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The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta
Open accessAbstract
Prior studies revealed that aversive stimuli and psychostimulant drugs elicit Fos expression in neurons clustered above and behind the interpeduncular nucleus that project strongly to the ventral tegmental area (VTA) and substantia nigra (SN) compacta (C). Other reports suggest that these neurons modulate responses to aversive stimuli. We now designate the region containing them as the "mesopontine rostromedial tegmental nucleus" (RMTg) and report herein on its neuroanatomy. Dense micro-opioid receptor and somatostatin immunoreactivity characterize the RMTg, as do neurons projecting to the VTA/SNC that are enriched in GAD67 mRNA. Strong inputs to the RMTg arise in the lateral habenula (LHb) and, to a lesser extent, the SN. Other inputs come from the frontal cortex, ventral striatopallidum, extended amygdala, septum, preoptic region, lateral, paraventricular and posterior hypothalamus, zona incerta, periaqueductal gray, intermediate layers of the contralateral superior colliculus, dorsal raphe, mesencephalic, pontine and medullary reticular formation, and the following nuclei: parafascicular, supramammillary, mammillary, ventral lateral geniculate, deep mesencephalic, red, pedunculopontine and laterodorsal tegmental, cuneiform, parabrachial, and deep cerebellar. The RMTg has meager outputs to the forebrain, mainly to the ventral pallidum, preoptic-lateral hypothalamic continuum, and midline-intralaminar thalamus, but much heavier outputs to the brainstem, including, most prominently, the VTA/SNC, as noted above, and to medial tegmentum, pedunculopontine and laterodorsal tegmental nuclei, dorsal raphe, and locus ceruleus and subceruleus. The RMTg may integrate multiple forebrain and brainstem inputs in relation to a dominant LHb input. Its outputs to neuromodulatory projection systems likely converge with direct LHb projections to those structures.
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“It was shown that the LHb has an inhibitory influence on dopaminergic neurons (Matsumoto and Hikosaka, 2007) via GABAergic interneurons in the rostromedial tegmental nucleus (Ji and Shepard, 2007; Jhou et al., 2009), which is reflected by the fact that lesioning of the habenula leads to an increase of cortical and striatal dopamine levels (Nishikawa et al., 1986).”
From Circuit Mechanisms of Reward, Anhedonia, and Depression (2019) · cites this paper as Jhou et al., 2009
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Citations
Cites
Brain stem reticular formation and activation of the EEG
Moruzzi, G., & Magoun, H. W. (1949) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(49)90219-9 · Cited by 4,307
Hypothalamic regulation of sleep and circadian rhythms
Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804
Large-scale neurocognitive networks and distributed processing for attention, language, and memory
Mesulam, M. (1990) · Annals of Neurology · doi:10.1002/ana.410280502 · Cited by 2,684
Aston-Jones, G., & Bloom, F. (1981) · The Journal of Neuroscience · doi:10.1523/jneurosci.01-08-00876.1981 · Cited by 1,960
Histochemical mapping of nitric oxide synthase in the rat brain
Vincent, S. R., & Kimura, H. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90184-4 · Cited by 1,868
Mapping Patterns of c- fos Expression in the Central Nervous System After Seizure
Morgan, J. I., Cohén, D., Hempstead, J. L., & Curran, T. (1987) · Science · doi:10.1126/science.3037702 · Cited by 1,786
Pan, L., Gurevich, E. V., & Gurevich, V. V. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209532200 · Cited by 1,758
Swanson, L. W. (1982) · Brain Research Bulletin · doi:10.1016/0361-9230(82)90145-9 · Cited by 1,718 · cited 1×
“…raphe nuclei (Andén et al., 1964, 1965, 1966; Fallon et al., 1978; Fallon and Moore, 1978; Lindvall and Björklund, 1983; Björklund and Lindvall, 1984; Swanson, 1982; Deutch et al., 1988; Hallanger and Wainer, 1988; Cornwall et al., 1990; Vertes, 1991; Gritti et al., 1997, 2003; Vertes et al.,…”
Differential expression of orexin receptors 1 and 2 in the rat brain
Marcus, J. N., Aschkenasi, C. J., Lee, C. E., Chemelli, R. M., Saper, C. B., Yanagisawa, M., & Elmquist, J. K. (2001) · Journal of Comparative Neurology · doi:10.1002/cne.1190 · Cited by 1,659
The sleep switch: hypothalamic control of sleep and wakefulness
Saper, C. B., Chou, T. C., & Scammell, T. E. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)02002-6 · Cited by 1,656
Emson, P. C., Heffher, R. R., & Pearson, J. (1984) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-198409000-00010 · Cited by 1,651
Ikemoto, S. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.05.004 · Cited by 1,477
Bredt, D. S., Glatt, C. E., Hwang, P. M., Fotuhi, M., Dawson, T. M., & Snyder, S. H. (1991) · Neuron · doi:10.1016/0896-6273(91)90374-9 · Cited by 1,359
Lateral habenula as a source of negative reward signals in dopamine neurons
Matsumoto, M., & Hikosaka, O. (2007) · Nature · doi:10.1038/nature05860 · Cited by 1,292
A putative flip–flop switch for control of REM sleep
Lu, J., Sherman, D. L., Devor, M. G., & Saper, C. B. (2006) · Nature · doi:10.1038/nature04767 · Cited by 1,265
Specificity in the projection patterns of accumbal core and shell in the rat
Heimer, L., Zahm, D. S., Churchill, L., Kalivas, P. W., & Wohltmann, C. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90202-y · Cited by 1,219
Alheid, G. F., & Heimer, L. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90217-5 · Cited by 1,217
Ascending Monoamine Neurons to the Telencephalon and Diencephalon
Andén, N. ‐., Dahlström, A. B., Fuxé, K., Larsson, K., Olson, L., & Ungerstedt, U. (1966) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1966.tb03318.x · Cited by 1,214
Two genes encode distinct glutamate decarboxylases
Erlander, M. G., Tillakaratne, N. J. K., Feldblum, S., Patel, N., & Tobin, A. J. (1991) · Neuron · doi:10.1016/0896-6273(91)90077-d · Cited by 1,213
Fallon, J. H., & Moore, R. Y. (1978) · The Journal of Comparative Neurology · doi:10.1002/cne.901800310 · Cited by 1,190
Brog, J. S., Salyapongse, A., Deutch, A. Y., & Zahm, D. S. (1993) · Journal of Comparative Neurology · doi:10.1002/cne.903380209 · Cited by 1,102
Role of ion flux in the control of c-fos expression
Morgan, J. I., & Curran, T. (1986) · Nature · doi:10.1038/322552a0 · Cited by 998
Van der Werf, Y. D., Witter, M. P., & Groenewegen, H. J. (2002) · Brain Research Reviews · doi:10.1016/s0165-0173(02)00181-9 · Cited by 994
Simmons, D. M., Arriza, J. L., & Swanson, L. W. (1989) · Journal of Histotechnology · doi:10.1179/his.1989.12.3.169 · Cited by 921
Handbook of chemical neuroanatomy
(2005) · Handbook of chemical neuroanatomy · doi:10.1016/s0924-8196(05)80001-6 · Cited by 906
Kelley, A. E., Domesick, V. B., & Nauta, W. J. H. (1982) · Neuroscience · doi:10.1016/0306-4522(82)90067-7 · Cited by 888
Fluoro-gold: a new fluorescent retrograde axonal tracer with numerous unique properties
Schmued, L. C., & Fallon, J. H. (1986) · Brain Research · doi:10.1016/0006-8993(86)91199-6 · Cited by 887
Ferrier, D. (1876) · G P Putnam's Sons eBooks · doi:10.1037/12860-000 · Cited by 872
Amygdaloid projections to the mesencephalon, pons and medulla oblongata in the cat
Hopkins, D. A., & Holstege, G. (1978) · Experimental Brain Research · doi:10.1007/bf00239551 · Cited by 866
Efferent connections of the habenular nuclei in the rat
Herkenham, M. A., & Nauta, W. J. H. (1979) · The Journal of Comparative Neurology · doi:10.1002/cne.901870103 · Cited by 855
A PHA-L analysis of ascending projections of the dorsal raphe nucleus in the rat
Vertes, R. P. (1991) · Journal of Comparative Neurology · doi:10.1002/cne.903130409 · Cited by 842 · cited 1×
“…nuclei (Andén et al., 1964, 1965, 1966; Fallon et al., 1978; Fallon and Moore, 1978; Lindvall and Björklund, 1983; Björklund and Lindvall, 1984; Swanson, 1982; Deutch et al., 1988; Hallanger and Wainer, 1988; Cornwall et al., 1990; Vertes, 1991; Gritti et al., 1997, 2003; Vertes et al., 1999).”
Demonstration and mapping out of nigro-neostriatal dopamine neurons
Andén, N. ‐., Carlsson, A., Dahlström, A. B., Fuxé, K., Hillarp, N. ‐., & Larsson, K. (1964) · Life Sciences · doi:10.1016/0024-3205(64)90161-4 · Cited by 812
Herkenham, M. A., & Nauta, W. J. H. (1977) · The Journal of Comparative Neurology · doi:10.1002/cne.901730107 · Cited by 798
Uniform Inhibition of Dopamine Neurons in the Ventral Tegmental Area by Aversive Stimuli
Ungless, M. A., Magill, P. J., & Bolam, J. P. (2004) · Science · doi:10.1126/science.1093360 · Cited by 782
Johansson, O., Hökfelt, T., & Elde, R. P. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90233-1 · Cited by 674
Hope, B. T., Nye, H. E., Kelz, M. B., Self, D. W., Iadarola, M. J., Nakabeppu, Y., Duman, R. S., & Nestler, E. J. (1994) · Neuron · doi:10.1016/0896-6273(94)90061-2 · Cited by 562
Rye, D. B., Saper, C. B., Lee, H. J., & Wainer, B. H. (1987) · The Journal of Comparative Neurology · doi:10.1002/cne.902590403 · Cited by 545
Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology
Aston‐Jones, G., Shipley, M., Chouvet, G., Ennis, M. J., Bockstaele, E. V., Pieribone, V. A., Shiekhattar, R., Akaoka, H., Drolet, G., Astier, B., et al. (1991) · Progress in brain research · doi:10.1016/s0079-6123(08)63799-1 · Cited by 543
Fallon, J. H., Koziell, D. A., & Moore, R. Y. (1978) · The Journal of Comparative Neurology · doi:10.1002/cne.901800308 · Cited by 501
Glutamatergic Afferents of the Ventral Tegmental Area in the Rat
Geisler, S., Derst, C., Veh, R. W., & Zahm, D. S. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0012-07.2007 · Cited by 486
Hypothalamic Arousal Regions Are Activated during Modafinil-Induced Wakefulness
Scammell, T. E., Estabrooke, I. V., McCarthy, M. T., Chemelli, R. M., Yanagisawa, M., Miller, M. S., & Saper, C. B. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-22-08620.2000 · Cited by 484
Curran, T., & Morgan, J. I. (1985) · Science · doi:10.1126/science.4035354 · Cited by 479
Christoph, G., Leonzio, R., & Wilcox, K. (1986) · The Journal of Neuroscience · doi:10.1523/jneurosci.06-03-00613.1986 · Cited by 418
Locus coeruleus and regulation of behavioral flexibility and attention
(2000) · Progress in Brain Research · doi:10.1016/s0079-6123(00)26013-5 · Cited by 400
Ji, H., & Shepard, P. D. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0958-07.2007 · Cited by 388
Afferents of the ventral tegmental area in the rat-anatomical substratum for integrative functions
Geisler, S., & Zahm, D. S. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20668 · Cited by 379
Self-citationChapter 1 The emotional motor system
Holstege, G., Bandler, R., & Saper, C. B. (1996) · Progress in Brain Research · doi:10.1016/s0079-6123(08)61855-5 · Cited by 379
Localization of nitric oxide synthase in the adult rat brain
Rodrigo, J., Springall, D. R., UTTENTHAL, L. O., Bentura, M. L., Abadía‐Molina, F., Riveros‐Moreno, V., Martínez‐Murillo, R., Polak, J. M., & Moncada, S. (1994) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1994.0096 · Cited by 378
Harrington, M. E. (1997) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(96)00019-x · Cited by 367
Hallanger, A. E., & Wainer, B. H. (1988) · The Journal of Comparative Neurology · doi:10.1002/cne.902740403 · Cited by 343
The pedunculopontine tegmental nucleus: Where the striatum meets the reticular formation
Inglis, W. L., & Winn, P. (1995) · Progress in Neurobiology · doi:10.1016/0301-0082(95)00013-l · Cited by 337
Chapter 14 Descending motor pathways and the spinal motor system: Limbic and non-limbic components
Holstege, G. (1991) · Progress in brain research · doi:10.1016/s0079-6123(08)63057-5 · Cited by 323
Gritti, I., Mainville, L., Mancia, M., & Jones, B. E. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970630)383:2 · Cited by 312
Afferent and efferent connections of the laterodorsal tegmental nucleus in the rat
Cornwall, J., Cooper, J. D., & Phillipson, O. T. (1990) · Brain Research Bulletin · doi:10.1016/0361-9230(90)90072-8 · Cited by 300
Steininger, T. L., Rye, D. B., & Wainer, B. H. (1992) · The Journal of Comparative Neurology · doi:10.1002/cne.903210403 · Cited by 273
Kayama, Y., Ohta, M., & Jodo, E. (1992) · Brain Research · doi:10.1016/0006-8993(92)90632-j · Cited by 247
Afferent connections of the zona incerta: A horseradish peroxidase study in the rat
Shammah‐Lagnado, S. J., Negrão, N., & Ricardo, J. A. (1985) · Neuroscience · doi:10.1016/0306-4522(85)90127-7 · Cited by 209
Telencephalic Projections of the A8 Dopamine Cell Group
Deutch, A. Y., Goldstein, M., Baldino, F., & Roth, R. H. (1988) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1988.tb42095.x · Cited by 205
Perrotti, L. I., Bolaños, C. A., Choi, K., Russo, S. J., Edwards, S., Ulery, P. G., Wallace, D. L., Self, D. W., Nestler, E. J., & Barrot, M. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04110.x · Cited by 178 · cited 3×
“D and shown in several previous publications following various experimental treatments (Scammell et al., 2000; Perrotti et al., 2005; Geisler et al., 2008).”
BackgroundAndén, N., Dahlström, A. B., Fuxé, K., & Larsson, K. (1965) · Life Sciences · doi:10.1016/0024-3205(65)90076-7 · Cited by 178
Gritti, I., Manns, I. D., Mainville, L., & Jones, B. E. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10505 · Cited by 178
Devor, M. G., & Zalkind, V. I. (2001) · Pain · doi:10.1016/s0304-3959(01)00345-1 · Cited by 176
Topographical organization of GABAergic neurons within the ventral tegmental area of the rat
Olson, V. G., & Nestler, E. J. (2006) · Synapse · doi:10.1002/syn.20345 · Cited by 170
Araki, M., McGeer, P. L., & Kimura, H. (1988) · Brain Research · doi:10.1016/0006-8993(88)91410-2 · Cited by 163
Metabolic mapping with cellular resolution: c-fos vs. 2-deoxyglucose.
Sharp, F. R., Sagar, S. M., & Swanson, R. A. (1993) · PubMed · Cited by 157
The Lateral Habenula:No Longer Neglected
Geisler, S., & Trimble, M. (2008) · CNS Spectrums · doi:10.1017/s1092852900016710 · Cited by 155
Shepard, D. S., Holcomb, H. H., & Gold, J. M. (2005) · Schizophrenia Bulletin · doi:10.1093/schbul/sbj083 · Cited by 140
Shammah‐Lagnado, S. J., Costa, M. S. M. O., & Ricardo, J. A. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90433-3 · Cited by 138
The evolving theory of basal forebrain functional—anatomical ‘macrosystems’
Zahm, D. S. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.06.003 · Cited by 130
Direct comparison of projections from the central amygdaloid region and nucleus accumbens shell
Zahm, D. S., Jensen, S. L., Williams, E. S., & Martin, J. R. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00524.x · Cited by 121
(1996) · Progress in brain research · doi:10.1016/s0079-6123(08)x6058-3 · Cited by 121
Wu, M. ‐., John, J., Boehmer, L. N., Yau, D. M., Nguyen, G. B., & Siegel, J. M. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.052134 · Cited by 120
Chapter 28 Theories of basal forebrain organization and the “emotional motor system”
Alheid, G. F., & Heimer, L. (1996) · Progress in brain research · doi:10.1016/s0079-6123(08)61882-8 · Cited by 115
Evidence that Fluoro-Gold can be transported avidly through fibers of passage
Dado, R. J., Burstein, R., Cliffer, K. D., & Giesler, G. J. (1990) · Brain Research · doi:10.1016/0006-8993(90)91358-n · Cited by 112
Ferreira, J. G. P., Del-Fava, F., Hasue, R. H., & Shammah‐Lagnado, S. J. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.02.003 · Cited by 110
The iontophoretic application of Fluoro-Gold for the study of afferents to deep brain nuclei
Pieribone, V. A., & Aston‐Jones, G. (1988) · Brain Research · doi:10.1016/0006-8993(88)90614-2 · Cited by 109
THE RÔLE OF THE HYPOTHALAMUS AND MESENCEPHALON IN LOCOMOTION
Hinsey, J. C. (1930) · Archives of Neurology And Psychiatry · doi:10.1001/archneurpsyc.1930.02220070004001 · Cited by 105
Holstege, G., Mouton, L. J., & Gerrits, P. O. (2004) · Elsevier eBooks · doi:10.1016/b978-012547626-3/50037-5 · Cited by 104
Carbachol models of REM sleep: recent developments and new directions.
Kubin, L. K. (2001) · PubMed · Cited by 101
Coizet, V., Dommett, E. J., Redgrave, P., & Overton, P. G. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.01.030 · Cited by 92
Geisler, S., & Zahm, D. S. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04928.x · Cited by 90
Prominent Activation of Brainstem and Pallidal Afferents of the Ventral Tegmental Area by Cocaine
Geisler, S., Marinelli, M., DeGarmo, B., Becker, M. L., Freiman, A. J., Beales, M., Meredith, G. E., & Zahm, D. S. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301650 · Cited by 87
Schulz, S., Schreff, M., Koch, T., Zimprich, A. A., Gramsch, C., Elde, R., & Höllt, V. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00288-1 · Cited by 83
Sukhotinsky, I., Zalkind, V. I., Lu, J., Hopkins, D. A., Saper, C. B., & Devor, M. G. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05399.x · Cited by 82
Iontophoretic injection of fluoro-gold and other fluorescent tracers.
Schmued, L. C., & Heimer, L. (1990) · Journal of Histochemistry & Cytochemistry · doi:10.1177/38.5.2332627 · Cited by 80
Colussi‐Mas, J., Geisler, S., Zimmer, L., Zahm, D. S., & Bérod, A. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05738.x · Cited by 68
The Behaviour of Chronically Decerebrate Cats
Bard, P., & Macht, M. B. (1958) · Novartis Foundation symposium · doi:10.1002/9780470719091.ch4 · Cited by 61
Kowski, A. B., Geisler, S., Krauss, M. I., & Veh, R. W. (2008) · The Journal of Comparative Neurology · doi:10.1002/cne.21610 · Cited by 58
Cellular-resolution activity mapping of the brain using immediate-early gene expression
Farivar, R. (2004) · Frontiers in bioscience · doi:10.2741/1198 · Cited by 58
Riveros‐Moreno, V., Beddell, C. R., & Moncada, S. (1993) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1993.tb18095.x · Cited by 53
Mu�oz, A., Woods, T. M., & Jones, E. G. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990517)407:4 · Cited by 52
Neural mechanisms of freezing and passive aversive behaviors
Jhou, T. (2005) · The Journal of comparative neurology · doi:10.1002/cne.20734 · Cited by 51
Shammah‐Lagnado, S. J., Ricardo, J. A., Sakamoto, N., & ̃o, N. N. (1983) · Neuroscience · doi:10.1016/0306-4522(83)90302-0 · Cited by 45
Sukhotinsky, I., Hopkins, D. A., Lu, J., Saper, C. B., & Devor, M. G. (2005) · The Journal of Comparative Neurology · doi:10.1002/cne.20636 · Cited by 43
Reynolds, S. M., Geisler, S., Bérod, A., & Zahm, D. S. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04791.x · Cited by 31
Wirtshafter, D., Klitenick, M. A., & Asin, K. E. (1988) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(88)90068-8 · Cited by 30
Voss, L. J., Young, B. J., Barnard, J. P. M., & Sleigh, J. W. (2005) · Anaesthesia and Intensive Care · doi:10.1177/0310057x0503300313 · Cited by 28
Arts, M. P. M., Groenewegen, H. J., Veening, J. G., & Cools, A. R. (1996) · Brain Research Bulletin · doi:10.1016/0361-9230(96)00048-2 · Cited by 26
Harris, G. W. (1958) · Novartis Foundation symposium · doi:10.1002/9780470719091.ch1 · Cited by 5
Zahm (1996) · doi:10.1002/(sici)1096-9861(19960108)364:2
Research works printed but not linked: 2
- Heimer L, 2008, Anatomy of neuropsychiatry: the new anatomy of the basal forebrain and its implications for neuropsychiatric disease
- Jakab RL, 1995, The rat nervous system, 405
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Metadata
- Authors
- Jhou, T. C., Geisler, S., Marinelli, M., Degarmo, B. A., & Zahm, D. S.
- Affiliations
- National Institutes of Health (US)
- Saint Louis University (US)
- Rosalind Franklin University of Medicine and Science (US)
- Corresponding author
- Jhou, Thomas C.
- Zahm, Daniel S.
- Venue
- Journal of Comparative Neurology
- Publisher
- Wiley
- Published
- 2009-02-20
- Volume
- 513
- Issue
- 6
- Pages
- 566-596
- ISSN
- 0021-9967 (ISSN-L)
- 1096-9861
- PMC
- PMC3116663
- OpenAlex
- W2085520758
- Cited by
- 503
- References
- 102
- Citations by year
- 2026: 16 · 2025: 15 · 2024: 35 · 2023: 13 · 2022: 17 · 2021: 39 · 2020: 48 · 2019: 39 · 2018: 34 · 2017: 27 · 2016: 34 · 2015: 26 · 2014: 38 · 2013: 36 · 2012: 28
- FWCI
- 11.61
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Journal of Comparative Neurology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (HL 60292, P50HL060292)
- National Institute of Mental Health (MH-12370, F31MH012370)
- National Institute on Drug Abuse (DA020654, R01DA020654)
- National Institute of Neurological Disorders and Stroke (NS23805, R01NS023805)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Keywords
- rostromedial tegmental nucleus, lateral habenula, ventral tegmental area, substantia nigra pars compacta, mesopontine tegmentum, interpeduncular nucleus, Fos expression, aversive stimuli, psychostimulants, mu-opioid receptor, somatostatin, GAD67, neuroanatomy, brainstem projections, neuromodulation, pedunculopontine nucleus, laterodorsal tegmentum, dorsal raphe nucleus, locus coeruleus
- MeSH terms
- Animals, Cocaine, Glutamate Decarboxylase, Male, Methamphetamine, Neural Pathways, RNA, Messenger, Self Administration, Somatostatin, Substantia Nigra, Sulfur Radioisotopes, Tegmentum Mesencephali, Gene Expression, Proto-Oncogene Proteins c-fos, Rats, Sprague-Dawley, Receptors, Opioid, mu, Ventral Tegmental Area, Habenula, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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