Cited by 213Digital Mental Health InterventionsPosttraumatic Stress Disorder ResearchSleep and related disorders

EFFECTIVENESS OF INTERNET-DELIVERED COGNITIVE BEHAVIORAL THERAPY FOR POSTTRAUMATIC STRESS DISORDER: A SYSTEMATIC REVIEW AND META-ANALYSIS: Review: Internet-Delivered CBT for PTSD

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Sijbrandij, Marit, Kunovski, Ivo, Cuijpers, Pim·2016·Depression and Anxiety

Abstract

BACKGROUND: Internet-delivered cognitive behavioral therapy (iCBT) is a relatively novel treatment method that may improve the accessibility of mental health care for individuals with posttraumatic stress disorder (PTSD). The aim of this meta-analysis was to evaluate the effectiveness of iCBT compared to inactive (waitlist control and treatment-as-usual (TAU)) and active other interventions in reducing PTSD symptoms. METHODS: A meta-analysis of 12 randomized controlled trials (14 comparisons) and 1,306 participants was conducted. RESULTS: The pooled effect size of the 11 comparisons (10 studies, 1,139 participants) that compared iCBT to waitlist and TAU control was moderate (g = 0.71, 95% CI [0.49-0.93], P < .001), and showed moderate heterogeneity. The pooled effect size of the three studies (three comparisons) comparing iCBT to other interventions was small (g = 0.28, 95% CI [-0.00 to 0.56], P = .05), with low heterogeneity. CONCLUSION: The findings of this systematic review and meta-analysis show that iCBT is an effective treatment for individuals with PTSD and comorbid depressive symptoms. However, further research is needed for effective dissemination of iCBT in clinical practice.

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  1. [12]12. Depression and Anxiety 15206394, 2016, 9, Downloaded from https://onlinelibrary.wiley.com/doi/10.1002/da.22533 by Mount Vernon Nazarene University, Wiley Online Library on [03/09/2026]. See the Terms and Conditions (https://onlinelibrary.wiley.com/terms-and-conditions) on Wiley Online Library for rules of use; OA articles are governed by the applicable Creative Commons License
  2. [38]38. American Psychiatric Association (APA). Diagnostic and Statisti- cal Manual of Mental Disorders, 4th Edition: DSM-IV. United States: APA; 2000.
  3. [39]39. Higgins JPT, Green S. Cochrane Handbook for Systematic Re- views of Interventions 4.2.6. Chishester: Wiley; 2006.

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Authors
Sijbrandij, M., Kunovski, I., & Cuijpers, P.
Affiliations
  • Amsterdam Public Health (NL)
  • Vrije Universiteit Amsterdam (NL)
Corresponding author
Sijbrandij, Marit
Venue
Depression and Anxiety
Published
2016-06-20
Volume
33
Issue
9
Pages
783-791
ISSN
1091-4269 (ISSN-L)
OpenAlex
W2460320365
Cited by
213
References
45
Citations by year
2026: 6 · 2025: 11 · 2024: 14 · 2023: 24 · 2022: 24 · 2021: 28 · 2020: 73 · 2019: 10 · 2018: 13 · 2017: 8 · 2016: 2
FWCI
1.79
Type
journal article
Language
en
Open access
Locations
  • Depression and Anxiety (publishedVersion)
  • PubMed (publishedVersion)
  • Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
  • VU Research Portal (submittedVersion, other-oa)
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Keywords
internet-based cognitive behavioral therapy, post-traumatic stress disorder, PTSD symptom reduction, treatment effectiveness, waitlist control, usual care, access to mental health care
MeSH terms
Adult, Depressive Disorder, Female, Humans, Stress Disorders, Post-Traumatic, Therapy, Computer-Assisted, Comorbidity, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Treatment Outcome, Internet

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