The role of adverse childhood experiences in cardiovascular disease risk: a review with emphasis on plausible mechanisms

Su, Shaoyong; Jimenez, Marcia P.; Roberts, Cole T. F.; Loucks, Eric B.

doi:10.1007/s11886-015-0645-1

Cited by 242Child Abuse and TraumaIntimate Partner and Family ViolenceChild Welfare and Adoption

The role of adverse childhood experiences in cardiovascular disease risk: a review with emphasis on plausible mechanisms

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Su, Shaoyong, Jimenez, Marcia P., Roberts, Cole T. F., Loucks, Eric B.·2015·Current Cardiology Reports

DOI 10.1007/s11886-015-0645-1PMC PMC4941633

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Abstract

Childhood adversity, characterized by abuse, neglect, and household dysfunction, is a problem that exerts a significant impact on individuals, families, and society. Growing evidence suggests that adverse childhood experiences (ACEs) are associated with health decline in adulthood, including cardiovascular disease (CVD). In the current review, we first provide an overview of the association between ACEs and CVD risk, with updates on the latest epidemiological evidence. Second, we briefly review plausible pathways by which ACEs could influence CVD risk, including traditional risk factors and novel mechanisms. Finally, we highlight the potential implications of ACEs in clinical and public health. Information gleaned from this review should help physicians and researchers in better understanding potential long-term consequences of ACEs and considering adapting current strategies in treatment or intervention for patients with ACEs.

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Emerging epidemiologic evidence strongly supports that ELS/CT is an independent albeit silent risk factor of future chronic cardiovascular risk through various systemic and molecular mechanisms.
“Emerging epidemiologic evidence strongly supports that ELS/CT is an independent albeit silent risk factor of future chronic cardiovascular risk through various systemic and molecular mechanisms (267–272)”
From Developmental Trajectories of Early Life Stress and Trauma: A Narrative Review on Neurobiological Aspects Beyond Stress System Dysregulation (2019) · cites this paper as [271]
The ‘ACEs and Adult CVD Risk’ section reports associations between childhood adversity and later cardiovascular disease, while ‘Possible Pathways Linking ACEs and CVD Risk’ discusses behavioral and biological mechanisms (pages not provided). But the ‘Conclusion and Future Directions’ section says the findings suggest ACEs *may* affect CVD and calls for stronger studies; it does not establish ACEs as an independent risk factor or the proposed mechanisms as proven. The claim’s ‘strongly supports’ wording overstates the review’s conclusions. (LLM, conf=0.88)
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Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults
Felitti, V. J., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., Koss, M. P., & Marks, J. S. (1998) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(98)00017-8 · Cited by 18,943 · see citing works
Child abuse: Adolescent records vs. adult recall
Femina, D. D., Yeager, C. A., & Lewis, D. O. (1990) · Child Abuse & Neglect · doi:10.1016/0145-2134(90)90033-p · Cited by 8,820 · see citing works
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
Lang, U. E., & Borgwardt, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350094 · Cited by 8,501 · see citing works
Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., de Ferranti, S., Després, J.-P., Fullerton, H. J., Howard, V. J., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000152 · Cited by 5,797 · see citing works
In silico analysis enabling informed design for genome editing in medicinal cannabis; gene families and variant characterisation
Calamita, E., Schmid, M., Kunz, M., Ndebele-Murisa, M. R., Magadza, C. H. D., Nyambe, I., & Wehrli, B. (2019) · Figshare · doi:10.26181/6153922fe919c · Cited by 4,222 · see citing works
Association between Multiple Cardiovascular Risk Factors and Atherosclerosis in Children and Young Adults
Berenson, G. S., Srinivasan, S. R., Bao, W., Newman, W. P., Tracy, R. E., & Wattigney, W. A. (1998) · New England Journal of Medicine · doi:10.1056/nejm199806043382302 · Cited by 4,032 · see citing works
Risky families: Family social environments and the mental and physical health of offspring
Repetti, R. L., Taylor, S. E., & Seeman, T. E. (2002) · Psychological Bulletin · doi:10.1037/0033-2909.128.2.330 · Cited by 2,884 · see citing works
Physical activity and mental health in children and adolescents: a review of reviews
Biddle, S. J. H., & Asare, M. (2011) · British Journal of Sports Medicine · doi:10.1136/bjsports-2011-090185 · Cited by 2,447 · see citing works
Adverse childhood experiences and the risk of depressive disorders in adulthood
Chapman, D. P., Whitfield, C. L., Felitti, V. J., Dube, S. R., Edwards, V. J., & Anda, R. F. (2004) · Journal of Affective Disorders · doi:10.1016/j.jad.2003.12.013 · Cited by 2,267 · see citing works
Adverse childhood experiences, allostasis, allostatic load and age-related disease
Danese, A., & McEwen, B. S. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.08.019 · Cited by 2,140 · see citing works
Variations in the Prevalence of Obesity Among European Countries, and a Consideration of Possible Causes
Blundell, J. E., Baker, J. L., Boyland, E. J., Blaak, E. E., Charzewska, J., Henauw, S. D., Frühbeck, G., González‐Gross, M., Hebebrand, J., Holm, L., et al. (2017) · Obesity Facts · doi:10.1159/000455952 · Cited by 1,980 · see citing works
Psychological stress in childhood and susceptibility to the chronic diseases of aging: Moving toward a model of behavioral and biological mechanisms.
Miller, G. E., Chen, E., & Parker, K. J. (2011) · Psychological Bulletin · doi:10.1037/a0024768 · Cited by 1,785 · see citing works
The interrelatedness of multiple forms of childhood abuse, neglect, and household dysfunction
Dong, M., Anda, R. F., Felitti, V. J., Dube, S. R., Williamson, D. F., Thompson, T. J., Loo, C. M., & Giles, W. H. (2004) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2004.01.008 · Cited by 1,679 · see citing works
Traumatic Events and Posttraumatic Stress in Childhood
Copeland, W., Keeler, G. P., Angold, A. C., & Costello, E. J. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.5.577 · Cited by 1,547 · see citing works
Depression and Coronary Heart Disease: Recommendations for Screening, Referral, and Treatment: A Science Advisory From the American Heart Association Prevention Committee of the Council on Cardiovascular Nursing, Council on Clinical Cardiology, Council on Epidemiology and Prevention, and Interdisciplinary Council on Quality of Care and Outcomes Research: <i>Endorsed by the American Psychiatric Association</i>
Lichtman, J. H., Bigger, J. T., Blumenthal, J. A., Frasure-Smith, N., Kaufmann, P. G., Lespérance, F., Mark, D. B., Sheps, D. S., Taylor, C. B., & Froelicher, E. S. (2008) · Circulation · doi:10.1161/circulationaha.108.190769 · Cited by 1,482 · see citing works
The Bogalusa Heart Study
Allhoff, P., Laaser, U., & Heinrich, J. (1991) · Springer eBooks · doi:10.1007/978-3-642-95642-3_7 · Cited by 1,331 · see citing works
Stress and cardiovascular disease
Steptoe, A., & Kivimäki, M. (2012) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2012.45 · Cited by 1,321 · see citing works
Trends over 5 Decades in U.S. Occupation-Related Physical Activity and Their Associations with Obesity
Church, T. S., Thomas, D. M., Tudor-Locke, C., Katzmarzyk, P. T., Earnest, C. P., Rodarte, R. Q., Martin, C. K., Blair, S. N., & Bouchard, C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019657 · Cited by 1,294 · see citing works
Adverse Childhood Experiences and Smoking During Adolescence and Adulthood
Anda, R. F. (1999) · JAMA · doi:10.1001/jama.282.17.1652 · Cited by 1,256 · see citing works
Adverse Childhood Experiences and Adult Risk Factors for Age-Related Disease: Depression, Inflammation, and Clustering of Metabolic Risk Markers
Danese, A., Moffitt, T. E., Harrington, H., Milne, B. J., Polanczyk, G., Pariante, C. M., Poulton, R., & Caspi, A. (2009) · Archives of Pediatrics & Adolescent Medicine · doi:10.1001/archpediatrics.2009.214 · Cited by 1,165 · see citing works
Early Childhood Investments Substantially Boost Adult Health
Campbell, F., Conti, G., Heckman, J. J., Moon, S. H., Pinto, R., Pungello, E., & Pan, Y. (2014) · Science · doi:10.1126/science.1248429 · Cited by 1,106 · see citing works
Early Childhood Adversity, Toxic Stress, and the Role of the Pediatrician: Translating Developmental Science Into Lifelong Health
Garner, A. S., Shonkoff, J. P., Siegel, B., Dobbins, M. I., Earls, M. F., Garner, A. S., McGuinn, L. J., Pascoe, J. M., & Wood, D. L. (2011) · PEDIATRICS · doi:10.1542/peds.2011-2662 · Cited by 1,039 · see citing works
The impact of adverse childhood experiences on health problems: evidence from four birth cohorts dating back to 1900
Dube, S. R., Felitti, V. J., Dong, M., Giles, W. H., & Anda, R. F. (2003) · Preventive Medicine · doi:10.1016/s0091-7435(03)00123-3 · Cited by 1,034 · see citing works
Insights Into Causal Pathways for Ischemic Heart Disease: Adverse Childhood Experiences Study
Dong, M., Giles, W. H., Felitti, V. J., Dube, S. R., Williams, J. E., Chapman, D. P., & Anda, R. F. (2004) · Circulation · doi:10.1161/01.cir.0000143074.54995.7f · Cited by 1,027 · see citing works
Long-term physical and mental health consequences of childhood physical abuse: results from a large population-based sample of men and women
Springer, K. W., Sheridan, J., Kuo, D., & Carnes, M. (2007) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2007.01.003 · Cited by 964 · see citing works
A LIFE COURSE APPROACH TO CHRONIC DISEASE EPIDEMIOLOGY
Lynch, J. W., & Smith, G. D. (2005) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.26.021304.144505 · Cited by 923 · see citing works
The Biological Effects of Childhood Trauma
De Bellis, M. D., & Zisk, A. (2014) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2014.01.002 · Cited by 892 · see citing works
Violence, Crime, and Abuse Exposure in a National Sample of Children and Youth
David Finkelhor, B., Turner, H. A., Shattuck, A., & Hamby, S. L. (2013) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2013.42 · Cited by 781 · see citing works
The long-term sequelae of child and adolescent abuse: a longitudinal community study
Silverman, A. B., Reinherz, H. Z., & Giaconia, R. M. (1996) · Child Abuse & Neglect · doi:10.1016/0145-2134(96)00059-2 · Cited by 730 · see citing works
Childhood maltreatment and obesity: systematic review and meta-analysis
Danese, A., & Tan, M. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.54 · Cited by 709 · see citing works
Childhood maltreatment, emotional dysregulation, and psychiatric comorbidities
Dvir, Y., Ford, J. D., Hill, M., & Frazier, J. A. (2014) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000014 · Cited by 698 · see citing works
Early-Life Adversity and Physical and Emotional Health Across the Lifespan: A Neuroimmune Network Hypothesis
Nusslock, R., & Miller, G. E. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.05.017 · Cited by 672 · see citing works
Neuroimaging of child abuse: a critical review
Hart, H., & Rubia, K. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00052 · Cited by 660 · see citing works
Childhood Adversity and Adult Chronic Disease
Gilbert, L. K., Breiding, M. J., Merrick, M. T., Thompson, W., Ford, D. C., Dhingra, S. S., & Parks, S. E. (2014) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2014.09.006 · Cited by 615 · see citing works
Adverse Childhood Experiences
Asmundson, G. J. G., & Afifi, T. O. (2020) · Elsevier eBooks · doi:10.1016/c2017-0-03827-2 · Cited by 580 · see citing works
Effectiveness and cost-effectiveness of mindfulness-based cognitive therapy compared with maintenance antidepressant treatment in the prevention of depressive relapse or recurrence (PREVENT): a randomised controlled trial
Kuyken, W., Hayes, R., Barrett, B., Byng, R., Dalgleish, T., Kessler, D., Lewis, G., Watkins, E., Brejcha, C., Cardy, J., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(14)62222-4 · Cited by 527 · see citing works
Adverse childhood experiences: retrospective study to determine their impact on adult health behaviours and health outcomes in a UK population
Bellis, M. A., Lowey, H., Leckenby, N., Hughes, K., & Harrison, D. (2014) · Journal of Public Health · doi:10.1093/pubmed/fdt038 · Cited by 525 · see citing works
Depression Screening and Patient Outcomes in Cardiovascular Care: A Systematic Review
Thombs, B. D., de Jonge, P., Coyne, J. C., Whooley, M. A., Frasure-Smith, N., Mitchell, A. J., Zuidersma, M., Eze-Nliam, C., Lima, B. B., Smith, C. G., et al. (2008) · JAMA · doi:10.1001/jama.2008.667 · Cited by 472 · see citing works
Heartache and heartbreak—the link between depression and cardiovascular disease
Nemeroff, C. B., & Goldschmidt-Clermont, P. J. (2012) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2012.91 · Cited by 424 · see citing works
Trauma Informed Care in Medicine
Raja, S., Hasnain, M., Hoersch, M., Gove-Yin, S., & Rajagopalan, C. F. (2015) · Family & Community Health · doi:10.1097/fch.0000000000000071 · Cited by 421 · see citing works
Preventing Tobacco use Among Young People
Schinke, S. P., & Gilchrist, L. D. (1986) · Health & Social Work · doi:10.1093/hsw/11.1.59 · Cited by 401 · see citing works
Adverse childhood experiences are associated with adult sleep disorders: a systematic review
Kajeepeta, S., Gelaye, B., Jackson, C. L., & Williams, M. A. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2014.12.013 · Cited by 385 · see citing works
WOMEN AND MEN
Scheinfeld, A. (1945) · The American Journal of the Medical Sciences · doi:10.1097/00000441-194507000-00025 · Cited by 381 · see citing works
Adverse childhood experiences and associations with health-harming behaviours in young adults: surveys in eight eastern European countries
Bellis, M. A., Hughes, K., Leckenby, N., Jones, L., Baban, A., Kachaeva, M., Povilaitis, R., Pudule, I., Qirjako, G., Ulukol, B., et al. (2014) · Bulletin of the World Health Organization · doi:10.2471/blt.13.129247 · Cited by 338 · see citing works
Obesity and Type 2 Diabetes Risk in Midadult Life: The Role of Childhood Adversity
Thomas, C., Hyppönen, E., & Power, C. (2008) · Pediatrics · doi:10.1542/peds.2007-2403 · Cited by 330 · see citing works
Psychological interventions for coronary heart disease: Cochrane systematic review and meta-analysis
Richards, S. H., Anderson, L., Jenkinson, C. E., Whalley, B., Rees, K., Davies, P., Bennett, P., Liu, Z., West, R., Thompson, D. R., et al. (2018) · European Journal of Preventive Cardiology · doi:10.1177/2047487317739978 · Cited by 319 · see citing works
Sleep Quality and Elevated Blood Pressure in Adolescents
Javaheri, S., Storfer‐Isser, A., ROSEN, C. L., & Redline, S. S. (2008) · Circulation · doi:10.1161/circulationaha.108.766410 · Cited by 310 · see citing works
Biological embedding of stress through inflammation processes in childhood
Danese, A., Caspi, A., Williams, B., Ambler, A., Sugden, K., Mika, J., Werts, H., Freeman, J., Pariante, C. M., Moffitt, T. E., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.5 · Cited by 301 · see citing works
The theory of latent vulnerability: reconceptualizing the link between childhood maltreatment and psychiatric disorder
McCrory, E. J., & Viding, E. (2015) · Development and Psychopathology · doi:10.1017/s0954579415000115 · Cited by 295 · see citing works
A systematic review of the emotional, behavioural and cognitive features exhibited by school‐aged children experiencing neglect or emotional abuse
Maguire, S., Williams, B. T., Naughton, A., Cowley, L., Tempest, V., Mann, M. K., Teague, M., & Kemp, A. (2015) · Child Care Health and Development · doi:10.1111/cch.12227 · Cited by 275 · see citing works
The role of childhood abuse and neglect in the sensitization to stressful life events in adolescent depression
Harkness, K. L., Bruce, A. E., & Lumley, M. N. (2006) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.115.4.730 · Cited by 272 · see citing works
A Review of Evidence for the Link Between Sleep Duration and Hypertension
Gangwisch, J. E. (2014) · American Journal of Hypertension · doi:10.1093/ajh/hpu071 · Cited by 261 · see citing works
Post-traumatic Stress Disorder, Coronary Atherosclerosis, and Mortality
Ahmadi, N., Hajsadeghi, F., Mirshkarlo, H. B., Budoff, M., Yehuda, R., & Ebrahimi, R. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.02.340 · Cited by 257 · see citing works
Adverse childhood experiences and smoking status in five states
Ford, E. S., Anda, R. F., Edwards, V. J., Perry, G. S., Zhao, G., Li, C., & Croft, J. B. (2011) · Preventive Medicine · doi:10.1016/j.ypmed.2011.06.015 · Cited by 254 · see citing works
Post-Traumatic Stress Disorder and Incidence of Coronary Heart Disease
Vaccarino, V., Goldberg, J., Rooks, C., Shah, A. J., Veledar, E., Faber, T. L., Votaw, J. R., Forsberg, C. W., & Bremner, J. D. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.04.085 · Cited by 247 · see citing works
Childhood Residential Mobility and Multiple Health Risks During Adolescence and Adulthood
Dong, M., Anda, R. F., Felitti, V. J., Williamson, D. F., Dube, S. R., Brown, D. W., & Giles, W. H. (2005) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.159.12.1104 · Cited by 234 · see citing works
Adverse Childhood Experiences and Blood Pressure Trajectories From Childhood to Young Adulthood
Su, S., Wang, X., Pollock, J. S., Treiber, F. A., Xu, X., Snieder, H., McCall, W. V., Stefanek, M. E., & Harshfield, G. A. (2015) · Circulation · doi:10.1161/circulationaha.114.013104 · Cited by 226 · see citing works
Self-citation
The role of child sexual abuse in the etiology of suicide and non-suicidal self-injury
Maniglio, R. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2010.01612.x · Cited by 225 · see citing works
Endothelin—Biology and disease
Khimji, A.-K., & Rockey, D. C. (2010) · Cellular Signalling · doi:10.1016/j.cellsig.2010.05.002 · Cited by 222 · see citing works
Abuse in Childhood and Adolescence As a Predictor of Type 2 Diabetes in Adult Women
Rich-Edwards, J. W., Spiegelman, D. L., Hibert, E. N. L., Jun, H., Todd, T. J., Kawachi, I. I., & Wright, R. J. (2010) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2010.09.007 · Cited by 222 · see citing works
Post-traumatic Stress Disorder and Cardiovascular Disease
Coughlin, S. S. (2011) · The Open Cardiovascular Medicine Journal · doi:10.2174/1874192401105010164 · Cited by 216 · see citing works
Physical and Sexual Abuse in Childhood as Predictors of Early-Onset Cardiovascular Events in Women
Rich-Edwards, J. W., Mason, S. M., Rexrode, K. M., Spiegelman, D. L., Hibert, E. N. L., Kawachi, I. I., Jun, H. J., & Wright, R. J. (2012) · Circulation · doi:10.1161/circulationaha.111.076877 · Cited by 215 · see citing works
[Solitary median maxillary central incisor syndrome:a case of report].
Kang, L.-Y., & Liu, X. (2014) · PubMed · Cited by 208 · see citing works
Predictive Validity in a Prospective Follow-up of PTSD in Preschool Children
Scheeringa, M. S., Zeanah, C. H., Myers, L., & Putnam, F. W. (2005) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000169013.81536.71 · Cited by 200 · see citing works
Better Population Health Through Behavior Change in Adults: A Call to Action
Spring, B., Ockene, J. K., Gidding, S. S., Mozaffarian, D., Moore, S., Rosal, M. C., Brown, M. D., Vafiadis, D. K., Cohen, D. L., Burke, L. E., et al. (2013) · Circulation · doi:10.1161/01.cir.0000435173.25936.e1 · Cited by 195 · see citing works
Associations of child sexual and physical abuse with obesity and depression in middle-aged women
Rohde, P., Ichikawa, L., Simon, G. E., Ludman, E. J., Linde, J. A., Jeffery, R. W., & Operskalski, B. H. (2008) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2007.11.004 · Cited by 189 · see citing works
The traumatic stress response in child maltreatment and resultant neuropsychological effects
Wilson, K. R., Hansen, D. J., & Li, M. (2011) · Aggression and Violent Behavior · doi:10.1016/j.avb.2010.12.007 · Cited by 175 · see citing works
Posttraumatic Stress Disorder in Maltreated Youth: A Review of Contemporary Research and Thought
Kearney, C. A., Wechsler, A., Kaur, H., & Lemos-Miller, A. (2010) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-009-0061-4 · Cited by 169 · see citing works
Interpersonal violence in childhood as a risk factor for obesity: a systematic review of the literature and proposed pathways
Midei, A. J., & Matthews, K. A. (2011) · Obesity Reviews · doi:10.1111/j.1467-789x.2010.00823.x · Cited by 167 · see citing works
Health Risk Behaviors and Mental Health Problems as Mediators of the Relationship Between Childhood Abuse and Adult Health
Chartier, M., Walker, J. R., & Naimark, B. J. (2009) · American Journal of Public Health · doi:10.2105/ajph.2007.122408 · Cited by 167 · see citing works
Adverse childhood experiences and frequent insufficient sleep in 5 U.S. States, 2009: a retrospective cohort study
Chapman, D. P., Liu, Y., Presley-Cantrell, L. R., Edwards, V. J., Wheaton, A. G., Perry, G. S., & Croft, J. B. (2013) · BMC Public Health · doi:10.1186/1471-2458-13-3 · Cited by 159 · see citing works
Endothelin-1 induces interleukin-6 release via acctivation of the transcription factor NF-κB in human vascular smooth muscle cells
Browatzki, M., Schmidt, J., Kübler, W., & Kranzhöfer, R. (2000) · Basic Research in Cardiology · doi:10.1007/s003950050170 · Cited by 157 · see citing works
A Review on the Genetic, Environmental, and Lifestyle Aspects of the Early-Life Origins of Cardiovascular Disease
Kelishadi, R., & Poursafa, P. (2014) · Current problems in pediatric and adolescent health care · doi:10.1016/j.cppeds.2013.12.005 · Cited by 155 · see citing works
Violence from parents in childhood and obesity in adulthood: Using food in response to stress as a mediator of risk
Greenfield, E. A., & Marks, N. F. (2009) · Social Science & Medicine · doi:10.1016/j.socscimed.2008.12.004 · Cited by 150 · see citing works
Psychological interventions for coronary heart disease: Cochrane systematic review and meta-analysis
Whalley, B., Thompson, D. R., & Taylor, R. S. (2014) · International Journal of Behavioral Medicine · doi:10.1007/s12529-012-9282-x · Cited by 149 · see citing works
Emotional, Behavioral, and Developmental Features Indicative of Neglect or Emotional Abuse in Preschool Children
Naughton, A., Maguire, S., Mann, M. K., Lumb, R. C., Tempest, V., Gracias, S., & Kemp, A. (2013) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2013.192 · Cited by 136 · see citing works
Girls’ Perception of Neighborhood Factors on Physical Activity, Sedentary Behavior, and BMI
Evenson, K. R., Scott, M., Cohen, D. A., & Voorhees, C. C. (2007) · Obesity · doi:10.1038/oby.2007.502 · Cited by 135 · see citing works
Adverse Childhood Experiences and Smoking Persistence in Adults with Smoking-Related Symptoms and Illness
Edwards, V. J., Anda, R. F., Gu, D., Dube, S. R., & Felitti, V. J. (2007) · The Permanente Journal · doi:10.7812/tpp/06-110 · Cited by 133 · see citing works
Fetal Programming of Brain Development: Intrauterine Stress and Susceptibility to PsychopathologyA Presentation from the European Society for Paediatric Endocrinology (ESPE) New Inroads to Child Health (NICHe) Conference on Stress Response and Child Health in Heraklion, Crete, Greece, 18 to 20 May 2012.
Buß, C., Entringer, S., & Wadhwa, P. D. (2012) · Science Signaling · doi:10.1126/scisignal.2003406 · Cited by 131 · see citing works
Post-Traumatic Stress Disorder
Wentworth, B. A., Stein, M. B., Redwine, L. S., Xue, Y., Taub, P. R., Clopton, P., Nayak, K. R., & Maisel, A. S. (2012) · Cardiology in Review · doi:10.1097/crd.0b013e318265343b · Cited by 130 · see citing works
Hypertension in adult survivors of child abuse: observations from the Nurses' Health Study II
Riley, E. H., Wright, R. J., Jun, H. J., Hibert, E. N., & Rich-Edwards, J. W. (2010) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2009.095109 · Cited by 124 · see citing works
Childhood adversities as predictors of incident coronary heart disease and cerebrovascular disease
Korkeila, J., Vahtera, J., Korkeila, K., Kivimäki, M., Sumanen, M., Koskenvuo, K., & Koskenvuo, M. (2010) · Heart · doi:10.1136/hrt.2009.188250 · Cited by 124 · see citing works
Effect of Collaborative Care for Depression on Risk of Cardiovascular Events
Stewart, J. C., Perkins, A. J., & Callahan, C. M. (2013) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000022 · Cited by 121 · see citing works
Contrasting Inotropic Effects of Endogenous Endothelin in the Normal and Failing Human Heart
MacCarthy, P. A., Grocott-Mason, R. M., Prendergast, B., & Shah, A. M. (2000) · Circulation · doi:10.1161/01.cir.101.2.142 · Cited by 119 · see citing works
Early Childhood Adversity and Later Hypertension: Data from the World Mental Health Survey
Stein, D. J., Scott, K., Haro Abad, J. M., Aguilar-Gaxiola, S., Alonso, J., Angermeyer, M., Demytteneare, K., de Girolamo, G., Iwata, N., Posada-Villa, J., et al. (2010) · Annals of Clinical Psychiatry · doi:10.1177/104012371002200104 · Cited by 118 · see citing works
The Relationship Between Child Abuse and Adult Obesity Among California Women
Alvarez, J., Pavao, J., Baumrind, N., & Kimerling, R. E. (2007) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2007.02.036 · Cited by 117 · see citing works
Creating a Healthier Future Through Early Interventions for Children
Mercy, J. A. (2009) · JAMA · doi:10.1001/jama.2009.803 · Cited by 116 · see citing works
Role of endothelin in the cardiovascular system
Rodríguez‐Pascual, F., Busnadiego, Ó., Lagares, D., & Lamas, S. (2011) · Pharmacological Research · doi:10.1016/j.phrs.2011.01.014 · Cited by 112 · see citing works
Behavioural consequences of child abuse.
Odhayani, A. A., Watson, W. J., & Watson, L. (2013) · Europe PMC (PubMed Central) · Cited by 112 · see citing works
Epidemiology of Sleep Disturbances and Cardiovascular Consequences.
Badran, M., Yassin, B. A., Fox, N., Laher, I., & Ayas, N. (2015) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2015.03.011 · Cited by 109 · see citing works
Adverse Events in Children
Niel, C. W. V., Pachter, L. M., Wade, R., Felitti, V. J., & Stein, M. T. (2014) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/dbp.0000000000000102 · Cited by 100 · see citing works
Adverse Childhood Experiences Are Associated With Detrimental Hemodynamics and Elevated Circulating Endothelin-1 in Adolescents and Young Adults
Su, S., Wang, X., Kapuku, G. K., Treiber, F. A., Pollock, D. M., Harshfield, G. A., McCall, W. V., & Pollock, J. S. (2014) · Hypertension · doi:10.1161/hypertensionaha.113.02755 · Cited by 98 · see citing works
Self-citation
Retrospective and prospectively assessed childhood adversity in association with major depression, alcohol consumption and painful conditions
Patten, S. B., Wilkes, T. C. R., Williams, J. V. A., Lavorato, D. H., el-Guebaly, N., Schopflocher, D., Wild, C., Colman, I., & Bulloch, A. G. M. (2015) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796014000018 · Cited by 95 · see citing works
Psychiatry
(2008) · Wiley eBooks · doi:10.1002/9780470515167 · Cited by 84 · see citing works
Health-related outcomes of adverse childhood experiences in Texas, 2002.
(2010) · PubMed Central · Cited by 79 · see citing works
Childhood Sexual Abuse and Its Association With Adult Physical and Mental Health
Coles, J. Y., Lee, A., Taft, A., Mazza, D., & Loxton, D. J. (2014) · Journal of Interpersonal Violence · doi:10.1177/0886260514555270 · Cited by 78 · see citing works
The enduring effects of early-childhood adversities and troubled sleep among Canadian adults: a population-based study
Baiden, P., Fallon, B., den Dunnen, W., & Boateng, G. O. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2015.02.527 · Cited by 77 · see citing works
Childhood abuse is associated with adiposity in midlife women: possible pathways through trait anger and reproductive hormones
Midei, A. J., Matthews, K. A., & Bromberger, J. T. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181cb5c24 · Cited by 72 · see citing works
Gender-specific association between childhood adversities and smoking in adulthood: findings from a population-based study
Fuller-Thomson, E., Filippelli, J., & Lue-Crisostomo, C. A. (2013) · Public Health · doi:10.1016/j.puhe.2013.01.006 · Cited by 71 · see citing works
Childhood family psychosocial environment and carotid intima media thickness: The CARDIA study
Loucks, E. B., Taylor, S. E., Polak, J. F., Wilhelm, A., Kalra, P., & Matthews, K. A. (2013) · Social Science & Medicine · doi:10.1016/j.socscimed.2013.12.015 · Cited by 70 · see citing works
Self-citation
Abuse and Subclinical Cardiovascular Disease Among Midlife Women
Thurston, R. C., Chang, Y., Derby, C. A., Bromberger, J. T., Harlow, S. D., Janssen, İ., & Matthews, K. A. (2014) · Stroke · doi:10.1161/strokeaha.114.005928 · Cited by 68 · see citing works
Life Course Epidemiology of Trauma and Related Psychopathology in Civilian Populations
Fink, D. S., & Galea, S. (2015) · Current Psychiatry Reports · doi:10.1007/s11920-015-0566-0 · Cited by 68 · see citing works
Childhood Family Psychosocial Environment and Coronary Heart Disease Risk
Loucks, E. B., Almeida, N., Taylor, S. E., & Matthews, K. A. (2011) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318228c820 · Cited by 62 · see citing works
Self-citation
The mediating sex-specific effect of psychological distress on the relationship between adverse childhood experiences and current smoking among adults
Strine, T. W., Edwards, V. J., Dube, S. R., Wagenfeld, M. O., Dhingra, S. S., Prehn, A. W., Rasmussen, S., McKnight-Eily, L. R., & Croft, J. B. (2012) · Substance Abuse Treatment Prevention and Policy · doi:10.1186/1747-597x-7-30 · Cited by 61 · see citing works
Does childhood misfortune raise the risk of acute myocardial infarction in adulthood?
Morton, P. M., Mustillo, S., & Ferraro, K. F. (2013) · Social Science & Medicine · doi:10.1016/j.socscimed.2013.11.026 · Cited by 60 · see citing works
Childhood adversity and asthma prevalence: evidence from 10 US states (2009–2011)
Bhan, N., Glymour, M., Kawachi, I., & Subramanian, S. (2014) · BMJ Open Respiratory Research · doi:10.1136/bmjresp-2013-000016 · Cited by 54 · see citing works
Early life stress downregulates endothelin receptor expression and enhances acute stress-mediated blood pressure responses in adult rats
Loria, A. S., D’Angelo, G., Pollock, D. M., & Pollock, J. S. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00333.2009 · Cited by 41 · see citing works
Obesity: Problem, Solution, or Both?
Felitti, V. J., Jakstis, K., Pepper, V., & Ray, A. (2010) · The Permanente Journal · doi:10.7812/tpp/10.996 · Cited by 39 · see citing works
Relationship Between Abuse and Neglect in Childhood and Diabetes in Adulthood: Differential Effects By Sex, National Longitudinal Study of Adolescent Health
Duncan, A. E., Auslander, W., Bucholz, K. K., Hudson, D., Stein, R. I., & White, N. H. (2015) · Preventing Chronic Disease · doi:10.5888/pcd12.140434 · Cited by 38 · see citing works
PTSD is a risk factor for cardiovascular disease: Time for increased screening and clinical intervention
Boscarino, J. A. (2012) · Preventive Medicine · doi:10.1016/j.ypmed.2012.01.001 · Cited by 35 · see citing works
Quality of Parental Emotional Care and Calculated Risk for Coronary Heart Disease
Almeida, N., Loucks, E. B., Kubzansky, L. D., Pruessner, J. C., Maselko, J., Meaney, M. J., & Buka, S. L. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181c925cb · Cited by 29 · see citing works
Self-citation
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Onose, T., Nochioka, K., Sakata, Y., Miura, M., Tadaki, S., Ushigome, R., Yamauchi, T., Sato, K., Tsuji, K., Abe, R., et al. (2015) · Circulation Journal · doi:10.1253/circj.cj-14-1403 · Cited by 27 · see citing works
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Felitti, V. J., & Williams, S. (1998) · The Permanente Journal · doi:10.7812/tpp/98.932 · Cited by 26 · see citing works
The relationship between childhood physical and emotional abuse and smoking cessation among U.S. women and men.
Smith, P. H., Saddleson, M. L., Homish, G. G., McKee, S. A., Kozlowski, L. T., & Giovino, G. A. (2014) · Psychology of Addictive Behaviors · doi:10.1037/adb0000033 · Cited by 24 · see citing works
Childhood Adversity as a Predictor of Non-Adherence to Statin Therapy in Adulthood
Korhonen, M. J., Halonen, J. I., Brookhart, M. A., Kawachi, I. I., Pentti, J., Karlsson, H., Mika Kivimaki, B., & Vahtera, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127638 · Cited by 22 · see citing works
Childhood adversity and subsequent mental health status in adulthood: screening for associations using two linked surveys
Patten, S. B., Wilkes, T. C., Williams, J. V. A., Lavorato, D. H., el‐Guebaly, N., Wild, T. C., Colman, I., & Bulloch, A. G. M. (2015) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796015000104 · Cited by 21 · see citing works
Obesity: Problem, Solution, or Both?
Felitti, V. J. (2010) · The Permanente Journal · doi:10.7812/tpp/09-107 · Cited by 20 · see citing works
Posttraumatic Stress and Myocardial Infarction Risk Perceptions in Hospitalized Acute Coronary Syndrome Patients
Edmondson, D. E., Shaffer, J. A., Denton, E.-G. D., Shimbo, D., & Clemow, L. (2012) · Frontiers in Psychology · doi:10.3389/fpsyg.2012.00144 · Cited by 14 · see citing works
Does social disadvantage over the life-course account for alcohol and tobacco use in Irish people? Birth cohort study
Das‐Munshi, J., Leavey, G., Stansfeld, S. A., & Prince, M. J. (2013) · European Journal of Public Health · doi:10.1093/eurpub/ckt122 · Cited by 7 · see citing works

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[105]Tasman AKJ Lieberman JA First MB Maj M Psychiatry 2008 Wiley Hoboken
[110]Center for Substance Abuse Treatment (US) Trauma-Informed Care in Behavioral Health Services 2014 Substance Abuse and Mental Health Services Administration (US Rockville (MD) (Treatment Improvement Protocol (TIP) Series, No. 57.) Available from: http://www.ncbi.nlm.nih.gov/books/NBK207201/ 24901203

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Hazlehurst, M. F., Nurius, P. S., & Hajat, A. (2018) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph15030472 · Cited by 35 · see citing works
Adverse childhood and adulthood experiences and risk of new-onset cardiovascular disease with consideration of social support: a prospective cohort study
Wang, W.-X., Liu, Y.-F., Yang, Y.-W., Jiang, W.-Q., Ni, Y.-Y., Han, X., Lu, C.-Y., & Guo, L. (2023) · BMC Medicine · doi:10.1186/s12916-023-03015-1 · Cited by 28 · see citing works
Is parental unemployment associated with increased risk of adverse childhood experiences? A systematic review and meta-analysis
Judd, N., Hughes, K. E., Bellis, M. A., Hardcastle, K., & Amos, R. (2023) · Journal of Public Health · doi:10.1093/pubmed/fdad069 · Cited by 35 · see citing works
Childhood adversity and accelerated reproductive events: a systematic review and meta-analysis
Ding, W.-Q., Yuxiang, X., Kondracki, A. J., & Sun, Y. (2023) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2023.10.005 · Cited by 36 · see citing works
Cardiovascular Health at the Intersection of Race and Gender: Identifying Life-Course Processes to Reduce Health Disparities
Lee, C., Park, S., & Boylan, J. M. (2020) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbaa208 · Cited by 33 · see citing works
The Intersection and Dynamics between COVID-19, Health Disparities, and Adverse Childhood Experiences
Sonu, S. C., Marvin, D., & Moore, C. E. (2021) · Journal of Child & Adolescent Trauma · doi:10.1007/s40653-021-00363-z · Cited by 34 · see citing works
Adverse childhood experiences, depression, and cardiometabolic disease in a nationally representative sample
Salas, J., van den Berk‐Clark, C., Skiöld-Hanlin, S., Schneider, D., & Scherrer, J. F. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.109842 · Cited by 30 · see citing works
Adverse childhood experiences and early adolescent cyberbullying in the United States
Nagata, J. M., Trompeter, N., Singh, G., Raney, J. H., Ganson, K. T., Testa, A. M., Jackson, D. B., Murray, S. B., & Baker, F. C. (2022) · Journal of Adolescence · doi:10.1002/jad.12124 · Cited by 33 · see citing works
Psychosocial and environmental risk factors of obesity and hypertension in children and adolescents—a literature overview
Wójcik, M., Álvarez‐Pitti, J., Kozioł-Kozakowska, A., Brzeziński, M., Gabbianelli, R., Herceg-Čavrak, V., Wühl, E., Lucas, I., Radovanović, D. S., Melk, A., et al. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1268364 · Cited by 32 · see citing works
The Associations Between Adverse Childhood Experiences, Physical and Mental Health, and Physical Activity: A Scoping Review
Hadwen, B., Pila, E., & Thornton, J. S. (2022) · Journal of Physical Activity and Health · doi:10.1123/jpah.2022-0298 · Cited by 29 · see citing works
The importance of child abuse and neglect in adult medicine
Gordon, J. B. (2021) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2021.173268 · Cited by 28 · see citing works
Is early life adversity a trigger towards inflammageing?
Merz, M. P., & Turner, J. D. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111377 · Cited by 27 · see citing works
Childhood Adversity and Midlife Health: Shining a Light on the Black Box of Psychosocial Mechanisms
Bourassa, K. J., Moffitt, T. E., Harrington, H., Houts, R., Poulton, R., Ramrakha, S., Rasmussen, L. J. H., Wertz, J., & Caspi, A. (2022) · Prevention Science · doi:10.1007/s11121-022-01431-y · Cited by 27 · see citing works
Differing trajectories of adversity over the life course: Implications for adult health and well-being
Hajat, A., Nurius, P. S., & Song, C. (2020) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2020.104392 · Cited by 26 · see citing works
Validity and reliability of the Persian version of the Adverse Childhood Experiences Abuse Short Form
Chegeni, M., Haghdoost, A., Shahrbabaki, M. E., Shahrbabaki, P. M., & Nakhaee, N. (2020) · Journal of Education and Health Promotion · doi:10.4103/jehp.jehp_15_20 · Cited by 26 · see citing works
Promoting brain health through physical activity among adults exposed to early life adversity: Potential mechanisms and theoretical framework
Donofry, S. D., Stillman, C. M., Hanson, J. L., Sheridan, M. A., Sun, S., Loucks, E. B., & Erickson, K. I. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.09.051 · Cited by 27 · see citing works
Self-citation
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Lam-Hine, T., Riddell, C. A., Bradshaw, P. T., Omi, M., & Allen, A. M. (2023) · SSM - Population Health · doi:10.1016/j.ssmph.2023.101524 · Cited by 26 · see citing works
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Cavanagh, L., & Obasi, E. M. (2020) · Prevention Science · doi:10.1007/s11121-020-01141-3 · Cited by 27 · see citing works
The association between adverse childhood experiences and adult traumatic brain injury/concussion: a scoping review
Ma, Z., Bayley, M. T., Perrier, L., Dhir, P., Dépatie, L., Comper, P., Ruttan, L., Lay, C., & Munce, S. E. P. (2019) · Disability and Rehabilitation · doi:10.1080/09638288.2018.1424957 · Cited by 27 · see citing works
Cardiovascular disease and meaning in life: A systematic literature review and conceptual model
Vos, J. (2021) · Palliative & Supportive Care · doi:10.1017/s1478951520001261 · Cited by 24 · see citing works
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Harada, M., Guerrero, A. D., Iyer, S. N., Slusser, W. M., Szilagyi, M. A., & Koolwijk, I. (2021) · Academic Pediatrics · doi:10.1016/j.acap.2021.05.024 · Cited by 24 · see citing works
Effects of Early Life Adversity on Pubertal Timing and Tempo in Black and White Girls: The National Growth and Health Study
Hamlat, E. J., Laraia, B. A., Bleil, M. E., Deardorff, J., Tomiyama, A. J., Mujahid, M. S., Shields, G. S., Brownell, K., Slavich, G. M., & Epel, E. S. (2022) · Psychosomatic Medicine · doi:10.1097/psy.0000000000001048 · Cited by 24 · see citing works
Childhood Emotional Neglect and Cardiovascular Disease: A Narrative Review
Salzmann, S., Salzmann-Djufri, M., & Euteneuer, F. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.815508 · Cited by 24 · see citing works
Poor Family Relationships in Adolescence and the Risk of Premature Death: Findings from the Stockholm Birth Cohort Study
Alm, S., Låftman, S. B., & Bohman, H. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16101690 · Cited by 23 · see citing works
Adverse childhood experiences and traumatic brain injury among adolescents: findings from the 2016–2018 National Survey of Children’s Health
Jackson, D. B., Posick, C., Vaughn, M. G., & Testa, A. M. (2021) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-020-01687-1 · Cited by 23 · see citing works
Adverse Childhood Experiences and Cardiovascular Risk among Young Adults: Findings from the 2019 Behavioral Risk Factor Surveillance System
Jackson, D. B., Testa, A. M., Woodward, K. P., Qureshi, F., Ganson, K. T., & Nagata, J. M. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191811710 · Cited by 23 · see citing works
Childhood adversity and cardiometabolic biomarkers in mid-adulthood in the 1958 British birth cohort
Miller, N. E., & Lacey, R. E. (2022) · SSM - Population Health · doi:10.1016/j.ssmph.2022.101260 · Cited by 23 · see citing works
Contemporary Developments and Perspectives in International Health Security - Volume 1
Stawicki, S. P., Firstenberg, M. S., Galwankar, S. C., Izurieta, R., & Papadimos, T. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.84766 · Cited by 23 · see citing works
Adverse childhood experience, adopting a healthy lifestyle in adulthood, and risk of cardiovascular diseases
Qiao, Y., Zhu, D., Zhao, M., Magnussen, C. G., & Xi, B. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.07.023 · Cited by 23 · see citing works
Prevalence of adverse childhood experiences and their relationship to mental and physical illnesses in the Eastern Region of Saudi Arabia
AlHemyari, A. H., Al-Zamil, N. A., Shaikh, A. Y., Al‐Eidi, D. A., Al‐Dahlan, H. W., & Al‐Shamekh, S. S. (2022) · Brain and Behavior · doi:10.1002/brb3.2668 · Cited by 22 · see citing works
Life-Course Brain Health as a Determinant of Late-Life Mental Health: American Association for Geriatric Psychiatry Expert Panel Recommendations
Eyre, H. A., Stirland, L., Jeste, D. V., Reynolds, C. F., Berk, M., Ibáñez, A. M., Dawson, W. D., LAWLOR, B. A., Leroi, I., Yaffe, K. S., et al. (2023) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2023.09.013 · Cited by 23 · see citing works
Early life adversity influences stress response association with smoking relapse
Al’Absi, M., Lemieux, A. M., Westra, R., & ALLEN, S. S. (2017) · Psychopharmacology · doi:10.1007/s00213-017-4724-4 · Cited by 22 · see citing works
Childhood adversity and deviant peers: Considering behavioral selection and cultural socialization pathways
Trinidad, J. E. (2020) · Children and Youth Services Review · doi:10.1016/j.childyouth.2020.105844 · Cited by 21 · see citing works
Allostatic load and incident heart failure in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study
Park, C. C., Ringel, J. B., Pinheiro, L. C., Morris, A. A., Sterling, M. R., Balkan, L., Banerjee, S., Levitan, E. B., Safford, M. M., & Goyal, P. (2023) · BMC Cardiovascular Disorders · doi:10.1186/s12872-023-03371-z · Cited by 21 · see citing works
Adverse childhood experiences among Latina women and its association with mastery of stress and health
Alvarez, C., Perrin, N., Fernández, M. L., Rodriguez, R., & Glass, N. E. (2019) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2019.05.004 · Cited by 21 · see citing works
Depressive Symptoms, Antidepressants, and Clinical Outcomes in Chronic Kidney Disease: Findings from the CRIC Study
Hernández, R., Xie, D., Wang, X. B., Jordan, N., Ricardo, A. C., Anderson, A. H., Diamantidis, C. J., Kusek, J. W., Yaffe, K. S., Lash, J. P., et al. (2024) · Kidney Medicine · doi:10.1016/j.xkme.2024.100790 · Cited by 20 · see citing works
Adverse Childhood Experiences: Health Care Utilization And Expenditures In Adulthood
Selden, T. M., Bernard, D., Decker, S. L., & Fang, Z. (2024) · Health Affairs · doi:10.1377/hlthaff.2023.01271 · Cited by 20 · see citing works
Social Determinants of Cardiovascular Health in African American Children With CKD: An Analysis of the Chronic Kidney Disease in Children (CKiD) Study
Sgambat, K., Roem, J., Brady, T. M., Flynn, J. T., Mitsnefes, M. M., Samuels, J., Warady, B. A., Furth, S. L., & Moudgil, A. (2021) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2020.11.013 · Cited by 20 · see citing works
Adverse childhood experiences and lifetime adverse maternal outcomes (gestational diabetes and hypertensive disorders of pregnancy) in the Hispanic Community Health Study/Study of Latinos
Stanhope, K. K., Cammack, A. L., Perreira, K. M., Fernández‐Rhodes, L., Cordero, C., Gallo, L. C., Isasi, C. R., Castañeda, S. F., Daviglus, M. L., Kominiarek, M. A., et al. (2020) · Annals of Epidemiology · doi:10.1016/j.annepidem.2020.08.004 · Cited by 19 · see citing works
The role of welfare regimes in the relationship between childhood economic stress and adult health: a multilevel study of 20 European countries
Widding‐Havneraas, T., & Pedersen, S. H. (2020) · SSM - Population Health · doi:10.1016/j.ssmph.2020.100674 · Cited by 19 · see citing works
Adverse childhood experiences, sex, and cardiovascular habituation to repeated stress
Tyra, A. T., Cook, T. E., Young, D. A., Hurley, P. E., Oosterhoff, B. J., John‐Henderson, N. A., & Ginty, A. T. (2021) · Biological Psychology · doi:10.1016/j.biopsycho.2021.108175 · Cited by 19 · see citing works
Childhood adversity and risk of type 2 diabetes in early adulthood: results from a population-wide cohort study of 1.2 million individuals
Elsenburg, L. K., Bengtsson, J., Rieckmann, A., & Rod, N. H. (2023) · Diabetologia · doi:10.1007/s00125-023-05911-w · Cited by 19 · see citing works
Status of Maternal Cardiovascular Health in American Indian and Alaska Native Individuals: A Scientific Statement From the American Heart Association
Sharma, G. V., Kelliher, A., Deen, J. F., Parker, T., Hagerty, T., Choi, E. E., DeFilippis, E. M., Harn, K., Dempsey, R. J., Lloyd‐Jones, D. M., et al. (2023) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/hcq.0000000000000117 · Cited by 19 · see citing works
Parental absence in early childhood and onset of smoking and alcohol consumption before adolescence
Lacey, R. E., Zilanawala, A., Webb, E. A., Abell, J. G., & Bell, S. (2016) · Archives of Disease in Childhood · doi:10.1136/archdischild-2016-310444 · Cited by 19 · see citing works
Association Between Early Trauma and Ideal Cardiovascular Health Among Black Americans
Islam, S. J., Kim, J. H., Joseph, E., Topel, M. L., Baltrus, P., Liu, C., Ko, Y., Almuwaqqat, Z., Mujahid, M. S., Sims, M., et al. (2021) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/circoutcomes.121.007904 · Cited by 19 · see citing works
Adverse childhood experiences and their influence on psychological well-being and emotional intelligence among university students
Irshad, S., & Lone, A. (2025) · BMC Psychology · doi:10.1186/s40359-025-02565-8 · Cited by 18 · see citing works
The Intersection of Neighborhood Environment and Adverse Childhood Experiences: Methods for Creation of a Neighborhood ACEs Index
Schroeder, K., Dumenci, L., Sarwer, D. B., Noll, J. G., Henry, K., Suglia, S. F., Forke, C. M., & Wheeler, D. C. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19137819 · Cited by 18 · see citing works
Maternal childhood and lifetime traumatic life events and infant bronchiolitis
Adgent, M. A., Elsayed‐Ali, O., Gebretsadik, T. S., Tylavsky, F. A., Koçak, M., Cormier, S. A., Wright, R. J., & Carroll, K. N. (2019) · Paediatric and Perinatal Epidemiology · doi:10.1111/ppe.12559 · Cited by 18 · see citing works
Trends in inequality of opportunity in health over the life cycle: The role of early-life conditions
Kovačič, M., & Orso, C. E. (2022) · Journal of Economic Behavior & Organization · doi:10.1016/j.jebo.2022.07.018 · Cited by 16 · see citing works
Social, Economic, Technological, and Environmental Factors Affecting Cardiovascular Diseases: A Systematic Review and Thematic Analysis
Alizadeh, G., Gholipour‎, K., Aghdash, S. A., Dehnavieh, R., Jafarabadi, M. A., Azmin, M., & Zarnaq, R. K. (2022) · International Journal of Preventive Medicine · doi:10.4103/ijpvm.ijpvm_105_20 · Cited by 20 · see citing works
Adolescent Childbirth Is Associated With Greater Framingham Risk Scores for Cardiovascular Disease Among Participants of the IMIAS (International Mobility in Aging Study)
Rosendaal, N. T. A., Alvarado, B., Wu, Y. Y., Vélez, M. P., da Câmara, S. M. A., & Pirkle, C. M. (2017) · Journal of the American Heart Association · doi:10.1161/jaha.117.007058 · Cited by 17 · see citing works
Network analysis of adverse childhood experiences and cardiovascular diseases
Lee, C., Cao, J., Eagen‐Torkko, M. K., & Mohammed, S. A. (2023) · SSM - Population Health · doi:10.1016/j.ssmph.2023.101358 · Cited by 17 · see citing works

Association of Adverse Childhood Experiences With Cardiovascular Disease Later in Life
Godoy, L. C., Frankfurter, C., Cooper, M., Lay, C. L., Maunder, R., & Farkouh, M. E. (2020) · JAMA Cardiology · doi:10.1001/jamacardio.2020.6050 · Cited by 243 · see citing works
Adverse Childhood Experiences and the Cardiovascular Health of Children: A Cross-Sectional Study
(2015) · Apple Academic Press eBooks · doi:10.1201/b18313-19
Adverse Childhood Experiences Association with Adulthood Cardiovascular Disease Risks and Development: A Narrative Literature Review
Riedmann, C. A. (2024) · D-Scholarship@Pitt (University of Pittsburgh)
Childhood Adversity and Cardiovascular Disease; Current Knowledge and Future Directions
Suglia, S. (2025) · Current Cardiology Reports · doi:10.1007/s11886-025-02300-0
Associations of Adverse Childhood Experiences with Risk of Cardiovascular Disease in Later LifePreprint
Chen, Z. Y., Zhang, Y.-B., Sha, S., Zhang, Q., Su, Z., Cheung, T. C. C., Ungvari, G. S., Jackson, T., Feng, Y., & Xiang, Y. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5319125

Authors: Su, S., Jimenez, M. P., Roberts, C. T. F., & Loucks, E. B.
Affiliations: Augusta University (US)
Brown University (US)
Corresponding author: Su, Shaoyong
ORCID: Su, Shaoyong
Jimenez, Marcia P.
Loucks, Eric B.
Venue: Current Cardiology Reports
Publisher: Springer Science and Business Media LLC
Published: 2015-08-20
Volume: 17
Issue: 10
Pages: 88-88
ISSN: 1523-3782 (ISSN-L)
1534-3170
DOI: 10.1007/s11886-015-0645-1
PMC: PMC4941633
OpenAlex: W1193057051
Semantic Scholar: 7f2d7686921b6c238a884894b1a2dfacd08c21fe
Cited by: 242
References: 120
Citations by year: 2026: 17 · 2025: 21 · 2024: 30 · 2023: 31 · 2022: 34 · 2021: 38 · 2020: 26 · 2019: 16 · 2018: 13 · 2017: 10 · 2016: 5
FWCI: 1.34
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.springer.com/tdm (tdm)
Locations: Current Cardiology Reports (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Aging (R01AG048825, RC2AG036666)
National Heart, Lung, and Blood Institute (R01HL125577)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (T32HD007338)
Topics: Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
Social Sciences › Health › Intimate Partner and Family Violence
Social Sciences › Safety Research › Child Welfare and Adoption
Keywords: adverse childhood experiences, childhood abuse, child neglect, household dysfunction, cardiovascular risk, cardiovascular risk factors, biological pathways, epigenetics, developmental origins of health and disease, public health implications
MeSH terms: Adaptation, Physiological, Adaptation, Psychological, Adult, Cardiovascular Diseases, Child, Child Abuse, Depression, Diabetes Mellitus, Type 2, Humans, Life Change Events, Obesity, Risk Factors, Time Factors, Prevalence, Crime Victims, Substance-Related Disorders

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The role of adverse childhood experiences in cardiovascular disease risk: a review with emphasis on plausible mechanisms

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