Biology or Behavior: Which Is the Strongest Contributor to Weight Gain?

Byrne, Nuala M.; Hills, Andrew P.

doi:10.1007/s13679-012-0040-9

Cited by 13Regulation of Appetite and ObesityObesity, Physical Activity, DietEating Disorders and Behaviors

Biology or Behavior: Which Is the Strongest Contributor to Weight Gain?

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Byrne, Nuala M., Hills, Andrew P.·2013·Current Obesity Reports

DOI 10.1007/s13679-012-0040-9

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Many compensatory responses to ER and weight loss can be reversed following a 7- to 14-day period of energy balance post-weight loss.
“other research suggests that many of these responses can be reversed following a 7- to 14-day period of energy balance post-weight loss.1, 20”
From Intermittent energy restriction improves weight loss efficiency in obese men: the MATADOR study (2018) · cites this paper as [1]
The section “Metabolism Acts to Limit Losses in Body Weight (Energy Stores)” describes compensatory reductions in energy expenditure during energy restriction, supporting the premise that these responses occur. It does not say that many responses reverse after weight loss, or that 7–14 days of energy balance reverses them; searches for reversal and that interval found no such passage. Page numbers were not available in our copy. (LLM, conf=0.79)
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The global obesity pandemic: shaped by global drivers and local environments
Swinburn, B. A., Sacks, G., Hall, K. D., McPherson, K., Finegood, D. T., Moodie, M. L., & Gortmaker, S. L. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60813-1 · Cited by 4,888 · see citing works
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature · doi:10.1038/nature10777 · Cited by 4,810 · see citing works
Congenital leptin deficiency is associated with severe early-onset obesity in humans
Montague, C. T., Farooqi, I. S., Whitehead, J. P., Soos, M. A., Rau, H., Wareham, N. J., Sewter, C. P., Digby, J. E., Mohammed, S. N., Hurst, J. A., et al. (1997) · Nature · doi:10.1038/43185 · Cited by 2,936 · see citing works
The thrifty phenotype hypothesis
Hales, C. N., & Barker, D. J. (2001) · British Medical Bulletin · doi:10.1093/bmb/60.1.5 · Cited by 2,749 · see citing works
Obesity and the Environment: Where Do We Go from Here?
Hill, J. O., Wyatt, H. R., Reed, G. W., & Peters, J. C. (2003) · Science · doi:10.1126/science.1079857 · Cited by 2,180 · see citing works
THE BIOLOGY OF HUMAN STARVATION
Keys, A., BROŽEK, J., & Henschel, A. (1951) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1951.tb56499.x · Cited by 2,053 · see citing works
The Biology of Human Starvation: Volume I
KEYS, A., BROŽEK, J., HENSCHEL, A., MICKELSEN, O., & TAYLOR, H. L. (1950) · doi:10.5749/j.ctv9b2tqv · Cited by 2,039 · see citing works
Physiological adaptations to low-volume, high-intensity interval training in health and disease
Gibala, M. J., Little, J. P., MacDonald, M. J., & Hawley, J. A. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2011.224725 · Cited by 1,744 · see citing works
Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring
Ng, S.-F., Lin, R. C. Y., Laybutt, D. R., Barres, R., Owens, J. A., & Morris, M. J. (2010) · Nature · doi:10.1038/nature09491 · Cited by 1,327 · see citing works
The Response to Long-Term Overfeeding in Identical Twins
Bouchard, C., Tremblay, A., Després, J.-P., Nadeau, A., Lupien, P. J., Thériault, G., Dussault, J., Moorjani, S., Pinault, S., & Fournier, G. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005243222101 · Cited by 1,278 · see citing works
Quantification of the effect of energy imbalance on bodyweight
Hall, K. D., Sacks, G., Chandramohan, D., Chow, C. C., Wang, Y. C., Gortmaker, S. L., & Swinburn, B. A. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60812-x · Cited by 1,165 · see citing works
Changing the future of obesity: science, policy, and action
Gortmaker, S. L., Swinburn, B. A., Levy, D. T., Carter, R., Mabry, P. L., Finegood, D. T., Huang, T. T. ‐., Marsh, T., & Moodie, M. (2011) · The Lancet · doi:10.1016/s0140-6736(11)60815-5 · Cited by 927 · see citing works
How much physical activity is enough to prevent unhealthy weight gain? Outcome of the IASO 1st Stock Conference and consensus statement
Saris, W. H. M., Blair, S. N., Van Baak, M. A., Eaton, S. B., Davies, P. S. W., Di Pietro, L., Fogelholm, M., Rissanen, A., Schoeller, D., Swinburn, B., et al. (2003) · Obesity Reviews · doi:10.1046/j.1467-789x.2003.00101.x · Cited by 865 · see citing works
AMP-activated Protein Kinase Suppresses Protein Synthesis in Rat Skeletal Muscle through Down-regulated Mammalian Target of Rapamycin (mTOR) Signaling
Bolster, D. R., Crozier, S. J., Kimball, S. R., & Jefferson, L. S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.c200171200 · Cited by 851 · see citing works
Ten Putative Contributors to the Obesity Epidemic
McAllister, E. J., Dhurandhar, N. V., Keith, S. W., Aronne, L. J., Barger, J., Baskin, M., Benca, R. M., Biggio, J., Boggiano, M. M., Eisenmann, J. C., et al. (2009) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390903372599 · Cited by 710 · see citing works
Genetics of Obesity in Humans
Farooqi, I. S., & O’Rahilly, S. (2006) · Endocrine Reviews · doi:10.1210/er.2006-0040 · Cited by 583 · see citing works
A systematic review of environmental factors and obesogenic dietary intakes among adults: are we getting closer to understanding obesogenic environments?
Giskes, K., van Lenthe, F. J., Avendano‐Pabon, M., & Brug, J. (2010) · Obesity Reviews · doi:10.1111/j.1467-789x.2010.00769.x · Cited by 479 · see citing works
Short sleep duration increases energy intakes but does not change energy expenditure in normal-weight individuals
St-Onge, M.-P., Roberts, A. L., Chen, J., Kelleman, M., O’Keeffe, M., RoyChoudhury, A., & Jones, P. J. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.013904 · Cited by 463 · see citing works
The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives
Garland, T., Schutz, H., Chappell, M. A., Keeney, B. K., Meek, T. H., Copes, L. E., Acosta, W., Drenowatz, C., Maciel, R. C., van Dijk, G., et al. (2011) · Journal of Experimental Biology · doi:10.1242/jeb.048397 · Cited by 444 · see citing works
Changes in intake of fruits and vegetables in relation to risk of obesity and weight gain among middle-aged women
He, K., Hu, F. B., Colditz, G. A., Manson, J. E., Willett, W. C., & Liu, S. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802795 · Cited by 426 · see citing works
Energy metabolism, fuel selection and body weight regulation
Galgani, J. E., & Ravussin, É. (2008) · International Journal of Obesity · doi:10.1038/ijo.2008.246 · Cited by 372 · see citing works
How much physical activity is needed to minimize weight gain in previously obese women?
Schoeller, D., Shay, K., & Kushner, R. (1997) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.3.551 · Cited by 342 · see citing works
Endocrine markers of semistarvation in healthy lean men in a multistressor environment
Friedl, K. E., Moore, R. J., Hoyt, R. W., Marchitelli, L. J., Martinez-Lopez, L. E., & Askew, E. W. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.5.1820 · Cited by 316 · cited 1× · see citing works
“stimulating hormone, leutenizing hormone, and testosterone[46, 44], as well as reduced”
Background
Implications of nonshivering thermogenesis for energy balance regulation in humans
Lichtenbelt, W. D. V. M., & Schrauwen, P. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00652.2010 · Cited by 306 · see citing works
Associations of Gestational Weight Gain With Short- and Longer-term Maternal and Child Health Outcomes
Oken, E., KLEINMAN, K. P., Belfort, M. B., Hammitt, J. K., & Gillman, M. W. (2009) · American Journal of Epidemiology · doi:10.1093/aje/kwp101 · Cited by 302 · see citing works
Estimating the changes in energy flux that characterize the rise in obesity prevalence
Swinburn, B. A., Sacks, G., Lo, S. K., Westerterp, K. R., Rush, E. C., ROSENBAUM, M. S., Luke, A. H., Schoeller, D. A., DeLany, J. P., Butte, N. F., et al. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.27061 · Cited by 291 · see citing works
Overcoming policy cacophony on obesity: an ecological public health framework for policymakers
Lang, T., & Rayner, G. (2007) · Obesity Reviews · doi:10.1111/j.1467-789x.2007.00338.x · Cited by 290 · see citing works
Long‐Term Weight Loss and Breakfast in Subjects in the National Weight Control Registry
Wyatt, H. R., Grunwald, G. K., Mosca, C. L., Klem, M. L., Wing, R. R., & Hill, J. O. (2002) · Obesity Research · doi:10.1038/oby.2002.13 · Cited by 283 · see citing works
Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects
Rosenbaum, M., Vandenborne, K., Goldsmith, R., Simoneau, J.-A., Heymsfield, S., Joanisse, D. R., Hirsch, J., Murphy, E., Matthews, D., Segal, K. R., et al. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00474.2002 · Cited by 255 · cited 1× · see citing works
“Physical activity [20, 54] and the energy cost of movement [55, 56] reduce during energy restriction.”
Background
Appetite sensations and satiety quotient: Predictors of energy intake and weight loss
Drapeau, V., King, N., Hetherington, M., Doucet, E., Blundell, J., & Tremblay, A. (2007) · Appetite · doi:10.1016/j.appet.2006.08.002 · Cited by 248 · see citing works
Genetic determinants of common obesity and their value in prediction
Loos, R. J. F. (2012) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2011.11.003 · Cited by 247 · see citing works
Estimating the Energy Gap Among US Children: A Counterfactual Approach
Wang, Y. C., Gortmaker, S. L., Sobol, A. M., & Kuntz, K. M. (2006) · PEDIATRICS · doi:10.1542/peds.2006-0682 · Cited by 244 · see citing works
Gluttony and thermogenesis revisited
Stock, M. J. (1999) · International Journal of Obesity · doi:10.1038/sj.ijo.0801108 · Cited by 242 · cited 1× · see citing works
“However, not all researchers would concur with these conclusions, particularly when diets of different macronutrient content are considered [89].”
Background
Effect of calorie restriction on resting metabolic rate and spontaneous physical activity.
Martin, C. K., Heilbronn, L. K., de Jonge, L., DeLany, J. P., Volaufova, J., Anton, S. D., Redman, L. M., Smith, S. R., & Ravussin, E. (2007) · Obesity · doi:10.1038/oby.2007.354 · Cited by 237 · see citing works
The Effects of Exercise-Induced Weight Loss on Appetite-Related Peptides and Motivation to Eat
Martins, C., Kulseng, B., King, N. A., Holst, J. J., & Blundell, J. E. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2082 · Cited by 236 · see citing works
Hypothalamic neuropeptides and the regulation of appetite
Parker, J., & Bloom, S. R. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.02.004 · Cited by 233 · see citing works
Why do obese patients not lose more weight when treated with low-calorie diets? A mechanistic perspective
Heymsfield, S. B., Harp, J. B., Reitman, M. L., Beetsch, J. W., Schoeller, D. A., Erondu, N., & Pietrobelli, A. (2007) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.346 · Cited by 229 · see citing works
Effect of obesity and starvation on thyroid hormone, growth hormone, and cortisol secretion
Douyon, L., & SCHTEINGART, D. E. (2002) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(01)00023-8 · Cited by 222 · see citing works
Increase in Brown Adipose Tissue Activity after Weight Loss in Morbidly Obese Subjects
Vijgen, G. H. E. J., Bouvy, N. D., Teule, G. J. J., Brans, B. T., Joris Hoeks, J., Schrauwen, P., & Lichtenbelt, W. D. V. M. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1289 · Cited by 212 · see citing works
Do adaptive changes in metabolic rate favor weight regain in weight-reduced individuals? An examination of the set-point theory
Weinsier, R. L., Nagy, T. R., Hunter, G. R., Darnell, B. E., Hensrud, D. D., & Weiss, H. L. (2000) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.5.1088 · Cited by 208 · see citing works
Predicting metabolic adaptation, body weight change, and energy intake in humans
Hall, K. D. (2009) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00559.2009 · Cited by 203 · see citing works
Predictors of Weight Maintenance
Pasman, W. J., SARIS, W. H. M., & Westerterp‐Plantenga, M. S. (1999) · Obesity Research · doi:10.1002/j.1550-8528.1999.tb00389.x · Cited by 196 · see citing works
Physical Activity Patterns in the National Weight Control Registry
Catenacci, V. A., Ogden, L. G., Stuht, J., Phelan, S., Wing, R. R., Hill, J. O., & Wyatt, H. R. (2008) · Obesity · doi:10.1038/oby.2007.6 · Cited by 190 · see citing works
Free-living activity energy expenditure in women successful and unsuccessful at maintaining a normal body weight
Weinsier, R. L., Hunter, G. R., Desmond, R. A., Byrne, N. M., Zuckerman, P. A., & Darnell, B. E. (2002) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/75.3.499 · Cited by 188 · see citing works
Self-citation
<i>Changes of Basal Metabolic Rate in Man in Semistarvation and Refeeding</i>
Grande, F., Anderson, J. T., & Keys, A. (1958) · Journal of Applied Physiology · doi:10.1152/jappl.1958.12.2.230 · Cited by 181 · see citing works
Genetic Influences on the Response of Body Fat and Fat Distribution to Positive and Negative Energy Balances in Human Identical Twins
Bouchard, C., & Tremblay, A. (1997) · Journal of Nutrition · doi:10.1093/jn/127.5.943s · Cited by 180 · see citing works
CNS regulation of appetite
Harrold, J. A., Dovey, T. M., Blundell, J. E., & Halford, J. C. G. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.01.007 · Cited by 177 · see citing works
Rate and extent of compensatory changes in energy intake and expenditure in response to altered exercise and diet composition in humans
Stubbs, R. J., Hughes, D. A., Johnstone, A. M., Whybrow, S., Horgan, G. W., King, N. A., & Blundell, J. E. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00196.2003 · Cited by 169 · see citing works
Enhanced metabolic efficiency contributes to weight regain after weight loss in obesity-prone rats
MacLean, P. S., HIGGINS, J. A., Johnson, G. C., Fleming‐Elder, B. K., Donahoo, W. T., Melanson, E. L., & Hill, J. O. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00463.2004 · Cited by 162 · see citing works
Differential Acylated Ghrelin, Peptide YY3–36, Appetite, and Food Intake Responses to Equivalent Energy Deficits Created by Exercise and Food Restriction
King, J. A., Wasse, L. K., Ewens, J., Crystallis, K., Emmanuel, J. J., Batterham, R. L., & Stensel, D. J. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-2735 · Cited by 159 · see citing works
Adipose tissue and fetal programming
Symonds, M. E., Pope, M., Sharkey, D., & Budge, H. (2012) · Diabetologia · doi:10.1007/s00125-012-2505-5 · Cited by 150 · see citing works
Changing the Future of Obesity
Gortmaker, S. L., Swinburn, B. A., Levy, D. T., Carter, R., Mabry, P. L., Finegood, D. T., Huang, T. T. ‐., Marsh, T., & Moodie, M. (2012) · Obstetrical & Gynecological Survey · doi:10.1097/ogx.0b013e318242ee82 · Cited by 139 · see citing works
Skeletal muscle responses to negative energy balance: Effects of dietary protein
Carbone, J. W., McClung, J. P., & Pasiakos, S. M. (2012) · Advances in Nutrition · doi:10.3945/an.111.001792 · Cited by 138 · see citing works
Obesity epidemic in India: intrauterine origins?
Yajnik, C. S. (2004) · Proceedings of The Nutrition Society · doi:10.1079/pns2004365 · Cited by 138 · see citing works
Effect of Dietary Adherence with or without Exercise on Weight Loss: A Mechanistic Approach to a Global Problem
Corral, P. D., Chandler-Laney, P. C., Casazza, K., Gower, B. A., & Hunter, G. R. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-1057 · Cited by 128 · see citing works
Appetite sensations as a marker of overall intake
Drapeau, V., Blundell, J., Therrien, F., Lawton, C., Richard, D., & Tremblay, A. (2005) · British Journal of Nutrition · doi:10.1079/bjn20041312 · Cited by 125 · see citing works
Television Viewing and Long‐Term Weight Maintenance: Results from the National Weight Control Registry
Raynor, D. A., Phelan, S., Hill, J. O., & Wing, R. R. (2006) · Obesity · doi:10.1038/oby.2006.209 · Cited by 122 · see citing works
Central control of thermogenesis
Clapham, J. C. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.10.014 · Cited by 121 · see citing works
Chronic central neuropeptide Y infusion in normal rats: status of the hypothalamo-pituitary-adrenal axis, and vagal mediation of hyperinsulinaemia
Sainsbury, A., Rohner-Jeanrenaud, F., Cusin, I., Zakrzewska, K. E., Halban, P. A., Gaillard, R. C., & Jeanrenaud, B. (1997) · Diabetologia · doi:10.1007/s001250050820 · Cited by 115 · see citing works
Overfeeding and energy expenditure in humans
Tremblay, A., Després, J., Thériault, G., Fournier, G., & Bouchard, C. (1992) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/56.5.857 · Cited by 110 · see citing works
Adaptive thermogenesis can make a difference in the ability of obese individuals to lose body weight
Tremblay, A., Royer, M.-M., Chaput, J.-P., & Doucet, É. (2013) · International Journal of Obesity · doi:10.1038/ijo.2012.124 · Cited by 108 · see citing works
Resting energy expenditure in reduced-obese subjects in the National Weight Control Registry
Wyatt, H. R., Grunwald, G. K., Seagle, H. M., Klem, M. L., McGuire, M. T., Wing, R. R., & Hill, J. O. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.6.1189 · Cited by 108 · see citing works
Am J Physiol Regulatory Integrative Comp Physiol
Vranić, M., Riddell, M. C., Campbell, J. E., Kiràly, M. A., Atkinson, D. J., & D'souza, A. M. (2010) · Cited by 98 · see citing works
Physical Activity Patterns Using Accelerometry in the National Weight Control Registry
Catenacci, V. A., Grunwald, G. K., Ingebrigtsen, J. P., Jakicic, J. M., McDermott, M. D., Phelan, S., Wing, R. R., Hill, J. O., & Wyatt, H. R. (2010) · Obesity · doi:10.1038/oby.2010.264 · Cited by 96 · see citing works
Overfeeding Reduces Insulin Sensitivity and Increases Oxidative Stress, without Altering Markers of Mitochondrial Content and Function in Humans
Samocha‐Bonet, D., Campbell, L. V., Mori, T. A., Croft, K. D., Greenfield, J. R., Turner, N. A., & Heilbronn, L. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036320 · Cited by 92 · see citing works
Contribution of Energy Restriction and Macronutrient Composition to Changes in Adipose Tissue Gene Expression during Dietary Weight-Loss Programs in Obese Women
Capel, F., Viguerie, N., Véga, N., Dejean, S., Arner, P., Klimčáková, E., Martínez, J. A., Saris, W. H. M., Holst, C., Taylor, M. A., et al. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0814 · Cited by 90 · see citing works
Impact of Maternal Periconceptional Overnutrition on Fat Mass and Expression of Adipogenic and Lipogenic Genes in Visceral and Subcutaneous Fat Depots in the Postnatal Lamb
Rattanatray, L., MacLaughlin, S. M., Kleemann, D. O., Walker, S. K., Mühlhäusler, B. S., & McMillen, I. C. (2010) · Endocrinology · doi:10.1210/en.2010-0501 · Cited by 89 · see citing works
Role of the hypothalamus in the neuroendocrine regulation of body weight and composition during energy deficit
Sainsbury, A., & Zhang, L. (2011) · Obesity Reviews · doi:10.1111/j.1467-789x.2011.00948.x · Cited by 85 · see citing works
Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: the 1946 British Birth Cohort Study
Elks, C. E., Loos, R. J. F., Hardy, R., Wills, A. K., Wong, A., Wareham, N. J., Kuh, D. J., & Ong, K. K. (2012) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.027870 · Cited by 83 · see citing works
Lean-body-mass composition and resting energy expenditure before and after long-term overfeeding
Dériaz, O., Fournier, G., Tremblay, A., Després, J., & Bouchard, C. (1992) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/56.5.840 · Cited by 82 · see citing works
Leptin concentrations in response to acute stress predict subsequent intake of comfort foods
Tomiyama, A. J., Schamarek, I., Lustig, R. H., Kirschbaum, C., Puterman, E. M., Havel, P. J., & Epel, E. S. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.04.021 · Cited by 79 · see citing works
Comment on "Obesity and the Environment: Where Do We Go from Here?"
Butte, N. F., & Ellis, K. J. (2003) · Science · doi:10.1126/science.1085985 · Cited by 76 · see citing works
Exercise-induced energy expenditure: Implications for exercise prescription and obesity
Colley, R. C., Hills, A. P., King, N. A., & Byrne, N. M. (2010) · Patient Education and Counseling · doi:10.1016/j.pec.2010.03.001 · Cited by 74 · see citing works
Self-citation
Identification of Adipocyte Genes Regulated by Caloric Intake
Franck, N., Gummesson, A., Jernås, M., Glad, C. A. M., Svensson, P., Guillot, G., Rudemo, M., Nyström, F. H., Carlsson, L. M. S., & Olsson, B. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2534 · Cited by 73 · see citing works
Effect of calorie restriction on the free-living physical activity levels of nonobese humans: results of three randomized trials
Martin, C. K., Das, S. K., Lindblad, L., Racette, S. B., McCrory, M. A., Weiss, E. P., DeLany, J. P., Kraus, W. E., & for the CALERIE Study Team (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00846.2009 · Cited by 73 · see citing works
Corrective responses in human food intake identified from an analysis of 7-d food-intake records
Bray, G. A., Flatt, J.-P., Volaufova, J., DeLany, J. P., & Champagne, C. M. (2008) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26289 · Cited by 72 · cited 1× · see citing works
“However, signals related to energy depletion may be stronger than those from excess energy stores [31].”
Background
High energy expenditure masks low physical activity in obesity
DeLany, J. P., Kelley, D. E., Hames, K. C., Jakicic, J. M., & Goodpaster, B. H. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.172 · Cited by 71 · see citing works
Associations of leptin, insulin resistance and thyroid function with long‐term weight loss in dieting obese men
Näslund, E. B., Andersson, I., Degerblad, M., Kogner, P., Kral, J. G., Rössner, S., & Hellström, P. M. (2000) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2000.00737.x · Cited by 71 · see citing works
Periconceptional nutrition and the early programming of a life of obesity or adversity
Zhang, S., Rattanatray, L., McMillen, I. C., Suter, C. M., & Morrison, J. L. (2010) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2010.12.004 · Cited by 61 · see citing works
Does metabolic compensation explain the majority of less-than-expected weight loss in obese adults during a short-term severe diet and exercise intervention?
Byrne, N. M., Wood, R. E., Schutz, Y., & Hills, A. P. (2012) · International Journal of Obesity · doi:10.1038/ijo.2012.109 · Cited by 56 · see citing works
Self-citation
Calories from Soft Drinks — Do They Matter?
Caprio, S. (2012) · New England Journal of Medicine · doi:10.1056/nejme1209884 · Cited by 53 · see citing works
Influence of Changes in Body Composition and Adaptive Thermogenesis on the Difference between Measured and Predicted Weight Loss in Obese Women
Goele, K., Bosy‐Westphal, A., Rümcker, B., Lagerpusch, M., & ller, M. J. M. U. (2009) · Obesity Facts · doi:10.1159/000210369 · Cited by 46 · see citing works
Metabolic adaptation and energy requirements in developing countries.
James, W. P. T., & Shetty, P. S. (1982) · PubMed · Cited by 44 · see citing works
The magnitude of the energy imbalance in obesity is generally underestimated
Bouchard, C. (2008) · International Journal of Obesity · doi:10.1038/sj.ijo.0803796 · Cited by 43 · see citing works
The effect of pegylated human recombinant leptin (PEG-OB) on neuroendocrine adaptations to semi-starvation in overweight men
Hukshorn, C. J., Menheere, P. P. C. A., Westerterp‐Plantenga, M. S., & Saris, W. H. M. (2003) · European Journal of Endocrinology · doi:10.1530/eje.0.1480649 · Cited by 39 · see citing works
Growth, thermogenesis, and hyperphagia
ALPERT, S. (1990) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/52.5.784 · Cited by 36 · see citing works
Non Linear Weight Gain with Long Term Overfeeding in Man
Dériaz, O., Tremblay, A., & Bouchard, C. (1993) · Obesity Research · doi:10.1002/j.1550-8528.1993.tb00609.x · Cited by 35 · see citing works
Heifer nutrient intake during early- and mid-gestation programs adult offspring adiposity and mRNA expression of growth-related genes in adipose depots
Micke, G. C., Sullivan, T. M., McMillen, I. C., Gentili, S., & Perry, V. E. A. (2011) · Reproduction · doi:10.1530/rep-10-0332 · Cited by 34 · see citing works
A two-reservoir energy model of the human body
Alpert, S. (1979) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/32.8.1710 · Cited by 34 · see citing works
A rapidly occurring compensatory decrease in physical activity counteracts diet-induced weight loss in female monkeys
Sullivan, E. L., & Cameron, J. L. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00617.2009 · Cited by 33 · see citing works
Are defects in energy expenditure involved in the causation of obesity?
Prentice, A. M. (2007) · Obesity Reviews · doi:10.1111/j.1467-789x.2007.00325.x · Cited by 27 · see citing works
An evolutionary perspective on the trans-generational basis of obesity
Wells, J. C. K. (2011) · Annals of Human Biology · doi:10.3109/03014460.2011.580781 · Cited by 25 · see citing works
Factors Predicting Individual Variability in Diet‐Induced Weight Loss in MF1 Mice
Vaanholt, L. M., Magee, V., & Speakman, J. R. (2011) · Obesity · doi:10.1038/oby.2011.279 · Cited by 18 · see citing works
Physical Activity and the Risk of Becoming Overweight or Obese in Middle‐Aged and Older Women
Britton, K. A., Lee, I., Wang, L., et al. (2011) · Obesity · doi:10.1038/oby.2011.359 · Cited by 17 · see citing works
Luxuskonsumption ‐ Myth or Reality?
Bray, G. A. (1995) · Obesity Research · doi:10.1002/j.1550-8528.1995.tb00180.x · Cited by 13 · see citing works
The biology of energy expenditure
Suarez, R. K. (2010) · Journal of Experimental Biology · doi:10.1242/jeb.053835 · Cited by 11 · see citing works
Comment on the paper by Gibala, Little, Macdonald and Hawley entitled Physiological adaptations to low‐volume, high‐intensity interval training in health and disease
Gayda, M., Juneau, M., & Nigam, A. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.232652 · Cited by 5 · see citing works
Central regulation of food intake and energy expenditure
Heal, D. J., Smith, S. L., & Jones, R. B. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.05.002 · Cited by 5 · see citing works
Energy Substrate Partitioning and Efficiency in Individuals With Atherogenic Lipoprotein Phenotype
Faghihnia, N., Siri‐Tarino, P. W., Krauss, R. M., & Brooks, G. A. (2011) · Obesity · doi:10.1038/oby.2011.72 · Cited by 4 · see citing works

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Research works printed but not linked: 1

[12]12. Harrold JA, Dovey TM, Blundell JE, Halford JCG. CNS regula- tion of appetite. Neuropharmacology. 2012;63(1):3-17.

Sorted by citations

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Self-citation
Metabolic Adaptations to Weight Loss: A Brief Review
Martínez-Gómez, M. G., & Roberts, B. M. (2022) · Journal of Strength & Conditioning Research · doi:10.1519/jsc.0000000000003991 · Cited by 32 · see citing works

Early Weight Gain Related to Later Weight Gain in Adolescents on Depot Medroxyprogesterone Acetate
Bonny, A. E., Secic, M., & Cromer, B. A. (2011) · Obstetrics and Gynecology · doi:10.1097/aog.0b013e31820f387c · Cited by 65 · see citing works
Correlation analysis of gestational weight gain and dietary nutrition and the knowledge of weight gain in pregnant women
Xu, Y. Y., & Zhang, Z. (2010) · Zhonghua xiandai huli zazhi · doi:10.3760/cma.j.issn.1674-2907.2010.34.012
Characterization of olanzapine-induced weight gain in rats
Goudie, A. J., Smith, J. A., & Halford, J. C. G. (2002) · Journal of Psychopharmacology · doi:10.1177/026988110201600402 · Cited by 102 · see citing works
Willingness of female smokers to tolerate postcessation weight gain
Pomerleau, C. S., & Kurth, C. L. (1996) · Journal of Substance Abuse · doi:10.1016/s0899-3289(96)90215-1 · Cited by 76 · see citing works
The characteristics of women smokers concerned about postcessation weight gain
Levine, M. D., Perkins, K. A., & Marcus, M. D. (2001) · Addictive Behaviors · doi:10.1016/s0306-4603(00)00156-8 · Cited by 75 · see citing works

Authors: Byrne, N. M., & Hills, A. P.
Affiliations: Queensland University of Technology (AU)
Griffith University (AU)
Corresponding author: Byrne, Nuala M.
ORCID: Byrne, Nuala M.
Hills, Andrew P.
Venue: Current Obesity Reports
Publisher: Springer Science and Business Media LLC
Published: 2013-01-09
Volume: 2
Issue: 1
Pages: 65-76
ISSN: 2162-4968 (ISSN-L)
DOI: 10.1007/s13679-012-0040-9
OpenAlex: W2039553332
Cited by: 13
References: 99
Citations by year: 2026: 1 · 2025: 2 · 2023: 2 · 2021: 1 · 2019: 1 · 2018: 2 · 2017: 2 · 2015: 1 · 2013: 1
FWCI: 0.36
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: Current Obesity Reports (publishedVersion)
QUT ePrints (Queensland University of Technology) (submittedVersion)
eCite Digital Repository (University of Tasmania) (submittedVersion)
Figshare (submittedVersion, cc-by)
Griffith Research Online (submittedVersion)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
Keywords: obesity, weight gain, energy intake, energy expenditure, energy balance, obesogenic environment, behavioral factors

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