Fatty Acids from Lipids of Marine Organisms: Molecular Biodiversity, Roles as Biomarkers, Biologically Active Compounds, and Economical Aspects

The importance of the ratio of omega-6/omega-3 essential fatty acids

Simopoulos, A. P. (2002) · Biomedicine & Pharmacotherapy · doi:10.1016/s0753-3322(02)00253-6 · Cited by 4,131

Escherichia coli and Salmonella typhimurium: Cellular and molecular biology

Lejeune, P. (1988) · Biochimie · doi:10.1016/0300-9084(88)90119-8 · Cited by 4,072

Effect of aquaculture on world fish supplies.

Naylor, R. L., Goldburg, R. J., Primavera, J. H., Kautsky, N., Beveridge, M. C. M., Clay, J., Folke, C., Lubchenco, J., Mooney, H., & Troell, M. (2000) · Nature · doi:10.1038/35016500 · Cited by 3,063

Impact of Culture-Independent Studies on the Emerging Phylogenetic View of Bacterial Diversity

Hugenholtz, P., Goebel, B. M., & Pace, N. R. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.18.4765-4774.1998 · Cited by 2,428

Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease

de Lorgeril, M., Renaud, S., Salen, P., Monjaud, I., Mamelle, N., Martin, J. L., Guidollet, J., Touboul, P., & Delaye, J. (1994) · The Lancet · doi:10.1016/s0140-6736(94)92580-1 · Cited by 2,122

AHA Dietary Guidelines: Revision 2000: A Statement for Healthcare Professionals From the Nutrition Committee of the American Heart Association

Krauss, R. M., Eckel, R. H., Howard, B., Appel, L. J., Daniels, S. R., Deckelbaum, R. J., Erdman, J. W., Kris-Etherton, P., Goldberg, I. J., Kotchen, T. A., et al. (2000) · Circulation · doi:10.1161/01.cir.102.18.2284 · Cited by 1,458

Biochemistry of Lipids, Lipoproteins and Membranes

(2021) · Elsevier eBooks · doi:10.1016/c2020-0-00089-7 · Cited by 1,400

Importance of n−3 fatty acids in health and disease

Connor, W. E. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.1.171s · Cited by 1,344

Early Protection Against Sudden Death by n-3 Polyunsaturated Fatty Acids After Myocardial Infarction: Time-Course Analysis of the Results of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico (GISSI)-Prevenzione

Marchioli, R., Barzi, F., Bomba, E., Chieffo, C., Di Gregorio, D., Di Mascio, R., Franzosi, M. G., Geraci, E., Levantesi, G., Maggioni, A. P., et al. (2002) · Circulation · doi:10.1161/01.cir.0000014682.14181.f2 · Cited by 1,311

Microalgal biomarkers: A review of recent research developments

Volkman, J. K., Barrett, S. M., Blackburn, S. I., Mansour, M. P., Sikes, E. L., & Gelin, F. (1998) · Organic Geochemistry · doi:10.1016/s0146-6380(98)00062-x · Cited by 1,255

Systema Porifera. A Guide to the Classification of Sponges

Hooper, J. N. A., & Van Soest, R. W. M. (2002) · Systema Porifera · doi:10.1007/978-1-4615-0747-5_1 · Cited by 1,188

Blood Levels of Long-Chain n–3 Fatty Acids and the Risk of Sudden Death

Albert, C. M., Campos, H., Stampfer, M. J., Ridker, P. M., Manson, J. E., Willett, W. C., & Ma, J. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012918 · Cited by 1,146

Fish and Omega-3 Fatty Acid Intake and Risk of Coronary Heart Disease in Women

Hu, F. B. (2002) · JAMA · doi:10.1001/jama.287.14.1815 · Cited by 1,018

Fish Consumption and Risk of Sudden Cardiac Death

Albert, C. M. (1998) · JAMA · doi:10.1001/jama.279.1.23 · Cited by 990

Handbook of lipid research

Hanahan, D. J. (1978) · Plenum Press eBooks · Cited by 976

Broodstock management and egg and larval quality

Hardy, R. W. (1996) · Aquaculture · doi:10.1016/0044-8486(96)85211-2 · Cited by 965

DESATURATION AND RELATED MODIFICATIONS OF FATTY ACIDS

Shanklin, J., & Cahoon, E. B. (1998) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.49.1.611 · Cited by 916

Metabolism of highly unsaturated n-3 and n-6 fatty acids

Sprecher, H. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/s1388-1981(00)00077-9 · Cited by 868

Income inequality and population health

Mackenbach, J. P. (2002) · BMJ · doi:10.1136/bmj.324.7328.1 · Cited by 845

Omega 3 Fatty Acids in Bipolar Disorder: A Preliminary Double-blind, Placebo-Controlled Trial

Stoll, A. L., Severus, W. E., Freeman, M. P., Rueter, S., Zboyan, H. A., Diamond, E., Cress, K. K., & Marangell, L. B. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.5.407 · Cited by 814

A highly unsaturated fatty acid predicts carbon transfer between primary producers and consumers

Müller-Navarra, D. C., Brett, M. T., Liston, A. M., & Goldman, C. R. (2000) · Nature · doi:10.1038/47469 · Cited by 780

Production of polyunsaturated fatty acids by polyketide synthases in both prokaryotes and eukaryotes.

Metz, J. G., Roessler, P., Facciotti, D., Levering, C., Dittrich, F., Lassner, M., Valentine, R., Lardizabal, K., Domergue, F., Yamada, A., et al. (2001) · Science · doi:10.1126/science.1059593 · Cited by 760

Lipid analysis;: Isolation, separation, identification, and structural analysis of lipids

Christie, W. W. (1973) · Medical Entomology and Zoology · Cited by 753

Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: A randomised controlled trial

Thies, F., Garry, J. M., Yaqoob, P., Rerkasem, K., Williams, J., Shearman, C. P., Gallagher, P. J., Calder, P. C., & Grimble, R. F. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12468-3 · Cited by 739

Does fish oil lower blood pressure? A meta-analysis of controlled trials.

Morris, M. C., Sacks, F., & Rosner, B. (1993) · Circulation · doi:10.1161/01.cir.88.2.523 · Cited by 686

Cloning, Expression, and Nutritional Regulation of the Mammalian Δ-6 Desaturase

Cho, H. P., Nakamura, M. T., & Clarke, S. D. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.1.471 · Cited by 628

A Dose-Ranging Study of the Effects of Ethyl-Eicosapentaenoate in Patients With Ongoing Depression Despite Apparently Adequate Treatment With Standard Drugs

Peet, M., & Horrobin, D. F. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.10.913 · Cited by 614

Structure-Activity Relationship of .alpha.-Galactosylceramides against B16-Bearing Mice

Morita, M., Motoki, K., Akimoto, K., Natori, T., Sakai, T., Sawa, E., Yamaji, K., Koezuka, Y., Kobayashi, E., & Fukushima, H. (1995) · Journal of Medicinal Chemistry · doi:10.1021/jm00012a018 · Cited by 599

"Essential fatty acids" in aquatic ecosystems: a crucial link between diet and human health and evolution

Arts, M. T., Ackman, R. G., & Holub, B. J. (2001) · Canadian Journal of Fisheries and Aquatic Sciences · doi:10.1139/cjfas-58-1-122 · Cited by 580

Essential Fatty Acids

Aaes-Jørgensen, E. (1961) · Physiological Reviews · doi:10.1152/physrev.1961.41.1.1 · Cited by 558

Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid

Schmidt, A., Wolde, M., Thiele, C., Fest, W., Kratzin, H., Podtelejnikov, A. V., Witke, W., Huttner, W. B., & Söling, H.-D. (1999) · Nature · doi:10.1038/43613 · Cited by 533

Fatty acid analysis of blood plasma of patients with alzheimer's disease, other types of dementia, and cognitive impairment

Conquer, J. A., Tierney, M. C., Zecevic, J., Bettger, W. J., & Fisher, R. H. (2000) · Lipids · doi:10.1007/s11745-000-0646-3 · Cited by 524

Marine biogenic lipids, fats, and oils

ACKMAN, R. G. (1989) · CRC Press eBooks · Cited by 520

Intake of Fish and Omega-3 Fatty Acids and Risk of Stroke in Women

Iso, H. (2001) · JAMA · doi:10.1001/jama.285.3.304 · Cited by 481

Search and Discovery Strategies for Biotechnology: the Paradigm Shift

Bull, A. T., Ward, A. C., & Goodfellow, M. (2000) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.64.3.573-606.2000 · Cited by 477

Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients

Edwards, R. (1998) · Journal of Affective Disorders · doi:10.1016/s0165-0327(97)00166-3 · Cited by 470

Lipid Biochemistry: An Introduction

Gurr, M. I., & James, A. T. (1980) · Springer eBooks · doi:10.1007/978-94-009-5907-1 · Cited by 460

The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer

Barber, M. D., Ross, J. A., Voss, A. C., Tisdale, M. J., & Fearon, K. C. H. (1999) · British Journal of Cancer · doi:10.1038/sj.bjc.6690654 · Cited by 459

Essential fatty acid metabolism in boys with attention-deficit hyperactivity disorder

Stevens, L., Zentall, S., Deck, J., Abate, M., Watkins, B., Lipp, Sr., & Burgess, Jr. (1995) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/62.4.761 · Cited by 445

Enhancement of chilling tolerance of a cyanobacterium by genetic manipulation of fatty acid desaturation

Wada, H., Combos, Z., & Murata, N. (1990) · Nature · doi:10.1038/347200a0 · Cited by 406

Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans

Watts, J. L., & Browse, J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092064799 · Cited by 402

Fatty acids from 28 marine microalgae

Viso, A.-C., & Marty, J.-C. (1993) · Phytochemistry · doi:10.1016/s0031-9422(00)90839-2 · Cited by 400

Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus

Natori, T., Morita, M., Akimoto, K., & Koezuka, Y. (1994) · Tetrahedron · doi:10.1016/s0040-4020(01)86991-x · Cited by 397

n−3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study

Lemaitre, R. N., King, I. B., Mozaffarian, D., Kuller, L. H., Tracy, R. P., & Siscovick, D. S. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.2.319 · Cited by 393

Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia

Goodfellow, J., Bellamy, M. F., Ramsey, M. W., Jones, C. J. H., & Lewis, M. J. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(99)00548-3 · Cited by 380

Polyunsaturated fatty acid synthesis: What will they think of next?

Wallis, J. G., Watts, J. L., & Browse, J. (2002) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(02)02168-0 · Cited by 375

Cognitive decline and fatty acid composition of erythrocyte membranes—The EVA Study

Heude, B., Ducimetière, P., & Berr, C. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.4.803 · Cited by 363

KRN7000, a novel immunomodulator, and its antitumor activities.

Kobayashi, E., Motoki, K., Uchida, T., Fukushima, H., & Koezuka, Y. (1995) · PubMed · Cited by 361

Consumption of oily fish and childhood asthma risk

Hodge, L., Salome, C. M., Peat, J. K., Haby, M. M., Xuan, W., & Woolcock, A. J. (1996) · Medical Journal of Australia · doi:10.5694/j.1326-5377.1996.tb122010.x · Cited by 361

Low consumption of seafood in early pregnancy as a risk factor for preterm delivery: prospective cohort study

Olsen, S. F. (2002) · BMJ · doi:10.1136/bmj.324.7335.447 · Cited by 360

Systema Porifera

(2002) · Springer eBooks · doi:10.1007/978-1-4615-0747-5 · Cited by 352

Optimization of docosahexaenoic acid production by Schizochytrium limacinum SR21

Yokochi, T., Honda, D., Higashihara, T., & Nakahara, T. (1998) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051139 · Cited by 350

Fatty acid desaturation and chain elongation in eukaryotes

Cook, H. W. (1996) · New Comprehensive Biochemistry · doi:10.1016/s0167-7306(08)60512-8 · Cited by 344

Heterotrophic production of long chain omega-3 fatty acids utilizing algae and algae-like microorganisms

Barclay, W. R., Meager, K. M., & Abril, J. R. (1994) · Journal of Applied Phycology · doi:10.1007/bf02186066 · Cited by 337

Biochemical Function and Ecological Significance of Novel Bacterial Lipids in Deep-Sea Procaryotes

DeLong, E. F., & Yayanos, A. A. (1986) · Applied and Environmental Microbiology · doi:10.1128/aem.51.4.730-737.1986 · Cited by 336

Fish Consumption and Risk of Stroke in Men

He, K. (2002) · JAMA · doi:10.1001/jama.288.24.3130 · Cited by 334

Biosynthesis and regulation of microbial polyunsaturated fatty acid production

Certik, M., & Shimizu, S. (1999) · Journal of Bioscience and Bioengineering · doi:10.1016/s1389-1723(99)80001-2 · Cited by 330

Lipids, trophic relationships, and biodiversity in Arctic and Antarctic krill

Falk‐Petersen, S., Hagen, W., Kattner, G., Clarke, A., & SARGENT, J. R. (2000) · Canadian Journal of Fisheries and Aquatic Sciences · doi:10.1139/cjfas-57-s3-178 · Cited by 329

The biological chemistry of marine copepods

(1988) · Comparative Biochemistry and Physiology Part A: Physiology · doi:10.1016/0300-9629(88)90857-2 · Cited by 324

Arabidopsis requires polyunsaturated lipids for low-temperature survival.

Miquel, M., James, D., Dooner, H., & Browse, J. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.13.6208 · Cited by 318

Mutants of Arabidopsis reveal many roles for membrane lipids

Wallis, J. G., & Browse, J. (2002) · Progress in Lipid Research · doi:10.1016/s0163-7827(01)00027-3 · Cited by 317

Recent advances in the biochemistry and molecular biology of fatty acyl desaturases

Tocher, D. R., Leaver, M. J., & Hodgson, P. A. (1998) · Progress in Lipid Research · doi:10.1016/s0163-7827(98)00005-8 · Cited by 312

Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: A randomized control trial

Gogos, C. A., Ginopoulos, P., Salsa, B., Apostolidou, E., Zoumbos, N. C., & Kalfarentzos, F. (1998) · Cancer · doi:10.1002/(sici)1097-0142(19980115)82:2<403::aid-cncr21>3.0.co;2-1 · Cited by 311

n−3 Fatty acid supplements in rheumatoid arthritis

Kremer, J. M. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.1.349s · Cited by 303

Lipid biogeochemistry of plankton, settling matter and sediments in Trinity Bay, Newfoundland. II. Fatty acids

Budge, S. M., & Parrish, C. C. (1998) · Organic Geochemistry · doi:10.1016/s0146-6380(98)00177-6 · Cited by 302

The biological chemistry of marine copepods

(1988) · International Journal of Biochemistry · doi:10.1016/0020-711x(88)90083-3 · Cited by 299

Does Supplementation of Diet With 'Fish Oil' Reduce Blood Pressure?: A Meta-analysis of Controlled Clinical Trials

Appel, L. J. (1993) · Archives of Internal Medicine · doi:10.1001/archinte.1993.00410120017003 · Cited by 298

Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects

Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. B., Watts, G. F., & Beilin, L. J. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.5.817 · Cited by 296

Seasonal Changes in Lipid Composition of Sardine ( Sardina pilchardus )

BANDARRA, N. M., BATISTA, I., NUNES, M. L., EMPIS, J. M., & CHRISTIE, W. W. (1997) · Journal of Food Science · doi:10.1111/j.1365-2621.1997.tb04364.x · Cited by 286

Polyunsaturated fatty acids in marine bacteria — a dogma rewritten

Russell, N. J., & Nichols, D. S. (1999) · Microbiology · doi:10.1099/13500872-145-4-767 · Cited by 286

A triclosan-resistant bacterial enzyme

Heath, R. J., & Rock, C. O. (2000) · Nature · doi:10.1038/35018162 · Cited by 284

Fatty fish consumption and risk of prostate cancer

Terry, P., Lichtenstein, P., Feychting, M., Ahlbom, A., & Wolk, A. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04889-3 · Cited by 284

A chain initiation factor common to both modular and aromatic polyketide synthases

Bisang, C., Long, P. F., Corte´s, J., Westcott, J., Crosby, J., Matharu, A.-L., Cox, R. J., Simpson, T. J., Staunton, J., & Leadlay, P. F. (1999) · Nature · doi:10.1038/46829 · Cited by 278

Expression of a borage desaturase cDNA containing an N-terminal cytochrome b 5 domain results in the accumulation of high levels of Δ 6 -desaturated fatty acids in transgenic tobacco

Sayanova, O., Smith, M. A., Lapinskas, P., Stobart, A. K., Dobson, G., Christie, W. W., Shewry, P. R., & Napier, J. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.8.4211 · Cited by 276

Development of farmed fish: a nutritionally necessary alternative to meat

Sargent, J. R., & Tacon, A. G. J. (1999) · Proceedings of the Nutrition Society · doi:10.1017/s0029665199001366 · Cited by 276

Fish Consumption, Depression, and Suicidality in a General Population

Tanskanen, A., Hibbeln, J. R., Hintikka, J., Haatainen, K., Honkalampi, K., & Viinamäki, H. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.5.512 · Cited by 275

N‐3 and N‐6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case‐control study in Tours, France

Maillard, V., Bougnoux, P., Ferrari, P., Jourdan, M., Pinault, M., Lavillonnière, F., Body, G., Le Floch, O., & Chajès, V. (2002) · International Journal of Cancer · doi:10.1002/ijc.10130 · Cited by 271

Reduced asthma symptoms with n-3 fatty acid ingestion are related to 5-series leukotriene production

Broughton, K., Johnson, C., Pace, B., Liebman, M., & Kleppinger, K. (1997) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/65.4.1011 · Cited by 270

Fish Consumption and Coronary Heart Disease Mortality in Finland, Italy, and the Netherlands

Oomen, C. M., Feskens, E. J. M., R s nen, L., Fidanza, F., Nissinen, A. M., Menotti, A., Kok, F. J., & Kromhout, D. (2000) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a010144 · Cited by 269

Fatty Acids of Marine Algae from the Pacific Coast of North California

Khotimchenko, S. V., Vaskovsky, V. E., & Titlyanova, T. V. (2002) · Botanica Marina · doi:10.1515/bot.2002.003 · Cited by 257

Recent advances in the study of fatty acid desaturases from animals and lower eukaryotes

Pereira, S. L., Leonard, A. E., & Mukerji, P. (2003) · Prostaglandins, Leukotrienes and Essential Fatty Acids · doi:10.1016/s0952-3278(02)00259-4 · Cited by 256

Shewanella gelidimarina sp. nov. and Shewanella frigidimarina sp. nov., Novel Antarctic Species with the Ability To Produce Eicosapentaenoic Acid (20:5 3) and Grow Anaerobically by Dissimilatory Fe(III) Reduction

Bowman, J. P., McCammon, S. A., Nichols, D. S., Skerratt, J. H., Rea, S. M., Nichols, P. D., & McMeekin, T. A. (1997) · International Journal of Systematic Bacteriology · doi:10.1099/00207713-47-4-1040 · Cited by 254

Problems with essential fatty acids: time for a new paradigm?

Cunnane, S. C. (2003) · Progress in Lipid Research · doi:10.1016/s0163-7827(03)00038-9 · Cited by 249

Clinical Characteristics and Serum Essential Fatty Acid Levels in Hyperactive Children

Mitchell, E. A., Aman, M. G., Turbott, S. H., & Manku, M. (1987) · Clinical Pediatrics · doi:10.1177/000992288702600805 · Cited by 246

The Biotechnological Potential of Thraustochytrids

Lewis, T. E., Nichols, P. D., & McMeekin, T. A. (1999) · Marine Biotechnology · doi:10.1007/pl00011813 · Cited by 245

Antioxidants and fatty acids in the amelioration of rheumatoid arthritis and related disorders

Darlington, L. G., & Stone, T. W. (2001) · British Journal of Nutrition · doi:10.1079/bjn2000239 · Cited by 245

Effects of Dietary Fish and Weight Reduction on Ambulatory Blood Pressure in Overweight Hypertensives

Bao, D. Q., Mori, T. A., Burke, V., Puddey, I. B., & Beilin, L. J. (1998) · Hypertension · doi:10.1161/01.hyp.32.4.710 · Cited by 241

Monounsaturated but Not Polyunsaturated Fatty Acids Are Required for Growth of the Deep-Sea Bacterium Photobacterium profundum SS9 at High Pressure and Low Temperature

Allen, E. E., Facciotti, D., & Bartlett, D. H. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.4.1710-1720.1999 · Cited by 240

Dietary n-3 fatty acids and therapy for rheumatoid arthritis

James, M. J., Cleland, L. G., & James, M. J. (1997) · Seminars in Arthritis and Rheumatism · doi:10.1016/s0049-0172(97)80009-1 · Cited by 237

The effect of dietary lipid on polyunsaturated fatty acid metabolism in Atlantic salmon (Salmo salar) undergoing parr‐smolt transformation

Bell, J. G., Tocher, D. R., Farndale, B. M., Cox, D. I., McKinney, R. W., & Sargent, J. R. (1997) · Lipids · doi:10.1007/s11745-997-0066-4 · Cited by 236

BIODIVERSITY AS A SOURCE OF INNOVATION IN BIOTECHNOLOGY

Bull, A. T., Goodfellow, M., & Slater, J. H. (1992) · Annual Review of Microbiology · doi:10.1146/annurev.mi.46.100192.001251 · Cited by 233

Trophic transfer of fatty acids, sterols, and a triterpenoid alcohol between bacteria, a ciliate, and the copepod Acartia tonsa

Ederington, M. C., McManus, G. B., & Harvey, H. R. (1995) · Limnology and Oceanography · doi:10.4319/lo.1995.40.5.0860 · Cited by 229

THE FATTY ACID AND STEROL COMPOSITION OF FIVE MARINE DINOFLAGELLATES

Mansour, M. P., Volkman, J. K., Jackson, A. E., & Blackburn, S. I. (1999) · Journal of Phycology · doi:10.1046/j.1529-8817.1999.3540710.x · Cited by 228

Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder

Burgess, J. R., Stevens, L., Zhang, W., & Peck, L. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.1.327s · Cited by 222

Identification of an animal ω-3 fatty acid desaturase by heterologous expression in Arabidopsis

Spychalla, J. P., Kinney, A. J., & Browse, J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.4.1142 · Cited by 222

Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids

Leonard, A. E., BOBIK, E. G., DORADO, J., Kroeger, P. E., Chuang, L., Thurmond, J. M., PARKER-BARNES, J. M., Das, T., Huang, Y. S., & Mukerji, P. (2000) · Biochemical Journal · doi:10.1042/0264-6021:3500765 · Cited by 220

Modulation of ion channels by arachidonic acid

MEVES, H. (1994) · Progress in Neurobiology · doi:10.1016/0301-0082(94)90012-4 · Cited by 209

Identification of the peroxisomal β-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid

Ferdinandusse, S., Denis, S., Mooijer, P. A. W., Zhang, Z., Reddy, J. K., Spector, A. A., & Wanders, R. J. A. (2001) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)31527-3 · Cited by 208

Effect of docosahexaenoic acid supplementation of lactating women on the fatty acid composition of breast milk lipids and maternal and infant plasma phospholipids

Jensen, C. L., Maude, M., Anderson, R. E., & Heird, W. C. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.1.292s · Cited by 207

Prostate cancer risk and consumption of fish oils: A dietary biomarker-based case–control study

Norrish, A. E., Skeaff, C. M., Arribas, G. L. B., Sharpe, S. J., & Jackson, R. T. (1999) · British Journal of Cancer · doi:10.1038/sj.bjc.6690835 · Cited by 204

Fatty acids from 11 marine macroalgae of the French Brittany coast

Fleurence, J., Gutbier, G., Mabeau, S., & Leray, C. (1994) · Journal of Applied Phycology · doi:10.1007/bf02182406 · Cited by 203

Production of eicosapentaenoic acid from marine bacteria

Yazawa, K. (1996) · Lipids · doi:10.1007/bf02637095 · Cited by 202

Production of high yields of docosahexaenoic acid by Schizochytrium sp. strain SR21

Yaguchi, T., Tanaka, S., Yokochi, T., Nakahara, T., & Higashihara, T. (1997) · Journal of the American Oil Chemists' Society · doi:10.1007/s11746-997-0249-z · Cited by 200

Identification of a novel D6‐acyl‐group desaturase by targeted gene disruption in Physcomitrella patens

Girke, T., Schmidt, H., Zähringer, U., Reski, R., & Heinz, E. (1998) · The Plant Journal · doi:10.1046/j.1365-313x.1998.00178.x · Cited by 200

Psychroflexus torquis gen. nov., sp. nov. a psychrophilic species from Antarctic sea ice, and reclassification of Flavobacterium gondwanense (Dobson et al. 1993) as Psychroflexus gondwanense gen. nov., comb. nov.

Bowman, J. P., McCammon, S. A., Lewis, T., Skerratt, J. H., Brown, J. L., Nichols, D. S., & McMeekin, T. A. (1998) · Microbiology · doi:10.1099/00221287-144-6-1601 · Cited by 196

Biosynthesis of Unsaturated Fatty Acids in Microorganisms: Structure and biosynthetic pathways are compared and related to physiological properties of the organisms.

Erwin, J., & Bloch, K. (1964) · Science · doi:10.1126/science.143.3610.1006 · Cited by 194

Bioactive fatty acids: role in bone biology and bone cell function

Watkins, B. (2001) · Progress in Lipid Research · doi:10.1016/s0163-7827(00)00016-3 · Cited by 188

The gas chromatograph in practical analyses of common and uncommon fatty acids for the 21st century

Ackman, R. G. (2002) · Analytica Chimica Acta · doi:10.1016/s0003-2670(02)00098-3 · Cited by 187

Lipids and fatty acids in ice algae and phytoplankton from the Marginal Ice Zone in the Barents Sea

Falk-Petersen, S., Sargent, J. R., Henderson, J., Hegseth, E. N., Hop, H., & Okolodkov, Y. B. (1998) · Polar Biology · doi:10.1007/s003000050274 · Cited by 186

Docosahexaenoic acid transfer into human milk after dietary supplementation: a randomized clinical trial

Fidler, N., Sauerwald, T., Pohl, A., Demmelmair, H., & Koletzko, B. (2000) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)33449-0 · Cited by 184

Fatty acid composition of phytoplankton, settling particulate matter and sediments at a sheltered bivalve aquaculture site

Budge, S. M., Parrish, C. C., & Mckenzie, C. H. (2001) · Marine Chemistry · doi:10.1016/s0304-4203(01)00068-8 · Cited by 182

Fatty acid composition of Arctic and Antarctic macroalgae: indicator of phylogenetic and trophic relationships

Graeve, M., Kattner, G., Wiencke, C., & Karsten, U. (2002) · Marine Ecology Progress Series · doi:10.3354/meps231067 · Cited by 181

Production of docosahexaenoic and docosapentaenoic acids by Schizochytrium sp. isolated from Yap Islands

Nakahara, T., Yokochi, T., Higashihara, T., Tanaka, S., Yaguchi, T., & Honda, D. (1996) · Journal of the American Oil Chemists' Society · doi:10.1007/bf02523506 · Cited by 181

Efficacy of fish oil concentrate in the treatment of rheumatoid arthritis.

Volker, D., FitzGerald, P. E. B., Major, G., & Garg, M. L. (2000) · PubMed · Cited by 177

Identification and characterization of an enzyme involved in the elongation of n-6 and n-3 polyunsaturated fatty acids

Parker-Barnes, J. M., Das, T., Bobik, E., Leonard, A. E., Thurmond, J. M., Chaung, L.-T., Huang, Y.-S., & Mukerji, P. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.15.8284 · Cited by 177

Evaluation of fatty acids as biomarkers for a natural plankton community. A field study of a spring bloom and a post-bloom period off West Greenland

N., R., & L., P. (2002) · Marine Biology · doi:10.1007/s00227-002-0841-6 · Cited by 173

Fatty acids as trophic markers of phytoplankton blooms in the Bahía Blanca estuary (Buenos Aires, Argentina) and in Trinity Bay (Newfoundland, Canada)

Napolitano, G. E., Pollero, R. J., Gayoso, A. M., Macdonald, B. A., & Thompson, R. J. (1997) · Biochemical Systematics and Ecology · doi:10.1016/s0305-1978(97)00053-7 · Cited by 172

Single cell oils — have they a biotechnological future?

Ratledge, C. (1993) · Trends in Biotechnology · doi:10.1016/0167-7799(93)90015-2 · Cited by 172

Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid

Moore, S. A., Hurt, E., Yoder, E., Sprecher, H., & Spector, A. A. (1995) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39724-8 · Cited by 170

Lipids and life strategies of Calanus finmarchicus , Calanus glacialis and Calanus hyperboreus in late autumn, Kongsfjorden, Svalbard

Scott, C. L., Kwasniewski, S., Falk-Petersen, S., & Sargent, J. R. (2000) · Polar Biology · doi:10.1007/s003000000114 · Cited by 168

Natural halogenated fatty acids: their analogues and derivatives

Dembitsky, V. M., & Srebnik, M. (2002) · Progress in Lipid Research · doi:10.1016/s0163-7827(02)00003-6 · Cited by 168

Photobacterium profundum sp. nov., a new, moderately barophilic bacterial species isolated from a deep-sea sediment

Nogi, Y., Masui, N., & Kato, C. (1998) · Extremophiles · doi:10.1007/s007920050036 · Cited by 166

Optimization of production of docosahexaenoic acid (DHA) by Thraustochytrium aureum ATCC 34304

Bajpai, P. K., Bajpai, P., & Ward, O. P. (1991) · Journal of the American Oil Chemists' Society · doi:10.1007/bf02663823 · Cited by 163

Nutritional Enhancement of n‐3 and n‐6 Fatty Acids in Rotifers and Artemia Nauplii by Feeding Spray‐dried Schizochytrium sp.

Barclay, W., & Zeller, S. (1996) · Journal of the World Aquaculture Society · doi:10.1111/j.1749-7345.1996.tb00614.x · Cited by 163

Isolation of a Δ5-Fatty Acid Desaturase Gene fromMortierella alpina

Michaelson, L. V., Lazarus, C. M., Griffiths, G., Napier, J. A., & Stobart, A. K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.30.19055 · Cited by 161

Effects of n-3 Polyunsaturated Fatty Acids on Glucose Homeostasis and Blood Pressure in Essential Hypertension: A Randomized, Controlled Trial

Toft, I., Bonaa, K. H., Ingebretsen, O. C., Nordoy, A., & Jenssen, T. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-123-12-199512150-00003 · Cited by 159

α-Galactosylceramide (KRN7000) suppression of chemical- and oncogene-dependent carcinogenesis

Hayakawa, Y., Rovero, S., Forni, G., & Smyth, M. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1630663100 · Cited by 158

Composition of lipids, fatty acids and sterols in Okinawan corals

Yamashiro, H., Oku, H., Higa, H., Chinen, I., & Sakai, K. (1999) · Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology · doi:10.1016/s0305-0491(99)00014-0 · Cited by 158

Marine n-3 Fatty Acids, Wine Intake, and Heart Rate Variability in Patients Referred for Coronary Angiography

Christensen, J. H., Skou, H. A., Fog, L., Hansen, V. E., Vesterlund, T., Dyerberg, J., Toft, E., & Schmidt, E. B. (2001) · Circulation · doi:10.1161/01.cir.103.5.651 · Cited by 158

Cloning of Δ12‐ and Δ6‐desaturases from Mortierella alpina and recombinant production of γ‐linolenic acid in Saccharomyces cerevisiae

Huang, Y., Chaudhary, S., Thurmond, J. M., Bobik, E. G., Yuan, L., Chan, G. M., Kirchner, S. J., Mukerji, P., & Knutzon, D. S. (1999) · Lipids · doi:10.1007/s11745-999-0410-8 · Cited by 158

Heterologous reconstitution in yeast of the polyunsaturated fatty acid biosynthetic pathway

Beaudoin, F., Michaelson, L. V., Hey, S. J., Lewis, M. J., Shewry, P. R., Sayanova, O. V., & Napier, J. A. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.110140197 · Cited by 155

Increased docosahexaenoic acid levels in human newborn infants by administration of sardines and fish oil during pregnancy

Connor, W. E., Lowensohn, R. I., & Hatcher, L. F. (1996) · Lipids · doi:10.1007/bf02637073 · Cited by 155

Thraustochytrids are chromists, not Fungi: 18s rRNA signatures of Heterokonta

Cavalier‐Smith, T., Allsopp, M. T. E. P., & Chao, E. E. (1994) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1994.0156 · Cited by 154

Comparison of the lipid class and fatty acid composition between a reproductive cycle in nature and a standard hatchery conditioning of the Pacific Oyster Crassostrea gigas

Soudant, P., Ryckeghem, K. V., Marty, Y., Moal, J., Samain, J. F., & Sorgeloos, P. (1999) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s0305-0491(99)00063-2 · Cited by 152

Shewanella frigidimarina and Shewanella livingstonensis sp. nov. isolated from Antarctic coastal areas.

Bozal, N., Montes, M. J., Tudela, E., Jiménez, F., & Guinea, J. (2002) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-52-1-195 · Cited by 149

Schizochytrium limacinum sp. nov., a new thraustochytrid from a mangrove area in the west Pacific Ocean

Honda, D., Yokochi, T., Nakahara, T., Erata, M., & Higashihara, T. (1998) · Mycological Research · doi:10.1017/s0953756297005170 · Cited by 149

Long-chain polyunsaturated fatty acid requirements during pregnancy and lactation

Makrides, M., & Gibson, R. A. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.1.307s · Cited by 148

ω-3 Fatty acid–based lipid infusion in patients with chronic plaque psoriasis: Results of a double-blind, randomized, placebo-controlled, multicenter trial

Mayser, P. A., Mrowietz, U., Arenberger, P., Barták, P., Buchvald, J., Christophers, E., Jabłońska, S., Salmhofer, W., Schill, W., Krämer, H., et al. (1998) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(98)70114-8 · Cited by 148

Fatty acids of some algae from the Bohai Sea

Li, X., Fan, X., Han, L., & Lou, Q. (2002) · Phytochemistry · doi:10.1016/s0031-9422(01)00437-x · Cited by 148

Identification of Δ5-Desaturase from Mortierella alpina by Heterologous Expression in Bakers' Yeast and Canola

Knutzon, D. S., Thurmond, J. M., Huang, Y. S., Chaudhary, S., BOBIK, E. G., Chan, G. M., Kirchner, S. J., & Mukerji, P. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.45.29360 · Cited by 144

Reassessment of lipid composition of the diatom, Skeletonema costatum

Bergé, J. P. (1995) · Phytochemistry · doi:10.1016/0031-9422(94)00156-n · Cited by 144

Krill-copepod interactions at South Georgia, Antarctica, I. Omnivory by Euphausia superba

Atkinson, A., & Snÿder, R. (1997) · Marine Ecology Progress Series · doi:10.3354/meps160063 · Cited by 143

Identification of a Caenorhabditis elegans Δ6-fatty-acid-desaturase by heterologous expression in Saccharomyces cerevisiae

Napier, J. A., HEY, J. S., LACEY, J. D., & SHEWRY, R. P. (1998) · Biochemical Journal · doi:10.1042/bj3300611 · Cited by 142

Fish Consumption Is Associated With Lower Heart Rates

Dallongeville, J., Yarnell, J., Ducimetière, P., Arveiler, D., Ferrières, J., Montaye, M., Luc, G., Evans, A., Bingham, A., Hass, B., et al. (2003) · Circulation · doi:10.1161/01.cir.0000084542.64687.97 · Cited by 141

Low serum docosahexaenoic acid is a significant risk factor for alzheimer's dementia

Kyle, D. J., Schaefer, E. J., Patton, G. M., & Beiser, A. (1999) · Lipids · doi:10.1007/bf02562306 · Cited by 140

Bioactive Compounds from Natural Sources

Tringali, C. (2000) · CRC Press eBooks · doi:10.1201/9781482289268 · Cited by 140

Identification of a cDNA encoding a novel C18‐Δ9 polyunsaturated fatty acid‐specific elongating activity from the docosahexaenoic acid (DHA)‐producing microalga, Isochrysis galbana1

Qi, B., Beaudoin, F., Fraser, T. C. M., Stobart, A. K., Napier, J. A., & Lazarus, C. M. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03247-1 · Cited by 138

Sources of essential fatty acids in the marine microbial loop

Zhukova, N. V., & Kharlamenko, V. (1999) · Aquatic Microbial Ecology · doi:10.3354/ame017153 · Cited by 137

C-reactive protein, dietary n-3 fatty acids, and the extent of coronary artery disease

Madsen, T., Skou, H. A., Hansen, V. E., Fog, L., Christensen, J. H., Toft, E. S., & Schmidt, E. B. (2001) · The American Journal of Cardiology · doi:10.1016/s0002-9149(01)02049-5 · Cited by 137

Lipid, FA, and sterol composition of New Zealand green lipped mussel (Perna canaliculus) and tasmanian blue mussel (Mytilus edulis)

Murphy, K. J., Mooney, B. D., Mann, N. J., et al. (2002) · Lipids · doi:10.1007/s11745-002-0937-8 · Cited by 132

The Δ8-Desaturase ofEuglena gracilis:An Alternate Pathway for Synthesis of 20-Carbon Polyunsaturated Fatty Acids

Wallis, J. G., & Browse, J. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1999.1167 · Cited by 132

Efficacy of n‐3 polyunsaturated fatty acids after myocardial infarction: Results of GISSI‐prevenzione trial

Marchioli, R., Schweiger, C., Tavazzi, L., & Valagussa, F. (2001) · Lipids · doi:10.1007/s11745-001-0694-8 · Cited by 131

Phylogenetic characterization of epibiotic bacteria in the accessory nidamental gland and egg capsules of the squid Loligo pealei (Cephalopoda: Loliginidae)

Barbieri, E., Paster, B. J., Hughes, D., Žůrek, L., Moser, D. P., Teske, A., & Sogin, M. L. (2001) · Environmental Microbiology · doi:10.1046/j.1462-2920.2001.00172.x · Cited by 131

Developments with Antarctic microorganisms: culture collections, bioactivity screening, taxonomy, PUFA production and cold-adapted enzymes

Nichols, D. S., Bowman, J. P., Sanderson, K. R., Nichols, C. M., Lewis, T. E., McMeekin, T. A., & Nichols, P. D. (1999) · Current Opinion in Biotechnology · doi:10.1016/s0958-1669(99)80042-1 · Cited by 130

Effects of supplementation with fish oil–derived n−3 fatty acids and γ-linolenic acid on circulating plasma lipids and fatty acid profiles in women

Laidlaw, M., & Holub, B. J. (2003) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/77.1.37 · Cited by 130

Shewanella amazonensis sp. nov., a novel metal-reducing facultative anaerobe from Amazonian shelf muds

Venkateswaran, K. J., Dollhopf, M. E., Aller, R. C., Stackebrandt, E. S., & Nealson, K. (1998) · International Journal of Systematic Bacteriology · doi:10.1099/00207713-48-3-965 · Cited by 130

Polyunsaturated fatty acids in Antarctic bacteria

Nichols, D. S., Nichols, P. D., & McMeekin, T. A. (1993) · Antarctic Science · doi:10.1017/s0954102093000215 · Cited by 130

Activity of human Δ5 and Δ6 desaturases on multiple n‐3 and n‐6 polyunsaturated fatty acids

de Antueno, R. J., Knickle, L. C., Smith, H., Elliot, M. L., Allen, S. J., Nwaka, S., & Winther, M. D. (2001) · FEBS Letters · doi:10.1016/s0014-5793(01)03135-0 · Cited by 129

Lipids and trophic interactions of ice fauna and pelagic zooplankton in the marginal ice zone of the Barents Sea

Scott, C. L., Falk‐Petersen, S., SARGENT, J. R., et al. (1999) · Polar Biology · doi:10.1007/s003000050335 · Cited by 129

Essential fatty acids for larval mud crab Scylla serrata: implications of lack of the ability to bioconvert C18 unsaturated fatty acids to highly unsaturated fatty acids

Suprayudi, M. A., Takeuchi, T., & Hamasaki, K. (2003) · Aquaculture · doi:10.1016/s0044-8486(03)00542-8 · Cited by 127

The biology of marine fungi.

Moss, S. T. (1986) · Cited by 126

Highly unsaturated fatty acid requirements of Penaeus monodon postlarvae: an experimental approach based on Artemia enrichment

Rees, J. F., Curé, K., Piyatiratitivorakul, S., Sorgeloos, P., & Menasveta, P. (1994) · Aquaculture · doi:10.1016/0044-8486(94)90510-x · Cited by 125

Single point mutations affect fatty acid block of human myocardial sodium channel α subunit Na + channels

Xiao, Y., Ke, Q., Wang, S., Auktor, K., Yang, Y., Wang, G. K., Morgan, J. P., & Leaf, A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061003798 · Cited by 125

The same rat Δ6-desaturase not only acts on 18- but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis

d’Andrea, S., Guillou, H., Jan, S., Catheline, D., Thibault, J.-N., Bouriel, M., Rioux, V., & Legrand, P. (2002) · Biochemical Journal · doi:10.1042/bj3640049 · Cited by 124

Lipids and trophodynamics of Antarctic zooplankton

Phleger, C. F., Nichols, P. D., & Virtue, P. (1998) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s0305-0491(98)10020-2 · Cited by 123

Elucidation of the Biosynthesis of Eicosapentaenoic Acid in the Microalga Porphyridium cruentum (II. Studies with Radiolabeled Precursors)

Khozin‐Goldberg, I., Adlerstein, D., Bigongo, C., Heimer, Y. M., & Cohen, Z. (1997) · PLANT PHYSIOLOGY · doi:10.1104/pp.114.1.223 · Cited by 120

Phospholipids: Characterization, metabolism, and novel biological applications

SHAW, N. (1995) · Endeavour · doi:10.1016/0160-9327(95)90084-5 · Cited by 120

Role of polyunsaturated fatty acids in lung disease

Schwartz, J. D. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.1.393s · Cited by 119

Taxonomic studies of extremely barophilic bacteria isolated from the Mariana Trench and description of Moritella yayanosii sp. nov., a new barophilic bacterial isolate

Nogi, Y., & Kato, C. (1999) · Extremophiles · doi:10.1007/s007920050101 · Cited by 118

Characterization of Vibrio viscosus and Vibrio wodanis isolated at different geographical locations: a proposal for reclassification of Vibrio viscosus as Moritella viscosa comb. nov.

Benediktsdóttir, E., Verdonck, L., Spröer, C., Helgason, S., & Swings, J. (2000) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-50-2-479 · Cited by 117

Δ6-Fatty acid desaturase from an arachidonic acid-producing Mortierella fungus

Sakuradani, E., Kobayashi, M., & Shimizu, S. (1999) · Gene · doi:10.1016/s0378-1119(99)00359-5 · Cited by 114

Prokaryotes and the input of polyunsaturated fatty acids to the marine food web

Nichols, D. S. (2003) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(02)01200-4 · Cited by 113

Erratum: A triclosan-resistant bacterial enzyme

Heath, R. J., & Rock, C. O. (2000) · Nature · doi:10.1038/35022656 · Cited by 112

Lipids of Antarctic Ocean amphipods: food chain interactions and the occurrence of novel biomarkers

Nelson, M. M., Mooney, B. D., Nichols, P. D., & Phleger, C. F. (2001) · Marine Chemistry · doi:10.1016/s0304-4203(00)00072-4 · Cited by 112

Production of docosahexaenoic acid by Thraustochytrium aureum

Bajpai, P., Bajpai, P., & Ward, O. P. (1991) · Applied Microbiology and Biotechnology · doi:10.1007/bf00169881 · Cited by 112

Very-long-chain fatty acids from the animal and plant kingdoms

Řezanka, T. (1989) · Progress in Lipid Research · doi:10.1016/0163-7827(89)90011-8 · Cited by 111

Fatty acid profiles of Mytilus galloprovincialis (Lmk) mussel of subtidal and rocky shore origin

Freites, L. F., Fernández‐Reiriz, M. J., & Labarta, U. (2002) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/s1096-4959(02)00057-x · Cited by 107

Very-long-chain (C28) highly unsaturated fatty acids in marine dinoflagellates

Mansour, M. P., Volkman, J. K., Holdsworth, D. G., Jackson, A. E., & Blackburn, S. I. (1999) · Phytochemistry · doi:10.1016/s0031-9422(98)00564-0 · Cited by 104

Improvement of docosahexaenoic acid production in a culture of Thraustochytrium aureum by medium optimization

Iida, I., Nakahara, T., Yokochi, T., Kamisaka, Y., Yagi, H., Yamaoka, M., & Suzuki, O. (1996) · Journal of Fermentation and Bioengineering · doi:10.1016/0922-338x(96)83125-4 · Cited by 103

The role of cytochrome b5 fusion desaturases in the synthesis of polyunsaturated fatty acids

Napier, J. A., Michaelson, L. V., & Sayanova, O. V. (2003) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/s0952-3278(02)00263-6 · Cited by 103

Potential of Thraustochytrids to Partially Replace Fish Oil in Atlantic Salmon Feeds

Carter, C. G., Bransden, M. P., Lewis, T. E., & Nichols, P. D. (2003) · Marine Biotechnology · doi:10.1007/s10126-002-0096-8 · Cited by 100

Distribution of polyunsaturated Fatty acids in bacteria present in intestines of deep-sea fish and shallow-sea poikilothermic animals

Yano, Y., Nakayama, A., & Yoshida, K. (1997) · Applied and Environmental Microbiology · doi:10.1128/aem.63.7.2572-2577.1997 · Cited by 98

Long-chain n — 3 polyunsaturated fatty acid production by members of the marine protistan group the thraustochytrids: screening of isolates and optimisation of docosahexaenoic acid production

Bowles, R. D., Hunt, A. E., Bremer, G. B., Duchars, M. G., & Eaton, R. A. (1999) · Progress in industrial microbiology · doi:10.1016/s0079-6352(99)80112-x · Cited by 97

Dietary factors and lung cancer risk in Japanese: with special reference to fish consumption and adenocarcinomas

Takezaki, T., Hirose, K., Inoue, M., Hamajima, N., Yatabe, Y., Mitsudomi, T., Sugiura, T., Kuroishi, T., & Tajima, K. (2001) · British Journal of Cancer · doi:10.1054/bjoc.2001.1722 · Cited by 95

Mid-chain branched alkanoic acids from “living fossil” demosponges: a link to ancient sedimentary lipids?

Thiel, V., Jenisch, A., Wörheide, G., Löwenberg, A., Joachim Reitner, A., & Michaelis, W. (1999) · Organic Geochemistry · doi:10.1016/s0146-6380(98)00200-9 · Cited by 94

Long-chain n−3 polyunsaturated fatty acid production by members of the marine protistan group the thraustochytrids: screening of isolates and optimisation of docosahexaenoic acid production

Bowles, R. D., Hunt, A. E., Bremer, G. B., Duchars, M. G., & Eaton, R. A. (1999) · Journal of Biotechnology · doi:10.1016/s0168-1656(99)00072-3 · Cited by 94

A bifunctional Δ6‐fatty acyl acetylenase/desaturase from the moss Ceratodon purpureus

Sperling, P., Lee, M. A., Girke, T., Zähringer, U., Stymne, S., & Heinz, E. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01418.x · Cited by 90

Sponge sciences : multidisciplinary perspectives

Watanabe, Y., & 伏谷, 伸. (1998) · Springer eBooks · Cited by 89

A growing family of cytochrome b5-domain fusion proteins

Napier, J. A., Sayanova, O. V., Sperling, P., & Heinz, E. (1999) · Trends in Plant Science · doi:10.1016/s1360-1385(98)01357-0 · Cited by 89

Safety Assessment of DHA-Rich Microalgae from Schizochytrium sp.

Hammond, B. G., Mayhew, D. A., Naylor, M. W., Ruecker, F. A., Mast, R. W., & Sander, W. J. (2001) · Regulatory Toxicology and Pharmacology · doi:10.1006/rtph.2001.1458 · Cited by 89

Isolation and Characterization of a Δ5-Fatty Acid Desaturase fromCaenorhabditis elegans

Watts, J. L., & Browse, J. (1999) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1998.1024 · Cited by 88

Plumbing the depths of PUFA biosynthesis: a novel polyketide synthase-like pathway from marine organisms

Napier, J. A. (2002) · Trends in Plant Science · doi:10.1016/s1360-1385(01)02191-4 · Cited by 88

Functional identification of a fatty acid Δ 5 desaturase gene from Caenorhabditis elegans

Michaelson, L. V., Napier, J. A., Lewis, M. J., Griffiths, G. J., Lazarus, C. M., & Stobart, A. K. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)01385-4 · Cited by 87

Abundance of thraustochytrids in coastal plankton

Naganuma, T., Takasugi, H., & Kimura, H. (1998) · Marine Ecology Progress Series · doi:10.3354/meps162105 · Cited by 86

Production of docosahexaenoic acid byThraustochytrium roseum

Li, Z. Y., & Ward, O. P. (1994) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/bf01569755 · Cited by 85

Catalysts or contributors? Tracking bacterial mediation of early diagenesis in the marine water column

Harvey, H. R., & Macko, S. A. (1997) · Organic Geochemistry · doi:10.1016/s0146-6380(97)00033-8 · Cited by 82

Biomarker techniques to screen for bacteria that produce polyunsaturated fatty acids

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