Cited by 470

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids

Open access

Koopman, René, Schaart, Gert, Hesselink, Matthijs K.·2001·Histochemistry and Cell Biology

DOI 10.1007/s004180100297

Open this paper in CoChat — free account

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1007/s004180100297

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1 H NMR spectroscopy study
Krssak, M., Falk Petersen, K., Dresner, A., DiPietro, L., Vogel, S. M., Rothman, D. L., Shulman, G. I., & Roden, M. (1999) · Diabetologia · doi:10.1007/s001250051123 · Cited by 1,264
Skeletal muscle triglyceride levels are inversely related to insulin action
Pan, D. A., Lillioja, S., Kriketos, A. D., Milner, M. R., Baur, L. A., Bogardus, C., Jenkins, A. B., & Storlien, L. H. (1997) · Diabetes · doi:10.2337/diabetes.46.6.983 · Cited by 1,179
Skeletal Muscle Triglyceride Levels Are Inversely Related to Insulin Action
Pan, D. A., Lillioja, S., Kriketos, A. D., Milner, M. R., Baur, L. A., Bogardus, C., Jenkins, A. B., & Storlien, L. H. (1997) · Diabetes · doi:10.2337/diab.46.6.983 · Cited by 1,179
Spectrofluorometric studies of the lipid probe, nile red.
Greenspan, P., & Fowler, S. D. (1985) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)34307-8 · Cited by 980
Intramuscular lipid content is increased in obesity and decreased by weight loss
Goodpaster, B. H., Theriault, R., Watkins, S. C., & Kelley, D. E. (2000) · Metabolism · doi:10.1016/s0026-0495(00)80010-4 · Cited by 526 · cited 18×
“As we apparently lost the majority of the stained lipids in the differentiation and rinsing steps performed after the oil red O stain, we successively performed the procedure described by Goodpaster et al. (2000b), where the differentiation procedure is skipped.”
BackgroundMethodInfluential

Show all 5 references

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans
Timmers, S., Konings, E., Bilet, L., Houtkooper, R. H., van de Weijer, T., Goossens, G. H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.10.002 · Cited by 1,320
Self-citation
Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes
Cox, P. J., Kirk, T., Ashmore, T., Willerton, K., Evans, R., Smith, A., Murray, A. J., Stubbs, B., West, J., McLure, S. W., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.07.010 · Cited by 530
One Week of Bed Rest Leads to Substantial Muscle Atrophy and Induces Whole-Body Insulin Resistance in the Absence of Skeletal Muscle Lipid Accumulation
Dirks, M. L., Wall, B. T., van de Valk, B., Holloway, T. M., Holloway, G. P., Chabowski, A., Goossens, G. H., & van Loon, L. J. C. (2016) · Diabetes · doi:10.2337/db15-1661 · Cited by 391
Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity
Meex, R. C. R., Schrauwen-Hinderling, V. B., Moonen-Kornips, E., Schaart, G., Mensink, M., Phielix, E., van de Weijer, T., Sels, J.-P., Schrauwen, P., & Hesselink, M. K. C. (2010) · Diabetes · doi:10.2337/db09-1322 · Cited by 355
Self-citation
Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes
van Loon, L. J. C., Koopman, R., Manders, R., van der Weegen, W., van Kranenburg, G. P., & Keizer, H. A. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00464.2003 · Cited by 239
Self-citation
Adipogenic and lipolytic effects of chronic glucocorticoid exposure
Campbell, J. E., Peckett, A. J., D'souza, A. M., Hawke, T. J., & Riddell, M. C. (2011) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00045.2010 · Cited by 228
Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5
Shepherd, S. O., Cocks, M., Tipton, K. D., Ranasinghe, A. M., Barker, T. A., Burniston, J. G., Wagenmakers, A. J. M., & Shaw, C. S. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2012.240952 · Cited by 207
Use of intramuscular triacylglycerol as a substrate source during exercise in humans
van Loon, L. J. C. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00368.2004 · Cited by 205
Intramyocellular Lipid Content in Human Skeletal Muscle
Schrauwen‐Hinderling, V. B., Hesselink, M. K. C., Schrauwen, P., & Kooi, M. E. (2006) · Obesity · doi:10.1038/oby.2006.47 · Cited by 202
Self-citation
Dendritic cells in multiple sclerosis lesions: maturation stage, myelin uptake, and interaction with proliferating T cells
Serafini, B., Rosicarelli, B., Magliozzi, R., Stigliano, E., Capello, E., Mancardi, G. L., & Aloisi, F. (2006) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/65.2.124 · Cited by 176
Thyroid hormone regulates distinct paths to maturation in pigment cell lineages
Saunders, L. M., Mishra, A. K., Aman, A. J., Lewis, V. M., Toomey, M. B., Packer, J. S., Qiu, X., McFaline-Figueroa, J. L., Corbo, J. C., Trapnell, C., et al. (2019) · eLife · doi:10.7554/elife.45181 · Cited by 170
Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus
Mensink, M., Hesselink, M. K. C., Russell, A. P., Schaart, G., Sels, J.-P., & Schrauwen, P. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803567 · Cited by 160
Self-citation
Prolonged fasting identifies skeletal muscle mitochondrial dysfunction as consequence rather than cause of human insulin resistance
Hoeks, J., van Herpen, N. A., Mensink, M., Moonen-Kornips, E., van Beurden, D., Hesselink, M. K. C., & Schrauwen, P. (2010) · Diabetes · doi:10.2337/db10-0519 · Cited by 156
Self-citation
Exercise in the fasted state facilitates fibre type‐specific intramyocellular lipid breakdown and stimulates glycogen resynthesis in humans
De Bock, K., Richter, E. A., Russell, A. P., Eijnde, B. O., Derave, W., Ramaekers, M., Koninckx, E., Léger, B., Verhaeghe, J., & Hespel, P. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.083170 · Cited by 145
Evidence for a Direct Effect of the NAD+ Precursor Acipimox on Muscle Mitochondrial Function in Humans
van de Weijer, T., Phielix, E., Bilet, L., Williams, E. G., Ropelle, E. R., Bierwagen, A., Livingstone, R., Nowotny, P., Sparks, L. M., Paglialunga, S., et al. (2015) · Diabetes · doi:10.2337/db14-0667 · Cited by 139
Self-citation
Muscle-Specific Adaptations, Impaired Oxidative Capacity and Maintenance of Contractile Function Characterize Diet-Induced Obese Mouse Skeletal Muscle
Shortreed, K. E., Krause, M. P., Huang, J. H., Dhanani, D., Moradi, J., Ceddia, R. B., & Hawke, T. J. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007293 · Cited by 131
Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling
Kienesberger, P. C., Lee, D., Pulinilkunnil, T., Brenner, D. S., Cai, L., Magnes, C., Koefeler, H. C., Streith, I. E., Rechberger, G. N., Haemmerle, G., et al. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.047787 · Cited by 120
Saturated Very Long Chain Fatty Acids Are Required for the Production of Infectious Human Cytomegalovirus Progeny
Koyuncu, E., Purdy, J. G., Rabinowitz, J. D., & Shenk, T. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003333 · Cited by 114
Carbohydrate supplementation during prolonged cycling exercise spares muscle glycogen but does not affect intramyocellular lipid use
Stellingwerff, T., Boon, H., Gijsen, A. P., Stegen, J. H. C. H., Kuipers, H., & van Loon, L. J. C. (2007) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-007-0236-0 · Cited by 110
High Oxidative Capacity Due to Chronic Exercise Training Attenuates Lipid-Induced Insulin Resistance
Phielix, E., Meex, R., Ouwens, D. M., Sparks, L., Hoeks, J., Schaart, G., Moonen-Kornips, E., Hesselink, M. K. C., & Schrauwen, P. (2012) · Diabetes · doi:10.2337/db11-1832 · Cited by 99
“Fresh cryosections of 5 mm were stained for IMTGs by Oil Red O staining combined with fibertyping and immunolabeling of the basal membrane marker laminin to allow quantification, as described previously (31).”
MethodSelf-citation
Celastrol-loaded PEG- b -PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis
Allen, S. D., Liu, Y.-G., Kim, T., Bobbala, S., Yi, S., Zhang, X., Choi, J., & Scott, E. A. (2019) · Biomaterials Science · doi:10.1039/c8bm01224e · Cited by 95
Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle
Eshima, H., Tamura, Y., Kakehi, S., Kurebayashi, N., Murayama, T., Nakamura, K., Kakigi, R., Okada, T., Sakurai, T., Kawamori, R., et al. (2017) · Physiological Reports · doi:10.14814/phy2.13250 · Cited by 88
Relationships between Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes Mellitus
van de Weijer, T., Sparks, L. M., Phielix, E., Meex, R. C., van Herpen, N. A., Hesselink, M. K. C., Schrauwen, P., & Schrauwen-Hinderling, V. B. (2013) · PLoS ONE · doi:10.1371/journal.pone.0051648 · Cited by 87
“In these biopsies, muscle lipid accumulation was assessed histochemically in muscle cross-sections using a modified oil red O staining for fluorescence microscopy [23].”
MethodSelf-citation
Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity
Timmers, S., Nabben, M., Bosma, M., van Bree, B., Lenaers, E., van Beurden, D., Schaart, G., Westerterp-Plantenga, M. S., Langhans, W., Hesselink, M. K. C., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1206868109 · Cited by 80
Self-citation
Resveratrol supplementation does not augment performance adaptations or fibre-type-specific responses to high-intensity interval training in humans
Scribbans, T. D., Ma, J. K., Edgett, B. A., Vorobej, K. A., Mitchell, A. S., Zelt, J. G. E., Simpson, C. A., Quadrilatero, J., & Gurd, B. J. (2014) · Applied Physiology Nutrition and Metabolism · doi:10.1139/apnm-2014-0070 · Cited by 79
A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys
Pugh, T. D., Conklin, M. W., Evans, T. D., Polewski, M. A., Barbian, H. J., Pass, R., Anderson, B. D., Colman, R. J., Eliceiri, K. W., Keely, P. J., et al. (2013) · Aging Cell · doi:10.1111/acel.12091 · Cited by 81
Resveratrol improves ex vivo mitochondrial function but does not affect insulin sensitivity or brown adipose tissue in first degree relatives of patients with type 2 diabetes
de Ligt, M., Bruls, Y. M. H., Hansen, J., Habets, M.-F., Havekes, B., Nascimento, E. B. M., Moonen-Kornips, E., Schaart, G., Schrauwen-Hinderling, V. B., van Marken Lichtenbelt, W., et al. (2018) · Molecular Metabolism · doi:10.1016/j.molmet.2018.04.004 · Cited by 79
Self-citation
A rodent model of rapid-onset diabetes (ROD) induced by glucocorticoids and high-fat feeding
Shpilberg, Y., Beaudry, J. L., D'Souza, A., Campbell, J. E., Peckett, A., & Riddell, M. C. (2011) · Disease Models & Mechanisms · doi:10.1242/dmm.008912 · Cited by 77
Influence of prolonged endurance cycling and recovery diet on intramuscular triglyceride content in trained males
van Loon, L. J. C., Schrauwen-Hinderling, V. B., Koopman, R., Wagenmakers, A. J. M., Hesselink, M. K. C., Schaart, G., Kooi, M. E., & Saris, W. H. M. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00112.2003 · Cited by 74
Self-citation
3,5‐Diiodo‐L‐thyronine prevents high‐fat‐diet‐induced insulin resistance in rat skeletal muscle through metabolic and structural adaptations
Moreno, M., Silvestri, E., De Matteis, R., de Lange, P., Lombardi, A., Glinni, D., Senese, R., Cioffi, F., Salzano, A. M., Scaloni, A., et al. (2011) · The FASEB Journal · doi:10.1096/fj.11-181982 · Cited by 71
Mitochondrial function, content and ROS production in rat skeletal muscle: effect of high-fat feeding
Hoeks, J., Briedé, J. J., de Vogel, J., Schaart, G., Nabben, M., Moonen-Kornips, E., Hesselink, M. K. C., & Schrauwen, P. (2008) · FEBS Letters · doi:10.1016/j.febslet.2008.01.013 · Cited by 63
Self-citation
Intramyocellular lipid droplets and insulin sensitivity, the human perspective
Gemmink, A., Goodpaster, B. H., Schrauwen, P., & Hesselink, M. K. C. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2017.07.010 · Cited by 62
Self-citation
Exercise-induced attenuation of obesity, hyperinsulinemia, and skeletal muscle lipid peroxidation in the OLETF rat
Morris, R. T., Laye, M. J., Lees, S. J., Rector, R. S., Thyfault, J. P., & Booth, F. W. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01034.2007 · Cited by 56
Diphenyl diselenide modulates oxLDL-induced cytotoxicity in macrophage by improving the redox signaling
Straliotto, M. R., Hort, M. A., Fiuza, B., Rocha, J. B. T., Farina, M., Chiabrando, G., & de Bem, A. F. (2013) · Biochimie · doi:10.1016/j.biochi.2013.04.008 · Cited by 36
Assessment of intramuscular triglycerides: contribution to metabolic abnormalities
Dubé, J., & Goodpaster, B. H. (2006) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/01.mco.0000241664.38385.12 · Cited by 31
Evaluation of Lipid Accumulation Using Electrical Impedance Measurement under Three-Dimensional Culture Condition
Zemmyo, D., & Miyata, S. (2019) · Micromachines · doi:10.3390/mi10070455 · Cited by 7

Authors: Koopman, R., Schaart, G., & Hesselink, M. K.
Venue: Histochemistry and Cell Biology
Publisher: Springer Science and Business Media LLC
Published: 2001-07
Volume: 116
Issue: 1
Pages: 63-68
ISSN: 0948-6143 (ISSN-L)
1432-119X
DOI: 10.1007/s004180100297
OpenAlex: W1555460575
Cited by: 470
References: 5
FWCI: 3.00
Type: journal article
Language: en
Open access: green

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.

Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids

Overview

Integrity signals

Verification

Claims the paper makes

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks

Data sources