Intramuscular adipose tissue attenuates gains in muscle quality in older adults at high risk for falling. A brief report
Open accessAbstract
OBJECTIVES: To examine the influence of intramuscular adipose tissue (IMAT) on muscle quality (MQ) changes in older adults after 12 weeks of exercise training. DESIGN: Prospective cohort design. SETTING: Academic health science center clinical exercise facility. PARTICIPANTS: 70 older (mean age 73.4 ± 6.3 years) adults with a history of falls. INTERVENTION: Resistance, endurance and balance exercise three times weekly for 12 weeks. MEASUREMENTS: Quadriceps strength was determined by maximum voluntary isometric contraction. An MRI of the thigh was used to determine cross-sectional area of lean tissue and IMAT. MQ was calculated as the force per unit area of lean tissue. Individuals were stratified into tertiles (Low IMAT, Middle IMAT, High IMAT) based on pre-IMAT levels. Changes in MQ, lean and IMAT were compared across groups. RESULTS: No significant changes in lean or IMAT occurred in any group with training. MQ increased only in the Low IMAT group. The Middle and High IMAT groups did not demonstrate a significant change in MQ following 12 weeks of training. Low IMAT, pre = 2.7 [0.6] post= 3.0 [0.6]; Middle IMAT, pre =2.54 [0.8] post =2.75 [0.7]; High IMAT, pre =2.6 [0.6] to post =2.5 [0.6]. CONCLUSION: High levels of thigh IMAT appear to blunt the adaptive MQ response to training. High levels of thigh IMAT may be a potential reason why some older adults do not change their MQ following training. Future research should confirm these results and determine why IMAT impairs MQ and the adaptive response to training in older adults.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In older adults, the quality of knee extensor muscle in response to a combined RT, endurance, and balance training intervention only improved in subjects with low thigh IMAT at baseline.
“A recent study in older adults showed that the quality of knee extensor muscle in response to a combined RT, endurance, and balance training intervention only improved in subjects with low thigh IMAT at baseline (21).”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Goodpaster, B. H., Park, S. W., Harris, T. B., Kritchevsky, S. B., Nevitt, M., Schwartz, A. V., Simonsick, E. M., Tylavsky, F. A., Visser, M., Newman, A. B., et al. (2006) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/61.10.1059 · Cited by 3,083 · cited 2× · see citing works
“This is reflected by a demonstrated decrease in muscle quality (MQ), or the force per unit area of lean tissue (1, 3, 4).”
Longitudinal study of muscle strength, quality, and adipose tissue infiltration
Delmonico, M. J., Harris, T. B., Visser, M., Park, S. W., Conroy, M. B., Velasquez-Mieyer, P., Boudreau, R., Manini, T. M., Nevitt, M., Newman, A. B., et al. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28047 · Cited by 1,446 · see citing works
Aging of skeletal muscle: a 12-yr longitudinal study
Frontera, W. R., Hughes, V. A., Fielding, R. A., Fiatarone, M. A., Evans, W. J., & Roubenoff, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.4.1321 · Cited by 1,443 · see citing works
Visser, M., Goodpaster, B. H., Kritchevsky, S. B., Newman, A. B., Nevitt, M., Rubin, S. M., Simonsick, E. M., Harris, T. B., & Study, F. T. H. A. (2005) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/60.3.324 · Cited by 1,403 · see citing works
Attenuation of skeletal muscle and strength in the elderly: the Health ABC Study
Goodpaster, B. H., Carlson, C. L., Visser, M., Kelley, D. E., Scherzinger, A., Harris, T. B., Stamm, E., & Newman, A. B. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.6.2157 · Cited by 1,226 · see citing works
Insulin sensitivity: Modulation by nutrients and inflammation
Schenk, S., Saberi, M., & Olefsky, J. M. (2008) · Journal of Clinical Investigation · doi:10.1172/jci34260 · Cited by 1,191 · see citing works
Individual differences in response to regular physical activity
BOUCHARD, C., & RANKINEN, T. (2001) · Medicine and Science in Sports and Exercise · doi:10.1097/00005768-200106001-00013 · Cited by 939 · see citing works
Visser, M., Kritchevsky, S. B., Goodpaster, B. H., Newman, A. B., Nevitt, M., Stamm, E., & Harris, T. B. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50217.x · Cited by 845 · see citing works
The diseasome of physical inactivity – and the role of myokines in muscle–fat cross talk
Pedersen, B. K. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.179515 · Cited by 631 · see citing works
Skeletal muscle fat infiltration: impact of age, inactivity, and exercise
Marcus, R. L., Addison, O., Kidde, J. P., Dibble, L. E., & Lastayo, P. C. (2010) · The Journal of nutrition, health and aging · doi:10.1007/s12603-010-0081-2 · Cited by 449 · see citing works
Self-citationGoodpaster, B. H., Chomentowski, P., Ward, B. K., Rossi, A., Glynn, N. W., Delmonico, M. J., Kritchevsky, S. B., Pahor, M., & Newman, A. B. (2008) · Journal of Applied Physiology · doi:10.1152/japplphysiol.90425.2008 · Cited by 446 · see citing works
Cesari, M., Kritchevsky, S. B., Baumgartner, R., Atkinson, H. H., Penninx, B. W. J. H., Lenchik, L., Palla, S. L., Ambrosius, W. T., Tracy, R. P., & Pahor, M. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn.82.2.428 · Cited by 422 · see citing works
Hilton, T. N., Tuttle, L. J., Bohnert, K. L., Mueller, M. J., & Sinacore, D. R. (2008) · Physical Therapy · doi:10.2522/ptj.20080079 · Cited by 373 · see citing works
Lang, T., Cauley, J. A., Tylavsky, F., Bauer, D., Cummings, S., & Harris, T. B. (2010) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.090807 · Cited by 371 · see citing works
Muscle quality. II. Effects of strength training in 65- to 75-yr-old men and women
Tracy, B. L., Ivey, F. M., Hurlbut, D., Martel, G. F., Lemmer, J. T., Siegel, E. L., Metter, E. J., Fozard, J. L., Fleg, J. L., & Hurley, B. F. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.86.1.195 · Cited by 371 · see citing works
Cesari, M., Kritchevsky, S. B., Baumgartner, R., et al. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.2.428 · Cited by 345 · see citing works
Intramuscular adipose tissue, sarcopenia, and mobility function in older individuals
Marcus, R. L., Addison, O., Dibble, L. E., Foreman, K. B., Morrell, G., & LaStayo, P. (2012) · Journal of Aging Research · doi:10.1155/2012/629637 · Cited by 296 · see citing works
Self-citationEffects of Strength Training and Detraining on Muscle Quality: Age and Gender Comparisons
Ivey, F. M., Tracy, B. L., Lemmer, J. T., NessAiver, M., Metter, E. J., Fozard, J. L., & Hurley, B. F. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.3.b152 · Cited by 247 · see citing works
Muscle Quality and Age: Cross-Sectional and Longitudinal Comparisons
Metter, E. J., Lynch, N. A., CONWIT, R. A., Lindle, R. S., Tobin, J. D., & Hurley, B. F. (1999) · The Journals of Gerontology Series A · doi:10.1093/gerona/54.5.b207 · Cited by 236 · see citing works
Inflammation and Race and Gender Differences in Computerized Tomography‐measured Adipose Depots
Beasley, L. E., Koster, A., Newman, A. B., Javaid, M. K., Ferrucci, L., Kritchevsky, S. B., Kuller, L. H., Pahor, M., Schaap, L. A., Visser, M., et al. (2009) · Obesity · doi:10.1038/oby.2008.627 · Cited by 234 · see citing works
Ryan, A. S., & Nicklas, B. J. (2004) · Diabetes Care · doi:10.2337/diacare.27.7.1699 · Cited by 207 · see citing works
Individual responses to combined endurance and strength training in older adults.
KARAVIRTA, L., HÄKKINEN, K., KAUHANEN, A., ARIJA-BLÁZQUEZ, A., SILLANPÄÄ, E., RINKINEN, N., & HÄKKINEN, A. (2011) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181f1bf0d · Cited by 139 · see citing works
Marcus, R. L., Smith, S., Morrell, G., Addison, O., Dibble, L. E., Wahoff-Stice, D., & LaStayo, P. C. (2008) · Physical Therapy · doi:10.2522/ptj.20080124 · Cited by 137 · see citing works
Self-citationBruunsgaard, H., Bjerregaard, E., Schroll, M., & Pedersen, B. K. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52061.x · Cited by 109 · see citing works
Tipping the scale: muscle versus fat
Rodeheffer, M. S. (2010) · Nature Cell Biology · doi:10.1038/ncb0210-102 · Cited by 51 · see citing works
Peterson, M. D., Liu, D., Gordish-Dressman, H., Hubal, M. J., Pistilli, E., Angelopoulos, T. J., Clarkson, P. M., Moyna, N. M., Pescatello, L. S., Seip, R. L., et al. (2011) · International Journal of Obesity · doi:10.1038/ijo.2010.257 · Cited by 39 · see citing works
Skeletal muscle fat infiltration: Impact of age, inactivity, and exercise
Marcus, R. L., Addison, O. R., Kidde, J., Dibble, L. E., & LaStayo, P. C. (2010) · The journal of nutrition health & aging · doi:10.1007/s12603-009-0230-7 · Cited by 13 · see citing works
Self-citationSmith, S., Addison, O. R., Morrell, G., Lee, D., Wahoff‐Stice, D., LaStayo, P. C., & Marcus, R. L. (2008) · Cardiopulmonary Physical Therapy Journal · doi:10.1097/01823246-200819040-00035 · Cited by 8 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Intermuscular fat: a review of the consequences and causes
Addison, O., Marcus, R. L., LaStayo, P. C., & Ryan, A. S. (2014) · International Journal of Endocrinology · doi:10.1155/2014/309570 · Cited by 656 · see citing works
Self-citationCorrea-de-Araujo, R., Addison, O., Miljkovic, I., Goodpaster, B. H., Bergman, B. C., Clark, R. V., Elena, J. W., Esser, K. A., Ferrucci, L., Harris-Love, M. O., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00963 · Cited by 468 · see citing works
Self-citationSarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss
Kirwan, R., McCullough, D., Butler, T., de Heredia, F. P., Davies, I. G., & Stewart, C. E. (2020) · GeroScience · doi:10.1007/s11357-020-00272-3 · Cited by 331 · see citing works
The obesity paradox and osteoporosis
Fassio, A., Idolazzi, L., Rossini, M., Gatti, D., Adami, G., Giollo, A., & Viapiana, O. (2018) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-018-0505-2 · Cited by 227 · see citing works
Infiltration of intramuscular adipose tissue impairs skeletal muscle contraction
Biltz, N. K., Collins, K. H., Shen, K. C., Schwartz, K., Harris, C. A., & Meyer, G. A. (2020) · The Journal of Physiology · doi:10.1113/jp279595 · Cited by 214 · see citing works
Intramuscular fat and inflammation differ in older adults: The impact of frailty and inactivity
Addison, O. R., Drummond, M. J., LaStayo, P. C., Dibble, L. E., Wende, A. R., McClain, D. A., & Marcus, R. L. (2014) · The journal of nutrition health & aging · doi:10.1007/s12603-014-0019-1 · Cited by 181 · see citing works
Self-citationUezumi, A., Ikemoto‐Uezumi, M., Zhou, H., Kurosawa, T., Yoshimoto, Y., Nakatani, M., Hitachi, K., Yamaguchi, H., Wakatsuki, S., Araki, T., et al. (2020) · Journal of Clinical Investigation · doi:10.1172/jci139617 · Cited by 166 · see citing works
Nicklas, B. J., Chmelo, E., Delbono, O., Carr, J. J., Lyles, M. F., & Marsh, A. P. (2015) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.105270 · Cited by 144 · see citing works
Sarcopenia: a potential cause and consequence of type 2 diabetes in Australia's ageing population?
Scott, D. S., de Courten, B. V., & Ebeling, P. R. (2016) · The Medical Journal of Australia · doi:10.5694/mja16.00446 · Cited by 119 · see citing works
Ageing, adipose tissue, fatty acids and inflammation
Pararasa, C., Bailey, C. J., & Griffiths, H. R. (2015) · Biogerontology · doi:10.1007/s10522-014-9536-x · Cited by 110 · see citing works
Essential amino acid supplementation in patients following total knee arthroplasty
Dreyer, H. C., Strycker, L. A., Senesac, H. A., Hocker, A. D., Smolkowski, K., Shah, S. N., & Jewett, B. A. (2013) · Journal of Clinical Investigation · doi:10.1172/jci70160 · Cited by 101 · see citing works
Harris‐Love, M. O., Seamon, B. A., Teixeira, C., & Ismail, C. (2016) · PeerJ · doi:10.7717/peerj.1721 · Cited by 93 · see citing works
Avesani, C. M., de Abreu, A. M., Ribeiro, H. S., Brismar, T. B., Stenvinkel, P., Sabatino, A., & Lindholm, B. (2023) · Journal of Nephrology · doi:10.1007/s40620-022-01553-0 · Cited by 76 · see citing works
Pedroso, M., de Almeida, A. C., Aily, J., de Noronha, M. D., & Mattiello, S. (2019) · Rheumatology International · doi:10.1007/s00296-019-04271-2 · Cited by 61 · see citing works
The effects of myosteatosis on skeletal muscle function in older adults
Dondero, K., Friedman, B., Rekant, J., Landers‐Ramos, R., & Addison, O. (2024) · Physiological Reports · doi:10.14814/phy2.16042 · Cited by 63 · see citing works
Self-citationFrank-Wilson, A. W., Farthing, J. P., Chilibeck, P. D., Arnold, C. M., Davison, K. S., Olszynski, W. P., & Kontulainen, S. A. (2016) · Osteoporosis International · doi:10.1007/s00198-016-3514-x · Cited by 60 · see citing works
Konopka, A. R., Wolff, C. A., Suer, M. K., & Harber, M. P. (2018) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00030.2018 · Cited by 59 · see citing works
The biphasic and age-dependent impact of klotho on hallmarks of aging and skeletal muscle function
Clemens, Z. J., Sivakumar, S., Pius, A., Sahu, A., Shinde, S., Mamiya, H., Luketich, N., Cui, J., Dixit, P. D., Hoeck, J. D., et al. (2021) · eLife · doi:10.7554/elife.61138 · Cited by 51 · see citing works
Pua, Y., Seah, F. J., Seet, F. J., Tan, J. W., Liaw, J. S., & Chong, H. (2015) · Arthritis Care & Research · doi:10.1002/acr.22584 · Cited by 50 · see citing works
de Almeida, A. C., Aily, J., Pedroso, M., Gonçalves, G., Felinto, J. D. C., Ferrari, R., Pastre, C. M., & Mattiello, S. (2019) · Clinical Rheumatology · doi:10.1007/s10067-019-04892-9 · Cited by 37 · see citing works
Perkisas, S., Cock, A. D., Verhoeven, V., & Vandewoude, M. F. J. (2016) · European Geriatric Medicine · doi:10.1016/j.eurger.2015.12.016 · Cited by 43 · see citing works
Brown Fat Promotes Muscle Growth During Regeneration
Bryniarski, A. R., & Meyer, G. A. (2019) · Journal of Orthopaedic Research® · doi:10.1002/jor.24324 · Cited by 35 · see citing works
Resistance exercise with older fallers: its impact on intermuscular adipose tissue
Jacobs, J. L., Marcus, R. L., Morrell, G., & LaStayo, P. (2014) · BioMed Research International · doi:10.1155/2014/398960 · Cited by 34 · see citing works
Self-citationConte, M., Vasuri, F., Bertaggia, E., Armani, A., Santoro, A., Bellavista, E., Degiovanni, A., D’Errico, A., Trisolino, G., Capri, M., et al. (2015) · Biogerontology · doi:10.1007/s10522-014-9549-5 · Cited by 34 · see citing works
Quercetin attenuates adipogenesis and fibrosis in human skeletal muscle
Ohmae, S., Akazawa, S., Takahashi, T., Izumo, T., Rogi, T., & Nakai, M. (2022) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2022.05.033 · Cited by 29 · see citing works
Clark, L. A., Russ, D. W., Tavoian, D., Arnold, W. D., Law, T., France, C. R., & Clark, B. C. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111437 · Cited by 26 · see citing works
Vitale, J. A., Messina, C., Albano, D., Fascio, E., Galbusera, F., Corbetta, S., Sconfienza, L. M., & Banfi, G. (2021) · Gerontology · doi:10.1159/000513597 · Cited by 26 · see citing works
Muscle Quality in Older Adults
Straight, C. R., Brady, A. O., & Evans, E. M. (2013) · American Journal of Lifestyle Medicine · doi:10.1177/1559827613510681 · Cited by 23 · see citing works
The Role of Imaging Biomarkers in the Assessment of Sarcopenia
Sanz‐Requena, R., Martínez‐Arnau, F. M., Pablos, A., Flor-Rufino, C., Barrachina-Igual, J., García‐Martí, G., Martí‐Bonmatí, L., & Pérez‐Ros, P. (2020) · Diagnostics · doi:10.3390/diagnostics10080534 · Cited by 22 · see citing works
Frank-Wilson, A. W., Farthing, J. P., Chilibeck, P. D., Arnold, C. M., Olszynski, W. P., & Kontulainen, S. A. (2014) · The journal of nutrition health & aging · doi:10.1007/s12603-014-0476-6 · Cited by 20 · see citing works
Davison, M. J., Maly, M. R., Keir, P. J., Hapuhennedige, S., Kron, A., Adachi, J. D., & BEATTIE, K. A. (2016) · Clinical Biomechanics · doi:10.1016/j.clinbiomech.2016.11.005 · Cited by 20 · see citing works
Modulación antioxidante y antiinflamatoria del ejercicio físico durante el envejecimiento
Galle, F. A., Martella, D., & Bresciani, G. (2018) · Revista Española de Geriatría y Gerontología · doi:10.1016/j.regg.2018.03.003 · Cited by 21 · see citing works
Mesinovic, J., Rodríguez, A. J., Cervo, M. M., Gandham, A., Xu, C. L. H., Glavas, C., de Courten, B. V., Zengin, A., Ebeling, P. R., & Scott, D. S. (2022) · European Journal of Nutrition · doi:10.1007/s00394-022-03038-z · Cited by 16 · see citing works
Scott, D. S., Joham, A. E., Teede, H. J., Gibson‐Helm, M. E., Harrison, C. L., Cassar, S., Hutchison, S. K., Ebeling, P. R., Stepto, N. K., & de Courten, B. V. (2016) · Nutrients · doi:10.3390/nu8120774 · Cited by 16 · see citing works
Body Composition and Falls Risk in Older Adults
Xu, C. L. H., Ebeling, P. R., & Scott, D. S. (2019) · Current Geriatrics Reports · doi:10.1007/s13670-019-00294-6 · Cited by 15 · see citing works
Fairfield, W. D., Minton, D. M., Elliehausen, C. J., Nichol, A. D., Cook, T. L., Rathmacher, J. A., Pitchford, L. M., Paluska, S. A., Kuchnia, A. J., Allen, J. M., et al. (2022) · Nutrients · doi:10.3390/nu14214674 · Cited by 13 · see citing works
Computer-based assessment for facioscapulohumeral dystrophy diagnosis
Chambers, O., Milenković, J., Pražnikar, A., & Tasič, J. F. (2015) · Computer Methods and Programs in Biomedicine · doi:10.1016/j.cmpb.2015.03.006 · Cited by 12 · see citing works
Holm, P. M., Blankholm, A. D., Nielsen, J. L., Bandholm, T., Wirth, W., Wisser, A., Kemnitz, J., Eckstein, F., Schrøder, H. M., Wernbom, M., et al. (2024) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2024.152390 · Cited by 11 · see citing works
Borghi, S., Bonato, M., Torre, A. L., Banfi, G., & Vitale, J. A. (2022) · Medicine · doi:10.1097/md.0000000000029744 · Cited by 12 · see citing works
Thigh Intramuscular Fat on Prognosis of Patients With Nonischemic Cardiomyopathy
Yoshida, T., Shibata, A., Tanihata, A., Hayashi, H., Yamaguchi, Y., Kitada, R., Ehara, S., Izumiya, Y., & Yoshiyama, M. (2022) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2021.12.059 · Cited by 11 · see citing works
Ribeiro, A. S., Oliveira, A. V., Kassiano, W., do Nascimento, M. A., Mayhew, J. L., & Cyrino, E. S. (2022) · Aging Clinical and Experimental Research · doi:10.1007/s40520-022-02313-7 · Cited by 10 · see citing works
An Automated and Robust Framework for Quantification of Muscle and Fat in the Thigh
Tan, C., Yan, Z., Zhang, S., Belaroussi, B., Yu, H. J., Miller, C. G., & Metaxas, D. (2014) · Proceedings - International Conference on Pattern Recognition/Proceedings/International Conference on Pattern Recognition · doi:10.1109/icpr.2014.547 · Cited by 10 · see citing works
Imani, M., Hassan, E. B., Vogrin, S., Ch’Ng, A. S. T. N., Lane, N. E., Cauley, J. A., & Duque, G. (2021) · Calcified Tissue International · doi:10.1007/s00223-021-00914-4 · Cited by 9 · see citing works
Nelson, C. M., Marchese, V. G., Rock, K., Henshaw, R. M., & Addison, O. R. (2020) · Frontiers in Pediatrics · doi:10.3389/fped.2020.00292 · Cited by 9 · see citing works
Self-citationVojciechowski, A. S., Silva, C. T. D. S., Rodrigues, E. V., Gallo, L. H., Filho, J. M., & Gomes, A. R. S. (2021) · Games for Health Journal · doi:10.1089/g4h.2020.0223 · Cited by 8 · see citing works
Al-Horani, R., Alsays, K. M., & Alrob, O. A. (2023) · European Journal of Applied Physiology · doi:10.1007/s00421-023-05370-6 · Cited by 7 · see citing works
Chen, N., Han, T., Liu, H., Cao, J., Liu, W., Zuo, D., Zhang, T., Lan, X., Jin, X., Weng, Y., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.935445 · Cited by 6 · see citing works
Yang, M., Zhou, F., Wang, C., sun, T., zhao, W., Liu, L., Meng, Y., & tian, L. (2026) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00473.2025 · Cited by 5 · see citing works
Orsatti, F. L., Nunes, P. R. P., Carneiro, M. A. S., Orsatti, C. L., & Souza, M. V. C. (2022) · Experimental Gerontology · doi:10.1016/j.exger.2022.111807 · Cited by 6 · see citing works
Rock, K., Addison, O. R., Gray, V. L., Henshaw, R. M., Ward, C., & Marchese, V. G. (2023) · Children · doi:10.3390/children10010114 · Cited by 5 · see citing works
Self-citationPrevalence of disability and associated functional limitations among older adults in Brazil
Souto, R. M. C. V., Corassa, R. B., Júnior, J. V. S., & Neto, O. L. D. M. (2024) · PLOS Global Public Health · doi:10.1371/journal.pgph.0003225 · Cited by 4 · see citing works
Nguyen-Khac, V., Bonnet-Lebrun, A., Linglart, A., Tienda, M. D., Berkenou, J., Mannes, I., Adamsbaum, C., Wicart, P., & Wafa Skalli, E. (2022) · Journal of the Endocrine Society · doi:10.1210/jendso/bvac135 · Cited by 4 · see citing works
Friedman, B., Beamer, B. A., Beans, J., Gray, V. L., Alon, G., Ryan, A. S., Katzel, L. I., Sorkin, J. D., & Addison, O. R. (2025) · JMIR Research Protocols · doi:10.2196/68082 · Cited by 3 · see citing works
Self-citationWong, A. K. O., Fung, H. J. W., Pretty, S. P., Laing, A. C., Chan, A. C. H., Mathur, S., Zabjek, K., Giangregorio, L., & Cheung, A. M. (2023) · JCSM Clinical Reports · doi:10.1002/crt2.58 · Cited by 3 · see citing works
Johnston, C., Dewig, D. R., Pietrosimone, B., Padua, D. A., Ryan, E. D., HART, J., Spang, J. T., & Blackburn, J. T. (2023) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003359 · Cited by 3 · see citing works
Hanifah, H., Pratiwi, Y. S., & Panjdi, T. D. (2020) · Althea Medical Journal · doi:10.15850/amj.v6n4.1755 · Cited by 3 · see citing works
Joumaa, V., Boldt, K., Han, S. K., Chun, K. J., & Herzog, W. (2021) · Spine · doi:10.1097/brs.0000000000004162 · Cited by 2 · see citing works
CIR-Myo News: Abstracts of the 2015 Spring Padua Muscle Days
Editors, T. L. O. (2015) · European Journal of Translational Myology · doi:10.4081/bam.2015.3.145
Towards large-scale MR thigh image analysis via an integrated quantification framework
Tan, C., Li, K., Yan, Z., Yi, J., Wu, P., Yu, H. J., Engelke, K., & Metaxas, D. (2016) · Neurocomputing · doi:10.1016/j.neucom.2016.05.108
CIR-Myo News: Abstracts of the 2015 Spring Padua Muscle Days
Editors, T. L. O. (2015) · European Journal of Translational Myology · doi:10.4081/ejtm.2015.5150
Impaired Muscle Performance in Older Adults
Marcus, R. L., Reidy, P. T., & LaStayo, P. C. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-60912-8.00016-6
Self-citationComplete Adipose Replacement of Bilateral Medial Gastrocnemius Muscle - A Cadaveric Case Report
Nichols, C., Liu, E., & Liu, H. (2020) · Academia Anatomica International · doi:10.21276/aanat.2020.6.1.14
Fontes, A. P., Cintra, R. M., Gomes, L., & Sousa, J. P. (2023) · International Journal of Research in Medical Sciences · doi:10.18203/2320-6012.ijrms20230157
Amput, P., & Wongphon, S. (2024) · Current Aging Science · doi:10.2174/0118746098294790240510063241
Intramuscular fat content and the risk of peritonitis in peritoneal dialysis patients
Xu, L., Ng, J. K., Fung, W. W., Chan, G. C., Pang, W., Chow, K., & Szeto, C. C. (2026) · Clinical Kidney Journal · doi:10.1093/ckj/sfag102
- Authors
- Marcus, R. L., Addison, O., & LaStayo, P. C.
- Affiliations
- University of Utah (US)
- Corresponding author
- Marcus, Robin L.
- LaStayo, Paul C.
- Venue
- The Journal of nutrition, health and aging
- Publisher
- Elsevier BV
- Published
- 2013-03
- Volume
- 17
- Issue
- 3
- Pages
- 215-218
- ISSN
- 1279-7707 (ISSN-L)
- PMC
- PMC12878942
- OpenAlex
- W2069912984
- Cited by
- 65
- References
- 27
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 6 · 2022: 9 · 2021: 6 · 2020: 8 · 2019: 5 · 2018: 3 · 2016: 7 · 2015: 6 · 2014: 6 · 2013: 2
- FWCI
- 3.00
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- The journal of nutrition health & aging (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- Funders
- National Institute on Aging (R01AG031255)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Keywords
- intramuscular fat, muscle quality, older adults, fall risk, exercise training, resistance training, balance training, endurance training, quadriceps strength, training effects, sarcopenia
- MeSH terms
- Accidental Falls, Adipose Tissue, Aged, Cross-Sectional Studies, Female, Humans, Isometric Contraction, Male, Prospective Studies, Risk Factors, Exercise, Muscle, Skeletal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
