Cited by 192Neuroscience and Neuropharmacology ResearchMemory and Neural MechanismsNicotinic Acetylcholine Receptors Study

The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

Cholinergic stimulation enhances long-term potentiation in the CA1 region of rat hippocampus

Blitzer, Robert D., Gil, Orlando, Landau, Emmanuel M.·1990·Neuroscience Letters

DOI 10.1016/0304-3940(90)90835-w

Open this paper in CoChat — free account

Abstract

The effect of the cholinergic agonist carbachol on a putative substrate for memory (long-term potentiation; LTP) was investigated in slices of rat hippocampus (CA1 region). Carbachol (5 microM) increased LTP when the presynaptic depression of the EPSP was controlled. The results indicate that carbachol enhances the effectiveness of the tetanus, probably through postsynaptic mechanisms. This effect may have implications for the role of acetylcholine in memory and the use of cholinergics in memory disorders.

Integrity signals

Registry

Crossref · 10.1016/0304-3940(90)90835-w

Cites

23 of 23 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The cholinergic hypothesis of geriatric memory dysfunction
Bartus, R. T., Dean, R. L., Beer, B., & Lippa, A. S. (1982) · Science · doi:10.1126/science.7046051 · Cited by 5,545
Magnesium gates glutamate-activated channels in mouse central neurones
Nowak, L. M., Bregestovski, P. D., Ascher, P., Herbet, A., & Prochiantz, A. (1984) · Nature · doi:10.1038/307462a0 · Cited by 4,116
Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
Morris, R. G. M., Anderson, E., Lynch, G. S., & Baudry, M. (1986) · Nature · doi:10.1038/319774a0 · Cited by 3,640
Psychopharmacology: The third generation of progress
O’Connell, R. A. (1988) · Comprehensive Psychiatry · doi:10.1016/0010-440x(88)90057-0 · Cited by 3,020
Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones
Mayer, M. L., Westbrook, G. L., & Guthrie, P. B. (1984) · Nature · doi:10.1038/309261a0 · Cited by 2,941
Intracellular injections of EGTA block induction of hippocampal long-term potentiation
Lynch, G., Larson, J., Kelso, S., Barrionuevo, G., & Schottler, F. (1983) · Nature · doi:10.1038/305719a0 · Cited by 1,116
Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic Transmission
Malenka, R. C., Kauer, J. A., Zucker, R. S., & Nicoll, R. A. (1988) · Science · doi:10.1126/science.2845577 · Cited by 829
Synaptic enhancement in fascia dentata: Cooperativity among coactive afferents
McNaughton, B. L., Douglas, R. M., & Goddard, G. V. (1978) · Brain Research · doi:10.1016/0006-8993(78)90030-6 · Cited by 647
Long-term potentiation in the hippocampus using depolarizing current pulses as the conditioning stimulus to single volley synaptic potentials
Gustafsson, B., Wigstrom, H., Abraham, W., & Huang, Y. (1987) · The Journal of Neuroscience · doi:10.1523/jneurosci.07-03-00774.1987 · Cited by 583
Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl d-aspartate antagonists
Harris, E. W., & Cotman, C. W. (1986) · Neuroscience Letters · doi:10.1016/0304-3940(86)90451-9 · Cited by 540

Show all 23 references

Sorted by citations

The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease
Hampel, H., Mesulam, M.-M., Cuello, A. C., Farlow, M. R., Giacobini, E., Grossberg, G. T., Khachaturian, A. S., Vergallo, A., Cavedo, E., Snyder, P. J., et al. (2018) · Brain · doi:10.1093/brain/awy132 · Cited by 1,918
Modes and models of forebrain cholinergic neuromodulation of cognition
Hasselmo, M. E., & Sarter, M. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.104 · Cited by 733
Neuromodulation and cortical function: modeling the physiological basis of behavior
Hasselmo, M. E. (1995) · Behavioural Brain Research · doi:10.1016/0166-4328(94)00113-t · Cited by 557
High acetylcholine levels set circuit dynamics for attention and encoding and low acetylcholine levels set dynamics for consolidation
Hasselmo, M. E., & McGaughy, J. (2004) · Progress in Brain Research · doi:10.1016/s0079-6123(03)45015-2 · Cited by 525
Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: computational modeling and brain slice physiology
Hasselmo, M., & Schnell, E. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-06-03898.1994 · Cited by 466
Neurobiological after-effects of non-invasive brain stimulation
Cirillo, G., Di Pino, G., Capone, F., Ranieri, F., Florio, L., Todisco, V., Tedeschi, G., Funke, K., & Di Lazzaro, V. (2017) · Brain Stimulation · doi:10.1016/j.brs.2016.11.009 · Cited by 446
Acetylcholine and memory
Hasselmo, M. E., & Bower, J. M. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90159-j · Cited by 429
Expression of m1-m4 muscarinic acetylcholine receptor proteins in rat hippocampus and regulation by cholinergic innervation
Levey, A. I., Edmunds, S. M., Koliatsos, V. E., Wiley, R. G., & Heilman, C. J. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-05-04077.1995 · Cited by 421
Encoding and retrieval of episodic memories: Role of cholinergic and GABAergic modulation in the hippocampus
Hasselmo, M. E., Wyble, B., & Wallenstein, G. V. (1998) · Hippocampus · doi:10.1002/(sici)1098-1063(1996)6:6 · Cited by 366
Free recall and recognition in a network model of the hippocampus: simulating effects of scopolamine on human memory function
Hasselmo, M. E., & Wyble, B. (1997) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)00048-x · Cited by 338
Modulation of long-term synaptic depression in visual cortex by acetylcholine and norepinephrine
Kirkwood, A., Rozas, C., Kirkwood, J., Perez, F., & Bear, M. F. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-05-01599.1999 · Cited by 315
alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability
Castro, N. G., & Albuquerque, E. X. (1995) · Biophysical Journal · doi:10.1016/s0006-3495(95)80213-4 · Cited by 273
The role of acetylcholine in cortical synaptic plasticity
Rasmusson, D. D. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00259-x · Cited by 269
Muscarinic cholinergic influences in memory consolidation
Power, A. (2003) · Neurobiology of Learning and Memory · doi:10.1016/s1074-7427(03)00086-8 · Cited by 261
Muscarinic acetylcholine receptors in the hippocampus, neocortex and amygdala: a review of immunocytochemical localization in relation to learning and memory
van der Zee, E. A., & Luiten, P. G. M. (1999) · Progress in Neurobiology · doi:10.1016/s0301-0082(98)00092-6 · Cited by 261
The cholinergic system and hippocampal plasticity
Drever, B. D., Riedel, G., & Platt, B. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.11.037 · Cited by 240
Cholinergic modulation of activity-dependent synaptic plasticity in the piriform cortex and associative memory function in a network biophysical simulation
Hasselmo, M. E., & Barkai, E. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-10-06592.1995 · Cited by 215
Focusing Effect of Acetylcholine on Neuroplasticity in the Human Motor Cortex
Kuo, M., Grosch, J., Fregni, F., Paulus, W., & Nitsche, M. A. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4104-07.2007 · Cited by 212
Specific basal forebrain-cortical cholinergic circuits coordinate cognitive operations
Záborszky, L., Gombkoto, P., Varsanyi, P., Gielow, M. R., Poe, G., Role, L. W., Ananth, M., Rajebhosale, P., Talmage, D. A., Hasselmo, M. E., et al. (2018) · The Journal of Neuroscience · doi:10.1523/jneurosci.1676-18.2018 · Cited by 202
The pharmacology of neuroplasticity induced by non‐invasive brain stimulation: building models for the clinical use of CNS active drugs
Nitsche, M. A., Müller‐Dahlhaus, F., Paulus, W., & Ziemann, U. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.232975 · Cited by 207
Changes in Acetylcholine Extracellular Levels During Cognitive Processes: Table 1.Preprint
Pepeu, G., & Giovannini, M. G. (2004) · Learning & Memory · doi:10.1101/lm.68104 · Cited by 193
Cholinergic modulation of cognitive processing: insights drawn from computational models
Newman, E. L., Gupta, K., Climer, J. R., Monaghan, C. K., & Hasselmo, M. E. (2012) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2012.00024 · Cited by 197
NGF Is Essential for Hippocampal Plasticity and Learning
Conner, J. M., Franks, K. M., Titterness, A. K., Russell, K., Merrill, D. A., Christie, B. R., Sejnowski, T. J., & Tuszynski, M. H. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.2594-09.2009 · Cited by 189
The Biology and Pathobiology of Glutamatergic, Cholinergic, and Dopaminergic Signaling in the Aging Brain
Gąsiorowska, A., Wydrych, M., Drapich, P., Zadrożny, M., Steczkowska, M., Niewiadomski, W., & Niewiadomska, G. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.654931 · Cited by 199
Cholinergic Inhibition of Neocortical Pyramidal Neurons
Gulledge, A. T., & Stuart, G. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2697-05.2005 · Cited by 188
Prenatal Dietary Choline Supplementation Decreases the Threshold for Induction of Long-Term Potentiation in Young Adult Rats
Pyapali, G. K., Turner, D. A., Williams, C. L., Meck, W. H., & Swartzwelder, H. S. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.79.4.1790 · Cited by 170
Muscarinic receptors mediating depression and long‐term potentiation in rat hippocampus.
Auerbach, J. M., & Segal, M. (1996) · The Journal of Physiology · doi:10.1113/jphysiol.1996.sp021323 · Cited by 168
Long-Term Potentiation at CA3–CA1 Hippocampal Synapses with Special Emphasis on Aging, Disease, and Stress
Kumar, A. (2011) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2011.00007 · Cited by 175
Blockade of Central Cholinergic Receptors Impairs New Learning and Increases Proactive Interference in a Word Paired-Associate Memory Task.
Atri, A., Sherman, S. J., Norman, K. A., Kirchhoff, B. A., Nicolas, M. M., Greicius, M. D., Cramer, S. C., Breiter, H. C., Hasselmo, M. E., & Stern, C. E. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.1.223 · Cited by 168
Muscarinic Modulation of Spike Backpropagation in the Apical Dendrites of Hippocampal CA1 Pyramidal Neurons
Tsubokawa, H., & Ross, W. N. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-15-05782.1997 · Cited by 157
What do grid cells contribute to place cell firing?
Bush, D., Barry, C., & Burgess, N. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2013.12.003 · Cited by 170
Coactivation of β-Adrenergic and Cholinergic Receptors Enhances the Induction of Long-Term Potentiation and Synergistically Activates Mitogen-Activated Protein Kinase in the Hippocampal CA1 Region
Watabe, A. M., Zaki, P. A., & O’Dell, T. J. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-16-05924.2000 · Cited by 146
Mode shifting between storage and recall based on novelty detection in oscillating hippocampal circuits
Meeter, M., Murre, J. M. J., & Talamini, L. M. (2004) · Hippocampus · doi:10.1002/hipo.10214 · Cited by 146
Cholinergic Blockade Reduces Theta-Gamma Phase Amplitude Coupling and Speed Modulation of Theta Frequency Consistent with Behavioral Effects on Encoding
Newman, E. L., Gillet, S. N., Climer, J. R., & Hasselmo, M. E. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2586-13.2013 · Cited by 140
Cholinergic Activity Enhances Hippocampal Long-Term Potentiation in CA1 during Walking in Rats
Leung, L.-W. S., Bixia Shen, A., Rajakumar, N., & Ma, J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-28-09297.2003 · Cited by 130
Septal cholinergic afferents regulate expression of brain-derived neurotrophic factor andβ-nerve growth factor mRNA in rat hippocampus
Lindefors, N., Ernfors, P., Falkenberg, T., & Persson, H. (1992) · Experimental Brain Research · doi:10.1007/bf02259130 · Cited by 124
Augmentation of locomotor activity by chronic phencyclidine is associated with an increase in striatal NMDA receptor function and an upregulation of the NR1 receptor subunit
Hanania, T., Hillman, G. R., & Johnson, K. M. (1999) · Synapse · doi:10.1002/(sici)1098-2396(19990301)31:3 · Cited by 46
Molecular Mechanisms of Long-Term Potentiation in the Insular CortexIn Vivo
Jones, M. W., French, P. J., Bliss, T. V. P., & Rosenblum, K. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-21-j0002.1999 · Cited by 121
Enhancement of Associative Long-Term Potentiation by Activation of β-Adrenergic Receptors at CA1 Synapses in Rat Hippocampal Slices
Lin, Y., Min, M., Chiu, T., & Yang, H. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-10-04173.2003 · Cited by 116
Muscarinic receptors involved in hippocampal plasticity
Segal, M., & Auerbach, J. M. (1997) · Life Sciences · doi:10.1016/s0024-3205(97)00051-9 · Cited by 107
Dopamine D1-deficient mutant mice do not express the late phase of hippocampal long-term potentiation
Matthies, H., Becker, A., Schröeder, H., Kraus, J., Höllt, V., & Krug, M. (1997) · Neuroreport · doi:10.1097/00001756-199711100-00023 · Cited by 106
Evidence for Involvement of Central 5-HT4 Receptors in Cholinergic Function Associated with Cognitive Processes: Behavioral, Electrophysiological, and Neurochemical Studies
Matsumoto, M., Togashi, H., Mori, K., Ueno, K.-I., Ohashi, S., Kojima, T., & Yoshioka, M. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38802-0 · Cited by 104
M1 Muscarinic Acetylcholine Receptors Activate Extracellular Signal-Regulated Kinase in CA1 Pyramidal Neurons in Mouse Hippocampal Slices
Berkeley, J. L., Gomeza, J., Wess, J., Hamilton, S. E., Nathanson, N. M., & Levey, A. I. (2001) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2001.1042 · Cited by 98
Neuroprotective effect of anthocyanins on acetylcholinesterase activity and attenuation of scopolamine‐induced amnesia in rats
Gutierres, J. M., Carvalho, F. B., Schetinger, M. R. C., Agostinho, P. M., Marisco, P. C., Vieira, J. M., da Rosa, M. M., Bohnert, C., Rubin, M. A., Morsch, V. M., et al. (2013) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2013.12.006 · Cited by 97
New perspectives on the basal forebrain cholinergic system in Alzheimer’s disease
Berry, A. S., & Harrison, T. M. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105192 · Cited by 102
A specific role for septohippocampal acetylcholine in memory?
Easton, A., Douchamps, V., Eacott, M. J., & Lever, C. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.07.022 · Cited by 106
Focused ultrasound-induced blood-brain barrier opening improves adult hippocampal neurogenesis and cognitive function in a cholinergic degeneration dementia rat model
Shin, J., Kong, C., Lee, J., Choi, B. Y., Sim, J., Koh, C. S., Park, M., Na, Y. C., Suh, S. W., Chang, W. S., et al. (2019) · Alzheimer s Research & Therapy · doi:10.1186/s13195-019-0569-x · Cited by 93
Cholinergic input uncouples Ca2+ changes from K+ conductance activation and amplifies intradendritic Ca2+ changes in hippocampal neurons
Müller, W. S., & Connor, J. A. (1991) · Neuron · doi:10.1016/0896-6273(91)90230-w · Cited by 92
Cholinergic Agonist Carbachol Enables Associative Long-Term Potentiation in Piriform Cortex Slices
Patil, M. M., Linster, C., Lubenov, E., & Hasselmo, M. E. (1998) · Journal of Neurophysiology · doi:10.1152/jn.1998.80.5.2467 · Cited by 91
Activation of muscarinic receptors induces protein synthesis‐dependent long‐lasting depression in the perirhinal cortex
Massey, P. V., Bhabra, G., Cho, K., Brown, M. W., & Bashir, Z. I. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01631.x · Cited by 90
Histaminergic modulation of synaptic plasticity in area CA1 of rat hippocampal slices
Brown, R. E., Fedorov, N. B., Haas, H. I., & Reymann, K. (1995) · Neuropharmacology · doi:10.1016/0028-3908(94)00138-i · Cited by 92
Endocannabinoids restrict hippocampal long-term potentiation via CB1
Slanina, K. A., Roberto, M., & Schweitzer, P. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.04.021 · Cited by 89
Possible role of acetylcholine in regulating spatial novelty effects on theta rhythm and grid cells
Barry, C., Heys, J. G., & Hasselmo, M. E. (2012) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00005 · Cited by 81
Hippocampal representations as a function of time, subregion, and brain state
Duncan, K. D., & Schlichting, M. L. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.03.006 · Cited by 86
Bacopa monnieri ameliorates memory deficits in olfactory bulbectomized mice: Possible involvement of glutamatergic and cholinergic systems
Le, X. T., Pham, H. T. N., Do, P. T., Fujiwara, H., Tanaka, K., Li, F., Van Nguyen, T., Nguyen, K. M., & Matsumoto, K. (2013) · Neurochemical Research · doi:10.1007/s11064-013-1129-6 · Cited by 79
Acetylcholine and the complex interdependence of memory and attention
Decker, A. L., & Duncan, K. D. (2020) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2020.01.013 · Cited by 85
The ascending neuromodulatory systems in learning by reinforcement: comparing computational conjectures with experimental findings
Pennartz, C. M. A. (1995) · Brain Research Reviews · doi:10.1016/0165-0173(95)00014-3 · Cited by 73
Memory processes during sleep: beyond the standard consolidation theory
Axmacher, N., Draguhn, A., Elger, C. E., & Fell, J. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0019-1 · Cited by 80
Low-frequency trains of paired stimuli induce long-term depression in area CA1 but not in dentate gyrus of the intact rat
Doy�re, V., Errington, M. L., Laroche, S., & Bliss, T. V. P. (1996) · Hippocampus · doi:10.1002/(sici)1098-1063(1996)6:1 · Cited by 79
Cholinergic afferents to the locus coeruleus and noradrenergic afferents to the medial septum mediate LTP-reinforcement in the dentate gyrus by stimulation of the amygdala
Bergado, J. A., Frey, S., Lopez‐Rojas, J., Almaguer‐Melian, W., & Frey, J. U. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2007.05.003 · Cited by 66
Distribution of m1 muscarinic acetylcholine receptors in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies—an immunohistochemical study
Shiozaki, K., Iseki, E., Hino, H., & Kosaka, K. (2001) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(01)00638-4 · Cited by 60
A model for experience-dependent changes in the responses of inferotemporal neurons
Sohal, V. S., & Hasselmo, M. E. (2000) · Network Computation in Neural Systems · doi:10.1088/0954-898x_11_3_301 · Cited by 58
Anatomy of rat semaphorin III collapsin‐1 mRNA expression and relationship to developing nerve tracts during neuroembryogenesis
Giger, R. J., Wolfer, D. P., de Wit, G. M. J., & Verhaagen, J. (1996) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19961118)375:3 · Cited by 191
Muscarinic receptor-mediated induction of Fos protein in rat brain
Hughes, P. E., & Dragunow, M. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90122-2 · Cited by 60
Effects of acetylcholine on neuronal properties in entorhinal cortex
Heys, J. G., Schultheiss, N. W., Shay, C. F., Tsuno, Y., & Hasselmo, M. E. (2012) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2012.00032 · Cited by 61
Age-related decline in cholinergic synaptic transmission in hippocampus
Taylor, L., & Griffith, W. H. (1993) · Neurobiology of Aging · doi:10.1016/0197-4580(93)90110-w · Cited by 59
Vasoactive Intestinal Polypeptide Microinjections into the Oral Pontine Tegmentum Enhance Rapid Eye Movement Sleep in the Rat
Bourgin, P., Lebrand, C., Escourrou, P., Gaultier, C., Franc, B., Hamon, M., & Adrien, J. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00455-1 · Cited by 59
The role of cortical cholinergic pre- and post-synaptic receptors in taste memory formation
Ramı́rez-Lugo, L., Miranda, M. I., Escobar, M. L., Espinosa, E., & Bermúdez‐Rattoni, F. (2003) · Neurobiology of Learning and Memory · doi:10.1016/s1074-7427(02)00038-2 · Cited by 55
Induction of Activity-Dependent LTD Requires Muscarinic Receptor Activation in Medial Prefrontal Cortex
Caruana, D. A., Warburton, E. C., & Bashir, Z. I. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4719-11.2011 · Cited by 55
Cholinergic modulation of synaptic transmission and plasticity in entorhinal cortex and hippocampus of the rat
Yun, S. H., Cheong, M. Y., Mook‐Jung, I., Huh, K. H., Lee, C.-J., & Jung, M. W. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00108-1 · Cited by 54
Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices
Wang, Y., Greig, N. H., Yu, Q.-S., & Mattson, M. P. (2008) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.10.009 · Cited by 53
Differential Effects of PACAP-38 on Synaptic Responses in Rat Hippocampal CA1 RegionPreprint
Roberto, M., Scuri, R., & Brunelli, M. (2001) · Learning & Memory · doi:10.1101/lm.40501 · Cited by 55
Facilitation of long-term potentiation in layer II/III horizontal connections of rat motor cortex following layer I stimulation: route of effect and cholinergic contributions
Hess, G., & Donoghue, J. P. (1999) · Experimental Brain Research · doi:10.1007/s002210050797 · Cited by 54
Enhanced cholinergic suppression of previously strengthened synapses enables the formation of self-organized representations in olfactory cortex
Linster, C., Maloney, M. E., Patil, M. M., & Hasselmo, M. E. (2003) · Neurobiology of Learning and Memory · doi:10.1016/s1074-7427(03)00078-9 · Cited by 56
PACAP-38 Enhances Excitatory Synaptic Transmission in the Rat Hippocampal CA1 RegionPreprint
Roberto, M., & Brunelli, M. (2000) · Learning & Memory · doi:10.1101/lm.34200 · Cited by 53
Effects of decabrominated diphenyl ether (PBDE 209) exposure at different developmental periods on synaptic plasticity in the dentate gyrus of adult rats In vivo.
Xing, T.-R., Chen, L., Tao, Y., Wang, M., Chen, J.-T., & Ruan, D.-Y. (2009) · Toxicological Sciences · doi:10.1093/toxsci/kfp114 · Cited by 58
Muscarinic suppression in stratum radiatum of CA1 shows dependence on presynaptic M1 receptors and is not dependent on effects at GABAB receptors
Kremin, T., GERBER, D., Giocomo, L. M., Huang, S., Tonegawa, S., & Hasselmo, M. E. (2005) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2005.09.005 · Cited by 52
Metrifonate improves associative learning and retention in aging rabbits.
Kronforst-Collins, M. A., Moriearty, P. L., Schmidt, B. H., & Disterhoft, J. F. (1997) · Behavioral Neuroscience · doi:10.1037//0735-7044.111.5.1031 · Cited by 51
Acute cholinergic rescue of synaptic plasticity in the neurodegenerating cortex of anti‐nerve‐growth‐factor mice
Pesavento, E., Capsoni, S., Domenici, L., & Cattaneo, A. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.01937.x · Cited by 53
Instantaneous acceleration and amplification of hippocampal theta wave coincident with phasic pontine activities during REM sleep
Karashima, A., Nakao, M., Katayama, N., & Honda, K. (2005) · Brain Research · doi:10.1016/j.brainres.2005.05.055 · Cited by 51
Differential presynaptic and postsynaptic expression of m1–m4 muscarinic acetylcholine receptors at the perforant pathway/granule cell synapse
Rouse, S. T., Gilmor, M. L., & Levey, A. I. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00681-7 · Cited by 50
Galanin inhibits long-term potentiation at Schaffer collateral-CA1 synapses in guinea-pig hippocampal slices
Sakurai, E., Maeda, T., Kaneko, S., Akaike, A., & Satoh, M. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12772-5 · Cited by 49
Cholinergic modulation of hippocampal CA1 basal-dendritic long-term potentiation
Doralp, S., & Leung, L.-W. S. (2008) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2008.05.013 · Cited by 47
Acetylcholine and associative memory in the piriform cortex
Barkai, E., & Hasselmo, M. E. (1997) · Molecular Neurobiology · doi:10.1007/bf02740613 · Cited by 45
Conditional associative learning and the hippocampal system
Sziklas, V., Lebel, S., & Petrides, M. (1998) · Hippocampus · doi:10.1002/(sici)1098-1063(1998)8:2 · Cited by 53
Cholinergic suppression of glutamatergic synaptic transmission in hippocampal region CA3 exhibits laminar selectivity: Implication for hippocampal network dynamics
Kremin, T., & Hasselmo, M. E. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.07.007 · Cited by 43
Muscarinic signaling is required for spike‐pairing induction of long‐term potentiation at rat Schaffer collateral‐CA1 synapses
Adams, S. V., Winterer, J., & Müller, W. S. (2004) · Hippocampus · doi:10.1002/hipo.10197 · Cited by 44
Participation of hippocampal cholinergic system in memory persistence for inhibitory avoidance in rats
Parfitt, G. M., Campos, R. C., Barbosa, Â. K., Koth, A. P., & Barros, D. M. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.12.001 · Cited by 43
Muscarinic acetylcholine neurotransmission enhances the late-phase of long-term potentiation in the hippocampal–prefrontal cortex pathway of rats in vivo: A possible involvement of monoaminergic systems
Lopes Aguiar, C., Romcy-Pereira, R. N., Escorsim Szawka, R., Galvis-Alonso, O. Y., Anselmo-Franci, J. A., & Pereira Leite, J. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.02.040 · Cited by 42
Cooperation between cholinergic and glutamatergic receptors are essential to induce BDNF‐dependent long‐lasting memory storage
Navakkode, S., & Körte, M. (2011) · Hippocampus · doi:10.1002/hipo.20902 · Cited by 42
Lack of expression of long-term potentiation in the dentate gyrus but not in the CA1 region of the hippocampus of μ-opioid receptor-deficient mice
Matthies, H., Schröeder, H., Becker, A., Loh, H. H., Höllt, V., & Krug, M. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(99)00203-8 · Cited by 40
Strategies That Support Declining Cholinergic Neurotransmission in Alzheimer’s Disease Patients
Sirviö, J. (1999) · Gerontology · doi:10.1159/000052759 · Cited by 40
Hippocampal grafts of acetylcholine-producing cells are sufficient to improve behavioural performance following a unilateral fimbria–fornix lesion
Dickinson-Anson, H., Aubert, I., Gage, F. H., & Fisher, L. J. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00543-5 · Cited by 40
Involvement of M2 receptor in an enhancement of long-term potentiation by carbachol in Schaffer collateral-CA1 synapses of hippocampal slices
Shimoshige, Y., Maeda, T., Kaneko, S., Akaike, A., & Satoh, M. (1997) · Neuroscience Research · doi:10.1016/s0168-0102(96)01147-9 · Cited by 39
Adaptive control of synaptic plasticity integrates micro- and macroscopic network function
Scott, D. N., & Frank, M. J. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01374-6 · Cited by 40
Cholinergic plasticity in the hippocampus
Colgin, L. L., Kubota, D., & LYNCH, G. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0530289100 · Cited by 36
Activation of pirenzepine-sensitive muscarinic receptors induces a specific pattern of immediate-early gene expression in rat brain neurons
Hughes, P. E., & Dragunow, M. (1994) · Molecular Brain Research · doi:10.1016/0169-328x(94)90129-5 · Cited by 35
θ-activity-dependent and -independent muscarinic facilitation of long-term potentiation in guinea pig hippocampal slices.
Natsume, K., & Kometani, K. (1997) · Neuroscience Research · doi:10.1016/s0168-0102(97)01167-x · Cited by 34
Alteration of cardiovascular and neuronal function in M1 knockout mice
Hamilton, S. E., Hardouin, S. N., Anagnostaras, S., Murphy, G. G., Richmond, K. N., Silva, A. J., Feigl, E. O., & Nathanson, N. M. (2001) · Life Sciences · doi:10.1016/s0024-3205(01)01043-8 · Cited by 34
Cellular Mechanisms Of Long-Term Potentiation: Late Maintenance
Frey, U. (1997) · Advances in psychology · doi:10.1016/s0166-4115(97)80092-1 · Cited by 33

Authors: Blitzer, R. D., Gil, O., & Landau, E. M.
Affiliations: United States Department of Veterans Affairs (US)
Mount Sinai Hospital (US)
Corresponding author: Blitzer, Robert D.
ORCID: Blitzer, Robert D.
Venue: Neuroscience Letters
Publisher: Elsevier BV
Published: 1990-11
Volume: 119
Issue: 2
Pages: 207-210
ISSN: 0304-3940 (ISSN-L)
DOI: 10.1016/0304-3940(90)90835-w
OpenAlex: W2071637530
Cited by: 192
References: 23
Citations by year: 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 3 · 2020: 4 · 2019: 4 · 2018: 8 · 2016: 3 · 2015: 1 · 2014: 4 · 2013: 5 · 2012: 8
FWCI: 1.70
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience Letters (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (AG-02219, P50AG005138, 5-P50-AG05138-02, P01AG002219)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
Keywords: long-term potentiation, cholinergic stimulation, carbachol, acetylcholine, hippocampal CA1, tetanic stimulation, presynaptic depression, postsynaptic mechanisms, memory
MeSH terms: Animals, Atropine, Carbachol, Electric Stimulation, Hippocampus, Male, Parasympathomimetics, Rats, Inbred Strains, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Cholinergic stimulation enhances long-term potentiation in the CA1 region of rat hippocampus

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks