Reduced fatigue in electrically stimulated muscle using dual channel intrafascicular electrodes with interleaved stimulation
Abstract
Pairs of intrafascicular electrodes were implanted within single fascicles of the nerve innervating the gastrocnemius muscle in cats. Measurements were made of fatigue induced in the muscle by single and dual channel tetanic stimulation. The level and rate of fatigue induced by concurrent dual channel stimulation (pulses presented simultaneously to the two electrodes) did not differ significantly from that induced by single channel stimulation. However, a significant reduction in the level and rate of muscle fatigue was found with interleaved dual channel stimulation. The extent of reduction in fatigue was found to be inversely related to the amount of overlap in the axonal populations activated by each of the two electrodes.
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Stimulation overlap must be inferred from indirect measurements.
“Stimulation overlap must, therefore, be inferred from indirect measurements [9].”
From Optimization of selective stimulation parameters for multi-contact electrodes (2013) · cites this paper as [9]
Cites
Physiological types and histochemical profiles in motor units of the cat gastrocnemius
Burke, R. E., Levine, D. N., Tsairis, P., & Zajac, F. E. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010369 · Cited by 1,549 · see citing works
Functional Electrical Stimulation: Standing and Walking after Spinal Cord Injury
Kralj, A. R., & Bajd, T. (2021) · Routledge eBooks · doi:10.1201/9780203755402 · Cited by 413 · see citing works
Motor units in cat soleus muscle: physiological, histochemical and morphological characteristics
Burke, R. E., Levine, D. N., Salcman, M., & Tsairis, P. (1974) · The Journal of Physiology · doi:10.1113/jphysiol.1974.sp010540 · Cited by 324 · see citing works
PROPERTIES OF MOTOR UNITS IN A HOMOGENEOUS RED MUSCLE (SOLEUS) OF THE CAT
McPhedran, A. M., Wuerker, R. B., & Henneman, E. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.1.71 · Cited by 323 · see citing works
PROPERTIES OF MOTOR UNITS IN A HETEROGENEOUS PALE MUSCLE (M. GASTROCNEMIUS) OF THE CAT
Wuerker, R. B., McPhedran, A. M., & Henneman, E. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.1.85 · Cited by 318 · see citing works
Functional Electrical Stimulation: Standing and Walking After Spinal Cord Injury
Condie, E., & Condie, D. (1990) · Physiotherapy · doi:10.1016/s0031-9406(10)62194-3 · Cited by 318 · see citing works
Halbertsma, J. M. (1983) · PubMed · Cited by 310 · see citing works
Zajac, F. E., & Faden, J. S. (1985) · Journal of Neurophysiology · doi:10.1152/jn.1985.53.5.1303 · Cited by 236 · see citing works
Selective stimulation of peripheral nerve fibers using dual intrafascicular electrodes
Yoshida, K., & Horch, K. (1993) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.243412 · Cited by 208 · see citing works
Self-citationA nerve cuff technique for selective excitation of peripheral nerve trunk regions
Sweeney, J. D., Ksienski, D. A., & Mortimer, J. T. (1990) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.55681 · Cited by 196 · see citing works
Chronically implanted intrafascicular recording electrodes
Lefurge, T., Goodall, E., Horch, K., Stensaas, L., & Schoenberg, A. (1991) · Annals of Biomedical Engineering · doi:10.1007/bf02368469 · Cited by 172 · see citing works
Self-citationKralj, A. R., Bajd, T., Turk, R., Krajnik, J., & Benko, H. (1983) · PubMed · Cited by 159 · see citing works
Sensitivity and selectivity of intraneural stimulation using a silicon electrode array
Rutten, W. L. C., van Wier, H. J., & Put, J. H. M. (1991) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.76386 · Cited by 129 · see citing works
A method to effect physiological recruitment order in electrically activated muscle
Fang, Z.-P., & Mortimer, J. T. (1991) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.76384 · Cited by 125 · see citing works
Orderly stimulation of skeletal muscle motor units with tripolar nerve cuff electrode
Baratta, R. V., ICHIE, M., Hwang, S. K., & Solomonow, M. (1989) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.30809 · Cited by 118 · see citing works
Muscle recruitment with intrafascicular electrodes
Nannini, N., & Horch, K. (1991) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.83589 · Cited by 94 · see citing works
Self-citationSimulation of intrafascicular and extraneural nerve stimulation
Veltink, P. H., van Alste, J. A., & Boom, H. B. K. (1988) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.1338 · Cited by 71 · see citing works
Sequential motor unit stimulation through peripheral motor nerves in the cat
Petrofsky, J. S. (1979) · Medical & Biological Engineering & Computing · doi:10.1007/bf02440958 · Cited by 67 · see citing works
Posture switching for prolonging functional electrical stimulation standing in paraplegic patients
Krajl, A., Bajd, T., Turk, R., et al. (1986) · Spinal Cord · doi:10.1038/sc.1986.31 · Cited by 66 · see citing works
Information contained in sensory nerve recordings made with intrafascicular electrodes
Goodall, E. V., Lefurge, T. M., & Horch, K. W. (1991) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.83604 · Cited by 63 · see citing works
Self-citationMultielectrode intrafascicular and extraneural stimulation
Veltink, P. H., van Alsté, J. A., & Boom, H. B. K. (1989) · Medical and Biological Engineering and Computing · doi:10.1007/bf02442165 · Cited by 62 · see citing works
Properties of types of motor units in the medial gastrocnemius muscle of the cat
Proske, U., & Waite, P. M. E. (1974) · Brain Research · doi:10.1016/0006-8993(74)90300-x · Cited by 53 · see citing works
Simulation of multipolar fiber selective neural stimulation using intrafascicular electrodes
Meier, J. H., Rotten, W. L. C., Zoutman, A. E., Boom, H. B. K., & Bergveld, P. (1992) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.121643 · Cited by 52 · see citing works
Technology and Long-term Application of an Epineural Electrode
THOMA, H., CIRSCH, W., HOLLE, J., & Mayr, W. (1989) · ASAIO Transactions · doi:10.1097/00002480-198907000-00103 · Cited by 43 · see citing works
Powers, R. K., & Binder, M. D. (1991) · Journal of Neurophysiology · doi:10.1152/jn.1991.66.3.905 · Cited by 42 · see citing works
Sur le rôle de la méthylation du DNA dans le contrôle par I’hôte de la modification du bactériophage
Arber, W. (2008) · Pathologia et Microbiologia · doi:10.1159/000161613 · Cited by 39 · see citing works
Influences of stimulation conditions on recruitment of myelinated nerve fibres: a model study
Veltink, P. H., van Alste, J. A., & Boom, H. B. K. (1988) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.8671 · Cited by 37 · see citing works
Electrical Activation of Skeletal Muscle by Sequential Stimulation
Peckham, P. H., Meulen, J. P. V. D., & RESWICK, J. B. (1970) · Springer eBooks · doi:10.1007/978-1-4684-1836-1_8 · Cited by 32 · see citing works
Multi-channel indirect stimulation reduces muscle fatigue
Happak, W., Gruber, H., HOLLE, J., et al. (2003) · doi:10.1109/iembs.1989.95701 · Cited by 14 · see citing works
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Branner, A., Stein, R. B., Fernandez, E., Aoyagi, Y., & Normann, R. A. (2004) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2003.820321 · Cited by 301 · see citing works
Selective Electrical Interfaces with the Nervous System
Rutten, W. L. C. (2002) · Annual Review of Biomedical Engineering · doi:10.1146/annurev.bioeng.4.020702.153427 · Cited by 276 · see citing works
Sputtered Iridium Oxide Films as Charge Injection Material for Functional Electrostimulation
Slavcheva, E., Vitushinsky, R., Mokwa, W., & Schnakenberg, U. (2004) · Journal of The Electrochemical Society · doi:10.1149/1.1747881 · Cited by 154 · see citing works
A slowly penetrating interfascicular nerve electrode for selective activation of peripheral nerves
Tyler, D. J., & Durand, D. M. (1997) · IEEE Transactions on Rehabilitation Engineering · doi:10.1109/86.559349 · Cited by 108 · see citing works
McDonnall, D., Clark, G. A., & Normann, R. A. (2004) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2004.828425 · Cited by 98 · see citing works
Subfascicle stimulation selectivity with the flat interface nerve electrode
Leventhal, D. K., & Durand, D. M. (2003) · Annals of Biomedical Engineering · doi:10.1114/1.1569266 · Cited by 81 · see citing works
Recruitment characteristics of nerve fascicles stimulated by a multigroove electrode
Koole, P., Holsheimer, J., Struijk, J. J., & Verloop, A. J. (1997) · IEEE Transactions on Rehabilitation Engineering · doi:10.1109/86.559348 · Cited by 56 · see citing works
Selective motor unit recruitment via intrafascicular multielectrode stimulation
McDonnall, D., Clark, G. A., & Normann, R. A. (2004) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y04-047 · Cited by 53 · see citing works
Gaunt, R. A., Hokanson, J. A., & Weber, D. J. (2009) · Journal of Neural Engineering · doi:10.1088/1741-2560/6/5/055009 · Cited by 53 · see citing works
Intrafascicular electrodes for stimulation and recording from mudpuppy spinal roots
Yoshida, K., Jovanović, K., & Stein, R. B. (2000) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(99)00176-4 · Cited by 49 · see citing works
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Fisher, L. E., Tyler, D. J., & Triolo, R. J. (2013) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/1743-0003-10-25 · Cited by 45 · see citing works
Normann, R. A., Dowden, B. R., Frankel, M. A., Wilder, A. M., Hiatt, S. D., Ledbetter, N. M., Warren, D. A., & Clark, G. A. (2012) · Journal of Neural Engineering · doi:10.1088/1741-2560/9/2/026019 · Cited by 37 · see citing works
Influence of synchronous and sequential stimulation on muscle fatigue
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- Authors
- Yoshida, K., & Horch, K.
- Affiliations
- University of Utah (US)
- ORCID
- Yoshida, Ken
- Venue
- Annals of Biomedical Engineering
- Published
- 1993-11
- Volume
- 21
- Issue
- 6
- Pages
- 709-714
- ISSN
- 0090-6964 (ISSN-L)
- 1573-9686
- OpenAlex
- W2015912019
- Cited by
- 69
- References
- 29
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2020: 2 · 2018: 2 · 2017: 4 · 2016: 3 · 2015: 2 · 2014: 5 · 2013: 3 · 2012: 3
- FWCI
- 0.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Annals of Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Biomedical Engineering › Muscle activation and electromyography studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Keywords
- muscle fatigue, electrically stimulated muscle, intrafascicular electrodes, tetanic stimulation, gastrocnemius, peripheral nerve stimulation, cats
- MeSH terms
- Animals, Cats, Electric Stimulation, Electrodes, Implanted, Motor Neurons, Muscles, Reference Values
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