Cited by 517Sleep and Work-Related FatigueCircadian rhythm and melatoninSleep and related disorders

The DOI matches its Crossref record; 112 of the 114 references it cites were found in a registry or an index; none of the 67 sources its claims cite is checked for support yet.

Shift Work: Disrupted Circadian Rhythms and Sleep—Implications for Health and Well-being

Open access
James, Stephen M., Honn, Kimberly A., Gaddameedhi, Shobhan, Van Dongen, Hans P.A.·2017·Current Sleep Medicine Reports

Abstract

Purpose of review Our 24/7 society is dependent on shift work, despite mounting evidence for negative health outcomes from sleep displacement due to shift work. This paper reviews short- and long-term health consequences of sleep displacement and circadian misalignment due to shift work.Recent findings We focus on four broad health domains: metabolic health; risk of cancer; cardiovascular health; and mental health. Circadian misalignment affects these domains by inducing sleep deficiency, sympathovagal and hormonal imbalance, inflammation, impaired glucose metabolism, and dysregulated cell cycles. This leads to a range of medical conditions, including obesity, metabolic syndrome, type II diabetes, gastrointestinal dysfunction, compromised immune function, cardiovascular disease, excessive sleepiness, mood and social disorders, and increased cancer risk.Summary Interactions of biological disturbances with behavioral and societal factors shape the effects of shift work on health and well-being. Research is needed to better understand the underlying mechanisms and drive the development of countermeasures.

Overview

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Crossref · 10.1007/s40675-017-0071-6

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  • It may state two separate claims as one. 15
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  • The paper relies on this without support.

    Animal models with environmentally disturbed circadian systems are informative for human shift work cancer risk.

    “Findings in animal models with environmentally disturbed circadian systems (simulated shift work) indicate that circadian disruption increases the progression of cancer, possibly through dysregulation of the cell cycle, accumulation of DNA damage, and reduced tumor suppression [49,50,51,52].”
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Metadata

Authors
James, S. M., Honn, K. A., Gaddameedhi, S., & Van Dongen, H. P. A.
Affiliations
Washington State University Spokane (US)
Venue
Current Sleep Medicine Reports
Published
2017-04-27
Volume
3
Issue
2
Pages
104-112
ISSN
2198-6401 (ISSN-L)
OpenAlex
W2607662745
Cited by
517
References
114
Citations by year
2026: 53 · 2025: 94 · 2024: 80 · 2023: 50 · 2022: 73 · 2021: 79 · 2020: 45 · 2019: 23 · 2018: 17 · 2017: 3
FWCI
31.11
Type
journal article
Language
en
Open access
Locations
  • Current Sleep Medicine Reports (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Heart, Lung, and Blood Institute (R01HL124211)
  • National Institute of Environmental Health Sciences (R00ES022640)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Keywords
shift work, circadian misalignment, insufficient sleep, metabolic health, cancer risk, cardiovascular disease, mental health, obesity, metabolic syndrome, type 2 diabetes, inflammation, glucose metabolism, immune function, excessive sleepiness, well-being

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