Cited by 1,110Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

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Rat hippocampal neurons in dispersed cell culture.

Banker, Gary A., Cowan, W. Maxwell·1977·Brain Research

DOI 10.1016/0006-8993(77)90594-7

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Abstract

An in vitro system has been developed for the study of isolated hippocampal neurons from 18- or 19-day rat fetuses. Following trypsinization the cells are plated out at low density on polylysine-treated coverslips in an enriched medium. The isolated neurons rapidly attach to the substrate and initiate process extension. Little reaggregation occurs and the number of non-neuronal cells present is minimal. Unless co-cultured with tissue explants the neurons survive for only a few days; in the presence of hippocampal explants the initial growth of the isolated cells is improved and their survival in culture is extended to about two weeks. Some of the cells in such cultures develop a characteristic branching pattern closely resembling that of maturing hippocampal pyramidal cells in vivo. There is a clear relationship between the stage of the cells' development and their growth in culture. Cells which had completed DNA synthesis about 48 h before dissociation, and which were in the process of migration to the cortical plate, survived best in our cultures. Early post-mitotic cells which were still within the ventricular zone and cells which had already reached the cortical plate grew poorly. This system should permit the study not only of process formation by these cells, but also of their capacity to form specific synapses in vitro and of the biochemical constituents of their surfaces.

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Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system.
de Nó, R. L. (1934) · Cited by 1,974
The autoradiographic demonstration of axonal connections in the central nervous system
Cowan, W. M., Gottlieb, D. I., Hendrickson, A. E., Price, J. L., & Woolsey, T. A. (1972) · Brain Research · doi:10.1016/0006-8993(72)90344-7 · Cited by 1,610
Self-citation
An autoradiographic study of the time of origin and the pattern of granule cell migration in the dentate gyrus of the rat
Schlessinger, A. R., Cowan, W. M., & Gottlieb, D. I. (1975) · The Journal of Comparative Neurology · doi:10.1002/cne.901590202 · Cited by 731
Self-citation
ATTACHMENT AND CULTURE OF DISSOCIATED CELLS FROM RAT EMBRYO CEREBRAL HEMISPHERES ON POLYLYSINE-COATED SURFACE
Yavin, E., & Yavin, Z. (1974) · The Journal of Cell Biology · doi:10.1083/jcb.62.2.540 · Cited by 470
Synapse formation between dissociated nerve and muscle cells in low density cell cultures
Fischbach, G. D. (1972) · Developmental Biology · doi:10.1016/0012-1606(72)90023-1 · Cited by 458
FINE STRUCTURE OF NERVE FIBERS AND GROWTH CONES OF ISOLATED SYMPATHETIC NEURONS IN CULTURE
Bunge, M. (1973) · Journal of Cell Biology · doi:10.1083/jcb.56.3.713 · Cited by 452
Possible roles for cell-to-substratum adhesion in neuronal morphogenesis
Letourneau, P. C. (1975) · Developmental Biology · doi:10.1016/0012-1606(75)90378-4 · Cited by 444
PRIMARY CULTURES OF DISSOCIATED SYMPATHETIC NEURONS
Mains, R. E., & Patterson, P. H. (1973) · The Journal of Cell Biology · doi:10.1083/jcb.59.2.329 · Cited by 425
Surface Movements during the Growth of Single Explanted Neurons
Bray, D. (1970) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.65.4.905 · Cited by 372
A SILVER METHOD FOR PARAFFIN SECTIONS OF NEURAL TISSUE>
SEVIER, A. C., & Munger, B. L. (1965) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-196501000-00012 · Cited by 354

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Self-citation
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Self-citation
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Self-citation
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Self-citation
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Time-restricted role for dendritic activation of the mTOR-p70S6K pathway in the induction of late-phase long-term potentiation in the CA1
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Juhaszova, M., & Blaustein, M. P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.5.1800 · Cited by 296
KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport.
Yamazaki, H., Nakata, T., Okada, Y., & Hirokawa, N. (1995) · The Journal of Cell Biology · doi:10.1083/jcb.130.6.1387 · Cited by 293
Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis.
Cameron, P. L., Südhof, T. C., Jahn, R., & Camilli, P. V. D. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.115.1.151 · Cited by 293
Syntaxin 13 Mediates Cycling of Plasma Membrane Proteins via Tubulovesicular Recycling Endosomes
Prekeris, R., Klumperman, J., Chen, Y. A., & Scheller, R. H. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.143.4.957 · Cited by 286
Functional Properties of Channels Formed by the Neuronal Gap Junction Protein Connexin36
Srinivas, M., Rozental, R., Kojima, T., Dermietzel, R., Mehler, M., Condorelli, D. F., Kessler, J. A., & Spray, D. C. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-22-09848.1999 · Cited by 290
Major Histocompatibility Complex (MHC) Class I Gene Expression in Single Neurons of the Central Nervous System: Differential Regulation by Interferon (IFN)-γ and Tumor Necrosis Factor (TNF)-α
Neumann, H., Schmidt, H., Cavalié, A., Jenne, D. E., & Wekerle, H. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.2.305 · Cited by 287
A Novel Targeting Signal for Proximal Clustering of the Kv2.1 K+ Channel in Hippocampal Neurons
Seung Taik, L. I. M., Antonucci-Durgan, D. E., Scannevin, R. H., & Trimmer, J. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)80902-2 · Cited by 288
TGF-β Signaling Specifies Axons during Brain Development
Yi, J. J., Barnes, A. P., Hand, R., Polleux, F., & Ehlers, M. D. (2010) · Cell · doi:10.1016/j.cell.2010.06.010 · Cited by 284
Activation of Silent Synapses by Rapid Activity-Dependent Synaptic Recruitment of AMPA Receptors
Liao, D., Scannevin, R. H., & Huganir, R. L. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-16-06008.2001 · Cited by 288
Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion
Haass, C., Hung, A. Y., & Selkoe, D. J. (1991) · Journal of Neuroscience · doi:10.1523/jneurosci.11-12-03783.1991 · Cited by 282
Intact sorting, targeting, and clustering of γ‐aminobutyric acid A receptor subtypes in hippocampal neurons in vitro
Brünig, I., Scotti, E., Sidler, C., & Fritschy, J. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.10102 · Cited by 278
J1/tenascin in substrate-bound and soluble form displays contrary effects on neurite outgrowth.
Lochter, A., Vaughan, L., Kaplony, A., Prochiantz, A., Schachner, M., & Faissner, A. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.113.5.1159 · Cited by 275
Seven Novel Mammalian SNARE Proteins Localize to Distinct Membrane Compartments
Advani, R. J., Bae, H.-R., Bock, J. B., Chao, D. S., Doung, Y.-C., Prekeris, R., Yoo, J.-S., & Scheller, R. H. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.17.10317 · Cited by 263
SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons
Rumbaugh, G., Adams, J. P., Kim, J. H., & Huganir, R. L. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600084103 · Cited by 260
Differential spatiotemporal expression of K+ channel polypeptides in rat hippocampal neurons developing in situ and in vitro
Maletić‐Savatić, M., Lenn, N., & Trimmer, J. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-05-03840.1995 · Cited by 260
Interaction of the Postsynaptic Density-95/Guanylate Kinase Domain-Associated Protein Complex with a Light Chain of Myosin-V and Dynein
Naisbitt, S. R., Valtschanoff, J. G., Allison, D. W., Sala, C., Kim, E., Craig, A. M., Weinberg, R. J., & Sheng, M. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-12-04524.2000 · Cited by 259
Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival
Brundin, P., Ole Isacson, A., & Björklund, A. (1985) · Brain Research · doi:10.1016/0006-8993(85)91550-1 · Cited by 259
ICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granules.
Solimena, M., Dirkx, R. A., Hermel, J., Pleasic‐Williams, S., Shapiro, J., Caron, L. A., & Rabin, D. U. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00564.x · Cited by 256
Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra
Björklund, A., Schmidt, R. H., & Stenevi, U. (1980) · Cell and Tissue Research · doi:10.1007/bf00234031 · Cited by 255
Acute Impairment of Mitochondrial Trafficking by β-Amyloid Peptides in Hippocampal Neurons
Rui, Y., Tiwari, P., Xie, Z., & Zheng, J. Q. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3231-06.2006 · Cited by 255
A Fundamental Role for KChIPs in Determining the Molecular Properties and Trafficking of Kv4.2 Potassium Channels
Shibata, R., Misonou, H., Campomanes, C. R., Anderson, A. E., Schrader, L. A., Doliveira, L. C., Carroll, K. I., Sweatt, J. D., Rhodes, K. J., & Trimmer, J. S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306142200 · Cited by 253
Developmental neurotoxicity testing in vitro: Models for assessing chemical effects on neurite outgrowth
Radio, N. M., & Mundy, W. R. (2008) · NeuroToxicology · doi:10.1016/j.neuro.2008.02.011 · Cited by 258
Developmental vitamin D deficiency causes abnormal brain development
Eyles, D. W., Feron, F. P., Cui, X., Kesby, J. P., Harms, L. R., Ko, P., McGrath, J. J., & Burne, T. H. J. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.04.015 · Cited by 248

Authors: Banker, G. A., & Cowan, W. M.
Affiliations: Washington University in St. Louis (US)
ORCID: Banker, Gary A.
Venue: Brain Research
Publisher: Elsevier BV
Published: 1977-05
Volume: 126
Issue: 3
Pages: 397-425
ISSN: 0006-8993 (ISSN-L)
DOI: 10.1016/0006-8993(77)90594-7
OpenAlex: W1987700551
Cited by: 1,110
References: 28
Citations by year: 2026: 6 · 2025: 12 · 2024: 7 · 2023: 10 · 2022: 14 · 2021: 18 · 2020: 23 · 2019: 20 · 2018: 24 · 2017: 16 · 2016: 21 · 2015: 24 · 2014: 34 · 2013: 19 · 2012: 26
FWCI: 3.72
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Brain Research (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords: hippocampal neurons, neuronal isolation, neuronal survival, cortical plate, ventricular zone, neuronal migration, DNA synthesis, synaptogenesis
MeSH terms: Animals, Axons, Cell Aggregation, Cell Division, Cell Movement, Cell Survival, Cells, Cultured, Hippocampus, Neurons, Rats

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Rat hippocampal neurons in dispersed cell culture.

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