Cited by 437Sports Performance and TrainingCardiovascular and exercise physiologyMuscle Physiology and Disorders

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New fundamental resistance exercise determinants of molecular and cellular muscle adaptations

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Toigo, Marco, Boutellier, Urs·2006·European Journal of Applied Physiology

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Abstract

Abstract Physical activity relies on muscular force. In adult skeletal muscle, force results from the contraction of postmitotic, multinucleated myofibres of different contractile and metabolic properties. Myofibres can adapt to (patho-)physiological conditions of altered functional demand by radial growth, longitudinal growth, and regulation of fibre type functional gene modules. The adaptation's specificity depends on the distinct molecular and cellular events triggered by unique combinations of conditional cues. In order to derive effective and tailored exercise prescriptions, it must be determined (1) which mechano-biological condition leads to what molecular/cellular response, and (2) how this molecular/cellular response relates to the structural, contractile, and metabolic adaptation. It follows that a thorough mechano-biological description of the loading condition is imperative. Unfortunately, the definition of (resistance) exercise conditions in the past and present literature is insufficient. It is classically limited to load magnitude, number of repetitions and sets, rest in-between sets, number of interventions/week, and training period. In this review, we show why the current description is insufficient, and identify new determinants of quantitative and/or qualitative effects on skeletal muscle with respect to resistance exercise in healthy, adult humans. These new mandatory determinants comprise the fractional and temporal distribution of the contraction modes per repetition, duration of one repetition, rest in-between repetitions, time under tension, muscular failure, range of motion, recovery time, and anatomical definition. We strongly recommend to standardise the design and description of all future resistance exercise investigations by using the herein proposed set of 13 mechano-biological determinants (classical and new ones).

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Calcium's Role in Mechanotransduction during Muscle Development
Damm, T. B., & Egli, M. (2014) · Cellular Physiology and Biochemistry · doi:10.1159/000356667 · Cited by 14,552
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
Vivanco, I., & Sawyers, C. L. (2002) · Nature reviews. Cancer · doi:10.1038/nrc839 · Cited by 6,155
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
Glickman, M. H., & Ciechanover, A. J. (2002) · Physiological Reviews · doi:10.1152/physrev.00027.2001 · Cited by 4,296
Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member
McPherron, A. C., Lawler, A. M., & Lee, S.-J. (1997) · Nature · doi:10.1038/387083a0 · Cited by 4,013
SATELLITE CELL OF SKELETAL MUSCLE FIBERS
Mauro, A. (1961) · The Journal of Cell Biology · doi:10.1083/jcb.9.2.493 · Cited by 3,683
Identification of ubiquitin ligases required for skeletal muscle atrophy.
Bodine, S. C., Latres, E., Baumhueter, S., Lai, V. K.-M., Nunez, L., Clarke, B. A., Poueymirou, W. T., Panaro, F. J., Na, E., Dharmarajan, K., et al. (2001) · Science · doi:10.1126/science.1065874 · Cited by 3,521
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy.
Sandri, M., Sandri, C., Gilbert, A., Skurk, C., Calabria, E., Picard, A., Walsh, K., Schiaffino, S., Lecker, S. H., & Goldberg, A. L. (2004) · Cell · doi:10.1016/s0092-8674(04)00400-3 · Cited by 3,012
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
Bodine, S. C., Stitt, T. N., Gonzalez, M., Kline, W. O., Stover, G. L., Bauerlein, R., Zlotchenko, E., Scrimgeour, A., Lawrence, J. C., Glass, D. J., et al. (2001) · Nature Cell Biology · doi:10.1038/ncb1101-1014 · Cited by 2,752
Cellular and Molecular Regulation of Muscle Regeneration
CHARGÉ, S. B. P., & Rudnicki, M. A. (2004) · Physiological Reviews · doi:10.1152/physrev.00019.2003 · Cited by 2,691
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
Lin, J., Wu, H., Tarr, P. T., Zhang, C.-Y., Wu, Z., Boss, O., Michael, L. F., Puigserver, P., Isotani, E., Olson, E. N., et al. (2002) · Nature · doi:10.1038/nature00904 · Cited by 2,546
FUNCTIONAL SIGNIFICANCE OF CELL SIZE IN SPINAL MOTONEURONS
Henneman, E., Somjen, G., & Carpenter, D. O. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.3.560 · Cited by 2,294
Double muscling in cattle due to mutations in the myostatin gene
McPherron, A. C., & Lee, S.-J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.23.12457 · Cited by 2,039
Fundamentals of Resistance Training: Progression and Exercise Prescription
KRAEMER, W. J., & RATAMESS, N. A. (2004) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000121945.36635.61 · Cited by 1,992 · cited 4×
“past and present resistance exercise prescriptions (Kraemer and Ratamess 2004) still use ambiguous stimulus”
BackgroundInfluential
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.
Stitt, T. N., Drujan, D., Clarke, B. A., Panaro, F., Timofeyva, Y., Kline, W. O., Gonzalez, M., Yancopoulos, G. D., & Glass, D. J. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00211-4 · Cited by 1,964
Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy
Gomes, M. D., Lecker, S. H., Jagoe, R. T., Navon, A., & Goldberg, A. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.251541198 · Cited by 1,774
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
Lecker, S. H., Jagoe, R. T., Gilbert, A., Gomes, M., Baracos, V., Bailey, J., Price, S. R., Mitch, W. E., & Goldberg, A. L. (2004) · The FASEB Journal · doi:10.1096/fj.03-0610com · Cited by 1,539
Myostatin Mutation Associated with Gross Muscle Hypertrophy in a Child
Schuelke, M., Wagner, K. R., Stolz, L. E., Hübner, C., Riebel, T., Kömen, W., Braun, T., Tobin, J. F., & Lee, S.-J. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040933 · Cited by 1,399
Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity
Wang, Y.-X., Lee, C.-H., Tiep, S., Yu, R. T., Ham, J., Kang, H., & Evans, R. M. (2003) · Cell · doi:10.1016/s0092-8674(03)00269-1 · Cited by 1,296
Tensegrity I. Cell structure and hierarchical systems biology
Ingber, D. E. (2003) · Journal of Cell Science · doi:10.1242/jcs.00359 · Cited by 1,266
Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle
Musarò, A., McCullagh, K., Paul, A., Houghton, L., Dobrowolny, G., Molinaro, M., Barton, E. R., L Sweeney, H., & Rosenthal, N. (2001) · Nature Genetics · doi:10.1038/84839 · Cited by 1,137 · cited 5×
“Transgenic mice engineered to overexpress systemic or liver type IGF-1 under the control of a muscle-speciWc promoter have skeletal muscles that are twofold greater in mass than those seen in normal mice (Coleman et al. 1995; Musaro et al. 2001).”
BackgroundMethodInfluential
Mixed muscle protein synthesis and breakdown after resistance exercise in humans
Phillips, S. M., Tipton, K. D., Aarsland, A., Wolf, S. E., & Wolfe, R. R. (1997) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1997.273.1.e99 · Cited by 1,132
Skeletal muscle hypertrophy and atrophy signaling pathways
Glass, D. J. (2005) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2005.04.018 · Cited by 1,106 · cited 2×
“Two pathways downstream of PI3K and Akt are believed to mediate hypertrophy (Glass 2005; Nader 2005): the Akt/mammalian target of rapamycin (mTOR) pathway, and the Akt/glycogen synthase kinase 3 beta (GSK3 ) pathway.”
Background
Regulation of Muscle Fiber Type and Running Endurance by PPARδ
Wang, Y.-X., Zhang, C.-L., Yu, R. T., Cho, H. K., Nelson, M. C., Bayuga-Ocampo, C. R., Ham, J., Kang, H., & Evans, R. M. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020294 · Cited by 1,089
Integration of Oxygen Signaling at the Consensus HRE
Wenger, R. H., Stiehl, D. P., & Camenisch, G. (2005) · Science's STKE · doi:10.1126/stke.3062005re12 · Cited by 1,032
Satellite cells as the source of nuclei in muscles of growing rats
Moss, F. P., & Leblond, C. P. (1971) · The Anatomical Record · doi:10.1002/ar.1091700405 · Cited by 1,025
The Molecular Basis of Skeletal Muscle Atrophy
Jackman, R. W., & Kandarian, S. C. (2004) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00579.2003 · Cited by 1,008 · cited 2×
“several studies have identiWed at least Wve diVerent systems involved in the degradation of proteins during muscle atrophy (Jackman and Kandarian 2004; Kandarian and Jackman 2006).”
Background
The orderly recruitment of human motor units during voluntary isometric contractions
Milner‐Brown, H. S., Stein, R. B., & Yemm, R. (1973) · The Journal of Physiology · doi:10.1113/jphysiol.1973.sp010192 · Cited by 912
Myostatin Inhibits Myoblast Differentiation by Down-regulating MyoD Expression
Langley, B. C., Thomas, M., Bishop, A., Sharma, M., Gilmour, S., & Kambadur, R. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204291200 · Cited by 910
Exercise induces transient transcriptional activation of the PGC‐1α gene in human skeletal muscle
Pilegaard, H., Saltin, B., & Neufer, P. D. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2002.034850 · Cited by 885
Tensegrity II. How structural networks influence cellular information processing networks
Ingber, D. E. (2003) · Journal of Cell Science · doi:10.1242/jcs.00360 · Cited by 852
The Cardiac Mechanical Stretch Sensor Machinery Involves a Z Disc Complex that Is Defective in a Subset of Human Dilated Cardiomyopathy
Knöll, R., Hoshijima, M., Hoffman, H. M., Person, V., Lorenzen-Schmidt, I., Bang, M.-L., Hayashi, T., Shiga, N., Yasukawa, H., Schaper, W., et al. (2002) · Cell · doi:10.1016/s0092-8674(02)01226-6 · Cited by 786
Myostatin negatively regulates satellite cell activation and self-renewal
McCroskery, S., Thomas, M., Maxwell, L., Sharma, M., & Kambadur, R. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200207056 · Cited by 784
New insights into the behavior of muscle during active lengthening
Morgan, D. L. (1990) · Biophysical Journal · doi:10.1016/s0006-3495(90)82524-8 · Cited by 727
Physiological and structural changes in the cat's soleus muscle due to immobilization at different lengths by plaster casts*
Tabary, J. C., Tabary, C., Tardieu, C., TARDIEU, G., & Goldspink, G. (1972) · The Journal of Physiology · doi:10.1113/jphysiol.1972.sp009891 · Cited by 727
Behaviour of human motor units in different muscles during linearly varying contractions
de Luca, C. J., LeFever, R. S., McCue, M. P., & Xenakis, A. P. (1982) · The Journal of Physiology · doi:10.1113/jphysiol.1982.sp014293 · Cited by 719
Signalling pathways that mediate skeletal muscle hypertrophy and atrophy
Glass, D. J. (2003) · Nature Cell Biology · doi:10.1038/ncb0203-87 · Cited by 694
HGF/SF Is Present in Normal Adult Skeletal Muscle and Is Capable of Activating Satellite Cells
Tatsumi, R., Anderson, J. E., Nevoret, C. J., Halevy, O., & Allen, R. E. (1998) · Developmental Biology · doi:10.1006/dbio.1997.8803 · Cited by 685
Regulation of mitochondrial biogenesis in skeletal muscle by CaMK
Wu, H., Kanatous, S. B., Thurmond, F. A., Gallardo, T., Isotani, E., Bassel-Duby, R., & Williams, R. S. (2002) · Science · doi:10.1126/science.1071163 · Cited by 684
Muscle size and strength are increased following walk training with restricted venous blood flow from the leg muscle, Kaatsu-walk training
Abe, T., Kearns, C. F., & Sato, Y. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01267.2005 · Cited by 662
Myoglobin O2 desaturation during exercise. Evidence of limited O2 transport.
Richardson, R. S., Noyszewski, E. A., Kendrick, K. F., Leigh, J. S., & Wagner, P. D. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118237 · Cited by 647
Selective glycogen depletion pattern in human muscle fibres after exercise of varying intensity and at varying pedalling rates
Gollnick, P. D., Piehl, K., & Saltin, B. (1974) · The Journal of Physiology · doi:10.1113/jphysiol.1974.sp010639 · Cited by 643
Myogenic Vector Expression of Insulin-like Growth Factor I Stimulates Muscle Cell Differentiation and Myofiber Hypertrophy in Transgenic Mice
Coleman, M. E., DeMayo, F., Yin, K. C., Lee, H. M., Geske, R., Montgomery, C., & Schwartz, R. J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.20.12109 · Cited by 642
Atrophy of the soleus muscle by hindlimb unweighting
Thomason, D. B., & Booth, F. W. (1990) · Journal of Applied Physiology · doi:10.1152/jappl.1990.68.1.1 · Cited by 631
Selective recruitment of high‐threshold human motor units during voluntary isotonic lengthening of active muscles.
Nardone, A., Romano, C., & Schieppati, M. (1989) · The Journal of Physiology · doi:10.1113/jphysiol.1989.sp017507 · Cited by 612
The Kinase Domain of Titin Controls Muscle Gene Expression and Protein Turnover
Lange, S., Xiang, F., Yakovenko, A. R., Vihola, A., Hackman, P., Rostkova, E. V., Kristensen, J., Brandmeier, B., Franzen, G., Hedberg, B., et al. (2005) · Science · doi:10.1126/science.1110463 · Cited by 602
Comparison of the recruitment and discharge properties of motor units in human brachial biceps and adductor pollicis during isometric contractions
Kukulka, C. G., & Clamann, H. P. (1981) · Brain Research · doi:10.1016/0006-8993(81)90266-3 · Cited by 583
Mechanisms of Exercise-Induced Muscle Fibre Injury
Armstrong, R. B., Warren, G. L., & Warren, J. (1991) · Sports Medicine · doi:10.2165/00007256-199112030-00004 · Cited by 565
Insulin-like Growth Factor-1 (IGF-1) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Pathway
Latres, E., Amini, A. R., Amini, A. A., Griffiths, J., Martin, F. J., Wei, Y., Lin, H. C., Yancopoulos, G. D., & Glass, D. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m407517200 · Cited by 538
Control scheme governing concurrently active human motor units during voluntary contractions
Luca, C. J. D., Lefever, R. S., McCue, M. P., & Xenakis, A. P. (1982) · The Journal of Physiology · doi:10.1113/jphysiol.1982.sp014294 · Cited by 510
Peroxisome proliferator‐activated receptor δ controls muscle development and oxydative capability
Luquet, S., Lopez‐Soriano, J., Holst, D., Fredenrich, A., Melki, J., Rassoulzadegan, M., & Grimaldi, P. A. (2003) · The FASEB Journal · doi:10.1096/fj.03-0269fje · Cited by 509
Rank order of motoneurons within a pool: law of combination.
Henneman, E., Clamann, H. P., Gillies, J. D., & Skinner, R. D. (1974) · Journal of Neurophysiology · doi:10.1152/jn.1974.37.6.1338 · Cited by 490
Stem cells in postnatal myogenesis: molecular mechanisms of satellite cell quiescence, activation and replenishment
Dhawan, J., & Rando, T. A. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.10.007 · Cited by 466
Effects of resistance exercise combined with vascular occlusion on muscle function in athletes
Takarada, Y., Sato, Y., & Ishii, N. (2002) · European Journal of Applied Physiology · doi:10.1007/s00421-001-0561-5 · Cited by 458
Human hamstring muscles adapt to eccentric exercise by changing optimum length
Brockett, C., Morgan, D. L., & Proske, U. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200105000-00017 · Cited by 457
A Role for Nitric Oxide in Muscle Repair: Nitric Oxide–mediated Activation of Muscle Satellite Cells
Anderson, J. E. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.5.1859 · Cited by 455
Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway
Semsarian, C., Wu, M., Ju, Y., Marciniec, T., Yeoh, T., Allen, D. G., Harvey, R. P., & Graham, R. M. (1999) · Nature · doi:10.1038/23054 · Cited by 451
Molecular mechanisms modulating muscle mass
Glass, D. J. (2003) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(03)00138-2 · Cited by 444
Conditional Activation of Akt in Adult Skeletal Muscle Induces Rapid Hypertrophy
Lai, K.-M. V., Gonzalez, M., Poueymirou, W. T., Kline, W. O., Na, E., Zlotchenko, E., Stitt, T. N., Economides, A. N., Yancopoulos, G. D., & Glass, D. J. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.21.9295-9304.2004 · Cited by 442
Changes in human muscle protein synthesis after resistance exercise
Chesley, A., MacDougall, J. D., Tarnopolsky, M. A., Atkinson, S. A., & Smith, K. (1992) · Journal of Applied Physiology · doi:10.1152/jappl.1992.73.4.1383 · Cited by 436
An accurate mass tag strategy for quantitative and high-throughput proteome measurements
Smith, R. D., Anderson, G., Lipton, M. S. W., Paša‐Tolić, L., Shen, Y., Conrads, T. P., Veenstra, T. D., & Udseth, H. R. (2002) · PROTEOMICS · doi:10.1002/1615-9861(200205)2:5 · Cited by 431
Hepatocyte growth factor activates quiescent skeletal muscle satellite cells in vitro
Allen, R. E., Sheehan, S. M., Taylor, R. G., Kendall, T. L., & Rice, G. M. (1995) · Journal of Cellular Physiology · doi:10.1002/jcp.1041650211 · Cited by 422
Stimulation of Slow Skeletal Muscle Fiber Gene Expression by Calcineurin in Vivo
Naya, F. J., Mercer, B. M., Shelton, J. M., Richardson, J. A., Williams, R. S., & Olson, E. N. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.7.4545 · Cited by 420
Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise
Hameed, M., Orrell, R. W., COBBOLD, M., Goldspink, G., & Harridge, S. D. R. (2002) · The Journal of Physiology · doi:10.1111/j.1469-7793.2003.00247.x · Cited by 420
Cellular and Molecular Signatures of Muscle Regeneration: Current Concepts and Controversies in Adult Myogenesis
Wagers, A. J., & Conboy, I. M. (2005) · Cell · doi:10.1016/j.cell.2005.08.021 · Cited by 416
Acute phase response in exercise. III. Neutrophil and IL-1 beta accumulation in skeletal muscle
Fielding, R. A., Manfredi, T., Ding, W., FIATARONE, M. A., Evans, W. J., & Cannon, J. G. (1993) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1993.265.1.r166 · Cited by 415
Intracellular signaling during skeletal muscle atrophy
Kandarian, S. C., & Jackman, R. W. (2005) · Muscle & Nerve · doi:10.1002/mus.20442 · Cited by 405
Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain
Centner, T., Yano, J., Kimura, E., McElhinny, A., Pelin, K., Witt, C. C., Bang, M., Trombitás, K., Granzier, H., Gregorio, C. C., et al. (2001) · Journal of Molecular Biology · doi:10.1006/jmbi.2001.4448 · Cited by 402
A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification
Pallafacchina, G., Calabria, E., Serrano, A. L., Kalhovde, J. M., & Schiaffino, S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.142166599 · Cited by 402
Control of the size of the human muscle mass
Rennie, M. J., Wackerhage, H., Spangenburg, E. E., & Booth, F. W. (2004) · Annual Review of Physiology · doi:10.1146/annurev.physiol.66.052102.134444 · Cited by 399
FIBRILLATION AND FASCICULATION IN VOLUNTARY MUSCLE
DENNY-BROWN, D., & PENNYBACKER, J. B. (1938) · Brain · doi:10.1093/brain/61.3.311 · Cited by 392
Muscle fiber hypertrophy, hyperplasia, and capillary density in college men after resistance training
McCall, G. E., Byrnes, W. C., Dickinson, A., Pattany, P. M., & Fleck, S. J. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.81.5.2004 · Cited by 383
Longitudinal growth of striated muscle fibres
WILLIAMS, P. E., & Goldspink, G. (1971) · Journal of Cell Science · doi:10.1242/jcs.9.3.751 · Cited by 376
Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle
Winder, W. W. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.3.1017 · Cited by 375 · cited 1×
“Further, AMP-activated protein kinase (AMPK) activity has been shown to be increased during contractions and exercise both in rodents and humans (Winder 2001).”
Background
The effects of heavy resistance training and detraining on satellite cells in human skeletal muscles
Kadi, F., Schjerling, P., Andersen, L. L., Charifi, N., Madsen, J. L., Christensen, L. R., & Andersen, J. L. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2004.065904 · Cited by 363
Isoform Diversity of Giant Proteins in Relation to Passive and Active Contractile Properties of Rabbit Skeletal Muscles
Prado, L. G., Makarenko, I. I., Andresen, C., Krüger, M., Opitz, C. A., & Linke, W. A. (2005) · The Journal of General Physiology · doi:10.1085/jgp.200509364 · Cited by 363
The Induction and Decay of Heat Acclimatisation in Trained Athletes
Armstrong, L. E., & Maresh, C. M. (1991) · Sports Medicine · doi:10.2165/00007256-199112050-00003 · Cited by 361
Satellite cells are mitotically quiescent in mature mouse muscle: An EM and radioautographic study
Schultz, E., Gibson, M. C., & Champion, T. (1978) · Journal of Experimental Zoology · doi:10.1002/jez.1402060314 · Cited by 359
The Muscle Ankyrin Repeat Proteins: CARP, ankrd2/Arpp and DARP as a Family of Titin Filament-based Stress Response Molecules
Miller, M. K., Bang, M., Witt, C. C., Labeit, D., Trombitas, C., Watanabe, K., Granzier, H. L. M., McElhinny, A., Gregorio, C. C., & Labeit, S. (2003) · Journal of Molecular Biology · doi:10.1016/j.jmb.2003.09.012 · Cited by 356
Untitled work
(2005) · PubMed · Cited by 354
Variability in Muscle Size and Strength Gain After Unilateral Resistance Training
Shrier, I. (2006) · Yearbook of Sports Medicine · doi:10.1016/s0162-0908(08)70354-4 · Cited by 349
Patterns of gene expression in atrophying skeletal muscles: response to food deprivation
Jagoe, R. T., Lecker, S. H., Gomes, M., & Goldberg, A. L. (2002) · The FASEB Journal · doi:10.1096/fj.02-0312com · Cited by 344
Injury to skeletal muscle fibers during contractions: conditions of occurrence and prevention
Faulkner, J. A., Brooks, S. V., & Opiteck, J. A. (1993) · Physical Therapy · doi:10.1093/ptj/73.12.911 · Cited by 341 · cited 1×
“It is postulated that extensive physical activity, such as resistance training or muscle overloading (chronic stretch, agonist muscle ablation, tenotomy), inXicts muscle injury (Allen et al. 2005; Armstrong et al. 1991; Faulkner et al. 1993; Gibala et al. 1995).”
Background
Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans
Bamman, M. M., Shipp, J. R., Jiang, J., Gower, B. A., Hunter, G. R., Goodman, A. G., McLafferty, C. L., & Urban, R. J. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.280.3.e383 · Cited by 340
The effects of eccentric and concentric training at different velocities on muscle hypertrophy
Farthing, J. P., & Chilibeck, P. D. (2003) · European Journal of Applied Physiology · doi:10.1007/s00421-003-0842-2 · Cited by 339
Activation of insulin-like growth factor gene expression during work-induced skeletal muscle growth
DeVol, D. L., Rotwein, P. S., Sadow, J. L., NOVAKOFSKI, J. E., & Bechtel, P. J. (1990) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1990.259.1.e89 · Cited by 329
Response of Skeletal Muscle Mitochondria to Hypoxia
Hoppeler, H. H., Vogt, M., Weibel, E. R., & Flück, M. (2003) · Experimental Physiology · doi:10.1113/eph8802513 · Cited by 329
Different roles of the IGF‐I Ec peptide (MGF) and mature IGF‐I in myoblast proliferation and differentiation
Yang, S. Y., & Goldspink, G. (2002) · FEBS Letters · doi:10.1016/s0014-5793(02)02918-6 · Cited by 321
Isometric force production by motor units of extensor digitorum communis muscle in man
Monster, A. W., & Chan, H. (1977) · Journal of Neurophysiology · doi:10.1152/jn.1977.40.6.1432 · Cited by 320
Expression and Splicing of the Insulin‐Like Growth Factor Gene in Rodent Muscle is Associated with Muscle Satellite (stem) Cell Activation following Local Tissue Damage
Hill, M., & Goldspink, G. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2002.035832 · Cited by 313
Invited Review: Effects of different activity and inactivity paradigms on myosin heavy chain gene expression in striated muscle
Baldwin, K. M., & Haddad, F. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.1.345 · Cited by 312
Changes in human skeletal muscle ultrastructure and force production after acute resistance exercise
Gibala, M. J., MacDOUGALL, J. D., Tarnopolsky, M. A., Stauber, W. T., & Elorriaga, A. (1995) · Journal of Applied Physiology · doi:10.1152/jappl.1995.78.2.702 · Cited by 310
Spherical reflector as an electromagnetic-missile launcher
Shen, H.-M. (1990) · Journal of Applied Physics · doi:10.1063/1.347115 · Cited by 307
Replicative Potential and Telomere Length in Human Skeletal Muscle: Implications for Satellite Cell-Mediated Gene Therapy
Decary, S., Mouly, V., Hamida, C. B., Sautet, A., Barbet, P., & Butler-Browne, G. S. (1997) · Human Gene Therapy · doi:10.1089/hum.1997.8.12-1429 · Cited by 304
Cloning and characterization of an IGF-1 isoform expressed in skeletal muscle subjected to stretch
Yang, S., Alnaqeeb, M. A., Simpson, H., & Goldspink, G. (1996) · Journal of Muscle Research and Cell Motility · doi:10.1007/bf00123364 · Cited by 296
Effects of Age, Gender, and Myostatin Genotype on the Hypertrophic Response to Heavy Resistance Strength Training
Ivey, F. M., Roth, S. M., Ferrell, R. E., Tracy, B. L., Lemmer, J. T., Hurlbut, D. E., Martel, G. F., Siegel, E. L., Fozard, J. L., Metter, E. J., et al. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.11.m641 · Cited by 288
Connective tissue changes in immobilised muscle.
WILLIAMS, P. E., & Goldspink, G. (1984) · PubMed · Cited by 287
Muscle satellite (stem) cell activation during local tissue injury and repair
Hill, M., Wernig, A., & Goldspink, G. (2003) · Journal of Anatomy · doi:10.1046/j.1469-7580.2003.00195.x · Cited by 286
Release of Hepatocyte Growth Factor from Mechanically Stretched Skeletal Muscle Satellite Cells and Role of pH and Nitric Oxide
Tatsumi, R., Hattori, A., Ikeuchi, Y., Anderson, J. E., & Allen, R. E. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-01-0062 · Cited by 279
Global analysis of gene expression patterns during disuse atrophy in rat skeletal muscle
Stevenson, E. J., Giresi, P. G., Koncarevic, A., & Kandarian, S. C. (2003) · The Journal of Physiology · doi:10.1111/j.1469-7793.2003.00033.x · Cited by 278
Calcineurin Is Required for Skeletal Muscle Hypertrophy
Dunn, S. E., Burns, J. L., & Michel, R. N. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.31.21908 · Cited by 278
Acetylcholine receptors and myasthenia
Lindstrom, J. M. (2000) · Muscle & Nerve · doi:10.1002/(sici)1097-4598(200004)23:4 · Cited by 277
Physiological activation of hypoxia inducible factor‐1 in human skeletal muscle
Ameln, H., Gustafsson, T., Sundberg, C. J., Okamoto, K., Jansson, E., Poellinger, L., & Makino, Y. (2005) · The FASEB Journal · doi:10.1096/fj.04-2304fje · Cited by 276
Effect of varying exercise intensity on glycogen depletion in human muscle fibres
Vøllestad, N. K., & BLOM, P. C. S. (1985) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1985.tb07735.x · Cited by 274
Decline running produces more sarcomeres in rat vastus intermedius muscle fibers than does incline running
Lynn, R., & Morgan, D. L. (1994) · Journal of Applied Physiology · doi:10.1152/jappl.1994.77.3.1439 · Cited by 271
Exercise-induced satellite cell activation in growing and mature skeletal muscle
Darr, K. C., & Schultz, E. (1987) · Journal of Applied Physiology · doi:10.1152/jappl.1987.63.5.1816 · Cited by 268
Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1
McElhinny, A., Kakinuma, K., Sorimachi, H., Labeit, S., & Gregorio, C. C. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200108089 · Cited by 265
PGC-1α mRNA expression is influenced by metabolic perturbation in exercising human skeletal muscle
Norrbom, J., Sundberg, C. J., Rundqvist, H., Kraus, W. E., Jansson, E., & Gustafsson, T. P. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00765.2003 · Cited by 263
IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle
Chakravarthy, M. V., Davis, B. S., & Booth, F. W. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.4.1365 · Cited by 262
Shift of activity from slow to fast muscle during voluntary lengthening contractions of the triceps surae muscles in humans.
Nardone, A., & Schieppati, M. (1988) · The Journal of Physiology · doi:10.1113/jphysiol.1988.sp016924 · Cited by 260
cDNA Cloning and mRNA Analysis of PGC-1 in Epitrochlearis Muscle in Swimming-Exercised Rats
Goto, M., Terada, S., Kato, M., Katoh, M., Yokozeki, T., Tabata, I., & Shimokawa, T. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3134 · Cited by 258
Gamma irradiation prevents compensatory hypertrophy of overloaded mouse extensor digitorum longus muscle
Rosenblatt, J. D., & Parry, D. J. (1992) · Journal of Applied Physiology · doi:10.1152/jappl.1992.73.6.2538 · Cited by 252
Nuclear domains in muscle cells
Hall, Z. W., & Ralston, E. (1989) · Cell · doi:10.1016/0092-8674(89)90597-7 · Cited by 249
The Time Course for Elevated Muscle Protein Synthesis Following Heavy Resistance Exercise
MacDougall, J. D., Gibala, M. J., Tarnopolsky, M. A., MacDonald, J. R., Interisano, S. A., & Yarasheski, K. E. (1995) · Canadian Journal of Applied Physiology · doi:10.1139/h95-038 · Cited by 248 · cited 1×
“The importance of these three factors (x6, x12, x5, Table 1) has been demonstrated in studies, in which the duration of elevated protein turnover following resistance exercise sessions was investigated (Chesley et al. 1992; MacDougall et al. 1995; Phillips et al. 1997).”
Background
Mass spectrometry: A tool for the identification of proteins separated by gels
Lahm, H., & Langen, H. (2000) · Electrophoresis · doi:10.1002/1522-2683(20000601)21:11 · Cited by 240
Insulin-like Growth Factor-I Extends in VitroReplicative Life Span of Skeletal Muscle Satellite Cells by Enhancing G1/S Cell Cycle Progression via the Activation of Phosphatidylinositol 3′-Kinase/Akt Signaling Pathway
Chakravarthy, M. V., Abraha, T. W., Schwartz, R. J., Fiorotto, M. L., & Booth, F. W. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m005832200 · Cited by 239
Chemotaxis of skeletal muscle satellite cells
Bischoff, R. (1997) · Developmental Dynamics · doi:10.1002/(sici)1097-0177(199704)208:4 · Cited by 232
Role of Ca2+/calmodulin-dependent kinases in skeletal muscle plasticity
Chin, E. R. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00015.2005 · Cited by 229
Cellular and molecular responses to increased skeletal muscle loading after irradiation.
Adams, G., Caiozzo, V., Haddad, F., & Baldwin, K. (2002) · American Journal of Physiology - Cell Physiology · doi:10.1152/ajpcell.00173.2002 · Cited by 227
Mechanical Stretch Induces Activation of Skeletal Muscle Satellite Cells in Vitro
Tatsumi, R., Sheehan, S. M., Iwasaki, H., Hattori, A., & Allen, R. E. (2001) · Experimental Cell Research · doi:10.1006/excr.2001.5252 · Cited by 224
Gene expression in skeletal muscle in response to stretch and force generation
Goldspink, G., Scutt, A. M., Loughna, P. T., Wells, D. J., Jaenicke, T., & Gerlach, G. F. (1992) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1992.262.3.r356 · Cited by 223
Motor unit control properties in constant-force isometric contractions
Luca, C. J. D., Foley, P. J., & Erim, Z. (1996) · Journal of Neurophysiology · doi:10.1152/jn.1996.76.3.1503 · Cited by 222
Loss of Skeletal Muscle HIF-1α Results in Altered Exercise Endurance
Mason, S. D., Howlett, R. A., Kim, M. J., Olfert, I. M., Hogan, M. C., McNulty, W., Hickey, R. P., Wagner, P. D., Kahn, C. R., Giordano, F. J., et al. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020288 · Cited by 210
Molecular regulation of individual skeletal muscle fibre types
Spangenburg, E. E., & Booth, F. W. (2003) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2003.01158.x · Cited by 208
Akt signaling in skeletal muscle: regulation by exercise and passive stretch
Sakamoto, K., Aschenbach, W. G., Hirshman, M. F., & Goodyear, L. J. (2003) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00228.2003 · Cited by 207
Mechanisms of stretch‐induced muscle damage in normal and dystrophic muscle: role of ionic changes
Allen, D. G., Whitehead, N. P., & Yeung, E. W. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.091694 · Cited by 206
Neuromuscular adaptations in human muscle following low intensity resistance training with vascular occlusion
Moore, D. R., Burgomaster, K. A., Schofield, L., Gibala, M. J., SALE, D. G., & Phillips, S. M. (2004) · European Journal of Applied Physiology · doi:10.1007/s00421-004-1072-y · Cited by 199
Short-term high- vs. low-velocity isokinetic lengthening training results in greater hypertrophy of the elbow flexors in young men
Shepstone, T. N., Tang, J. E., Dallaire, S., Schuenke, M. D., Staron, R. S., & Phillips, S. M. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01027.2004 · Cited by 199
Muscle glycogen depletion patterns in type I and subgroups of type II fibres during prolonged severe exercise in man
Vøllestad, N. K., VAAGE, O., & Hermansen, L. (1984) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1984.tb07531.x · Cited by 198
Differences in rat skeletal muscles after incline and decline running
Lynn, R., Talbot, J. A., & Morgan, D. L. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.85.1.98 · Cited by 196
Selected contribution: acute cellular and molecular responses to resistance exercise.
Haddad, F., & Adams, G. (2002) · Journal of applied physiology · doi:10.1152/japplphysiol.01153.2001 · Cited by 192
Mechanical Signals, IGF-I Gene Splicing, and Muscle Adaptation
Goldspink, G. (2005) · Physiology · doi:10.1152/physiol.00004.2005 · Cited by 191
Selective glycogen depletion in skeletal muscle fibres of man following sustained contractions
Gollnick, P. D., Karlsson, J., Piehl, K., & Saltin, B. (1974) · The Journal of Physiology · doi:10.1113/jphysiol.1974.sp010640 · Cited by 190
Effects of anabolic steroids on the muscle cells of strength-trained athletes
KADI, F., ERIKSSON, A., HOLMNER, S., & THORNELL, L.-E. (1999) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199911000-00006 · Cited by 190
Cellular adaptation of the trapezius muscle in strength-trained athletes
Kadi, F., Eriksson, A., Holmner, S., Butler-Browne, G. S., & Thornell, L. E. (1999) · Histochemistry and Cell Biology · doi:10.1007/s004180050348 · Cited by 189
SATELLITE CELL REGULATION FOLLOWING MYOTRAUMA CAUSED BY RESISTANCE EXERCISE
Vierck, J. L., O'Reilly, B. A., HOSSNER, K. L., António, J., Byrne, K. M., Bucci, L. R., & Dodson, M. V. (2000) · Cell Biology International · doi:10.1006/cbir.2000.0499 · Cited by 189
Cooperative Effects of Exercise and Occlusive Stimuli on Muscular Function in Low-Intensity Resistance Exercise with Moderate Vascular Occlusion
Takarada, Y., Tsuruta, T., & Ishii, N. (2004) · The Japanese Journal of Physiology · doi:10.2170/jjphysiol.54.585 · Cited by 188
Molecular determinants of skeletal muscle mass: getting the “AKT” together
Nader, G. A. (2005) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2005.02.026 · Cited by 184
POPPING SARCOMERE HYPOTHESIS EXPLAINS STRETCH‐INDUCED MUSCLE DAMAGE
Morgan, D. L., & Proske, U. (2004) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2004.04029.x · Cited by 180
Recruitment order of motor units in human vastus lateralis muscle is maintained during fatiguing contractions
Adam, A., & De Luca, C. J. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00179.2003 · Cited by 178
Mechanical signal transduction in skeletal muscle growth and adaptation
Tidball, J. G. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01178.2004 · Cited by 174
Skeletal muscle intracellular P o 2assessed by myoglobin desaturation: response to graded exercise
Richardson, R. S., Newcomer, S. C., & Noyszewski, E. A. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.6.2679 · Cited by 167
Differential serial sarcomere number adaptations in knee extensor muscles of rats is contraction type dependent
Butterfield, T. A., Leonard, T. R., & Herzog, W. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00481.2005 · Cited by 160
Response of rat muscle to acute resistance exercise defined by transcriptional and translational profiling
Chen, Y., Nader, G. A., Baar, K. R., Fedele, M. J., Hoffman, E. P., & Esser, K. A. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2002.021220 · Cited by 158
Myogenic Akt Signaling Regulates Blood Vessel Recruitment during Myofiber Growth
Takahashi, A., Kureishi, Y., Jiang, Y., Luo, Z., Guo, K. Y., Mukhopadhyay, D., Ivashchenko, Y., Branellec, D., & Walsh, K. X. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.13.4803-4814.2002 · Cited by 157
Molecular and Cellular Determinants of Skeletal Muscle Atrophy and Hypertrophy
Sartorelli, V., & Fulco, M. (2004) · Science s STKE · doi:10.1126/stke.2442004re11 · Cited by 155
Skeletal Muscle Satellite Cell Characteristics in Young and Older Men and Women After Heavy Resistance Strength Training
Roth, S. M., Martel, G. F., Ivey, F. M., Lemmer, J. T., Tracy, B. L., Metter, E. J., Hurley, B. F., & Rogers, M. A. (2001) · The Journals of Gerontology Series A · doi:10.1093/gerona/56.6.b240 · Cited by 152
Rapid muscle-specific gene expression changes after a single bout of eccentric contractions in the mouse
Barash, I. A., Mathew, L., Ryan, A. F., Chen, J., & Lieber, R. L. (2004) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00211.2003 · Cited by 148
Muscle fiber number in biceps brachii in bodybuilders and control subjects
MacDOUGALL, J. D., SALE, D. G., Alway, S. E., & Sutton, J. R. (1984) · Journal of Applied Physiology · doi:10.1152/jappl.1984.57.5.1399 · Cited by 144
Different modes of hypertrophy in skeletal muscle fibers
Paul, A. C., & Rosenthal, N. A. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200105147 · Cited by 142
Fatigue management
Mock, V. (2001) · Cancer · doi:10.1002/1097-0142(20010915)92:6+ · Cited by 140
The control of cell mass and replication. The DNA unit - a personal 20-year study
Cheek, D. B. (1985) · Early Human Development · doi:10.1016/0378-3782(85)90144-6 · Cited by 139
Satellite cell response in rat soleus muscle undergoing hypertrophy due to surgical ablation of synergists
Snow, M. H. (1990) · The Anatomical Record · doi:10.1002/ar.1092270407 · Cited by 137
Reactivity of Au with ultrathin Si layers: A photoemission study
Ivančo, J., Kobayashi, H., Almeida, J., Margaritondo, G., & Pinčík, E. (2001) · Journal of Applied Physics · doi:10.1063/1.1372658 · Cited by 137
Myosin mRNA accumulation and myofibrillogenesis at the myotendinous junction of stretched muscle fibers.
Dix, D. J., & Eisenberg, B. R. (1990) · The Journal of Cell Biology · doi:10.1083/jcb.111.5.1885 · Cited by 136
Cardiac Ankyrin Repeat Protein Is a Novel Marker of Cardiac Hypertrophy
Aihara, Y., Kurabayashi, M., Saito, Y., Ohyama, Y., Tanaka, T., Takeda, S., Tomaru, K., Sekiguchi, K., Arai, M., Nakamura, T., et al. (2000) · Hypertension · doi:10.1161/01.hyp.36.1.48 · Cited by 135
The fate of newly formed satellite cells during compensatory muscle hypertrophy
Schiaffino, S., Pierobon Bormioli, S., & Aloisi, M. (1976) · Virchows Archiv B Cell Pathology · doi:10.1007/bf02899148 · Cited by 132
Identification of Ankrd2, a Novel Skeletal Muscle Gene Coding for a Stretch-Responsive Ankyrin-Repeat Protein
Kemp, T. J., Sadusky, T. J., Saltisi, F., Carey, N., Moss, J., Yang, S., Sassoon, D. A., Goldspink, G., & Coulton, G. R. (2000) · Genomics · doi:10.1006/geno.2000.6213 · Cited by 127
Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in murine cardiogenesis
Kuo, H.-C., Chen, J., Ruiz‐Lozano, P., Zou, Y., Nemer, M. J., & Chien, K. R. (1999) · Development · doi:10.1242/dev.126.19.4223 · Cited by 127
Frequent Sequence Variation in the Human Myostatin (GDF8) Gene as a Marker for Analysis of Muscle-Related Phenotypes
Ferrell, R. E., Conte, V., Lawrence, E., Roth, S. M., Hagberg, J. M., & Hurley, B. F. (1999) · Genomics · doi:10.1006/geno.1999.5984 · Cited by 125
Recruitment of motor units in voluntary contraction of a finger muscle in man
Tanji, J., & Κato, M. (1973) · Experimental Neurology · doi:10.1016/0014-4886(73)90110-6 · Cited by 118
Influence of exercise intensity on ERK/MAP kinase signalling in human skeletal muscle
Widegren, U., Wretman, C., Lionikas, A., Hedin, G., & Henriksson, J. (2000) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s004240000417 · Cited by 118
Half-Sarcomere Dynamics in Myofibrils during Activation and Relaxation Studied by Tracking Fluorescent Markers
Telley, I. A., Denoth, J., Stüssi, E., Pfitzer, G., & Stehle, R. (2005) · Biophysical Journal · doi:10.1529/biophysj.105.070334 · Cited by 116
C-Met Expression and Mechanical Activation of Satellite Cells on Cultured Muscle Fibers
Wozniak, A. C., Pilipowicz, O., Yablonka‐Reuveni, Z., Greenway, S. C., Craven, S., Scott, E., & Anderson, J. E. (2003) · Journal of Histochemistry & Cytochemistry · doi:10.1177/002215540305101104 · Cited by 112
Effect of exercise intensity and hypoxia on skeletal muscle AMPK signaling and substrate metabolism in humans
Wadley, G. D., Lee, R. S., Canny, B. J., Wasuntarawat, C., Chen, Z. P., Hargreaves, M., Kemp, B. E., & McConell, G. K. (2005) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00464.2005 · Cited by 111
Ballistic Movement: Muscle Activation and Neuromuscular Adaptation
Zehr, E. P., & SALE, D. G. (1994) · Canadian Journal of Applied Physiology · doi:10.1139/h94-030 · Cited by 109
Calcineurin and skeletal muscle growth
Michel, R. N., Dunn, S. E., & Chin, E. R. (2004) · Proceedings of The Nutrition Society · doi:10.1079/pns2004362 · Cited by 107
Effect of the thiol-oxidizing agent diamide on NH2Cl-induced rat colonic electrolyte secretion
Tamai, H., Kachur, J. F., Grisham, M. B., Musch, M. W., Chang, E. B., & Gaginella, T. S. (1993) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1993.265.1.c166 · Cited by 107
Malleability of the motor system: a comparative approach
Goldspink, G. (1985) · Journal of Experimental Biology · doi:10.1242/jeb.115.1.375 · Cited by 106
Patterns of global gene expression in rat skeletal muscle during unloading and low-intensity ambulatory activity
Bey, L., Akunuri, N., Zhao, P., Hoffman, E. P., Hamilton, D. G., & Hamilton, M. T. (2003) · Physiological Genomics · doi:10.1152/physiolgenomics.00001.2002 · Cited by 106
Distribution of myosin heavy chain isoforms in non-weight-bearing rat soleus muscle fibers
Talmadge, R. J., Roy, R. R., & Edgerton, V. R. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.81.6.2540 · Cited by 104
Regulation of skeletal muscle fiber size, shape and function
Edgerton, V. R., & Roy, R. R. (1991) · Journal of Biomechanics · doi:10.1016/0021-9290(91)90383-x · Cited by 104
Genotype Associations With Increases In Blood Creatine Kinase And Myoglobin Following Intense Eccentric Exercise: 883 Board #105 9:00 AM ??? 10:30 AM
Hubal, M. J., Hoffman, E. P., Devaney, J. M., Gordish-Dressman, H., Kearns, A., Zambraski, E., & Clarkson, P. M. (2005) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200505001-00881 · Cited by 104
Production of rat muscle atrophy by cast fixation.
Booth, F. W., & Kelso, J. R. (1973) · Journal of Applied Physiology · doi:10.1152/jappl.1973.34.3.404 · Cited by 101
Stretch and force generation induce rapid hypertrophy and myosin isoform gene switching in adult skeletal muscle
Goldspink, G., Scutt, A. M., Martindale, J., Jaenicke, T., Turay, L., & Gerlach, G.-F. (1991) · Biochemical Society Transactions · doi:10.1042/bst0190368 · Cited by 101
Activation of muscle satellite cells in single-fiber cultures
Anderson, J. E., & Pilipowicz, O. (2002) · Nitric Oxide · doi:10.1016/s1089-8603(02)00011-3 · Cited by 99
Dynamic behaviour of half‐sarcomeres during and after stretch in activated rabbit psoas myofibrils: sarcomere asymmetry but no ‘sarcomere popping’
Telley, I. A., Stehle, R., Ranatunga, K. W., Pfitzer, G., Stüssi, E., & Denoth, J. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.105809 · Cited by 98
Single-fiber myosin heavy chain polymorphism: how many patterns and what proportions?
Caiozzo, V. J., Baker, M. J., Huang, K., Chou, H., Wu, Y. Z., & Baldwin, K. M. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00646.2002 · Cited by 95
Active hepatocyte growth factor is present in skeletal muscle extracellular matrix
Tatsumi, R., & Allen, R. E. (2004) · Muscle & Nerve · doi:10.1002/mus.20114 · Cited by 94
Eccentric exercise markedly increases c-Jun NH 2 -terminal kinase activity in human skeletal muscle
Boppart, M. D., Aronson, D., Gibson, L., Roubenoff, R., Abad, L. W., Bean, J. F., Goodyear, L. J., & Fielding, R. A. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.87.5.1668 · Cited by 93
Accumulation of Muscle Ankyrin Repeat Protein Transcript Reveals Local Activation of Primary Myotube Endcompartments during Muscle Morphogenesis
Baumeister, A., Arber, S., & Caroni, P. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.5.1231 · Cited by 93
Prolonged unloading of rat soleus muscle causes distinct adaptations of the gene profile
Wittwer, M., Flück, M., Hoppeler, H. H., Müller, S., Dominique Desplanches, C., & Billeter-Clark, R. (2002) · The FASEB Journal · doi:10.1096/fj.01-0792fje · Cited by 91
Mechanical overload and skeletal muscle fiber hyperplasia: a meta-analysis
Kelley, G. A. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.81.4.1584 · Cited by 91
Characterization of control and immobilized skeletal muscle: an overview from genetic engineering
St‐Amand, J., Okamura, K., Matsumoto, K., SHIMIZU, S., & Sogawa, Y. (2001) · The FASEB Journal · doi:10.1096/fj.00-0150com · Cited by 90
Exercise Stimulates c-Jun NH2Kinase Activity and c-Jun Transcriptional Activity in Human Skeletal Muscle
Aronson, D., Boppart, M. D., Dufresne, S. D., Fielding, R. A., & Goodyear, L. J. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9435 · Cited by 89
Forkhead transcription factor FoxO1 transduces insulin‐like growth factor's signal to p27Kip1 in primary skeletal muscle satellite cells
Machida, S., Spangenburg, E. E., & Booth, F. W. (2003) · Journal of Cellular Physiology · doi:10.1002/jcp.10339 · Cited by 88
Glycogen breakdown in different human muscle fibre types during exhaustive exercise of short duration
VØILLESTAD, N. K., Tabata, I., & Medbø, J. I. (1992) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1992.tb09278.x · Cited by 86
Aging-related satellite cell differentiation defect occurs prematurely after Ski-induced muscle hypertrophy
CHARGÉ, S. B. P., Brack, A. S., & Hughes, S. M. (2002) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00206.2002 · Cited by 86
Exploration of myostatin polymorphisms and the angiotensin-converting enzyme insertion/deletion genotype in responses of human muscle to strength training
Thomis, M. A., Huygens, W., Heuninckx, S., Chagnon, M., MAES, H. H. M., Claessens, A., VLIETINCK, R. F., Bouchard, C., & Beunen, G. P. (2004) · European Journal of Applied Physiology · doi:10.1007/s00421-004-1093-6 · Cited by 85
Functional Polymorphisms Associated with Human Muscle Size and Strength
Thompson, P. D., Moyna, N. M., Seip, R. L., Price, T. B., Clarkson, P. M., Angelopoulos, T. J., Gordon, P. M., Pescatello, L. S., Visich, P. S., Zoeller, R. F., et al. (2004) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000132274.26612.23 · Cited by 77
Exercise-induced mitogen-activated protein kinase signalling in skeletal muscle
Long, Y. C., Widegren, U., & Zierath, J. R. (2004) · Proceedings of The Nutrition Society · doi:10.1079/pns2004346 · Cited by 75
Region of Longitudinal Growth in Striated Muscle Fibres
Griffin, G. E., WILLIAMS, P. E., & Goldspink, G. (1971) · Nature New Biology · doi:10.1038/newbio232028a0 · Cited by 74
Functional adaptation of sarcomere number of normal cat muscle.
Jc, T., Tardieu, C., TARDIEU, G., Tabary, C., & Gagnard, L. (1976) · PubMed · Cited by 74
Energy metabolism pathways in rat muscle under conditions of simulated microgravity
Stein, T. P., Schluter, M. D., Galante, A. T., Soteropoulos, P., Tolias, P. P., Grindeland, R. E., Moran, M., Wang, T. J., Polansky, M., & Wade, C. E. (2002) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(02)00195-x · Cited by 70
Powerful Genes — Myostatin Regulation of Human Muscle Mass
McNally, E. M. (2004) · New England Journal of Medicine · doi:10.1056/nejmp048124 · Cited by 67
Molecular Identification and Characterization of a Novel Nuclear Protein Whose Expression Is Up-regulated in Insulin-resistant Animals
Ikeda, K., Emoto, N., Matsuo, M., & Yokoyama, M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m204563200 · Cited by 66
Stress‐dependent and ‐independent expression of the myogenic regulatory factors and the MARP genes after eccentric contractions in rats
Hentzen, E. R., Lahey, M., Peters, D., Mathew, L., Barash, I. A., Fridén, J. O., & Lieber, R. L. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.093005 · Cited by 65
Satellite cells of the rat soleus muscle in the process of compensatory hypertrophy combined with denervation
Hanzl�kov�, V. R., Mackov�, E., & Hn�k, P. (1975) · Cell and Tissue Research · doi:10.1007/bf00222049 · Cited by 64
Effects of inactivity on fiber size and myonuclear number in rat soleus muscle
Zhong, H., Roy, R. R., Siengthai, B., & Edgerton, V. R. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00394.2005 · Cited by 63
Muscle tissue oxygenation, pressure, electrical, and mechanical responses during dynamic and static voluntary contractions
Vedsted, P., Blangsted, A. K., Søgaard, K., Orizio, C., & Sjøgaard, G. (2004) · European Journal of Applied Physiology · doi:10.1007/s00421-004-1216-0 · Cited by 62
Adaptation of connective tissue length to immobilization in the lengthened and shortened positions in cat soleus muscle.
Tardieu, C., Tabary, J. C., Tabary, C., & TARDIEU, G. (1982) · PubMed · Cited by 61

Research works printed but not linked: 2

Bowtell J, Park DM, Smith K, Cuthbertson DJR, Waddell T, Rennie MJ (2003) Stimulation of human quadriceps protein synthesis after strenous exercise: no effects of varying intensity between 60 and 90% of one repetition maximum (1RM). J Physiol (Lond) 547P:P16
Schiaffino S, Bormioli SP, Aloisi M (1979) Fibre branching and formation of new fibres during compensatory muscle hypertrophy. In: Mauro A (ed) Muscle regeneration. Raven, New York, pp 177–188

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Authors: Toigo, M., & Boutellier, U.
Affiliations: University of Zurich (CH)
Corresponding author: Toigo, Marco
Venue: European Journal of Applied Physiology
Publisher: Springer Science and Business Media LLC
Published: 2006-07-15
Volume: 97
Issue: 6
Pages: 643-663
ISSN: 0020-9376 (ISSN-L)
1439-6319
1439-6327
DOI: 10.1007/s00421-006-0238-1
OpenAlex: W1981567469
Cited by: 437
References: 229
Citations by year: 2026: 12 · 2025: 22 · 2024: 18 · 2023: 35 · 2022: 49 · 2021: 35 · 2020: 47 · 2019: 25 · 2018: 37 · 2017: 26 · 2016: 20 · 2015: 31 · 2014: 14 · 2013: 18 · 2012: 12
FWCI: 0.87
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: European Journal of Applied Physiology (publishedVersion)
PubMed (publishedVersion)
Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, other-oa)
reroDoc Digital Library (submittedVersion)
Repository for Publications and Research Data (ETH Zurich) (submittedVersion, other-oa)
Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
ETH Zürich Research Collection
Zurich Open Repository and Archive (University of Zurich)
Topics: Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Keywords: resistance training, skeletal muscle adaptation, exercise prescription, time under tension, muscular failure, range of motion
MeSH terms: Adaptation, Physiological, Animals, Humans, Models, Biological, Signal Transduction, Exercise, Muscle, Skeletal, Muscle Cells, Satellite Cells, Skeletal Muscle, Cell Enlargement

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New fundamental resistance exercise determinants of molecular and cellular muscle adaptations

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