007/s12311-011-0272-3
OpenAlex: W1988468568
Cited by: 156
References: 104
Citations by year: 2026: 11 · 2025: 12 · 2024: 13 · 2023: 10 · 2022: 10 · 2021: 13 · 2020: 4 · 2019: 12 · 2018: 13 · 2017: 9 · 2016: 11 · 2015: 9 · 2014: 11 · 2013: 12 · 2012: 5
FWCI: 0.79
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: The Cerebellum (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords: cerebellum, frontal lobe, posterior parietal cortex, prefrontal cortex, association cortex, non-human primates, human brain, cerebellar circuits, higher mental functions, oculomotor control
MeSH terms: Animals, Cerebellum, Cerebral Cortex, Biological Evolution, Frontal Lobe, Humans, Motor Cortex, Neural Pathways, Oxygen, Parietal Lobe, Primates

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Frontal lobe and posterior parietal contributions to the cortico-cerebellar system

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