Advances in the early detection of autism
Abstract
PURPOSE OF REVIEW: Early detection and diagnosis of autism spectrum disorders (ASDs) allows opportunities for children and their families to benefit more fully from early supports and interventions. RECENT FINDINGS: Recent advances in early detection research have resulted from prospective studies of high-risk infants and large ASD screening studies conducted in community settings. With improvement in early detection of autism, exciting progress has been made in establishing the efficacy of ASD-specific interventions for toddlers as young as 18 months on the basis of controlled clinical trials. SUMMARY: There has been increasing emphasis on opportunities to link early behavioral expression to the underlying neurobiology of ASD, potentially bringing us closer to the fundamental mechanisms underlying this disorder.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
ASD cannot be reliably diagnosed in the newborn period or even in the first year of life even in countries where there is considerable awareness of the disorder.
“Because ASD cannot be reliably diagnosed in the newborn period or even in the first year of life even in countries where there is considerable awareness of the disorder,18, 19”
From Social communication difficulties and autism in previously institutionalized children (2015) · cites this paper as [19]
Cites
Dawson, G., Rogers, S., Munson, J., Smith, M., Winter, J., Greenson, J., Donaldson, A., & Varley, J. (2010) · Pediatrics · doi:10.1542/peds.2009-0958 · Cited by 2,621 · see citing works
Identification and Evaluation of Children With Autism Spectrum Disorders
Johnson, C. P., Myers, S. M., & and the Council on Children With Disabilities (2007) · Pediatrics · doi:10.1542/peds.2007-2361 · Cited by 2,011 · see citing works
Structural Variation of Chromosomes in Autism Spectrum Disorder
Marshall, C. R., Noor, A., Vincent, J. B., Lionel, A. C., Feuk, L., Skaug, J., Shago, M., Moessner, R., Pinto, D., Ren, Y., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.12.009 · Cited by 1,815 · see citing works
Self-citationRobins, D. L., Fein, D., Barton, M. L., & Green, J. A. (2001) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1010738829569 · Cited by 1,563 · see citing works
Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder
Dawson, G. (2008) · Development and Psychopathology · doi:10.1017/s0954579408000370 · Cited by 1,138 · see citing works
Prevalence of autism-spectrum conditions: UK school-based population study
Baron-Cohen, S., Scott, F. J., Allison, C., Williams, J., Bolton, P., Matthews, F. E., & Brayne, C. (2009) · British Journal of Psychiatry · doi:10.1192/bjp.bp.108.059345 · Cited by 918 · see citing works
Prevalence of Parent-Reported Diagnosis of Autism Spectrum Disorder Among Children in the US, 2007
Kogan, M. D., Blumberg, S. J., Schieve, L. A., Boyle, C. A., Perrin, J. M., Ghandour, R. M., Singh, G. K., Strickland, B. B., Trevathan, E., & van Dyck, P. C. (2009) · Pediatrics · doi:10.1542/peds.2009-1522 · Cited by 892 · see citing works
Can Autism be Detected at 18 Months?
Baron‐Cohen, S., Allen, J., & Gillberg, C. (1992) · The British Journal of Psychiatry · doi:10.1192/bjp.161.6.839 · Cited by 861 · see citing works
Development in infants with autism spectrum disorders: a prospective study
Landa, R., & Garrett‐Mayer, E. (2006) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2006.01531.x · Cited by 730 · see citing works
Early Indicators of Autism Spectrum Disorders in the Second Year of Life
Wetherby, A. M., Woods, J. J., Allen, L., Cleary, J., Dickinson, H., & Lord, C. (2004) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-004-2544-y · Cited by 629 · see citing works
Shattuck, P. T., Durkin, M., Maenner, M., Newschaffer, C., Mandell, D. S., Wiggins, L., Lee, L.-C., Rice, C., Giarelli, E., Kirby, R., et al. (2009) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e31819b3848 · Cited by 623 · see citing works
Pivotal Response Intervention I: Overview of Approach
Koegel, L. K., Koegel, R. L., Harrower, J. K., & Carter, C. M. (1999) · Research and Practice for Persons with Severe Disabilities · doi:10.2511/rpsd.24.3.174 · Cited by 508 · see citing works
The diagnosis of autism and Asperger syndrome: findings from a survey of 770 families
Howlin, P., & Asgharian, A. (1999) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162299001656 · Cited by 500 · see citing works
Luyster, R., Gotham, K., Guthrie, W., Coffing, M., Petrak, R., Pierce, K., Bishop, S., Esler, A., Hus, V., Oti, R., et al. (2009) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-009-0746-z · Cited by 468 · see citing works
A prospective case series of high-risk infants who developed autism
Bryson, S. E., Zwaigenbaum, L., Brian, J., Roberts, W., Szatmari, P., Rombough, V., & McDermott, C. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0328-2 · Cited by 455 · see citing works
Self-citationZwaigenbaum, L., Bryson, S., Lord, C., Rogers, S., Carter, A., Carver, L., Chawarska, K., Constantino, J., Dawson, G., Dobkins, K., et al. (2009) · Pediatrics · doi:10.1542/peds.2008-1606 · Cited by 444 · see citing works
Self-citationWetherby, A. M., Watt, N., Morgan, L., & Shumway, S. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0237-4 · Cited by 403 · see citing works
Young, G. S., Merin, N., Rogers, S. J., & Ozonoff, S. (2009) · Developmental Science · doi:10.1111/j.1467-7687.2009.00833.x · Cited by 368 · see citing works
What are infant siblings teaching us about autism in infancy?
Rogers, S. J. (2009) · Autism Research · doi:10.1002/aur.81 · Cited by 351 · see citing works
Can one hour per week of therapy lead to lasting changes in young children with autism?
Vismara, L. A., Colombi, C., & Rogers, S. J. (2009) · Autism · doi:10.1177/1362361307098516 · Cited by 331 · see citing works
Variation in Vocal-Motor Development in Infant Siblings of Children with Autism
Iverson, J. M., & Wozniak, R. H. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0339-z · Cited by 322 · see citing works
Atypical object exploration at 12 months of age is associated with autism in a prospective sample
Ozonoff, S., Macari, S., Young, G. S., Goldring, S., Thompson, M., & Rogers, S. J. (2008) · Autism · doi:10.1177/1362361308096402 · Cited by 321 · see citing works
Early communication development and intervention for children with autism
Landa, R. J. (2007) · Mental Retardation and Developmental Disabilities Research Reviews · doi:10.1002/mrdd.20134 · Cited by 314 · see citing works
Zwaigenbaum, L., Thurm, A., Stone, W., Baranek, G., Bryson, S., Iverson, J., Kau, A., Klin, A., Lord, C., Landa, R., et al. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0179-x · Cited by 297 · see citing works
Self-citationThe onset of autism: patterns of symptom emergence in the first years of life
Ozonoff, S., Heung, K., Byrd, R., Hansen, R., & Hertz‐Picciotto, I. (2008) · Autism Research · doi:10.1002/aur.53 · Cited by 293 · see citing works
Wetherby, A. M., Brosnan-Maddox, S., Peace, V., & Newton, L. (2008) · Autism · doi:10.1177/1362361308094501 · Cited by 287 · see citing works
An Effective Day Treatment Model for Young Children with Pervasive Developmental Disorders
ROGERS, S. J., & LEWIS, H. (1989) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-198903000-00010 · Cited by 283 · see citing works
Response to Joint Attention in Toddlers at Risk for Autism Spectrum Disorder: A Prospective Study
Sullivan, M., Finelli, J., Marvin, A., Garrett-Mayer, E., Bauman, M., & Landa, R. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0335-3 · Cited by 280 · see citing works
Communication and Symbolic Behavior Scales – Developmental Profile
(2021) · Springer eBooks · doi:10.1007/978-3-319-91280-6_300383 · Cited by 278 · see citing works
(1989) · American Journal of Psychiatry · doi:10.1176/ajp.146.8.1032 · Cited by 255 · see citing works
Screening for autism spectrum disorders in primary care settings
Robins, D. L. (2008) · Autism · doi:10.1177/1362361308094502 · Cited by 239 · see citing works
Personality traits of the relatives of autistic probands
Murphy, M. P., Bolton, P., Pickles, A. R., Fombonne, E. J., Piven, J., & Rutter, M. L. (2000) · Psychological Medicine · doi:10.1017/s0033291799002949 · Cited by 236 · see citing works
Temperament and its relationship to autistic symptoms in a high-risk infant sib cohort
Garon, N., Bryson, S. E., Zwaigenbaum, L., Smith, I. M., Brian, J., Roberts, W., & Szatmari, P. (2009) · Journal of Abnormal Child Psychology · doi:10.1007/s10802-008-9258-0 · Cited by 234 · see citing works
Self-citationClinical assessment of autism in high-risk 18-month-olds
Brian, J., Bryson, S. E., Garon, N., Roberts, W., Smith, I. M., Szatmari, P., & Zwaigenbaum, L. (2008) · Autism · doi:10.1177/1362361308094500 · Cited by 234 · see citing works
Self-citationA prospective study of toddlers with ASD: short‐term diagnostic and cognitive outcomes
Chawarska, K., Klin, A., Paul, R., Macari, S. L., & Volkmar, F. R. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2009.02101.x · Cited by 233 · see citing works
Merin, N. M., Young, G. S., Ozonoff, S. J., & Rogers, S. J. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0342-4 · Cited by 228 · see citing works
Autism Spectrum Disorder Screening and Management Practices Among General Pediatric Providers
dosReis, S., Weiner, C. L., JOHNSON, L., & Newschaffer, C. J. (2006) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200604002-00006 · Cited by 217 · see citing works
The Economic Impact of Autism in Britain
Järbrink, K., & Knapp, M. R. J. (2001) · Autism · doi:10.1177/1362361301005001002 · Cited by 212 · see citing works
Yoder, P. J., Stone, W. L., Walden, T. A., & Malesa, E. E. (2009) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-009-0753-0 · Cited by 211 · see citing works
How early do parent concerns predict later autism diagnosis?
Ozonoff, S., Young, G. S., Steinfeld, M. B., Hill, M. M., Cook, I., Hutman, T., Macari, S., Rogers, S. J., & Sigman, M. (2009) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/dbp.0b013e3181ba0fcf · Cited by 210 · see citing works
Neural correlates of eye gaze processing in the infant broader autism phenotype
Elsabbagh, M., Volein, A., Csibra, G., Holmboe, K., Garwood, H., Tucker, L., Krljes, S., Baron-Cohen, S., Bolton, P., Charman, T., et al. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.09.034 · Cited by 206 · see citing works
Toth, K., Dawson, G., Meltzoff, A. N., Greenson, J., & Fein, D. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0336-2 · Cited by 188 · see citing works
Event Related Potentials in the Understanding of Autism Spectrum Disorders: An Analytical Review
Jeste, S. S., & Nelson, C. A. (2009) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-008-0652-9 · Cited by 179 · see citing works
Loh, A., Soman, T. B., Brian, J. A., Bryson, S. E., Roberts, W., Szatmári, P., Smith, I. M., & Zwaigenbaum, L. (2007) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0333-5 · Cited by 175 · see citing works
Self-citationPandey, J., Verbalis, A. D., Robins, D. L., Boorstein, H., Klin, A., Babitz, T., Chawarska, K., Volkmar, F. R., Green, J., Barton, M. L., et al. (2008) · Autism · doi:10.1177/1362361308094503 · Cited by 163 · see citing works
McCleery, J. P., Akshoomoff, N., Dobkins, K. R., & Carver, L. J. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.07.031 · Cited by 155 · see citing works
Palomo, R., N, M. B., & Ozonoff, S. J. (2006) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200604002-00003 · Cited by 149 · see citing works
Presmanes, A. G., Walden, T. A., Stone, W. L., & Yoder, P. J. (2006) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-006-0338-0 · Cited by 141 · see citing works
Prevalence of Autism among Adolescents with Intellectual Disabilities
Bryson, S. E., Bradley, E. A., Thompson, A., & Wainwright, A. (2008) · The Canadian Journal of Psychiatry · doi:10.1177/070674370805300710 · Cited by 131 · see citing works
System and Cost Research Issues in Treatments for People with Autistic Disorders
Jacobson, J. W., & Mulick, J. A. (2000) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005691411255 · Cited by 130 · see citing works
Stone, W. L., McMahon, C. R., Yoder, P. J., & Walden, T. A. (2007) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpedi.161.4.384 · Cited by 121 · see citing works
Communication and Symbolic Behavior Scales – Developmental Profile
Child Study Center) (2013) · Springer eBooks · doi:10.1007/978-1-4419-1698-3_100339 · Cited by 104 · see citing works
Visual disengagement in the infant siblings of children with an autism spectrum disorder (ASD)
Ibañez, L. V., Messinger, D. S., Newell, L. C., Lambert, B. L., & Sheskin, M. (2008) · Autism · doi:10.1177/1362361308094504 · Cited by 85 · see citing works
Oosterling, I. J., Willemsen‐Swinkels, S. H. N., van der Gaag, R. J., Visser, J. C., Dietz, C., & Buitelaar, J. K. (2009) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-009-0692-9 · Cited by 75 · see citing works
Autism Spectrum Disorders in Young Children
Martínez-Pedraza, F. D. L., & Carter, A. (2009) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2009.02.002 · Cited by 68 · see citing works
Lannon, C., Flower, K. B., Duncan, P., Strazza, K., Stuart, J., & Bassewitz, J. B. (2008) · PEDIATRICS · doi:10.1542/peds.2007-2700 · Cited by 38 · see citing works
Pierce, K., Glatt, S. J., Liptak, G. S., & McIntyre, L. L. (2009) · Annals of Clinical Psychiatry · doi:10.1177/104012370902100302 · Cited by 36 · see citing works
The Role of Nurses in Screening for Autistic Spectrum Disorder in Pediatric Primary Care
Pinto‐Martin, J. A., Souders, M. C., Giarelli, E., & Levy, S. E. (2005) · Journal of Pediatric Nursing · doi:10.1016/j.pedn.2005.01.004 · Cited by 29 · see citing works
The Screening Tool for Autism in Two Year Olds can identify children at risk of autism
Zwaigenbaum, L. (2005) · Evidence-Based Mental Health · doi:10.1136/ebmh.8.3.69 · Cited by 10 · see citing works
Self-citationKuehn, B. M. (2009) · JAMA · doi:10.1001/jama.2009.1049 · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Very early signs of autism reported by parents include many concerns not specific to autism criteria
Guinchat, V., Chamak, B., Bonniau, B., Bodeau, N., Perisse, D., Cohen, D., & Danion, A. (2012) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2011.10.005 · Cited by 162 · see citing works
Social communication difficulties and autism in previously institutionalized children
Levin, A. R., Fox, N. A., Zeanah, C. H., & Nelson, C. A. (2015) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2014.11.011 · Cited by 68 · see citing works
- Authors
- Zwaigenbaum, L.
- Affiliations
- University of Alberta (CA)
- Corresponding author
- Zwaigenbaum, Lonnie
- ORCID
- Zwaigenbaum, Lonnie
- Venue
- Current Opinion in Neurology
- Published
- 2010-04
- Volume
- 23
- Issue
- 2
- Pages
- 97-102
- ISSN
- 1350-7540 (ISSN-L)
- OpenAlex
- W1992542587
- Cited by
- 64
- References
- 60
- Citations by year
- 2023: 1 · 2022: 4 · 2021: 1 · 2020: 5 · 2018: 2 · 2017: 7 · 2016: 2 · 2015: 5 · 2014: 11 · 2013: 11 · 2012: 3
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Current Opinion in Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
- Keywords
- autism spectrum disorder, early detection, early diagnosis, autism screening, high-risk infants, early intervention, toddlers, behavioral expression, neurobiology of autism
- MeSH terms
- Autistic Disorder, Child Development, Humans, Infant, Mass Screening, Early Diagnosis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
