New insights onto cardiopulmonary nematodes of dogs in Sardinia, Italy
Abstract
Dog heartworms Angiostrongylus vasorum and Dirofilaria immitis cause severe parasitological diseases; the importance of these parasitosis is growing due to their health impact on animals, the possible zoonotic implications and the recent spreading across several European countries and previously non-endemic areas. The aim of this study is to update the epidemiological scenario of cardiopulmonary nematodes A. vasorum and D. immitis in dogs of Sardinia island and to perform a morphological identification of larvae by the use of the Baermann and Knott techniques respectively and the molecular characterization of the mitochondrial cytochrome c oxidase subunit I (cox1) and the second ribosomal transcribed spacer region (ITS-2) of larvae L1 of A. vasorum. In the present study, 3.4% (5/146) of dogs resulted positive at Baermann technique for A. vasorum while 8.9% (61/684) to D. immitis. If on one side A. vasorum can be considered an emerging parasite in Sardinia, the parasitic pressure and the risk of infection for D. immitis in the island seems to be increased compared with the recent past.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In Giglio and Sardinia, canine heartworm prevalence was 2.4% and 8.9%, respectively, and on Linosa and Lampedusa islands D. immitis was detected at 58.9%.
“Finally, the prevalence in Giglio and Sardinia were 2.4 and 8.9%, respectively [29,39]. In addition, on the Linosa and Lampedusa islands, D. immitis was detected at 58.9% [40].”
From What has happened to heartworm disease in Europe in the last 10 years? (2022) · cites this paper as [39]
Dirofilaria immitis is present not only in the hyperendemic area of the Po River Valley but also from northern to southern regions of the Italian peninsula, including islands where the infection is now endemic.
“Today D. immitis is present not only in the hyperendemic area of the Po River Valley [3, 16], but from northern to southern regions of Italian peninsula as reviewed in Otranto et al. [17], including islands [18] where the infection is now endemic.”
From Dirofilaria immitis and Angiostrongylus vasorum: the contemporaneous detection in kennels (2015) · cites this paper as [18]
Cites
Canine and feline cardiopulmonary parasitic nematodes in Europe: emerging and underestimated
Traversa, D., Di Cesare, A., & Conboy, G. (2010) · Parasites & Vectors · doi:10.1186/1756-3305-3-62 · Cited by 351 · see citing works
Climate and Dirofilaria infection in Europe
Genchi, C., Rinaldi, L., Mortarino, M., Genchi, M., & Cringoli, G. (2009) · Veterinary parasitology · doi:10.1016/j.vetpar.2009.03.026 · Cited by 349 · cited 1× · see citing works
“In Italy, current data on canine dirofilariasis confirms the expanding trend of this parasite as observed in the rest of Europe (Genchi et al. 2009).”
BackgroundIs heartworm disease really spreading in Europe?
Genchi, C., Rinaldi, L., Cascone, C., Mortarino, M., & Cringoli, G. (2005) · Veterinary Parasitology · doi:10.1016/j.vetpar.2005.04.009 · Cited by 222 · see citing works
Dirofilarial Infections in Europe
Genchi, C., Kramer, L. H., & Rivasi, F. (2011) · Vector-Borne and Zoonotic Diseases · doi:10.1089/vbz.2010.0247 · Cited by 214 · see citing works
Barutzki, D., & Schaper, R. (2011) · Parasitology Research · doi:10.1007/s00436-011-2402-8 · Cited by 204 · see citing works
Magnis, J., Lorentz, S., Guardone, L., Grimm, F., Magi, M., Naucke, T. J., & Deplazes, P. (2013) · Parasites & Vectors · doi:10.1186/1756-3305-6-48 · Cited by 169 · see citing works
Helminth Parasites of the Canine and Feline Respiratory Tract
Conboy, G. (2009) · Veterinary Clinics of North America: Small Animal Practice · doi:10.1016/j.cvsm.2009.06.006 · Cited by 166 · see citing works
Canine pulmonary angiostrongylosis: The influence of climate on parasite distribution
Morgan, E. R., Jefferies, R., Krajewski, M., Ward, P., & Shaw, S. E. (2009) · Parasitology International · doi:10.1016/j.parint.2009.08.003 · Cited by 149 · see citing works
Gastrointestinal parasites of shepherd and hunting dogs in the Serres Prefecture, Northern Greece
Papazahariadou, M., Founta, A., Papadopoulos, E., Chliounakis, S., Antoniadou-Sotiriadou, K., & Theodorides, Y. (2007) · Veterinary Parasitology · doi:10.1016/j.vetpar.2007.05.013 · Cited by 146 · see citing works
Traversa, D., & Guglielmini, C. (2008) · Veterinary Parasitology · doi:10.1016/j.vetpar.2008.07.020 · Cited by 144 · see citing works
Canine angiostrongylosis: an emerging disease in Europe
Helm, J. R., Morgan, E. R., Jackson, M. W., Wotton, P., & Bell, R. (2010) · Journal of Veterinary Emergency and Critical Care · doi:10.1111/j.1476-4431.2009.00494.x · Cited by 116 · see citing works
Natural Infections of Angiostrongylus vasorum and Crenosoma vulpis in Dogs in Germany (2007–2009)
Barutzki, D., & Schaper, R. (2009) · Parasitology Research · doi:10.1007/s00436-009-1494-x · Cited by 93 · see citing works
Canine and Feline Infections by Cardiopulmonary Nematodes in Central and Southern Italy
Di Cesare, A., Castagna, G., Meloni, S., Milillo, P., Latrofa, S., Otranto, D., & Traversa, D. (2011) · Parasitology Research · doi:10.1007/s00436-011-2405-5 · Cited by 82 · see citing works
Schnyder, M., & Deplazes, P. (2012) · Parasites & Vectors · doi:10.1186/1756-3305-5-258 · Cited by 80 · see citing works
Angiostrongylus vasorumfrom South America and Europe represent distinct lineages
JEFFERIES, R., Shaw, S. E., Viney, M., & Morgan, E. R. (2009) · Parasitology · doi:10.1017/s0031182008005258 · Cited by 71 · see citing works
Traversa, D., Aste, G., Milillo, P., Capelli, G., Pampurini, F., Tunesi, C., Santori, D., Paoletti, B., & Boari, A. (2010) · Veterinary Parasitology · doi:10.1016/j.vetpar.2009.12.034 · Cited by 71 · see citing works
Brianti, E., Otranto, D., Dantas-Torres, F., Weigl, S., Latrofa, M. S., Gaglio, G., Napoli, E., Brucato, G., Cauquil, L., Giannetto, S., et al. (2012) · Veterinary Parasitology · doi:10.1016/j.vetpar.2011.07.031 · Cited by 64 · see citing works
Self-citationEvidences of increasing risk of dirofilarioses in southern Italy
Giangaspero, A., Marangi, M., Latrofa, M. S., Martinelli, D., Traversa, D., Otranto, D., & Genchi, C. (2013) · Parasitology Research · doi:10.1007/s00436-012-3206-1 · Cited by 58 · see citing works
Guardone, L., Schnyder, M., Macchioni, F., Deplazes, P., & Magi, M. (2013) · Veterinary Parasitology · doi:10.1016/j.vetpar.2012.10.016 · Cited by 56 · see citing works
Autochthonous Angiostrongylus vasorum infection in dogs in The Netherlands
van Doorn, D. C. K., van de Sande, A. H., Nijsse, E. R., Eysker, M., & Ploeger, H. W. (2009) · Veterinary Parasitology · doi:10.1016/j.vetpar.2009.02.019 · Cited by 50 · see citing works
Traversa, D., Di Cesare, A., Meloni, S., Frangipane di Regalbono, A., Milillo, P., Pampurini, F., & Venco, L. (2013) · Parasitology Research · doi:10.1007/s00436-013-3412-5 · Cited by 50 · see citing works
Otranto, D., Varcasia, A., Solinas, C., Scala, A., Brianti, E., Dantas‐Torres, F., Annoscia, G., Martin, C., Mutafchiev, Y., & Bain, O. (2013) · Parasites & Vectors · doi:10.1186/1756-3305-6-132 · Cited by 41 · see citing works
Self-citationIDENTIFICATION OF CANINE MICROFILARIAE.
Lindsey, J. R. (1965) · PubMed · Cited by 38 · see citing works
Canine filarial infections in Tuscany, central Italy
Magi, M., Guardone, L., Prati, M. C., Tozzini, G., Torracca, B., Monni, G., & Macchioni, F. (2012) · Journal of Helminthology · doi:10.1017/s0022149x11000113 · Cited by 27 · see citing works
Diagnostic experimental des helminthoses animales
Gevrey, J. (1984) · Veterinary Parasitology · doi:10.1016/0304-4017(84)90053-0 · Cited by 22 · see citing works
Cercopithifilaria spp. in dogs in Sardinia Island (Italy)
Solinas, C., Varcasia, A., Brianti, E., Giannetto, S., Pipia, A. P., Columbano, N., Tosciri, G., Dantas‐Torres, F., Garippa, G., Otranto, D., et al. (2013) · Parasitology Research · doi:10.1007/s00436-013-3695-6 · Cited by 18 · see citing works
Self-citationDirofilaria immitis: a zoonosis of clinical concern.
Levine, S., Mossler, J. A., & Woodard, B. H. (1980) · PubMed · Cited by 13 · see citing works
LEVINE, S. E., MOSSLER, J. A., & Woodard, B. H. (1980) · Southern Medical Journal · doi:10.1097/00007611-198006000-00020 · Cited by 8 · see citing works
Canine Angiostrongylus vasorum
Moeremans, I., Binst, D. H. A. R., Claerebout, E., de Maele, I. V., & Daminet, S. (2011) · Vlaams Diergeneeskundig Tijdschrift · doi:10.21825/vdt.87284 · Cited by 5 · see citing works
Canine Filariosis in Sardinia: Epidemiological Findings in the Ogliastra Region
Scala, A., Solinas, C., Pipia, A. P., Sanna, G., Varcasia, A., & Tosciri, G. (2013) · Springer eBooks · doi:10.1007/978-3-642-36488-4_14 · Cited by 4 · see citing works
Self-citation[Filariasis in dogs in Sardinia].
Arru, E., Nuvole, A., & Mann, P. (1969) · PubMed · Cited by 2 · see citing works
Dirofilariosi canina: un esempio di federalismo parassitario
Pietrobelli, M., Rossi, L., Genchi, C., Poglayen, G., Macchioni, F., Magi, M., Diaferia, M., Veronesi, F., Cancrini, G., Traversa, D., et al. (2010) · Padua Research Archive (University of Padova) · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
What has happened to heartworm disease in Europe in the last 10 years?
Morchón, R., Montoya-Alonso, J. A., Rodríguez-Escolar, I., & Carretón, E. (2022) · Pathogens · doi:10.3390/pathogens11091042 · Cited by 69 · see citing works
Occurrence of canine and feline extra-intestinal nematodes in key endemic regions of Italy
Traversa, D., Morelli, S., Cassini, R., Crisi, P. E., Russi, I., Grillotti, E., Manzocchi, S., Simonato, G., Beraldo, P., Viglietti, A., et al. (2019) · Acta Tropica · doi:10.1016/j.actatropica.2019.03.009 · Cited by 58 · see citing works
Piantedosi, D., Neola, B., D’Alessio, N., Prisco, F. D., Santoro, M., Pacifico, L., Sgroi, G., Auletta, L., Buch, J. S., Chandrashekar, R., et al. (2017) · Parasitology Research · doi:10.1007/s00436-017-5574-z · Cited by 49 · see citing works
Canine angiostrongylosis: recent advances in diagnosis, prevention, and treatment
Cesare, A. D., & Traversa, D. (2014) · Veterinary medicine · doi:10.2147/vmrr.s53641 · Cited by 41 · see citing works
Tamponi, C., Varcasia, A., Pinna, S., Melis, E., Melosu, V., Zidda, A., Sanna, G., Pipia, A. P., Zedda, M. T., Pau, S., et al. (2017) · Veterinary Parasitology Regional Studies and Reports · doi:10.1016/j.vprsr.2017.07.001 · Cited by 30 · see citing works
Self-citationAngiostrongylus vasorum: epidemiological, clinical and histopathological insights
Rinaldi, L., Cortese, L., Meomartino, L., Pagano, T. B., Pepe, P., Cringoli, G., & Papparella, S. (2014) · BMC Veterinary Research · doi:10.1186/s12917-014-0236-1 · Cited by 27 · see citing works
Gizzarelli, M., Manzillo, V. F., Ciucă, L., Morgoglione, M. E., Fayala, N. E. H. B., Cringoli, G., Oliva, G., Rinaldi, L., & Maurelli, M. P. (2019) · Frontiers in Veterinary Science · doi:10.3389/fvets.2019.00288 · Cited by 23 · see citing works
Fuehrer, H., Morelli, S., Bleicher, J., Brauchart, T., Edler, M., Eisschiel, N., Hering, T., Lercher, S., Mohab, K., Reinelt, S., et al. (2020) · Pathogens · doi:10.3390/pathogens9121046 · Cited by 21 · see citing works
Dirofilaria immitis and Angiostrongylus vasorum: the contemporaneous detection in kennels
Del Prete, L., Maurelli, M. P., Pennacchio, S., Bosco, A., Musella, V., Ciuca, L., Cringoli, G., & Rinaldi, L. (2015) · BMC Veterinary Research · doi:10.1186/s12917-015-0619-y · Cited by 19 · see citing works
Olivieri, E., Zanzani, S. A., Gazzonis, A. L., Giudice, C., Brambilla, P., Alberti, I., Romussi, S., Lombardo, R., Mortellaro, C. M., Banco, B., et al. (2017) · BMC Veterinary Research · doi:10.1186/s12917-017-1083-7 · Cited by 16 · see citing works
Serological and molecular detection of Leishmania infantum in cats of Northern Sardinia, Italy
Dedola, C., Zobba, R., Varcasia, A., Visco, S., Alberti, A., Pipia, A. P., Scala, A., & Parpaglia, M. L. P. (2018) · Veterinary Parasitology Regional Studies and Reports · doi:10.1016/j.vprsr.2018.05.003 · Cited by 14 · see citing works
Self-citationCorda, A., Carta, S., Varcasia, A., Tamponi, C., Evangelisti, M. A., Scala, A., & Pinna Parpaglia, M. L. (2019) · Parasites & Vectors · doi:10.1186/s13071-019-3544-2 · Cited by 13 · see citing works
Self-citationCanine filarial infections in Liguria, north-west Italy
Magi, M., Guardone, L., Mignone, W., Monni, G., Tozzini, G., Prati, M. C., & Macchioni, F. (2015) · Journal of Helminthology · doi:10.1017/s0022149x15000012 · Cited by 12 · see citing works
Simultaneous Exposure to Angiostrongylus vasorum and Vector-Borne Pathogens in Dogs from Italy
Morelli, S., Gori, F., Colombo, M., Traversa, D., Sarrocco, G., Simonato, G., Nespeca, C., Di Cesare, A., Frangipane di Regalbono, A., Veronesi, F., et al. (2021) · Pathogens · doi:10.3390/pathogens10091200 · Cited by 11 · see citing works
Teixeira, R., Flor, I., Nunes, T., Pinto, C., Pomba, M. C., & de Carvalho, L. M. (2024) · Pathogens · doi:10.3390/pathogens13080648 · Cited by 10 · see citing works
Cardio-pulmonary nematodes of the red fox (Vulpes vulpes) of Sardinia, Italy
Nonnis, F., Tamponi, C., Tosciri, G., Manconi, M., Pudda, F., Cabras, P., Dessì, G., Scala, A., & Varcasia, A. (2023) · Parasitology Research · doi:10.1007/s00436-023-07882-8 · Cited by 6 · see citing works
Self-citationMehlhorn, H. (2015) · Springer eBooks · doi:10.1007/978-3-642-27769-6_4575-1
Mehlhorn, H. (2016) · Springer eBooks · doi:10.1007/978-3-662-43978-4_4575
Travelling safe? Risks associated to Dirofilaria spp. infection in dogs in a tourist destination
Nonnis, F., Atzeni, D., Cavallo, L., Gabrielli, S., Pombi, M., Cavallero, S., Bellini, I., Napoli, E., Benedetto, G. D., Venco, L., et al. (2025) · Current Research in Parasitology and Vector-Borne Diseases · doi:10.1016/j.crpvbd.2025.100298
Self-citation
- Authors
- Pipia, A. P., Varcasia, A., Tosciri, G., Seu, S., Manunta, M. L., Mura, M. C., Sanna, G., Tamponi, C., Brianti, E., & Scala, A.
- Affiliations
- University of Sassari (IT)
- University of Messina (IT)
- Corresponding author
- Varcasia, A.
- Venue
- Parasitology Research
- Published
- 2014-02-14
- Volume
- 113
- Issue
- 4
- Pages
- 1505-1509
- ISSN
- 0044-3255 (ISSN-L)
- 0932-0113
- 1432-1955
- OpenAlex
- W2016932876
- Cited by
- 19
- References
- 32
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 3 · 2018: 1 · 2017: 3 · 2016: 1 · 2015: 3 · 2014: 2
- FWCI
- 4.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Parasitology Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Mollusks and Parasites Studies
- Keywords
- Angiostrongylus vasorum, Dirofilaria immitis, canine heartworm disease, dogs, Sardinia, emerging parasitic disease, zoonoses, larval identification, mitochondrial COI, ITS2, molecular identification
- MeSH terms
- Angiostrongylus, Animals, Dirofilaria immitis, Dirofilariasis, Dog Diseases, Dogs, Female, Heart Diseases, Italy, Larva, Male, Prevalence, Strongylida Infections
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
