Abstinence effects as predictors of 28-day relapse in smokers
Abstract
The present analysis sought to determine the relationship between abstinence effects in 64 ex-smokers (mean age = 41.1 years) and the rate at which they relapsed over 4 weeks of biochemically confirmed follow-up. This analysis focused on six abstinence effects that play a central role in the DSM-III-R and DSM IV definitions of withdrawal from nicotine: anger, depression, craving, appetite, confusion, and tension. Significant increases were observed for all six symptoms following cessation, and, with the exception of craving, substantial intercorrelations among the abstinence effects were noted. Cox proportional hazards survival models identified increases in anger, depressed mood, and craving to be significantly associated with a shorter time to relapse (all p < .03). Stepwise Cox proportional hazards survival analysis identified increases in depressed mood and craving as the most significant combination of abstinence effects in relation to time to relapse. A more stringent test of the potency of the relationship between these abstinence effects and time to relapse was conducted in which two other risk factors in this sample, method of quitting and education level, were also included in the model testing sequence. Even after adjustment for these significant risk factors, the increase in craving remained a significant predictor of a higher rate of relapse. This result suggests a robustness to this particular abstinence effect as a determinant of the speed with which ex-smokers relapse over a 1-month interval after cessation.
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From Nicotine addiction and psychiatric disorders (2015) · cites this paper as Swan et al., 1996
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- Authors
- Swan, G. E., Ward, M. M., & Jack, L. M.
- Affiliations
- SRI International (US)
- Corresponding author
- Swan, Gary E.
- Venue
- Addictive Behaviors
- Publisher
- Elsevier BV
- Published
- 1996-07
- Volume
- 21
- Issue
- 4
- Pages
- 481-490
- ISSN
- 0306-4603 (ISSN-L)
- OpenAlex
- W2055703665
- Cited by
- 150
- References
- 33
- Citations by year
- 2026: 1 · 2023: 3 · 2022: 2 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 4 · 2015: 7 · 2014: 10 · 2013: 5 · 2012: 5
- FWCI
- 2.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Addictive Behaviors (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
- Keywords
- nicotine withdrawal, smoking relapse, former smokers, craving, depression, anger, time to relapse, recurrence risk factors, educational attainment
- MeSH terms
- Adult, Female, Follow-Up Studies, Humans, Male, Neurologic Examination, Nicotine, Psychiatric Status Rating Scales, Risk Factors, Substance Withdrawal Syndrome, Smoking Cessation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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