Roles of Growth Hormone and Insulin-like Growth Factor 1 in Mouse Postnatal Growth

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Liu, J.-P., Baker, J., Perkins, A. S., Robertson, E. J., & Efstratiadis, A. (1993) · Cell · doi:10.1016/s0092-8674(05)80084-4 · Cited by 2,855

Role of insulin-like growth factors in embryonic and postnatal growth

Baker, J., Liu, J.-P., Robertson, E. J., & Efstratiadis, A. (1993) · Cell · doi:10.1016/s0092-8674(05)80085-6 · Cited by 2,463

Parental imprinting of the mouse insulin-like growth factor II gene

DeChiara, T. M., Robertson, E. J., & Efstratiadis, A. (1991) · Cell · doi:10.1016/0092-8674(91)90513-x · Cited by 1,783

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

Vu, T. H., Shipley, J. M., Bergers, G., Berger, J. E., Helms, J. A., Hanahan, D., Shapiro, S. D., Senior, R. M., & Werb, Z. (1998) · Cell · doi:10.1016/s0092-8674(00)81169-1 · Cited by 1,750

A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

DeChiara, T. M., Efstratiadis, A., & Robertsen, E. J. (1990) · Nature · doi:10.1038/345078a0 · Cited by 1,642

Normal growth and development in the absence of hepatic insulin-like growth factor I

Yakar, S., Liu, J.-L., Stannard, B., Butler, A., Accili, D., Sauer, B., & LeRoith, D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.13.7324 · Cited by 1,420

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

Teglund, S., McKay, C., Schuetz, E., van Deursen, J. M., Stravopodis, D., Wang, D., Brown, M., Bodner, S., Grosveld, G., & Ihle, J. N. (1998) · Cell · doi:10.1016/s0092-8674(00)81444-0 · Cited by 1,267

A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes

Schaeren-Wiemers, N., & Gerfin-Moser, A. (1993) · Histochemistry · doi:10.1007/bf00267823 · Cited by 1,157

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro.

SALMON, W. D., & Daughaday, W. H. (1957) · PubMed · Cited by 1,084

Nonsense-mediated mRNA decayin health and disease

Frischmeyer, P. A. (1999) · Human Molecular Genetics · doi:10.1093/hmg/8.10.1893 · Cited by 992

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

Udy, G. B., Towers, R. P., Snell, R. G., Wilkins, R. J., Park, S.-H., Ram, P. A., Waxman, D. J., & Davey, H. W. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7239 · Cited by 988

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

Sjögren, K., Liu, J.-L., Blad, K., Skrtic, S., Vidal, O., Wallenius, V., LeRoith, D., Törnell, J., Isaksson, O. G. P., Jansson, J.-O., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.12.7088 · Cited by 938

Growth Hormone and Bone*

Ohlsson, C., Bengtsson, B.-A., Isaksson, O. G. P., Andreassen, T. T., & Slootweg, M. C. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.1.0324 · Cited by 855

Somatomedin-C Mediates Growth Hormone Negative Feedback by Effects on Both the Hypothalamus and the Pituitary

Berelowitz, M., Szabo, M., Frohman, L. A., Firestone, S., Chu, L., & Hintz, R. L. (1981) · Science · doi:10.1126/science.6262917 · Cited by 829

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

Zhou, Y., Xu, B. C., Maheshwari, H. G., He, L., Reed, M., Lozykowski, M., Okada, S., Cataldo, L., Coschigamo, K., Wagner, T. E., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.13215 · Cited by 802

Effects of an Igf1 Gene Null Mutation on Mouse Reproduction

Baker, J., Hardy, M. P., Zhou, J., Bondy, C., Lupu, F., Bellvé, A. R., & Efstratiadis, A. (1996) · Molecular Endocrinology · doi:10.1210/mend.10.7.8813730 · Cited by 674

Assessment of Growth Parameters and Life Span of GHR/BP Gene-Disrupted Mice 1

Coschigano, K. T., Clemmons, D., Bellush, L. L., & Kopchick, J. J. (2000) · Endocrinology · doi:10.1210/endo.141.7.7586 · Cited by 611

Mechanism of the Stimulatory Effect of Growth Hormone on Longitudinal Bone Growth*

ISAKSSON, O. G. P., LINDAHL, A., NILSSON, A., & ISGAARD, J. (1987) · Endocrine Reviews · doi:10.1210/edrv-8-4-426 · Cited by 580

Regulation of insulin-like growth factor I gene expression by growth hormone.

Mathews, L. S., Norstedt, G., & Palmiter, R. D. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.24.9343 · Cited by 553

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

Xu, J., Liao, L., Ning, G., Yoshida-Komiya, H., Deng, C., & O'Malley, B. W. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.120166297 · Cited by 534

Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammation.

De Benedetti, F., Alonzi, T., Moretta, A., Lazzaro, D., Costa, P., Poli, V, Martini, A., Ciliberto, G., & Fattori, E. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119207 · Cited by 529 · cited 1×

Growth Hormone Stimulates Longitudinal Bone Growth Directly

Isaksson, O. G. P., Jansson, J.-O., & Gause, I. A. M. (1982) · Science · doi:10.1126/science.7079756 · Cited by 525

A dual effector theory of growth-hormone action

Green, H., Morikawa, M., & Mxon, T. (1985) · Differentiation · doi:10.1111/j.1432-0436.1985.tb00316.x · Cited by 514

Growth Hormone (GH) Insensitivity Due to Primary GH Receptor Deficiency

ROSENFELD, R. G., ROSENBLOOM, A. L., & GUEVARA-AGUIRRE, J. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-3-369 · Cited by 482

Growth Enhancement of Transgenic Mice Expressing Human Insulin-Like Growth Factor I*

MATHEWS, L. S., HAMMER, R. E., BEHRINGER, R. R., D'ERCOLE, A. J., BELL, G. I., BRINSTER, R. L., & PALMITER, R. D. (1988) · Endocrinology · doi:10.1210/endo-123-6-2827 · Cited by 477

Mechanism of longitudinal bone growth and its regulation by growth plate chondrocytes

Hunziker, E. B. (1994) · Microscopy Research and Technique · doi:10.1002/jemt.1070280606 · Cited by 461

Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation

Gothe, S., Wang, Z., Ng, L., Kindblom, J. M., Barros, A. C., Ohlsson, C., Vennstrom, B., & Forrest, D. (1999) · Genes & Development · doi:10.1101/gad.13.10.1329 · Cited by 445

Radioimmunoassay for insulin-like growth factor-I: solutions to some potential problems and pitfalls

Breier, B. H., Gallaher, B. W., & Gluckman, P. D. (1991) · Journal of Endocrinology · doi:10.1677/joe.0.1280347 · Cited by 415

DNA excision in liver by an albumin-Cre transgene occurs progressively with age

Postic, C., & Magnuson, M. A. (2000) · genesis · doi:10.1002/(sici)1526-968x(200002)26:2<149::aid-gene16>3.0.co;2-v · Cited by 369

Insulin-Like Growth Factors: A Role in Growth Hormone Negative Feedback and Body Weight Regulation via Brain

Tannenbaum, G. S., Guyda, H. J., & Posner, B. I. (1983) · Science · doi:10.1126/science.6338593 · Cited by 360

Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith–Wiedemann and Simpson–Golabi–Behmel syndromes

Eggenschwiler, J., Ludwig, T., Fisher, P., Leighton, P. A., Tilghman, S. M., & Efstratiadis, A. (1997) · Genes & Development · doi:10.1101/gad.11.23.3128 · Cited by 343

Genetics of mouse growth

Efstratiadis, A. (1998) · The International Journal of Developmental Biology · doi:10.1387/ijdb.9853827 · Cited by 343

Chondrocyte Differentiation

Cancedda, R., Cancedda, F. D., & Castagnola, P. (1995) · International Review of Cytology · doi:10.1016/s0074-7696(08)62109-9 · Cited by 332

Regulation by Growth Hormone of Number of Chondrocytes Containing IGF-I in Rat Growth Plate

Nilsson, A., Isgaard, J., Lindahl, A., Dahlström, A., Skottner, A., & Isaksson, O. G. P. (1986) · Science · doi:10.1126/science.3523759 · Cited by 318

Dwarf mice produced by genetic ablation of growth hormone-expressing cells.

Behringer, R. R., Mathews, L. S., Palmiter, R. D., & Brinster, R. L. (1988) · Genes & Development · doi:10.1101/gad.2.4.453 · Cited by 317

The role of STAT proteins in growth hormone signaling

Herrington, J., Smit, L. S., Schwartz, J., & Carter-Su, C. (2000) · Oncogene · doi:10.1038/sj.onc.1203526 · Cited by 275

Endocrine regulation of fetal growth

Fowden, A. (1995) · Reproduction, Fertility and Development · doi:10.1071/rd9950351 · Cited by 272

Insulin-Like Growth Factor I Action on Rat Anterior Pituitary Cells: Suppression of Growth Hormone Secretion and Messenger Ribonucleic Acid Levels*

YAMASHITA, S., & MELMED, S. (1986) · Endocrinology · doi:10.1210/endo-118-1-176 · Cited by 265

Laron Dwarfism and Non-Insulin-Dependent Diabetes Mellitus in the Hnf-1 α Knockout Mouse

Lee, Y.-H., Sauer, B., & Gonzalez, F. J. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.5.3059 · Cited by 262

Igf1 promotes longitudinal bone growth by insulin‐like actions augmenting chondrocyte hypertrophy

Wang, J., Zhou, J., & Bondy, C. A. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.14.1985 · Cited by 253

Identification, Characterization, and Regulation of a Rat Complementary Deoxyribonucleic Acid which Encodes Insulin-Like Growth Factor-I*

MURPHY, L. J., BELL, G. I., LYNN DUCKWORTH, M., & FRIESEN, H. G. (1987) · Endocrinology · doi:10.1210/endo-121-2-684 · Cited by 241

Linear relationship between the volume of hypertrophic chondrocytes and the rate of longitudinal bone growth in growth plates

Breur, G. J., Vanenkevort, B. A., Farnum, C. E., & Wilsman, N. J. (1991) · Journal of Orthopaedic Research · doi:10.1002/jor.1100090306 · Cited by 238

Insulin-Like Growth Factor I Is Essential for Postnatal Growth in Response to Growth Hormone

Liu, J.-L. (1999) · Endocrinology · doi:10.1210/en.140.11.5178 · Cited by 232

Differential effects of insulin-like growth factor I and growth hormone on developmental stages of rat growth plate chondrocytes in vivo.

Hunziker, E. B., Wagner, J., & Zapf, J. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117058 · Cited by 204

Expression of Insulin-Like Growth Factor I Stimulates Normal Somatic Growth in Growth Hormone-Deficient Transgenic Mice

BEHRINGER, R. R., LEWIN, T. M., QUAIFE, C. J., PALMITER, R. D., BRINSTER, R. L., & D’ERCOLE, A. J. (1990) · Endocrinology · doi:10.1210/endo-127-3-1033 · Cited by 195

Growth Hormone Dependence of Somatomedin-C/lnsulin-Like Growth Factor-I and Insulin-Like Growth Factor-ll Messenger Ribonucleic Acids*

Hynes, M. A., Wyk, J. J. V., Brooks, P. J., D’Ercole, A. J., Jansen, M., & Lund, P. K. (1987) · Molecular Endocrinology · doi:10.1210/mend-1-3-233 · Cited by 190

Active role of chondrocyte apoptosis in endochondral ossification

Gibson, G. (1998) · Microscopy Research and Technique · doi:10.1002/(sici)1097-0029(19981015)43:2<191::aid-jemt10>3.0.co;2-t · Cited by 188

Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: in situ localization of its receptor and c-fos messenger ribonucleic acids

Lee, K. (1994) · Endocrinology · doi:10.1210/en.134.1.441 · Cited by 181

Sex differences in the ultradian pattern of plasma growth hormone concentrations in mice

MacLeod, J. N., Pampori, N. A., & Shapiro, B. H. (1991) · Journal of Endocrinology · doi:10.1677/joe.0.1310395 · Cited by 171

Pituitary and Testicular Function in Growth Hormone Receptor Gene Knockout Mice

Chandrashekar, V. (1999) · Endocrinology · doi:10.1210/en.140.3.1082 · Cited by 163

How many homeobox genes does it take to make a pituitary gland?

Watkins-Chow, D. E., & Camper, S. A. (1998) · Trends in Genetics · doi:10.1016/s0168-9525(98)01476-0 · Cited by 158

Etiology of Growth Hormone Deficiency in Little, Ames, and Snell Dwarf Mice*

CHENG, T. C., Beamer, W. G., PHILLIPS, J. A., Bartke, A., Mallonee, R. L., & Dowling, C. E. (1983) · Endocrinology · doi:10.1210/endo-113-5-1669 · Cited by 157

Growth hormone induces multiplication of the slowly cycling germinal cells of the rat tibial growth plate.

Ohlsson, C., Nilsson, A., Isaksson, O. G. P., & Lindahl, A. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.20.9826 · Cited by 152

Prenatal expression of the growth hormone (GH) receptor/binding protein in the rat: a role for GH in embryonic and fetal development?

García-Aragón, J., Lobie, P. E., Muscat, G. E. O., Gobius, K. S., Norstedt, G., & Waters, M. J. (1992) · Development · doi:10.1242/dev.114.4.869 · Cited by 145

Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis

Wang, E., Wang, J., Chin, E. W. M., Zhou, J., & Bondy, C. A. (1995) · Endocrinology · doi:10.1210/endo.136.6.7750499 · Cited by 135

Parathyroid hormone induces sequential c-fos expression in bone cells in vivo: in situ localization of its receptor and c-fos messenger ribonucleic acids.

Lee, K., Deeds, J. D., Chiba, S., UN-NO, M., Bond, A., & Segre, G. V. (1994) · Endocrinology · doi:10.1210/endo.134.1.8275957 · Cited by 135

Differential expression of insulin-like growth factor-I (IGF-I) and IGF- II messenger ribonucleic acid in growing rat bone

SHINAR, D. M., Endo, N., Halperin, D., Rodan, G. A., & Weinreb, M. (1993) · Endocrinology · doi:10.1210/endo.132.3.8440176 · Cited by 134

Growth Allometry of the Organs in Giant Transgenic Mice*

Shea, B. T., Hammer, R. E., & Brinster, R. L. (1987) · Endocrinology · doi:10.1210/endo-121-6-1924 · Cited by 133

Blood oxygen transport and organ weights of small bats and small non-flying mammals

Jürgens, K. D., Bartels, H., & Bartels, R. (1981) · Respiration Physiology · doi:10.1016/0034-5687(81)90009-8 · Cited by 123

Disproportional Skeletal Growth and Markedly Decreased Bone Mineral Content in Growth Hormone Receptor −/− Mice

Sjögren, K., Bohlooly, Y. M., Olsson, B., Coschigano, K. T., Törnell, J., Mohan, S., Isaksson, O. G. P., Baumann, G., Kopchick, J., & Ohlsson, C. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1999.1986 · Cited by 120

Chondrocyte apoptosis in development, aging and disease

Horton, W. E., Feng, L., & Adams, C. S. (1998) · Matrix Biology · doi:10.1016/s0945-053x(98)90024-5 · Cited by 120

Expression of indian hedgehog, bone morphogenetic protein 6 and gli during skeletal morphogenesis1This work was presented in part at the 43rd Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, February 1997.1

Iwasaki, M., Le, A. X., & Helms, J. A. (1997) · Mechanisms of Development · doi:10.1016/s0925-4773(97)00145-7 · Cited by 114

Functional growth hormone (GH) receptors and GH are expressed by preimplantation mouse embryos: A role for GH in early embryogenesis?

Pantaleon, M., Whiteside, E., Harvey, M. B., Barnard, R. T., Waters, M. J., & Kaye, P. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.5125 · Cited by 108

A Personal History of the Origin of the Somatomedin Hypothesis and Recent Challenges to Its Validity

Daughaday, W. H. (1989) · Perspectives in biology and medicine · doi:10.1353/pbm.1989.0006 · Cited by 104

Imprinted gene in postnatal growth role

Itier, J., Tremp, G. L., Léonard, J., Multon, M.-C., Ret, G., Schweighoffer, F., Tocqué, B., Bluet‐Pajot, M., Cormier‐Daire, V., & Dautry, F. (1998) · Nature · doi:10.1038/30120 · Cited by 101

STAT5 Signaling in Sexually Dimorphic Gene Expression and Growth Patterns

Davey, H. W., Wilkins, R. J., & Waxman, D. J. (1999) · The American Journal of Human Genetics · doi:10.1086/302599 · Cited by 95

Growth Hormone and Insulin-Like Growth Factor I Treatment Increase Testicular Luteinizing Hormone Receptors and Steroidogenic Responsiveness of Growth Hormone Deficient Dwarf Mice*

CHATELAIN, P. G., Sánchez, P., & Saez, J. M. (1991) · Endocrinology · doi:10.1210/endo-128-4-1857 · Cited by 94

A model for the development of the hypothalamic–pituitary axis: transcribing the hypophysis

Kioussi, C., Carrière, C., & Rosenfeld, M. G. (1999) · Mechanisms of Development · doi:10.1016/s0925-4773(98)00229-9 · Cited by 93

Cell Population Kinetics of Bone Growth: The First Ten Years of Autoradiographic Studies with Tritiated Thymidine

Kember, N. F. (1971) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-197105000-00029 · Cited by 93

The cell biology of bone growth.

Price, J. S., Oyajobi, B. O., & Russell, R. G. G. (1994) · PubMed · Cited by 91

The time and order of appearance of ossification centers in the albino mouse

Johnson, M. L. (1933) · American Journal of Anatomy · doi:10.1002/aja.1000520203 · Cited by 87

Biosynthetic Somatomedin C (SM-C/IGF-I) Increases the Length and Weight of Snell Dwarf Mice

van Buul-Offers, S. C., Ueda, I., & den Brande, J. L. V. (1986) · Pediatric Research · doi:10.1203/00006450-198609000-00002 · Cited by 85

Multiphasic growth curve analysis.

Koops, W. J. (1986) · PubMed · Cited by 82

EMK Protein Kinase-Null Mice: Dwarfism and Hypofertility Associated with Alterations in the Somatotrope and Prolactin Pathways

Bessone, S., Vidal, F., Bouc, Y. L., Epelbaum, J., Bluet‐Pajot, M., & Darmon, M. Y. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9379 · Cited by 81

Natural history of the classical form of primary growth hormone (GH) resistance (Laron syndrome).

Laron, Z. (1999) · PubMed · Cited by 78

Regional variation of insulin-like growth factor-I gene expression in mature rat bone and cartilage

Lazowski, D.-A., Fraher, L. J., Hodsman, A. B., Steer, B. M., Modrowski, D., & Han, V. K. M. (1994) · Bone · doi:10.1016/8756-3282(94)90282-8 · Cited by 76

Kinetic Studies on Epiphyseal Growth Cartilage in the Normal Mouse

Vanky, P., Brockstedt, U., Hjerpe, A., & Wikström, B. (1998) · Bone · doi:10.1016/s8756-3282(97)00286-x · Cited by 71

CELL KINETICS OF GROWTH CARTILAGE IN THE RAT TIBIA II. MEASUREMENTS DURING AGEING

Walker, K. V. R., & Kember, N. F. (1972) · Cell Proliferation · doi:10.1111/j.1365-2184.1972.tb00379.x · Cited by 71

Thyroid hormone actions on cartilage and bone: interactions with other hormones at the epiphyseal plate and effects on linear growth

Williams, G. R., Robson, H., & Shalet, S. M. (1998) · Journal of Endocrinology · doi:10.1677/joe.0.1570391 · Cited by 69

The Insulin-Sensitive Glucose Transporter (GLUT4) Is Involved in Early Bone Growth in Control and Diabetic Mice, But Is Regulated through the Insulin-Like Growth Factor I Receptor

Maor, G., & Karnieli, E. (1999) · Endocrinology · doi:10.1210/en.140.4.1841 · Cited by 65

Visual Demonstration of Growth Hormone Receptors on Human Growth Plate Chondrocytes*

Werther, G. A., HAYNES, K. M., Barnard, R. T., et al. (1990) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-70-6-1725 · Cited by 65

Is the Laron Mouse an Accurate Model of Laron Syndrome?

Kopchick, J. J., & Laron, Z. (1999) · Molecular Genetics and Metabolism · doi:10.1006/mgme.1999.2890 · Cited by 60

CELL KINETICS OF GROWTH CARTILAGE IN THE RAT TIBIA I. MEASUREMENTS IN YOUNG MALE RATS

Walker, K. V. R., & Kember, N. F. (1972) · Cell Proliferation · doi:10.1111/j.1365-2184.1972.tb00378.x · Cited by 59

Growth hormone receptor abundance in tibial growth plates of uremic rats: GH/IGF-I treatment

Edmondson, S. R., Baker, N. L., Oh, J. S., et al. (2000) · Kidney International · doi:10.1046/j.1523-1755.2000.00141.x · Cited by 50

Differential regulation of tissue insulin-like growth factor-binding protein (IGFBP)-3, IGF-I and IGF type 1 receptor mRNA levels, and serum IGF-I and IGFBP concentrations by growth hormone and IGF-I

LEMMEY, A. B., Glassford, J., Flick-Smith, H. C., Holly, J. M. P., & Pell, J. M. (1997) · Journal of Endocrinology · doi:10.1677/joe.0.1540319 · Cited by 49

Sex and species differences in mouse and rat forebrain commissures depend on the method of adjusting for brain size

Bishop, K. M., & Wahlsten, D. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01088-9 · Cited by 46

Growth hormone induces insulin‐like growth factor‐I gene transcription by a synergistic action of STAT5 and HNF‐1α

Metón, I., Boot, E. P. J., Sussenbach, J. S., et al. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00064-2 · Cited by 45

Human Insulin-Like Growth Factor (IGF) Binding Protein-1 Inhibits IGF-I-Stimulated Body Growth but Stimulates Growth of the Kidney in Snell Dwarf Mice

van Buul-Offers, S. C., Kleffens, M. D.-V., Koster, J. G., Lindenbergh-Kortleve, D. J., Gresnigt, M. G., Drop, S. L. S., Hoogerbrugge, C. M., Bloemen, R. J., KOEDAM, J. A., & van Neck, J. W. (2000) · Endocrinology · doi:10.1210/endo.141.4.7418 · Cited by 43

Mouse growth hormone-binding protein and growth hormone receptor transcripts are produced from a single gene by alternative splicing.

Edens, A., Southard, J. N., & Talamantes, F. J. (1994) · Endocrinology · doi:10.1210/endo.135.6.7988474 · Cited by 43

Cell kinetics and the control of bone growth

Kember, N. F. (1993) · Acta Paediatrica · doi:10.1111/j.1651-2227.1993.tb12932.x · Cited by 36

Regulation of testicular insulin-like growth factor-I in pubertal growth hormone-deficient male rats

Spiteri-Grech, J., Bartlett, J. M. S., & Nieschlag, E. (1991) · Journal of Endocrinology · doi:10.1677/joe.0.1310279 · Cited by 30

Stimulation of sulfate and thymidine incorporation into hypophysectomized rat cartilage by growth hormone and insulin-like growth factor-I in vitro: The somatomedin hypothesis revisited

Salmon, W. D., & BURKHALTER, V. J. (1997) · Journal of Laboratory and Clinical Medicine · doi:10.1016/s0022-2143(97)90076-7 · Cited by 25

Subcellular distribution of the long and short isoforms of the growth hormone (GH) receptor in rat adipocytes: both isoforms participate in specific binding of GH

Frick, G. P., Tai, L. R., & GOODMAN, H. M. (1994) · Endocrinology · doi:10.1210/en.134.1.307 · Cited by 22

Altered Postnatal Expression of Insulin-Like Growth Factor-I (IGF-I) and Type X Collagen Preceding the Perthes' Disease–Like Lesion of a Rat Model

Kikkawa, M., Imai, S., & Hukuda, S. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.1.111 · Cited by 20

Insulin-like Growth Factor-I (IGF-I) and IGF-I Receptor (IGF-IR) Immunoreactivity in Normal and Osteopetrotic (toothless,tl/tl) Rat Tibia

Joseph, B. K., Marks, S. C., Hume, D. A., Waters, M. J., & Symons, A. L. (1999) · Growth Factors · doi:10.3109/08977199909069146 · Cited by 16

The CCAAT/enhancer-binding protein-alpha is expressed in the germinal layer of the growth plate: colocalisation with the growth hormone receptor

Vidal, N. O. A., Ekberg, S., Enerbäck, S., Lindahl, A. H., & Ohlsson, C. (1997) · Journal of Endocrinology · doi:10.1677/joe.0.1550433 · Cited by 11

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