Isolation of the Candida albicans gene for orotidine-5′-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations

Synergy of the antibiotic colistin with echinocandin antifungals in Candida species

Zeidler, U., Bougnoux, M.-E., Lupan, A., Helynck, O., Doyen, A., Garcia, Z., Sertour, N., Clavaud, C., Munier-Lehmann, H., Saveanu, C., et al. (2013) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dks538 · Cited by 58

β-(1,3)-Glucan Unmasking in Some Candida albicans Mutants Correlates with Increases in Cell Wall Surface Roughness and Decreases in Cell Wall Elasticity

Hasim, S., Allison, D. P., Retterer, S. T., Hopke, A., Wheeler, R. T., Doktycz, M. J., & Reynolds, T. B. (2017) · Infection and Immunity · doi:10.1128/iai.00601-16 · Cited by 58

The Candida albicans Histone Acetyltransferase Hat1 Regulates Stress Resistance and Virulence via Distinct Chromatin Assembly Pathways

Tscherner, M., Zwolanek, F., Jenull, S., Sedlazeck, F. J., Petryshyn, A., Frohner, I. E., Mavrianos, J., Chauhan, N., von Haeseler, A., & Kuchler, K. (2015) · PLOS Pathogens · doi:10.1371/journal.ppat.1005218 · Cited by 57

Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains

Popp, C., Hampe, I. A. I., Hertlein, T., Ohlsen, K., Rogers, P. D., & Morschhäuser, J. (2017) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00584-17 · Cited by 56

cis -Acting Elements within the Candida albicans ERG11 Promoter Mediate the Azole Response through Transcription Factor Upc2p

Oliver, B. G., Song, J. L., Choiniere, J. H., & White, T. C. (2007) · Eukaryotic Cell · doi:10.1128/ec.00331-06 · Cited by 53

Milbemycins: More than Efflux Inhibitors for Fungal Pathogens

Silva, L. V., Sanguinetti, M., Vandeputte, P., Torelli, R., Rochat, B., & Sanglard, D. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02040-12 · Cited by 49

MNN5 Encodes an Iron-Regulated α-1,2-Mannosyltransferase Important for Protein Glycosylation, Cell Wall Integrity, Morphogenesis, and Virulence in Candida albicans

Bai, C., Xu, X.-L., Chan, F.-Y., Lee, R. T. H., & Wang, Y. (2006) · Eukaryotic Cell · doi:10.1128/ec.5.2.238-247.2006 · Cited by 52

Differential Requirement of the Transcription Factor Mcm1 for Activation of the Candida albicans Multidrug Efflux Pump MDR1 by Its Regulators Mrr1 and Cap1

Mogavero, S., Tavanti, A., Senesi, S., Rogers, P. D., & Morschhäuser, J. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01467-10 · Cited by 49

Candida albicans Suppresses Nitric Oxide Generation from Macrophages via a Secreted Molecule

Collette, J. R., Zhou, H., & Lorenz, M. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096203 · Cited by 47

Identification of Off-Patent Drugs That Show Synergism with Amphotericin B or That Present Antifungal Action against Cryptococcus neoformans and Candida spp

Rossi, S. A., de Oliveira, H. C., Agreda-Mellon, D., Lucio, J., Mendes-Giannini, M. J. S., García-Cambero, J. P., & Zaragoza, O. (2020) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01921-19 · Cited by 48

Repurposing FDA approved drugs against the human fungal pathogen, Candida albicans

Kim, K., Zilbermintz, L., & Martchenko, M. (2015) · Annals of Clinical Microbiology and Antimicrobials · doi:10.1186/s12941-015-0090-4 · Cited by 48

Candida albicans Uses Multiple Mechanisms To Acquire the Essential Metabolite Inositol during Infection

Chen, Y.-L., Kauffman, S., & Reynolds, T. B. (2008) · Infection and Immunity · doi:10.1128/iai.01514-07 · Cited by 47

The Glycosylphosphatidylinositol-Anchored Protease Sap9 Modulates the Interaction of Candida albicans with Human Neutrophils

Hornbach, A., Heyken, A., Schild, L., Hube, B., Löffler, J., & Kurzai, O. (2009) · Infection and Immunity · doi:10.1128/iai.00723-09 · Cited by 47

Phenotypic characterization of a Candida albicans strain deficient in its major exoglucanase

del Mar González, M., Díez-Orejas, R., Molero, G., álvarez, A. M., Pla, J., Pla, J., Nombela, C., & Sánchez-PéArez, M. (1997) · Microbiology · doi:10.1099/00221287-143-9-3023 · Cited by 47

Changes in glutathione-dependent redox status and mitochondrial energetic strategies are part of the adaptive response during the filamentation process in Candida albicans

Guedouari, H., Gergondey, R., Bourdais, A., Vanparis, O., Bulteau, A. L., Camadro, J. M., & Auchère, F. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2014.07.006 · Cited by 45

Genetically regulated filamentation contributes to Candida albicans virulence during corneal infection

Jackson, B. E., Wilhelmus, K. R., & Mitchell, B. M. (2007) · Microbial Pathogenesis · doi:10.1016/j.micpath.2006.11.005 · Cited by 45

Proteomic analysis of detergent-resistant membranes from Candida albicans

Insenser, M., Nombela, C., Molero, G., & Gil, C. (2006) · PROTEOMICS · doi:10.1002/pmic.200500465 · Cited by 44

Small Molecule Inhibitors of the Candida albicans Budded-to-Hyphal Transition Act through Multiple Signaling Pathways

Midkiff, J., Borochoff-Porte, N., White, D., & Johnson, D. I. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025395 · Cited by 44

Candida albicans SET1 encodes a histone 3 lysine 4 methyltransferase that contributes to the pathogenesis of invasive candidiasis

Raman, S. B., Nguyen, M. H., Zhang, Z., Cheng, S., Jia, H. Y., Weisner, N., Iczkowski, K., & Clancy, C. J. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05121.x · Cited by 43

Iron restriction-induced adaptations in the wall proteome of Candida albicans

Sorgo, A. G., Brul, S., de Koster, C. G., de Koning, L. J., & Klis, F. M. (2013) · Microbiology · doi:10.1099/mic.0.065599-0 · Cited by 40

Diagnosis of invasive candidiasis by enzyme-linked immunosorbent assay using the N-terminal fragment of Candida albicans hyphal wall protein 1

Laín, A., Elguezabal, N., Brena, S., García-Ruiz, J. C., del Palacio, A., Moragues, M. D., & Pontón, J. (2007) · BMC Microbiology · doi:10.1186/1471-2180-7-35 · Cited by 40

The protein kinase Ire1 impacts pathogenicity of Candida albicans by regulating homeostatic adaptation to endoplasmic reticulum stress

Sircaik, S., Román, E., Bapat, P., Lee, K. K., Andes, D. R., Gow, N. A. R., Nobile, C. J., Pla, J., & Panwar, S. L. (2021) · Cellular Microbiology · doi:10.1111/cmi.13307 · Cited by 41

The RTA3 Gene, Encoding a Putative Lipid Translocase, Influences the Susceptibility of Candida albicans to Fluconazole

Whaley, S. G., Tsao, S., Weber, S., Zhang, Q., Barker, K. S., Raymond, M., & Rogers, P. D. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00732-16 · Cited by 41

Functional Dissection of a Candida albicans Zinc Cluster Transcription Factor, the Multidrug Resistance Regulator Mrr1

Schubert, S., Popp, C., Rogers, P. D., & Morschhäuser, J. (2011) · Eukaryotic Cell · doi:10.1128/ec.05100-11 · Cited by 39

Effects of Human and Porcine Adipose Extracellular Matrices Decellularized by Enzymatic or Chemical Methods on Macrophage Polarization and Immunocompetence

Cicuéndez, M., Casarrubios, L., Feito, M. J., Madarieta, I., Garcia-Urkia, N., Murua, O., Olalde, B., Briz, N., Diez-Orejas, R., & Portolés, M. T. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22083847 · Cited by 39

Involvement of the mitogen activated protein kinase Hog1p in the response of Candida albicansto iron availability

Kaba, H. E., Nimtz, M., Müller, P. P., & Bilitewski, U. (2013) · BMC Microbiology · doi:10.1186/1471-2180-13-16 · Cited by 37

Rapid redistribution of phosphatidylinositol-(4,5)-bisphosphate and septins during the Candida albicans response to caspofungin

Badrane, H., Nguyen, M. H., Blankenship, J. R., Cheng, S., Hao, B., Mitchell, A. P., & Clancy, C. J. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00112-12 · Cited by 38

Unanticipated Heterogeneity in Growth Rate and Virulence among Candida albicans AAF1 Null Mutants

Rieg, G., Fu, Y., Ibrahim, A. S., Zhou, X., Filler, S. G., & Edwards, J. E. (1999) · Infection and Immunity · doi:10.1128/iai.67.7.3193-3198.1999 · Cited by 36

ERG2 and ERG24 Are Required for Normal Vacuolar Physiology as Well as Candida albicans Pathogenicity in a Murine Model of Disseminated but Not Vaginal Candidiasis

Luna-Tapia, A., Peters, B. M., Eberle, K. E., Kerns, M. E., Foster, T. P., Marrero, L., Noverr, M. C., Fidel, P. L., & Palmer, G. E. (2015) · Eukaryotic Cell · doi:10.1128/ec.00116-15 · Cited by 35

Fluconazole at subinhibitory concentrations induces the oxidative- and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida albicans to phagocytes

Arana, D. M., Nombela, C., & Pla, J. (2010) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkp407 · Cited by 35

Candida albicans Biofilms Are Generally Devoid of Persister Cells

Denega, I., d’Enfert, C., & Bachellier-Bassi, S. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01979-18 · Cited by 32

Candida albicans amphotericin B-tolerant persister formation is closely related to surface adhesion

Sun, J., Li, Z., Chu, H., Guo, J., Jiang, G., & Qi, Q. (2016) · Mycopathologia · doi:10.1007/s11046-015-9894-1 · Cited by 32

Candida albicans strains deficient in CHS7, a key regulator of chitin synthase III, exhibit morphogenetic alterations and attenuated virulence

Sanz, M., Carrano, L., Jiménez, C., Candiani, G., Trilla, J. A., Durán, A., & Roncero, C. (2005) · Microbiology · doi:10.1099/mic.0.28093-0 · Cited by 32

Structural and functional analysis of EntV reveals a 12 amino acid fragment protective against fungal infections

Cruz, M. R., Cristy, S., Guha, S., De Cesare, G. B., Evdokimova, E., Sanchez, H., Borek, D., Miramón, P., Yano, J., Fidel, P. L., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33613-1 · Cited by 30

Oral epithelium–Candida glabrata interactions in vitro

Li, L., & Dongari‐Bagtzoglou, A. (2007) · Oral Microbiology and Immunology · doi:10.1111/j.1399-302x.2007.00342.x · Cited by 29

Native human and mouse skin infection models to study Candida auris-host interactions

Seiser, S., Arzani, H., Ayub, T., Phan-Canh, T., Staud, C., Worda, C., Kuchler, K., & Elbe-Bürger, A. (2024) · Microbes and Infection · doi:10.1016/j.micinf.2023.105234 · Cited by 29

Candida auris —macrophage cellular interactions and transcriptional response

Miramón, P., Pountain, A. W., & Lorenz, M. C. (2023) · Infection and Immunity · doi:10.1128/iai.00274-23 · Cited by 29

Trafficking through the Late Endosome Significantly Impacts Candida albicans Tolerance of the Azole Antifungals

Luna-Tapia, A., Kerns, M. E., Eberle, K. E., Jursic, B. S., & Palmer, G. E. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.04239-14 · Cited by 28

The Candida albicans HIR histone chaperone regulates the yeast-to-hyphae transition by controlling the sensitivity to morphogenesis signals

Jenull, S., Tscherner, M., Gulati, M., Nobile, C. J., Chauhan, N., & Kuchler, K. (2017) · Scientific Reports · doi:10.1038/s41598-017-08239-9 · Cited by 28

PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes

Eckert, S. E., Heinz, W. J., Zakikhany, K., Thewes, S., Haynes, K., Hube, B., & Mühlschlegel, F. A. (2007) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2006.12.006 · Cited by 29

Human oral keratinocyte E-cadherin degradation by Candida albicans and Candida glabrata

Pärnänen, P., Meurman, J. H., Samaranayake, L., & Virtanen, I. (2010) · Journal of Oral Pathology & Medicine · doi:10.1111/j.1600-0714.2009.00866.x · Cited by 28

Sap6, a secreted aspartyl proteinase, participates in maintenance the cell surface integrity of Candida albicans

Buu, L.-M., & Chen, Y.-C. (2013) · Journal of Biomedical Science · doi:10.1186/1423-0127-20-101 · Cited by 27

The regulatory proteins Rtg1/3 govern sphingolipid homeostasis in the human-associated yeast Candida albicans

Moreno-Velásquez, S. D., Tint, S. H., del Olmo Toledo, V., Torsin, S., De, S., & Pérez, J. C. (2020) · Cell Reports · doi:10.1016/j.celrep.2019.12.022 · Cited by 25

SAGA/ADA Complex Subunit Ada2 Is Required for Cap1- but Not Mrr1-Mediated Upregulation of the Candida albicans Multidrug Efflux Pump MDR1

Ramírez-Zavala, B., Mogavero, S., Schöller, E., Sasse, C., Rogers, P. D., & Morschhäuser, J. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.03065-14 · Cited by 25

The UPC2 Promoter in Candida albicans Contains Two cis -Acting Elements That Bind Directly to Upc2p, Resulting in Transcriptional Autoregulation

Hoot, S. J., Brown, R. P., Oliver, B. G., & White, T. C. (2010) · Eukaryotic Cell · doi:10.1128/ec.00130-10 · Cited by 25

Mitochondrial Complex V α Subunit Is Critical for Candida albicans Pathogenicity through Modulating Multiple Virulence Properties

Li, S.-X., Song, Y.-J., Zhang, Y.-S., Wu, H.-T., Guo, H., Zhu, K.-J., Li, D.-M., & Zhang, H. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00285 · Cited by 25

Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis

Awasthi, D., Chopra, S., Cho, B. A., Emmanuelli, A., Sandoval, T. A., Hwang, S.-M., Chae, C.-S., Salvagno, C., Tan, C., Vasquez-Urbina, L., et al. (2023) · Journal of Clinical Investigation · doi:10.1172/jci167359 · Cited by 24

A natural histone H2A variant lacking the Bub1 phosphorylation site and regulated depletion of centromeric histone CENP-A foster evolvability in Candida albicans

Brimacombe, C. A., Burke, J. E., Parsa, J.-Y., Catania, S., O’Meara, T. R., Witchley, J. N., Burrack, L. S., Madhani, H. D., & Noble, S. M. (2019) · PLoS Biology · doi:10.1371/journal.pbio.3000331 · Cited by 22

ALS51, a newly discovered gene in the Candida albicans ALS family, created by intergenic recombination: analysis of the gene and protein, and implications for evolution of microbial gene families

Zhao, X., Oh, S.-H., Coleman, D. A., & Hoyer, L. L. (2011) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2010.00769.x · Cited by 22

Loss of Heterozygosity at an Unlinked Genomic Locus Is Responsible for the Phenotype of a Candida albicans sap4 Δ sap5 Δ sap6 Δ Mutant

Dunkel, N., & Morschhäuser, J. (2011) · Eukaryotic Cell · doi:10.1128/ec.00281-10 · Cited by 20

Kch1 Family Proteins Mediate Essential Responses to Endoplasmic Reticulum Stresses in the Yeasts Saccharomyces cerevisiae and Candida albicans

Stefan, C. P., & Cunningham, K. W. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.508705 · Cited by 15

Constitutive ALS3 expression in Candida albicans enhances adhesion and biofilm formation of efg1, but not cph1 mutant strains

Schena, N. C., Baker, K. M., Stark, A. A., Thomas, D. P., & Cleary, I. A. (2023) · PLOS ONE · doi:10.1371/journal.pone.0286547 · Cited by 15

The F 1 F o -ATP synthase α subunit of Candida albicans induces inflammatory responses by controlling amino acid catabolism

Li, S., Liu, Y., Weng, L., Zhao, Y., Zhang, Y., Zhang, Z., Yang, Y., Chen, Q., Liu, X., & Zhang, H. (2023) · Virulence · doi:10.1080/21505594.2023.2190645 · Cited by 3