Neuroanatomy of the kisspeptin signaling system in mammals: comparative and developmental aspects

Central and Peripheral Circadian Clocks in Mammals

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A role for kisspeptins in the regulation of gonadotropin secretion in the mouse

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Regulation of Kiss1 gene expression in the brain of the female mouse

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Activation of Gonadotropin-Releasing Hormone Neurons by Kisspeptin as a Neuroendocrine Switch for the Onset of Puberty

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TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for neurokinin B in the central control of reproduction

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Kisspeptin Activation of Gonadotropin Releasing Hormone Neurons and Regulation of KiSS-1 mRNA in the Male Rat

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AXOR12, a Novel Human G Protein-coupled Receptor, Activated by the Peptide KiSS-1

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Increased hypothalamic GPR54 signaling: A potential mechanism for initiation of puberty in primates

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Postnatal Development of Kisspeptin Neurons in Mouse Hypothalamus; Sexual Dimorphism and Projections to Gonadotropin-Releasing Hormone Neurons

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Kisspeptin Signaling in the Brain

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Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse

Navarro, V. M., Gottsch, M. L., Chavkin, C., Okamura, H., Clifton, D. K., & Steiner, R. A. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1569-09.2009 · Cited by 779 · see citing works

Minireview: Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cells of the Arcuate Nucleus: A Central Node in the Control of Gonadotropin-Releasing Hormone Secretion

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Differential Regulation of KiSS-1 mRNA Expression by Sex Steroids in the Brain of the Male Mouse

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Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B

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Definition of Estrogen Receptor Pathway Critical for Estrogen Positive Feedback to Gonadotropin-Releasing Hormone Neurons and Fertility

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Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat

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Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene

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Kiss1 Neurons in the Forebrain as Central Processors for Generating the Preovulatory Luteinizing Hormone Surge

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Involvement of anteroventral periventricular metastin/kisspeptin neurons in estrogen positive feedback action on luteinizing hormone release in female rats

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Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat

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Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha

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Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats

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Discovery of a receptor related to the galanin receptors

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Sexual Differentiation of Kiss1 Gene Expression in the Brain of the Rat

Kauffman, A. S., Gottsch, M. L., Roa, J., Byquist, A. C., Crown, A., Clifton, D. K., Hoffman, G. E., Steiner, R. A., & Tena‐Sempere, M. (2007) · Endocrinology · doi:10.1210/en.2006-1540 · Cited by 493 · see citing works

Central and Peripheral Administration of Kisspeptin‐10 Stimulates the Hypothalamic‐Pituitary‐Gonadal Axis

Thompson, E. L., Patterson, M., Murphy, K. G., Smith, K. L., Dhillo, W. S., Todd, J. F., Ghatei, M. A., & Bloom, S. R. (2004) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2004.01240.x · Cited by 482 · see citing works

Advanced vaginal opening and precocious activation of the reproductive axis by KiSS‐1 peptide, the endogenous ligand of GPR54

Navarro, V. M., Fernández‐Fernández, R., Castellano, J. M., Roa, J., Mayen, A., Barreiro, M. L., Gaytán, F., Aguilar, E., Pinilla, L., Diéguez, C., et al. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.072298 · Cited by 466 · see citing works

Characterization of the potent luteinizing hormone-releasing activity of KiSS-1 peptide, the natural ligand of GPR54

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Kisspeptin–GPR54 Signaling Is Essential for Preovulatory Gonadotropin-Releasing Hormone Neuron Activation and the Luteinizing Hormone Surge

Clarkson, J., d'Anglemont de Tassigny, X., Moreno, A. S., Colledge, W. H., & Herbison, A. E. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1775-08.2008 · Cited by 436 · see citing works

KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season

Smith, J. T., Clay, C. M., Caraty, A., & Clarke, I. J. (2007) · Endocrinology · doi:10.1210/en.2006-1435 · Cited by 404 · see citing works

Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys

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Variation in Kisspeptin and RFamide-Related Peptide (RFRP) Expression and Terminal Connections to Gonadotropin-Releasing Hormone Neurons in the Brain: A Novel Medium for Seasonal Breeding in the Sheep

Smith, J. T., Coolen, L. M., Kriegsfeld, L. J., Sari, I. P., Jaafarzadehshirazi, M. R., Maltby, M., Bateman, K., Goodman, R. L., Tilbrook, A. J., Ubuka, T., et al. (2008) · Endocrinology · doi:10.1210/en.2008-0581 · Cited by 387 · see citing works

Minireview: Kisspeptin Neurons as Central Processors in the Regulation of Gonadotropin-Releasing Hormone Secretion

Lemko, H. M. D., Clifton, D. K., & Steiner, R. A. (2005) · Endocrinology · doi:10.1210/en.2005-1282 · Cited by 371 · see citing works

Characterization of Kiss1 neurons using transgenic mouse models

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Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: The case for the rostral periventricular area of the third ventricle (RP3V)

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Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain

Clarkson, J., D’Anglemont de Tassigny, X., Colledge, W. H., Caraty, A., & Herbison, A. E. (2009) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2009.01892.x · Cited by 346 · see citing works

Timing and completion of puberty in female mice depend on estrogen receptor α-signaling in kisspeptin neurons

Mayer, C., Acosta‐Martínez, M., Dubois, S. L., Wolfe, A., Radovick, S., Boehm, U., & Levine, J. E. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012406108 · Cited by 344 · see citing works

Kisspeptin Acts Directly and Indirectly to Increase Gonadotropin-Releasing Hormone Neuron Activity and Its Effects Are Modulated by Estradiol

Pielecka-Fortuna, J., Chu, Z., & Moenter, S. M. (2007) · Endocrinology · doi:10.1210/en.2007-1365 · Cited by 341 · see citing works

Distribution and Postnatal Development of Gpr54 Gene Expression in Mouse Brain and Gonadotropin-Releasing Hormone Neurons

Herbison, A. E., de Tassigny, X. D., Doran, J., & Colledge, W. H. (2009) · Endocrinology · doi:10.1210/en.2009-0552 · Cited by 316 · see citing works

The kisspeptin system of the human hypothalamus: sexual dimorphism and relationship with gonadotropin‐releasing hormone and neurokinin B neurons

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Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits

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The Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cell Population of the Arcuate Nucleus: Sex Differences and Effects of Prenatal Testosterone in Sheep

Cheng, G., Coolen, L. M., Padmanabhan, V., Goodman, R. L., & Lehman, M. N. (2009) · Endocrinology · doi:10.1210/en.2009-0541 · Cited by 304 · see citing works

Repetitive Activation of Hypothalamic G Protein-Coupled Receptor 54 with Intravenous Pulses of Kisspeptin in the Juvenile Monkey (Macaca mulatta) Elicits a Sustained Train of Gonadotropin-Releasing Hormone Discharges

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Kisspeptin Cells in the Ewe Brain Respond to Leptin and Communicate with Neuropeptide Y and Proopiomelanocortin Cells

Backholer, K., Smith, J. T., Rao, A. V. N., Pereira, A., Iqbal, J., Ogawa, S., Li, Q., & Clarke, I. J. (2010) · Endocrinology · doi:10.1210/en.2009-1190 · Cited by 289 · see citing works

Kisspeptin Can Stimulate Gonadotropin-Releasing Hormone (GnRH) Release by a Direct Action at GnRH Nerve Terminals

de Tassigny, X. D., Fagg, L. A., Carlton, M. B. L., & Colledge, W. H. (2008) · Endocrinology · doi:10.1210/en.2007-1487 · Cited by 287 · see citing works

Kisspeptin Mediates the Photoperiodic Control of Reproduction in Hamsters

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Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus: morphologic evidence of interrelated function within the arcuate nucleus

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Structural Interactions between Kisspeptin and GnRH Neurons in the Mediobasal Hypothalamus of the Male Rhesus Monkey (Macaca mulatta) as Revealed by Double Immunofluorescence and Confocal Microscopy

Ramaswamy, S., Guerriero, K. A., Gibbs, R. B., & Plant, T. M. (2008) · Endocrinology · doi:10.1210/en.2008-0438 · Cited by 279 · see citing works

An increase in kisspeptin-54 release occurs with the pubertal increase in luteinizing hormone-releasing hormone-1 release in the stalk-median eminence of female rhesus monkeys in vivo

Keen, K. L., Wegner, F. H., Bloom, S. R., Ghatei, M. A., & Terasawa, E. (2008) · Endocrinology · doi:10.1210/en.2008-0231 · Cited by 273 · see citing works

Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus

Ramaswamy, S., Seminara, S. B., Ali, B., Ciofi, P., Amin, N. A., & Plant, T. M. (2010) · Endocrinology · doi:10.1210/en.2010-0223 · Cited by 267 · see citing works

Regulation of Hypothalamic Expression of KiSS-1 and GPR54 Genes by Metabolic Factors: Analyses Using Mouse Models and a Cell Line

Luque, R. M., Kineman, R. D., & Tena‐Sempere, M. (2007) · Endocrinology · doi:10.1210/en.2007-0500 · Cited by 261 · see citing works

Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse

Navarro, V. M., Gottsch, M. L., Wu, M., García-Galiano, D., Hobbs, S. J., Bosch, M. A., Pinilla, L., Clifton, D. K., Dearth, A., Ronnekleiv, O. K., et al. (2011) · Endocrinology · doi:10.1210/en.2011-1143 · Cited by 254 · see citing works

Kisspeptin Is Essential for the Full Preovulatory LH Surge and Stimulates GnRH Release from the Isolated Ovine Median Eminence

Smith, J. T., Li, Q., Yap, K. S., Shahab, M., Roseweir, A. K., Millar, R. P., & Clarke, I. J. (2011) · Endocrinology · doi:10.1210/en.2010-1225 · Cited by 254 · see citing works

Evidence That Dynorphin Plays a Major Role in Mediating Progesterone Negative Feedback on Gonadotropin-Releasing Hormone Neurons in Sheep

Goodman, R. L., Coolen, L. M., Anderson, G. M., Hardy, S. L., Valent, M., Connors, J. M., Fitzgerald, M. E., & Lehman, M. N. (2004) · Endocrinology · doi:10.1210/en.2003-1305 · Cited by 251 · see citing works

Kisspeptin Directly Excites Anorexigenic Proopiomelanocortin Neurons but Inhibits Orexigenic Neuropeptide Y Cells by an Indirect Synaptic Mechanism

Fu, L.-Y., & van den Pol, A. N. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.2098-10.2010 · Cited by 243 · see citing works

Postnatal Development of an Estradiol-Kisspeptin Positive Feedback Mechanism Implicated in Puberty Onset

Clarkson, J., Boon, W. C., Simpson, E. R., & Herbison, A. E. (2009) · Endocrinology · doi:10.1210/en.2008-1733 · Cited by 232 · see citing works

Environmental Control of Kisspeptin: Implications for Seasonal Reproduction

Greives, T. J., Mason, A. O., Scotti, M. L., Levine, J., Ketterson, E. D., Kriegsfeld, L. J., & Demas, G. E. (2006) · Endocrinology · doi:10.1210/en.2006-1249 · Cited by 209 · see citing works

Kisspeptin Neurons in the Ovine Arcuate Nucleus and Preoptic Area Are Involved in the Preovulatory Luteinizing Hormone Surge

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Neurokinin B and the hypothalamic regulation of reproduction

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Elevated KiSS‐1 Expression in the Arcuate Nucleus Prior to the Cyclic Preovulatory Gonadotrophin‐Releasing Hormone/Lutenising Hormone Surge in the Ewe Suggests a Stimulatory Role for Kisspeptin in Oestrogen‐Positive Feedback

Estrada, K. M., Clay, C. M., Pompolo, S., Smith, J. T., & Clarke, I. J. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01485.x · Cited by 203 · see citing works

Direct Pituitary Effects of Kisspeptin: Activation of Gonadotrophs and Somatotrophs and Stimulation of Luteinising Hormone and Growth Hormone Secretion

Gutiérrez‐Pascual, E., Martínez‐Fuentes, A. J., Pinilla, L., Tena‐Sempere, M., Malagón, M. M., & Castano, J. P. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2007.01558.x · Cited by 200 · see citing works

Neural activation following sexual behavior in the male and female rat brain

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Down‐Regulation of Hypothalamic <i>Kisspeptin</i> and its Receptor, <i>Kiss1r</i> , mRNA Expression is Associated with Stress‐Induced Suppression of Luteinising Hormone Secretion in the Female Rat

Kinsey‐Jones, J. S., Li, X. F., Knox, A. M. I., Wilkinson, E. S., Zhu, X. L., Chaudhary, A. A., Milligan, S. R., Lightman, S. L., & O’Byrne, K. T. (2009) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01807.x · Cited by 196 · see citing works

Circadian Regulation of Kiss1 Neurons: Implications for Timing the Preovulatory Gonadotropin-Releasing Hormone/Luteinizing Hormone Surge

Robertson, J. L., Clifton, D. K., de la Iglesia, H. O., Steiner, R. A., & Kauffman, A. S. (2009) · Endocrinology · doi:10.1210/en.2009-0247 · Cited by 189 · see citing works

Kisspeptin Is Present in Ovine Hypophysial Portal Blood But Does Not Increase during the Preovulatory Luteinizing Hormone Surge: Evidence that Gonadotropes Are Not Direct Targets of Kisspeptin in Vivo

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Molecular Mapping of the Neural Pathways Linking Leptin to the Neuroendocrine Reproductive Axis

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Forebrain projections of arcuate neurokinin B neurons demonstrated by anterograde tract-tracing and monosodium glutamate lesions in the rat

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Projections of Arcuate Nucleus and Rostral Periventricular Kisspeptin Neurons in the Adult Female Mouse Brain

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Anatomy of the kisspeptin neural network in mammals

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Comparative insights of the kisspeptin/kisspeptin receptor system: Lessons from non-mammalian vertebrates

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Regulation of Kiss1 Expression by Sex Steroids in the Amygdala of the Rat and Mouse

Kim, J., Semaan, S. J., Clifton, D. K., Steiner, R. A., Dhamija, S., & Kauffman, A. S. (2011) · Endocrinology · doi:10.1210/en.2010-1498 · Cited by 162 · see citing works

Characterisation of Arcuate Nucleus Kisspeptin/Neurokinin B Neuronal Projections and Regulation during Lactation in the Rat

True, C. A., Kirigiti, M. A., Ciofi, P., Grove, K. L., & Smith, M. S. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.02076.x · Cited by 159 · see citing works

Significance of Neonatal Testicular Sex Steroids to Defeminize Anteroventral Periventricular Kisspeptin Neurons and the GnRH/LH Surge System in Male Rats1

Homma, T., SAKAKIBARA, M., Yamada, S., Kinoshita, M., Iwata, K., Tomikawa, J., Kanazawa, T., Matsui, H., Takatsu, Y., Ohtaki, T., et al. (2009) · Biology of Reproduction · doi:10.1095/biolreprod.109.078311 · Cited by 153 · see citing works

Inhibition of Metastin (Kisspeptin-54)-GPR54 Signaling in the Arcuate Nucleus-Median Eminence Region during Lactation in Rats

Yamada, S., Uenoyama, Y., Kinoshita, M., Iwata, K., Takase, K., Matsui, H., Adachi, S., Inoue, K., Maeda, K., & Tsukamura, H. (2007) · Endocrinology · doi:10.1210/en.2006-1529 · Cited by 152 · see citing works

Colocalization of Progesterone Receptors in Parvicellular Dynorphin Neurons of the Ovine Preoptic Area and Hypothalamus

Foradori, C. D., Coolen, L. M., Fitzgerald, M. E., Skinner, D. C., Goodman, R. L., & Lehman, M. N. (2002) · Endocrinology · doi:10.1210/en.2002-220586 · Cited by 149 · see citing works

KiSS‐1 expression and metastin‐like immunoreactivity in the rat brain

Brailoiu, G. C., Dun, S. L., Ohsawa, M., Yin, D., Yang, J., Chang, J. K., Brailoiu, E., & Dun, N. J. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20350 · Cited by 146 · see citing works

KiSS‐1 and GPR54 Genes are Co‐Expressed in Rat Gonadotrophs and Differentially Regulated In Vivo by Oestradiol and Gonadotrophin‐Releasing Hormone

Richard, N., Galmiche, G., Corvaisier, S., Caraty, A., & Kottler, M. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01653.x · Cited by 142 · see citing works

Exposure to a Complex Cocktail of Environmental Endocrine-Disrupting Compounds Disturbs the Kisspeptin/GPR54 System in Ovine Hypothalamus and Pituitary Gland

Bellingham, M., Fowler, P., Amezaga, M. R., Rhind, S. M., Cotinot, C., Mandon‐Pepin, B., Sharpe, R. M., & Evans, N. P. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.0900699 · Cited by 142 · see citing works

The neuroanatomy of the kisspeptin system in the mammalian brain

Mikkelsen, J. D., & Simonneaux, V. (2008) · Peptides · doi:10.1016/j.peptides.2008.09.004 · Cited by 139 · see citing works

Development, Sex Steroid Regulation, and Phenotypic Characterization of RFamide-Related Peptide (Rfrp) Gene Expression and RFamide Receptors in the Mouse Hypothalamus

Poling, M. C., Kim, J., Dhamija, S., & Kauffman, A. S. (2012) · Endocrinology · doi:10.1210/en.2011-2049 · Cited by 134 · see citing works

KiSS-1 and Reproduction: Focus on Its Role in the Metabolic Regulation of Fertility

Tena-Sempere, M. (2006) · Neuroendocrinology · doi:10.1159/000095549 · Cited by 132 · see citing works

Sex differences in the regulation of Kiss1/NKB neurons in juvenile mice: implications for the timing of puberty

Kauffman, A. S., Navarro, V. M., Kim, J. P., Clifton, D. K., & Steiner, R. A. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00461.2009 · Cited by 132 · see citing works

Kisspeptin signalling in the brain: Steroid regulation in the rodent and ewe

Smith, J. T. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.04.002 · Cited by 132 · see citing works

Sexually dimorphic expression of hypothalamic estrogen receptors α and β and kiss1 in neonatal male and female rats

Cao, J., & Patisaul, H. B. (2011) · The Journal of Comparative Neurology · doi:10.1002/cne.22648 · Cited by 127 · see citing works

Colocalisation of Dynorphin A and Neurokinin B Immunoreactivity in the Arcuate Nucleus and Median Eminence of the Sheep

Foradori, C. D., Amstalden, M., Goodman, R. L., & Lehman, M. N. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01445.x · Cited by 126 · see citing works

Kisspeptin-GPR54 Signaling in Mouse NO-Synthesizing Neurons Participates in the Hypothalamic Control of Ovulation

Hanchate, N. K., Parkash, J., Bellefontaine, N., Mazur, D., Colledge, W. H., de Tassigny, X. D., & Prévot, V. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.4765-11.2012 · Cited by 125 · see citing works

Direct kisspeptin-10 stimulation on luteinizing hormone secretion from bovine and porcine anterior pituitary cells

Suzuki, S., Kadokawa, H., & HASHIZUME, T. (2007) · Animal Reproduction Science · doi:10.1016/j.anireprosci.2007.05.016 · Cited by 124 · see citing works

Possible Role of Oestrogen in Pubertal Increase of Kiss1/Kisspeptin Expression in Discrete Hypothalamic Areas of Female Rats

Takase, K., Uenoyama, Y., Inoue, N., Matsui, H., Yamada, S., Shimizu, M., Homma, T., Tomikawa, J., Kanda, S., Matsumoto, H., et al. (2009) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2009.01868.x · Cited by 123 · see citing works

Excitatory Effects of the Puberty-Initiating Peptide Kisspeptin and Group I Metabotropic Glutamate Receptor Agonists Differentiate Two Distinct Subpopulations of Gonadotropin-Releasing Hormone Neurons

Dumalska, I., Wu, M., Morozova, E., Liu, R., van den Pol, A. N., & Alreja, M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1225-08.2008 · Cited by 121 · see citing works

Evidence of a Role for Kisspeptin and Neurokinin B in Puberty of Female Sheep

Nestor, C. C., Briscoe, A. M. S., Davis, S. M., Valent, M., Goodman, R. L., & Hileman, S. M. (2012) · Endocrinology · doi:10.1210/en.2011-2009 · Cited by 118 · see citing works

Functional and evolutionary insights into vertebrate kisspeptin systems from studies of fish brain

Akazome, Y., Kanda, S., Okubo, K., & Oka, Y. (2010) · Journal of Fish Biology · doi:10.1111/j.1095-8649.2009.02496.x · Cited by 115 · see citing works

Neurobiological mechanisms underlying kisspeptin activation of gonadotropin-releasing hormone (GnRH) neurons at puberty

Clarkson, J., Han, S., Liu, X., Lee, K., & Herbison, A. E. (2010) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2010.01.026 · Cited by 115 · see citing works

Regulation of Circulating Gonadotropins by the Negative Effects of Ovarian Hormones in Mares1

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Mapping of Kisspeptin Fibres in the Brain of the Pro‐Oestrous Rat

Desroziers, E., Mikkelsen, J. D., Simonneaux, V., Keller, M., Tillet, Y., Caraty, A., & Franceschini, I. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.02053.x · Cited by 111 · see citing works

Facilitatory and inhibitory effects of electrochemical stimulation of the amygdala on the release of luteinizing hormone

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Ultrastructural Evidence of Kisspeptin-Gonadotrophin-Releasing Hormone (GnRH) Interaction in the Median Eminence of Female Rats: Implication of Axo-Axonal Regulation of GnRH Release

Uenoyama, Y., Inoue, N., Pheng, V., Homma, T., Takase, K., Yamada, S., Ajiki, K., Ichikawa, M., Okamura, H., Maeda, K., et al. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02199.x · Cited by 106 · see citing works

Dual Phenotype Kisspeptin-Dopamine Neurones of the Rostral Periventricular Area of the Third Ventricle Project to Gonadotrophin-Releasing Hormone Neurones

Clarkson, J., & Herbison, A. E. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02107.x · Cited by 104 · see citing works

BAX-Dependent and BAX-Independent Regulation of Kiss1 Neuron Development in Mice

Semaan, S. J., Murray, E. K., Poling, M. C., Dhamija, S., Forger, N. G., & Kauffman, A. S. (2010) · Endocrinology · doi:10.1210/en.2010-0783 · Cited by 103 · see citing works

Kisspeptin neurons from mice to men: similarities and differences

Goodman, R. L., & Lehman, M. N. (2012) · Endocrinology · doi:10.1210/en.2012-1550 · Cited by 103 · see citing works

Kisspeptin immunoreactive neurons in the equine hypothalamus

Decourt, C., Tillet, Y., Caraty, A., Franceschini, I., & Briant, C. (2008) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2008.07.008 · Cited by 102 · see citing works

Differential Regulation of Kiss1 Expression by Melatonin and Gonadal Hormones in Male and Female Syrian Hamsters

Ansel-Bollepalli, L., Bolborea, M., Bentsen, A. H., Klosen, P., Mikkelsen, J. D., & Simonneaux, V. (2010) · Journal of Biological Rhythms · doi:10.1177/0748730410361918 · Cited by 101 · see citing works

Evidence That Down Regulation of Hypothalamic KiSS‐1 Expression is Involved in the Negative Feedback Action of Testosterone to Regulate Luteinising Hormone Secretion in the Adult Male Rhesus Monkey (Macaca mulatta)

Shibata, M., Friedman, R. L., Ramaswamy, S., & Plant, T. M. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2007.01549.x · Cited by 98 · see citing works

Suppression of kisspeptin expression and gonadotropic axis sensitivity following exposure to inhibitory day lengths in female Siberian hamsters

MASON, A., GREIVES, T., Scotti, M. L., LEVINE, J., FROMMEYER, S., Ketterson, E. D., Demas, G. E., & Kriegsfeld, L. J. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.07.004 · Cited by 98 · see citing works

Co‐Localisation of Kisspeptin with Galanin or Neurokinin B in Afferents to Mouse GnRH Neurones

Kalló, I., Vida, B., Deli, L., Molnár, C. S., Hrabovszky, E., Caraty, A., Ciofi, P., Coen, C. W., & Liposits, Z. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02262.x · Cited by 94 · see citing works

Developmental Changes in the Expression of Kisspeptin mRNA in Rat Hypothalamus

Takumi, K., Iijima, N., & Ozawa, H. (2010) · Journal of Molecular Neuroscience · doi:10.1007/s12031-010-9430-1 · Cited by 92 · see citing works

Effects of aromatase mutation (ArKO) on the sexual differentiation of kisspeptin neuronal numbers and their activation by same versus opposite sex urinary pheromones

Bakker, J., Pierman, S., & González-Martı́nez, D. (2009) · Hormones and Behavior · doi:10.1016/j.yhbeh.2009.11.005 · Cited by 91 · see citing works

Neonatal Lipopolysaccharide Exposure Delays Puberty and Alters Hypothalamic Kiss1 and Kiss1r mRNA Expression in the Female Rat

Knox, A. M. I., Li, X. F., Kinsey‐Jones, J. S., Wilkinson, E. S., Wu, X., Cheng, Y., Milligan, S. R., Lightman, S. L., & O’Byrne, K. T. (2009) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2009.01885.x · Cited by 88 · see citing works

Developmental and Steroidogenic Effects on the Gene Expression of RFamide Related Peptides and their Receptor in the Rat Brain and Pituitary Gland

Quennell, J. H., Rizwan, M. Z., Relf, H.-L., & Anderson, G. M. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01963.x · Cited by 83 · see citing works

Reproductive Hormone-Dependent and -Independent Contributions to Developmental Changes in Kisspeptin in GnRH-Deficient Hypogonadal Mice

Gill, J. C., Wang, O., Kakar, S., Martinelli, E., Carroll, R. S., & Kaiser, U. B. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011911 · Cited by 79 · see citing works

Kisspeptin neurons co‐express met‐enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus

Porteous, R. W., Petersen, S. L., Yeo, S., Bhattarai, J. P., Ciofi, P., de Tassigny, X. D., Colledge, W. H., Caraty, A., & Herbison, A. E. (2011) · The Journal of Comparative Neurology · doi:10.1002/cne.22716 · Cited by 74 · see citing works

Expression of a Functional G Protein-Coupled Receptor 54-Kisspeptin Autoregulatory System in Hypothalamic Gonadotropin-Releasing Hormone Neurons

Quaynor, S. D., Hu, L., Leung, P. K., Feng, H., Mores, N., Krsmanović, L. Z., & Catt, K. J. (2007) · Molecular Endocrinology · doi:10.1210/me.2007-0207 · Cited by 74 · see citing works

Biological and Anatomical Evidence for Kisspeptin Regulation of the Hypothalamic-Pituitary-Gonadal Axis of Estrous Horse Mares

Magee, C., Foradori, C. D., Bruemmer, J. E., Arreguin-Arevalo, J. A., McCue, P. M., Handa, R. J., Squires, E. L., & Clay, C. M. (2009) · Endocrinology · doi:10.1210/en.2008-1698 · Cited by 72 · see citing works

Morphological Evidence for Direct Interaction between Kisspeptin and Gonadotropin-Releasing Hormone Neurons at the Median Eminence of the Male Goat: An Immunoelectron Microscopic Study

Matsuyama, S., Ohkura, S., Mogi, K., Wakabayashi, Y., Mori, Y., Tsukamura, H., Maeda, K., Ichikawa, M., & Okamura, H. (2011) · Neuroendocrinology · doi:10.1159/000331576 · Cited by 70 · see citing works

Postmenopausal increase in KiSS-1, GPR54, and luteinizing hormone releasing hormone (LHRH-1) mRNA in the basal hypothalamus of female rhesus monkeys

Kim, W., Jessen, H. M., Auger, A. P., & Terasawa, E. (2008) · Peptides · doi:10.1016/j.peptides.2008.06.005 · Cited by 70 · see citing works

Electrical and Morphological Characteristics of Anteroventral Periventricular Nucleus Kisspeptin and Other Neurons in the Female Mouse

Ducret, E., Gaidamaka, G., & Herbison, A. E. (2010) · Endocrinology · doi:10.1210/en.2009-1480 · Cited by 70 · see citing works

Control of Gonadotropin Secretion in the Male during Puberty: A Decrease in Response to Steroid Inhibitory Feedback in the Absence of an Increase in Steroid-Independent Drive in the Sheep*

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Kisspeptin Cells in the Ovine Arcuate Nucleus Express Prolactin Receptor but not Melatonin Receptor

Li, Q., Rao, A., Pereira, A. Z., Clarke, I. J., & Smith, J. T. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02195.x · Cited by 69 · see citing works

Absence of Gonadotropin-Releasing Hormone 1 and Kiss1 Activation in α-Fetoprotein Knockout Mice: Prenatal Estrogens Defeminize the Potential to Show Preovulatory Luteinizing Hormone Surges

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Developmental Changes in Hypothalamic Kiss1 Expression during Activation of the Pulsatile Release of Luteinising Hormone in Maturing Ewe Lambs

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Maturation of kisspeptinergic neurons coincides with puberty onset in male rats

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Ultrastructure and synaptic organization of luteinizing hormone‐releasing hormone (LHRH) neurons in the anestrous ewe

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Tonic Control of Kisspeptin Release in Prepubertal Monkeys: Implications to the Mechanism of Puberty Onset

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Studies of the Localisation of Kisspeptin Within the Pituitary of the Rhesus Monkey (Macaca mulatta) and the Effect of Kisspeptin on the Release of Non‐Gonadotropic Pituitary Hormones

Ramaswamy, S., Gibbs, R. B., & Plant, T. M. (2009) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2009.01905.x · Cited by 53 · see citing works

Immunocytochemical localization of kisspeptin neurons in the rat forebrain with special reference to sexual dimorphism and interaction with GnRH neurons

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Gonadotrophin‐Inhibitory Hormone: A Multifunctional Neuropeptide

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Seasonal Variation in the Gonadotropin-Releasing Hormone Response to Kisspeptin in Sheep: Possible Kisspeptin Regulation of the Kisspeptin Receptor

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Long-Term Recordings of Networks of Immortalized GnRH Neurons Reveal Episodic Patterns of Electrical Activity

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Kisspeptin‐Immunoreactivity Changes in a Sex‐ and Hypothalamic‐Region‐Specific Manner Across Rat Postnatal Development

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Kisspeptin expression in guinea pig hypothalamus: Effects of 17β‐estradiol

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Cancer Metastasis–Suppressing Peptide Metastin Upregulates Excitatory Synaptic Transmission in Hippocampal Dentate Granule Cells

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Gonadal Steroid Induction of Kisspeptin Peptide Expression in the Rostral Periventricular Area of the Third Ventricle During Postnatal Development in the Male Mouse

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Factors that regulate KiSS1 gene expression in the hippocampus

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Characterization of the porcine Kisspeptins receptor gene and evaluation as candidate for timing of puberty in sows

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GnRH Perikarya in Medial Basal Hypothalamus of Pubertal Female Rhesus Macaque are Ensheathed With Glia

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Kiss of the Mutant Mouse: How Genetically Altered Mice Advanced Our Understanding of Kisspeptin's Role in Reproductive Physiology

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Dynamics of gonadotropin-releasing hormone release during a pulse.

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Control of puberty onset and fertility by gonadotropin-releasing hormone neurons

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Definition of the hypothalamic GnRH pulse generator in mice

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Modulation of body temperature and LH secretion by hypothalamic KNDy (kisspeptin, neurokinin B and dynorphin) neurons: A novel hypothesis on the mechanism of hot flushes

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Emerging insights into hypothalamic‐pituitary‐gonadal axis regulation and interaction with stress signalling

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Bisphenol A: an emerging threat to female fertility

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The Gonadotropin-Releasing Hormone Pulse Generator

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Kisspeptin, Neurokinin B, and Dynorphin Act in the Arcuate Nucleus to Control Activity of the GnRH Pulse Generator in Ewes

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Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity

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KNDy Cells Revisited

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Conditional Viral Tract Tracing Delineates the Projections of the Distinct Kisspeptin Neuron Populations to Gonadotropin-Releasing Hormone (GnRH) Neurons in the Mouse

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Hypothalamo-Pituitary axis and puberty

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Role of core circadian clock genes in hormone release and target tissue sensitivity in the reproductive axis

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Optogenetic Stimulation of Arcuate Nucleus Kiss1 Neurons Reveals a Steroid-Dependent Glutamatergic Input to POMC and AgRP Neurons in Male Mice

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Delayed Puberty—Phenotypic Diversity, Molecular Genetic Mechanisms, and Recent Discoveries

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Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain

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