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Perfluorinated compounds affect the function of sex hormone receptors

Kjeldsen, Lisbeth Stigaard, Bonefeld-Jørgensen, Eva Cecilie·2013·Environmental Science and Pollution Research
DOI 10.1007/s11356-013-1753-3
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  1. Andersen HR, Vinggaard AM, Rasmussen TH, Gjermandsen IM, Bonefeld-Jorgensen EC (2002) Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro. Toxicol Appl Pharmacol 179(1):1–12. doi: 10.1006/taap.2001.9347 · DOI · Paper page
  2. Andersen ME, Butenhoff JL, Chang SC, Farrar DG, Kennedy GL Jr, Lau C, Olsen GW, Seed J, Wallace KB (2008) Perfluoroalkyl acids and related chemistries—toxicokinetics and modes of action. Toxicol Sci 102(1):3–14. doi: 10.1093/toxsci/kfm270 · DOI · Paper page
  3. Apelberg BJ, Goldman LR, Calafat AM, Herbstman JB, Kuklenyik Z, Heidler J, Needham LL, Halden RU, Witter FR (2007a) Determinants of fetal exposure to polyfluoroalkyl compounds in Baltimore, Maryland. Environ Sci Technol 41(11):3891–3897 · DOI
  4. Apelberg BJ, Witter FR, Herbstman JB, Calafat AM, Halden RU, Needham LL, Goldman LR (2007b) Cord serum concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in relation to weight and size at birth. Environ Heal Perspect 115(11):1670–1676. doi: 10.1289/ehp.10334 · DOI · Paper page
  5. Benninghoff AD, Bisson WH, Koch DC, Ehresman DJ, Kolluri SK, Williams DE (2011) Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro. Toxicol Sci 120(1):42–58. doi: 10.1093/toxsci/kfq379 · DOI
  6. Biegel LB, Liu RC, Hurtt ME, Cook JC (1995) Effects of ammonium perfluorooctanoate on Leydig cell function: in vitro, in vivo, and ex vivo studies. Toxicol Appl Pharmacol 134(1):18–25. doi: 10.1006/taap.1995.1164 · DOI
  7. Birkhoj M, Nellemann C, Jarfelt K, Jacobsen H, Andersen HR, Dalgaard M, Vinggaard AM (2004) The combined antiandrogenic effects of five commonly used pesticides. Toxicol Appl Pharmacol 201(1):10–20. doi: 10.1016/j.taap.2004.04.016 · DOI
  8. Bjornstrom L, Sjoberg M (2005) Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 19(4):833–842. doi: 10.1210/me.2004-0486 · DOI · Paper page
  9. Bonefeld-Jorgensen EC, Grunfeld HT, Gjermandsen IM (2005) Effect of pesticides on estrogen receptor transactivation in vitro: a comparison of stable transfected MVLN and transient transfected MCF-7 cells. Mol Cell Endocrinol 244(1–2):20–30. doi: 10.1016/j.mce.2005.01.017 · DOI
  10. Bonefeld-Jorgensen EC, Long M, Bossi R, Ayotte P, Asmund G, Kruger T, Ghisari M, Mulvad G, Kern P, Nzulumiki P, Dewailly E (2011) Perfluorinated compounds are related to breast cancer risk in Greenlandic Inuit: a case control study. Env Health 10:88. doi: 10.1186/1476-069X-10-88 · DOI
  11. Bonefeld-Jorgensen EC, Long M, Hofmeister MV, Vinggaard AM (2007) Endocrine-disrupting potential of bisphenol A, bisphenol A dimethacrylate, 4-n-nonylphenol, and 4-n-octylphenol in vitro: new data and a brief review. Environ Heal Perspect 115(Suppl 1):69–76. doi: 10.1289/ehp.9368 · DOI · Paper page
  12. Butenhoff JL, Kennedy GL Jr, Frame SR, O’Connor JC, York RG (2004) The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat. Toxicology 196(1–2):95–116. doi: 10.1016/j.tox.2003.11.005 · DOI · Paper page
  13. Cedergreen N, Christensen AM, Kamper A, Kudsk P, Mathiassen SK, Streibig JC, Sorensen H (2008) A review of independent action compared to concentration addition as reference models for mixtures of compounds with different molecular target sites. Env Toxicol and Chemistry/SETAC 27(7):1621–1632. doi: 10.1897/07-474 · DOI · Paper page
  14. Cook JC, Murray SM, Frame SR, Hurtt ME (1992) Induction of Leydig cell adenomas by ammonium perfluorooctanoate: a possible endocrine-related mechanism. Toxicol Appl Pharmacol 113(2):209–217 · DOI
  15. D’Eon JC, Simpson AJ, Kumar R, Baer AJ, Mabury SA (2010) Determining the molecular interactions of perfluorinated carboxylic acids with human sera and isolated human serum albumin using nuclear magnetic resonance spectroscopy. Env Toxicol and Chem/SETAC 29(8):1678–1688. doi: 10.1002/etc.204 · DOI
  16. Dehm SM, Tindall DJ (2007) Androgen receptor structural and functional elements: role and regulation in prostate cancer. Mol Endocrinol 21(12):2855–2863. doi: 10.1210/me.2007-0223 · DOI · Paper page
  17. Demirpence E, Duchesne MJ, Badia E, Gagne D, Pons M (1993) MVLN cells: a bioluminescent MCE-7-derived cell line to study the modulation of estrogenic activity. The J of Steroid Biochem and Molecular Biol 46(3):355–364 · DOI
  18. DeWitt JC, Peden-Adams MM, Keller JM, Germolec DR (2011) Immunotoxicity of perfluorinated compounds: recent developments. Toxicol Pathol. doi: 10.1177/0192623311428473 · DOI · Paper page
  19. Dreyer C, Krey G, Keller H, Givel F, Helftenbein G, Wahli W (1992) Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors. Cell 68(5):879–887 · DOI · Paper page
  20. Du G, Hu J, Huang H, Qin Y, Han X, Wu D, Song L, Xia Y, Wang X (2012) Perfluorooctane sulfonate (PFOS) affects hormone receptor activity, steroidogenesis, and expression of endocrine-related genes in vitro and in vivo. Env Toxicol and Chem/SETAC. doi: 10.1002/etc.2034 · DOI
  21. Fair PA, Driscoll E, Mollenhauer MA, Bradshaw SG, Yun SH, Kannan K, Bossart GD, Keil DE, Peden-Adams MM (2011) Effects of environmentally-relevant levels of perfluorooctane sulfonate on clinical parameters and immunological functions in B6C3F1 mice. J Immunotoxicol 8(1):17–29. doi: 10.3109/1547691X.2010.527868 · DOI
  22. Fei C, McLaughlin JK, Lipworth L, Olsen J (2008) Prenatal exposure to perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) and maternally reported developmental milestones in infancy. Environ Heal Perspect 116(10):1391–1395. doi: 10.1289/ehp.11277 · DOI
  23. Fei C, McLaughlin JK, Tarone RE, Olsen J (2007) Perfluorinated chemicals and fetal growth: a study within the Danish national birth cohort. Environ Heal Perspect 115(11):1677–1682. doi: 10.1289/ehp.10506 · DOI · Paper page
  24. Fei C, Olsen J (2011) Prenatal exposure to perfluorinated chemicals and behavioral or coordination problems at age 7 years. Environ Heal Perspect 119(4):573–578. doi: 10.1289/ehp.1002026 · DOI
  25. Fromme H, Tittlemier SA, Volkel W, Wilhelm M, Twardella D (2009) Perfluorinated compounds—exposure assessment for the general population in Western countries. Int J Hyg Environ Heal 212(3):239–270. doi: 10.1016/j.ijheh.2008.04.007 · DOI · Paper page
  26. Gao W, Bohl CE, Dalton JT (2005) Chemistry and structural biology of androgen receptor. Chem Rev 105(9):3352–3370. doi: 10.1021/cr020456u · DOI · Paper page
  27. Ghisari M, Bonefeld-Jorgensen EC (2005) Impact of environmental chemicals on the thyroid hormone function in pituitary rat GH3 cells. Mol Cell Endocrinol 244(1–2):31–41. doi: 10.1016/j.mce.2005.01.013 · DOI
  28. Ghisari M, Bonefeld-Jorgensen EC (2009) Effects of plasticizers and their mixtures on estrogen receptor and thyroid hormone functions. Toxicol Lett 189(1):67–77. doi: 10.1016/j.toxlet.2009.05.004 · DOI · Paper page
  29. Giesy JP, Kannan K (2002) Perfluorochemical surfactants in the environment. Environ Sci Technol 36(7):146A–152A · DOI · Paper page
  30. Grandjean P, Andersen EW, Budtz-Jorgensen E, Nielsen F, Molbak K, Weihe P, Heilmann C (2012) Serum vaccine antibody concentrations in children exposed to perfluorinated compounds. JAMA 307(4):391–397. doi: 10.1001/jama.2011.2034 · DOI · Paper page
  31. Grandjean P, Bellinger D, Bergman A, Cordier S, Davey-Smith G, Eskenazi B, Gee D, Gray K, Hanson M, van den Hazel P, Heindel JJ, Heinzow B, Hertz-Picciotto I, Hu H, Huang TT, Jensen TK, Landrigan PJ, McMillen IC, Murata K, Ritz B, Schoeters G, Skakkebaek NE, Skerfving S, Weihe P (2008) The faroes statement: human health effects of developmental exposure to chemicals in our environment. Basic & Clinical Pharmacol & Toxicol 102(2):73–75. doi: 10.1111/j.1742-7843.2007.00114.x · DOI
  32. Haug LS, Huber S, Becher G, Thomsen C (2011) Characterisation of human exposure pathways to perfluorinated compounds—comparing exposure estimates with biomarkers of exposure. Environ Int 37(4):687–693. doi: 10.1016/j.envint.2011.01.011 · DOI · Paper page
  33. Heldring N, Pike A, Andersson S, Matthews J, Cheng G, Hartman J, Tujague M, Strom A, Treuter E, Warner M, Gustafsson JA (2007) Estrogen receptors: how do they signal and what are their targets. Physiol Rev 87(3):905–931. doi: 10.1152/physrev.00026.2006 · DOI · Paper page
  34. Henry ND, Fair PA (2011) Comparison of in vitro cytotoxicity, estrogenicity and anti-estrogenicity of triclosan, perfluorooctane sulfonate and perfluorooctanoic acid. JAT. doi: 10.1002/jat.1736 · DOI
  35. Hoffman K, Webster TF, Weisskopf MG, Weinberg J, Vieira VM (2010) Exposure to polyfluoroalkyl chemicals and attention deficit/hyperactivity disorder in US children 12–15 years of age. Environ Heal Perspect 118(12):1762–1767. doi: 10.1289/ehp.1001898 · DOI · Paper page
  36. Ikeda T, Aiba K, Fukuda K, Tanaka M (1985) The induction of peroxisome proliferation in rat liver by perfluorinated fatty acids, metabolically inert derivatives of fatty acids. J Biochem 98(2):475–482 · DOI
  37. Intrasuksri U, Rangwala SM, O’Brien M, Noonan DJ, Feller DR (1998) Mechanisms of peroxisome proliferation by perfluorooctanoic acid and endogenous fatty acids. Gen Pharmacol 31(2):187–197 · DOI
  38. Ishibashi H, Ishida H, Matsuoka M, Tominaga N, Arizono K (2007) Estrogenic effects of fluorotelomer alcohols for human estrogen receptor isoforms alpha and beta in vitro. Biol Pharm Bull 30(7):1358–1359 · DOI
  39. Johansson N, Eriksson P, Viberg H (2009) Neonatal exposure to PFOS and PFOA in mice results in changes in proteins which are important for neuronal growth and synaptogenesis in the developing brain. Toxicol Sci 108(2):412–418. doi: 10.1093/toxsci/kfp029 · DOI · Paper page
  40. Jones ME, Boon WC, Proietto J, Simpson ER (2006) Of mice and men: the evolving phenotype of aromatase deficiency. TEM 17(2):55–64. doi: 10.1016/j.tem.2006.01.004 · DOI · Paper page
  41. Just WW, Gorgas K, Hartl FU, Heinemann P, Salzer M, Schimassek H (1989) Biochemical effects and zonal heterogeneity of peroxisome proliferation induced by perfluorocarboxylic acids in rat liver. Hepatology 9(4):570–581 · DOI
  42. Keil DE, Mehlmann T, Butterworth L, Peden-Adams MM (2008) Gestational exposure to perfluorooctane sulfonate suppresses immune function in B6C3F1 mice. Toxicol Sci 103(1):77–85. doi: 10.1093/toxsci/kfn015 · DOI
  43. Klaunig JE, Babich MA, Baetcke KP, Cook JC, Corton JC, David RM, DeLuca JG, Lai DY, McKee RH, Peters JM, Roberts RA, Fenner-Crisp PA (2003) PPARalpha agonist-induced rodent tumors: modes of action and human relevance. Crit Rev Toxicol 33(6):655–780. doi: 10.1080/713608372 · DOI · Paper page
  44. Kortenkamp A, Altenburger R (1998) Synergisms with mixtures of xenoestrogens: a reevaluation using the method of isoboles. Sci Total Environ 221(1):59–73 · DOI
  45. Kraugerud M, Zimmer KE, Ropstad E, Verhaegen S (2011) Perfluorinated compounds differentially affect steroidogenesis and viability in the human adrenocortical carcinoma (H295R) in vitro cell assay. Toxicol Lett 205:62–68 · DOI
  46. Kruger T, Long M, Bonefeld-Jorgensen EC (2008) Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor. Toxicology 246(2–3):112–123. doi: 10.1016/j.tox.2007.12.028 · DOI
  47. Kudo N, Iwase Y, Okayachi H, Yamakawa Y, Kawashima Y (2005) Induction of hepatic peroxisome proliferation by 8–2 telomer alcohol feeding in mice: formation of perfluorooctanoic acid in the liver. Toxicol Sci 86(2):231–238. doi: 10.1093/toxsci/kfi191 · DOI
  48. Kudo N, Kawashima Y (2003) Toxicity and toxicokinetics of perfluorooctanoic acid in humans and animals. J Toxicol Sci 28(2):49–57 · DOI · Paper page
  49. Lau C (2012) Perfluorinated compounds. EXS 101:47–86. doi: 10.1007/978-3-7643-8340-4_3 · DOI
  50. Lau C, Butenhoff JL, Rogers JM (2004) The developmental toxicity of perfluoroalkyl acids and their derivatives. Toxicol Appl Pharmacol 198(2):231–241. doi: 10.1016/j.taap.2003.11.031 · DOI · Paper page
  51. Lau C, Thibodeaux JR, Hanson RG, Rogers JM, Grey BE, Stanton ME, Butenhoff JL, Stevenson LA (2003) Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. II: postnatal evaluation. Toxicol Sci 74(2):382–392. doi: 10.1093/toxsci/kfg122 · DOI · Paper page
  52. Lee SS, Pineau T, Drago J, Lee EJ, Owens JW, Kroetz DL, Fernandez-Salguero PM, Westphal H, Gonzalez FJ (1995) Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol Cell Biol 15(6):3012–3022 · DOI · Paper page
  53. Liu C, Du Y, Zhou B (2007) Evaluation of estrogenic activities and mechanism of action of perfluorinated chemicals determined by vitellogenin induction in primary cultured tilapia hepatocytes. Aquat Toxicol 85(4):267–277. doi: 10.1016/j.aquatox.2007.09.009 · DOI
  54. Liu RC, Hurtt ME, Cook JC, Biegel LB (1996) Effect of the peroxisome proliferator, ammonium perfluorooctanoate (C8), on hepatic aromatase activity in adult male Crl: CD BR (CD) rats. Fundam and Appl Toxicol 30(2):220–228 · DOI
  55. Luccio-Camelo DC, Prins GS (2011) Disruption of androgen receptor signaling in males by environmental chemicals. The J of Steroid Biochem and Mol Biol 127(1–2):74–82. doi: 10.1016/j.jsbmb.2011.04.004 · DOI
  56. Luebker DJ, York RG, Hansen KJ, Moore JA, Butenhoff JL (2005) Neonatal mortality from in utero exposure to perfluorooctane sulfonate (PFOS) in Sprague–Dawley rats: dose–response, and biochemical and pharmacokinetic parameters. Toxicology 215(1–2):149–169. doi: 10.1016/j.tox.2005.07.019 · DOI · Paper page
  57. Maestri L, Negri S, Ferrari M, Ghittori S, Fabris F, Danesino P, Imbriani M (2006) Determination of perfluorooctanoic acid and perfluorooctane sulfonate in human tissues by liquid chromatography/single quadrupole mass spectrometry. RCM 20(18):2728–2734. doi: 10.1002/rcm.2661 · DOI
  58. Mueller SO (2004) Xenoestrogens: mechanisms of action and detection methods. Anal Bioanal Chem 378(3):582–587. doi: 10.1007/s00216-003-2238-x · DOI
  59. Needham LL, Grandjean P, Heinzow B, Jorgensen PJ, Nielsen F, Patterson DG Jr, Sjodin A, Turner WE, Weihe P (2011) Partition of environmental chemicals between maternal and fetal blood and tissues. Environ Sci Technol 45(3):1121–1126. doi: 10.1021/es1019614 · DOI · Paper page
  60. Parsons JR, Saez M, Dolfing J, de Voogt P (2008) Biodegradation of perfluorinated compounds. Rev Environ Contam Toxicol 196:53–71 · DOI · Paper page
  61. Payne J, Rajapakse N, Wilkins M, Kortenkamp A (2000) Prediction and assessment of the effects of mixtures of four xenoestrogens. Environ Heal Perspect 108(10):983–987 · DOI
  62. Peden-Adams MM, Keller JM, Eudaly JG, Berger J, Gilkeson GS, Keil DE (2008) Suppression of humoral immunity in mice following exposure to perfluorooctane sulfonate. Toxicol Sci 104(1):144–154. doi: 10.1093/toxsci/kfn059 · DOI · Paper page
  63. Pons M, Gagne D, Nicolas JC, Mehtali M (1990) A new cellular model of response to estrogens: a bioluminescent test to characterize (anti) estrogen molecules. Biotechniques 9(4):450–459
  64. Rajapakse N, Silva E, Kortenkamp A (2002) Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action. Environ Heal Perspect 110(9):917–921 · DOI · Paper page
  65. Rosenmai AK, Nielsen FK, Pedersen M, Hadrup N, Trier X, Christensen JH, Vinggaard AM (2012) Fluorochemicals used in food packaging inhibit male sex hormone synthesis. Toxicol Appl Pharmacol. doi: 10.1016/j.taap.2012.10.022 · DOI
  66. Sikka SC, Wang R (2008) Endocrine disruptors and estrogenic effects on male reproductive axis. Asian J of Andrology 10(1):134–145. doi: 10.1111/j.1745-7262.2008.00370.x · DOI · Paper page
  67. Sohlenius AK, Andersson K, DePierre JW (1992) The effects of perfluoro-octanoic acid on hepatic peroxisome proliferation and related parameters show no sex-related differences in mice. Biochem J 285(Pt 3):779–783 · DOI
  68. Suja F, Pramanik BK, Zain SM (2009) Contamination, bioaccumulation and toxic effects of perfluorinated chemicals (PFCs) in the water environment: a review paper. Water Sci and Techn 60(6):1533–1544. doi: 10.2166/wst.2009.504 · DOI · Paper page
  69. Tao L, Ma J, Kunisue T, Libelo EL, Tanabe S, Kannan K (2008) Perfluorinated compounds in human breast milk from several Asian countries, and in infant formula and dairy milk from the United States. Environ Sci Technol 42(22):8597–8602 · DOI
  70. Tilton SC, Orner GA, Benninghoff AD, Carpenter HM, Hendricks JD, Pereira CB, Williams DE (2008) Genomic profiling reveals an alternate mechanism for hepatic tumor promotion by perfluorooctanoic acid in rainbow trout. Environ Heal Perspect 116(8):1047–1055. doi: 10.1289/ehp.11190 · DOI
  71. Toft G, Jonsson BA, Lindh CH, Giwercman A, Spano M, Heederik D, Lenters V, Vermeulen R, Rylander L, Pedersen HS, Ludwicki JK, Zviezdai V, Bonde JP (2012) Exposure to perfluorinated compounds and human semen quality in Arctic and European populations. Hum Reprod 27(8):2532–2540. doi: 10.1093/humrep/des185 · DOI
  72. Vanden Heuvel JP, Thompson JT, Frame SR, Gillies PJ (2006) Differential activation of nuclear receptors by perfluorinated fatty acid analogs and natural fatty acids: a comparison of human, mouse, and rat peroxisome proliferator-activated receptor-alpha, -beta, and -gamma, liver X receptor-beta, and retinoid X receptor-alpha. Toxicol Sci 92(2):476–489. doi: 10.1093/toxsci/kfl014 · DOI · Paper page
  73. Washino N, Saijo Y, Sasaki S, Kato S, Ban S, Konishi K, Ito R, Nakata A, Iwasaki Y, Saito K, Nakazawa H, Kishi R (2009) Correlations between prenatal exposure to perfluorinated chemicals and reduced fetal growth. Environ Heal Perspect 117(4):660–667. doi: 10.1289/ehp.11681 · DOI · Paper page
  74. Wei Y, Dai J, Liu M, Wang J, Xu M, Zha J, Wang Z (2007) Estrogen-like properties of perfluorooctanoic acid as revealed by expressing hepatic estrogen-responsive genes in rare minnows (Gobiocypris rarus). Env Toxicol and Chem/SETAC 26(11):2440–2447. doi: 10.1897/07-008R1.1 · DOI
  75. Yu WG, Liu W, Jin YH (2009a) Effects of perfluorooctane sulfonate on rat thyroid hormone biosynthesis and metabolism. Env Toxicoland Chem/SETAC 28(5):990–996. doi: 10.1897/08-345.1 · DOI
  76. Yu WG, Liu W, Jin YH, Liu XH, Wang FQ, Liu L, Nakayama SF (2009b) Prenatal and postnatal impact of perfluorooctane sulfonate (PFOS) on rat development: a cross-foster study on chemical burden and thyroid hormone system. Environ Sci Technol 43(21):8416–8422. doi: 10.1021/es901602d · DOI

Cited by

Metadata

Authors
Kjeldsen, L. S., & Bonefeld-Jørgensen, E. C.
Venue
Environmental Science and Pollution Research
Publisher
Springer Science and Business Media LLC
Published
2013-06-14
Volume
20
Issue
11
Pages
8031-8044
ISSN
  • 0944-1344 (ISSN-L)
  • 1614-7499
DOI
10.1007/s11356-013-1753-3
OpenAlex
W2077104587
Cited by
345
References
11
FWCI
16.59
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)

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