Variation in Vocal-Motor Development in Infant Siblings of Children with Autism
Open accessAbstract
In this study we examined early motor, vocal, and communicative development in a group of younger siblings of children diagnosed with autism (Infant Siblings). Infant Siblings and no-risk comparison later-born infants were videotaped at home with a primary caregiver each month from 5 to 14 months, with follow-up at 18 months. As a group, Infant Siblings were delayed in the onset of early developmental milestones and spent significantly less time in a greater number of postures, suggestive of relative postural instability. In addition, they demonstrated attenuated patterns of change in rhythmic arm activity around the time of reduplicated babble onset; and they were highly likely to exhibit delayed language development at 18 months.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
At older ages, deficits in more complex aspects of development may become more apparent.
“At older ages, deficits in more complex aspects of development may become more apparent (e.g., the onset of walking [47]).”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works
Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005592401947 · Cited by 7,520 · see citing works
Journal of Consciousness Studies
(2022) · Journal of Consciousness Studies · doi:10.53765/20512201 · Cited by 6,852 · see citing works
American Journal of Mental Retardation
Staff (2008) · Encyclopedia of Special Education · doi:10.1002/9780470373699.speced0106 · Cited by 2,972 · see citing works
Handbook of Autism and Pervasive Developmental Disorders
(2005) · Wiley eBooks · doi:10.1002/9780470939352 · Cited by 2,252 · see citing works
Behavioral manifestations of autism in the first year of life
Zwaigenbaum, L., Bryson, S., Rogers, T., Roberts, W., Brian, J., & Szatmari, P. (2005) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2004.05.001 · Cited by 1,602 · see citing works
Exploring complexity: an introduction
Nicolis, G., & Prigogine, I. (1990) · Choice Reviews Online · doi:10.5860/choice.27-4495 · Cited by 1,245 · see citing works
Baranek, G. T. (1999) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1023080005650 · Cited by 1,027 · see citing works
Campos, J. J., Anderson, D. I., Barbu‐Roth, M. A., Hubbard, E. M., Hertenstein, M. J., & Witherington, D. C. (2000) · Infancy · doi:10.1207/s15327078in0102_1 · Cited by 970 · see citing works
Infants with autism: an investigation of empathy, pretend play, joint attention, and imitation
Charman, T., Swettenham, J., Baron-Cohen, S., Cox, A., Baird, G., & Drew, A. (1997) · Developmental Psychology · doi:10.1037/0012-1649.33.5.781 · Cited by 813 · see citing works
Genetics of austim: complex aetiology for a heterogeneous disorder
Folstein, S. E., & Rosen-Sheidley, B. (2001) · Nature Reviews Genetics · doi:10.1038/35103559 · Cited by 771 · see citing works
Development in infants with autism spectrum disorders: a prospective study
Landa, R., & Garrett‐Mayer, E. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01531.x · Cited by 730 · see citing works
A Neurological Model for Childhood Autism
Damásio, A. R., & Maurer, R. G. (1978) · Archives of Neurology · doi:10.1001/archneur.1978.00500360001001 · Cited by 729 · see citing works
Movement analysis in infancy may be useful for early diagnosis of autism
Teitelbaum, P., Teitelbaum, O., Nye, J., Fryman, J., & Maurer, R. G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.23.13982 · Cited by 713 · see citing works
Parental recognition of developmental abnormalities in autism
GIACOMO, A. D., & Fombonne, E. J. (1998) · European Child & Adolescent Psychiatry · doi:10.1007/s007870050058 · Cited by 596 · see citing works
Rhythmical stereotypies in normal human infants
Thelen, E. (1979) · Animal Behaviour · doi:10.1016/0003-3472(79)90006-x · Cited by 577 · see citing works
Motor Assessment of the Developing Infant
Hurran, C. (1995) · Physiotherapy · doi:10.1016/s0031-9406(05)67120-9 · Cited by 540 · see citing works
Principles of Brain Functioning
Haken, H. (1996) · Springer series in synergetics · doi:10.1007/978-3-642-79570-1 · Cited by 535 · see citing works
MITCHELL, S., BRIAN, J., ZWAIGENBAUM, L., ROBERTS, W., SZATMARI, P., SMITH, I., & BRYSON, S. (2006) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200604002-00004 · Cited by 535 · see citing works
Motor Assessment of the Developing Infant
Piper, M. C., & Darrah, J. (1994) · Medical Entomology and Zoology · Cited by 477 · see citing works
Autism: The Phenotype in Relatives
Bailey, A. J., Palferman, S., Heavey, L., & Couteur, A. S. L. (1998) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1026048320785 · Cited by 453 · see citing works
Underdevelopment of the postural control system in autism
Minshew, N. J., Sung, K., Jones, B. L., & Furman, J. M. (2004) · Neurology · doi:10.1212/01.wnl.0000145771.98657.62 · Cited by 440 · see citing works
Language and Communication in Autism
Kim, S. H., Paul, R., Tager-Flusberg, H. B., & Lord, C. (2014) · doi:10.1002/9781118911389.hautc10 · Cited by 392 · see citing works
The Articulatory Basis of Babbling
Davis, B. L., & MacNeilage, P. F. (1995) · Journal of Speech Language and Hearing Research · doi:10.1044/jshr.3806.1199 · Cited by 363 · see citing works
Principles of brain functioning: a synergetic approach to brain activity, behavior and cognition
(1996) · Choice Reviews Online · doi:10.5860/choice.34-0287 · Cited by 352 · see citing works
Predicting spoken language level in children with autism spectrum disorders
Stone, W. L., & Yoder, P. J. (2001) · Autism · doi:10.1177/1362361301005004002 · Cited by 340 · cited 6× · see citing works
“In a review of the early medical screening records of 18-month-old children eventually diagnosed with ASD, Johnson, Siddons, Frith, and Morton (1992) observed a marginal tendency for greater problems in motor development for this group relative to randomly selected children eventually identified as having learning dis…”
BackgroundInfluentialYirmiya, N., Seidman, I., Pilowsky, T., Feldman, R., Baron‐Cohen, S., & Sigman, M. (2005) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2005.01528.x · Cited by 329 · see citing works
Comparison of Asperger syndrome and high-functioning autistic children on a Test of Motor Impairment
Manjiviona, J., & Prior, M. R. (1995) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02178165 · Cited by 328 · see citing works
Precursors to speech in infancy
Oller, D. K., Eilers, R. E., Neal, A., et al. (1999) · Journal of Communication Disorders · doi:10.1016/s0021-9924(99)00013-1 · Cited by 302 · see citing works
Zwaigenbaum, L., Thurm, A., Stone, W., Baranek, G., Bryson, S., Iverson, J., Kau, A., Klin, A., Lord, C., Landa, R., et al. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0179-x · Cited by 297 · see citing works
Self-citationMoving on: autism and movement disturbance.
Leary, M. R., & Hill, D. A. (1996) · PubMed · Cited by 275 · see citing works
Movement Analysis in Infancy May Be Useful for Early Diagnosis of Autism
Teitelbaum, P., Teitelbaum, O., Nye, J., Fryman, J., & Maurer, R. G. (1998) · Cited by 270 · see citing works
Gait Disturbances in Patients With Autistic Behavior
Vilensky, J. A. (1981) · Archives of Neurology · doi:10.1001/archneur.1981.00510100074013 · Cited by 268 · see citing works
(1989) · American Journal of Psychiatry · doi:10.1176/ajp.146.8.1032 · Cited by 255 · cited 1× · see citing works
“Group Patterns of Delay Relative to the general population, those infants with an older sibling already diagnosed with autism are known to be at more than 200 times the risk for an eventual ASD diagnosis themselves (Ritvo et al., 1989; see Zwaigenbaum et al., 2005, for more recent figures).”
BackgroundGenetics of Autism: Overview and New Directions
Szatmari, P., Jones, M. B., Zwaigenbaum, L., & MacLean, J. E. (1998) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1026096203946 · Cited by 249 · see citing works
Genetic influence on language delay in two-year-old children
Dale, P. S., Simonoff, E. A., Bishop, D., Eley, T. C., Oliver, B. R., Price, T. S., Purcell, S., Stevenson, J., & Plomin, R. J. (1998) · Nature Neuroscience · doi:10.1038/1142 · Cited by 244 · see citing works
Prespeech and early speech development of two late talkers
Stoel‐Gammon, C. (1989) · First Language · doi:10.1177/014272378900900607 · Cited by 242 · see citing works
THE HANDICAPS OF AUTISTIC CHILDREN—A COMPARATIVE STUDY
Wing, L. (1969) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1969.tb02066.x · Cited by 231 · see citing works
Motor imitation abilities and neurological signs in autistic children
Jones, V., & Prior, M. R. (1985) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01837897 · Cited by 222 · see citing works
Handbook of autism and pervasive developmental disorders, 2nd ed.
Cohen, D. J., & Volkmar, F. R. (1997) · Cited by 217 · see citing works
International Review of Research in Mental Retardation
Bernstein, N. R. (2001) · Cited by 216 · see citing works
Case Study of the Development of an Infant with Autism from Birth to Two Years of Age
Dawson, G., Osterling, J., Meltzoff, A. N., & Kuhl, P. K. (2000) · Journal of Applied Developmental Psychology · doi:10.1016/s0193-3973(99)00042-8 · Cited by 215 · see citing works
Goal Directed Locomotion and Balance Control in Autistic Children
Vernazza-Martin, S., Martin, N., Vernazza, A. Q., Pellec, A. L., Rufo, M., Massion, J., & Assaiante, C. (2005) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-004-1037-3 · Cited by 176 · see citing works
Attention, Development, and Psychopathology
Merrill, E. C., & Atwell, J. A. (1998) · American Journal on Mental Retardation · doi:10.1352/0895-8017(1998)103 · Cited by 170 · see citing works
Autism and family home movies: Preliminary findings
Adrien, J. L., Faure, M., Perrot, A., HAMEURY, L., Garreau, B., Barthélémy, C., & SAUVAGE, D. (1991) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02206996 · Cited by 158 · see citing works
Infant Vocal–Motor Coordination: Precursor to the Gesture–Speech System?
Iverson, J. M., & Fagan, M. K. (2004) · Child Development · doi:10.1111/j.1467-8624.2004.00725.x · Cited by 153 · see citing works
Self-citationEarly Concerns of Parents of Children With Autistic and Nonautistic Disorders
Coonrod, E. E., & Stone, W. L. (2004) · Infants & Young Children · doi:10.1097/00001163-200407000-00007 · Cited by 143 · see citing works
Co‐occurences of preverbal vocal behavior and motor action in early infancy
Ejiri, K., & Masataka, N. (2001) · Developmental Science · doi:10.1111/1467-7687.00147 · Cited by 123 · see citing works
Stone, W. L. (1994) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1994.02170020060010 · Cited by 111 · see citing works
Adrien, J. L., Perrot, A., SAUVAGE, D., Leddet, I. I. D., Larmande, C., HAMEURY, L., & Barthélémy, C. (1992) · PubMed · Cited by 103 · see citing works
Relationship between Rhythmic Behavior and Canonical Babbling in Infant Vocal Development
Ejiri, K. (1998) · Phonetica · doi:10.1159/000028434 · Cited by 101 · see citing works
Iverson, J. M., Hall, A. J., Nickel, L. R., & Wozniak, R. H. (2006) · Brain and Language · doi:10.1016/j.bandl.2006.11.004 · Cited by 96 · see citing works
Self-citationHand Preference and Motor Functioning in Children with Autism
Hauck, J. A., & Dewey, D. (2001) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1010791118978 · Cited by 93 · see citing works
Diagnosis of autism before the age of 3
Rogers, S. J. (2000) · International review of research in mental retardation · doi:10.1016/s0074-7750(00)80004-x · Cited by 84 · see citing works
Cobo-Lewis, A. B., Oller, D. K., Lynch, M. P., et al. (1996) · PubMed · Cited by 71 · see citing works
Cognitive and verbal abilities of 24- to 36-month-old siblings of children with autism
Yirmiya, N., Gamliel, I., Shaked, M., & Sigman, M. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0163-5 · Cited by 67 · see citing works
Language abilities of siblings of children with autism
Pilowsky, T., Yirmiya, N., Shalev, R. S., & Gross‐Tsur, V. (2003) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00175 · Cited by 57 · see citing works
CAN AUTISM BE PREDICTED ON THE BASIS OF INFANT SCREENING TESTS?
Johnson, M. H., Siddons, F., Uta Frith, A., & Morton, J. (1992) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.1992.tb11435.x · Cited by 50 · see citing works
Stockman, I. J. (2004) · Cited by 34 · see citing works
Early symptoms in autism from family home movies.
Adrien, J. L. (1992) · Acta paedopsychiatrica · Cited by 31 · see citing works
Spence, M. A. (2001) · Current Opinion in Pediatrics · doi:10.1097/00008480-200112000-00012 · Cited by 29 · see citing works
Language is More than Speech: A Case Study.
Gernsbacher, M. A. (2004) · PubMed · Cited by 19 · see citing works
Flagged first, then by citations
Research works printed but not linked: 5
- Fenson L, Dale P, Reznick SJ, Thal DJ, Bates E, Hartung JP, Pethick S, Reilly JS. The MacArthur Communicative Development Inventories: User’s guide and technical manual. San Diego: Singular Press; 1993. [Google Scholar]
- Gernsbacher MA, Goldsmith HH, O’Reilly M, Sauer E, DeRuyter J, Blanc M. Infant motor dyspraxia as a predictor of speech in childhood autism; Poster presented at the International Conference on Infant Studies; Toronto, Ontario, Canada. 2002. [Google Scholar]
- Iverson JM. Increased manual rhythmicity precedes babble onset; Poster presented at the Biennial Meetings of the Society for Research in Child Development; Atlanta, GA. 2005. [Google Scholar]
- Kroeker R. Unpublished doctoral dissertation. Department of Psychology, University of Washington; 2000. Rhythmic behaviors in typically developing infants, and infants with later diagnosed autism or developmental delay. [Google Scholar]
- Siegel B. Pervasive Developmental Disorder Screening Test-II. San Antonio, TX: Harcourt Assessment; 2001. [Google Scholar]
Cited by
Sorted by citations
Developmental pathways to autism: A review of prospective studies of infants at risk
Jones, E. J. H., Gliga, T., Bedford, R., Charman, T., & Johnson, M. H. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.12.001 · Cited by 607 · see citing works
Zwaigenbaum, L., Bryson, S., Lord, C., Rogers, S., Carter, A., Carver, L., Chawarska, K., Constantino, J., Dawson, G., Dobkins, K., et al. (2009) · Pediatrics · doi:10.1542/peds.2008-1606 · Cited by 444 · see citing works
Self-citationResearch Review: Structural language in autistic spectrum disorder – characteristics and causes
Boucher, J. (2012) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2011.02508.x · Cited by 382 · see citing works
Early identification of autism spectrum disorders
Zwaigenbaum, L., Bryson, S., & Garon, N. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.04.004 · Cited by 370 · see citing works
What are infant siblings teaching us about autism in infancy?
Rogers, S. J. (2009) · Autism Research · doi:10.1002/aur.81 · Cited by 351 · see citing works
Developmental Trajectories in Children With and Without Autism Spectrum Disorders: The First 3 Years
Landa, R. J., Gross, A. L., Stuart, E. A., & Faherty, A. (2013) · Child Development · doi:10.1111/j.1467-8624.2012.01870.x · Cited by 316 · see citing works
Diagnosis of autism spectrum disorders in the first 3 years of life
Landa, R. J. (2008) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0731 · Cited by 273 · see citing works
Neural correlates of eye gaze processing in the infant broader autism phenotype
Elsabbagh, M., Volein, A., Csibra, G., Holmboe, K., Garwood, H., Tucker, L., Krljes, S., Baron-Cohen, S., Bolton, P., Charman, T., et al. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.034 · Cited by 206 · see citing works
Jones, E. J. H., Venema, K., Earl, R., Lowy, R., Barnes, K., Estes, A., Dawson, G., & Webb, S. J. (2016) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-016-9139-8 · Cited by 164 · see citing works
“, the onset of walking [47]).”
McCleery, J. P., Akshoomoff, N., Dobkins, K. R., & Carver, L. J. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.07.031 · Cited by 155 · see citing works
Maternal verbal responses to communication of infants at low and heightened risk of autism
Leezenbaum, N. B., Campbell, S. B., Butler, D., & Iverson, J. M. (2014) · Autism · doi:10.1177/1362361313491327 · Cited by 140 · see citing works
Self-citationSpeech-and-gesture integration in high functioning autism
Silverman, L. B., Bennetto, L., Campana, E., & Tanenhaus, M. K. (2010) · Cognition · doi:10.1016/j.cognition.2010.01.002 · Cited by 92 · see citing works
Alpha Asymmetry in Infants at Risk for Autism Spectrum Disorders
Gabard-Durnam, L., Tierney, A. L., Vogel-Farley, V., Tager-Flusberg, H., & Nelson, C. A. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-013-1926-4 · Cited by 85 · see citing works
Advances in the early detection of autism
Zwaigenbaum, L. (2010) · Current Opinion in Neurology · doi:10.1097/wco.0b013e3283372430 · Cited by 64 · see citing works
Venuti, P., Caria, A., Esposito, G., De Pisapia, N., Bornstein, M. H., & de Falco, S. (2012) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2012.06.011 · Cited by 48 · see citing works
Valagussa, G., Trentin, L., Balatti, V., & Grossi, E. (2017) · Autism Research · doi:10.1002/aur.1796 · Cited by 9 · see citing works
Camia, M., Sacco, R., Boncoddo, M., Bellomo, F., Cucinotta, F., Ricciardello, A., Turriziani, L., Tomaiuolo, P., Costantini, R. C., D'Amico, R., et al. (2024) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2024.102457 · Cited by 9 · see citing works
- Authors
- Iverson, J. M., & Wozniak, R. H.
- Affiliations
- University of Pittsburgh (US)
- Bryn Mawr College (US)
- Corresponding author
- Iverson, Jana M.
- ORCID
- Iverson, Jana M.
- Venue
- Journal of Autism and Developmental Disorders
- Published
- 2006-12-27
- Volume
- 37
- Issue
- 1
- Pages
- 158-170
- ISSN
- 0162-3257 (ISSN-L)
- 1573-3432
- PMC
- PMC3521582
- OpenAlex
- W2101504362
- Cited by
- 322
- References
- 62
- Citations by year
- 2026: 3 · 2025: 10 · 2024: 8 · 2023: 6 · 2022: 54 · 2021: 14 · 2020: 47 · 2019: 12 · 2018: 16 · 2017: 15 · 2016: 17 · 2015: 18 · 2014: 15 · 2013: 19 · 2012: 19
- FWCI
- 2.75
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Autism and Developmental Disorders (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01HD035469, HD35469, R01HD041607, U19HD035469, R01 HD 41607, R01HD054979)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Language Development and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- autism spectrum disorder, motor development, communication development, developmental milestones, postural instability, language delay, sibling risk
- MeSH terms
- Autistic Disorder, Communication Disorders, Female, Follow-Up Studies, Humans, Infant, Language Development Disorders, Male, Mass Screening, Periodicity, Posture, Speech Disorders, Verbal Behavior, Prevalence, Stereotypic Movement Disorder, Motor Skills Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review